Search results for: Cytotoxicity effect
4577 Ecotoxicity Evaluation and Suggestion of Remediation Method of ZnO Nanoparticles in Aqueous Phase
Authors: Hyunsang Kim, Younghun Kim, Younghee Kim, Sangku Lee
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We investigated ecotoxicity and performed experiment for removing ZnO nanoparticles in water. Short term exposure of hatching test using fertilized eggs (O. latipes) showed deformity in 5ppm of ZnO nanoparticles solution. And in 10ppm ZnO nanoparticles solution delayed hatching was observed. Hereine, chemical precipitation method was suggested for removing ZnO nanoparticles in water. The precipitated ZnO nanoparticles showed the form of ZnS after addition of Na2S, and the form of Zn3(PO4)2 for Na2HPO4. The removal efficiency of ZnO nanoparticles in water was closed to 100% for two cases. In ecotoxicity evaluation of as-precipitated ZnS and Zn3(PO4)2, they did not cause any acute toxicity for D. magna. It is noted that this precipitation treatment of ZnO is effective to reduce the potential cytotoxicity.Keywords: ZnO nanoparticles, ZnS, Zn3(PO4)2, ecotoxicity evaluation, chemical precipitation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 18694576 Ambipolar Effect Free Double Gate PN Diode Based Tunnel FET
Authors: Hardik Vaghela, Mamta Khosla, Balwindar Raj
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In this paper, we present and investigate a double gate PN diode based tunnel field effect transistor (DGPNTFET). The importance of proposed structure is that the formation of different drain doping is not required and ambipolar effect in OFF state is completely removed for this structure. Validation of this structure to behave like a Tunnel Field Effect Transistor (TFET) is carried out through energy band diagrams and transfer characteristics. Simulated result shows point subthreshold slope (SS) of 19.14 mV/decade and ON to OFF current ratio (ION / IOFF) of 2.66 × 1014 (ION at VGS=1.5V, VDS=1V and IOFF at VGS=0V, VDS=1V) for gate length of 20nm and HfO2 as gate oxide at room temperature. Which indicate that the DGPNTFET is a promising candidate for nano-scale, ambipolar free switch.
Keywords: Ambipolar effect, double gate PN diode based tunnel field effect transistor, high-κ dielectric material, subthreshold slope, tunnel field effect transistor.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 10044575 Effective Design Parameters on the End Effect in Single-Sided Linear Induction Motors
Authors: A. Zare Bazghaleh, M. R. Naghashan, H. Mahmoudimanesh, M. R. Meshkatoddini
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Linear induction motors are used in various industries but they have some specific phenomena which are the causes for some problems. The most important phenomenon is called end effect. End effect decreases efficiency, power factor and output force and unbalances the phase currents. This phenomenon is more important in medium and high speeds machines. In this paper a factor, EEF , is obtained by an accurate equivalent circuit model, to determine the end effect intensity. In this way, all of effective design parameters on end effect is described. Accuracy of this equivalent circuit model is evaluated by two dimensional finite-element analysis using ANSYS. The results show the accuracy of the equivalent circuit model.Keywords: Linear induction motor, end effect, equivalent circuitmodel, finite-element method.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 27924574 Conjugate Heat and Mass Transfer for MHD Mixed Convection with Viscous Dissipation and Radiation Effect for Viscoelastic Fluid past a Stretching Sheet
Authors: Kai-Long Hsiao, BorMing Lee
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In this study, an analysis has been performed for conjugate heat and mass transfer of a steady laminar boundary-layer mixed convection of magnetic hydrodynamic (MHD) flow with radiation effect of second grade subject to suction past a stretching sheet. Parameters E Nr, Gr, Gc, Ec and Sc represent the dominance of the viscoelastic fluid heat and mass transfer effect which have presented in governing equations, respectively. The similar transformation and the finite-difference method have been used to analyze the present problem. The conjugate heat and mass transfer results show that the non-Newtonian viscoelastic fluid has a better heat transfer effect than the Newtonian fluid. The free convection with a larger r G or c G has a good heat transfer effect better than a smaller r G or c G , and the radiative convection has a good heat transfer effect better than non-radiative convection.Keywords: Conjugate heat and mass transfer, Radiation effect, Magnetic effect, Viscoelastic fluid, Viscous dissipation, Stretchingsheet.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16794573 Battery Operation Time Enhancement Based On Alternating Battery Cell Discharge
Authors: Jong-Bae Lee, Seongsoo Lee
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This paper proposes an alternating discharge method of multiple battery cells to extend battery operation time. In the proposed method, two battery cells are periodically connected in turn to a mobile device and only one cell supply power while the other rests. Battery operation time of the connecting cell decreases due to rate-capacity effect, while that of the resting cell increases due to recovery effect. These two effects conflict each other, but recovery effect is generally larger than rate-capacity effect and battery lifetime is extended. It was found from the result that battery operation time increase about 7% by using alternating battery cell discharge.
