Search results for: Ultrasensitive detection in blood
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 1851

Search results for: Ultrasensitive detection in blood

1371 Shunt Power Active Filter Control under NonIdeal Voltages Conditions

Authors: H. Abaali, M. T. Lamchich, M. Raoufi

Abstract:

In this paper, we propose the Modified Synchronous Detection (MSD) Method for determining the reference compensating currents of the shunt active power filter under non sinusoidal voltages conditions. For controlling the inverter switching we used the PI regulator. The numerical simulation results, using Power System Blockset Toolbox PSB of Matlab, from a complete structure, are presented and discussed.

Keywords: Distorted, harmonic, Modified Synchronous Detection Method, PI regulator, Shunt Active Power Filter, unbalanced.

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1370 Fault Detection of Drinking Water Treatment Process Using PCA and Hotelling's T2 Chart

Authors: Joval P George, Dr. Zheng Chen, Philip Shaw

Abstract:

This paper deals with the application of Principal Component Analysis (PCA) and the Hotelling-s T2 Chart, using data collected from a drinking water treatment process. PCA is applied primarily for the dimensional reduction of the collected data. The Hotelling-s T2 control chart was used for the fault detection of the process. The data was taken from a United Utilities Multistage Water Treatment Works downloaded from an Integrated Program Management (IPM) dashboard system. The analysis of the results show that Multivariate Statistical Process Control (MSPC) techniques such as PCA, and control charts such as Hotelling-s T2, can be effectively applied for the early fault detection of continuous multivariable processes such as Drinking Water Treatment. The software package SIMCA-P was used to develop the MSPC models and Hotelling-s T2 Chart from the collected data.

Keywords: Principal component analysis, hotelling's t2 chart, multivariate statistical process control, drinking water treatment.

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1369 Design of an Ensemble Learning Behavior Anomaly Detection Framework

Authors: Abdoulaye Diop, Nahid Emad, Thierry Winter, Mohamed Hilia

Abstract:

Data assets protection is a crucial issue in the cybersecurity field. Companies use logical access control tools to vault their information assets and protect them against external threats, but they lack solutions to counter insider threats. Nowadays, insider threats are the most significant concern of security analysts. They are mainly individuals with legitimate access to companies information systems, which use their rights with malicious intents. In several fields, behavior anomaly detection is the method used by cyber specialists to counter the threats of user malicious activities effectively. In this paper, we present the step toward the construction of a user and entity behavior analysis framework by proposing a behavior anomaly detection model. This model combines machine learning classification techniques and graph-based methods, relying on linear algebra and parallel computing techniques. We show the utility of an ensemble learning approach in this context. We present some detection methods tests results on an representative access control dataset. The use of some explored classifiers gives results up to 99% of accuracy.

Keywords: Cybersecurity, data protection, access control, insider threat, user behavior analysis, ensemble learning, high performance computing.

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1368 Nutritional Composition of Crackers Produced from Blend of Sprouted Pigeon Pea (Cajanus cajan), Unripe Plantain (Musa parasidiaca) and Brewers’ Spent Grain Flour and Blood Glucose Level of Diabetic Rats Fed the Biscuit

Authors: Nneka N. Uchegbu, Charles N. Ishiwu

Abstract:

The nutritional composition and hypoglycaemic effect of crackers produced from blend of sprouted pigeon pea, unripe plantain and brewers’ spent grain and fed to Alloxan induced diabetic rat was investigated. Crackers were produced from different blends of sprouted pigeon pea, unripe plantain and brewers’ spent grain. The crackers were evaluated for proximate composition, amino acid profile and antinutritional factors. Blood glucose levels of normal and diabetic rats fed with the control sample and different formulations of cracker were measured. The protein content of the samples were significantly different (p<0.05) from each other with sample A having the lowest value and sample B with the highest value. The values obtained showed that the samples contained most of the amino acids that are found in plant proteins. The levels of antinutritional factor determined were generally low. Administration of the formulated cracker meals led to a significant reduction in the fasting blood glucose level in the diabetic rats. The present study concluded that consumption of crackers produced from this composite flour could be recommended for the diabetics and those who are sceptical about the disease.

Keywords: Crackers, diabetics rat, sprouted pigeon pea, unripe plantain and brewers’ spent grain.

