Search results for: performance measurement.
2413 Manipulation of Image Segmentation Using Cleverness Artificial Bee Colony Approach
Authors: Y. Harold Robinson, E. Golden Julie, P. Joyce Beryl Princess
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Image segmentation is the concept of splitting the images into several images. Image Segmentation algorithm is used to manipulate the process of image segmentation. The advantage of ABC is that it conducts every worldwide exploration and inhabitant exploration for iteration. Particle Swarm Optimization (PSO) and Evolutionary Particle Swarm Optimization (EPSO) encompass a number of search problems. Cleverness Artificial Bee Colony algorithm has been imposed to increase the performance of a neighborhood search. The simulation results clearly show that the presented ABC methods outperform the existing methods. The result shows that the algorithms can be used to implement the manipulator for grasping of colored objects. The efficiency of the presented method is improved a lot by comparing to other methods.Keywords: Color information, EPSO, ABC, image segmentation, particle swarm optimization, active contour, GMM.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 12912412 LQR and SMC Stabilization of a New Unmanned Aerial Vehicle
Authors: Kaan T. Oner, Ertugrul Cetinsoy, Efe Sirimoglu, Cevdet Hancer, Taylan Ayken, Mustafa Unel
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We present our ongoing work on the development of a new quadrotor aerial vehicle which has a tilt-wing mechanism. The vehicle is capable of take-off/landing in vertical flight mode (VTOL) and flying over long distances in horizontal flight mode. Full dynamic model of the vehicle is derived using Newton-Euler formulation. Linear and nonlinear controllers for the stabilization of attitude of the vehicle and control of its altitude have been designed and implemented via simulations. In particular, an LQR controller has been shown to be quite effective in the vertical flight mode for all possible yaw angles. A sliding mode controller (SMC) with recursive nature has also been proposed to stabilize the vehicle-s attitude and altitude. Simulation results show that proposed controllers provide satisfactory performance in achieving desired maneuvers.Keywords: UAV, VTOL, dynamic model, stabilization, LQR, SMC
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 21092411 An Analytical Framework for Multi-Site Supply Chain Planning Problems
Authors: Yin-Yann Chen
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As the gradual increase of the enterprise scale, the firms may possess many manufacturing plants located in different places geographically. This change will result in the multi-site production planning problems under the environment of multiple plants or production resources. Our research proposes the structural framework to analyze the multi-site planning problems. The analytical framework is composed of six elements: multi-site conceptual model, product structure (bill of manufacturing), production strategy, manufacturing capability and characteristics, production planning constraints, and key performance indicators. As well as the discussion of these six ingredients, we also review related literatures in this paper to match our analytical framework. Finally we take a real-world practical example of a TFT-LCD manufacturer in Taiwan to explain our proposed analytical framework for the multi-site production planning problems.Keywords: Multi-Site, Production Planning, Supply Chain, TFT-LCD.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19002410 Bridgeless Boost Power Factor Correction Rectifier with Hold-Up Time Extension Circuit
Authors: Chih-Chiang Hua, Yi-Hsiung Fang, Yuan-Jhen Siao
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A bridgeless boost (BLB) power factor correction (PFC) rectifier with hold-up time extension circuit is proposed in this paper. A full bridge rectifier is widely used in the front end of the ac/dc converter. Since the shortcomings of the full bridge rectifier, the bridgeless rectifier is developed. A BLB rectifier topology is utilized with the hold-up time extension circuit. Unlike the traditional hold-up time extension circuit, the proposed extension scheme uses fewer active switches to achieve a longer hold-up time. Simulation results are presented to verify the converter performance.Keywords: Bridgeless boost, boost converter, power factor correction, hold-up time.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 15162409 A Hybrid Recommender System based on Collaborative Filtering and Cloud Model
