Search results for: initial cell attachment.
838 Fuzzy Clustering Analysis in Real Estate Companies in China
Authors: Jianfeng Li, Feng Jin, Xiaoyu Yang
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This paper applies fuzzy clustering algorithm in classifying real estate companies in China according to some general financial indexes, such as income per share, share accumulation fund, net profit margins, weighted net assets yield and shareholders' equity. By constructing and normalizing initial partition matrix, getting fuzzy similar matrix with Minkowski metric and gaining the transitive closure, the dynamic fuzzy clustering analysis for real estate companies is shown clearly that different clustered result change gradually with the threshold reducing, and then, it-s shown there is the similar relationship with the prices of those companies in stock market. In this way, it-s great valuable in contrasting the real estate companies- financial condition in order to grasp some good chances of investment, and so on.
Keywords: Fuzzy clustering algorithm, data mining, real estate company, financial analysis.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1900837 Unsteady Boundary Layer Flow over a Stretching Sheet in a Micropolar Fluid
Authors: Roslinda Nazar, Anuar Ishak, Ioan Pop
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Unsteady boundary layer flow of an incompressible micropolar fluid over a stretching sheet when the sheet is stretched in its own plane is studied in this paper. The stretching velocity is assumed to vary linearly with the distance along the sheet. Two equal and opposite forces are impulsively applied along the x-axis so that the sheet is stretched, keeping the origin fixed in a micropolar fluid. The transformed unsteady boundary layer equations are solved numerically using the Keller-box method for the whole transient from the initial state to final steady-state flow. Numerical results are obtained for the velocity and microrotation distributions as well as the skin friction coefficient for various values of the material parameter K. It is found that there is a smooth transition from the small-time solution to the large-time solution.Keywords: Boundary layer, micropolar fluid, stretching surface, unsteady flow.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2343836 Flight Control of a Trirotor Mini-UAV for Enhanced Situational Awareness
Authors: Igor Astrov, Andrus Pedai
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This paper focuses on a critical component of the situational awareness (SA), the control of autonomous vertical flight for an unmanned aerial vehicle (UAV). Autonomous vertical flight is a challenging but important task for tactical UAVs to achieve high level of autonomy under adverse conditions. With the SA strategy, we proposed a two stage flight control procedure using two autonomous control subsystems to address the dynamics variation and performance requirement difference in initial and final stages of flight trajectory for a nontrivial nonlinear trirotor mini-UAV model. This control strategy for chosen mini-UAV model has been verified by simulation of hovering maneuvers using software package Simulink and demonstrated good performance for fast SA in realtime search-and-rescue operations.
Keywords: Flight control, trirotor aircraft, situational awareness, unmanned aerial vehicle.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2149835 Finite Element Simulation of Deep Drawing Process to Minimize Earing
Authors: Pawan S. Nagda, Purnank S. Bhatt, Mit K. Shah
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Earing defect in drawing process is highly undesirable not only because it adds on an additional trimming operation but also because the uneven material flow demands extra care. The objective of this work is to study the earing problem in the Deep Drawing of circular cup and to optimize the blank shape to reduce the earing. A finite element model is developed for 3-D numerical simulation of cup forming process in ABAQUS. Extra-deep-drawing (EDD) steel sheet has been used for simulation. Properties and tool design parameters were used as input for simulation. Earing was observed in the simulated cup and it was measured at various angles with respect to rolling direction. To reduce the earing defect initial blank shape was modified with the help of anisotropy coefficient. Modified blanks showed notable reduction in earing.Keywords: Finite element simulation, deep drawing, earing, anisotropy.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1975834 Viscoelastic Characterization of Bovine Trabecular Bone Samples
Authors: Ramirez D. Edgar I., Angeles H. José J., Ruiz C. Osvaldo, Jacobo A. Victor H., Ortiz P. Armando
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Knowledge of bone mechanical properties is important for bone substitutes design and fabrication, and more efficient prostheses development. The aim of this study is to characterize the viscoelastic behavior of bone specimens, through stress relaxation and fatigue tests performed to trabecular bone samples from bovine femoral heads. Relaxation tests consisted on preloading the samples at five different magnitudes and evaluate them for 1020 seconds, adjusting the results to a KWW mathematical model. Fatigue tests consisted of 700 load cycles and analyze their status at the end of the tests. As a conclusion we have that between relaxation stress and each preload there is linear relation and for samples with initial Young´s modulus greater than 1.5 GPa showed no effects due fatigue test loading cycles.Keywords: Bone viscoelasticity, fatigue test, stress relaxation test, trabecular bone properties.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2061833 Grading of Emulsified Agarwood Oil Using Gel Electrophoresis Technique
