Search results for: nanoparticle diameter
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 626

Search results for: nanoparticle diameter

386 One-Pot Synthesis and Characterization of Magnesium Oxide Nanoparticles Prepared by Calliandra calothyrsus Leaf Extract

Authors: Indah Kurniawaty, Yoki Yulizar, Haryo Satrya Oktaviano, Adam Kusuma Rianto

Abstract:

Magnesium oxide nanoparticles (MgO NP) were successfully synthesized in this study using a one-pot green synthesis mediated by Calliandra calothyrsus leaf extract (CLE). CLE was prepared by maceration of the leaf using methanol with a ratio of 1:5 for 7 days. Secondary metabolites in CLE, such as alkaloids and flavonoids, served as a weak base provider and capping agent in the formation of MgO NP. CLE Fourier Transform Infra-Red (FTIR) spectra peak at 3255 cm-1, 1600 cm-1, 1384 cm-1, 1205 cm-1, 1041 cm-1, and 667 cm-1 showing the presence of vibrations O-H stretching, N-H bending, C-C stretching, C-N stretching and N-H wagging. During the experiment, different CLE volumes and calcined temperatures were used, resulting in a variety of structures. Energy Dispersive X-ray Spectrometer (EDS) and FTIR were used to characterize metal oxide particles. MgO diffraction patterns at 2θ of 36.9°; 42.9°; 62.2°; 74.6°; and 78.5° can be assigned to crystal planes (111), (200), (220), (311), and (222), respectively. Scanning Electron Microscopy (SEM) was used to characterize the surface morphology. The morphology ranged from sphere to flower-like resulting in crystallite sizes of 28 nm, 23 nm, 12 nm, and 9 nm.

Keywords: Calliandra calothyrsus, green-synthesis, magnesium oxide, nanoparticle.

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385 Nanobiocomposites with Enhanced Cell Proliferation and Improved Mechanical Properties Based on Organomodified-Nanoclay and Silicone Rubber

Authors: M. S. Hosseini, M. Tazzoli-Shadpour, I. Amjadi, A. A. Katbab, E. Jaefargholi-Rangraz

Abstract:

Bionanotechnology deals with nanoscopic interactions between nanostructured materials and biological systems. Polymer nanocomposites with optimized biological activity have attracted great attention. Nanoclay is considered as reinforcing nanofiller in manufacturing of high performance nanocomposites. In current study, organomodified-nanoclay with negatively charged silicate layers was incorporated into biomedical grade silicone rubber. Nanoparticle loading has been tailored to enhance cell behavior. Addition of nanoparticles led to improved mechanical properties of substrate with enhanced strength and stiffness while no toxic effects was observed. Results indicated improved viability and proliferation of cells by addition of nanofillers. The improved mechanical properties of the matrix result in proper cell response through adjustment and arrangement of cytoskeletal fibers. Results can be applied in tissue engineering when enhanced substrates are required for improvement of cell behavior for in vivo applications.

Keywords: Biocompatibility, Composite, Organomodified- Nanoclay, Proliferation

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384 Machining of FRP Composites by Abrasive Jet Machining Optimization Using Taguchi

Authors: D. V. Srikanth, M. Sreenivasa Rao

Abstract:

Abrasive Jet Machining is an Unconventional machining process in which the metal is removed from brittle and hard material in the form of micro-chips. With increase in need of materials like ceramics, composites, in manufacturing of various Mechanical & Electronic components, AJM has become a useful technique for micro machining. The present study highlights the influence of different parameters like Pressure, SOD, Time, Abrasive grain size, nozzle diameter on the Metal removal of FRP (Fiber Reinforced Polymer) composite by Abrasive jet machining. The results of the Experiments conducted were analyzed and optimized with TAGUCHI method of Optimization and ANOVA for Optimal Value.

Keywords: ANOVA, FRP Composite, AJC.