Authors: Chein-Shung Hwang, Ruei-Siang Fong
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User-based Collaborative filtering (CF), one of the most prevailing and efficient recommendation techniques, provides personalized recommendations to users based on the opinions of other users. Although the CF technique has been successfully applied in various applications, it suffers from serious sparsity problems. The cloud-model approach addresses the sparsity problems by constructing the user-s global preference represented by a cloud eigenvector. The user-based CF approach works well with dense datasets while the cloud-model CF approach has a greater performance when the dataset is sparse. In this paper, we present a hybrid approach that integrates the predictions from both the user-based CF and the cloud-model CF approaches. The experimental results show that the proposed hybrid approach can ameliorate the sparsity problem and provide an improved prediction quality.Keywords: Cloud model, Collaborative filtering, Hybridrecommender system
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19552408 Back Bone Node Based Black Hole Detection Mechanism in Mobile Ad Hoc Networks
Authors: Nidhi Gupta, Sanjoy Das, Khushal Singh
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Mobile Ad hoc Network is a set of self-governing nodes which communicate through wireless links. Dynamic topology MANETs makes routing a challenging task. Various routing protocols are there, but due to various fundamental characteristic open medium, changing topology, distributed collaboration and constrained capability, these protocols are tend to various types of security attacks. Black hole is one among them. In this attack, malicious node represents itself as having the shortest path to the destination but that path not even exists. In this paper, we aim to develop a routing protocol for detection and prevention of black hole attack by modifying AODV routing protocol. This protocol is able to detect and prevent the black hole attack. Simulation is done using NS-2, which shows the improvement in network performance.Keywords: Ad hoc, AODV, Back Bone, routing, Security.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 21602407 UWB Bowtie Slot Antenna for Breast Cancer Detection
Authors: N. Seladji-Hassaine, L. Merad, S.M. Meriah, F.T. Bendimerad
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UWB is a very attractive technology for many applications. It provides many advantages such as fine resolution and high power efficiency. Our interest in the current study is the use of UWB radar technique in microwave medical imaging systems, especially for early breast cancer detection. The Federal Communications Commission FCC allowed frequency bandwidth of 3.1 to 10.6 GHz for this purpose. In this paper we suggest an UWB Bowtie slot antenna with enhanced bandwidth. Effects of varying the geometry of the antenna on its performance and bandwidth are studied. The proposed antenna is simulated in CST Microwave Studio. Details of antenna design and simulation results such as return loss and radiation patterns are discussed in this paper. The final antenna structure exhibits good UWB characteristics and has surpassed the bandwidth requirements.Keywords: Ultra Wide Band (UWB), microwave imaging system, Bowtie antenna, return loss, impedance bandwidth enhancement.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 39782406 Ethnocentrism: The Hidden Adversary of Effective Global Leadership
Authors: Ruxandra A. Vodă
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With the industrial revolution, global leaders must more rapidly become knowledgeable of and develop essential cross-cultural competencies to be effective. Ethnocentrism represents a hidden barrier of effective leadership and must be acknowledged and addressed proactively by global leaders. The article examines the impact of ethnocentrism in four critical areas (leadership strategy, cross-cultural competencies, intercultural communication, and adaptation to international contexts) and argues that by developing cross-cultural competencies, leaders might naturally reduce ethnocentrism levels. This paper will also offer few examples to support international managers in understanding how ethnocentrism can affect performance.