Keywords: Battery, Recovery Effect, Rate-Capacity Effect, Low-Power, Alternating Battery Cell Discharge.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16864572 Skin Effect: A Natural Phenomenon for Minimization of Ground Bounce in VLSI RC Interconnect
Authors: Shilpi Lavania
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As the frequency of operation has attained a range of GHz and signal rise time continues to increase interconnect technology is suffering due to various high frequency effects as well as ground bounce problem. In some recent studies a high frequency effect i.e. skin effect has been modeled and its drawbacks have been discussed. This paper strives to make an impression on the advantage side of modeling skin effect for interconnect line. The proposed method has considered a CMOS with RC interconnect. Delay and noise considering ground bounce problem and with skin effect are discussed. The simulation results reveal an advantage of considering skin effect for minimization of ground bounce problem during the working of the model. Noise and delay variations with temperature are also presented.
Keywords: Interconnect, Skin effect, Ground Bounce, Delay, Noise.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 31384571 The Study of Chain Initiation Effect on the Direct Initiation of Detonation
Authors: Masoud Afrand, Saeid Farahat, Mehdi Alamkar
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In this research, effect of combustion reaction mechanism on direct initiation of detonation has been studied numerically. For this purpose, reaction mechanism has been simulated by using a three-step chemical kinetics model. The reaction scheme consists sequentially of a chain-initiation and chainbranching step, followed by a temperature -independent chaintermination. In a previous research, the effect of chain-branching on the direct initiation of detonation is studied. In this research effect of chain-initiation on direct initiation of detonation is investigated. For the investigation, first a characteristic time (τ) for each step of mechanism, which includes effect of different kinetics parameters, is defined. Then the effect of characteristic time of chain-initiation (τI) on critical initiation energy is studied. It is seen that increasing τI, causes critical initiation energy to be increased. Drawing detonation's shock pressure diagrams for different cases, shows that in small value of τI , kinetics has more important effect on the behavior of the wave.Keywords: Detonation initiation, Initiation energy, Reaction rate, Characteristic time.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19644570 Effects of Irradiation to Morphological, Physicochemical and Biocompatibility Properties of Carrageenan
Authors: Jhalique Jane R. Fojas, Rizalinda L. De Leon, Lucille V. Abad
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The characterization of κ-carrageenan could provide a better understanding of its functions in biological, medical and industrial applications. Chemical and physical analyses of carrageenan from seaweeds, Euchema cottonii L., were done to offer information on its properties and the effects of Co-60 γ-irradiation on its thermochemical characteristics. The structural and morphological characteristics of κ-carrageenan were determined using scanning electron microscopy (SEM) while the composition, molecular weight and thermal properties were determined using attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR), gel permeation chromatography (GPC), thermal gravimetric analysis (TGA) and differential scanning calorimetry (DSC). Further chemical analysis was done using hydrogen-1 nuclear magnetic resonance (1H NMR) and functional characteristics in terms of biocompatibility were evaluated using cytotoxicity test.Keywords: Biocompatibility, carrageenan, DSC, FTIR, GPC, irradiation, NMR, physicochemical, SEM, TGA.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 25574569 Mixed Convection with Radiation Effect over a Nonlinearly Stretching Sheet
Authors: Kai-Long Hsiao
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In this study, an analysis has been performed for free convection with radiation effect over a thermal forming nonlinearly stretching sheet. Parameters n, k0, Pr, G represent the dominance of the nonlinearly effect, radiation effect, heat transfer and free convection effects which have been presented in governing equations, respectively. The similarity transformation and the finite-difference methods have been used to analyze the present problem. From the results, we find that the effects of parameters n, k0, Pr, Ec and G to the nonlinearly stretching sheet. The increase of Prandtl number Pr, free convection parameter G or radiation parameter k0 resulting in the increase of heat transfer effects, but increase of the viscous dissipation number Ec will decrease of heat transfer effect.Keywords: Nonlinearly stretching sheet, Free convection, Finite-difference, Radiation effect.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 17564568 Investigation of Monochromatization Light Effect at Molecular/Atomic Level in Electronegative-Electropositive Gas Mixtures Plasma
