@article{(Open Science Index):https://publications.waset.org/pdf/1324,
	  title     = {Effect of Dose Rate of Irradiation on Ultrastructure of Duodenal Mucosa},
	  author    = {L. Labéjof and  I. Mororó and  P. Galle and  G. Barbosa and  M.I. Severo and  A.H. de Oliveira},
	  country	= {},
	  institution	= {},
	  abstract     = {Ultrastructure of duodenum mucosa of irradiated rat
was studied versus dose rate of irradiation following exposure to
gamma rays from 60-Cobalt source. The animals were whole body
irradiated at two dose rates (1 Gy.mn-1 and 1 Gy.h-1) and three total
doses (1, 2 or 4 Gy) for each dose rate. 24 or 48 h after irradiation,
their small intestine was removed and samples of duodenum were
processed for observations under a transmission electron microscopy.
Samples of duodenum mucosa of control rats were processed in the
same way. For the lower dose rate of 1 Gy.h-1, main lesions
characteristic of apoptosis were detected within irradiated enterocytes
at a total dose of 2 Gy and 24 h after exposure. Necrosis was noted in
the samples, 48 h after exposition. For the higher dose rate of 1
Gy.mn-1, fewer changes were detected at all total doses 24 or 48 h
irradiation. Thus, it was shown that the appearance of radiationinduced
alterations varies not only with increasing total dose and
post-irradiation time but especially with decreasing dose rate.},
	    journal   = {International Journal of Biotechnology and Bioengineering},
	  volume    = {4},
	  number    = {8},
	  year      = {2010},
	  pages     = {492 - 499},
	  ee        = {https://publications.waset.org/pdf/1324},
	  url   	= {https://publications.waset.org/vol/44},
	  bibsource = {https://publications.waset.org/},
	  issn  	= {eISSN: 1307-6892},
	  publisher = {World Academy of Science, Engineering and Technology},
	  index 	= {Open Science Index 44, 2010},