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383 Fluorescence Spectroscopy of Lysozyme-Silver Nanoparticles Complex

Authors: S. Ashrafpour, T. Tohidi Moghadam, B. Ranjbar

Abstract:

Identifying the nature of protein-nanoparticle interactions and favored binding sites is an important issue in functional characterization of biomolecules and their physiological responses. Herein, interaction of silver nanoparticles with lysozyme as a model protein has been monitored via fluorescence spectroscopy. Formation of complex between the biomolecule and silver nanoparticles (AgNPs) induced a steady state reduction in the fluorescence intensity of protein at different concentrations of nanoparticles. Tryptophan fluorescence quenching spectra suggested that silver nanoparticles act as a foreign quencher, approaching the protein via this residue. Analysis of the Stern-Volmer plot showed quenching constant of 3.73 μM−1. Moreover, a single binding site in lysozyme is suggested to play role during interaction with AgNPs, having low affinity of binding compared to gold nanoparticles. Unfolding studies of lysozyme showed that complex of lysozyme- AgNPs has not undergone structural perturbations compared to the bare protein. Results of this effort will pave the way for utilization of sensitive spectroscopic techniques for rational design of nanobiomaterials in biomedical applications.

Keywords: Nanocarrier, Nanoparticles, Surface Plasmon Resonance, Quenching Fluorescence.

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382 Effect of Particle Size in Aviation Turbine Fuel-Al2O3 Nanofluids for Heat Transfer Applications

Authors: Sandipkumar Sonawane, Upendra Bhandarkar, Bhalchandra Puranik, S. Sunil Kumar

Abstract:

The effect of Alumina nanoparticle size on thermophysical properties, heat transfer performance and pressure loss characteristics of Aviation Turbine Fuel (ATF)-Al2O3 nanofluids is studied experimentally for the proposed application of regenerative cooling of semi-cryogenic rocket engine thrust chambers. Al2O3 particles with mean diameters of 50 nm or 150 nm are dispersed in ATF. At 500C and 0.3% particle volume concentration, the bigger particles show increases of 17% in thermal conductivity and 55% in viscosity, whereas the smaller particles show corresponding increases of 21% and 22% for thermal conductivity and viscosity respectively. Contrary to these results, experiments to study the heat transfer performance and pressure loss characteristics show that at the same pumping power, the maximum enhancement in heat transfer coefficient at 500C and 0.3% concentration is approximately 47% using bigger particles, whereas it is only 36% using smaller particles.

Keywords: Heat transfer performance, Nanofluids, Thermalconductivity, Viscosity

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381 La promoted Ni/α-Al2O3 Catalysts for Syngas Methanation

Authors: Anmin Zhao, Weiyong Yingı , Haitao Zhang, Hongfang Ma, Dingye Fang

Abstract:

The Ni/α-Al2O3 catalysts with different amounts of La as promoter from 0 to 4 wt % were prepared, characterized and their catalytic activity was investigated in syngas methanation reaction. Effects of reaction temperature and lanthanum loading on carbon oxides conversion and methane selectivity were also studied. Adding certain amount of lanthanum to 10Ni /α-Al2O3 catalysts can decrease the average NiO crystallite diameter which leads to higher activity and stability while excessive addition would cause deactivation quickly. Stability on stream towards deactivation was observed up to 800 min at 500 °C, 0.1MPa and 600000 mL·g-1·h-1.

Keywords: Methanation; Nickel catalysts; Syngas methanation

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380 Minaret of Medieval City Aktobe

Authors: Yeraly Akymbek, Beibit Baibugunov

Abstract:

In the article the remains of the base of the minaret, found in 2009 at the medieval fortress shakhristan Aktobe, which is located along the courses of the rivers Balta and Aksu. The minaret, which consists of two parts: the stylobate in the pit and base part refers to the XI-XII centuries. The preserved height of the building is 3.6 meters. Volume stylobat quadrangular minaret, the corners of which are aimed at the four corners of the world amounts to 8,65 x8, 5 m, height – 2.6 m. Diameter octagonal upper cap of 7.85 m and a height of preserved – 1 m. This minaret is of particular importance among the historical and architectural monuments of Kazakhstan, as it is so far the only minaret belonging to Karakhanid epoch in which Islam was the state religion.

