Search results for: Risk daily dose intake

Authors: M. Allagoa, A. Al-Tabbaa

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The study explores the use of binders and additives, such as Portland cement, pulverized fuel ash, ground granulated blast furnace slag, and MgO, to reduce the concentration and leachability of pollutants in contaminated site soils. The research investigates their effectiveness and associated risks of binders, with a focus on Total Heavy Metals (THM) and Total Petroleum Hydrocarbon (TPH). The goal of this research is to evaluate the performance and effectiveness of binders and additives in remediating soil pollutants. The study aims to assess the suitability of the mixtures for ground improvement purposes, determine the optimal dosage, and investigate the associated risks. The research utilizes physical (unconfined compressive strength) and chemical tests (batch leachability test) to assess the efficacy of the binders and additives. A completely randomized design one-way ANOVA is used to determine the significance within mix binders of THM. The study also employs incremental lifetime cancer risk (ILCR) assessments and other indices to evaluate the associated risks. The study finds that Ground Granulated Blast Furnace Slag (GGBS): MgO is the most effective binder for remediation, particularly when using low dosages of MgO combined with higher dosages of GGBS binders on TPH. The results indicate that binders and additives can encapsulate and immobilize pollutants, thereby reducing their leachability and toxicity. The mean unconfined compressive strength of the soil ranges from 285.0-320.5 kPa, while THM levels with a combination of Ground granulated blast furnace slag and Magnesium oxide, Portland cement and Pulverised fuel ash were less than 10 µg/l. Portland cement was below 1 µg/l. The ILCR ranged from 6.77E-02 - 2.65E-01 and 5.444E-01 - 3.20 E+00, with the highest values observed under extreme conditions. The hazard index (HI), risk allowable daily dose intake (ADI), and risk chronic daily intake (CDI) were all less than 1 for the THM. The study identifies MgO as the best additive for use in soil remediation.

Keywords: Risk daily dose intake, risk chronic daily intake, incremental lifetime cancer risk, ILCR, novel binders, additives binders, hazard index.

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Authors: B. Salmasian, A. Rabiee, T. Yousefzadeh

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In this research, the risk assessment of radiation hazard for the Research Nuclear Reactor has been studied. In the current study, the MCNPx computational code has been used and coupled with a developed program using MATLAB software to evaluate Total Effective Dose Equivalent (TEDE) and cancer risk according to the BEIR equations for various human organs. In this study, the risk assessment of cancer has been calculated for ten years after exposure, in each of body organs of different ages and sexes. Also, the risk assessment of cancer has been calculated in each of body organs of different ages and sexes due to exposure after the retirement of the reactor staff. According to obtained results, a conservative whole-body dose rate, during a year, is 0.261 Sv and the probability the cancer risk for women is more than men and for children is more than adults. It has been shown that thyroid cancer was more possible than others.

Keywords: MCNPx code, BEIR equation, equivalent dose, risk analysis.

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Authors: Irisa Murniece, Daina Karklina, Ruta Galoburda

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From food consumption surveys has been found that potato consumption comparing to other European countries is one of the highest. Hence acrylamide (AA) intake coming from fried potatoes in population might be high as well. The aim of the research was to determine acrylamide content and estimate intake of acrylamide from roasted potatoes bred and cultivated in Latvia. Five common Latvian potato varieties were selected: Lenora, Brasla, Imanta, Zile, and Madara. A two-year research was conducted during two periods: just after harvesting and after six months of storage. Time and temperature (210 ± 5°C) was recorded during frying. AA was extracted from potatoes by solid phase extraction and AA content was determined by LC-MS/MS. estimated intake of acrylamide ranges from 0.012 to 0.496μgkg-1 BW per day.

Keywords: potato, roasting, variety, acrylamide, Latvia, risk assessment.

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Authors: N. Todorovic, I. Bikit, J. Nikolov, S. Forkapic, D. Mrdja, S. Todorovic

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Interventional cardiologists are at greater risk from radiation exposure as a result of the procedures they undertake than most other medical specialists. A study was performed to evaluate operator dose during interventional cardiology procedures and to establish methods of operator dose reduction with a radiation protective device. Different procedure technique and use of protective tools can explain big difference in the annual equivalent dose received by the professionals. Strategies to prevent and monitor radiation exposure, advanced protective shielding and effective radiation monitoring methods should be applied.

Keywords: absorbed dose rate measurements, annualequivalent dose, protective device.