Authors: L.C. Ciobotaru
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In electronegative-electropositive gas mixtures plasma, at a total pressure varying in the range of ten to hundred Torr, the appearance of a quasi-mochromatization effect of the emitted radiation was reported. This radiation could be the result of the generating mechanisms at molecular level, which is the case of the excimer radiation but also at atomic level. Thus, in the last case, in (Ne+1%Ar/Xe+H2) gas mixtures plasma in a dielectric barrier discharge, this effect, called M-effect, consists in the reduction of the discharge emission spectrum practice at one single, strong spectral line with λ = 585.3 nm. The present paper is concerned with the characteristics comparative investigation of the principal reaction mechanisms involved in the quasi-monochromatization effect existence in the case of the excimer radiation, respectively of the Meffect. Also, the paper points out the role of the metastable electronegative atoms in the appearance of the monochromatization – effect at atomic level.
Keywords: Colombian forces, Direct Harpoon reaction, Monochromatization – effect, Resonant polar three-body reaction.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 14074567 Analysis of the Long-term Effect of Office Lighting Environment on Human Reponses
Authors: D.Y. Su, C.C. Liu, C.M. Chiang, W. Wang
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This study aims to discuss the effect of illumination and the color temperature of the lighting source under the office lighting environment on human psychological and physiological responses. In this study, 21 healthy participants were selected, and the Ryodoraku measurement system was utilized to measure their skin resistance change.The findings indicated that the effect of the color temperature of the lighting source on human physiological responses is significant within 90 min after turning the lights on; while after 90 min the effect of illumination on human physiological responses is higher than that of the color temperature. Moreover, the cardiovascular, digestive and endocrine systems are prone to be affected by the indoor lighting environment. During the long-term exposure to high intensity of illumination and high color temperature (2000Lux -6500K), the effect on the psychological responses turned moderate after the human visual system adopted to the lighting environment. However, the effect of the Ryodoraku value on human physiological responses was more significant with the increase of perceptive time. The effect of long time exposure to a lighting environment on the physiological responses is greater than its effect on the psychological responses. This conclusion is different from the traditional public viewpoint that the effect on the psychological responses is greater.
Keywords: Autonomic nervous system, Human responses, Office Lighting Environment, Ryodoraku, Meridian
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19514566 Effect of Different Types of Highly Consumed Beverages on the Surface Structure of Orthodontic Restorative Material
Authors: A. Alhazza, B. Alnaser
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Orthodontic restorative materials are widely used for the direct restoration of teeth or for cosmetic dentistry purposes. These materials have helped to solve many dental problems, providing healthy and beautiful smiles for many patients. In this study, we aimed to investigate whether the pH value has an effect on the surface structure of a nanohybrid composite material. Five different types of highly consumed beverages were selected to examine their effect on the surface structure of the nanohybrid composite material. The beverages had different pH values in the range of 3–6, i.e., they were all acidic. The material was investigated under the hardest conditions of surface exposure to the drinks by immersing the material for a long period. The specimens were examined using scanning electron microscopy (SEM) at different magnifications to investigate the effect of these beverages on the morphology of the nanohybrid composite material discs. All specimens showed an effect including pores, cracks, protrusions, and surface roughness as a result of the beverages. The degree of effect differed from one experimental group to another, but there was no relationship between the pH (acidity) value and the degree of effect on the surface structure of the specimens.
