Search results for: Genetic data
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 7935

Search results for: Genetic data

7725 Parameters Identification of Mathematical Model of the Fission Yeast Cell Cycle Control Using Evolutionary Strategy

Authors: A. Ghaffari, A. S. Mostafavi

Abstract:

Complex assemblies of interacting proteins carry out most of the interesting jobs in a cell, such as metabolism, DNA synthesis, mitosis and cell division. These physiological properties play out as a subtle molecular dance, choreographed by underlying regulatory networks that control the activities of cyclin-dependent kinases (CDK). The network can be modeled by a set of nonlinear differential equations and its behavior predicted by numerical simulation. In this paper, an innovative approach has been proposed that uses genetic algorithms to mine a set of behavior data output by a biological system in order to determine the kinetic parameters of the system. In our approach, the machine learning method is integrated with the framework of existent biological information in a wiring diagram so that its findings are expressed in a form of system dynamic behavior. By numerical simulations it has been illustrated that the model is consistent with experiments and successfully shown that such application of genetic algorithms will highly improve the performance of mathematical model of the cell division cycle to simulate such a complicated bio-system.

Keywords: Cell cycle, Cyclin-dependent kinase, Fission yeast, Genetic algorithms, Mathematical modeling, Wiring diagram

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7724 The Knowledge Representation of the Genetic Regulatory Networks Based on Ontology

Authors: Ines Hamdi, Mohamed Ben Ahmed

Abstract:

The understanding of the system level of biological behavior and phenomenon variously needs some elements such as gene sequence, protein structure, gene functions and metabolic pathways. Challenging problems are representing, learning and reasoning about these biochemical reactions, gene and protein structure, genotype and relation between the phenotype, and expression system on those interactions. The goal of our work is to understand the behaviors of the interactions networks and to model their evolution in time and in space. We propose in this study an ontological meta-model for the knowledge representation of the genetic regulatory networks. Ontology in artificial intelligence means the fundamental categories and relations that provide a framework for knowledge models. Domain ontology's are now commonly used to enable heterogeneous information resources, such as knowledge-based systems, to communicate with each other. The interest of our model is to represent the spatial, temporal and spatio-temporal knowledge. We validated our propositions in the genetic regulatory network of the Aarbidosis thaliana flower

Keywords: Ontological model, spatio-temporal modeling, Genetic Regulatory Networks (GRNs), knowledge representation.

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7723 Synchrony between Genetic Repressilators in Sister Cells in Different Temperatures

Authors: Jerome G. Chandraseelan, Samuel M. D. Oliveira, Antti Häkkinen, Sofia Startceva, Andre S. Ribeiro

Abstract:

We used live E. coli containing synthetic genetic oscillators to study how the degree of synchrony between the genetic circuits of sister cells changes with temperature. We found that both the mean and the variability of the degree of synchrony between the fluorescence signals from sister cells are affected by temperature. Also, while most pairs of sister cells were found to be highly synchronous in each condition, the number of asynchronous pairs increased with increasing temperature, which was found to be due to disruptions in the oscillations. Finally we provide evidence that these disruptions tend to affect multiple generations as opposed to individual cells. These findings provide insight in how to design more robust synthetic circuits and in how cell division can affect their dynamics.

Keywords: Repressilator, robustness, synchrony, synthetic biology.

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7722 Optimization of Bit Error Rate and Power of Ad-hoc Networks Using Genetic Algorithm

Authors: Anjana Choudhary

Abstract:

The ad hoc networks are the future of wireless technology as everyone wants fast and accurate error free information so keeping this in mind Bit Error Rate (BER) and power is optimized in this research paper by using the Genetic Algorithm (GA). The digital modulation techniques used for this paper are Binary Phase Shift Keying (BPSK), M-ary Phase Shift Keying (M-ary PSK), and Quadrature Amplitude Modulation (QAM). This work is implemented on Wireless Ad Hoc Networks (WLAN). Then it is analyze which modulation technique is performing well to optimize the BER and power of WLAN.

Keywords: Bit Error Rate, Genetic Algorithm, Power, Phase Shift Keying, Quadrature Amplitude Modulation, Signal to Noise Ratio, Wireless Ad Hoc Networks.

