@article{(Open Science Index):https://publications.waset.org/pdf/10000421,
	  title     = {Anti-Inflammatory Activity of Topical Anthocyanins by Complexation and Niosomal Encapsulation},
	  author    = {Aroonsri Priprem and  Sucharat Limsitthichaikoon and  Suttasinee Thappasarapong},
	  country	= {},
	  institution	= {},
	  abstract     = {Anthocyanins are natural pigments with effective UV
protection but their topical use could be limited due to their
physicochemical characteristics. An attempt to overcome such
limitations by complexation of 2 major anthocyanin-rich sources, C.
ternatea and Z. mays, has potentiated its use as topical antiinflammatory.
Cell studies indicate no cytotoxicity of the
anthocyanin complex (AC) up to 1 mg/ml tested in HaCaT and
human fore head fibroblasts by MTT. Croton oil-induced ear edema
in Wistar rats suggests an effective dose of 5 mg/cm2 of AC as a
topical anti-inflammatory in comparison to 0.5 mg/cm2 of
fluocinolone acetonide. Niosomal encapsulation of the AC
significantly prolonged the anti-inflammatory activity particularly at
8 h after topical application (p = 0.0001). The AC was not cytotoxic
and its anti-inflammatory and activity was dose-dependent and
prolonged by niosomal encapsulation. It has also shown to promote
collagen type 1 production in cell culture. Thus, AC could be a
potential candidate for topical anti-inflammatory agent from natural
	    journal   = {International Journal of Chemical and Molecular Engineering},
	  volume    = {9},
	  number    = {2},
	  year      = {2015},
	  pages     = {142 - 146},
	  ee        = {https://publications.waset.org/pdf/10000421},
	  url   	= {https://publications.waset.org/vol/98},
	  bibsource = {https://publications.waset.org/},
	  issn  	= {eISSN: 1307-6892},
	  publisher = {World Academy of Science, Engineering and Technology},
	  index 	= {Open Science Index 98, 2015},