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Authors: Fridhi Hadia, Soua Wadhah, Hidouri Ammar, Omri Ahmed

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In this paper, the effect of the intake temperature (IT) and intake pressure (IP) on ignition timing and pollutants emission of Homogeneous Charge Compression Ignition (HCCI) engine is investigated. Numerical computations are performed using the CHEMKIN computer code. The numerical temperature obtained using different boundary conditions is compared to published data and a good agreement is assigned. Results show that the HCCI combustion engine is significantly improved by increasing the IT. With a value of IT lower than 390 K, combustion cannot occur. However, with an IT greater than 420 K, the cylinder pressure decreases. An optimum crank rotation angle is achieved by using IT of 420 K. So, we can conclude that the variation of the IT and IP influence notably the emission concentration.

Keywords: HCCI engine, CEMKIN, intake temperature, intake pressure.

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Authors: H. H. Huynh, J. Meunier, J.Sequeira, M.Daniel

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In this paper, the detection and tracking of face, mouth, hands and medication bottles in the context of medication intake monitoring with a camera is presented. This is aimed at recognizing medication intake for elderly in their home setting to avoid an inappropriate use. Background subtraction is used to isolate moving objects, and then, skin and bottle segmentations are done in the RGB normalized color space. We use a minimum displacement distance criterion to track skin color regions and the R/G ratio to detect the mouth. The color-labeled medication bottles are simply tracked based on the color space distance to their mean color vector. For the recognition of medication intake, we propose a three-level hierarchal approach, which uses activity-patterns to recognize the normal medication intake activity. The proposed method was tested with three persons, with different medication intake scenarios, and gave an overall precision of over 98%.

Keywords: Activity recognition, background subtraction, tracking, medication intake, video surveillance

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Authors: L. Labéjof, I. Mororó, P. Galle, G. Barbosa, M.I. Severo, A.H. de Oliveira

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Ultrastructure of duodenum mucosa of irradiated rat was studied versus dose rate of irradiation following exposure to gamma rays from 60-Cobalt source. The animals were whole body irradiated at two dose rates (1 Gy.mn-1 and 1 Gy.h-1) and three total doses (1, 2 or 4 Gy) for each dose rate. 24 or 48 h after irradiation, their small intestine was removed and samples of duodenum were processed for observations under a transmission electron microscopy. Samples of duodenum mucosa of control rats were processed in the same way. For the lower dose rate of 1 Gy.h-1, main lesions characteristic of apoptosis were detected within irradiated enterocytes at a total dose of 2 Gy and 24 h after exposure. Necrosis was noted in the samples, 48 h after exposition. For the higher dose rate of 1 Gy.mn-1, fewer changes were detected at all total doses 24 or 48 h irradiation. Thus, it was shown that the appearance of radiationinduced alterations varies not only with increasing total dose and post-irradiation time but especially with decreasing dose rate.

Keywords: Dose rate, Radiation Inury, Apoptosis, SmallBowel

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Authors: J. Bertrandt, A. Kłos, R. Waszkowski, T. Nowicki, R. Pytlak, E. Stęzycka, A. Gazdzinska

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 The aim of the work was estimation of copper intake with the daily food rations used for alimentation of students of military high schools and soldiers doing compulsory military service in the Polish Army. An average planned copper content in daily food rations used for alimentation of students and soldiers amounted to 2.49±0.35 mg, and 2.44±0.25 mg respectively. The copper content in the daily food ration given for consumption to students amounted from 1.81±0.14 mg to 2.58±0.44 mg while daily food rations served to soldiers delivered from 2.06±0.45 mg to 2.13±0.33 mg. The copper content in the rations planned for students and soldiers alimentation was within the limits of the norms obligatory in Poland. Daily food rations given for consumption, except rations served for students, were within the limits of the recommended norms, but food rations really eaten by examined men didn’t cover the requirements for copper.

Keywords: Copper, daily food ration, military service.

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Authors: Ademuyiwa, M. O., Sanni, S. A.