Keywords: Aktobe, medieval, minaret, stylobate.

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379 Evaluation of Tension Capacity of Pile (Case Study in Sandy Soil)

Authors: Shooshpasha I., Kiakojoori M., Mirzagoltabar R. A.

Abstract:

High building constructions are increasing in south beaches of the Caspian Sea because of tourist attractions and limitation of residential areas. According to saturated alluvial fields transfer of load from high structures to the soil by piles is inevitable. In spite of most of these piles are under compression forces, tension piles are used in special conditions. Few studies have been conducted because of the limited use of these piles. Tension capacity of openended pipe piles in full scale was tested in this study. The length of the bored piles was 420 up to 480 cm and all were in 120 cm diameter. The results of testing 7 piles were compared with the results of relations given by researches.

Keywords: piles, tension capacity, sand, shaft friction

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378 Heat Transfer from Two Cam Shaped Cylinders in Side-by-Side Arrangement

Authors: Arash Mir Abdolah Lavasani, Hamidreza Bayat

Abstract:

Heat transfer from two cam shape cylinder in side-byside arrangement had been studied numerically. The transverse gap between the centers of cylinders (T) is allowed to vary to change the pitch ratio (T/Deq). The equivalent diameter of the cylinder (Deq) is 27.6 mm and pitch ratio varies in range of 1≤T/Deq≤3. The Reynolds numbers based on equivalent circular cylinder are within 50≤ Reeq≤150. Results show that Nusselt number of cylinders increases about 1 to 36 percent when pitch ratio increases from 1 to 3.

Keywords: Cam shaped, side-by-side cylinders, numerical, heat Transfer.

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377 MHD Non-Newtonian Nanofluid Flow over a Permeable Stretching Sheet with Heat Generation and Velocity Slip

Authors: Rama Bhargava, Mania Goyal

Abstract:

The problem of magnetohydrodynamics boundary layer flow and heat transfer on a permeable stretching surface in a second grade nanofluid under the effect of heat generation and partial slip is studied theoretically. The Brownian motion and thermophoresis effects are also considered. The boundary layer equations governed by the PDE’s are transformed into a set of ODE’s with the help of local similarity transformations. The differential equations are solved by variational finite element method. The effects of different controlling parameters on the flow field and heat transfer characteristics are examined. The numerical results for the dimensionless velocity, temperature and nanoparticle volume fraction as well as the reduced Nusselt and Sherwood number have been presented graphically. The comparison confirmed excellent agreement. The present study is of great interest in coating and suspensions, cooling of metallic plate, oils and grease, paper production, coal water or coal-oil slurries, heat exchangers technology, materials processing exploiting.

Keywords: Viscoelastic nanofluid, partial slip, stretching sheet, heat generation/absorption, MHD flow, FEM.

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376 Zero Divisor Graph of a Poset with Respect to Primal Ideals

Authors: Hossein Pourali

Abstract:

In this paper, we extend the concepts of primal and weakly primal ideals for posets. Further, the diameter of the zero divisor graph of a poset with respect to a non-primal ideal is determined. The relation between primary and primal ideals in posets is also studied.

Keywords: Zero divisors graph, ideal, prime ideal, semiprime ideal, primal ideal, weakly primal ideal, associated prime ideal, primary ideal.