Authors: Y. T. Boon, M. N. Naim, R. Zakaria, N. F. Abu Bakar, N. Ahmad, I. W. Lenggoro
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In this study, encapsulation of agarwood oil with non-ionic surfactant, Tween 80 was prepared at critical micelle concentration of 0.0167 % v/v to produce the most stable nano-emulsion in aqueous. The encapsulation has minimized the bioactive compounds degradation in various pH conditions thus prolong their shelf life and maintained its initial oil grade. The oil grading of the prepared samples were conducted using the gel electrophoresis instead of using common analytical industrial grading such as gas chromatography- mass spectrometry (GC- MS). The grading method was chosen due to their unique zeta potential value after the encapsulation process. This paper demonstrates the feasibility of applying the electrophoresis principles to separate the encapsulated agarwood oil or grading of the emulsified agarwood oil. The results indicated that the grading process are potential to be further investigate based on their droplet size and zeta potential value at various pH condition when the droplet were migrate through polyacrylamide gel.Keywords: Electrophoretic mobility, essential oil, nanoemulsion, polyacrylamide gel electrophoresis, Tween 80, zeta potential.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2102832 An Innovation Capability Maturity Model – Development and Initial Application
Authors: H. Essmann, N. du Preez
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The seemingly ambiguous title of this paper – use of the terms maturity and innovation in concord – signifies the imperative of every organisation within the competitive domain. Where organisational maturity and innovativeness were traditionally considered antonymous, the assimilation of these two seemingly contradictory notions is fundamental to the assurance of long-term organisational prosperity. Organisations are required, now more than ever, to grow and mature their innovation capability – rending consistent innovative outputs. This paper describes research conducted to consolidate the principles of innovation and identify the fundamental components that constitute organisational innovation capability. The process of developing an Innovation Capability Maturity Model is presented. A brief description is provided of the basic components of the model, followed by a description of the case studies that were conducted to evaluate the model. The paper concludes with a summary of the findings and potential future research.
Keywords: Capability maturity, innovation, innovation capability.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 4168831 Optimization of CO2 Emissions and Cost for Composite Building Design with NSGA-II
Authors: Ji Hyeong Park, Ji Hye Jeon, Hyo Seon Park
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Environmental pollution problems have been globally main concern in all fields including economy, society and culture into the 21st century. Beginning with the Kyoto Protocol, the reduction on the emissions of greenhouse gas such as CO2 and SOX has been a principal challenge of our day. As most buildings unlike durable goods in other industries have a characteristic and long life cycle, they consume energy in quantity and emit much CO2. Thus, for green building construction, more research is needed to reduce the CO2 emissions at each stage in the life cycle. However, recent studies are focused on the use and maintenance phase. Also, there is a lack of research on the initial design stage, especially the structure design. Therefore, in this study, we propose an optimal design plan considering CO2 emissions and cost in composite buildings simultaneously by applying to the structural design of actual building.Keywords: Multi-objective optimization, CO2 emissions, structural cost, encased composite structure
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2141830 Strength Optimization of Induction Hardened Splined Shaft – Material and Geometric Aspects
Authors: I. Barsoum, F. Khan
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the current study presents a modeling framework to determine the torsion strength of an induction hardened splined shaft by considering geometry and material aspects with the aim to optimize the static torsion strength by selection of spline geometry and hardness depth. Six different spline geometries and seven different hardness profiles including non-hardened and throughhardened shafts have been considered. The results reveal that the torque that causes initial yielding of the induction hardened splined shaft is strongly dependent on the hardness depth and the geometry of the spline teeth. Guidelines for selection of the appropriate hardness depth and spline geometry are given such that an optimum static torsion strength of the component can be achieved.
