Search results for: basic physical formulation

Authors: Adegoke Yinka Adebayo

Abstract:

An understanding of the critical product attributes that impact on in vivo performance is key to the production of safe and effective medicines. Thus, a key driver for our research is the development of new basic science and technology underpinning the development of new pharmaceutical products. Research includes the structure and properties of drugs and excipients, biopharmaceutical characterisation, pharmaceutical processing and technology and formulation and analysis.

Keywords: drug discovery, drug development, drug delivery

Procedia PDF Downloads 463

Authors: N. Tabatadze

Abstract:

The research aim is to study the physical and mechanical characteristics of hydraulic concrete in the surface active environment. The specific goal is to obtain high strength and low deformable concrete based on nano additives, resistant to the aggressive environment. As result of research, the alkali-silica reaction was improved (relative elongation 0,122 % of admixture instead of 0,126 % of basic concrete after 14 days). The aggressive environment impact on the strength of heavy concrete, fabricated on the basis of the hydraulic admixture with the penetrating waterproof additives also was improved (strength on compression R28=47,5 mPa of admixture instead of R28=35,8 mPa). Moreover, water absorption (W=0,59 % of admixture instead of W=1,41 %), water tightness (R14=37,9 mPa instead R14=28,7 mPa) and water-resistance (B=18 instead B=12). The basic parameters of concrete with admixture was improved in comparison with basic concrete.

Keywords: hydraulic concrete, alkali-silica reaction, water absorption, water-resistance

Procedia PDF Downloads 322

Authors: Dewi Hapsari Ratna Muninggar, M. Rizal Martua Damanik

Abstract:

The purpose of this study was to develop a formulation of instant Indonesian traditional pancake (Surabi) based on composite rice and soybean flour and supplemented with Torbangun (Coleus amboinicus Lour) powder as an alternative snack for ADHD (Attention Deficit Hyperactivity Disorder) children. Completely randomised factorial design by two factors which were the ratio of composite rice and soybean flour (75:25; 70:30; 65:35) as well as the addition of Torbangun powder (3%; 5%; 7%) was used in this study. This study revealed that the best formula was instant surabi with 65:35 composite rice and soybean flour and 5% addition of Torbangun powder by considering hedonic test result, functional aspect and nutrients contribution. Then, both chemical and physical characteristics from the best formula of instant surabi were measured. Nutrients content of the chosen instant surabi per 100 g wet basis were 62.68 g moisture, 1.30 g ash, 6.81 g protein, 0.75 g fat, 28.47 g carbohydrate, 88.62 mg calcium, 4.14 mg iron, and 144 kcal energy while physical characteristics, such as water activity, cohesiveness, and hardness were 0.97, 0.569, 5582.2 g force consecutively. The results of this research suggested that instant surabi which can be possibly beneficial for ADHD children had 65:35 for rice and soybean flour ratio as well as 5% for the addition of Torbangun powder.

Keywords: ADHD children, instant surabi, soybean, torbangun

Procedia PDF Downloads 118

Authors: Gelacio Juárez-Luna, Gustavo Ayala, Jaime Retama-Velasco

Abstract:

This paper shows the advantages of the material failure process simulation by improve finite elements with embedded discontinuities, using a new definition of traction vector, dependent on the discontinuity length and the angle. Particularly, two families of this kind of elements are compared: kinematically optimal symmetric and statically and kinematically optimal non-symmetric. The constitutive model to describe the behavior of the material in the symmetric formulation is a traction-displacement jump relationship equipped with softening after reaching the failure surface. To show the validity of this symmetric formulation, representative numerical examples illustrating the performance of the proposed formulation are presented. It is shown that the non-symmetric family may over or underestimate the energy required to create a discontinuity, as this effect is related with the total length of the discontinuity, fact that is not noticed when the discontinuity path is a straight line.

Keywords: variational formulation, strong discontinuity, embedded discontinuities, strain localization

Procedia PDF Downloads 757

Authors: Imran Khan Pathan, Anil Bhandari, Peeyush K. Sharma, Rakesh K. Patel, Suresh Purohit

Abstract:

Floating tablets of Marichyadi Vati were developed with an aim to prolong its gastric residence time and increase the bioavailability of drug. Rapid gastrointestinal transit could result in incomplete drug release from the drug delivery system above the absorption zone leading to diminished efficacy of the administered dose. The tablets were prepared by wet granulation technique, using HPMC E50 LV act as Matrixing agent, Carbopol as floating enhancer, microcrystalline cellulose as binder, sodium bi carbonate as effervescent agent with other excipients. The simplex lattice design was used for selection of variables for tablets formulation. Formulation was optimized on the basis of floating time and in vitro drug release. The results showed that the floating lag time for optimized formulation was found to be 61 second with about 97.32 % of total drug release within 3 hours. The in vitro release profiles of drug from the formulation could be best expressed zero order with highest linearity r2 = 0.9943. It was concluded that the gastroretentive drug delivery system can be developed for Marichyadi Vati containing piperine to increase the residence time of the drug in the stomach and thereby increasing bioavailability.