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375 Characterization and Detection of Cadmium Ion Using Modification Calixarene with Multiwalled Carbon Nanotubes

Authors: Amira Shakila Razali, Faridah Lisa Supian, Muhammad Mat Salleh, Suraini Abu Bakar

Abstract:

Water contamination by toxic compound is one of the serious environmental problems today. These toxic compounds mostly originated from industrial effluents, agriculture, natural sources and human waste. These studies focus on modification of multiwalled carbon nanotube (MWCNTs) with nanoparticle of calixarene and explore the possibility of using this modification for the remediation of cadmium in water. The nanocomposites were prepared by dissolving calixarene in chloroform solution as solvent, followed by additional multiwalled carbon nanotube (MWCNTs) then sonication process for 3 hour and fabricated the nanocomposites on substrate by spin coating method. Finally, the nanocomposites were tested on cadmium ion (10 mg/ml). The morphology of nanocomposites was investigated by FESEM showing the formation of calixarene on the outer walls of carbon nanotube and cadmium ion also clearly seen from the micrograph. This formation was supported by using energy dispersive x-ray (EDX). The presence of cadmium ions in the films, leads to some changes in the surface potential and Fourier Transform Infrared spectroscopy (FTIR).The nanocomposites MWCNTs-calixarene have potential for development of sensor for pollutant monitoring and nanoelectronics devices applications.

Keywords: Calixarene, Multiwalled Carbon Nanotubes, Cadmium, Surface Potential.

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374 Some Physical Properties of Musk Lime (Citrus Microcarpa)

Authors: M.H.R.O. Abdullah, P.E. Ch'ng, N.A. Yunus

Abstract:

Some physical properties of musk lime (Citrus microcarpa) were determined in this study. The average moisture content (wet basis) of the fruit was found to be 85.10 (±0.72) %. The mean of length, width and thickness of the fruit was 26.36 (±0.97), 26.40 (±1.04) and 25.26 (±0.94) mm respectively. The average value for geometric mean diameter, sphericity, aspect ratio, mass, surface area, volume, true density, bulk density and porosity was 26.00 (±0.82) mm, 98.67 (±2.04) %, 100.23 (±3.28) %, 10.007 (±0.878) g, 2125.07 (±133.93) mm2, 8800.00 (±731.82) mm3, 1002.87 (±39.16) kgm-3, 501.70 (±22.58) kgm-3 and 49.89 (±3.15) % respectively. The coefficient of static friction on four types of structural surface was found to be varying from 0.238 (±0.025) for glass to 0.247 (±0.024) for steel surface.

Keywords: Musk lime, Citrus microcarpa, physical properties.

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373 Streamwise Conduction of Nanofluidic Flow in Microchannels

Authors: Yew Mun Hung, Ching Sze Lim, Tiew Wei Ting, Ningqun Guo

Abstract:

The effect of streamwise conduction on the thermal characteristics of forced convection for nanofluidic flow in rectangular microchannel heat sinks under isothermal wall has been investigated. By applying the fin approach, models with and without streamwise conduction term in the energy equation were developed for hydrodynamically and thermally fully-developed flow. These two models were solved to obtain closed form analytical solutions for the nanofluid and solid wall temperature distributions and the analysis emphasized details of the variations induced by the streamwise conduction on the nanofluid heat transport characteristics. The effects of the Peclet number, nanoparticle volume fraction, thermal conductivity ratio on the thermal characteristics of forced convection in microchannel heat sinks are analyzed. Due to the anomalous increase in the effective thermal conductivity of nanofluid compared to its base fluid, the effect of streamwise conduction is expected to be more significant. This study reveals the significance of the effect of streamwise conduction under certain conditions of which the streamwise conduction should not be neglected in the forced convective heat transfer analysis of microchannel heat sinks.

Keywords: fin approach, microchannel heat sink, nanofluid, streamwise conduction

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372 Numerical Study of Flow around Flat Tube between Parallel Walls

Authors: Hamidreza Bayat, Arash Mirabdolah Lavasani, Meysam Bolhasani, Sajad Moosavi

Abstract:

Flow around a flat tube is studied numerically. Reynolds number is defined base on equivalent circular tube and it is varied in range of 100 to 300. Equations are solved by using finite volume method and results are presented in form of drag and lift coefficient. Results show that drag coefficient of flat tube is up to 66% lower than circular tube with equivalent diameter. In addition, by increasing l/D from 1 to 2, the drag coefficient of flat tube is decreased about 14-27%.