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1367 Optimization the Conditions of Electrophoretic Deposition Fabrication of Graphene-Based Electrode to Consider Applications in Electro-Optical Sensors

Authors: Sepehr Lajevardi Esfahani, Shohre Rouhani, Zahra Ranjbar

Abstract:

Graphene has gained much attention owing to its unique optical and electrical properties. Charge carriers in graphene sheets (GS) carry out a linear dispersion relation near the Fermi energy and behave as massless Dirac fermions resulting in unusual attributes such as the quantum Hall effect and ambipolar electric field effect. It also exhibits nondispersive transport characteristics with an extremely high electron mobility (15000 cm2/(Vs)) at room temperature. Recently, several progresses have been achieved in the fabrication of single- or multilayer GS for functional device applications in the fields of optoelectronic such as field-effect transistors ultrasensitive sensors and organic photovoltaic cells. In addition to device applications, graphene also can serve as reinforcement to enhance mechanical, thermal, or electrical properties of composite materials. Electrophoretic deposition (EPD) is an attractive method for development of various coatings and films. It readily applied to any powdered solid that forms a stable suspension. The deposition parameters were controlled in various thicknesses. In this study, the graphene electrodeposition conditions were optimized. The results were obtained from SEM, Ohm resistance measuring technique and AFM characteristic tests. The minimum sheet resistance of electrodeposited reduced graphene oxide layers is achieved at conditions of 2 V in 10 s and it is annealed at 200 °C for 1 minute.

Keywords: Electrophoretic deposition, graphene oxide, electrical conductivity, electro-optical devices.

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1366 Evaluation of Edge Configuration in Medical Echo Images Using Genetic Algorithms

Authors: Ching-Fen Jiang

Abstract:

Edge detection is usually the first step in medical image processing. However, the difficulty increases when a conventional kernel-based edge detector is applied to ultrasonic images with a textural pattern and speckle noise. We designed an adaptive diffusion filter to remove speckle noise while preserving the initial edges detected by using a Sobel edge detector. We also propose a genetic algorithm for edge selection to form complete boundaries of the detected entities. We designed two fitness functions to evaluate whether a criterion with a complex edge configuration can render a better result than a simple criterion such as the strength of gradient. The edges obtained by using a complex fitness function are thicker and more fragmented than those obtained by using a simple fitness function, suggesting that a complex edge selecting scheme is not necessary for good edge detection in medical ultrasonic images; instead, a proper noise-smoothing filter is the key.

Keywords: edge detection, ultrasonic images, speckle noise

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1365 A Reliable FPGA-based Real-time Optical-flow Estimation

Authors: M. M. Abutaleb, A. Hamdy, M. E. Abuelwafa, E. M. Saad

Abstract:

Optical flow is a research topic of interest for many years. It has, until recently, been largely inapplicable to real-time applications due to its computationally expensive nature. This paper presents a new reliable flow technique which is combined with a motion detection algorithm, from stationary camera image streams, to allow flow-based analyses of moving entities, such as rigidity, in real-time. The combination of the optical flow analysis with motion detection technique greatly reduces the expensive computation of flow vectors as compared with standard approaches, rendering the method to be applicable in real-time implementation. This paper describes also the hardware implementation of a proposed pipelined system to estimate the flow vectors from image sequences in real time. This design can process 768 x 576 images at a very high frame rate that reaches to 156 fps in a single low cost FPGA chip, which is adequate for most real-time vision applications.

Keywords: Optical flow, motion detection, real-time systems, FPGA.

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1364 On Leak Localization in the Main Branched and Simple Inclined Gas Pipelines

Authors: T. Davitashvili, G. Gubelidze

Abstract:

In this paper two mathematical models for definition of gas accidental escape localization in the gas pipelines are suggested. The first model was created for leak localization in the horizontal branched pipeline and second one for leak detection in inclined section of the main gas pipeline. The algorithm of leak localization in the branched pipeline did not demand on knowledge of corresponding initial hydraulic parameters at entrance and ending points of each sections of pipeline. For detection of the damaged section and then leak localization in this section special functions and equations have been constructed. Some results of calculations for compound pipelines having two, four and five sections are presented. Also a method and formula for the leak localization in the simple inclined section of the main gas pipeline are suggested. Some results of numerical calculations defining localization of gas escape for the inclined pipeline are presented.