Keywords: Adaptation to intercultural contexts, cross-cultural competencies, effective leadership, ethnocentrism, global leader, intercultural communication, leadership strategy, the GLOBE Project.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 6832405 An Evaluation Framework of Transportation Responsiveness: Case of Pattaya City
Authors: Wuttigrai Ngamsirijit, Yodmanee Tepanon
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Transportation is one of the main activities related to creating value for the tourists. Transport management in tourism mainly focuses on managing transfer points and vehicle capacity. However, transport service level must also be ensured as it now relates to tourist-s experiences. This paper emphasizes on the responsiveness as one of key service performance measures. An evaluation framework is developed and illustarted by using the case of small bus service in Pattaya city. It can be seen as a great potential for the city to utilize the small bus transportation in order to meet the needs of more diverse group of passengers and to support the expansion of tourist areas. The framework integrates with service operations management, logistics, and tourism behavior perspectives. The findings from the investigation of existing small bus service are presented and preliminarily validate the usability of the framework.Keywords: Responsiveness, Demand responsive transportation, Tourism, Logistics
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19162404 Improving Multi-storey Building Sensor Network with an External Hub
Authors: Malka N. Halgamuge, Toong-Khuan Chan, Priyan Mendis
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Monitoring and automatic control of building environment is a crucial application of Wireless Sensor Network (WSN) in which maximizing network lifetime is a key challenge. Previous research into the performance of a network in a building environment has been concerned with radio propagation within a single floor. We investigate the link quality distribution to obtain full coverage of signal strength in a four-storey building environment, experimentally. Our results indicate that the transitional region is of particular concern in wireless sensor network since it accommodates high variance unreliable links. The transitional region in a multi-storey building is mainly due to the presence of reinforced concrete slabs at each storey and the fac┬©ade which obstructs the radio signal and introduces an additional absorption term to the path loss.Keywords: Wireless sensor networks, radio propagation, building monitoring
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 15512403 Simulation of the Temperature and Heat Gain by Solar Parabolic Trough Collector in Algeria
Authors: M. Ouagued, A. Khellaf
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The objectif of the present work is to determinate the potential of the solar parabolic trough collector (PTC) for use in the design of a solar thermal power plant in Algeria. The study is based on a mathematical modeling of the PTC. Heat balance has been established respectively on the heat transfer fluid (HTF), the absorber tube and the glass envelop using the principle of energy conservation at each surface of the HCE cross-sectionn. The modified Euler method is used to solve the obtained differential equations. At first the results for typical days of two seasons the thermal behavior of the HTF, the absorber and the envelope are obtained. Then to determine the thermal performances of the heat transfer fluid, different oils are considered and their temperature and heat gain evolutions compared.Keywords: Direct solar irradiance, solar radiation in Algeria, solar parabolic trough collector, heat balance, thermal oil performance
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 36522402 Methanol Concentration Sensitive SWCNT/Nafion Composites
Authors: Kyongsoo Lee, , Seong-Il Kim, Byeong-Kwon Ju
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An aqueous methanol sensor for use in direct methanol fuel cells (DMFCs) applications is demonstrated; the methanol sensor is built using dispersed single-walled carbon nanotubes (SWCNTs) with Nafion117 solution to detect the methanol concentration in water. The study is aimed at the potential use of the carbon nanotubes array as a methanol sensor for direct methanol fuel cells (DMFCs). The concentration of methanol in the fuel circulation loop of a DMFC system is an important operating parameter, because it determines the electrical performance and efficiency of the fuel cell system. The sensor is also operative even at ambient temperatures and responds quickly to changes in the concentration levels of the methanol. Such a sensor can be easily incorporated into the methanol fuel solution flow loop in the DMFC system.Keywords: methanol concentration, SWCNT, nafion composites
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19282401 Balancing Neural Trees to Improve Classification Performance
Authors: Asha Rani, Christian Micheloni, Gian Luca Foresti
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In this paper, a neural tree (NT) classifier having a simple perceptron at each node is considered. A new concept for making a balanced tree is applied in the learning algorithm of the tree. At each node, if the perceptron classification is not accurate and unbalanced, then it is replaced by a new perceptron. This separates the training set in such a way that almost the equal number of patterns fall into each of the classes. Moreover, each perceptron is trained only for the classes which are present at respective node and ignore other classes. Splitting nodes are employed into the neural tree architecture to divide the training set when the current perceptron node repeats the same classification of the parent node. A new error function based on the depth of the tree is introduced to reduce the computational time for the training of a perceptron. Experiments are performed to check the efficiency and encouraging results are obtained in terms of accuracy and computational costs.Keywords: Neural Tree, Pattern Classification, Perceptron, Splitting Nodes.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 12252400 A Hybrid GMM/SVM System for Text Independent Speaker Identification
Authors: Rafik Djemili, Mouldi Bedda, Hocine Bourouba