Keywords: Acidity, beverage, SEM, dentistry.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 5384565 A Novel 14 nm Extended Body FinFET for Reduced Corner Effect, Self-Heating Effect, and Increased Drain Current
Authors: Cheng-Hsien Chang, Jyi-Tsong Lin, Po-Hsieh Lin, Hung-Pei Hsu, Chan-Hsiang Chang, Ming-Tsung Shih, Shih-Chuan Tseng, Min-Yan Lin
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In this paper, we have proposed a novel FinFET with extended body under the poly gate, which is called EB-FinFET, and its characteristic is demonstrated by using three-dimensional (3-D) numerical simulation. We have analyzed and compared it with conventional FinFET. The extended body height dependence on the drain induced barrier lowering (DIBL) and subthreshold swing (S.S) have been also investigated. According to the 3-D numerical simulation, the proposed structure has a firm structure, an acceptable short channel effect (SCE), a reduced series resistance, an increased on state drain current (I on) and a large normalized I DS. Furthermore, the structure can also improve corner effect and reduce self-heating effect due to the extended body. Our results show that the EBFinFET is excellent for nanoscale device.Keywords: SOI, FinFET, tri-gate, self-heating effect.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 28014564 The Effect of Ion Nitriding and Carbonitriding on Fretting Fatigue of Steels
Authors: V. Linhart, M.
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The paper deals with the effect of ion nitriding and carbonitriding on fatigue strength of steel parts under the fretting conditions. Instrumented fatigue tests were carried out on surface treated flat bars from EA1N and EA4T steels with different strength. The chosen surfacing decrease importantly an unfavorable fretting effect. Nitridation suppressed the unfavorable effect of fretting almost entirely, while the influence of carbonitridation was less striking. The results were compared with those ones obtained on bars without surfacing. The causes of favorable influence of surfacing are discussed.Keywords: Carbonitriding, fatigue, fretting, nitriding, steel.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 23764563 Study of the Sloshing Phenomenon in a Tank Filled Partially with Liquid Using CFD Simulation
Authors: Amit Kumar, Jaikumar V., Pradeep A. G., Shivakumar Bhavi
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Reducing sloshing is one of the major challenges in industries where transporting of liquid is involved. The present study investigates the sloshing effect for different liquid levels of 50% of the tank capacity. CFD simulation for two different baffle configurations has been carried out using a time-based multiphase Volume of fluid (VOF) scheme. Baffles were introduced to examine the sloshing effect inside the tank. Results were compared against the baseline case to assess the effectiveness of baffles; maximum liquid height over the period of the simulation was considered as the parameter for measuring the sloshing effect inside the tank. It was found that the addition of baffles reduced the sloshing effect inside the tank as compared to the baseline model.
Keywords: 3D effect of sloshing, multiphase volume of fluid, CFD, baffles
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 5304562 Scanning Electronic Microscopy for Analysis of the Effects of Surfactants on De-Wrinkling and Dispersion of Graphene
Authors: Kostandinos Katsamangas, B. Ramachandra Bhat, Fawad Inam
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Graphene was dispersed using a tip sonicator and the effect of surfactants were analysed. Sodium Dodecyl Sulphate (SDS) and Polyvinyl Alcohol (PVA) were compared to observe whether or not they had any effect on any de-wrinkling, and secondly whether they aided to achieve better dispersions. There is a huge demand for wrinkle free graphene as this will greatly increase its usefulness in various engineering applications. A comprehensive literature on dewrinkling graphene has been discussed. Low magnification Scanning Electronic Microscopy (SEM) was conducted to assess the quality of graphene de-wrinkling. The utilization of the PVA has significant effect on de-wrinkling whereas SDS had minimal effect on the dewrinkling of graphene.Keywords: De-wrinkling, dispersion, graphene, scanning electron microscopy.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19314561 ANP-based Intra and Inter-industry Analysis for Measuring Spillover Effect of ICT Industries
Authors: Yongyoon Suh, Yongtae Park
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The interaction among information and communication technology (ICT) industries is a recently ubiquitous phenomenon through fixed-mobile integration. To monitor the impact of interaction, previous research has mainly focused on measuring spillover effect among ICT industries using various methods. Among others, inter-industry analysis is one of the useful methods for examining spillover effect between industries. However, more complex ICT industries become, more important the impact within an industry is. Inter-industry analysis is limited in mirroring intra-relationships within an industry. Thus, this study applies the analytic network process (ANP) to measure the spillover effect, capturing all of the intra and inter-relationships. Using ANP-based intra and inter-industry analysis, the spillover effect is effectively measured, mirroring the complex structure of ICT industries. A main ICT industry and its linkages are also explored to show the current structure of ICT industries. The proposed approach is expected to allow policy makers to understand interactions of ICT industries and their impact.
