Search results for: Pressure Drop.

Authors: Chengli Liu, C. K. M. Lee

Abstract:

The tradition competitive newsvendor game assumes decision makers are rational. However, there are behavioral biases when people make decisions, such as loss aversion, mental accounting and overconfidence. Overestimation of a subject’s own performance is one type of overconfidence. The objective of this research is to analyze the impact of the overestimated demand in the newsvendor competitive game with two players. This study builds a competitive newsvendor game model where newsvendors have private information of their demands, which is overestimated. At the same time, demands of each newsvendor forecasted by a third party institution are available. This research shows that the overestimation leads to demand steal effect, which reduces the competitor’s order quantity. However, the overall supply of the product increases due to overestimation. This study illustrates the boundary condition for the overestimated newsvendor to have the equilibrium order drop due to the demand steal effect from the other newsvendor. A newsvendor who has higher critical fractile will see its equilibrium order decrease with the drop of estimation level from the other newsvendor.

Keywords: Bias, competitive newsvendor, Nash equilibrium, overestimation.

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Authors: Moiz S. Vohra, Nagalingam Arun Prasanth, Wei L. Tan, S. H. Yeo

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The understanding of generation and collapse of acoustic cavitation bubbles are prerequisites for application of cavitation erosion. Microbubbles generated due to rapid fluctuation of pressure induced by propagation of ultrasonic wave lead to formation of high velocity microjets and or shock waves upon collapse. Due to vast application of ultrasonic, it is important to characterize and understand cavitation collapse pressure under the radiating surface at different conditions. A comparative investigation is carried out to determine impact load and dynamic pressure distribution exerted upon bubble collapse using thin film pressure sensors. Measurements were recorded at different input conditions such as amplitude, stand-off distance, insertion depth of the horn inside the liquid and pulse on-off time of acoustic vibrations. Impact force of 2.97 N is recorded at amplitude of 108 μm and stand-off distance of 1 mm from the sensor film, whereas impulsive force as low as 0.4 N is recorded at amplitude of 12 μm and stand-off distance of 5 mm from the sensor film. The results drawn from the investigation indicated that variety of impact loads can be achieved by controlling generation and collapse of bubbles, making it suitable to use for numerous application.

Keywords: Ultrasonic cavitation, bubble collapse, pressure mapping sensor, impact load.

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Authors: Keshav Pujeri, Pranesh Jain, Krutibas Panda

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Significant changes in oil and gas drilling have emphasized the need to verify the integrity and reliability of drill stem components. Defects are inevitable in cast components, regardless of application; but if these defects go undetected, any severe defect could cause down-hole failure. One such defect is shrinkage porosity. Castings with lower level shrinkage porosity (CB levels 1 and 2) have scattered pores and do not occupy large volumes; so pressure testing and helium leak testing (HLT) are sufficient for qualifying the castings. However, castings with shrinkage porosity of CB level 3 and higher, behave erratically under pressure testing and HLT making these techniques insufficient for evaluating the castings- integrity. This paper presents a case study to highlight how the radiography technique is much more effective than pressure testing and HLT.

Keywords: Casting Defects, Interconnects, Leak Check, Pressure Test, Radiography.

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Authors: B. Navayineya, J. Vaseghi Amiri, M. Alijani Ardeshir

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Hydrodynamic pressures acting on upstream of concrete dams during an earthquake are an important factor in designing and assessing the safety of these structures in Earthquake regions. Due to inherent complexities, assessing exact hydrodynamic pressure is only feasible for problems with simple geometry. In this research, the governing equation of concrete gravity dam reservoirs with effect of fluid viscosity in frequency domain is solved and then compared with that in which viscosity is assumed zero. The results show that viscosity influences the reservoir-s natural frequency. In excitation frequencies near the reservoir's natural frequencies, hydrodynamic pressure has a considerable difference in compare to the results of non-viscose fluid.

Keywords: Closed form solution, concrete dams reservoir, viscosity, dynamic loads, hydrodynamic pressure.