Keywords: Laminar flow, flat-tube, drag coefficient, cross-flow, heat exchanger.

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371 Distributor Plate Design and a System for Collection of Granules in a Device with a Vortex Fluidized Bed

Authors: Bogdan Il. Bogdanov, Dimitar R.Rusev, Yancho H. Hristov, Irena G. Markovska, Dimitar P.Georgiev

Abstract:

A newly designed gas-distributor for granulation of powdery materials in equilibrated fluidized bed and a system for collecting the granules prepared are suggested. The aim of these designs is to solve the problems arising by the granulation of powdery materials in fluidized bed devices. The gasdistributor and the collection system proved to be reliable at operation; they reduce the size of still zones, effectively disperse the binding solution in the bed and ensure the collection of granules of given diameter

Keywords: Distributor plate design, granulation, system design.

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370 Preparation and Characterization of Self Assembled Gold Nanoparticles on Amino Functionalized SiO2 Dielectric Core

Authors: M.E.khosroshahi , M.S.Nourbakhsh

Abstract:

Wet chemistry methods are used to prepare the SiO2/Au nanoshells. The purpose of this research was to synthesize gold coated SiO2 nanoshells for biomedical applications. Tunable nanoshells were prepared by using different colloidal concentrations. The nanoshells are characterized by FTIR, XRD, UV-Vis spectroscopy and atomic force microscopy (AFM). The FTIR results confirmed the functionalization of the surfaces of silica nanoparticles with NH2 terminal groups. A tunable absorption was observed between 470-600 nm with a maximum range of 530-560 nm. Based on the XRD results three main peaks of Au (111), (200) and (220) were identified. Also AFM results showed that the silica core diameter was about 100 nm and the thickness of gold shell about 10 nm.

Keywords: Gold nanoshells, Synthesis, UV-vis spectroscopy, XRD, AFM

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369 A New Correlation for Overall Sherwood Number in Packed Liquid-Liquid Extraction Column

Authors: S. GhaffariTooran, H. Abolghasemi, H. Bahmanyar, M. Esmaeili, A. Safari

Abstract:

Using plug flow model in conjunction with experimental solute concentration profiles, overall volumetric mass transfer coefficient based on continuous phase (Koca), in a packed liquid-liquid extraction column has been optimized. Number of 12 experiments has been done using standard system of water/acid acetic/toluene in a 6 cm diameter, 120 cm height column. Thorough consideration of influencing parameters we intended to correlate dimensionless parameters in term of overall Sherwood number which has an acceptable average error of about 15.8%.

Keywords: Packed column, mass transfer coefficient, solvent extraction, Sherwood number.

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368 Characteristics of Turbulent Round Jets in its Potential-Core Region

Authors: S. Sivakumar, Ravikiran Sangras, Vasudevan Raghavan

Abstract:

In this work, stationary hot-wire measurements are carried out to investigate the characteristics of a round free jet in its potential core region (0 ≤ x/d ≤ 10). Measurements are carried out on an incompressible round jet for a range of Reynolds numbers from 4000 to 8000, calculated based on the jet exit mean velocity and the nozzle diameter. The effect of flow velocity on the development characteristics of the jet in the core region is analyzed. Timeaveraged statistics, spectra of velocity and its higher order moments are presented and explained.

Keywords: Contoured nozzle, hot-wire anemometer, Reynolds number, velocity fluctuations, velocity spectra.