Keywords: piperine, Marichyadi Vati, gastroretentive drug delivery, floating tablet

Procedia PDF Downloads 429

Authors: C. Juntarasaid, T. Pulngern, S. Chucheepsakul

Abstract:

A formulation of postbuckling analysis of end supported rods under self-weight has been presented by the variational method. The variational formulation involving the strain energy due to bending and the potential energy of the self-weight, are expressed in terms of the intrinsic coordinates. The variational formulation is accomplished by introducing the Lagrange multiplier technique to impose the boundary conditions. The finite element method is used to derive a system of nonlinear equations resulting from the stationary of the total potential energy and then Newton-Raphson iterative procedure is applied to solve this system of equations. The numerical results demonstrate the postbluckled configurations of end supported rods under self-weight. This finite element method based on variational formulation expressed in term of intrinsic coordinate is highly recommended for postbuckling analysis of end-supported rods under self-weight.

Keywords: postbuckling, finite element method, variational method, intrinsic coordinate

Procedia PDF Downloads 127

Authors: Manoel Pereira, Alvaro Veiga, Camila Epprecht, Renato Costa

Abstract:

This paper introduces an empirical version of the Esscher transform for risk-neutral option pricing. Traditional parametric methods require the formulation of an explicit risk-neutral model and are operational only for a few probability distributions for the returns of the underlying. In our proposal, we make only mild assumptions on the pricing kernel and there is no need for the formulation of the risk-neutral model for the returns. First, we simulate sample paths for the returns under the physical distribution. Then, based on the empirical Esscher transform, the sample is reweighted, giving rise to a risk-neutralized sample from which derivative prices can be obtained by a weighted sum of the options pay-offs in each path. We compare our proposal with some traditional parametric pricing methods in four experiments with artificial and real data.

Keywords: esscher transform, generalized autoregressive Conditional Heteroscedastic (GARCH), nonparametric option pricing

Procedia PDF Downloads 462

Authors: Peter Pfeifer, Julian Pfeifer, Niko Pfeifer

Abstract:

Information processing is the focus of brain and cognition research. This work has a different perspective; it starts with behaviors. The detailed analysis of behaviors leads to the discovery that a significant proportion of them are based on only five basic drives. These basic drives are combinable, and the combinations result in the diversity of human behavior and thinking. The key elements are drive memories. They collect memories of drive-related situations and feelings. They contain variations of basic drives in numerous areas of life and build combinations with different meanings depending on the area. Human thinking could be explained with variations on these nested combinations of basic drives.

Keywords: cognition, psycholinguistics, psychology, psychophysiology of cognition

Procedia PDF Downloads 137

Authors: Michał Glet, Kamil Kaczyński

Abstract:

Counterfeit goods and documents are a global problem, which needs more and more sophisticated methods of resolving it. Existing techniques using watermarking or embedding symbols on objects are not suitable for all use cases. To address those special needs, we created complete system allowing authentication of paper documents and physical objects with flat surface. Objects are marked using orientation independent and resistant to camera noise 2D graphic codes, named DotAuth. Based on the identifier stored in 2D code, the system is able to perform basic authentication and allows to conduct more sophisticated analysis methods, e.g., relying on augmented reality and physical properties of the object. In this paper, we present the complete architecture, algorithms and applications of the proposed system. Results of the features comparison of the proposed solution and other products are presented as well, pointing to the existence of many advantages that increase usability and efficiency in the means of protecting physical objects.

Keywords: anti-forgery, authentication, paper documents, security

Procedia PDF Downloads 110

Authors: Arto Grasten

Abstract:

Given the rising trend in obesity in children and youth, age-related decline in moderate- to- vigorous-intensity physical activity (MVPA) in several Western, African, and Asian countries in addition to limited evidence of behavioral, affective, cognitive outcomes in physical education, it is important to clarify the motivational processes in physical education classes behind total MVPA engagement. The present study examined the full sequence of the Hierarchical Model of Motivation in physical education including motivational climate, basic psychological needs, intrinsic motivation, contextual behavior, affect, cognition, total MVPA, and associated links to body mass index (BMI) and gender differences. A cross-sectional data comprised self-reports and objective assessments of 770 middle school students (Mage = 13.99 ± .81 years, 52% of girls) in North-East Finland. In order to test the associations between motivational climate, psychological needs, intrinsic motivation, cognition, behavior, affect, and total MVPA, a path model was implemented. Indirect effects between motivational climate and cognition, behavior, affect and total MVPA were tested by setting basic needs and intrinsic motivation as mediators into the model. The findings showed that direct and indirect paths for girls and boys associated with different contextual outcomes and girls’ indirect paths were not related with total MVPA. Precisely, task-involving climate-mediated by physical competence and intrinsic motivation related to enjoyment, importance, and graded assessments within girls, whereas task-involving climate associated with enjoyment and importance via competence and autonomy, and total MVPA via autonomy, intrinsic motivation, and importance within boys. Physical education assessments appeared to be essential in motivating students to participate in greater total MVPA. BMI was negatively linked with competence and relatedness only among girls. Although, the current and previous empirical findings supported task-involving teaching methods in physical education, in some cases, ego-involving climate should not be totally avoided. This may indicate that girls and boys perceive physical education classes in a different way. Therefore, both task- and ego-involving teaching practices can be useful ways of driving behavior in physical education classes.

Keywords: achievement goal theory, assessment, enjoyment, hierarchical model of motivation, physical activity, self-determination theory

Procedia PDF Downloads 264

Authors: Mohammed Kamal Alhassan

Abstract:

The closeness of Turkey to Greece has often been a cause of many disagreements between the people of the two countries. This is against the backdrop of the fact that they have many things in common. In the past, the two countries have had unhealthy relations, which threatened to cut diplomatic ties between them. The 1996 Imia/ Kardak incident and the Öcalan crisis, for instance, nearly resulted in war between them. There were events that also brought the two countries together, for instance, the 1999 earthquake. This was because many lives were lost during the disaster. It is important to note that these events were duly covered by the media in the two countries. First of all, the study intends to look at the role of the media in the formulation of foreign policy in Turkey-Greece relations. It examines the role of the media in the formulation of foreign policy with particular emphasis on agenda-setting and positioning theories of the media as the theoretical framework. Also, the study will discuss the media landscapes in Turkey and Greece, the ownership pattern of the media sector and the relationship between media organizations and the government in the two countries. Moreover, the core foreign policy objectives of the countries will be delved into. Finally, the study employs a qualitative method to critically analyze the role of the media in the formulation of foreign policy in Turkey-Greece relations. It uses the invitation of the Former Prime Minister of Greece, George Andreas Papandreou, to the Ambassadors Conference in Turkey as a case study. In the end, the analysis will prove that, indeed, the media in Greece was effective in the formulation of foreign policy in its relations with Turkey.

Keywords: media organizations, foreign policy, government, diplomacy

Procedia PDF Downloads 89

Authors: Waleed Afzal Naveed, Muhammd Dildar Gogi, Muhammad Sufian, Muhammad Junaid Nisar, Mubashir Iqbal, Hafiz Muhammad Waqas Amjad, Muhammad Hamza Khaliq

Abstract:

Present study was carried out to evaluate the performance of Slow-Released Formulations (SRF) of methyl eugenol with Carnauba wax in orchard of University of Agriculture Faisalabad, Pakistan against fruit flies. Carnauba wax was mixed with methyl eugenol in nine ratios (10:90, 20:80, 30:70, 40:60, 50:50, 60:40, 70:30, 80:20 and 90:10). The results revealed that SRFCN-9 trapped 35.3 flies/day/trap, exhibited an attractancy index (AI) of 50.35%, proved strongly attractive SRFCN for B. zonata and was categorized as Class-III slow-released formulation (Attractive Index > 50%). The SRFCN-1, SRFCN-2, SRFCN-3, SRFCN-4, SRFCN-5, SRFCN-6, SRFCN-7 and SRFCN-8 trapped 2.0, 5.3, 3.3, 4.0, 5.7, 12.0, 9.7 and 14.3 flies/day/trap respectively exhibited an attractancy index (AI) of -70.73%, -37.25%, -55.55%, -48.93%, -34.61%, 1.40%, -9.37% and 10.25% Attractive Index respectively, proved little or non attractive slow-released formulation and was categorized as Class-I slow-released formulation for B. zonata (Attractive Index < 11%). Results revealed that the Slow-Released Formulation containing 10% Carnauba wax with 90% methyl eugenol trapped maximum number of flies of over 30 days.

