Search results for: Hamed Bazrafshan
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 74

Search results for: Hamed Bazrafshan

74 Photocatalytic Degradation of Produced Water Hydrocarbon of an Oil Field by Using Ag-Doped TiO2 Nanoparticles

Authors: Hamed Bazrafshan, Saeideh Dabirnia, Zahra Alipour Tesieh, Samaneh Alavi, Bahram Dabir

Abstract:

In this study, the removal of pollutants of a real produced water sample from an oil reservoir (a light oil reservoir), using a photocatalytic degradation process in a cylindrical glass reactor, was investigated. Using TiO2 and Ag-TiO2 in slurry form, the photocatalytic degradation was studied by measuring the Chemical Oxygen Demand (COD) parameter, qualitative analysis, and GC-MS. At first, optimization of the parameters on photocatalytic degradation of hydrocarbon pollutants in real produced water, using TiO2 nanoparticles as photocatalysts under UV light, was carried out applying response surface methodology. The results of the design of the experiment showed that the optimum conditions were at a catalyst concentration of 1.14 g/lit and pH of 2.67, and the percentage of COD removal was 72.65%.

Keywords: Photocatalyst, Ag-doped, TiO2, produced water, nanoparticles.

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73 Debye Layer Confinement of Nucleons in Nuclei by Laser Ablated Plasma

Authors: M. Ghanaatian, N. Ghahramany, A. Bazrafshan

Abstract:

Following the laser ablation studies leading to a theory of nuclei confinement by a Debye layer mechanism, we present here numerical evaluations for the known stable nuclei where the Coulomb repulsion is included as a rather minor component especially for lager nuclei. In this research paper the required physical conditions for the formation and stability of nuclei particularly endothermic nuclei with mass number greater than to which is an open astrophysical question have been investigated. Using the Debye layer mechanism, nuclear surface energy, Fermi energy and coulomb repulsion energy it is possible to find conditions under which the process of nucleation is permitted in early universe. Our numerical calculations indicate that about 200 second after the big bang at temperature of about 100 KeV and subrelativistic region with nucleon density nearly equal to normal nuclear density namely, 10cm all endothermic and exothermic nuclei have been formed.

Keywords: Endothermic nuclear synthesis, Fermi energy, Surface tension, Debye length.

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72 Isolation and Identification of Diacylglycerol Acyltransferase Type- 2 (GAT2) Genes from Three Egyptian Olive Cultivars

Authors: Yahia I. Mohamed, Ahmed I. Marzouk, Mohamed A. Yacout

Abstract:

Aim of this work was to study the genetic basis for oil accumulation in olive fruit via tracking DGAT2 (Diacylglycerol acyltransferase type-2) gene in three Egyptian Origen Olive cultivars namely Toffahi, Hamed and Maraki using molecular marker techniques and bioinformatics tools. Results illustrate that, firstly: specific genomic band of Maraki cultivars was identified as DGAT2 (Diacylglycerol acyltransferase type-2) and identical for this gene in Olea europaea with 100% of similarity. Secondly, differential genomic band of Maraki cultivars which produced from RAPD fingerprinting technique reflected predicted distinguished sequence which identified as DGAT2 (Diacylglycerol acyltransferase type-2) in Fragaria vesca subsp. Vesca with 76% of sequential similarity. Third and finally, specific genomic specific band of Hamed cultivars was identified as two fragments, 1- Olea europaea cultivar Koroneiki diacylglycerol acyltransferase type 2 mRNA, complete cds with two matches regions with 99% or 2- Predicted: Fragaria vesca subsp. vesca diacylglycerol O-acyltransferase 2-like (LOC101313050), mRNA with 86 % of similarity.

Keywords: Olea europaea, fingerprinting, Diacylglycerol acyltransferase type- 2 (DGAT2).