Keywords: Static strength, splined shaft, torsion, induction hardening, hardness profile, finite element, optimization, design.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 4957829 Creep Constitutive Equation for 2- Materials of Weldment-304L Stainless Steel
Authors: Amir Hossein Daei Sorkhabi, Farid Vakili Tahami
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In this paper, creep constitutive equations of base (Parent) and weld materials of the weldment for cold-drawn 304L stainless steel have been obtained experimentally. For this purpose, test samples have been generated from cold drawn bars and weld material according to the ASTM standard. The creep behavior and properties have been examined for these materials by conducting uniaxial creep tests. Constant temperatures and constant load uni-axial creep tests have been carried out at two high temperatures, 680 and 720 oC, subjected to constant loads, which produce initial stresses ranging from 240 to 360 MPa. The experimental data have been used to obtain the creep constitutive parameters using numerical optimization techniques.Keywords: Creep, Constitutive equation, Cold-drawn 304L stainless steel, Weld, Base material
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2750828 The Active Imagination Technique for Bruxism Treatment
Authors: Lyra S. R., Zaura-Bremm T., Boleta-Ceranto D. C. F.
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The research purpose was to evaluate the effect of Active Imagination Technique (AIT) for bruxism treatment. This project was approved by the Ethics Committee on Human Research (CAAE: 05619512.9.0000.0109). Twenty-one volunteers using interocclusal splint completed the study. Initially they filled in a questionnaire about their condition, composed of objective questions on signs and symptoms. Following they were underwent asingle session of AIT. After 15 days, the volunteers met again the same initial questionnaire. The results were compared and showed that the vast majority had pain symptoms, difficulty opening the mouth, pain when chewing, reduced, some of the participants abandoned the interocclusal splint during the evaluate period. It is concluded that the technique can be used in bruxism treatment. Results seem to be promising and demonstrates the need of highlighting Active Imagination Technique since it points a possibility of bruxism cure and that is unprecedented.Keywords: Active Imagination, bruxism, orofacial pain, treatment
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2158827 Utilization of Schnerr-Sauer Cavitation Model for Simulation of Cavitation Inception and Super Cavitation
Authors: Mohammadreza Nezamirad, Azadeh Yazdi, Sepideh Amirahmadian, Nasim Sabetpour, Amirmasoud Hamedi
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In this study, the Reynolds-Stress-Navier-Stokes framework is utilized to investigate the flow inside the diesel injector nozzle. The flow is assumed to be multiphase as the formation of vapor by pressure drop is visualized. For pressure and velocity linkage, the coupled algorithm is used. Since the cavitation phenomenon inherently is unsteady, the quasi-steady approach is utilized for saving time and resources in the current study. Schnerr-Sauer cavitation model is used, which was capable of predicting flow behavior both at the initial and final steps of the cavitation process. Two different turbulent models were used in this study to clarify which one is more capable in predicting cavitation inception and super-cavitation. It was found that K-ε was more compatible with the Shnerr-Sauer cavitation model; therefore, the mentioned model is used for the rest of this study.
Keywords: CFD, RANS, cavitation, fuel, injector.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 520826 Cascaded H-Bridge Five Level Inverter Based Selective Harmonic Eliminated Pulse Width Modulation for Harmonic Elimination
Authors: S. Selvaperumal, M. S. Sivagamasundari
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In this paper, selective harmonic elimination pulse width modulation technique is employed to eliminate lower order harmonics like third by determination of solving non-linear equations. The cascaded H-bridge five level inverter is driven by the Peripheral Interface Controlled (PIC) Microcontroller 16F877A. The performance of single phase cascaded H-bridge five level inverter with relevant to harmonics and a variety of switches with solar cell as its input source is simulated by employing MATLAB/Simulink. A hardware model is developed to verify the performance of the developed system.