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This paper proposes a novel approach that combines statistical models and support vector machines. A hybrid scheme which appropriately incorporates the advantages of both the generative and discriminant model paradigms is described and evaluated. Support vector machines (SVMs) are trained to divide the whole speakers' space into small subsets of speakers within a hierarchical tree structure. During testing a speech token is assigned to its corresponding group and evaluation using gaussian mixture models (GMMs) is then processed. Experimental results show that the proposed method can significantly improve the performance of text independent speaker identification task. We report improvements of up to 50% reduction in identification error rate compared to the baseline statistical model.Keywords: Speaker identification, Gaussian mixture model (GMM), support vector machine (SVM), hybrid GMM/SVM.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 22372399 Demand and Supply Chain Simulation in Telecommunication Industry by Multi-Rate Expert Systems
Authors: Andrus Pedai, Igor Astrov
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In modern telecommunications industry, demand & supply chain management (DSCM) needs reliable design and versatile tools to control the material flow. The objective for efficient DSCM is reducing inventory, lead times and related costs in order to assure reliable and on-time deliveries from manufacturing units towards customers. In this paper the multi-rate expert system based methodology for developing simulation tools that would enable optimal DSCM for multi region, high volume and high complexity manufacturing environment was proposed.Keywords: Demand & supply chain management, expert systems, inventory control, multi-rate control, performance metrics.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 18912398 Environmental Performance Assessment Model as a Sustainability Decision Tool for Small and Middle Sized Enterprises
Authors: Pavol Molnar, Martin Dolinsky
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Paper deals with environmental metrics and assessment systems devoted to Small and Medium Sized Enterprises. Authors are presenting proposed assessment model which has an ability to discover current environmental strengths and weaknesses of Small and Middle Sized Enterprise. Suggested model has also an ambition to become a Sustainability Decision Tool. Model is able to identify "best environmental devision" in the company, and to quantify how this decision contributed into overall environmental improvement. Authors understand environmental improvements as environmental innovations (product, process and organizational). Suggested model is based on its own concept; however, authors are also utilizing already existing environmental assessment tools.
Keywords: Corporate Social Responsibility, (e)IMPACT model, Environmental metrics, , Small and Middle Sized Enterprises
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 15362397 High Capacity Reversible Watermarking through Interpolated Error Shifting
Authors: Hae-Yeoun Lee
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Reversible watermarking that not only protects the copyright but also preserve the original quality of the digital content have been intensively studied. In particular, the demand for reversible watermarking has increased. In this paper, we propose a reversible watermarking scheme based on interpolation-error shifting and error pre-compensation. The intensity of a pixel is interpolated from the intensities of neighboring pixels, and the difference histogram between the interpolated and the original intensities is obtained and modified to embed the watermark message. By restoring the difference histogram, the embedded watermark is extracted and the original image is recovered by compensating for the interpolation error. The overflow and underflow are prevented by error pre-compensation. To show the performance of the method, the proposed algorithm is compared with other methods using various test images.
Keywords: Reversible watermarking, High capacity, High quality, Interpolated error shifting, Error pre-compensation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 22212396 State-Space PD Feedback Control
Authors: John Florescu
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A challenged control problem is when the performance is pushed to the limit. The state-derivative feedback control strategy directly uses acceleration information for feedback and state estimation. The derivative part is concerned with the rateof- change of the error with time. If the measured variable approaches the set point rapidly, then the actuator is backed off early to allow it to coast to the required level. Derivative action makes a control system behave much more intelligently. A sensor measures the variable to be controlled and the measured in formation is fed back to the controller to influence the controlled variable. A high gain problem can be also formulated for proportional plus derivative feedback transformation. Using MATLAB Simulink dynamic simulation tool this paper examines a system with a proportional plus derivative feedback and presents an automatic implementation of finding an acceptable controlled system. Using feedback transformations the system is transformed into another system.Keywords: Feedback, PD, state-space, derivative.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20232395 EHD Effect on the Dynamic Characteristics of a Journal Bearing Lubricated with Couple Stress Fluids
Authors: B. Chetti, W. A. Crosby
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This paper presents a numerical analysis for the dynamic performance of a finite journal bearing lubricated with couple stress fluid taking into account the effect of the deformation of the bearing liner. The modified Reynolds equation has been solved by using finite difference technique. The dynamic characteristics in terms of stiffness coefficients, damping coefficients, critical mass and whirl ratio are evaluated for different values of eccentricity ratio and elastic coefficient for a journal bearing lubricated with a couple stress fluids and a Newtonian fluid. The results show that the dynamic characteristics of journal bearings lubricated with couple stress fluids are improved compared to journal bearings lubricated with Newtonian fluids.