Keywords: slow-released formulation, Bactrocera zonata, Carnauba wax, methyl euginol

Procedia PDF Downloads 233

Authors: Yu-Jen Chang, Yun Chen, Hei-Lam Wong

Abstract:

The Economic Lot Scheduling Problem (ELSP) is a valuable mathematical model that can support decision-makers to make scheduling decisions. The basic period approach is effective for solving the ELSP. The assumption for applying the basic period approach is that a product must use its maximum production rate to be produced. However, a product can lower its production rate to reduce the average total cost when a facility has extra idle time. The past researches discussed how a product adjusts its production rate under the common cycle approach. To the best of our knowledge, no studies have addressed how a product lowers its production rate under the basic period approach. This research is the first paper to discuss this topic. The research develops a simple fixed rate approach that adjusts the production rate of a product under the basic period approach to solve the ELSP. Our numerical example shows our approach can find a better solution than the traditional basic period approach. Our mathematical model that applies the fixed rate approach under the basic period approach can serve as a reference for other related researches.

Keywords: economic lot, basic period, genetic algorithm, fixed rate

Procedia PDF Downloads 541

Authors: Daniel O'Shea, Mario M. Attard, David C. Kellermann

Abstract:

In this paper, we propose a hyperelastic strain energy function that maps isotopic hyperelastic constitutive laws for the use of orthotropic materials without the use of structural tensors or any kind of fiber vector, or the use of standard invariants. In particular, we focus on neo-Hookean class of models and represent them using an invariant-free formulation. To achieve this, we revise the invariant-free formulation of isotropic hyperelasticity. The formulation uses quadruple contractions between fourth-order tensors, rather than scalar products of scalar invariants. We also propose a new decomposition of the orthotropic Hookean stiffness tensor into two fourth-order Lamé tensors that collapse down to the classic Lamé parameters for isotropic continua. The resulting orthotropic hyperelastic model naturally maintains all of the advanced properties of the isotropic counterparts, and similarly collapse back down to their isotropic form by nothing more than equality of parameters in all directions (isotropy). Comparisons are made with large strain experimental results for transversely isotropic rubber type materials under tension.

Keywords: finite strain, hyperelastic, invariants, orthotropic

Procedia PDF Downloads 415

Authors: Emmanuelle Merat, Arnaud Aubert, Sophie Cambos, Francis Vial, Patrick Beau

Abstract:

Basically, consumers are sensitive to many stimuli when applying a cream: brand, packaging and indeed formulation compositions. Many studies demonstrated the influence of some stimuli such as brand, packaging, formula color and odor (e.g. in make-up applications). Those parameters influence perceived quality of the product. The objective of this work is to further investigate the relationship between nude skincare basic compositions with different textures and consumer experience. A tentative final step will be to connect the consumer feelings with key ingredients in the compositions. A new approach was developed to better understand touch-related subjective experience in consumers based on a combination of methods: sensory analysis with ten experts, preference mapping on one hundred female consumers and emotional assessments on thirty consumers (verbal and non-verbal through prosody and gesture monitoring). Finally, a methodology based on ‘sensorial trip’ (after olfactory, haptic and musical stimuli) has been experimented on the most interesting textures with 10 consumers. The results showed more or less impact depending on compositions and also on key ingredients. Three types of formulation particularly attracted the consumer: an aqueous gel, an oil-in-water emulsion, and a patented gel-in-oil formulation type. Regarding these three formulas, the preferences were both revealed through sensory and emotion tests. One was recognized as the most innovative in consumer sensory test whereas the two other formulas were discriminated in emotions evaluation. The positive emotions were highlighted especially in prosody criteria. The non-verbal analysis, which corresponds to the physical parameters of the voice, showed high pitch and amplitude values; linked to positive emotions. Verbatim, verbal content of responses (i.e., ideas, concepts, mental images), confirmed the first conclusion. On the formulas selected for their positive emotions generation, the ‘sensorial trip’ provided complementary information to characterize each emotional profile. In the second step, dedicated to better understand ingredients power, two types of ingredients demonstrated an obvious input on consumer preference: rheology modifiers and emollients. As a conclusion, nude cosmetic compositions with well-chosen textures and ingredients can positively stimulate consumer emotions contributing to capture their preference. For a complete achievement of the study, a global approach (Asia, America territories...) should be developed.