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71 Synthesizing an Artificial Loess for Geotechnical Investigations of Collapsible Soil Behavior

Authors: Hamed Sadeghi, Pouya A. Panahi, Hamed Nasiri, Mohammad Sadeghi

Abstract:

Collapsible soils like loess comprise an important category of problematic soils for construction purposes and sustainable development. As a result, research on both geological and geotechnical aspects of this type of soil have been in progress for decades. However, considerable natural variability in physical properties of in-situ loess strata even in a single block sample challenges the fundamental laboratory investigations. The reason behind this is that it is somehow impossible to remove the effect of a specific factor like void ratio from fair comparisons to come with a reliable conclusion. In order to cope with this limitation, two types of artificially made dispersive and calcareous loess are introduced which can be easily reproduced in any soil mechanics laboratory provided that all its compositions are known and controlled. The collapse potential is explored for a variety of soil water salinity and lime content and comparisons are made against the natural soil behavior. Trends are reported for the influence of pore water salinity on collapse potential under different osmotic flow conditions. The most important advantage of artificial loess is the ease of controlling cementing agent content like calcite or dispersive potential for studying their influence on mechanical soil behavior.

Keywords: Artificial loess, unsaturated soils, collapse potential, dispersive clays, laboratory tests.

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70 E-Learning Management Systems General Framework

Authors: Hamed Fawareh

Abstract:

The recent development in learning technologies leads to emerge many learning management systems (LMS). In this study, we concentrate on the specifications and characteristics of LMSs. Furthermore, this paper emphasizes on the feature of e-learning management systems. The features take on the account main indicators to assist and evaluate the quality of e-learning systems. The proposed indicators based of ten dimensions.

Keywords: E-Learning, System Requirement, Social Requirement, Learning Management System.

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69 A Programming Solution for Moving Mobile Transaction

Authors: Osman Mohammed Hegazy, Ali Hamed El Bastawissy, Romani Farid Ibrahim

Abstract:

In this paper, our concern is the management of mobile transactions in the shared area among many servers, when the mobile user moves from one cell to another in online partiallyreplicated distributed mobile database environment. We defined the concept of transaction and classified the different types of transactions. Based on this analysis, we propose an algorithm that handles the disconnection due to moving among sites.

Keywords: Concurrency, mobile database, transaction processing, two phase locking.

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68 Order Penetration Point Location using Fuzzy Quadratic Programming

Authors: Hamed Rafiei, Masoud Rabbani

Abstract:

This paper addresses one of the most important issues have been considered in hybrid MTS/MTO production environments. To cope with the problem, a mathematical programming model is applied from a tactical point of view. The model is converted to a fuzzy goal programming model, because a degree of uncertainty is involved in hybrid MTS/MTO context. Finally, application of the proposed model in an industrial center is reported and the results prove the validity of the model.

Keywords: Fuzzy sets theory, Hybrid MTS/MTO, Order penetration point, Quadratic programming.

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67 Detecting Circles in Image Using Statistical Image Analysis

Authors: Fathi M. O. Hamed, Salma F. Elkofhaifee

Abstract:

The aim of this work is to detect geometrical shape objects in an image. In this paper, the object is considered to be as a circle shape. The identification requires find three characteristics, which are number, size, and location of the object. To achieve the goal of this work, this paper presents an algorithm that combines from some of statistical approaches and image analysis techniques. This algorithm has been implemented to arrive at the major objectives in this paper. The algorithm has been evaluated by using simulated data, and yields good results, and then it has been applied to real data.

Keywords: Image processing, median filter, projection, scalespace, segmentation, threshold.

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66 Software Digital Phase-locked Loop for Induction Motor Speed Control

Authors: Benmabrouk. Zaineb, Ben Hamed. Mouna, Lassad. Sbita

Abstract:

This article deals to describe the simulation investigation of the digital phase locked loop implemented in software (SDPLL). SDPLL has been developed for speed drives of an induction motor in scalar strategy. A drive was implemented and simulation results are presented to verify the robustness against motor parameter variation and regulation speed.