Keywords: Circular bearing, elastohydrodynamic, stability, couple stress.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 12692394 Extractive Fermentation of Ethanol Using Vacuum Fractionation Technique
Authors: Weeraya Samnuknit, Apichat Boontawan
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A vacuum fractionation technique was introduced to remove ethanol from fermentation broth. The effect of initial glucose and ethanol concentrations were investigated for specific productivity. The inhibitory ethanol concentration was observed at 100 g/L. In order to increase the fermentation performance, the ethanol product was removed as soon as it is produced. The broth was boiled at 35oC by reducing the pressure to 65 mBar. The ethanol/water vapor was fractionated for up to 90 wt% before leaving the column. Ethanol concentration in the broth was kept lower than 25 g/L, thus minimized the product inhibition effect to the yeast cells. For batch extractive fermentation, a high substrate utilization rate was obtained at 26.6 g/L.h and most of glucose was consumed within 21 h. For repeated-batch extractive fermentation, addition of glucose was carried out up to 9 times and ethanol was produced more than 8-fold higher than batch fermentation.
Keywords: Ethanol, Extractive fermentation, Product inhibition, Vacuum fractionation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 37932393 Study of the Effects of Ceramic Nano-Pigments in Cement Mortar Corrosion Caused by Chlorine Ions
Authors: R. Moradpour, S.B. Ahmadi, T. Parhizkar, M. Ghodsian, E. Taheri-Nassaj
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Superfine pigments that consist of natural and artificial pigments and are made of mineral soil with special characteristics are used in cementitious materials for various purposes. These pigments can decrease the amount of cement needed without loss of performance and strength and also change the monotonous and turbid colours of concrete into various attractive and light colours. In this study, the mechanical strength and resistance against chloride and halogen attacks of cement mortars containing ceramic nano-pigments in an affected environment are studied. This research suggests utilisation of ceramic nano-pigments between 50 and 1000 nm, obtaining full-depth coloured concrete, preventing chlorine penetration in the concrete up to a certain depth, and controlling corrosion in steel rebar with the Potentiostat (EG&G) apparatus.
Keywords: Nano-structures, Corrosion, Mechanical properties, Nano-pigments.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 28042392 Electrokinetic Remediation of Uranium Contaminated Soil by Ion Exchange Membranes
Authors: Z. H. Shi, T. J. Dou, H. Zhang, H. X. Huang, N. Zeng
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The contamination of significant quantities of soils and sediments with uranium and other actinide elements as a result of nuclear activity poses many environmental risks. The electrokinetic process is one of the most promising remediation techniques for sludge, sediment, and saturated or unsaturated soils contaminated with heavy metals and radionuclides. However, secondary waste is a major concern for soil contaminated with nuclides. To minimize the generation of secondary wastes, this study used the anion and cation exchange membranes to improve the performance of the experimental apparatus. Remediation experiments of uranium-contaminated soil were performed with different agents. The results show that using acetic acid and EDTA as chelating agents clearly enhances the migration ability of the uranium. The ion exchange membranes (IEMs) used in the experiments not only reduce secondary wastes, but also, keep the soil pH stable.Keywords: Electrokinetic remediation, ion exchange membranes, soil, uranium.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 13982391 A Generator from Cascade Markov Model for Packet Loss and Subsequent Bit Error Description
Authors: Jaroslav Polec, Viliam Hirner, Michal Martinovič, Kvetoslava Kotuliaková
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In this paper we present a novel error model for packet loss and subsequent error description. The proposed model simulates the error performance of wireless communication link. The model is designed as two independent Markov chains, where the first one is used for packet generation and the second one generates correctly and incorrectly transmitted bits for received packets from the first chain. The statistical analyses of real communication on the wireless link are used for determination of model-s parameters. Using the obtained parameters and the implementation of the generator, we collected generated traffic. The obtained results generated by proposed model are compared with the real data collection.Keywords: Wireless channel, error model, Markov chain, Elliot model, Gilbert model, generator, IEEE 802.11.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 21132390 Nonlinear Adaptive PID Control for a Semi-Batch Reactor Based On an RBF Network
Authors: Magdi M. Nabi, Ding-Li Yu
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Control of a semi-batch polymerization reactor using an adaptive radial basis function (RBF) neural network method is investigated in this paper. A neural network inverse model is used to estimate the valve position of the reactor; this method can identify the controlled system with the RBF neural network identifier. The weights of the adaptive PID controller are timely adjusted based on the identification of the plant and self-learning capability of RBFNN. A PID controller is used in the feedback control to regulate the actual temperature by compensating the neural network inverse model output. Simulation results show that the proposed control has strong adaptability, robustness and satisfactory control performance and the nonlinear system is achieved.