Keywords: sensory, emotion, cosmetic formulations, ingredients' influence

Procedia PDF Downloads 157

Authors: Muhammad Yusuf Sulfarano Barusman

Abstract:

Research for the strategic formulation of competitive advantage development on Indonesian Private Higher Education Institutions (IPHEI) is mostly done using positivistic paradigm by means of analytical thinking. This study emphasized of the participatory paradigm by using synthesis as a way of thinking in order to achieve its goal. The purposes of this study are to: 1) build future scenario of the external environmental dynamics that will be encountered by IPHEI, 2) formulate a strategy that can be implemented by IPHEI through developing the organization's competitive advantage in the future. The used research methodology is Participatory Prospective Analysis (PPA). The results showed that the future scenario of external environmental conditions that will be encountered by IPHEI in the future can be described in three conditions, namely: optimistic, moderate, and pessimistic scenarios. The strategic formulation from the research results is based on four internal factors as its foundation (the effectiveness of leadership, the availability of funds and financing, the effectiveness of human resource management strategy, and the relevance of curriculum). A set of resulted strategic formulation is knowledge of the experts that needed to be followed up wisely so that their use can be optimized for the development of IPHE organizational competitive advantage in the future.

Keywords: competitive advantage, participatory prospective analysis, PPA, private higher education institutions, PHEI, strategic formulation

Procedia PDF Downloads 264

Authors: Fatemeh Deldarabdolmaleki, Nur Dalilah Dahlan, Farzad Hejazi

Abstract:

Human individual physiological and psycho-physical responses widely affect thermal comfort and preferences. They should be carefully researched to help improve the design and comfort of indoor environments. This paper aims to explore and test the degree and importance of individual physiological and psycho-physical differences, reviewing the most preferred, neutral, and comfortable temperature in previous studies conducted across the world. Basic individual physiological differences like gender, age, BMI and etc., have been the focus of this research. There is no unique consensus in the literature to date in regard to providing a universal thermal comfort formula that meets all individual physiological and psycho-physical needs. In order to achieve a balanced, thermally comfortable indoor environment, studying and evaluating individual needs in different parts of the world could be helpful. Even though personalized comfort systems in indoor environments sound promising, they might not be easily achieved in bigger office interiors, considering the cost and current open-plan office trends.

Keywords: thermal comfort, indoor environments, occupants' physiological response, occupants psycho-physical response

Procedia PDF Downloads 48

Authors: S. Periyadharshini, K. Ramkumar, S. Jayalalitha, M. GuruPrasath, R. Manikandan

Abstract:

This paper presents a formulation and solution for industrial load management and product grade problem. The formulation is created using linear programming technique thereby optimizing the electricity cost by scheduling the loads satisfying the process, storage, time zone and production constraints which will create an impact of reducing maximum demand and thereby reducing the electricity cost. Product grade problem is formulated using integer linear programming technique of optimization using lingo software and the results show that overall increase in profit margin. In this paper, time of use tariff is utilized and this technique will provide significant reductions in peak electricity consumption.

Keywords: cement industries, integer programming, optimal formulation, objective function, constraints

Procedia PDF Downloads 551

Authors: Abhishek Pandey

Abstract:

Ibuprofen and Acetaminophen is widely used as prescription & non-prescription medicine. Ibuprofen mainly used in the treatment of mild to moderate pain related to headache, migraine, postoperative condition and in the management of spondylitis, osteoarthritis and rheumatoid arthritis. Acetaminophen is used as an analgesic and antipyretic drug. Ibuprofen having high tendency of sticking to punches of tablet punching machine while Acetaminophen is not ordinarily compressible to tablet formulation because Acetaminophen crystals are very hard and brittle in nature and fracture very easily when compressed producing capping and laminating tablet defects therefore wet granulation method is used to make them compressible. The aim of study was to prepare Ibuprofen and Acetaminophen tablets by direct compression and top spray granulation technique. In this Investigation tablets were prepared by using directly compressible grade excipients. Dibasic calcium phosphate, lactose anhydrous (DCL21), microcrystalline cellulose (Avicel PH 101). In order to obtain best or optimized formulation, nine different formulations were generated among them batch F7, F8, F9 shows good results and within the acceptable limit. Formulation (F7) selected as optimize product on the basis of dissolution study. Furtherly, directly compressible granules of both drugs were prepared by using top spray granulation technique in fluidized bed processor equipment and compressed .In order to obtain best product process optimization was carried out by performing four trials in which various parameters like inlet air temperature, spray rate, peristaltic pump rpm, % LOD, properties of granules, blending time and hardness were optimized. Batch T3 coined as optimized batch on the basis physical & chemical evaluation. Finally formulations prepared by both techniques were compared.

