Search results for: %ERD of upper Alpha band.
Commenced in January 2007
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Edition: International
Paper Count: 989

Search results for: %ERD of upper Alpha band.

539 Design and Layout of Two Stage High Band Width Operational Amplifier

Authors: Yasir Mahmood Qureshi

Abstract:

This paper presents the design and layout of a two stage, high speed operational amplifiers using standard 0.35um CMOS technology. The design procedure involves designing the bias circuit, the differential input pair, and the gain stage using CAD tools. Both schematic and layout of the operational amplifier along with the comparison in the results of the two has been presented. The operational amplifier designed, has a gain of 93.51db at low frequencies. It has a gain bandwidth product of 55.07MHz, phase margin of 51.9º and a slew rate of 22v/us for a load of capacitor of 10pF.

Keywords: Gain bandwidth product, Operational Amplifier, phase margin, slew rate.

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538 Adaptive Nonparametric Approach for Guaranteed Real-Time Detection of Targeted Signals in Multichannel Monitoring Systems

Authors: Andrey V. Timofeev

Abstract:

An adaptive nonparametric method is proposed for stable real-time detection of seismoacoustic sources in multichannel C-OTDR systems with a significant number of channels. This method guarantees given upper boundaries for probabilities of Type I and Type II errors. Properties of the proposed method are rigorously proved. The results of practical applications of the proposed method in a real C-OTDR-system are presented in this report.

Keywords: Adaptive detection, change point, interval estimation, guaranteed detection, multichannel monitoring systems.

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537 Assessment of Sediment Quality According To Heavy Metal Status in the West Port of Malaysia

Authors: B.Tavakoly Sany, A.H .Sulaiman, GH. Monazami, A. Salleh

Abstract:

Eight heavy metals (Cu, Cr, Zn, Hg, Pb, Cd, Ni and As) were analyzed in sediment samples in the dry and wet seasons from November 2009 to October 2010 in West Port of Peninsular Malaysia. The heavy metal concentrations (mg/kg dry weight) were ranged from 23.4 to 98.3 for Zn, 22.3 to 80 for Pb, 7.4 to 27.6 Cu, 0.244 to 3.53 for Cd, 7.2 to 22.2 for Ni, 20.2 to 162 for As, 0.11 to 0.409 for Hg and 11.5 to 61.5 for Cr. Metals concentrations in dry season were higher than the rainy season except in cupper and chromium. Analysis of variance with Statistical Analysis System (SAS) shows that the mean concentration of metals in the two seasons (α level=0.05) are not significantly different which shows that the metals were held firmly in the matrix of sediment. Also there are significant differences between control point station with other stations. According to the Interim Sediment Quality guidelines (ISQG), the metal concentrations are moderately polluted, except in arsenic which shows the highest level of pollution.

Keywords: Heavy metals, sediment quality guidelines, west port.

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536 The Relation between Social Capital and Trust with Social Network Analysis

Authors: Safak Baykal

Abstract:

The purpose of this study is analyzing the relationship between trust and social capital of people with using Social Network Analysis. In this study, two aspects of social capital will be focused: Bonding, homophilous social capital (BoSC), and Bridging, heterophilous social capital (BrSC). These two aspects diverge each other regarding to the social theories. The other concept of the study is Trust (Tr), namely interpersonal trust, willing to ascribe good intentions to and have confidence in the words and actions of other people. In this study, the sample group, 61 people, was selected from a private firm from the defense industry. The relation between BoSC/BrSC and Tr is shown by using Social Network Analysis (SNA) and statistical analysis with Likert type-questionnaire. The results of the analysis show the Cronbach’s alpha value is 0.756 and social capital values (BoSC/BrSC) is not correlated with Tr values of the people.

Keywords: Social capital, interpersonal trust, social network analysis (SNA).

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535 Investigation of Split TCSC on Kanpur-Ballabhgarh Transmission System

Authors: S. Meikandasivam, D. Vijayakumar, Rajesh Kumar Nema, Shailendra Kumar Jain

Abstract:

This paper investigates the performance of the single TCSC and proposed split TCSC on transmission system where India’s first TCSC project is installed in Kanpur - Ballabhgarh (KB) line to ensure the fine tuning of line reactance by proposed split TCSC in place of existing KB TCSC. A three phase KB transmission system is developed in MATLAB/Simulink (SimPowerSystems) for

  1. without any compensation,
  2. with fixed capacitor (FC),
  3. with FC + existing KB TCSC and
  4. with FC + proposed split TCSC

The KB system is analyzed for a step variation of load and performance of the system is investigated with a closed loop reactance control method.