Keywords: Branched and inclined gas pipelines, leak detection, mathematical modeling.

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1363 An Efficient Implementation of High Speed Vedic Multiplier Using Compressors for Image Processing Applications

Authors: Shobha Sharma, Amita Dev, Akanksha Kant

Abstract:

Digital signal processor, image signal processor and FIR filters have multipliers as an important part of their design. On the basis of Vedic mathematics, Vedic multipliers have come out to be very fast multipliers. One of the image processing applications is edge detection. This research presents a small area and high speed 8 bit Vedic multiplier system comprising of compressor based adders. This results in faster edge detection. This architecture is tested on Xilinx vertex 4 FPGA board and simulations were carried out using the Xilinx synthesis tool. Comparisons are made and this system is found to be smaller in area with high speed (the lesser propagation delay). This compressor based Vedic multiplier is 1.1 times speedier than a typical Vedic multiplier. Also, this Vedic Multiplier is 2 times speedier than a ‘simple’ multiplier.

Keywords: Detection of edges, Vedic multiplier, image processing, Urdhva Tiryakbhyam sutra.

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1362 Automatically Driven Vector for Guidewire Segmentation in 2D and Biplane Fluoroscopy

Authors: Simon Lessard, Pascal Bigras, Caroline Lau, Daniel Roy, Gilles Soulez, Jacques A. de Guise

Abstract:

The segmentation of endovascular tools in fluoroscopy images can be accurately performed automatically or by minimum user intervention, using known modern techniques. It has been proven in literature, but no clinical implementation exists so far because the computational time requirements of such technology have not yet been met. A classical segmentation scheme is composed of edge enhancement filtering, line detection, and segmentation. A new method is presented that consists of a vector that propagates in the image to track an edge as it advances. The filtering is performed progressively in the projected path of the vector, whose orientation allows for oriented edge detection, and a minimal image area is globally filtered. Such an algorithm is rapidly computed and can be implemented in real-time applications. It was tested on medical fluoroscopy images from an endovascular cerebral intervention. Ex- periments showed that the 2D tracking was limited to guidewires without intersection crosspoints, while the 3D implementation was able to cope with such planar difficulties.

Keywords: Edge detection, Line Enhancement, Segmentation, Fluoroscopy.

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1361 Various Information Obtained from Acoustic Emissions Owing to Discharges in XLPE Cable

Authors: Tatsuya Sakoda, Yuta Nakamura, Junichiro Kitajima, Masaki Sugiura, Satoshi Kurihara, Kenji Baba, Koichiro Kaneko, Takayoshi Yarimitsu

Abstract:

An acoustic emission (AE) technique is useful for detection of partial discharges (PDs) at a joint and a terminal section of a cross-linked polyethylene (XLPE) cable. For AE technique, it is not difficult to detect a PD using AE sensors. However, it is difficult to grasp whether the detected AE signal is owing to a single discharge or not. Additionally, when an AE technique is applied at a terminal section of a XLPE cable in salt pollution district, for example, there is possibility of detection of AE signals owing to creeping discharges on the surface of electric power apparatus. In this study, we evaluated AE signals in order to grasp what kind of information we can get from detected AE signals. The results showed that envelop detection of AE signal and a period which some AE signals were continuously detected were good indexes for estimating state-of-discharge.

Keywords: acoustic emission, creeping discharge, partial discharge, XLPE cable

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1360 Detection of Oxidative Stress Induced by Mobile Phone Radiation in Tissues of Mice using 8-Oxo-7, 8-Dihydro-2'-Deoxyguanosine as a Biomarker

Authors: Ahmad M. Khalil, Ahmad M. Alshamali, Marwan H. Gagaa

Abstract:

We investigated oxidative DNA damage caused by radio frequency radiation using 8-oxo-7, 8-dihydro-2'- deoxyguanosine (8-oxodG) generated in mice tissues after exposure to 900 MHz mobile phone radio frequency in three independent experiments. The RF was generated by a Global System for Mobile Communication (GSM) signal generator. The radio frequency field was adjusted to 25 V/m. The whole body specific absorption rate (SAR) was 1.0 W/kg. Animals were exposed to this field for 30 min daily for 30 days. 24 h post-exposure, blood serum, brain and spleen were removed and DNA was isolated. Enzyme-linked immunosorbent assay (ELISA) was used to measure 8-oxodG concentration. All animals survived the whole experimental period. The body weight of animals did not change significantly at the end of the experiment. No statistically significant differences observed in the levels of oxidative stress. Our results are not in favor of the hypothesis that 900 MHz RF induces oxidative damage.