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Authors: J. D. Burges, M. J. Hall, E. G. Lightsey

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A new dual-fluid concept was studied that could eventually find application for cold-gas propulsion for small space satellites or other constant flow applications. In basic form, the concept uses two different refrigerant working fluids, each having a different saturation vapor pressure. The higher vapor pressure refrigerant remains in the saturation phase and is used to pressurize the lower saturation vapor pressure fluid (the propellant) which remains in the compressed liquid phase. A demonstration thruster concept based on this principle was designed and built to study its operating characteristics. An automotive-type electronic fuel injector was used to meter and deliver the propellant. Ejected propellant mass and momentum were measured for several combinations of refrigerants and hydrocarbon fluids. The thruster has the advantage of delivering relatively large total impulse at low tank pressure within a small volume.

Keywords: cold-gas, nano-satellite, R134a, thruster

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Authors: C. Lanzerstorfer

Abstract:

Liquid sprays of water are frequently used in air pollution control for gas cooling purposes and for gas cleaning. Twin-fluid nozzles with internal mixing are often used for these purposes because of the small size of the drops produced. In these nozzles the liquid is dispersed by compressed air or another pressurized gas. In high efficiency scrubbers for particle separation, several nozzles are operated in parallel because of the size of the cross section. In such scrubbers, the scrubbing water has to be re-circulated. Precipitation of some solid material can occur in the liquid circuit, caused by chemical reactions. When such precipitations are detached from the place of formation, they can partly or totally block the liquid flow to a nozzle. Due to the resulting unbalanced supply of the nozzles with water and gas, the efficiency of separation decreases. Thus, the nozzles have to be cleaned if a certain fraction of blockages is reached. The aim of this study was to provide a tool for continuously monitoring the status of the nozzles of a scrubber based on the available operation data (water flow, air flow, water pressure and air pressure). The difference between the air pressure and the water pressure is not well suited for this purpose, because the difference is quite small and therefore very exact calibration of the pressure measurement would be required. Therefore, an equation for the reference air flow of a nozzle at the actual water flow and operation pressure was derived. This flow can be compared with the actual air flow for assessment of the status of the nozzles.

Keywords: Twin-fluid nozzles, operation data, condition monitoring, flow equation.

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Authors: Hoda Molavi, Sima Hoseinpoor, Hossein Bahmanyar

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A Rotary Disc Contactor with inner diameter of 9.1cm and maximum operating height of 40cm has been used to investigate break up phenomenon. Water-Toluene, Water as continuous phase and Toluene as dispersed phase, was selected as chemical system in the experiments. The mentioned chemical system has high interfacial tension so it was possible to form big drops which permit accurate investigation on break up phenomenon as well as the first and second critical rotor speeds. In this study, Break up phenomenon has been studied as a function of mother drop size, rotor speed and continuous phase height. Further more; the effects of mother drop size and continuous phase height on the first and second critical rotor speeds were investigated. Finally, two modified correlations were proposed to estimate the first and second critical speeds.

Keywords: Breakage, First critical rotor speed, Rotary disccontactor, Second critical rotor speed

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Authors: I. Struhár, L. Dovrtělová, M. Kumstát

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Regular exercise promotes reduction in blood pressure, reduction in body weight and it also helps to increase in insulin sensitivity. Participation in physical activity should always be linked to medical screening which can reveal serious medical problems. One of them is high blood pressure. Hypertension is risk factor for one billion people worldwide and the highest prevalence is found in Africa. Another component of hypertension is that people who suffer from hypertension have no symptoms. It is estimated that reduction of 3mm Hg in Systolic Blood Pressure decreases cardiac morbidity at least 5%. The most of the guidelines suggest aerobic exercise in a prevention of cardiovascular diseases. On the other hand, it is important to emphasize the impact of resistance training. Even, it was found higher effect for reduction on the level of systolic blood pressure than aerobic exercise.

Keywords: Coronary artery disease, physical activity, prevention, resistance training.

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Authors: Morteza Mirhosseini, Amir B. Khoshnevis

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The boundary layer separation and new active flow control of a NACA 0025 airfoil were studied experimentally. This new flow control is sometimes known as a co-flow jet (cfj) airfoil. This paper presents the fluctuating velocity in a wall jet over the co-flow jet airfoil subjected to an adverse pressure gradient and a curved surface. In these results, the fluctuating velocity at the inner part increasing by increased the angle of attack up to 12^o and this has due to the jet energized, while the angle of attack 20^o has different. The airfoil cord based Reynolds number has 10⁵.