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7721 Solving Weighted Number of Operation Plus Processing Time Due-Date Assignment, Weighted Scheduling and Process Planning Integration Problem Using Genetic and Simulated Annealing Search Methods

Authors: Halil Ibrahim Demir, Caner Erden, Mumtaz Ipek, Ozer Uygun

Abstract:

Traditionally, the three important manufacturing functions, which are process planning, scheduling and due-date assignment, are performed separately and sequentially. For couple of decades, hundreds of studies are done on integrated process planning and scheduling problems and numerous researches are performed on scheduling with due date assignment problem, but unfortunately the integration of these three important functions are not adequately addressed. Here, the integration of these three important functions is studied by using genetic, random-genetic hybrid, simulated annealing, random-simulated annealing hybrid and random search techniques. As well, the importance of the integration of these three functions and the power of meta-heuristics and of hybrid heuristics are studied.

Keywords: Process planning, weighted scheduling, weighted due-date assignment, genetic search, simulated annealing, hybrid meta-heuristics.

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7720 Digital filters for Hot-Mix Asphalt Complex Modulus Test Data Using Genetic Algorithm Strategies

Authors: Madhav V. Chitturi, Anshu Manik, Kasthurirangan Gopalakrishnan

Abstract:

The dynamic or complex modulus test is considered to be a mechanistically based laboratory test to reliably characterize the strength and load-resistance of Hot-Mix Asphalt (HMA) mixes used in the construction of roads. The most common observation is that the data collected from these tests are often noisy and somewhat non-sinusoidal. This hampers accurate analysis of the data to obtain engineering insight. The goal of the work presented in this paper is to develop and compare automated evolutionary computational techniques to filter test noise in the collection of data for the HMA complex modulus test. The results showed that the Covariance Matrix Adaptation-Evolutionary Strategy (CMA-ES) approach is computationally efficient for filtering data obtained from the HMA complex modulus test.

Keywords: HMA, dynamic modulus, GA, evolutionarycomputation.

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7719 A Hybrid Feature Selection and Deep Learning Algorithm for Cancer Disease Classification

Authors: Niousha Bagheri Khulenjani, Mohammad Saniee Abadeh

Abstract:

Learning from very big datasets is a significant problem for most present data mining and machine learning algorithms. MicroRNA (miRNA) is one of the important big genomic and non-coding datasets presenting the genome sequences. In this paper, a hybrid method for the classification of the miRNA data is proposed. Due to the variety of cancers and high number of genes, analyzing the miRNA dataset has been a challenging problem for researchers. The number of features corresponding to the number of samples is high and the data suffer from being imbalanced. The feature selection method has been used to select features having more ability to distinguish classes and eliminating obscures features. Afterward, a Convolutional Neural Network (CNN) classifier for classification of cancer types is utilized, which employs a Genetic Algorithm to highlight optimized hyper-parameters of CNN. In order to make the process of classification by CNN faster, Graphics Processing Unit (GPU) is recommended for calculating the mathematic equation in a parallel way. The proposed method is tested on a real-world dataset with 8,129 patients, 29 different types of tumors, and 1,046 miRNA biomarkers, taken from The Cancer Genome Atlas (TCGA) database.

Keywords: Cancer classification, feature selection, deep learning, genetic algorithm.

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7718 Comparing the Performance of the Particle Swarm Optimization and the Genetic Algorithm on the Geometry Design of Longitudinal Fin

Authors: Hassan Azarkish, Said Farahat, S.Masoud H. Sarvari

Abstract:

In the present work, the performance of the particle swarm optimization and the genetic algorithm compared as a typical geometry design problem. The design maximizes the heat transfer rate from a given fin volume. The analysis presumes that a linear temperature distribution along the fin. The fin profile generated using the B-spline curves and controlled by the change of control point coordinates. An inverse method applied to find the appropriate fin geometry yield the linear temperature distribution along the fin corresponds to optimum design. The numbers of the populations, the count of iterations and time to convergence measure efficiency. Results show that the particle swarm optimization is most efficient for geometry optimization.