Keywords: ANP, intra and inter-industry analysis, spillover effect
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 17374560 Interaction Effect of DGAT1 and Composite Genotype of Beta-Kappa Casein on Economic Milk Production Traits in Crossbred Holstein
Authors: A. Molee, N. Duanghaklang, P. Mernkrathoke
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The objective was to determine the single gene and interaction effect of composite genotype of beta-kappa casein and DGAT1 gene on milk yield (MY) and milk composition, content of milk fat (%FAT), milk protein (%PRO), solid not fat (%SNF), and total solid (%TS) in crossbred Holstein cows. Two hundred and thirty- one cows were genotyped with PCR-RFLP for DGAT1 and composite genotype data of beta-kappa casein from previous work were used. Two model, (1), and (2), was used to estimate single gene effect, and interaction effect on the traits, respectively. The significance of interaction effects on all traits were detected. Most traits have consistent pattern of significant when model (1), and (2) were compared, except the effect of composite genotype of betakappa casein on %FAT, and the effect of DGAT1 on MY, which the significant difference was detected in only model (1).The results suggested that when the optimum of all traits was necessary, interaction effect should be concerned.Keywords: composite genotype of beta-kappa casein, DGAT1gene, Milk composition, Milk yield
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16874559 Turkish Adolescents' Subjective Well-Being with Respect to Age, Gender and SES of Parents
Authors: Ali Eryılmaz
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In this research it is aimed that the effect of some demographic factors on Turkish Adolescents' subjective well being is investigated. 432 adolescents who are 247 girls and 185 boys are participated in this study. They are ages 15-17, and also are high school students. The Positive and Negative Affect Scale and Life Satisfaction Scale are used for measuring adolescents' subjective well being. The ANOVA method is used in order to examine the effect of ages. For gender differences, independent t-test method is used, and finally the Pearson Correlation method is used so as to examine the effect of socio economic statues of adolescents' parents. According to results, there is no gender difference on adolescents' subjective well being. On the other hand, SES and age are effect significantly lover level on adolescents' subjective well being.
Keywords: Subjective wellbeing, adolescents, and age, gender, SES.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 29414558 A Study of the Impact of Discrimination Experience on Life Satisfaction in Korean Women with Severe Disabilities
Authors: Soungwan Kim
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The present study analyzed the effect of discrimination experience on the life satisfaction in women with severe disabilities and the mediating effect of disability acceptance. In verifying this mediating effect of disability acceptance between discrimination experience and life satisfaction, both discrimination experience and disability acceptance were found to be statistically significant in the first and second phases. Disability acceptance was found to have a mediating effect on the relationship between discrimination experience and life satisfaction. Based on this finding, measures for enhancing the quality of life in individuals with disabilities that experience low levels of life satisfaction were proposed.Keywords: Disability Discrimination, Disability Acceptance, Life Satisfaction, Mediating Effect.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 17514557 A Super-Efficiency Model for Evaluating Efficiency in the Presence of Time Lag Effect
Authors: Yanshuang Zhang, Byungho Jeong
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In many cases, there are some time lag between the consumption of inputs and the production of outputs. This time lag effect should be considered in evaluating the performance of organizations. Recently, a couple of DEA models were developed for considering time lag effect in efficiency evaluation of research activities. Multi-periods input(MpI) and Multi-periods output(MpO) models are integrate models to calculate simple efficiency considering time lag effect. However, these models can’t discriminate efficient DMUs because of the nature of basic DEA model in which efficiency scores are limited to ‘1’. That is, efficient DMUs can’t be discriminated because their efficiency scores are same. Thus, this paper suggests a super-efficiency model for efficiency evaluation under the consideration of time lag effect based on the MpO model. A case example using a long term research project is given to compare the suggested model with the MpO model.