Keywords: direct compression, top spray granulation, process optimization, blending time

Procedia PDF Downloads 335

Authors: Abhay Asthana, Shally Toshkhani, Gyati Shilakari

Abstract:

The present research was aimed to develop a biodegradable dermal patch formulation for wound healing in a novel, sustained and systematic manner. The goal is to reduce the frequency of dressings with improved drug delivery and thereby enhance therapeutic performance. In present study optimized formulation was designed using component polymers and excipients (e.g. Hydroxypropyl methyl cellulose, Ethylcellulose, and Gelatin) to impart significant folding endurance, elasticity and strength. Gelatin was used to get a mixture using ethylene glycol. Chitosan dissolved in suitable medium was mixed with stirring to gelatin mixture. With continued stirring to the mixture Curcumin was added in optimized ratio to get homogeneous dispersion. Polymers were dispersed with stirring in final formulation. The mixture was sonicated casted to get the film form. All steps were carried out under under strict aseptic conditions. The final formulation was a thin uniformly smooth textured film with dark brown-yellow color. The film was found to have folding endurance was around 20 to 21 times without a crack in an optimized formulation at RT (23C). The drug content was in range 96 to 102% and it passed the content uniform test. The final moisture content of the optimized formulation film was NMT 9.0%. The films passed stability study conducted at refrigerated conditions (4±0.2C) and at room temperature (23 ± 2C) for 30 days. Further, the drug content and texture remained undisturbed with stability study conducted at RT 23±2C for 45 and 90 days. Percentage cumulative drug release was found to be 80% in 12 h and matched the biodegradation rate as drug release with correlation factor R2 > 0.9. The film based formulation developed shows promising results in terms of stability and release profiles.

Keywords: biodegradable, patch, bioactive, polymer

Procedia PDF Downloads 489

Authors: Natia Tabatadze

Abstract:

The research aim is to study the physical - mechanical characteristics of structural materials, in particular, hydraulic concrete in the surface active environment and receiving of high strength concrete, low-deformable, resistant to aggressive environment concrete due application of nano technologies. The obtained concrete with additives will by possible to apply in hydraulic structures. We used cement (compressive strength R28=39,42 mPa), sand (0- 5 mm), gravel (5-10 mm, 10-20 mm), admixture CHRYSO® Fuge B 1,5% dosage of cement. CHRYSO® Fuge B renders mortar and concrete highly resistant to capillary action and reduces, or even eliminates infiltration of water under pressure. The fine particles that CHRYSO® Fuge B contains combine with the lime in the cement to form water repellent particles. These obstruct the capillary action within concrete. CHRYSO® Fuge B does not significantly modify the characteristics of the fresh concrete and mortar, nor the compressive strength. As result of research, the alkali-silica reaction was improved (relative elongation 0,122 % of admixture instead of 0,126 % of basic concrete after 14 days). The aggressive environment impact on the strength of heavy concrete, fabricated on the basis of the hydraulic admixture with the penetrating waterproof additives also was improved (strength on compression R28=47,5 mPa of admixture instead of R28=35,8 mPa), as well as the mass water absorption (W=3,37 % of admixture instead of W=1,41 %), volume water absorption (W=1,41 % of admixture instead of W=0,59 %), water tightness (R14=37,9 mPa instead R14=28,7 mPa) and water-resistance (B=18 instead B=12). The basic parameters of concrete with admixture was improved in comparison with basic concrete.

Keywords: structural materials, hydraulic concrete, low-deformable, water absorption for mass, water absorption for volume

Procedia PDF Downloads 294

Authors: Amalia Dwi Berliyanti Amel

Abstract:

Streptococcus mutants bacteria are bacteria that are believed to be the cause of the growth of dental plaque which can further adversely affect dental caries if left unchecked. Previous research has shown that Moringa leaf extract can slow down the growth rate of this bacterium. This study aims to make the best formulation of mouthwash with the active ingredient of Moringa leaf extract based on its antibacterial and organoleptic test results. Nine mouthwash variations were carried out with two factors and three levels, namely a comparison of the concentration of sorbitol (A) with three levels namely 15% (A1), 20% (A2), and 25% (A3), and peppermint added (B) with three levels, namely 0.2% (B1), 0.25% (B2), and 0.3% (B3). The test parameters performed as the determination of the best mouthwash are based on physicochemical properties which include pH and viscosity as well as organoleptic test results which include color, viscosity, aroma, taste, sensation in the mouth, and general appearance. The results showed that the bright zone as a test for the antibacterial activity of Streptococcus mutants began to be seen at a concentration of 5%. Moringa leaf mouthwash formulation has a pH value between 6 - 7, with a control of 6. Whereas the mucosa leaf mouthwash vascularity produced between 1.1 - 1.7 cP with a control of 1.1 cP. Moringa leaf mouthwash and control have the same total number of microbes, namely 0 colonies / mL. Based on organoleptic tests performed with 20 panelists, it was shown that the best mouthwash formulation was formulation A1B3 with sorbitol composition 15% and peppermint 0.3%.