Keywords: Mice, Mobile phone radiation, oxidative stress, 8-oxo-7, 8-dihydro-2'-deoxyguanosine

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1359 Ultra Wideband Breast Cancer Detection by Using SAR for Indication the Tumor Location

Authors: Wittawat Wasusathien, Samran Santalunai, Thanaset Thosdeekoraphat, Chanchai Thongsopa

Abstract:

This paper presents breast cancer detection by observing the specific absorption rate (SAR) intensity for identification tumor location, the tumor is identified in coordinates (x,y,z) system. We examined the frequency between 4-8 GHz to look for the most appropriate frequency. Results are simulated in frequency 4-8 GHz, the model overview include normal breast with 50 mm radian, 5 mm diameter of tumor, and ultra wideband (UWB) bowtie antenna. The models are created and simulated in CST Microwave Studio. For this simulation, we changed antenna to 5 location around the breast, the tumor can be detected when an antenna is close to the tumor location, which the coordinate of maximum SAR is approximated the tumor location. For reliable, we experiment by random tumor location to 3 position in the same size of tumor and simulation the result again by varying the antenna position in 5 position again, and it also detectable the tumor position from the antenna that nearby tumor position by maximum value of SAR, which it can be detected the tumor with precision in all frequency between 4-8 GHz.

Keywords: Specific absorption rate (SAR), ultra wideband (UWB), coordinates and cancer detection

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1358 Color Image Edge Detection using Pseudo-Complement and Matrix Operations

Authors: T. N. Janakiraman, P. V. S. S. R. Chandra Mouli

Abstract:

A color image edge detection algorithm is proposed in this paper using Pseudo-complement and matrix rotation operations. First, pseudo-complement method is applied on the image for each channel. Then, matrix operations are applied on the output image of the first stage. Dominant pixels are obtained by image differencing between the pseudo-complement image and the matrix operated image. Median filtering is carried out to smoothen the image thereby removing the isolated pixels. Finally, the dominant or core pixels occurring in at least two channels are selected. On plotting the selected edge pixels, the final edge map of the given color image is obtained. The algorithm is also tested in HSV and YCbCr color spaces. Experimental results on both synthetic and real world images show that the accuracy of the proposed method is comparable to other color edge detectors. All the proposed procedures can be applied to any image domain and runs in polynomial time.

Keywords: Color edge detection, dominant pixels, matrixrotation/shift operations, pseudo-complement.

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1357 Fuzzy Hyperbolization Image Enhancement and Artificial Neural Network for Anomaly Detection

Authors: Sri Hartati, 1Agus Harjoko, Brad G. Nickerson

Abstract:

A prototype of an anomaly detection system was developed to automate process of recognizing an anomaly of roentgen image by utilizing fuzzy histogram hyperbolization image enhancement and back propagation artificial neural network. The system consists of image acquisition, pre-processor, feature extractor, response selector and output. Fuzzy Histogram Hyperbolization is chosen to improve the quality of the roentgen image. The fuzzy histogram hyperbolization steps consist of fuzzyfication, modification of values of membership functions and defuzzyfication. Image features are extracted after the the quality of the image is improved. The extracted image features are input to the artificial neural network for detecting anomaly. The number of nodes in the proposed ANN layers was made small. Experimental results indicate that the fuzzy histogram hyperbolization method can be used to improve the quality of the image. The system is capable to detect the anomaly in the roentgen image.

Keywords: Image processing, artificial neural network, anomaly detection.

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1356 Detection of Sags, Swells, and Transients Using Windowing Technique Based On Continuous S-Transform (CST)

Authors: K. Daud, A. F. Abidin, N. Hamzah, H. S. Nagindar Singh

Abstract:

This paper produces a new approach for power quality analysis using a windowing technique based on Continuous S-transform (CST). This half-cycle window technique approach can detect almost correctly for initial detection of disturbances i.e. voltage sags, swells, and transients. Samples in half cycle window has been analyzed based continuous S-transform for entire disturbance waveform. The modified parameter has been produced by MATLAB programming m-file based on continuous s-transform. CST has better time frequency and localization property than traditional and also has ability to detect the disturbance under noisy condition correctly. The excellent time-frequency resolution characteristic of the CST makes it the most an attractive candidate for analysis of power system disturbances signals.