Keywords: Induction motor, Software Digital Phase LockedLoop, Speed control, Simulation.

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65 Influence of Various Factors on Stability of CoSPc in LPG Sweetening Process

Authors: Ali Samadi Afshar, Hamed Harrafi, S.M.Javad Gharib Zahedi

Abstract:

IFP Group Technology “Sulfrex process" was used in Iran-s South Pars Gas Complex Refineries for removing sulfur compounds such as mercaptans, carbonyl sulfide and hydrogen sulfide, which uses sulfonated cobalt phthalocyanine dispersed in alkaline solution as catalyst. In this technology, catalyst and alkaline solution were used circularly. However the stability of catalyst due to effect of some parameters would reduce with the running of the unit and therefore sweetening efficiency would be decreased. Hence, the aim of this research is study the factors effecting on the stability of catalyst.

Keywords: sulfonated cobalt phthalocyanine, mercaptans, stability, catalyst, sulfur.

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64 A Parallel Quadtree Approach for Image Compression using Wavelets

Authors: Hamed Vahdat Nejad, Hossein Deldari

Abstract:

Wavelet transforms are multiresolution decompositions that can be used to analyze signals and images. Image compression is one of major applications of wavelet transforms in image processing. It is considered as one of the most powerful methods that provides a high compression ratio. However, its implementation is very time-consuming. At the other hand, parallel computing technologies are an efficient method for image compression using wavelets. In this paper, we propose a parallel wavelet compression algorithm based on quadtrees. We implement the algorithm using MatlabMPI (a parallel, message passing version of Matlab), and compute its isoefficiency function, and show that it is scalable. Our experimental results confirm the efficiency of the algorithm also.

Keywords: Image compression, MPI, Parallel computing, Wavelets.

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63 Adjusting the Furnace and Converter Temperature of the Sulfur Recovery Units

Authors: Hamid Reza Mahdipoor, Hamid Ganji, Hamed Naderi, Hajar Yousefian, Hooman Javaherizadeh

Abstract:

The modified Claus process is commonly used in oil refining and gas processing to recover sulfur and destroy contaminants formed in upstream processing. A Claus furnace feed containing a relatively low concentration of H2S may be incapable of producing a stable flame. Also, incomplete combustion of hydrocarbons in the feed can lead to deterioration of the catalyst in the reactors due to soot or carbon deposition. Therefore, special consideration is necessary to achieve the appropriate overall sulfur recovery. In this paper, some configurations available to treat lean acid gas streams are described and the most appropriate ones are studied to overcome low H2S concentration problems. As a result, overall sulfur recovery is investigated for feed preheating and hot gas configurations.

Keywords: Sulfur recovery unit, Low H2S content

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62 Wireless Control for an Induction Motor

Authors: Benmabrouk. Zaineb, Ben Hamed. Mouna, Lassaad. Sbita

Abstract:

This paper discusses the development of wireless structure control of an induction motor scalar drives. This was realised up on the wireless WiFi networks. This strategy of control is ensured by the use of Wireless ad hoc networks and a virtual network interface based on VNC which is used to make possible to take the remote control of a PC connected on a wireless Ethernet network. Verification of the proposed strategy of control is provided by experimental realistic tests on scalar controlled induction motor drives. The experimental results of the implementations with their analysis are detailed.

Keywords: Digital drives, Induction motor, Remote control, Virtual Network Computing VNC, Wireless Local Area NetworkWiFi.

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61 Fermentative Production of Dextran using Food Industry Wastes

Authors: Marzieh Moosavi-Nasab, Mohsen Gavahian, Ali R. Yousefi, Hamed Askari

Abstract:

Dextran is a D-glucose polymer which is produced by Leuconostoc mesenteroides grown in a sucrose-rich media. The organism was obtained from the Persian Type Culture Collection (PTCC) and was transferred in MRS broth medium at 30°C and pH 6.8 for 24 h. After preparation of inoculums, organisms were inoculated into five liquid fermentation media containing either molasses or cheese whey or different combinations of cheese whey and molasses. After certain fermentation period, the produced dextran was separated and dried. Dextran yield was calculated and significant differences in different media were observed. Furthermore, FT-IR analysis was performed and the results showed that there were no significant differences in the produced dextran structures.