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The importance of maternal nutritional practices during pregnancy cannot be overemphasized. This paper assessed the consumption pattern and dietary practices of 50 pregnant women selected using purposive sampling technique from three health care centres (Primary Health Care Centre, Obantoko; Primary Health Care Centre Alabata; and the General Hospital, Odeda) in Odeda Local Government Area of Ogun State, Nigeria. Structured questionnaire was used to elicit information on socioeconomic status, consumption pattern and dietary practices. Data were analyzed using the Statistical Package for Social Sciences (SPSS, 17). The results indicated that about 58% of the pregnant women were below the age of 30 while 42% were ages 28-40 years. Only 16% had tertiary education while (38%) had secondary education, 52% earn income through petty trading. On food intake, 52% got their energy source from rice on a daily basis, followed by pap (38%) and eko (34%). For protein intake, 36% consumed bean cake on a daily basis while 66% consumed moinmoin 2-3 times a week. Orange (48%) and Green Leafy vegetable (40%) accounted for the mostly consumed fruit and vegetable on daily basis. In terms of animal origin, fish (76%), meat (58%) and eggs (30%) were consumed daily, while chicken and snail were consumed occasionally by 54% and 42%, respectively. Forty-six percent (46%) of the pregnant women eat more than three times daily; while 60% of the women eat outside their homes with 42% respondents eat out lunch and only two percent least eaten out dinner. It is important to increase in awareness campaign to sensitize the pregnant women on the importance of good nutrition especially fruits, vegetables and dairy products. 

Keywords: Consumption Pattern, Dietary Practices, Pregnant, Women, Nigeria.

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Authors: R. Mehra

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The measurements of 226Ra, 232Th and 40K using gamma spectrometry and radon concentration and exhalation rates measurements using solid state nuclear track (LR-115, Type-II plastic) detectors are used to asses a first order exposure risk for the persons residing in Fatehbad and Hissar districts of Western Haryana, India. The concentration of Radium, Thorium and Potassium in the soil samples varies from 13.37 Bq m-3 to 24.67 Bq m-3, 34.67 Bq m-3 to 67.34 Bq m-3 and 298.78 Bq m-3 to 405.67 Bq m-3 respectively with average values of 18.78, 47.35 and 361.57 Bq m-3 respectively. The radium equivalent activity (Raeq) calculated for the same soil samples varies from 92.72 Bq m-3 to 140.6 Bq m-3 with an average value of 111.80 Bq m-3. The values of absorbed dose and annual effective dose (indoors and outdoors) are found to vary from 44.18 nGy h-1 to 65.23 nGy h-1, 0.22 mSv y-1 to 0.32 mSv y-1 and 0.05 mSv y-1 to 0.08 mSv y-1 respectively. The radon concentration and exhalation rates have also been reported. The radium equivalent activities in all the soil samples were found to be lower than the limit (370 Bq kg-1) set in the Organization for Economic Cooperation and Development (OECD) report and the value of Hex in all the samples is less than unity.

Keywords: Gamma ray spectrometry, dose, radon, exhalationrate.

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Authors: Inas E. Darwish, Alia M. Arab, Tarek A. Azeim, Teshreen M. Zeitoun, Wafaa A. Hewedy, Moemen A. Heiba, Iman S. Emara

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Inflammatory bowel disease (IBD) is a chronic relapsing-remitting condition that afflicts millions of people throughout the world and impairs their daily functions and quality of life. Treatment of IBD depends largely on 5-aminosalicylic acid (5- ASA) and corticosteroids. The present study aimed to clarify the effects of 5-aminosalicylic acid, budesonide and currcumin on 90 male albino rats against trinitrobenzene sulfonic acid (TNB) induced colitis. TNB was injected intrarectally to 50 rats. The other 40 rats served as control groups. Both 5-ASA (in a dose of 120 mg/kg) and budesonide (in a dose of 0.1 mg/kg) were administered daily for one week whereas currcumin was injected intraperitonially (in a dose of 30 mg/kg daily) for 14 days after injection of either TNB in the colitis rats (group B) or saline in control groups (group A). The study included estimation of macroscopic score index, histological examination of H&E stained sections of the colonic tissue, biochemical estimation of myeloperoxidase (MPO), nitric oxide (NO), and caspase-3 levels, in addition to studying the effect of tested drugs on colonic motility. It was found that budesonide and curcumin improved mucosal healing, reduced both NO production and caspase- 3 level. They had the best impact on the disturbed colonic motility in TNBS-model of colitis.

Keywords: Colitis, curcumin, nitric oxide.