Keywords: Power quality disturbances, initial detection, half cycle windowing, continuous S-transform.

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1355 The Journey of a Malicious HTTP Request

Authors: M. Mansouri, P. Jaklitsch, E. Teiniker

Abstract:

SQL injection on web applications is a very popular kind of attack. There are mechanisms such as intrusion detection systems in order to detect this attack. These strategies often rely on techniques implemented at high layers of the application but do not consider the low level of system calls. The problem of only considering the high level perspective is that an attacker can circumvent the detection tools using certain techniques such as URL encoding. One technique currently used for detecting low-level attacks on privileged processes is the tracing of system calls. System calls act as a single gate to the Operating System (OS) kernel; they allow catching the critical data at an appropriate level of detail. Our basic assumption is that any type of application, be it a system service, utility program or Web application, “speaks” the language of system calls when having a conversation with the OS kernel. At this level we can see the actual attack while it is happening. We conduct an experiment in order to demonstrate the suitability of system call analysis for detecting SQL injection. We are able to detect the attack. Therefore we conclude that system calls are not only powerful in detecting low-level attacks but that they also enable us to detect highlevel attacks such as SQL injection.

Keywords: Linux system calls, Web attack detection, Interception.

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1354 Application of Java-based Pointcuts in Aspect Oriented Programming (AOP) for Data Race Detection

Authors: Sadaf Khalid, Fahim Arif

Abstract:

Wide applicability of concurrent programming practices in developing various software applications leads to different concurrency errors amongst which data race is the most important. Java provides greatest support for concurrent programming by introducing various concurrency packages. Aspect oriented programming (AOP) is modern programming paradigm facilitating the runtime interception of events of interest and can be effectively used to handle the concurrency problems. AspectJ being an aspect oriented extension to java facilitates the application of concepts of AOP for data race detection. Volatile variables are usually considered thread safe, but they can become the possible candidates of data races if non-atomic operations are performed concurrently upon them. Various data race detection algorithms have been proposed in the past but this issue of volatility and atomicity is still unaddressed. The aim of this research is to propose some suggestions for incorporating certain conditions for data race detection in java programs at the volatile fields by taking into account support for atomicity in java concurrency packages and making use of pointcuts. Two simple test programs will demonstrate the results of research. The results are verified on two different Java Development Kits (JDKs) for the purpose of comparison.

Keywords: Aspect Bench Compiler (abc), Aspect OrientedProgramming (AOP), AspectJ, Aspects, Concurrency packages, Concurrent programming, Cross-cutting Concerns, Data race, Eclipse, Java, Java Development Kits (JDKs), Pointcuts

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1353 A Detection Method of Faults in Railway Pantographs Based on Dynamic Phase Plots

Authors: G. Santamato, M. Solazzi, A. Frisoli

Abstract:

Systems for detection of damages in railway pantographs effectively reduce the cost of maintenance and improve time scheduling. In this paper, we present an approach to design a monitoring tool fitting strong customer requirements such as portability and ease of use. Pantograph has been modeled to estimate its dynamical properties, since no data are available. With the aim to focus on suspensions health, a two Degrees of Freedom (DOF) scheme has been adopted. Parameters have been calculated by means of analytical dynamics. A Finite Element Method (FEM) modal analysis verified the former model with an acceptable error. The detection strategy seeks phase-plots topology alteration, induced by defects. In order to test the suitability of the method, leakage in the dashpot was simulated on the lumped model. Results are interesting because changes in phase plots are more appreciable than frequency-shift. Further calculations as well as experimental tests will support future developments of this smart strategy.

Keywords: Pantograph models, phase-plots, structural health monitoring, vibration-based condition monitoring.