Keywords: DEA, Super-efficiency, Time Lag.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16194556 Anti-Inflammatory Activity of Topical Anthocyanins by Complexation and Niosomal Encapsulation
Authors: Aroonsri Priprem, Sucharat Limsitthichaikoon, Suttasinee Thappasarapong
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Anthocyanins are natural pigments with effective UV protection but their topical use could be limited due to their physicochemical characteristics. An attempt to overcome such limitations by complexation of 2 major anthocyanin-rich sources, C. ternatea and Z. mays, has potentiated its use as topical antiinflammatory. Cell studies indicate no cytotoxicity of the anthocyanin complex (AC) up to 1 mg/ml tested in HaCaT and human fore head fibroblasts by MTT. Croton oil-induced ear edema in Wistar rats suggests an effective dose of 5 mg/cm2 of AC as a topical anti-inflammatory in comparison to 0.5 mg/cm2 of fluocinolone acetonide. Niosomal encapsulation of the AC significantly prolonged the anti-inflammatory activity particularly at 8 h after topical application (p = 0.0001). The AC was not cytotoxic and its anti-inflammatory and activity was dose-dependent and prolonged by niosomal encapsulation. It has also shown to promote collagen type 1 production in cell culture. Thus, AC could be a potential candidate for topical anti-inflammatory agent from natural resources.
Keywords: Anthocyanin complex, ear edema, inflammation, niosomes, skin.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 31444555 In vitro Anti-tubercular Screening of Newly Synthesized Benzimidazole Derivatives
Authors: M. Shahar Yar, M. Mustaqeem Abdullah, Jaseela Majeed
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A series of 1-(1H-benzimidazol-2-yl)-3-(substituted phenyl)-2-propen-1-one were allowed to react with hydrazine hydrate and phenyl hydrazine in submitted reactions to get pyrazoline and phenyl pyrazoline derivatives. All the compounds entered for screening at the Tuberculosis Antimicrobial Acquisition and Coordinating Facility (TAACF) for their in vitro antibacterial activity against Mycobacterium tuberculosis H37Rv strain (ATCC 27294) using Microplate Alamar Blue Assay (MABA) susceptibility test. The results expressed as MIC (minimum inhibitory concentration) in μg/mL. Among the fifteen compounds, eight compounds were found to have MIC values less than 10 μg/mL. These were subjected for cytotoxicity assay in VERO cells to determine CC50 (cytotoxic concentration 50%) values and finally SI (Selectivity Index) were calculated. Compound (XV) 2-[5-(4- fluorophenyl)-1-phenyl-4,5-dihydro-1H-3-pyrazolyl]-1Hbenzimidazole was considered the best candidate of the series that could be a good starting point to develop new lead compounds in the fight against tuberculosis.
Keywords: anti-tubercular activity, benzimidazole, pyrazoline.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 18974554 Feature Extraction Technique for Prediction the Antigenic Variants of the Influenza Virus
Authors: Majid Forghani, Michael Khachay
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In genetics, the impact of neighboring amino acids on a target site is referred as the nearest-neighbor effect or simply neighbor effect. In this paper, a new method called wavelet particle decomposition representing the one-dimensional neighbor effect using wavelet packet decomposition is proposed. The main idea lies in known dependence of wavelet packet sub-bands on location and order of neighboring samples. The method decomposes the value of a signal sample into small values called particles that represent a part of the neighbor effect information. The results have shown that the information obtained from the particle decomposition can be used to create better model variables or features. As an example, the approach has been applied to improve the correlation of test and reference sequence distance with titer in the hemagglutination inhibition assay.Keywords: Antigenic variants, neighbor effect, wavelet packet, wavelet particle decomposition.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 7814553 The Effect of Job Motivation, Work Environment and Leadership on Organizational Citizenship Behavior, Job Satisfaction and Public Service Quality in Magetan, East Java,Indonesia
Authors: Budiyanto, Hening Widi Oetomo
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Magetan area is going to be the object of this research which is located in East Java, Indonesia. The data were obtained from 270 civil servants working at the Magetan District government. The data were analyzed using the Structural Equation Modeling with Partial Least Square program. The research showed the following findings: (1) job motivation variable has a positive and significant effect on organizational citizenship behavior (OCB); (2) work environment has positive and significant effect on OCB; (3) leadership variable has positive and significant effect on OCB; (4) job motivation variable has no significant effect on job satisfaction; (5) work environment variable has no significant effect on job satisfaction; (6) leadership variable has no significant effect on job satisfaction; (7) OCB is positively and significantly associated with job satisfaction; (8) job satisfaction variable is positively and significantly correlated with quality of public service at the Magetan District government.Keywords: Job Satisfaction, Leadership, OrganizationalCitizenship Behavior (OCB), Quality of Public Service
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 38954552 Research on Platform of Testing Reference Point Effect under Managerial Decision-making Simulation Environment
Authors: Yang Jiang, Zhuchao Yu, Zhu Wang, Xueying Hong
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Reference point effects of top managers exerts an influence on managerial decision-making behaviors. We introduces the main idea of developing the decision behavior testing system designed for top manager in team task circumstance. According to the theory of the reference point effect, study of testing experiments in the reference point effect is carried out. Under managerial decision-making simulation environment, a platform is designed for testing reference point effect. The system uses the outcome of the value of the reference point to report the characteristics of the decision behavior of top managers.