Keywords: Multilevel inverter, cascaded H-Bridge multilevel inverter, total harmonic distortion, selective harmonic elimination pulse width modulation, MATLAB.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 810825 The Analysis of TRACE/PARCS in the Simulation of Ultimate Response Guideline for Lungmen ABWR
Authors: J. R. Wang, W.Y. Li, H.T. Lin, B.H. Lee, C. Shih, S.W. Chen
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In this research, the TRACE/PARCS model of Lungmen ABWR has been developed for verification of ultimate response guideline (URG) efficiency. This ultimate measure was named as DIVing plan, abbreviated from system depressurization, water injection and containment venting. The simulation initial condition is 100% rated power/100% rated core flow. This research focuses on the estimation of the time when the fuel might be damaged with no water injection by using TRACE/PARCS first. Then, the effect of the reactor core isolation system (RCIC), control depressurization and ac-independent water addition system (ACIWA), which can provide the injection with 950 gpm are also estimated for the station blackout (SBO) transient.
Keywords: ABWR, TRACE, safety analysis, PARCS.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2211824 Motion Control of TUAV having Eight Rotors for Enhanced Situational Awareness
Authors: Igor Astrov, Andrus Pedai
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This paper focuses on a critical component of the situational awareness (SA), the control of autonomous vertical flight for tactical unmanned aerial vehicle (TUAV). With the SA strategy, we proposed a two stage flight control procedure using two autonomous control subsystems to address the dynamics variation and performance requirement difference in initial and final stages of flight trajectory for a nontrivial nonlinear eight-rotor helicopter model. This control strategy for chosen model of mini-TUAV has been verified by simulation of hovering maneuvers using software package Simulink and demonstrated good performance for fast stabilization of engines in hovering, consequently, fast SA with economy in energy of batteries can be asserted during search-andrescue operations.Keywords: Flight control, eight-rotor helicopter, situational awareness, tactical unmanned aerial vehicle
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1724823 Expected Present Value of Losses in the Computation of Optimum Seismic Design Parameters
Authors: J. García-Pérez
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An approach to compute optimum seismic design parameters is presented. It is based on the optimization of the expected present value of the total cost, which includes the initial cost of structures as well as the cost due to earthquakes. Different types of seismicity models are considered, including one for characteristic earthquakes. Uncertainties are included in some variables to observe the influence on optimum values. Optimum seismic design coefficients are computed for three different structural types representing high, medium and low rise buildings, located near and far from the seismic sources. Ordinary and important structures are considered in the analysis. The results of optimum values show an important influence of seismicity models as well as of uncertainties on the variables.