Keywords: Adverse pressure gradient, fluctuating velocity, wall jet, co-flow jet airfoil.

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Authors: Tejeet Singh, Ishavneet Singh

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The present study focused on carrying out the creep analysis in an isotropic thick-walled composite cylindrical pressure vessel composed of aluminum matrix reinforced with silicon-carbide in particulate form. The creep behavior of the composite material has been described by the threshold stress based creep law. The values of stress exponent appearing in the creep law were selected as 3, 5 and 8. The constitutive equations were developed using well known von-Mises yield criteria. Models were developed to find out the distributions of creep stress and strain rate in thick-walled composite cylindrical pressure vessels under internal pressure. In order to obtain the stress distributions in the cylinder, the equilibrium equation of the continuum mechanics and the constitutive equations are solved together. It was observed that the radial stress, tangential stress and axial stress increases along with the radial distance. The cross-over was also obtained almost at the middle region of cylindrical vessel for tangential and axial stress for different values of stress exponent. The strain rates were also decreasing in nature along the entire radius.

Keywords: Steady state creep, composite, cylinder, pressure.

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Authors: Minh Tuan, Nguyen, Chung –Ruey, Yen

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The study was performed to evaluate the effect of Sgirdling, fruit thinning plus bagging with 2,4-D application, fruit thinning plus bagging on growth and quality of wax apple fruit. Girdling was applied three week before flowering. The 2,4-D was sprayed at the small bud and petal fall stage. The effect of all treatments on fruit growth was measured weekly. The physical and biochemical quality characteristics of the fruits were recorded. The results showed that no significant effect on number of bud among treatments. S-girdling, 2,4-D application produced the lowest bud drop, fruit drop compared to untreated control. Moreover, S-girdling enhanced faster fruit growth producing the best final fruit length and diameter than the control treatment. It was also observed that Sgirdling greatly increased fruit set, fruit weight as well as total soluble solid, reduced fruit crack, and titratable acidity. In conclusion, S-girdling had a distinctive and significant effect on most of the fruit quality characteristics assessed. Application 2,4-D was also recommended as the industry norm to increase fruit set, and fruit quality in wax apple.

Keywords: Wax apple, S-girdling, 2, 4-D, fruit bagging, fruit thinning.

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Authors: Bahar Razavi, Mansour Parehkar, Ali Gholami

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Pore water pressure is normally because of consolidation, compaction and water level fluctuation on reservoir. Measuring, controlling and analyzing of pore water pressure have significant importance in both of construction and operation period. Since end of 2002, (dam start up) nature of KARKHEH dam has been analyzed by using the gathered information from instrumentation system of dam. In this lecture dam condition after start up have been analyzed by using the gathered data from located piezometers in core of dam. According to TERZAGHI equation and records of piezometers, consolidation lasted around five years during early years of construction stage, and current pore water pressure in core of dam is caused by water level fluctuation in reservoir. Although there is time lag between water level fluctuation and results of piezometers. These time lags have been checked and the results clearly show that one of the most important causes of it is distance between piezometer and reservoir.

Keywords: Earth dam, Reservoir, Piezometer, Terzaghi, Consolidation

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Authors: S. Venkateswaran, C. Mallika Parveen

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The fluid flow and the properties of the hydraulic fluid inside a torque converter are the main topics of interest in this research. The primary goal is to investigate the applicability of various viscous fluids inside the torque converter. The Taguchi optimization method is adopted to analyse the fluid flow in a torque converter from a design perspective. Calculations are conducted in maximizing the pressure since greater the pressure, greater the torque developed. Using the values of the S/N ratios obtained, graphs are plotted. Computational Fluid Dynamics (CFD) analysis is also conducted.

Keywords: Hydraulic fluid, Taguchi's method, optimization, pressure, torque.