Keywords: antibasteria, formula, moringa leaf, mouthwash

Procedia PDF Downloads 122

Authors: F. Sallem, B. Dahhou, A. Kamoun

Abstract:

In this work, the main problem considered is the detection and the isolation of the actuator fault. A new formulation of the linear system is generated to obtain the conditions of the actuator fault diagnosis. The proposed method is based on the representation of the actuator as a subsystem connected with the process system in cascade manner. The designed formulation is generated to obtain the conditions of the actuator fault detection and isolation. Detectability conditions are expressed in terms of the invertibility notions. An example and a comparative analysis with the classic formulation illustrate the performances of such approach for simple actuator fault diagnosis by using the linear model of nuclear reactor.

Keywords: actuator fault, Fault detection, left invertibility, nuclear reactor, observability, parameter intervals, system inversion

Procedia PDF Downloads 366

Authors: Fatemeh Ansarniya, Fatemeh Mirjalili, Hamid Reza Abedini, Shabnam Salari, M. Horasht

Abstract:

The study of this research is the effect of using Fe₂O₃ and sum of alkalis elements in the floor tile production. At first, raw materials of floor tile with the same formulation of original sample was prepared and sintered for 39 minutes at 1130˚C in roller kiln and finally, physical properties of the sintered bodies based on floor tile standard process was investigated. The results showed that there was the possibility of production of floor tile containing different percentages of Fe₂O₃ and sum of Na₂O+ K₂O. With increasing the Fe₂O₃ and sum of Na₂O+ K₂O elements, the percentages of water absorption and raw, dry and sintered strengths were decreased, but the percentages of shrinkage were increased which caused the decreasing the percentages of expansion.

Keywords: floor tile, physical properties, Na2O+ K2O, Fe2O3

Procedia PDF Downloads 484

Authors: Hebatullah Ali Abdel-Aleem Abdel-Hamid, Camellia Mousa Mohamed Elzean

Abstract:

Knitted garments recently became a key component in wardrobes of the Egyptian woman. Many Egyptian women depend on garments made of knitted fabrics in their outer appearance because of its specific properties including flexibility. Through observation and application, it was noticed that knitwear blocks that used for knitted fabrics somehow does not fit the figures of the Egyptian women. Moreover, the pattern makers are usually confused and unable to choose the suitable blocks for different knitting fabrics taking into consideration its physical and mechanical properties. This study seeks to develop mathematical relationships for evaluation of the amount of added- or subtracted ease to Aldrich’s basic fitting blocks for some weft knitting fabrics and its fitting to the upper part of Egyptian women's bodies. To achieve this goal, 12 samples were used to evaluate fitting of Aldrich’s Basic Fitting Block to the upper part of Egyptian women's bodies. The samples were evaluated before and after alterations, through wear trials on the standard mannequins of size 48 and 56, and judged by experienced assessors using fit evaluation scale. The data obtained were statistically analyzed to identify the efficiency of the adjustments. The Aldrich’s Basic Fitting Block was selected because his method is known internationally and easy to use.

Keywords: Aldrich basic fitting block, clothing industry, knitted fabrics, pattern construction

Procedia PDF Downloads 242

Authors: Celeste Labuschagne, Sam Ramaila, Thasmai Dhurumraj

Abstract:

Although formative assessment is acknowledged as crucial for teachers to gauge students’ understanding of subject content, applying formative assessment in an online context is more challenging than in a traditional Physical Sciences classroom. This study examines challenges experienced by Grade 10 Physical Sciences teachers when enacting online formative assessment. The empirical investigation adopted a generic qualitative design and involved three purposively selected Grade 10 Physical Sciences teachers from three different schools and quintiles within the Tshwane North District in South Africa. Data were collected through individual and focus group interviews. Technological, pedagogical, and content knowledge (TPACK) was utilised as a theoretical framework underpinning the study. The study identified a myriad of challenges experienced by Grade 10 Physical Sciences teachers when enacting online formative assessment. These challenges include the utilisation of Annual Teaching Plans, lack of technological knowledge, and internet connectivity. The Department of Basic Education faces the key imperative to provide continuous teacher professional development and concomitant online learning materials that can facilitate meaningful enactment of online formative assessment in various educational settings.