Keywords: reference point effect, decision-making behavior, top manager, managerial decision-making simulation environment.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 10684551 Radiation Heat Transfer Effect in Solid Oxide Fuel Cell: Application of the Lattice Boltzmann Method
Authors: Imen Mejri, Ahmed Mahmoudi, Mohamed A. Abbassi, Ahmed Omri
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The radiation effect within the solid anode, electrolyte, and cathode SOFC layers problem has been investigated in this paper. Energy equation is solved by the Lattice Boltzmann method (LBM). The Rosseland method is used to model the radiative transfer in the electrodes. The Schuster-Schwarzschild method is used to model the radiative transfer in the electrolyte. Without radiative effect, the found results are in good agreement with those published. The obtained results show that the radiative effect can be neglected.
Keywords: SOFC, lattice Boltzmann method, conduction, radiation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 24514550 Evaluation of South African Plants with Acaricide Activity against Ticks
Authors: G. Fouché, J. N. Eloff, K. Wellington
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Acaricides are commonly used to control ticks but are toxic, harmful to the environment and too expensive to resource-limited farmers. Traditionally, many communities in South Africa rely on a wide range of indigenous practices to keep their livestock healthy. One of these health care practices includes the use of medicinal plants and this offers an alternative to conventional medicine. An investigation was conducted at the CSIR in South Africa, and selected indigenous plants used in communities were scientifically evaluated for the management of ticks in animals. 17 plants were selected from 239 plants used traditionally in South Africa. Two different organic extracts were prepared from the 17 samples, resulting in 34 plant samples. These were tested for efficacy against two tick species, namely Rhipicephalus microplus and Rhipicephalus turanicus. The plant extracts were also screened against Vero cells and most were found to have low cytotoxicity. This study has shown that there is potential for the development of botanicals as natural acaricides against ticks that are non-toxic and environmentally benign.
Keywords: Rhipicephalus microplus, Rhipicephalus turanicus, ticks, plant extracts, South Africa.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 12224549 Evaluation of the End Effect Impact on the Torsion Test for Determining the Shear Modulus of a Timber Beam through a Photogrammetry Approach
Authors: Niaz Gharavi, Hexin Zhang, Yanjun Xie
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The timber beam end effect in the torsion test is evaluated using binocular stereo vision system. It is recommended by BS EN 408:2010+A1:2012 to exclude a distance of two to three times of cross-sectional thickness (b) from ends to avoid the end effect; whereas, this study indicates that this distance is not sufficiently far enough to remove this effect in slender cross-sections. The shear modulus of six timber beams with different aspect ratios is determined at the various angles and cross-sections. The result of this experiment shows that the end affected span of each specimen varies depending on their aspect ratios. It is concluded that by increasing the aspect ratio this span will increase. However, by increasing the distance from the ends to the values greater than 6b, the shear modulus trend becomes constant and end effect will be negligible. Moreover, it is concluded that end affected span is preferred to be depth-dependent rather than thickness-dependant.Keywords: End effect, structural-size torsion test, shear properties, timber engineering, binocular stereo vision.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 13634548 Approximate Confidence Interval for Effect Size Base on Bootstrap Resampling Method
Authors: S. Phanyaem
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This paper presents the confidence intervals for the effect size base on bootstrap resampling method. The meta-analytic confidence interval for effect size is proposed that are easy to compute. A Monte Carlo simulation study was conducted to compare the performance of the proposed confidence intervals with the existing confidence intervals. The best confidence interval method will have a coverage probability close to 0.95. Simulation results have shown that our proposed confidence intervals perform well in terms of coverage probability and expected length.Keywords: Effect size, confidence interval, Bootstrap Method.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1147