Keywords: Dextran, Leuconostoc mesenteroides, Molasses, Whey

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60 A Methodology for Reducing the BGP Convergence Time

Authors: Eatedal A. Alabdulkreem, Hamed S. Al-Raweshidy, Maysam F. Abbod

Abstract:

Border Gateway Protocol (BGP) is the standard routing protocol between various autonomous systems (AS) in the internet. In the event of failure, a considerable delay in the BGP convergence has been shown by empirical measurements. During the convergence time the BGP will repeatedly advertise new routes to some destination and withdraw old ones until it reach a stable state. It has been found that the KEEPALIVE message timer and the HOLD time are tow parameters affecting the convergence speed. This paper aims to find the optimum value for the KEEPALIVE timer and the HOLD time that maximally reduces the convergence time without increasing the traffic. The KEEPALIVE message timer optimal value founded by this paper is 30 second instead of 60 seconds, and the optimal value for the HOLD time is 90 seconds instead of 180 seconds.

Keywords: BGP, Convergence Time, HOLD time, Keep alive.

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59 Effects of Molybdenum on Phosphorus Concentration in Rice (Oryza sativa L.)

Authors: Hamed Zakikhani, Mohd Khanif Yusop, Amin Soltangheisi

Abstract:

A hydroponic trial was carried out to investigate the effect of molybdenum (Mo) on uptake of phosphorus (P) in different rice cultivars. The experiment was conducted using a randomized complete-block design, with a split-plot arrangement of treatments and three replications. Four rates of Mo (0, 0.01, 0.1 and 1 mg L−1) and five cultivars (MR219, HASHEMI, MR232, FAJRE and MR253) provided the main and sub-plots, respectively. Interaction of molybdenum×variety was significant on shoot phosphorus uptake (p≤0.01). Highest and lowest shoot phosphorus uptake were seen in Mo3V3 (0.6% plant-1) and Mo0V3 (0.14% plant-1) treatments, respectively. Molybdenum did not have a significant effect on root phosphorus content. According to results, application of molybdenum has a synergistic effect on uptake of phosphorus by rice plants.

Keywords: Molybdenum, Phosphorus, Uptake, rice.

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58 Identification and Classification of Plastic Resins using Near Infrared Reflectance Spectroscopy

Authors: Hamed Masoumi, Seyed Mohsen Safavi, Zahra Khani

Abstract:

In this paper, an automated system is presented for identification and separation of plastic resins based on near infrared (NIR) reflectance spectroscopy. For identification and separation among resins, a "Two-Filter" identification method is proposed that is capable to distinguish among polyethylene terephthalate (PET), high density polyethylene (HDPE), polyvinyl chloride (PVC), polypropylene (PP) and polystyrene (PS). Through surveying effects of parameters such as surface contamination, sample thickness, label and cap existence, it was obvious that the "Two-Filter" method has a high efficiency in identification of resins. It is shown that accurate identification and separation of five major resins can be obtained through calculating the relative reflectance at two wavelengths in the NIR region.

Keywords: Identification, Near Infrared, Plastic, Separation, Spectroscopy

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57 A High Quality Factor Filter Based on Quasi-Periodic Photonic Structure

Authors: Hamed Alipour-Banaei, Farhad Mehdizadeh

Abstract:

We report the design and characterization of ultra high quality factor filter based on one-dimensional photonic-crystal Thue- Morse sequence structure. The behavior of aperiodic array of photonic crystal structure is numerically investigated and we show that by changing the angle of incident wave, desired wavelengths could be tuned and a tunable filter is realized. Also it is shown that high quality factor filter be achieved in the telecommunication window around 1550 nm, with a device based on Thue-Morse structure. Simulation results show that the proposed structure has a quality factor more than 100000 and it is suitable for DWDM communication applications.