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Authors: Zeinab Hooshyar, Alireza Mehdizadeh

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Endovascular aneurysm repair is a new and minimally invasive repair for patients with abdominal aortic aneurysm (AAA). This method has potential advantages that are incomparable with other repair methods. However, the enlargement of aneurysm in the absence of endoleak, which is known as endotension, may occur as one of post-operative compliances of this method. Typically, endotension is mainly as a result of pressure transmitted to aneurysm sac by endovascular installed graft. After installation of graft the aneurysm sac reduces significantly but remains non-zero. There are some factors which affect this pressure transmitted. In this study, the geometry features of installed vascular graft have been considered. It is inferred that graft neck angle and iliac bifurcation angle are two factors which can affect the drag force on graft and consequently the pressure transmitted to aneurysm.

Keywords: Endovascular graft, transmitted pressure, Drag force, Finite Element Modeling, neck angle, iliac bifurcation angle.

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Authors: G. Zahedi, H. Yaghoobi

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Modeling of a heterogeneous industrial fixed bed reactor for selective dehydrogenation of heavy paraffin with Pt-Sn- Al2O3 catalyst has been the subject of current study. By applying mass balance, momentum balance for appropriate element of reactor and using pressure drop, rate and deactivation equations, a detailed model of the reactor has been obtained. Mass balance equations have been written for five different components. In order to estimate reactor production by the passage of time, the reactor model which is a set of partial differential equations, ordinary differential equations and algebraic equations has been solved numerically. Paraffins, olefins, dienes, aromatics and hydrogen mole percent as a function of time and reactor radius have been found by numerical solution of the model. Results of model have been compared with industrial reactor data at different operation times. The comparison successfully confirms validity of proposed model.

Keywords: Dehydrogenation, fixed bed reactor, modeling, linear alkyl benzene.

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Authors: Vivek V, Hafeez Syed, Darren W Terrell, Harit Naik, Halliburton

Abstract:

Applying a rigorous process to optimize the elements of a supply-chain network resulted in reduction of the waiting time for a service provider and customer. Different sources of downtime of hydraulic pressure controller/calibrator (HPC) were causing interruptions in the operations. The process examined all the issues to drive greater efficiencies. The issues included inherent design issues with HPC pump, contamination of the HPC with impurities, and the lead time required for annual calibration in the USA. HPC is used for mandatory testing/verification of formation tester/pressure measurement/logging-while drilling tools by oilfield service providers, including Halliburton. After market study andanalysis, it was concluded that the current HPC model is best suited in the oilfield industry. To use theexisting HPC model effectively, design andcontamination issues were addressed through design and process improvements. An optimum network is proposed after comparing different supply-chain models for calibration lead-time reduction.

Keywords: Hydraulic Pressure Controller/Calibrator, M/LWD, Pressure, FTWD

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Authors: H. Dehghan, E. Mahdavi, M. M. Heyhat

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In pressure vessels contain hydrogen, the role of hydrogen will be important because of hydrogen cracking problem. It is difficult to predict what is happened in metallurgical field spite of a lot of studies have been searched. The main role in controlling the mass diffusion as driving force is related to stress. In this study, finite element analysis is implemented to estimate material-s behavior associated with hydrogen embrittlement. For this purpose, one model of a pressure vessel is introduced that it has definite boundary and initial conditions. In fact, finite element is employed to solve the sequentially coupled mass diffusion with stress near a crack front in a pressure vessel. Modeling simulation intergrarnular fracture of AISI 4135 steel due to hydrogen is investigated. So, distribution of hydrogen and stress are obtained and they indicate that their maximum amounts occur near the crack front. This phenomenon is happened exactly the region between elastic and plastic field. Therefore, hydrogen is highly mobile and can diffuse through crystal lattice so that this zone is potential to trap high volume of hydrogen. Consequently, crack growth and fast fracture will be happened.