Keywords: Genetic Algorithm, Geometry Optimization, longitudinal Fin, Particle Swarm Optimization

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7717 A Genetic Based Algorithm to Generate Random Simple Polygons Using a New Polygon Merge Algorithm

Authors: Ali Nourollah, Mohsen Movahedinejad

Abstract:

In this paper a new algorithm to generate random simple polygons from a given set of points in a two dimensional plane is designed. The proposed algorithm uses a genetic algorithm to generate polygons with few vertices. A new merge algorithm is presented which converts any two polygons into a simple polygon. This algorithm at first changes two polygons into a polygonal chain and then the polygonal chain is converted into a simple polygon. The process of converting a polygonal chain into a simple polygon is based on the removal of intersecting edges. The experiments results show that the proposed algorithm has the ability to generate a great number of different simple polygons and has better performance in comparison to celebrated algorithms such as space partitioning and steady growth.

Keywords: Divide and conquer, genetic algorithm, merge polygons, Random simple polygon generation.

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7716 NSGA Based Optimal Volt / Var Control in Distribution System with Dispersed Generation

Authors: P. N. Hrisheekesha, Jaydev Sharma

Abstract:

In this paper, a method based on Non-Dominated Sorting Genetic Algorithm (NSGA) has been presented for the Volt / Var control in power distribution systems with dispersed generation (DG). Genetic algorithm approach is used due to its broad applicability, ease of use and high accuracy. The proposed method is better suited for volt/var control problems. A multi-objective optimization problem has been formulated for the volt/var control of the distribution system. The non-dominated sorting genetic algorithm based method proposed in this paper, alleviates the problem of tuning the weighting factors required in solving the multi-objective volt/var control optimization problems. Based on the simulation studies carried out on the distribution system, the proposed scheme has been found to be simple, accurate and easy to apply to solve the multiobjective volt/var control optimization problem of the distribution system with dispersed generation.

Keywords: Dispersed Generation, Distribution System, Non-Dominated Sorting Genetic Algorithm, Voltage / Reactive powercontrol.

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7715 Genetic Algorithm Based Deep Learning Parameters Tuning for Robot Object Recognition and Grasping

Authors: Delowar Hossain, Genci Capi

Abstract:

This paper concerns with the problem of deep learning parameters tuning using a genetic algorithm (GA) in order to improve the performance of deep learning (DL) method. We present a GA based DL method for robot object recognition and grasping. GA is used to optimize the DL parameters in learning procedure in term of the fitness function that is good enough. After finishing the evolution process, we receive the optimal number of DL parameters. To evaluate the performance of our method, we consider the object recognition and robot grasping tasks. Experimental results show that our method is efficient for robot object recognition and grasping.

Keywords: Deep learning, genetic algorithm, object recognition, robot grasping.

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7714 Binary Programming for Manufacturing Material and Manufacturing Process Selection Using Genetic Algorithms

Authors: Saleem Z. Ramadan

Abstract:

The material selection problem is concerned with the determination of the right material for a certain product to optimize certain performance indices in that product such as mass, energy density, and power-to-weight ratio. This paper is concerned about optimizing the selection of the manufacturing process along with the material used in the product under performance indices and availability constraints. In this paper, the material selection problem is formulated using binary programming and solved by genetic algorithm. The objective function of the model is to minimize the total manufacturing cost under performance indices and material and manufacturing process availability constraints.

Keywords: Optimization, Material selection, Process selection, Genetic algorithm.

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7713 A Multi-Level GA Search with Application to the Resource-Constrained Re-Entrant Flow Shop Scheduling Problem

Authors: Danping Lin, C.K.M. Lee

Abstract:

Re-entrant scheduling is an important search problem with many constraints in the flow shop. In the literature, a number of approaches have been investigated from exact methods to meta-heuristics. This paper presents a genetic algorithm that encodes the problem as multi-level chromosomes to reflect the dependent relationship of the re-entrant possibility and resource consumption. The novel encoding way conserves the intact information of the data and fastens the convergence to the near optimal solutions. To test the effectiveness of the method, it has been applied to the resource-constrained re-entrant flow shop scheduling problem. Computational results show that the proposed GA performs better than the simulated annealing algorithm in the measure of the makespan