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Authors: K. Reza-Yazdi, M. Fallah, M. Khodaparast, F. Kateb, M. Hosseini-Ghaffari

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The objective of this study was to determine effect of dietary essential oil (EO) compounds, which contained cinnamaldehyde, eugenol, peppermint, coriander, cumin, lemongrass, and an organic carrier on feed intake, milk composition, and rumen fermentation of dairy cows during heat exposure. Thirty-two Holstein cows (days in milk= 60 ± 5) were assigned to one of two treatment groups: a Control and EO fed. The experiment lasted 28 days. Dry matter intake (DMI) was measured daily while and milk production was measured weekly. Our result showed that DMI and milk yield was decreased (P < 0.01) in control cows relative to EO cows. Furthermore, supplementation with EO was associated with a decrease in the molar proportion of propionate (P < 0.05) and increase (P < 0.05) in acetate to propionate ratio. In conclusion, EO supplementations in diets can be useful nutritional modification to alleviate for the decrease DMI and milk production during heat exposure in lactating dairy cows.

Keywords: Dairy cow, feed additive, plant extract.

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Authors: N. Moradian, E. Timofeev, R. Tahir

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In this work, startability of the Busemann intake family with weak/strong conical shock, as most efficient intakes, via overboard mass spillage method is theoretically analyzed. Masterix and Candifix codes are used to numerically simulate few models of this type of intake and verify the theoretical results. Portions of the intake corresponding to various flow capture angles are considered to have mass spillage in the starting process of this intake. This approach allows for overboard mass spillage via a V-shaped slot with the tip of V coinciding with the focal point of the Busemann flow. The theoretical results, achieved using two different theories, of self-started Busemann takes with weak/strong conical shock show that significant improve in intake startability using overboard spillage technique. The starting phenomena of Busemann intakes with weak conical shock and seven different capture angles are numerically simulated at freestream Mach number of 3 to find the minimum area ratios of self-started intakes. The numerical results confirm the theoretical ones achieved by authors.

Keywords: Busemann intake, conical shock, overboard spillage, startability.

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Authors: V. A. Vieira, M. P. Sforcini, V. Endo, G. C. Magioni, M. D. S. Oliveira

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The main goal of this paper was evaluate the effect of diets containing different levels of probiotic on performance and milk composition of lactating cows. Eight Holstein cows were distributed in two 4x4 Latin square. The diets were based on corn silage, concentrate and the treatment (0, 3, 6 or 9 grams of probiotic/animal/day). It was evaluated the dry matter intake of nutrients, milk yield and composition. The use of probiotics did not affect the nutrient intake (p>0.05) neither the daily milk production or corrected to 4% fat (p>0.05). However, it was observed that there was a significant fall in milk composition with higher levels of probiotics supplementation. These results emphasize the need of further studies with different experimental designs or improve the number of Latin square with longer periods of adaptation.

Keywords: Dairy cow, milk composition, probiotics.

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Authors: Marjan Mahdavi-Roshan, Arsalan Salari, Mahboobeh Gholipour, Moona Naghshbandi

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Background and objectives: Before any nutritional intervention, it is necessary to have the prospect of eating habits of people with cardiovascular risk factors. In this study, we assessed the adherence of healthy diet based on Mediterranean dietary pattern and related factors in adults in the north of Iran. Methods: This study was conducted on 550 men and women with cardiovascular risk factors that referred to Heshmat hospital in Rasht, northern Iran. Information was collected by interview and reading medical history and measuring anthropometric indexes. The Mediterranean Diet Adherence Screener was used for assessing dietary adherence, this screener was modified according to religious beliefs and culture of Iran. Results: The mean age of participants was 58±0.38 years. The mean of body mass index was 27±0.01 kg/m², and the mean of waist circumference was 98±0.2 cm. The mean of dietary adherence was 5.76±0.07. 45% of participants had low adherence, and just 4% had suitable adherence. The mean of dietary adherence in men was significantly higher than women (p=0. 07). Participants in rural area and high educational participants insignificantly had an unsuitable dietary Adherence. There was no significant association between some cardiovascular disease risk factors and dietary adherence. Conclusion: Education to different group about dietary intake correction and using a Mediterranean dietary pattern that is similar to dietary intake in the north of Iran, for controlling cardiovascular disease is necessary.

Keywords: Dietary adherence, Mediterranean dietary pattern, cardiovascular disease, north of Iran.