Keywords: Single TCSC, Split TCSC, TCSC Reactance characteristic curve, Power flow analysis, Sensitivity analysis.

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534 Analysis of Socio-Cultural Obstacles for Dissemination of Nanotechnology from Iran's Agricultural Experts Perspective

Authors: S. M. Mirdamadi, S. Esmaeili, S. A. Tohidloo

Abstract:

The main purpose of this research was to analyze Socio-Cultural obstacles of disseminating of nanotechnology in Iran's agricultural section. One hundred twenty eight out of a total of 190 researchers with different levels of expertise in and familiarity with nanotechnology were randomly selected and questionnaires completed by them. Face validity have been done by expert's suggestion and correction, reliability by using Cronbakh-Alpha formula. The results of a factor analysis showed variation for different factors. For cultural factors 19/475 percent, for management 13/139 percent, information factor 11/277 percent, production factor 9/703 percent, social factor 9/267 percent, and for attitude factor it became 8/947 percent. Also results indicated that socio-cultural factors were the most important obstacle for nanotechnology dissemination in agricultural section in Iran.

Keywords: Agriculture, Iran, nanotechnology, public perception, social-cultural obstacles.

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533 A Centroid Ranking Approach Based Fuzzy MCDM Model

Authors: T. C. Chu, S.H. Wu

Abstract:

This paper suggests ranking alternatives under fuzzy MCDM (multiple criteria decision making) via an centroid based ranking approach, where criteria are classified to benefit qualitative, benefit quantitative and cost quantitative ones. The ratings of alternatives versus qualitative criteria and the importance weights of all criteria are assessed in linguistic values represented by fuzzy numbers. The membership function for the final fuzzy evaluation value of each alternative can be developed through α-cuts and interval arithmetic of fuzzy numbers. The distance between the original point and the relative centroid is applied to defuzzify the final fuzzy evaluation values in order to rank alternatives. Finally a numerical example demonstrates the computation procedure of the proposed model.

Keywords: Fuzzy MCDM, Criteria, Fuzzy number, Ranking, Relative centroid.

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532 A Low Profile Dual Polarized Slot Coupled Patch Antenna

Authors: Mingde Du, Dong Han

Abstract:

A low profile, dual polarized, slot coupled patch antenna is designed and developed in this paper. The antenna has a measured bandwidth of 17.2% for return loss > 15 dB and pair ports isolation >23 dB. The gain of the antenna is over 10 dBi and the half power beam widths (HPBW) of the antenna are 80±3o in the horizontal plane and 39±2o in the vertical plane. The cross polarization discrimination (XPD) is less than 20 dB in HPBW. Within the operating band, the performances of good impedance match, high ports isolation, low cross polarization, and stable radiation patterns are achieved.

Keywords: Dual polarized, patch antenna, slot coupled, base station antenna.

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531 Implementation Issues of Industrial PID Controller and Their Remedies

Authors: C. B. Vishwakarma

Abstract:

We elaborated the parallel and series Proportional, Integral and Derivative (PID) controllers, which are being used in industries. Various issues, which are very often faced by control engineers while designing the PID controllers for industrial systems are described. The effect of measurement noise on the actuator due to derivative term of a PID controller has been explained in detail. Similarly, proportional kick, derivative kick, saturation tendency of the actuator and reverse phenomena of an industrial process have been summarized. Moreover, we meticulously explained the remedies of the all issues of the parallel industrial PID controller.

Keywords: Band-width limited derivative control, derivative kick, proportional kick, reverse acting controller, series PID controller.

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530 Utilization and Characterizations of Olive Oil Industry By-Products

Authors: Sawsan Dacrory, Hussein Abou-Yousef, Samir Kamel, Ragab E. Abou-Zeid, Mohamed S. Abdel-Aziz, Mohamed Elbadry

Abstract:

A considerable amount of lignocellulosic by-product could be obtained from olive pulp during olive oil extraction industry. The major constituents of the olive pulp are husks and seeds. The separation of each portion of olive pulp (seeds and husks) was carried out by water flotation where seeds were sediment in the bottom. Both seeds and husks were dignified by 15% NaOH followed by complete lignin removal by using sodium chlorite in acidic medium. The isolated holocellulose, α-cellulose, hydrogel and CMC of both seeds and husk fractions were characterized by FTIR and SEM. The present study focused on the investigation of the chemical components of the lignocellulosic fraction of olive pulp and using them in medical application. Carboxymethyl cellulose (CMC) is produced and applied in the preparation of antimicrobial hydrogel.