Keywords: Thue-Morse, filter, quality factor.

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56 Extension of a Smart Piezoelectric Ceramic Rod

Authors: Ali Reza Pouladkhan, Jalil Emadi, Hamed Habibolahiyan

Abstract:

This paper presents an exact solution and a finite element method (FEM) for a Piezoceramic Rod under static load. The cylindrical rod is made from polarized ceramics (piezoceramics) with axial poling. The lateral surface of the rod is traction-free and is unelectroded. The two end faces are under a uniform normal traction. Electrically, the two end faces are electroded with a circuit between the electrodes, which can be switched on or off. Two cases of open and shorted electrodes (short circuit and open circuit) will be considered. Finally, a finite element model will be used to compare the results with an exact solution. The study uses ABAQUS (v.6.7) software to derive the finite element model of the ceramic rod.

Keywords: Finite element method, Ceramic rod; Axial poling, Normal traction, Short circuit, Open circuit.

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55 Investigation of Solvent Effect on Viscosity of Lubricant in Disposable Medical Devices

Authors: Hamed Bagheri, Seyd Javid Shariati

Abstract:

The effects of type and amount of solvent on lubricant which is used in disposable medical devices are investigated in this article. Two kinds of common solvent, n-Hexane and n-Heptane, are used. The mechanical behavior of syringe has shown that n-Heptane has better mixing ratio and also more effective spray process in the barrel of syringe than n-Hexane because of similar solubility parameter to silicon oil. The results revealed that movement of plunger in the barrel increases when pure silicone is used because non-uniform film is created on the surface of barrel, and also, it seems that the form of silicon is converted from oil to gel due to sterilization process. The results showed that the convenient mixing ratio of solvent/lubricant oil is 80/20.

Keywords: Disposable medical devices, lubricant oil, solvent effect, solubility parameter.

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54 Application New Approach with Two Networks Slow and Fast on the Asynchronous Machine

Authors: Samia Salah, M’hamed Hadj Sadok, Abderrezak Guessoum

Abstract:

In this paper, we propose a new modular approach called neuroglial consisting of two neural networks slow and fast which emulates a biological reality recently discovered. The implementation is based on complex multi-time scale systems; validation is performed on the model of the asynchronous machine. We applied the geometric approach based on the Gerschgorin circles for the decoupling of fast and slow variables, and the method of singular perturbations for the development of reductions models.

This new architecture allows for smaller networks with less complexity and better performance in terms of mean square error and convergence than the single network model.

Keywords: Gerschgorin’s Circles, Neuroglial Network, Multi time scales systems, Singular perturbation method.

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53 Web Usability : A Fuzzy Approach to the Navigation Structure Enhancement in a Website System, Case of Iranian Civil Aviation Organization Website

Authors: Hamed Qahri Saremi, Gholam Ali Montazer

Abstract:

With the proliferation of World Wide Web, development of web-based technologies and the growth in web content, the structure of a website becomes more complex and web navigation becomes a critical issue to both web designers and users. In this paper we define the content and web pages as two important and influential factors in website navigation and paraphrase the enhancement in the website navigation as making some useful changes in the link structure of the website based on the aforementioned factors. Then we suggest a new method for proposing the changes using fuzzy approach to optimize the website architecture. Applying the proposed method to a real case of Iranian Civil Aviation Organization (CAO) website, we discuss the results of the novel approach at the final section.

Keywords: Web content, Web navigation, Website system, Webusage mining.