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367 Fe3O4 and Fe3O4@Au Nanoparticles: Synthesis and Functionalisation for Biomolecular Attachment

Authors: Hendriëtte van der Walt, Lesley Chown, Richard Harris, Ndabenhle Sosibo, Robert Tshikhudo

Abstract:

The use of magnetic and magnetic/gold core/shell nanoparticles in biotechnology or medicine has shown good promise due to their hybrid nature which possesses superior magnetic and optical properties. Some of these potential applications include hyperthermia treatment, bio-separations, diagnostics, drug delivery and toxin removal. Synthesis refinement to control geometric and magnetic/optical properties, and finding functional surfactants for biomolecular attachment, are requirements to meet application specifics. Various high-temperature preparative methods were used for the synthesis of iron oxide and gold-coated iron oxide nanoparticles. Different surface functionalities, such as 11-aminoundecanoic and 11-mercaptoundecanoic acid, were introduced on the surface of the particles to facilitate further attachment of biomolecular functionality and drug-like molecules. Nanoparticle thermal stability, composition, state of aggregation, size and morphology were investigated and the results from techniques such as Fourier Transform-Infra Red spectroscopy (FT-IR), Ultraviolet visible spectroscopy (UV-vis), Transmission Electron Microscopy (TEM) and thermal analysis are discussed.

Keywords: Core/shell, Iron oxide, Gold coating, Nanoparticles.

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366 Stability Analysis of Three-Dimensional Flow and Heat Transfer over a Permeable Shrinking Surface in a Cu-Water Nanofluid

Authors: Roslinda Nazar, Amin Noor, Khamisah Jafar, Ioan Pop

Abstract:

In this paper, the steady laminar three-dimensional boundary layer flow and heat transfer of a copper (Cu)-water nanofluid in the vicinity of a permeable shrinking flat surface in an otherwise quiescent fluid is studied. The nanofluid mathematical model in which the effect of the nanoparticle volume fraction is taken into account is considered. The governing nonlinear partial differential equations are transformed into a system of nonlinear ordinary differential equations using a similarity transformation which is then solved numerically using the function bvp4c from Matlab. Dual solutions (upper and lower branch solutions) are found for the similarity boundary layer equations for a certain range of the suction parameter. A stability analysis has been performed to show which branch solutions are stable and physically realizable. The numerical results for the skin friction coefficient and the local Nusselt number as well as the velocity and temperature profiles are obtained, presented and discussed in detail for a range of various governing parameters.

Keywords: Heat Transfer, Nanofluid, Shrinking Surface, Stability Analysis, Three-Dimensional Flow.

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365 A Systematic Approach for Finding Hamiltonian Cycles with a Prescribed Edge in Crossed Cubes

Authors: Jheng-Cheng Chen, Chia-Jui Lai, Chang-Hsiung Tsai,

Abstract:

The crossed cube is one of the most notable variations of hypercube, but some properties of the former are superior to those of the latter. For example, the diameter of the crossed cube is almost the half of that of the hypercube. In this paper, we focus on the problem embedding a Hamiltonian cycle through an arbitrary given edge in the crossed cube. We give necessary and sufficient condition for determining whether a given permutation with n elements over Zn generates a Hamiltonian cycle pattern of the crossed cube. Moreover, we obtain a lower bound for the number of different Hamiltonian cycles passing through a given edge in an n-dimensional crossed cube. Our work extends some recently obtained results.

Keywords: Interconnection network, Hamiltonian, crossed cubes, prescribed edge.