Keywords: Carboxymethyl cellulose, cellulose, hydrogel olive pulp.

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529 A Joint Routing-Scheduling Approach for Throughput Optimization in WMNs

Authors: Hossein Nourkhiz Mahjoub, Mohsen Shiva

Abstract:

Wireless Mesh Networking is a promising proposal for broadband data transmission in a large area with low cost and acceptable QoS. These features- trade offs in WMNs is a hot research field nowadays. In this paper a mathematical optimization framework has been developed to maximize throughput according to upper bound delay constraints. IEEE 802.11 based infrastructure backhauling mode of WMNs has been considered to formulate the MINLP optimization problem. Proposed method gives the full routing and scheduling procedure in WMN in order to obtain mentioned goals.

Keywords: Mixed-Integer Non Linear Programming (MINLP), routing and scheduling, throughput, wireless mesh networks (WMNs)

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528 Lamb Waves in Plates Subjected to Uniaxial Stresses

Authors: Munawwar Mohabuth, Andrei Kotousov, Ching-Tai Ng

Abstract:

On the basis of the theory of nonlinear elasticity, the effect of homogeneous stress on the propagation of Lamb waves in an initially isotropic hyperelastic plate is analysed. The equations governing the propagation of small amplitude waves in the prestressed plate are derived using the theory of small deformations superimposed on large deformations. By enforcing traction free boundary conditions at the upper and lower surfaces of the plate, acoustoelastic dispersion equations for Lamb wave propagation are obtained, which are solved numerically. Results are given for an aluminum plate subjected to a range of applied stresses.

Keywords: Acoustoelasticity, dispersion, finite deformation, lamb waves.

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527 PSRR Enhanced LDO Regulator Using Noise Sensing Circuit

Authors: Min-ju Kwon, Chae-won Kim, Jeong-yun Seo, Hee-guk Chae, Yong-seo Koo

Abstract:

In this paper, we presented the LDO (low-dropout) regulator which enhanced the PSRR by applying the constant current source generation technique through the BGR (Band Gap Reference) to form the noise sensing circuit. The current source through the BGR has a constant current value even if the applied voltage varies. Then, the noise sensing circuit, which is composed of the current source through the BGR, operated between the error amplifier and the pass transistor gate of the LDO regulator. As a result, the LDO regulator has a PSRR of -68.2 dB at 1k Hz, -45.85 dB at 1 MHz and -45 dB at 10 MHz. the other performance of the proposed LDO was maintained at the same level of the conventional LDO regulator.

Keywords: LDO regulator, noise sensing circuit, current reference, pass transistor.

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526 Performance of Total Vector Error of an Estimated Phasor within Local Area Networks

Authors: Ahmed Abdolkhalig, Rastko Zivanovic

Abstract:

This paper evaluates the Total Vector Error of an estimated Phasor as define in IEEE C37.118 standard within different medium access in Local Area Networks (LAN). Three different LAN models (CSMA/CD, CSMA/AMP and Switched Ethernet) are evaluated. The Total Vector Error of the estimated Phasor has been evaluated for the effect of Nodes Number under the standardized network Band-width values defined in IEC 61850-9-2 communication standard (i.e. 0.1, 1 and 10 Gbps).

Keywords: Phasor, Local Area Network, Total Vector Error, IEEE C37.118, IEC 61850.

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525 Single Port Overlay Cognitive Radio Using Reconfigurable Filtennas

Authors: V. Nagaraju, Tapas Bapu. B. R, Beryl J. Victor

Abstract:

In this paper cognitive radio is presented and the spectrum overlay cognitive radio antenna system is detailed. A UWB antenna with frequency reconfigurable characteristics is proposed. The reconfigurability is achieved when the filter is integrated to the feeding line of the single port overlay cognitive radio. When activated, the filter can transform the UWB frequency response into a reconfigurable narrowband one, which is suitable for the communication operation of the CR system. Here single port overlay cognitive radio antenna is designed and simulated using Ansoft High Frequency Structure Simulator (HFSS).

Keywords: Band-pass filter, Cognitive radio, filtenna, frequency reconfigurable, ultra-wideband antenna.