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52 Improving Cache Memory Utilization

Authors: Sami I. Serhan, Hamed M. Abdel-Haq

Abstract:

In this paper, an efficient technique is proposed to manage the cache memory. The proposed technique introduces some modifications on the well-known set associative mapping technique. This modification requires a little alteration in the structure of the cache memory and on the way by which it can be referenced. The proposed alteration leads to increase the set size virtually and consequently to improve the performance and the utilization of the cache memory. The current mapping techniques have accomplished good results. In fact, there are still different cases in which cache memory lines are left empty and not used, whereas two or more processes overwrite the lines of each other, instead of using those empty lines. The proposed algorithm aims at finding an efficient way to deal with such problem.

Keywords: Modified Set Associative Mapping, Locality of Reference, Miss Ratio, Hit Ratio, Cache Memory, Clustered Behavior, Index Address, Tag Field, Status Field, and Complement of Index Address.

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51 [Ti(OC4H9)4/2,5-Dimethoxytetrahydrofuran/ TEA/Ethylene Chlorobromide] as a Novel Homogeneous Catalyst System Effective for the Ethylene Dimerization Reaction

Authors: Seyed Hamed Mahdaviani, Davood Soudbar, Matin Parvari

Abstract:

In the present research, the titanium-catalyzed ethylene dimerization and more specifically, the concomitant byproducts and polymer formation have been studied in the presence of 2,5-dimethoxytetrahydrofuran as an electron donor compound in the combination with triethylaluminium (TEA) as activator. Then, we added ethylene chlorobromide as a new efficient promoter to the relevant catalyst system. Finally, the behavior of novel homogeneous [Titanium tetrabutoxide (Ti(OC4H9)4)/2,5-dimethoxytetrahydrofuran/ TEA/ethylene chlorobromide] was investigated in the various operating conditions for the optimum production of 1-butene. In the optimum conditions, a very high ethylene conversion (almost 90.77 %), a relative high selectivity to 1-butene (79.00 %), yield of reaction equal to 71.70 % and a significant productivity (turnover frequency equal to 1370 h-1) were achieved.

Keywords: Ethylene dimerization, 2, 5-dimethoxytetrahydrofuran, ethylene chlorobromide, polymeric compounds

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50 Optimal Policy for a Deteriorating Inventory Model with Finite Replenishment Rate and with Price Dependant Demand Rate and Cycle Length Dependant Price

Authors: Hamed Sabahno

Abstract:

In this paper, an inventory model with finite and constant replenishment rate, price dependant demand rate, time value of money and inflation, finite time horizon, lead time and exponential deterioration rate and with the objective of maximizing the present worth of the total system profit is developed. Using a dynamic programming based solution algorithm, the optimal sequence of the cycles can be found and also different optimal selling prices, optimal order quantities and optimal maximum inventories can be obtained for the cycles with unequal lengths, which have never been done before for this model. Also, a numerical example is used to show accuracy of the solution procedure.

Keywords: Deteriorating items, Dynamic programming, Finitereplenishment rate, Inventory control, Operation Research.

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49 Vibration Analysis of the Gas Turbine Considering Dependency of Stiffness and Damping on Frequency

Authors: Hamed Jamshidi, Pooya Djamshidi

Abstract:

In this paper the complete rotor system including elastic shaft with distributed mass, allowing for the effects of oil film in bearings. Also, flexibility of foundation is modeled. As a whole this article is a relatively complete research in modeling and vibration analysis of rotor considering gyroscopic effect, damping, dependency of stiffness and damping coefficients on frequency and solving the vibration equations including these parameters. On the basis of finite element method and utilizing four element types including element of shaft, disk, bearing and foundation and using MATLAB, a computer program is written. So the responses in several cases and considering different effects are obtained. Then the results are compared with each other, with exact solutions and results of other papers.