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Authors: Dewi Fatmaningrum, Ade Wiradnyani

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Optimal feeding, including optimal micronutrient intake, becomes one of the ways to overcome the long-term consequences of undernutrition. Macronutrient and micronutrient intake were important to a rapid growth and development of young children. The study objective was to assess macro and micronutrient intake and its adequacy in children aged 12-23 months. This survey was a cross-sectional study, involving 83 caregivers with children aged 12-23 months old in Senen Sub-district, Central Jakarta selected through simple random sampling. Data on nutrient intake was obtained through interview using single 24-hour recall. Repeated 24- hour recall to sub-sample was done to estimate the proportion of nutrient inadequacy. The highest prevalence of nutrient inadequacy was iron (52.4%), followed by vitamin C (30.9%) and zinc (28.8%). Almost 12% children had inadequate energy intake. More than half of children (62.6%) were anemic (25.3% were severely anemic). Micronutrient inadequacy, especially iron, was more problematic than macronutrient inadequacy in the study area.

Keywords: Micronutrient, macronutrient, children under five, urban setting.

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Authors: Jaya Mahar Maligan, Teti Estiasih, Joni Kusnadi

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Structured phospholipids from commercial soybean lecithin with oil enriched omega-3 fatty acid form by product of tuna canning is alternative procedure to provides the stability of omega-3 fatty acid structure and increase these bioactive function in metabolism. Best treatment condition was obtain in 18 hours acidolysis reaction with 30% enzyme concentration, which EPADHA incorporation level was 127,47 mg/g and incorporation percentage of EPA-DHA was 51,04% at phospholipids structure. This structured phospolipids could reduce atherosclerosis risk in male Sprague dawley rat. Provision of structured phospholipids has significant effect (α = 0.05) on changes in lipid profile, intima-media thickness of aorta rats (male Sprague dawley) fed atherogenic diet. Structured phospholipids intake can lower total cholesterol 78.36 mg/dL, total triglycerides 94,57 mg/dL, LDL levels 87.08 mg/dL and increased HDL level as much as 12,64 mg/dL in 10 weeks cares. Structured phospholipids intake also can prevent the thickening of the intima-media layer of the aorta.

Keywords: Structured phospholipids, commercial soybean lecithin, omega-3 fatty acid, atherosclerosis risk.

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Authors: Ananya Das, Arun Kumar, Gazala Habib, Vivekanandan Perumal

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Regulatory bodies has proposed limits on Particulate Matter (PM) concentration in air; however, it does not explicitly indicate the incorporation of effects of toxicities of constituents of PM in developing regulatory limits. This study aimed to provide a structured approach to incorporate toxic effects of components in developing regulatory limits on PM. A four-step human health risk assessment framework consists of - (1) hazard identification (parameters: PM and its constituents and their associated toxic effects on health), (2) exposure assessment (parameters: concentrations of PM and constituents, information on size and shape of PM; fate and transport of PM and constituents in respiratory system), (3) dose-response assessment (parameters: reference dose or target toxicity dose of PM and its constituents), and (4) risk estimation (metric: hazard quotient and/or lifetime incremental risk of cancer as applicable). Then parameters required at every step were obtained from literature. Using this information, an attempt has been made to determine limits on PM using component-specific information. An example calculation was conducted for exposures of PM_2.5 and its metal constituents from Indian ambient environment to determine limit on PM values. Identified data gaps were: (1) concentrations of PM and its constituents and their relationship with sampling regions, (2) relationship of toxicity of PM with its components.

Keywords: Air, component-specific toxicity, human health risks, particulate matter.

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Authors: Florence Uchendu, Tola Atinmo

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Nigerian bread is baked with vitamin A fortified wheat flour. Study aimed at determining its contribution to preschoolers- vitamin A nutriture. A cross-sectional/experimental study was carried out in four poor-urban Local Government Areas (LGAs) of Metropolitan Lagos, Nigeria. A pretested food frequency questionnaire was administered to randomly selected mothers of 1600 preschoolers (24-59 months). Retinyl Palmitate content of fourteen bread samples randomly collected from bakeries in all LGAs was analyzed at 0 and 5 days at 25oC using High Performance Liquid Chromatography. Data analysis was done at p<.05. Mean total intake of vitamin A from bread was 220.40μgRAE (733.94±775.68i.u). Bread contributed 6.5–178.4% of preschoolers RDA (1333i.u/400μgRAE). Mean contribution to vitamin A intake was 55.06±58.18%. Strong statistical significant relationship existed between total vitamin A intake and % RDA which was directly proportional (p<.01). Result indicates that bread made an important contribution towards vitamin A intake in poor-urban Lagosian preschoolers.