Keywords: Chylla-Haase polymerization reactor, RBF neural networks, feed-forward and feedback control.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 26762389 Comparison of Different Data Acquisition Techniques for Shape Optimization Problems
Authors: Attila Vámosi, Tamás Mankovits, Dávid Huri, Imre Kocsis, Tamás Szabó
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Non-linear FEM calculations are indispensable when important technical information like operating performance of a rubber component is desired. For example rubber bumpers built into air-spring structures may undergo large deformations under load, which in itself shows non-linear behavior. The changing contact range between the parts and the incompressibility of the rubber increases this non-linear behavior further. The material characterization of an elastomeric component is also a demanding engineering task. The shape optimization problem of rubber parts led to the study of FEM based calculation processes. This type of problems was posed and investigated by several authors. In this paper the time demand of certain calculation methods are studied and the possibilities of time reduction is presented.
Keywords: Rubber bumper, data acquisition, finite element analysis, support vector regression.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 21482388 Investigation of Genetic Epidemiology of Metabolic Compromises in ß Thalassemia Minor Mutation: Phenotypic Pleiotropy
Authors: Surajit Debnath, Soma Addya
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Human genome is not only the evolutionary summation of all advantageous events, but also houses lesions of deleterious foot prints. A single gene mutation sometimes may express multiple consequences in numerous tissues and a linear relationship of the genotype and the phenotype may often be obscure. ß Thalassemia minor, a transfusion independent mild anaemia, coupled with environment among other factors may articulate into phenotypic pleotropy with Hypocholesterolemia, Vitamin D deficiency, Tissue hypoxia, Hyper-parathyroidism and Psychological alterations. Occurrence of Pancreatic insufficiency, resultant steatorrhoea, Vitamin-D (25-OH) deficiency (13.86 ngm/ml) with Hypocholesterolemia (85mg/dl) in a 30 years old male ß Thal-minor patient (Hemoglobin 11mg/dl with Fetal Hemoglobin 2.10%, Hb A2 4.60% and Hb Adult 84.80% and altered Hemogram) with increased Para thyroid hormone (62 pg/ml) & moderate Serum Ca+2 (9.5mg/ml) indicate towards a cascade of phenotypic pleotropy where the ß Thalassemia mutation ,be it in the 5’ cap site of the mRNA , differential splicing etc in heterozygous state is effecting several metabolic pathways. Compensatory extramedulary hematopoiesis may not coped up well with the stressful life style of the young individual and increased erythropoietic stress with high demand for cholesterol for RBC membrane synthesis may have resulted in Hypocholesterolemia.Oxidative stress and tissue hypoxia may have caused the pancreatic insufficiency, leading to Vitamin D deficiency. This may in turn have caused the secondary hyperparathyroidism to sustain serum Calcium level. Irritability and stress intolerance of the patient was a cumulative effect of the vicious cycle of metabolic compromises. From these findings we propose that the metabolic deficiencies in the ß Thalassemia mutations may be considered as the phenotypic display of the pleotropy to explain the genetic epidemiology. According to the recommendations from the NIH Workshop on Gene-Environment Interplay in Common Complex Diseases: Forging an Integrative Model, study design of observations should be informed by gene-environment hypotheses and results of a study (genetic diseases) should be published to inform future hypotheses. Variety of approaches is needed to capture data on all possible aspects, each of which is likely to contribute to the etiology of disease. Speakers also agreed that there is a need for development of new statistical methods and measurement tools to appraise information that may be missed out by conventional method where large sample size is needed to segregate considerable effect. A meta analytic cohort study in future may bring about significant insight on to the title comment.Keywords: Genetic disease, Genetic epidemiology, Heterozygous, Phenotype, Pleotropy, ß Thalassemia minor, Metabolic compromises.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 65652387 Stack Ventilation for an Office Building with a Multi-Story Atrium
Authors: Karina Natali, Wei-Hwa Chiang
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This study examines the stack ventilation performance of an office building located in Taipei, Taiwan. Atriums in this building act as stacks that facilitate buoyancy-driven ventilation. Computational Fluid Dynamic (CFD) simulations are used to identify interior airflow patterns, and then used these patterns to assess the building’s heat expulsion efficiency. Ambient temperatures of 20°C were adopted as the typical seasonal spring temperature range in Taipei. Further, “zero-wind” conditions are established to ensure simulation results reflected only the buoyancy effect. After checking results against neutral pressure level (NPL) level, airflow, air velocity, and indoor temperature stratification, the lower stack is modified to reduce the NPL in order to remove heat accumulated on the top floor.