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364 Investigation on Polymer Based Nano-Silver as Food Packaging Materials

Authors: A. M. Metak, T. T. Ajaal

Abstract:

Commercial nanocomposite food packaging type nano-silver containers were characterised using scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX). The presence of nanoparticles consistent with the incorporation of 1% nano-silver (Ag) and 0.1% titanium dioxide (TiO2) nanoparticle into polymeric materials formed into food containers was confirmed. Both nanomaterials used in this type of packaging appear to be embedded in a layered configuration within the bulk polymer. The dimensions of the incorporated nanoparticles were investigated using X-ray diffraction (XRD) and determined by calculation using the Scherrer Formula; these were consistent with Ag and TiO2 nanoparticles in the size range 20-70nm both were spherical shape nanoparticles. Antimicrobial assessment of the nanocomposite container has also been performed and the results confirm the antimicrobial activity of Ag and TiO2 nanoparticles in food packaging containers. Migration assessments were performed in a wide range of food matrices to determine the migration of nanoparticles from the packages. The analysis was based upon the relevant European safety Directives and involved the application of inductively coupled plasma mass spectrometry (ICP-MS) to identify the range of migration risk. The data pertain to insignificance levels of migration of Ag and TiO2 nanoparticles into the selected food matrices.

Keywords: Nano-silver, antimicrobial food packaging, migration, titanium dioxide.

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363 Measurement of Reverse Flow Generated at Cold Exit of Vortex Tube

Authors: Mohd Hazwan bin Yusof, Hiroshi Katanoda

Abstract:

In order to clarify the structure of the cold flow discharged from the vortex tube (VT), the pressure of the cold flow was measured, and a simple flow visualization technique using a 0.75mm-diameter needle and an oily paint is made to study the reverse flow at the cold exit. It is clear that a negative pressure and positive pressure region exist at a certain pressure and cold fraction area, and that a reverse flow is observed in the negative pressure region.

Keywords: Flow visualization, Pressure measurement, Reverse flow, Vortex tube.

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362 Conductivity and Selection of Copper Clad Steel Wires for Grounding Applications

Authors: George Eduful, Kingsford J. A. Atanga

Abstract:

Copper clad steel wire (CCS) is primarily used for grounding applications to reduce the high incidence of copper ground conductor theft in electrical installations. The cross sectional area of the CCS is selected by relating the diameter equivalence to a copper conductor. The main difficulty is how to use a simple analytical relation to determine the right conductivity of CCS for a particular application. The use of Eddy-Current instrument for measuring conductivity is known but in most cases, the instrument is not readily available. The paper presents a simplified approach on how to size and determine CCS conductivity for a given application.

Keywords: Copper clad steel wire, conductivity, grounding, skin effect.

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361 Resveratrol Incorporated Liposomes Prepared from Pegylated Phospholipids and Cholesterol

Authors: Mont Kumpugdee-Vollrath, Khaled Abdallah

Abstract:

Liposomes and pegylated liposomes were widely used as drug delivery system in pharmaceutical field since a long time. However, in the former time, polyethylene glycol (PEG) was connected into phospholipid after the liposomes were already prepared. In this paper, we intend to study the possibility of applying phospholipids which already connected with PEG and then they were used to prepare liposomes. The model drug resveratrol was used because it can be applied against different diseases. Cholesterol was applied to stabilize the membrane of liposomes. The thin film technique in a laboratory scale was a preparation method. The liposomes were then characterized by nanoparticle tracking analysis (NTA), photon correlation spectroscopy (PCS) and light microscopic techniques. The stable liposomes can be produced and the particle sizes after filtration were in nanometers. The 2- and 3-chains-PEG-phospholipid (PL) caused in smaller particle size than the 4-chains-PEG-PL. Liposomes from PL 90G and cholesterol were stable during storage at 8 °C of 56 days because the particle sizes measured by PCS were almost not changed. There was almost no leakage of resveratrol from liposomes PL 90G with cholesterol after diffusion test in dialysis tube for 28 days. All liposomes showed the sustained release during measuring time of 270 min. The maximum release amount of 16-20% was detected with liposomes from 2- and 3-chains-PEG-PL. The other liposomes gave max. release amount of resveratrol only of 10%. The release kinetic can be explained by Korsmeyer-Peppas equation. 

Keywords: Liposome, NTA, resveratrol, pegylation, cholesterol.