Keywords: Importance factors, optimum parameters, seismic losses, seismic risk, total cost.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1338822 Design and Fabrication of a Scaffold with Appropriate Features for Cartilage Tissue Engineering
Authors: S. S. Salehi, A. Shamloo
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Poor ability of cartilage tissue when experiencing a damage leads scientists to use tissue engineering as a reliable and effective method for regenerating or replacing damaged tissues. An artificial tissue should have some features such as biocompatibility, biodegradation and, enough mechanical properties like the original tissue. In this work, a composite hydrogel is prepared by using natural and synthetic materials that has high porosity. Mechanical properties of different combinations of polymers such as modulus of elasticity were tested, and a hydrogel with good mechanical properties was selected. Bone marrow derived mesenchymal stem cells were also seeded into the pores of the sponge, and the results showed the adhesion and proliferation of cells within the hydrogel after one month. In comparison with previous works, this study offers a new and efficient procedure for the fabrication of cartilage like tissue and further cartilage repair.Keywords: Cartilage tissue engineering, hydrogel, mechanical strength, mesenchymal stem cell.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1281821 Computational Simulations on Stability of Model Predictive Control for Linear Discrete-time Stochastic Systems
Authors: Tomoaki Hashimoto
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Model predictive control is a kind of optimal feedback control in which control performance over a finite future is optimized with a performance index that has a moving initial time and a moving terminal time. This paper examines the stability of model predictive control for linear discrete-time systems with additive stochastic disturbances. A sufficient condition for the stability of the closed-loop system with model predictive control is derived by means of a linear matrix inequality. The objective of this paper is to show the results of computational simulations in order to verify the effectiveness of the obtained stability condition.Keywords: Computational simulations, optimal control, predictive control, stochastic systems, discrete-time systems.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1835820 Methanol Concentration Sensitive SWCNT/Nafion Composites
Authors: Kyongsoo Lee, , Seong-Il Kim, Byeong-Kwon Ju
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An aqueous methanol sensor for use in direct methanol fuel cells (DMFCs) applications is demonstrated; the methanol sensor is built using dispersed single-walled carbon nanotubes (SWCNTs) with Nafion117 solution to detect the methanol concentration in water. The study is aimed at the potential use of the carbon nanotubes array as a methanol sensor for direct methanol fuel cells (DMFCs). The concentration of methanol in the fuel circulation loop of a DMFC system is an important operating parameter, because it determines the electrical performance and efficiency of the fuel cell system. The sensor is also operative even at ambient temperatures and responds quickly to changes in the concentration levels of the methanol. Such a sensor can be easily incorporated into the methanol fuel solution flow loop in the DMFC system.Keywords: methanol concentration, SWCNT, nafion composites
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1916819 An Investigation on the Effects of Injection Spray Cone on Propulsive Droplets in a Duct
Authors: M. Mojtahedpoor
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This paper addresses one important aspect of combustion system analysis, the spray evaporation and dispersion modeling. In this study we assume an empty cylinder which is as a simulator for a ramjet engine and the cylinder has been studied by cold flow. Four nozzles have the duties of injection which are located in the entrance of cylinder. The air flow comes into the cylinder from one side and injection operation will be done. By changing injection velocity and entrance air flow velocity, we have studied droplet sizing and efficient mass fraction of fuel vapor near and at the exit area. We named the mass of fuel vapor inside the flammability limit as the efficient mass fraction. Further, we decreased the initial temperature of fuel droplets and we have repeated the investigating again. To fulfill the calculation we used a modified version of KIVA-3V.Keywords: Ramjet, droplet sizing, injection velocity, air flowvelocity, efficient mass fraction..
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1379818 Performance Enhancement of Cellular OFDM Based Wireless LANs by Exploiting Spatial Diversity Techniques
Authors: S. Ali. Tajer, Babak H. Khalaj
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This paper represents an investigation on how exploiting multiple transmit antennas by OFDM based wireless LAN subscribers can mitigate physical layer error rate. Then by comparing the Wireless LANs that utilize spatial diversity techniques with the conventional ones it will reveal how PHY and TCP throughputs behaviors are ameliorated. In the next step it will assess the same issues based on a cellular context operation which is mainly introduced as an innovated solution that beside a multi cell operation scenario benefits spatio-temporal signaling schemes as well. Presented simulations will shed light on the improved performance of the wide range and high quality wireless LAN services provided by the proposed approach.
Keywords: Multiple Input Multiple Output (MIMO), Orthogonal Frequency Division Multiplexing (OFDM), and WirelessLocal Area Network (WLAN).