Keywords: Bread, dietary intake, Lagos metropolis, preschoolers

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Authors: Ali Mirmohammadi, Arash Taheri, Meysam Mohammadi-Amin

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One of the major parts of a jet engine is air intake, which provides proper and required amount of air for the engine to operate. There are several aerodynamic parameters which should be considered in design, such as distortion, pressure recovery, etc. In this research, the effects of lip ice accretion on pitot intake performance are investigated. For ice accretion phenomenon, two supervised multilayer neural networks (ANN) are designed, one for ice shape prediction and another one for ice roughness estimation based on experimental data. The Fourier coefficients of transformed ice shape and parameters include velocity, liquid water content (LWC), median volumetric diameter (MVD), spray time and temperature are used in neural network training. Then, the subsonic intake flow field is simulated numerically using 2D Navier-Stokes equations and Finite Volume approach with Hybrid mesh includes structured and unstructured meshes. The results are obtained in different angles of attack and the variations of intake aerodynamic parameters due to icing phenomenon are discussed. The results show noticeable effects of ice accretion phenomenon on intake behavior.

Keywords: Artificial Neural Network, Ice Accretion, IntakeAerodynamics, Design Parameters, Finite Volume Method.

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Authors: S. Bureenok, C. Yuangklang, K. Vasupen

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The effect of cassava root ensiled with cassava top or legumes on voluntary feed intake and milk production were determined in 12 dairy cows using a 4×3 change-over design. Experimental period were 30 days long and consisted of 14 days of adaptation. Silage was prepared from cassava root mixed with cassava top or legumes at ratio 60:40. Cows were allotted at random to receive ad libitum one of four rations: T1) control, T2) cassava root +cassava top-silages, T3) cassava root +hamata - silages and T4) cassava root +Thapra stylo-silages. The dry matter intake (BW0.75) was higher (P< 0.05) in cow fed with silages diets compared with T1. However, the intake of T2 was higher among treatments. Milk production was lowest in cow fed with T1. Among silages based diets, milk production was not significantly different but 4%FCM was higher in cow fed T2. Milk compositions were not affected by feeding diets. It is concluded that feeding cassava root ensiled with its leaves as a supplement increased dry matter intake and significantly improved 4%FCM. The combination of cassava root and legume silages did not improve the feed intake but did increase the milk production.

Keywords: Cassava, dairy cow, hamata, Thapra stylo, silage.

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Authors: Sadegh Masoudi, Ali Asghar Yousefi, Somayeh Nourollahi, Fatemeh Noughani

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Two different testicular tissues have to be distinguished in regard to radiation damage: first the seminiferous tubules, corresponding to the sites of spermatogenesis, which are extremely radiosensitive. Second the testosterone secreting Leydig cells, which are considered to be less radiosensitive. This study aims to estimate testicular dose and the associated risks for infertility and hereditary effects from Abdominal and pelvic irradiation. Radiotherapy was simulated on a humanoid phantom using a 15 MV photon beam. Testicular dose was measured for various field sizes and tissue thicknesses along beam axis using an ionization chamber and TLD. For transmission Factor Also common method of measuring the absorbed dose distribution and electron contamination in the build-up region of high-energy beams for radiation therapy is by means of parallel-plate Ionisation chambers. Gonadal dose was reduced by placing lead cups around the testes supplemented by a field edge block. For a tumor dose of 100 cGy, testicular dose was 2.96-8.12 cGy depending upon the field size and the distance from the inferior field edge. The treatment at parameters, the presence of gonad shield and the somatometric characteristics determine whether testicular dose can exceed 1 Gy which allows a complete recovery of spermatogenesis.

Keywords: Absorbed Dose, Abdominal and pelvic, gonads men, Radiotherapy.

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Authors: Mohamed A. Hammad, Dzul Azri Mohamed Noor, Syed Azhar Syed Sulaiman, Ahmed A. Khamis, Abeer Kharshid, Nor Azizah Aziz