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524 A Mini Radar System for Low Altitude Targets Detection

Authors: Kangkang Wu, Kaizhi Wang, Zhijun Yuan

Abstract:

This paper deals with a mini radar system aimed at detecting small targets at the low latitude. The radar operates at Ku-band in the frequency modulated continuous wave (FMCW) mode with two receiving channels. The radar system has the characteristics of compactness, mobility, and low power consumption. This paper focuses on the implementation of the radar system, and the Block least mean square (Block LMS) algorithm is applied to minimize the fortuitous distortion. It is validated from a series of experiments that the track of the unmanned aerial vehicle (UAV) can be easily distinguished with the radar system.

Keywords: Unmanned aerial vehicle, interference, block least mean square, frequency modulated continuous wave.

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523 Dempster-Shafer's Approach for Autonomous Virtual Agent Navigation in Virtual Environments

Authors: Jafreezal Jaafar, Eric McKenzie

Abstract:

This paper presents a solution for the behavioural animation of autonomous virtual agent navigation in virtual environments. We focus on using Dempster-Shafer-s Theory of Evidence in developing visual sensor for virtual agent. The role of the visual sensor is to capture the information about the virtual environment or identifie which part of an obstacle can be seen from the position of the virtual agent. This information is require for vitual agent to coordinate navigation in virtual environment. The virual agent uses fuzzy controller as a navigation system and Fuzzy α - level for the action selection method. The result clearly demonstrates the path produced is reasonably smooth even though there is some sharp turn and also still not diverted too far from the potential shortest path. This had indicated the benefit of our method, where more reliable and accurate paths produced during navigation task.

Keywords: Agent, navigation, Dempster Shafer, fuzzy logic.

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522 Plasmonic Absorption Enhancement in Au/CdS Nanocomposite

Authors: K. Easawi, M. Nabil, T. Abdallah, S. Negm, H. Talaat

Abstract:

Composite nanostructures of metal core/semiconductor shell (Au/CdS) configuration were prepared using organometalic method. UV-Vis spectra for the Au/CdS colloids show initially two well separated bands, corresponding to surface plasmon of the Au core, and the exciton of CdS shell. The absorption of CdS shell is enhanced, while the Au plasmon band is suppressed as the shell thickness increases. The shell sizes were estimated from the optical spectra using the effective mass approximation model (EMA), and compared to the sizes of the Au core and CdS shell measured by high resolution transmission electron microscope (HRTEM). The changes in the absorption features are discussed in terms of gradual increase in the coupling strength of the Au core surface plasmon and the exciton in the CdS. leading to charge transfer and modification of electron oscillation in Au core.

Keywords: Nanocomposites, Plasmonics.

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521 Influence of Gas-Liquid Separator Design on Performance of Airlift Bioreactors

Authors: Mateus N. Esperança, Marcel O. Cerri, Alberto C. Badino

Abstract:

The performance of airlift bioreactors are closely related with their geometry, especially the gas-liquid separator design. In this study, the influence of the gas-liquid separator geometry on oxygen transfer and gas hold-up was evaluated in 10-L concentric-tube airlift bioreactor operating with distilled water and xanthan gum solution. The specific airflow rate (ɸAIR) exhibited the higher effect on the oxygen transfer coefficient (kLa) for both fluids. While the gas-liquid separator openness angle (α) and liquid volume fraction on the gas-liquid separator (VGLS) have presented opposite effects on oxygen mass transfer, they affected negatively the global gas hold-up of distilled water system. The best degassing zone geometry corresponded to a 90° openness angle with 10% of the liquid on it.

Keywords: Airlift bioreactor, gas holdup, gas-liquid separator, oxygen transfer.

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520 Metaheuristics Methods (GA and ACO) for Minimizing the Length of Freeman Chain Code from Handwritten Isolated Characters

Authors: Dewi Nasien, Habibollah Haron, Siti SophiayatiYuhaniz

Abstract:

This paper presents a comparison of metaheuristic algorithms, Genetic Algorithm (GA) and Ant Colony Optimization (ACO), in producing freeman chain code (FCC). The main problem in representing characters using FCC is the length of the FCC depends on the starting points. Isolated characters, especially the upper-case characters, usually have branches that make the traversing process difficult. The study in FCC construction using one continuous route has not been widely explored. This is our motivation to use the population-based metaheuristics. The experimental result shows that the route length using GA is better than ACO, however, ACO is better in computation time than GA.

Keywords: Handwriting Recognition, Feature Extraction, Freeman Chain Code, Genetic Algorithm and Ant ColonyOptimization.