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360 Heat Transfer from Two Cam Shaped Cylinders in Tandem Arrangement

Authors: Arash Mir Abdolah Lavasani, Hamidreza Bayat

Abstract:

Heat transfer from two cam shape cylinder in tandem arrangement had been studied numerically. The distance between the centers of cylinders (L) is allowed to vary to change the longitudinal pitch ratio (L/Deq). The equivalent diameter of the cylinder (Deq) is 27.6 mm and longitudinal pitch ratio varies in range 2<L/Deq<6. The Reynolds number based on equivalent circular cylinder are within 50< Reeq <300. Results show that Nusselt number of second cylinder increases about 5 to 33 times when longitudinal pitch ratio increases from 2 to 6.

Keywords: Cam Shaped, tandem Cylinders, Numerical, Heat Transfer.

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359 Chitosan Nanoparticle as a Novel Delivery System for A/H1n1 Influenza Vaccine: Safe Property and Immunogenicity in Mice

Authors: Nguyen Anh Dzung, Nguyen Thi Ngoc Hà, Dang Thi Hong Van, Nguyen Thi Lan Phuong, Nguyen Thi Nhu Quynh, Dinh Minh Hiep, Le Van Hiep

Abstract:

The aims of this paper are to study the efficacy of chitosan nanoparticles in stimulating specific antibody against A/H1N1 influenza antigen in mice. Chitosan nanoparticles (CSN) were characterized by TEM. The results showed that the average size of CSN was from 80nm to 106nm. The efficacy of A/H1N1 influenza vaccine loaded on the surface of CSN showed that loading efficiency of A/H1N1 influenza antigen on CSN was from 93.75 to 100%. Safe property of the vaccine were tested. In 10 days post vaccination, group of CSN 30 kDa and 300 kDa loaded A/H1N1 influenza antigen were the rate of immune response on mice to be 100% (9/9) higher than Al(OH)3 and other adjuvant. 100% mice in the experiment of all groups had immune response in 20 days post vaccination. The results also showed that HI titer of the group using CSN 300 kDa as an adjuvant increased significantly up to 3971 HIU, over three-fold higher than the Al(OH)3 adjuvant, chitosan (CS), and one hundredfold than the A/H1N1 antigen only. Stability of the vaccine formulation was investigated.

Keywords: Chitosan nanoparticles, A/H1N1 influenza antigen, vaccine, immunogenicity, adjuvant, antibody titer

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358 Effect of a Multiple Stenosis on Blood Flow through a Tube

Authors: Vipin Kumar Verma, Praveen Saraswat

Abstract:

The development of double stenosis in an artery can have serious consequences and can disrupt the normal functioning of the circulatory system. It has been realized that various hydrodynamics effects (i.e. wall shear, pressure distribution etc.) play important role in the development of this disease. Generally in the literature, the cross-section of the artery is assumed to be uniform with a single stenosis. However, in real situation the multiple stenosis develops in series along the length of artery whose cross-section varies slowly. Therefore, the flow of blood is laminar through a small diameter artery with axisymmetric identical double stenosis in series.

Keywords: Wall shear, multiple stenosis, artery.

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357 Energy Absorption and Axial Tearing Behaviour of Metallic Tubes Using Angled Dies: Experimental and Numerical Simulation

Authors: V. K. Bheemineni, B. Käfer, H. Lammer, M. Kotnik, F. O. Riemelmoser

Abstract:

This paper concerns about the experimental and numerical investigations of energy absorption and axial tearing behaviour of aluminium 6060 circular thin walled tubes under static axial compression. The tubes are received in T66 heat treatment condition with fixed outer diameter of 42mm, thickness of 1.5mm and length of 120mm. The primary variables are the conical die angles (15°, 20° and 25°). Numerical simulations are carried on ANSYS/LS-DYNA software tool, for investigating the effect of friction between the tube and the die.

Keywords: Angled die, ANSYS/LS-DYNA, Axial tearing, Energy absorption.

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