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The effect of statins dose intensity (SDI) on glycemic control in patients with existing diabetes is unclear. Also, there are many contradictory findings were reported in the literature; thus, it is limiting the possibility to draw conclusions. This project was designed to compare the effect of SDI on glycated hemoglobin (HbA1c%) control in outpatients with Type 2 diabetes in the endocrine clinic at Hospital Pulau Pinang, Malaysia, between July 2015 and August 2016. A prospective cohort study was conducted, where records of 345 patients with Type 2 diabetes (Moderate-SDI group 289 patients and high-SDI cohort 56 patients) were reviewed to identify demographics and laboratory tests. The target of glycemic control (HbA1c < 7% for patient < 65 years, and < 8% for patient ≥ 65 years) was estimated, and the results were presented as descriptive statistics. From 289 moderate-SDI cohorts with a mean age of 57.3 ± 12.4 years, only 86 (29.8%) cases were shown to have controlled glycemia, while there were 203 (70.2%) cases with uncontrolled glycemia with confidence interval (CI) of 95% (6.2–10.8). On the other hand, the high-SDI group of 56 patients with Type 2 diabetes with a mean age 57.7±12.4 years is distributed among 11 (19.6%) patients with controlled diabetes, and 45 (80.4%) of them had uncontrolled glycemia, CI: 95% (7.1–11.9). The study has demonstrated that the relative risk (RR) of uncontrolled glycemia in patients with Type 2 diabetes that used high-SDI is 1.15, and the excessive relative risk (ERR) is 15%. The absolute risk (AR) is 10.2%, and the number needed to harm (NNH) is 10. Outpatients with Type 2 diabetes who use high-SDI of statin have a higher risk of uncontrolled glycemia than outpatients who had been treated with a moderate-SDI.

Keywords: Cohort study, diabetes control, dose intensity, HbA1c, Malaysia, statin, Type 2 diabetes mellitus, uncontrolled glycemia.

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Authors: L. Lindsay, S. A. Coleman, D. Kerr, B. J. Taylor, A. Moorhead

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Cognitive decline and frailty is apparent in older adults leading to an increased likelihood of the risk of falling. Currently health care professionals have to make professional decisions regarding such risks, and hence make difficult decisions regarding the future welfare of the ageing population. This study uses health data from The Irish Longitudinal Study on Ageing (TILDA), focusing on adults over the age of 50 years, in order to analyse health risk factors and predict the likelihood of falls. This prediction is based on the use of machine learning algorithms whereby health risk factors are used as inputs to predict the likelihood of falling. Initial results show that health risk factors such as long-term health issues contribute to the number of falls. The identification of such health risk factors has the potential to inform health and social care professionals, older people and their family members in order to mitigate daily living risks.

Keywords: Classification, falls, health risk factors, machine learning, older adults.

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Authors: Seyed Ahmad Hosseini, Makan Cheraghpour, Saeed Shirali, Roya Rafie, Matin Ghanavati, Arezoo Amjadi, Meysam Alipour

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Background: There is a mutual relationship between sleep duration and obesity. We studied the relationship between sleep duration with obesity and dietary Intake. Methods: This cross-sectional study was conducted on 444 male students in Ahvaz Jundishapur University of Medical Science. Dietary intake was analyzed by food frequency questionnaire (FFQ). Anthropometric indices were analyzed. Participants were being asked about their sleep duration and they were categorized into three groups according to their responses (less than six hours, between six and eight hours, and more than eight hours). Results: Macronutrient, micronutrient, and antioxidant intake did not show significant difference between three groups. Moreover, we did not observe any significant difference between anthropometric indices (weight, body mass index, waist circumference, and percentage body fat). Conclusions: Our study results show no significant relationship between sleep duration, nutrition pattern, and obesity. Further study is recommended.

Keywords: Sleep duration, obesity, dietary intake, cross-sectional.

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Authors: T. S. Shashikumar

Abstract:

Radon is a radioactive gas emitted from radium, a daughter product of uranium that occurs naturally in rocks and soil. Radon, together with its decay products, emits alpha particles that can damage lung tissue. The activity concentration of ²²²Ra has been analyzed in water samples collected from borewells and rivers in and around Hassan city, Karnataka State, India. The measurements were performed by Emanometry technique. The concentration of ²²²Rn in borewell waters varies from 18.49±1.89 to 397.26±12.3 Bql^-1 with geometric mean 120.48±12.87 Bql^-1 and in river waters it varies from 92.63±9.31 to 93.98±9.51 Bql^-1 with geometric mean of 93.16±9.33 Bql^-1. In the present study, the radon concentrations are higher in Adarshanagar and Viveka Nagar which are found to be 397.26±12.3 Bql^-1 and 325.78±32.56 Bql^-1. Most of the analysed samples show a ²²²Rn concentration more than 100 Bql^-1 and this can be attributed to the geology of the area where the ground waters are located, which is predominantly of granitic characteristic. The average inhalation dose and ingestion dose in the borewell water are found to be 0.405 and 0.033 µSvy^-1; and in river water it is found to be 0.234 and 0.019 µSvy^-1, respectively. The average total effective dose rate in borewell waters and river waters are found to be 0.433 and 0.253 µSvy^-1, which does not cause any health risk to the population of Hassan region.