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1393817 Current Deflecting Wall: A Promising Structure for Minimising Siltation in Semi-Enclosed Docks
Authors: A. A. Purohit, A. Basu, K. A. Chavan, M. D. Kudale
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Many estuarine harbours in the world are facing the problem of siltation in docks, channel entrances, etc. The harbours in India are not an exception and require maintenance dredging to achieve navigable depths for keeping them operable. Hence, dredging is inevitable and is a costly affair. The heavy siltation in docks in well mixed tide dominated estuaries is mainly due to settlement of cohesive sediments in suspension. As such there is a need to have a permanent solution for minimising the siltation in such docks to alter the hydrodynamic flow field responsible for siltation by constructing structures outside the dock. One of such docks on the west coast of India, wherein siltation of about 2.5-3 m/annum prevails, was considered to understand the hydrodynamic flow field responsible for siltation. The dock is situated in such a region where macro type of semi-diurnal tide (range of about 5m) prevails. In order to change the flow field responsible for siltation inside the dock, suitability of Current Deflecting Wall (CDW) outside the dock was studied, which will minimise the sediment exchange rate and siltation in the dock. The well calibrated physical tidal model was used to understand the flow field during various phases of tide for the existing dock in Mumbai harbour. At the harbour entrance where the tidal flux exchanges in/out of the dock, measurements on water level and current were made to estimate the sediment transport capacity. The distorted scaled model (1:400 (H) & 1:80 (V)) of Mumbai area was used to study the tidal flow phenomenon, wherein tides are generated by automatic tide generator. Hydraulic model studies carried out under the existing condition (without CDW) reveal that, during initial hours of flood tide, flow hugs the docks breakwater and part of flow which enters the dock forms number of eddies of varying sizes inside the basin, while remaining part of flow bypasses the entrance of dock. During ebb, flow direction reverses, and part of the flow re-enters the dock from outside and creates eddies at its entrance. These eddies do not allow water/sediment-mass to come out and result in settlement of sediments in dock both due to eddies and more retention of sediment. At latter hours, current strength outside the dock entrance reduces and allows the water-mass of dock to come out. In order to improve flow field inside the dockyard, two CDWs of length 300 m and 40 m were proposed outside the dock breakwater and inline to Pier-wall at dock entrance. Model studies reveal that, during flood, major flow gets deflected away from the entrance and no eddies are formed inside the dock, while during ebb flow does not re-enter the dock, and sediment flux immediately starts emptying it during initial hours of ebb. This reduces not only the entry of sediment in dock by about 40% but also the deposition by about 42% due to less retention. Thus, CDW is a promising solution to significantly reduce siltation in dock.Keywords: Current deflecting wall, eddies, hydraulic model, macro tide, siltation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1251816 Production of Milk Clotting Protease by Rhizopus Stolonifer through Optimization of Culture Conditions
Authors: S. Gais, F. Fazouane, A. Mechakra
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The present study describes the biosynthesis of a milkclotting protease by solid state fermentation (SSF) of a locally isolated mould, Rhizopus stolonifer. The production medium was prepared using wheat bran at 50% (w/v). The production conditions are optimized by varying 7 parameters: carbon and nitrogen sources, medium moisture, temperature, pH, fermentation time and inoculum-s size. The maximum enzyme synthesis was measured after 96 h of incubation time at temperature of 28°C. The optimum pH determined was 6 and the inoculum size was 3.106spores/ml. The optimum initial moisture content is comprised between 50 to 70%. The formation of milk clotting protease is enhanced when galactose and peptone are used at 10% (w/v) and 1% (w/v) concentrations respectively. The maximum production of milk clotting protease is 120 US/ml.Keywords: Milk clotting activity, protease production, Rhizopus stolonifer, Solid state fermentation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2293815 Modeling of Alpha-Particles’ Epigenetic Effects in Short-Term Test on Drosophila melanogaster