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519 A Computationally Efficient Design for Prototype Filters of an M-Channel Cosine Modulated Filter Bank

Authors: Neela. R. Rayavarapu, Neelam Rup Prakash

Abstract:

The paper discusses a computationally efficient method for the design of prototype filters required for the implementation of an M-band cosine modulated filter bank. The prototype filter is formulated as an optimum interpolated FIR filter. The optimum interpolation factor requiring minimum number of multipliers is used. The model filter as well as the image suppressor will be designed using the Kaiser window. The method will seek to optimize a single parameter namely cutoff frequency to minimize the distortion in the overlapping passband.

Keywords: Cosine modulated filter bank, interpolated FIR filter, optimum interpolation factor, prototype filter.

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518 Amino Acid Based Biodegradable Amphiphilic Polymers and Micelles as Drug Delivery Systems: Synthesis and Study

Authors: Sophio Kobauri, Vladimir P. Torchilin, David Tugushi, Ramaz Katsarava

Abstract:

Nanotherapy is an actual newest mode of treatment numerous diseases using nanoparticles (NPs) loading with different pharmaceuticals. NPs of biodegradable polymeric micelles (PMs) are gaining increased attention for their numerous and attractive abilities to be used in a variety of applications in the various fields of medicine. The present paper deals with the synthesis of a class of biodegradable micelle-forming polymers, namely ABA triblock-copolymer in which A-blocks represent amino-poly(ethylene glycol) (H2N-PEG) and B-block is biodegradable amino acid-based poly(ester amide) constituted of α-amino acid – L-phenylalanine. The obtained copolymer formed micelles of 70±4 nm size at 10 mg/mL concentration.

Keywords: Amino acids, biodegradable poly(ester amide), amphiphilic triblock-copolymer, micelles.

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517 Structural, Optical and Ferroelectric Properties of BaTiO3 Sintered at Different Temperatures

Authors: Anurag Gaur, Neha Sharma

Abstract:

In this work, we have synthesized BaTiO3 via sol gel method by sintering at different temperatures (600, 700, 800, 900, 10000C) and studied their structural, optical and ferroelectric properties through X-ray diffraction (XRD), UV-Vis spectrophotometer and PE Loop Tracer. X-ray diffraction patterns of barium titanate samples show that the peaks of the diffractogram are successfully indexed with the tetragonal and cubic structure of BaTiO3. The Optical band gap calculated through UV Visible spectrophotometer varies from 4.37 to 3.80 eV for the samples sintered at 600 to 10000C, respectively. The particle size calculated through transmission electron microscopy varies from 20 to 40 nm for the samples sintered at 600 to 10000C, respectively. Moreover, it has been observed that the ferroelectricity increases as we increase the sintering temperature.

Keywords: Nanostructures, Ferroelectricity, Sol-gel method.

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516 Some New Inequalities for Eigenvalues of the Hadamard Product and the Fan Product of Matrices

Authors: Jing Li, Guang Zhou

Abstract:

Let A and B be nonnegative matrices. A new upper bound on the spectral radius ρ(A◦B) is obtained. Meanwhile, a new lower bound on the smallest eigenvalue q(AB) for the Fan product, and a new lower bound on the minimum eigenvalue q(B ◦A−1) for the Hadamard product of B and A−1 of two nonsingular M-matrices A and B are given. Some results of comparison are also given in theory. To illustrate our results, numerical examples are considered.

Keywords: Hadamard product, Fan product; nonnegative matrix, M-matrix, Spectral radius, Minimum eigenvalue, 1-path cover.

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515 Grooved Linear Microstrip Patch Antenna Array

Authors: Ayesha Aslam, F A Bhatti

Abstract:

A simple impedance matching technique for inset feed grooved microstrip patch antenna based on the concept of coplanar waveguide feed line has been developed and investigated for a printed antenna at X-Band frequency of 10GHz. The proposed technique has been used in the design of Linear Grooved Microstrip patch antenna array. The characteristics of the antenna are determined in terms of Return loss, VSWR, gain, radiation pattern etc. The measured and simulated results presented are found to be in good agreement.

Keywords: Gain, Microstrip patch, return loss, VSWR, Radiation pattern, CPW Feed, Inset feed.

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514 Theoretical Calculation of Electrical and Optical Properties of BaZrO3

Authors: Leyla Safaie Kouchaksaraie

Abstract:

In this project electrical and optical properties of BaZrO3 have been accomplished through the full-potential linear augmented plane wave (FP-LAPW) by applying Wein2k software. In this study band structure, density of state, gap energy, refractive index and optical conduction have been studied. The results of calculations show that BaZrO3 is an insulator with an indirect gap in which 3.2 ev and studied refractive index equal 2.07. These results are in accordance with the ones obtained in experimental researches.