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1352 The Estimate Rate of Permanent Flow of a Liquid Simulating Blood by Doppler Effect

Authors: Malika.D Kedir-Talha, Mohammed Mehenni

Abstract:

To improve the characterization of blood flows, we propose a method which makes it possible to use the spectral analysis of the Doppler signals. Our calculation induces a reasonable approximation, the error made on estimated speed reflects the fact that speed depends on the flow conditions as well as on measurement parameters like the bore and the volume flow rate. The estimate of the Doppler signal frequency enables us to determine the maximum Doppler frequencie Fd max as well as the maximum flow speed. The results show that the difference between the estimated frequencies ( Fde ) and the Doppler frequencies ( Fd ) is small, this variation tends to zero for important θ angles and it is proportional to the diameter D. The description of the speed of friction and the coefficient of friction justify the error rate obtained.

Keywords: Doppler frequency, Doppler spectrum, estimate speed, permanent flow.

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1351 Image Spam Detection Using Color Features and K-Nearest Neighbor Classification

Authors: T. Kumaresan, S. Sanjushree, C. Palanisamy

Abstract:

Image spam is a kind of email spam where the spam text is embedded with an image. It is a new spamming technique being used by spammers to send their messages to bulk of internet users. Spam email has become a big problem in the lives of internet users, causing time consumption and economic losses. The main objective of this paper is to detect the image spam by using histogram properties of an image. Though there are many techniques to automatically detect and avoid this problem, spammers employing new tricks to bypass those techniques, as a result those techniques are inefficient to detect the spam mails. In this paper we have proposed a new method to detect the image spam. Here the image features are extracted by using RGB histogram, HSV histogram and combination of both RGB and HSV histogram. Based on the optimized image feature set classification is done by using k- Nearest Neighbor(k-NN) algorithm. Experimental result shows that our method has achieved better accuracy. From the result it is known that combination of RGB and HSV histogram with k-NN algorithm gives the best accuracy in spam detection.

Keywords: File Type, HSV Histogram, k-NN, RGB Histogram, Spam Detection.

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1350 Detecting Remote Protein Evolutionary Relationships via String Scoring Method

Authors: Nazar Zaki, Safaai Deris

Abstract:

The amount of the information being churned out by the field of biology has jumped manifold and now requires the extensive use of computer techniques for the management of this information. The predominance of biological information such as protein sequence similarity in the biological information sea is key information for detecting protein evolutionary relationship. Protein sequence similarity typically implies homology, which in turn may imply structural and functional similarities. In this work, we propose, a learning method for detecting remote protein homology. The proposed method uses a transformation that converts protein sequence into fixed-dimensional representative feature vectors. Each feature vector records the sensitivity of a protein sequence to a set of amino acids substrings generated from the protein sequences of interest. These features are then used in conjunction with support vector machines for the detection of the protein remote homology. The proposed method is tested and evaluated on two different benchmark protein datasets and it-s able to deliver improvements over most of the existing homology detection methods.

Keywords: Protein homology detection; support vectormachine; string kernel.

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1349 Fault Detection and Diagnosis of Broken Bar Problem in Induction Motors Base Wavelet Analysis and EMD Method: Case Study of Mobarakeh Steel Company in Iran

Authors: M. Ahmadi, M. Kafil, H. Ebrahimi

Abstract:

Nowadays, induction motors have a significant role in industries. Condition monitoring (CM) of this equipment has gained a remarkable importance during recent years due to huge production losses, substantial imposed costs and increases in vulnerability, risk, and uncertainty levels. Motor current signature analysis (MCSA) is one of the most important techniques in CM. This method can be used for rotor broken bars detection. Signal processing methods such as Fast Fourier transformation (FFT), Wavelet transformation and Empirical Mode Decomposition (EMD) are used for analyzing MCSA output data. In this study, these signal processing methods are used for broken bar problem detection of Mobarakeh steel company induction motors. Based on wavelet transformation method, an index for fault detection, CF, is introduced which is the variation of maximum to the mean of wavelet transformation coefficients. We find that, in the broken bar condition, the amount of CF factor is greater than the healthy condition. Based on EMD method, the energy of intrinsic mode functions (IMF) is calculated and finds that when motor bars become broken the energy of IMFs increases.

Keywords: Broken bar, condition monitoring, diagnostics, empirical mode decomposition, Fourier transform, wavelet transform.