Keywords: Stress Intensity Factor, Mass Diffusion, FEM, Pressure Vessel

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Authors: M. Boumaza, Y. Bakhabkhi

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Water recycling represents an important challenge for many countries, in particular in countries where this natural resource is rare. On the other hand, in many operations, water is used as a cooling medium, as a high proportion of water consumed in industry is used for cooling purposes. Generally this water is rejected directly to the nature. This reject will cause serious environment damages as well as an important waste of this precious element.. On way to solve these problems is to reuse and recycle this warm water, through the use of natural cooling medium, such as air in a heat exchanger unit, known as a cooling tower. A poor performance, design or reliability of cooling towers will result in lower flow rate of cooling water an increase in the evaporation of water, an hence losses of water and energy. This paper which presents an experimental investigate of thermal and hydraulic performances of a mechanical cooling tower, enables to show that the water evaporation rate, Mev, increases with an increase in the air and water flow rates, as well as inlet water temperature and for fixed air flow rates, the pressure drop (ΔPw/Z) increases with increasing , L, due to the hydrodynamic behavior of the air/water flow.

Keywords: water, recycle, performance, cooling tower

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Authors: R. Afroundeh, T. Arimitsu, R. Yamanaka, C. S. Lian, T. Yunoki, T. Yano, K. Shirakawa

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We investigated this hypothesis that arterial CO2 pressure (PaCO2) drives ventilation (V.E) with a time delay duringrecovery from short impulse-like exercise (10 s) with work load of 200 watts. V.E and end tidal CO2 pressure (PETCO2) were measured continuously during rest, warming up, exercise and recovery periods. PaCO2 was predicted (PaCO2 pre) from PETCO2 and tidal volume (VT). PETCO2 and PaCO2 pre peaked at 20 s of recovery. V.E increased and peaked at the end of exercise and then decreased during recovery; however, it peaked again at 30 s of recovery, which was 10 s later than the peak of PaCO2 pre. The relationship between V. E and PaCO2pre was not significant by using data of them obtained at the same time but was significant by using data of V.E obtained 10 s later for data of PaCO2 pre. The results support our hypothesis that PaCO2 drives V.E with a time delay.

Keywords: Arterial CO2 pressure, impulse-like exercise, time delay, ventilation.

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Authors: S. Ben Saad, F. Ayad, H. Damotte

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This study deals with Computational Fluid Dynamics (CFD) studies of the interactions between the air flow and louvered fins which equipped the automotive heat exchangers. 3D numerical simulation results are obtained by using the ANSYS Fluent 13.0 code and compared to experimental data. The paper studies the effect of louver angle and louver pitch geometrical parameters, on overall thermal hydraulic performances of louvered fins. The comparison between CFD simulations and experimental data show that established 3-D CFD model gives a good agreement. The validation agrees, with about 7% of deviation respectively of friction and Colburn factors to experimental results. As first, it is found that the louver angle has a strong influence on the heat transfer rate. Then, louver angle and louver pitch variation of the louvers and their effects on thermal hydraulic performances are studied. In addition to this study, it is shown that the second half of the fin takes has a significant contribution on pressure drop increase without any increase in heat transfer.

Keywords: CFD simulations, automotive heat exchanger, performances.

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Authors: Sankar Chandrasekar, Rana Niranchan V.S., Joseph Sidharth Leon

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As the demand and prices of various petroleum products have been on the rise in recent years, there is a growing need for alternative fuels. Biodiesel, which consists of alkyl monoesters of fatty acids from vegetable oils and animal fats, is considered as an alternative to petroleum diesel. Biodiesel has comparable performance with that of diesel and has lower brake specific fuel consumption than diesel with significant reduction in emissions of CO, hydrocarbons (HC) and smoke with however, a slight increase in NOx emissions. This paper analyzes the effect of cooled exhaust gas recirculation in the combustion characteristics of a direct injection compression ignition engine using biodiesel blended fuel as opposed to the conventional system. The combustion parameters such as cylinder pressure, heat release rate, delay period and peak pressure were analyzed at various loads. The maximum cylinder pressure reduces as the fraction of biodiesel increases in the blend the maximum rate of pressure rise was found to be higher for diesel at higher engine loads.

Keywords: Cylinder pressure, delay period, EGR, heat release.