Keywords: Density Functional Theory (DFT), Full PotentialLinearized Augmented Plane Wave (Fp-LAPW), GeneralizedGradient Approximation (GGA), Linearized Augmented Plane Wave(LAPW), Local Density Approximation (LDA)

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513 Time and Distance Dependence of Protons Energy Loss for Laser (pw-ps) Fusion Driven Ion Acceleration

Authors: B. Malekynia

Abstract:

The anomalous generation of plasma blocks by interaction of petawatt-picosecond laser pulses permits side-on ignition of uncompressed solid fusion fuel following an improved application of the hydrodynamic Chu-model for deuterium-tritium. The new possibility of side-on laser ignition depends on accelerated ions and produced ions beams of high energy particles by the nonlinear ponderomotive force of the laser pulse in the plasma block, a re-evaluation of the early hydrodynamic analysis for ignition of inertial fusion by including inhibition factor, collective effect of stopping power of alpha particles and the energy loss rate reabsorption to plasma by the protons of plasma blocks being reduced by about a factor 40.

Keywords: Block ignition, Charged particles, Reabsorption, Skin layer ponderomotive acceleration.

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512 Heat Transfer and Friction Factor Study for Triangular Duct Solar Air Heater Having Discrete V-Shaped Ribs

Authors: Varun

Abstract:

Solar energy is a good option among renewable energy resources due to its easy availability and abundance. The simplest and most efficient way to utilize solar energy is to convert it into thermal energy and this can be done with the help of solar collectors. The thermal performance of such collectors is poor due to less heat transfer from the collector surface to air. In this work, experimental investigations of single pass solar air heater having triangular duct and provided with roughness element on the underside of the absorber plate. V-shaped ribs are used for investigation having three different values of relative roughness pitch (p/e) ranges from 4- 16 for a fixed value of angle of attack (α), relative roughness height (e/Dh) and a relative gap distance (d/x) values are 60°, 0.044 and 0.60 respectively. Result shows that considerable augmentation in heat transfer has been obtained by providing roughness.

Keywords: Artificial roughness, Solar Air heater, Triangular duct, V-Shaped Ribs.

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511 Temperature-dependent Structural Perturbation of Tuna Myoglobin

Authors: Yoshihiro Ochiai

Abstract:

To unveil the mechanism of fast autooxidation of fish myoglobins, the effect of temperature on the structural change of tuna myoglobin was investigated. Purified myoglobin was subjected to preincubation at 5, 20, 50 and 40oC. Overall helical structural decay through thermal treatment up to 95oC was monitored by circular dichroism spectrometry, while the structural changes around the heme pocket was measured by ultraviolet/visible absorption spectrophotometry. As a result, no essential structural change of myoglobin was observed under 30oC, roughly equivalent to their body temperature, but the structure was clearly damaged at 40oC. The Soret band absorption hardly differed irrespective of preincubation temperature, suggesting that the structure around the heme pocket was not perturbed even after thermal treatment.

Keywords: denaturation, myoglobin, stability, tuna.

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510 Protective Effect of Thymoquinone against Nephrotoxicity Induced by Cadmium in Rats

Authors: Amr A. Fouad, Hamed A. Alwadaani, Iyad Jresat

Abstract:

The present study investigated the protective effect of thymoquinone (TQ), against cadmium-induced kidney injury in rats. Cadmium chloride (1.2 mg Cd/kg/day, s.c.), was given for nine weeks. TQ treatment (40 mg/kg/day, p.o.) started on the same day of cadmium administration and continued for nine weeks. TQ significantly decreased serum creatinine, renal malondialdehyde and nitric oxide, and significantly increased renal reduced glutathione in rats received cadmium. Histopathological examination showed that TQ markedly minimized renal tissue damage induced by cadmium. Immunohistochemical analysis revealed that TQ markedly decreased the cadmium-induced expression of inducible nitric oxide synthase, tumor necrosis factor-α, cyclooxygenase-2, and caspase-3 in renal tissue. It was concluded that TQ significantly protected against cadmium nephrotoxicity in rats, through its antioxidant, antiinflammatory, and antiapoptotic actions.

Keywords: Thymoquinone, cadmium, kidney, rats.

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