Authors: Z. M. Biyasheva, M. Zh. Tleubergenova, Y. A. Zaripova, A. L. Shakirov, V. V. Dyachkov
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In recent years, interest in ecogenetic and biomedical problems related to the effects on the population of radon and its daughter decay products has increased significantly. Of particular interest is the assessment of the consequence of irradiation at hazardous radon areas, which includes the Almaty region due to the large number of tectonic faults that enhance radon emanation. In connection with the foregoing, the purpose of this work was to study the genetic effects of exposure to supernormal radon doses on the alpha-radiation model. Irradiation does not affect the growth of the cell, but rather its ability to differentiate. In addition, irradiation can lead to somatic mutations, morphoses and modifications. These damages most likely occur from changes in the composition of the substances of the cell. Such changes are epigenetic since they affect the regulatory processes of ontogenesis. Variability in the expression of regulatory genes refers to conditional mutations that modify the formation of signs of intraspecific similarity. Characteristic features of these conditional mutations are the dominant type of their manifestation, phenotypic asymmetry and their instability in the generations. Currently, the terms “morphosis” and “modification” are used to describe epigenetic variability, which are maintained in Drosophila melanogaster cultures using linkaged X- chromosomes, and the mutant X-chromosome is transmitted along the paternal line. In this paper, we investigated the epigenetic effects of alpha particles, whose source in nature is mainly radon and its daughter decay products. In the experiment, an isotope of plutonium-238 (Pu238), generating radiation with an energy of about 5500 eV, was used as a source of alpha particles. In an experiment in the first generation (F1), deformities or morphoses were found, which can be called "radiation syndromes" or mutations, the manifestation of which is similar to the pleiotropic action of genes. The proportion of morphoses in the experiment was 1.8%, and in control 0.4%. In this experiment, the morphoses in the flies of the first and second generation looked like black spots, or melanomas on different parts of the imago body; "generalized" melanomas; curled, curved wings; shortened wing; bubble on one wing; absence of one wing, deformation of thorax, interruption and violation of tergite patterns, disruption of distribution of ocular facets and bristles; absence of pigmentation of the second and third legs. Statistical analysis by the Chi-square method showed the reliability of the difference in experiment and control at P ≤ 0.01. On the basis of this, it can be considered that alpha particles, which in the environment are mainly generated by radon and its isotopes, have a mutagenic effect that manifests itself, mainly in the formation of morphoses or deformities.
Keywords: Alpha-radiation, genotoxicity, morphoses, radioecology, radon.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 921814 Photodegradation of Phenol Red in the Presence of ZnO Nanoparticles
Authors: T.K. Tan, P.S. Khiew, W.S. Chiu, S.Radiman, R.Abd-Shukor, N.M. Huang, H.N. Lim
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In our recent study, we have used ZnO nanoparticles assisted with UV light irradiation to investigate the photocatalytic degradation of Phenol Red (PR). The ZnO photocatalyst was characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), specific surface area analysis (BET) and UVvisible spectroscopy. X-ray diffractometry result for the ZnO nanoparticles exhibit normal crystalline phase features. All observed peaks can be indexed to the pure hexagonal wurtzite crystal structures, with the space group of P63mc. There are no other impurities in the diffraction peak. In addition, TEM measurement shows that most of the nanoparticles are rod-like and spherical in shape and fairly monodispersed. A significant degradation of the PR was observed when the catalyst was added into the solution even without the UV light exposure. In addition, the photodegradation increases with the photocatalyst loading. The surface area of the ZnO nanomaterials from the BET measurement was 11.9 m2/g. Besides the photocatalyst loading, the effect of some parameters on the photodegradation efficiency such as initial PR concentration and pH were also studied.