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Authors: Ali Raad Hassan

Abstract:

In this paper, an (irregular) case relating to base circle, root circle, and pressure angle has been discussed and a computer programme has been developed to simulate and plot spur gear tooth profile, including involute and trochoid curves based on the formulation of rack cutter using different values of pressure angle and profile shift factor and it gave the values of all important geometric parameters. The results showed the flexibility of this approach and versatility of the programme to draw many different cases of spur gear teeth of any module, pressure angle, profile shift factor, number of teeth and rack cutter tip radius. The procedure developed can be extended to produce finite element models of heretofore intractable geometrical forms, to exploring fabrication of nonstandard tooth forms also. Finite elements model of these irregular cases have been built using above programme, and modal analysis has been done using ANSYS software, and natural frequencies of these selected cases have been obtained and discussed.

Keywords: involute, trochoid, pressure angle, profile shift factor, natural frequency

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Authors: Hamed K. Arzani, Hamid K. Arzani, S.N. Kazi, A. Badarudin

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Numerical investigation into convective heat transfer of CuO-Water based nanofluid in a pipe with return bend under laminar flow conditions has been done. The impacts of Reynolds number and the volume concentration of nanoparticles on the flow and the convective heat transfer behaviour are investigated. The results indicate that the increase in Reynolds number leads to the enhancement of average Nusselt number, and the increase in specific heat in the presence of the nanofluid results in improvement in heat transfer. Also, the presence of the secondary flow in the curve plays a key role in increasing the average Nusselt number and it appears higher than the inlet and outlet tubes. However, the pressure drop curve increases significantly in the tubes with the increase in nanoparticles concentration.

Keywords: Laminar forced convection, nanofluid, curve, return bend, CFD.

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Authors: S. Gao, S. Srirattayawong

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In this study, a computational fluid dynamics (CFD) model has been developed for studying the effect of surface roughness profile on the EHL problem. The cylinders contact geometry, meshing and calculation of the conservation of mass and momentum equations are carried out using the commercial software packages ICEMCFD and ANSYS Fluent. The user defined functions (UDFs) for density, viscosity and elastic deformation of the cylinders as the functions of pressure and temperature are defined for the CFD model. Three different surface roughness profiles are created and incorporated into the CFD model. It is found that the developed CFD model can predict the characteristics of fluid flow and heat transfer in the EHL problem, including the main parameters such as pressure distribution, minimal film thickness, viscosity, and density changes. The results obtained show that the pressure profile at the center of the contact area directly relates to the roughness amplitude. A rough surface with kurtosis value of more than 3 has greater influence over the fluctuated shape of pressure distribution than in other cases.

Keywords: CFD, EHL, Kurtosis, Surface roughness.

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Authors: Elsa Eka Putri, N.S.V Kameswara Rao, M. A. Mannan

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The objective of this study is to evaluate the threshold stress of the clay with sand subgrade soil. Threshold stress can be defined as the stress level above which cyclic loading leads to excessive deformation and eventual failure. The thickness determination of highways formations using the threshold stress approach is a more realistic assessment of the soil behaviour because it is subjected to repeated loadings from moving vehicles. Threshold stress can be evaluated by plastic strain criterion, which is based on the accumulated plastic strain behaviour during cyclic loadings [1]. Several conditions of the all-round pressure the subgrade soil namely, zero confinement, low all-round pressure and high all-round pressure are investigated. The threshold stresses of various soil conditions are determined. Threshold stress of the soil are 60%, 31% and 38.6% for unconfined partially saturated sample, low effective stress saturated sample, high effective stress saturated sample respectively.

Keywords: threshold stress, cyclic loading, pore water pressure.

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Authors: Huei Chu Weng

Abstract:

This paper presents a study on the effect of second-order slip on forced convection through a long isoflux heated or cooled planar microchannel. The fully developed solutions of flow and thermal fields are analytically obtained on the basis of the second-order Maxwell-Burnett slip and local heat flux boundary conditions. Results reveal that when the average flow velocity increases or the wall heat flux amount decreases, the role of thermal creep becomes more insignificant, while the effect of second-order slip becomes larger. The second-order term in the Deissler slip boundary condition is found to contribute a positive velocity slip and then to lead to a lower pressure drop as well as a lower temperature rise for the heated-wall case or to a higher temperature rise for the cooled-wall case. These findings are contrary to predictions made by the Karniadakis slip model.