Keywords: Damping coefficients , Finite element method, Modeling , Rotor vibration

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48 Improved Hill Climbing and Simulated Annealing Algorithms for Size Optimization of Trusses

Authors: Morteza Kazemi Torbaghan, Seyed Mehran Kazemi, Rahele Zhiani, Fakhriye Hamed

Abstract:

Truss optimization problem has been vastly studied during the past 30 years and many different methods have been proposed for this problem. Even though most of these methods assume that the design variables are continuously valued, in reality, the design variables of optimization problems such as cross-sectional areas are discretely valued. In this paper, an improved hill climbing and an improved simulated annealing algorithm have been proposed to solve the truss optimization problem with discrete values for crosssectional areas. Obtained results have been compared to other methods in the literature and the comparison represents that the proposed methods can be used more efficiently than other proposed methods

Keywords: Size Optimization of Trusses, Hill Climbing, Simulated Annealing.

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47 A Novel Fuzzy Technique for Image Noise Reduction

Authors: Hamed Vahdat Nejad, Hameed Reza Pourreza, Hasan Ebrahimi

Abstract:

A new fuzzy filter is presented for noise reduction of images corrupted with additive noise. The filter consists of two stages. In the first stage, all the pixels of image are processed for determining noisy pixels. For this, a fuzzy rule based system associates a degree to each pixel. The degree of a pixel is a real number in the range [0,1], which denotes a probability that the pixel is not considered as a noisy pixel. In the second stage, another fuzzy rule based system is employed. It uses the output of the previous fuzzy system to perform fuzzy smoothing by weighting the contributions of neighboring pixel values. Experimental results are obtained to show the feasibility of the proposed filter. These results are also compared to other filters by numerical measure and visual inspection.

Keywords: Additive noise, Fuzzy logic, Image processing, Noise reduction.

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46 Playing Games with Genetic Algorithms: Application on Price-QoS Competition in Telecommunications Market

Authors: M’hamed Outanoute, Mohamed Baslam, Belaid Bouikhalene

Abstract:

The customers use the best compromise criterion between price and quality of service (QoS) to select or change their Service Provider (SP). The SPs share the same market and are competing to attract more customers to gain more profit. Due to the divergence of SPs interests, we believe that this situation is a non-cooperative game of price and QoS. The game converges to an equilibrium position known Nash Equilibrium (NE). In this work, we formulate a game theoretic framework for the dynamical behaviors of SPs. We use Genetic Algorithms (GAs) to find the price and QoS strategies that maximize the profit for each SP and illustrate the corresponding strategy in NE. In order to quantify how this NE point is performant, we perform a detailed analysis of the price of anarchy induced by the NE solution. Finally, we provide an extensive numerical study to point out the importance of considering price and QoS as a joint decision parameter.

Keywords: Pricing, QoS, Market share game, Genetic algorithms, Nash equilibrium, Learning, Price of anarchy.

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45 Changes of in vitro Cytokine Production induced by δ-Lactams

Authors: Y. Baba hamed, A. Medjdoub, H. Merzouk, M. Narce

Abstract:

The aim of this work was to study the in vitro effects of δ-lactam 1 and its 4-chlorophenyl derivative 2, on the proliferative responses of human lymphocytes and Th1 and Th2 cytokine secretion. The possible protective role of vitamin E on intracellular stress oxidative induced by these compounds was also investigated. Peripheral blood lymphocytes were isolated using differential centrifugation on a density gradient of Histopaque. They were cultured with mitogen concanavalin A, vitamin E (10 μM) and with different concentrations of the compounds 1 and 2 (0.1 to 10 μM). Proliferation (MTT assay), IL-2, INFγ and IL-4 (Elisa kits), intracellular superoxide anion were determined. 1 and 2 were immunostimulant and increased cytokine secretion with a shift away from Th1 response to Th2. These properties were however accompanied by an increase in intracellular oxidative stress. The presence of vitamin E exhibited protective effects by reducing δ- lactam-induced superoxide anion generation in lymphocytes.

Keywords: Cytokines, δ-Lactams, In vitro Lymphocyte Proliferation, Superoxide Anion

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