Keywords: Borewell, effective dose, emanometry, 222Rn.

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Authors: M.R. Mansoujian, N. Hedayat, M. Mashal, H, Kiamanesh

Abstract:

Analytical investigation of the sedimentation processes in the river engineering and hydraulic structures is of vital importance as this can affect water supply for the cultivating lands in the command area. The reason being that gradual sediment formation behind the reservoir can reduce the nominal capacity of these dams. The aim of the present paper is to analytically investigate sedimentation process along the river course and behind the storage reservoirs in general and the Eastern Intake of the Dez Diversion weir in particular using the SHARC software. Results of the model indicated the water level at 115.97m whereas the real time measurement from the river cross section was 115.98 m which suggests a significantly close relation between them. The average transported sediment load in the river was measured at 0.25mm , from which it can be concluded that nearly 100% of the suspended loads in river are moving which suggests no sediment settling but indicates that almost all sediment loads enters into the intake. It was further showed the average sediment diameter entering the intake to be 0.293 mm which in turn suggests that about 85% of suspended sediments in the river entre the intake. Comparison of the results from the SHARC model with those obtained form the SSIIM software suggests quite similar outputs but distinguishing the SHARC model as more appropriate for the analysis of simpler problems than other model.

Keywords: SHARC, Eastern Intake, Dez Diversion Weir.

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Authors: Aifa Afirah Rozlan, Mohamad Suhaimi Jaafar, Azhar Abdul Rahman

Abstract:

Raman spectroscopy are used to characterize the chemical changes in normoxic polyhydroxyethylacrylate gel dosimeter (PHEA) induced by radiation. Irradiations in the low dose region are performed and the polymerizations of PHEA gels are monitored by the observing the changes of Raman shift intensity of the carbon covalent bond of PHEA originated from both monomer and the cross-linker. The variation in peak intensities with absorbed dose was observed. As the dose increase, the peak intensities of covalent bond of carbon in the polymer gels decrease. This point out that the amount of absorbed dose affect the polymerization of polymer gels. As the absorbed dose increase, the polymerizations also increase. Results verify that PHEA gel dosimeters are sensitive even in lower dose region.

Keywords: normoxic polymer gel, ascorbic acid, Ramanspectroscopy, radiation dosimetry.

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Authors: M. Ebrahimi Shohani, S. M. Taheri, S. M. Golgoun

Abstract:

Environmental radiation dosimeter is a kind of detector that measures the dose of the radiation area. Dosimeter registers the radiation and converts it to the dose according to the calibration parameters. The limit of a dose is different at each radiation area and this limit should be notified and reported to the user and health physics department. The stochastic nature of radiation is the reason for the fluctuation of any gamma detector dosimetry. In this research we investigated Geiger-Muller type of dosimeter and tried to improve the dose measurement. Geiger-Muller dosimeter is a counter that converts registered radiation to the dose. Therefore, for better data analysis, it is necessary to apply an algorithm to smooth statistical variations of registered radiation. We proposed a method to smooth these fluctuations much more and also proposed a dynamic way to trace rapid changes of radiations. Results show that our method is fast and reliable method in comparison the traditional method.

Keywords: Geiger-Muller, radiation detection, smoothing algorithms, dosimeter, dose calculation.

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Authors: J. R. Wang, H. C. Chen, C. Shih, S. W. Chen, J. H. Yang, Y. Chiang

Abstract:

In this study, we focus on the establishment of the analysis model for Maanshan PWR nuclear power plant (NPP) by using RADTRAD and SNAP codes with the FSAR, manuals, and other data. In order to evaluate the cumulative dose at the Exclusion Area Boundary (EAB) and Low Population Zone (LPZ) outer boundary, Maanshan NPP RADTRAD/SNAP model was used to perform the analysis of the DBA LOCA case. The analysis results of RADTRAD were similar to FSAR data. These analysis results were lower than the failure criteria of 10 CFR 100.11 (a total radiation dose to the whole body, 250 mSv; a total radiation dose to the thyroid from iodine exposure, 3000 mSv).

Keywords: RADionuclide, transport, removal, and dose estimation, RADTRAD, symbolic nuclear analysis package, SNAP, dose, PWR.

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