Keywords: Nanostructures, phenol red, zinc oxide, heterogeneous photocatalyst.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3147813 Active Contours with Prior Corner Detection
Authors: U.A.A. Niroshika, Ravinda G.N. Meegama
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Deformable active contours are widely used in computer vision and image processing applications for image segmentation, especially in biomedical image analysis. The active contour or “snake" deforms towards a target object by controlling the internal, image and constraint forces. However, if the contour initialized with a lesser number of control points, there is a high probability of surpassing the sharp corners of the object during deformation of the contour. In this paper, a new technique is proposed to construct the initial contour by incorporating prior knowledge of significant corners of the object detected using the Harris operator. This new reconstructed contour begins to deform, by attracting the snake towards the targeted object, without missing the corners. Experimental results with several synthetic images show the ability of the new technique to deal with sharp corners with a high accuracy than traditional methods.Keywords: Active Contours, Image Segmentation, Harris Operator, Snakes
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2261812 The Oxidative Damage Marker for Sodium Formate Exposure on Lymphocytes
Authors: Malinee Pongsavee
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Sodium formate is the chemical substance used for food additive. Catalase is the important antioxidative enzyme in protecting the cell from oxidative damage by reactive oxygen species (ROS). The resultant level of oxidative stress in sodium formatetreated lymphocytes was investigated. The sodium formate concentrations of 0.05, 0.1, 0.2, 0.4 and 0.6 mg/mL were treated in human lymphocytes for 12 hours. After 12 treated hours, catalase activity change was measured in sodium formate-treated lymphocytes. The results showed that the sodium formate concentrations of 0.4 and 0.6 mg/mL significantly decreased catalase activities in lymphocytes (P < 0.05). The change of catalase activity in sodium formate-treated lymphocytes may be the oxidative damage marker for detect sodium formate exposure in human.Keywords: Sodium formate, catalase activity, oxidative damage marker, toxicity.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1957811 Integral Operators Related to Problems of Interface Dynamics
Authors: Pa Pa Lin
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This research work is concerned with the eigenvalue problem for the integral operators which are obtained by linearization of a nonlocal evolution equation. The purpose of section II.A is to describe the nature of the problem and the objective of the project. The problem is related to the “stable solution" of the evolution equation which is the so-called “instanton" that describe the interface between two stable phases. The analysis of the instanton and its asymptotic behavior are described in section II.C by imposing the Green function and making use of a probability kernel. As a result , a classical Theorem which is important for an instanton is proved. Section III devoted to a study of the integral operators related to interface dynamics which concern the analysis of the Cauchy problem for the evolution equation with initial data close to different phases and different regions of space.
Keywords: Evolution, Green function, instanton, integral operators.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1219810 Structural Simulation of a 4H-Sic Based Optically Controlled Thyristor Using a GaAs Based Optically Triggered Power Transistor and Its Application to DC-DC Boost Converter
Authors: Srikanta Bose, S.K. Mazumder
Abstract:
In the present simulation work, an attempt is made to study the switching dynamics of an optically controlled 4HSiC thyristor power semiconductor device with the use of GaAs optically triggered power transistor. The half-cell thyristor has the forward breakdown of 200 V and reverse breakdown of more than 1000 V. The optically controlled thyristor has a rise time of 0.14 μs and fall time of 0.065 μs. The turn-on and turn-off delays are 0.1 μs and 0.06 μs, respectively. In addition, this optically controlled thyristor is used as a control switch for the DC-DC Boost converter. The pn-diode used for the converter has the forward drop of 2.8 V and reverse breakdown of around 400 V.
Keywords: 4H-SiC, Boost converter, Optical triggering, Power semiconductor device, thyristor.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1951809 Graft Copolymerization of Cellulose Acetate with Nitro-N-Amino Phenyl Maleimides
Authors: Azza. A. Al-Ghamdi, Abir. A. Abdel-Naby
Abstract:
The construction of Nitro -N-amino phenyl maleimide branches onto Cellulose acetate (CA) substrate by free radical graft copolymerization using benzoyl peroxide as initiator led to formation of highly thermal stable copolymers as shown from the results of gravimetric analysis (TGA). CA-g-2,4-dinitro amino phenyl maleimide exhibited higher thermal stability than the CA-g-4-nitro amino phenyl maleimide as shown from the initial decomposition temperature (To). This is due to the ability of nitro group to form hydrogen bonding with hydroxyl group of the glucopyranose ring which increases the crystallinity of polymeric matrix. The crystalline shapes representing the graft part are clearly distinct in the Emission scanning electron microscope (ESEM) morphology of the copolymer. A suggested reaction mechanism for the grafting process was also discussed.
Keywords: Cellulose acetate, crystallinity, graft copolymerization, thermal properties.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 721