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1348 Safety Study of Intravenously Administered Human Cord Blood Stem Cells in the Treatment of Symptoms Related to Chronic Inflammation

Authors: Brian M. Mehling, Louis Quartararo, Marine Manvelyan, Paul Wang, Dong-Cheng Wu

Abstract:

Numerous investigations suggest that Mesenchymal Stem Cells (MSCs) in general represent a valuable tool for therapy of symptoms related to chronic inflammatory diseases. Blue Horizon Stem Cell Therapy Program is a leading provider of adult and children’s stem cell therapies. Uniquely we have safely and efficiently treated more than 600 patients with documenting each procedure. The purpose of our study is primarily to monitor the immune response in order to validate the safety of intravenous infusion of human umbilical cord blood derived MSCs (UC-MSCs), and secondly, to evaluate effects on biomarkers associated with chronic inflammation. Nine patients were treated for conditions associated with chronic inflammation and for the purpose of antiaging. They have been given one intravenous infusion of UCMSCs. Our study of blood test markers of 9 patients with chronic inflammation before and within three months after MSCs treatment demonstrates that there is no significant changes and MSCs treatment was safe for the patients. Analysis of different indicators of chronic inflammation and aging included in initial, 24-hours, two weeks and three months protocols showed that stem cell treatment was safe for the patients; there were no adverse reactions. Moreover data from follow up protocols demonstrates significant improvement in energy level, hair, nails growth and skin conditions. Intravenously administered UC-MSCs were safe and effective in the improvement of symptoms related to chronic inflammation. Further close monitoring and inclusion of more patients are necessary to fully characterize the advantages of UC-MSCs application in treatment of symptoms related to chronic inflammation.

Keywords: Chronic inflammatory diseases, intravenous infusion, mesenchymal stem cells (MSCs), umbilical cord blood.

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1347 Efficient Detection Using Sequential Probability Ratio Test in Mobile Cognitive Radio Systems

Authors: Yeon-Jea Cho, Sang-Uk Park, Won-Chul Choi, Dong-Jo Park

Abstract:

This paper proposes a smart design strategy for a sequential detector to reliably detect the primary user-s signal, especially in fast fading environments. We study the computation of the log-likelihood ratio for coping with a fast changing received signal and noise sample variances, which are considered random variables. First, we analyze the detectability of the conventional generalized log-likelihood ratio (GLLR) scheme when considering fast changing statistics of unknown parameters caused by fast fading effects. Secondly, we propose an efficient sensing algorithm for performing the sequential probability ratio test in a robust and efficient manner when the channel statistics are unknown. Finally, the proposed scheme is compared to the conventional method with simulation results with respect to the average number of samples required to reach a detection decision.

Keywords: Cognitive radio, fast fading, sequential detection, spectrum sensing.

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1346 The Effects of Immersion on Visual Attention and Detection of Signals Performance for Virtual Reality Training Systems

Authors: Shiau-Feng Lin, Chiuhsiang Joe Lin, Rou-Wen Wang, Wei-Jung Shiang

Abstract:

The Virtual Reality (VR) is becoming increasingly important for business, education, and entertainment, therefore VR technology have been applied for training purposes in the areas of military, safety training and flying simulators. In particular, the superior and high reliability VR training system is very important in immersion. Manipulation training in immersive virtual environments is difficult partly because users must do without the hap contact with real objects they rely on in the real world to orient themselves and their manipulated. In this paper, we create a convincing questionnaire of immersion and an experiment to assess the influence of immersion on performance in VR training system. The Immersion Questionnaire (IQ) included spatial immersion, Psychological immersion, and Sensory immersion. We show that users with a training system complete visual attention and detection of signals. Twenty subjects were allocated to a factorial design consisting of two different VR systems (Desktop VR and Projector VR). The results indicated that different VR representation methods significantly affected the participants- Immersion dimensions.

Keywords: Virtual Reality, Training, Immersion, Visual Attention, Visual Detection

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1345 Development of a Brain Glutamate Microbiosensor

Authors: Kartika S. Hamdan, Zainiharyati M. Zain, Mohamed I. A. Halim, Jafri M. Abdullah, Robert D. O'Neill

Abstract:

This work attempts to improve the permselectivity of poly-ortho-phenylenediamine (PPD) coating for glutamate biosensor applications on Pt microelectrode, using constant potential amperometry and cyclic voltammetry. Percentage permeability of the modified PPD microelectrode was carried out towards hydrogen peroxide (H2O2) and ascorbic acid (AA) whereas permselectivity represents the percentage interference by AA in H2O2 detection. The 50-μm diameter Pt disk microelectrode showed a good permeability value toward H2O2 (95%) and selectivity against AA (0.01%) compared to other sizes of electrode studied here. The electrode was further modified with glutamate oxidase (GluOx) that was immobilized and cross linked with glutaraldehyde (GA, 0.125%), resulting in Pt/PPD/GluOx-GA electrode design. The maximum current density Jmax and apparent Michaelis constant, KM, obtained on Pt/PPD/GluOx-GA electrodes were 48 μA cm-2 and 50 μM, respectively. The linear region slope (LRS) was 0.96 μA cm-2 mM-1. The detection limit (LOD) for glutamate was 3.0 ± 0.6 μM. This study shows a promising glutamate microbiosensor for brain glutamate detection. 

Keywords: Brain, Glutamate, Microbiosensor.

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1344 From Electroencephalogram to Epileptic Seizures Detection by Using Artificial Neural Networks

Authors: Gaetano Zazzaro, Angelo Martone, Roberto V. Montaquila, Luigi Pavone

Abstract:

Seizure is the main factor that affects the quality of life of epileptic patients. The diagnosis of epilepsy, and hence the identification of epileptogenic zone, is commonly made by using continuous Electroencephalogram (EEG) signal monitoring. Seizure identification on EEG signals is made manually by epileptologists and this process is usually very long and error prone. The aim of this paper is to describe an automated method able to detect seizures in EEG signals, using knowledge discovery in database process and data mining methods and algorithms, which can support physicians during the seizure detection process. Our detection method is based on Artificial Neural Network classifier, trained by applying the multilayer perceptron algorithm, and by using a software application, called Training Builder that has been developed for the massive extraction of features from EEG signals. This tool is able to cover all the data preparation steps ranging from signal processing to data analysis techniques, including the sliding window paradigm, the dimensionality reduction algorithms, information theory, and feature selection measures. The final model shows excellent performances, reaching an accuracy of over 99% during tests on data of a single patient retrieved from a publicly available EEG dataset.

Keywords: Artificial Neural Network, Data Mining, Electroencephalogram, Epilepsy, Feature Extraction, Seizure Detection, Signal Processing.

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1343 People Counting in Transport Vehicles

Authors: Sebastien Harasse, Laurent Bonnaud, Michel Desvignes

Abstract:

Counting people from a video stream in a noisy environment is a challenging task. This project aims at developing a counting system for transport vehicles, integrated in a video surveillance product. This article presents a method for the detection and tracking of multiple faces in a video by using a model of first and second order local moments. An iterative process is used to estimate the position and shape of multiple faces in images, and to track them. the trajectories are then processed to count people entering and leaving the vehicle.

Keywords: face detection, tracking, counting, local statistics

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1342 The Effect of Body Condition Score on Hormonal and Vaginal Histological Changes During Estrus of Synchronized Etawah Cross Bred Does

Authors: Diah Tri Widayati, Sunendar, Kresno Suharto, Pudji Asuti, Aris Junaid

Abstract:

Eight Etawah cross bred does were divided into two groups based on body condition score (BCS). Group I (BSC 2, body weight 25-30 kg; n = 4), and Group II (BSC 3, body weight, 35-40 kg, n=4). All does received intravaginal controlled internal drug release devices (CIDR) for 10 days, and a prostaglandin F2α at 48 h before CIDR removal. Estrus detection was carried out using vasectomized buck. Vaginal epithelium was taken to determine estrus cycle. Blood samples were taken every 3-6 hours, started from moment of CIDR removal until the end of estrus. The results showed vaginal histological indicated estrus occurred at the hours of 25 to 60 and 30 to 70 post CIDR removal in BCS 2 and 3, respectively. Progesterone peak of BCS 2 and BCS 3 were 0.18±0.31 and 0.48±0.31 ng/mL on the hour 0 post CIDR removal. Estradiol -17ß peak of each group was 53.25±35.08 and 89.91±92.84 pg/mL at 48 post CIDR removal. LH surge only occurred on BCS 3 groups, the LH concentrations were 9.9± 9.1; 4.5± 4.0; and 18.2± 9.1 ng/mL at 45, 48 and 51 hours post CIDR removal, respectively. It was concluded that the BCS had effects on vaginal histological changes and LH surge.

Keywords: Estrus synchronization, Vaginal histological changes, Progesterone, Estradiol -17ß , LH

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