Keywords: Microfluidics, forced convection, thermal creep, second-order boundary conditions.

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Authors: Yuan Jie Kelvin Lu, Amin Chegenizadeh

Abstract:

Asphalt pavement itself is a mixture made up of mainly aggregates, binders, and fillers that acts as a composition used for pavement construction. An experimental program was setup to determine the fatigue performance test of Asphalt with three different grades of conventional binders. Asphalt specimen has achieved the maximum optimum bulk density and air voids with a consistent bulk density of 2.3 t/m3, with an air void of 5% ± 0.5, before loading into the Asphalt Mixture Performance Tested (AMPT) for fatigue test. The number of cycles is defined as the point where phase angle drops, which is caused by the formation of cracks due to the increasing micro cracks when asphalt is undergoing repeated cycles of loading. Thus, the data collected are analyzed using the drop of phase angle as failure criteria. Based in the data analyzed, it is evident that the fatigue life of asphalt lies on the grade of binder. The result obtained shows that all specimens do experience a drop in phase angle due to macro cracks in the asphalt specimen.

Keywords: Asphalt binder, AMPT, CX test, simplified–viscoelastic continuum damage (S-VECD).

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Authors: Abhishek Kumar Chandra, Kaushal Kishor, Wasim Khan, Dhananjay Singh, M. S. Alam

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Single phase fluid flow through series of uniform microchannels connected via transition section (converging-diverging section with or without throat) was analytically and numerically studied to characterize the flow within the channel and in the transition sections. Three sets of microchannels of diameters 100, 184, and 249 μm were considered for investigation. Each set contains 10 numbers of microchannels of length 20 mm, connected to each other in series via transition sections. Transition section consists of either converging-diverging section with throat or without throat. The effect of non-uniformity in microchannels on pressure drop was determined by passing water/air through the set of channels for Reynolds number 50 to 1000. Compressibility and rarefaction effects in transition sections were also tested analytically and numerically for air flow. The analytical and numerical results show that these configurations can be used in enhancement of transport processes. However, converging-diverging section without throat shows superior performance over with throat configuration.

Keywords: Contraction-expansion flow, integrated microchannel, microchannel network, single phase flow.

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Authors: Divya D. Nalayanda, William B. Fulton, Tza-Huei Wang, Fizan Abdullah

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In an effort to understand the preliminary effects of aerodynamic stress on alveolar epithelial cells, we developed a multifluidic cell culture platform capable of supporting alveolar cultures at an air-liquid interface under constant air flow and exposure to varying pressure stimuli on the apical side while providing nourishment on the basolateral plane. Our current study involved utilizing the platform to study the effect of basement membrane coating and addition of dexamethasone on cellular response to pressure in A549 and H441 alveolar epithelial cells.

Keywords: Aerodynamic stress, Air-liquid interface, Alveolar, Dexamethasone.

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Authors: Z. Hormozi Moghaddam, M. Mokhtari-Dizaji, M. Movahedin, M. E. Ravari

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Mechanical index (MI) is used for quantifying acoustic cavitation and the relationship between acoustic pressure and the frequency. In this study, modeling of the MI was applied to provide treatment protocol and to understand the effective physical processes on reproducibility of stem cells. The acoustic pressure and MI equations are modeled and solved to estimate optimal MI for 28, 40, 150 kHz and 1 MHz frequencies. Radial and axial acoustic pressure distribution was extracted. To validate the results of the modeling, the acoustic pressure in the water and near field depth was measured by a piston hydrophone. Results of modeling and experiments show that the model is consistent well to experimental results with 0.91 and 0.90 correlation of coefficient (p<0.05) for 1 MHz and 40 kHz. Low intensity ultrasound with 0.40 MI is more effective on the proliferation rate of the spermatogonial stem cells during the seven days of culture, in contrast, high MI has a harmful effect on the spermatogonial stem cells. This model provides proper treatment planning in vitro and in vivo by estimating the cavitation phenomenon.

Keywords: Ultrasound, mechanical index, modeling, stem cell.

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