Keywords: Natural ventilation, side outlet, stack effect, thermal comfort.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20032386 Loss Reduction and Reliability Improvement of Industrial Distribution System through Network Reconfiguration
Authors: Ei Ei Phyu, Kyaw Myo Lin, Thin Thin Moe
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The paper presents an approach to improve the reliability and reduce line losses of practical distribution system applying network reconfiguration. The change of the topology redirects the power flow within the distribution network to obtain better performance of the system. Practical distribution network (Pyigyitagon Industrial Zone (I)) is used as the case study network. The detailed calculations of the reliability indices are done by using analytical method and power flow calculation is performed by Newton-Rephason solver. The comparison of various network reconfiguration techniques are described with respect to power loss and reliability index levels. Finally, the optimal reconfigured network is selected among difference cases based on the two factors: the most reliable network and the least loss minimization.
Keywords: Distribution system reliability, loss reduction, network reconfiguration, reliability enhancement, reliability indices.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 8872385 Piezoelectric Approach on Harvesting Acoustic Energy
Authors: Khin Fai Chen, Jee-Hou Ho, Eng Hwa Yap
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An Acoustic Micro-Energy Harvester (AMEH) is developed to convert wasted acoustical energy into useful electrical energy. AMEH is mathematically modeled using Lumped Element Modelling (LEM) and Euler-Bernoulli beam (EBB) modelling. An experiment is designed to validate the mathematical model and assess the feasibility of AMEH. Comparison of theoretical and experimental data on critical parameter value such as Mm, Cms, dm and Ceb showed the variances are within 1% to 6%, which is reasonably acceptable. Then, AMEH undergoes bandwidth tuning for performance optimization. The AMEH successfully produces 0.9V/(m/s^2) and 1.79μW/(m^2/s^4) at 60Hz and 400kΩ resistive load which only show variances about 7% compared to theoretical data. At 1g and 60Hz resonance frequency, the averaged power output is about 2.2mW which fulfilled a range of wireless sensors and communication peripherals power requirements. Finally, the design for AMEH is assessed, validated and deemed as a feasible design.Keywords: Piezoelectric, acoustic, energy harvester, thermoacoustic.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 32732384 Low Power CNFET SRAM Design
Authors: Pejman Hosseiniun, Rose Shayeghi, Iman Rahbari, Mohamad Reza Kalhor
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CNFET has emerged as an alternative material to silicon for high performance, high stability and low power SRAM design in recent years. SRAM functions as cache memory in computers and many portable devices. In this paper, a new SRAM cell design based on CNFET technology is proposed. The proposed SRAM cell design for CNFET is compared with SRAM cell designs implemented with the conventional CMOS and FinFET in terms of speed, power consumption, stability, and leakage current. The HSPICE simulation and analysis show that the dynamic power consumption of the proposed 8T CNFET SRAM cell’s is reduced about 48% and the SNM is widened up to 56% compared to the conventional CMOS SRAM structure at the expense of 2% leakage power and 3% write delay increase.
Keywords: SRAM cell, CNFET, low power, HSPICE.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2703