Keywords: COVID-19, challenges, online formative assessment, physical sciences, TPACK

Procedia PDF Downloads 42

Authors: Dahiru Bawa Muhammad

Abstract:

Mathematics is accorded a prime position in basic education curriculum because it is envisaged to be an important tool in preparing children for life after school as well as equipping them with skills needed for secondary and higher education. As a result of this, the subject is made compulsory from primary through secondary school and candidates are expected to offer it and pass before fulfilling the requirement for higher education. Against this backdrop, this paper overviewed the basic education programme, context of teaching and learning mathematics at basic education level in Katsina State of Nigeria, relevance of the subject to different fields of human endeavours, challenges threatening the utility of the subject as a tool for the achievement of the goals of basic education programme and concluded by recommending how teaching and learning of mathematics can be improved for even development of citizens within nation states and enhanced/mutual sustainable development of nations in the global village.

Keywords: basic education, junior secondary school education, mathematical centre

Procedia PDF Downloads 424

Authors: Waleed Afzal Naveed, Muhammd Dildar Gogi, Muhammad Sufian, Muhammad Amjad Ali, Muhammad Junaid Nisar, Mubashar Iqbal, Amna Jalal, Faisal Munir

Abstract:

The study was carried out to evaluate the performance of Slow-Released Formulations (SRF) of Methyl eugenol with Lanolin wax in orchard of the University of Agriculture Faisalabad, Pakistan against fruit flies. Lanolin wax was mixed with methyl eugenol in nine ratios (10:90, 20:80, 30:70, 40:60, 50:50, 60:40, 70:30, 80:20 and 90:10). The results revealed that SRFₗₗ-7 trapped 42.1 flies /day/trap, exhibited an attractancy index (AI) of 51.71%, proved strongly attractive SRFₗₗ for B. zonata and was categorized as Class-III slow-released formulation (AI > 50%). The SRFₗₗ-2, SRFₗₗ-3, SRFₗₗ-4, SRFₗₗ-5, SRFₗₗ-6, SRFₗₗ-8 and SRFₗₗ-9 trapped 17.7, 27.9, 32.3, 23.8, 28.3, 37.8 and 19.9 flies /day/trap, exhibited an attractancy index (AI) of 20.54%, 41.02%, 26.00%, 34.15%, 43.50%, 49.86% and 46.07% AI respectively, proved moderately attractive slow-released formulations for B. zonata and were categorized as Class-II slow-released formulations (AI = 11-50%). However, SRFₗₗ-1 trapped 14.8 flies /day/trap, exhibited 0.71% AI proved little or nonattractive slow-released formulation and was categorized as Class-I slow-released formulation for B. zonata (AI < 11%).

Keywords: Bactrocera zonata, slow-released formulation, lenoline wax, methyl euginol

Procedia PDF Downloads 208

Authors: Farzad Khajavi, Farzaneh Jalilfar, Faranak Jafari, Leila Shokrani

Abstract:

Formulation of gliclazide in the form of extended-release tablet in 30 and 60 mg dosage forms was performed using hypromellose (HPMC K4M) as a retarding agent. Drug-release profiles were investigated in comparison with references Diamicron MR 30 and 60 mg tablets. The effect of size of powder particles, the amount of hypromellose in formulation, hardness of tablets, and also the effect of halving the tablets were investigated on drug release profile. A mathematical model which describes hypromellose behavior in initial times of drug release was proposed for the estimation of hypromellose content in modified-release gliclazide 60 mg tablet. This model is based on erosion of hypromellose in dissolution media. The model is applicable to describe release profiles of insoluble drugs. Therefore, by using dissolved amount of drug in initial times of dissolution and the model, the amount of hypromellose in formulation can be predictable. The model was used to predict the HPMC K4M content in modified-release gliclazide 30 mg and extended-release quetiapine 200 mg tablets.

Keywords: Gliclazide, hypromellose, drug release, modified-release tablet, mathematical model

Procedia PDF Downloads 198

Authors: Samira Laidaoui, Mohammed Djermane, Nazihe Terfaya

Abstract:

The fluid-structure coupling is a natural phenomenon which reflects the effects of two continuums: fluid and structure of different types in the reciprocal action on each other, involving knowledge of elasticity and fluid mechanics. The solution for such problems is based on the relations of continuum mechanics and is mostly solved with numerical methods. It is a computational challenge to solve such problems because of the complex geometries, intricate physics of fluids, and complicated fluid-structure interactions. The way in which the interaction between fluid and solid is described gives the largest opportunity for reducing the computational effort. In this paper, a problem of fluid structure interaction is investigated with two-way coupling method. The formulation Arbitrary Lagrangian-Eulerian (ALE) was used, by considering a dynamic grid, where the solid is described by a Lagrangian formulation and the fluid by a Eulerian formulation. The simulation was made on the ANSYS software.

Keywords: ALE, coupling, FEM, fluid-structure, interaction, one-way method, two-way method

Procedia PDF Downloads 652