Keywords: Resource-constrained, re-entrant, genetic algorithm (GA), multi-level encoding

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7712 Optimisation of Structural Design by Integrating Genetic Algorithms in the Building Information Modelling Environment

Authors: Tofigh Hamidavi, Sepehr Abrishami, Pasquale Ponterosso, David Begg

Abstract:

Structural design and analysis is an important and time-consuming process, particularly at the conceptual design stage. Decisions made at this stage can have an enormous effect on the entire project, as it becomes ever costlier and more difficult to alter the choices made early on in the construction process. Hence, optimisation of the early stages of structural design can provide important efficiencies in terms of cost and time. This paper suggests a structural design optimisation (SDO) framework in which Genetic Algorithms (GAs) may be used to semi-automate the production and optimisation of early structural design alternatives. This framework has the potential to leverage conceptual structural design innovation in Architecture, Engineering and Construction (AEC) projects. Moreover, this framework improves the collaboration between the architectural stage and the structural stage. It will be shown that this SDO framework can make this achievable by generating the structural model based on the extracted data from the architectural model. At the moment, the proposed SDO framework is in the process of validation, involving the distribution of an online questionnaire among structural engineers in the UK.

Keywords: Building Information Modelling, BIM, Genetic Algorithm, GA, architecture-engineering-construction, AEC, Optimisation, structure, design, population, generation, selection, mutation, crossover, offspring.

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7711 Development of Genetic-based Machine Learning for Network Intrusion Detection (GBML-NID)

Authors: Wafa' S.Al-Sharafat, Reyadh Naoum

Abstract:

Society has grown to rely on Internet services, and the number of Internet users increases every day. As more and more users become connected to the network, the window of opportunity for malicious users to do their damage becomes very great and lucrative. The objective of this paper is to incorporate different techniques into classier system to detect and classify intrusion from normal network packet. Among several techniques, Steady State Genetic-based Machine Leaning Algorithm (SSGBML) will be used to detect intrusions. Where Steady State Genetic Algorithm (SSGA), Simple Genetic Algorithm (SGA), Modified Genetic Algorithm and Zeroth Level Classifier system are investigated in this research. SSGA is used as a discovery mechanism instead of SGA. SGA replaces all old rules with new produced rule preventing old good rules from participating in the next rule generation. Zeroth Level Classifier System is used to play the role of detector by matching incoming environment message with classifiers to determine whether the current message is normal or intrusion and receiving feedback from environment. Finally, in order to attain the best results, Modified SSGA will enhance our discovery engine by using Fuzzy Logic to optimize crossover and mutation probability. The experiments and evaluations of the proposed method were performed with the KDD 99 intrusion detection dataset.

Keywords: MSSGBML, Network Intrusion Detection, SGA, SSGA.

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7710 Genetic Algorithm for Solving Non-Convex Economic Dispatch Problem

Authors: Navid Javidtash, Abdolmohamad Davodi, Mojtaba Hakimzadeh, Abdolreza Roozbeh

Abstract:

Economic dispatch (ED) is considered to be one of the key functions in electric power system operation. This paper presents a new hybrid approach based genetic algorithm (GA) to economic dispatch problems. GA is most commonly used optimizing algorithm predicated on principal of natural evolution. Utilization of chaotic queue with GA generates several neighborhoods of near optimal solutions to keep solution variation. It could avoid the search process from becoming pre-mature. For the objective of chaotic queue generation, utilization of tent equation as opposed to logistic equation results in improvement of iterative speed. The results of the proposed approach were compared in terms of fuel cost, with existing differential evolution and other methods in literature.

Keywords: Economic Dispatch(ED), Optimization, Fuel Cost, Genetic Algorithm (GA).

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7709 Optimizing of Fuzzy C-Means Clustering Algorithm Using GA

Authors: Mohanad Alata, Mohammad Molhim, Abdullah Ramini

Abstract:

Fuzzy C-means Clustering algorithm (FCM) is a method that is frequently used in pattern recognition. It has the advantage of giving good modeling results in many cases, although, it is not capable of specifying the number of clusters by itself. In FCM algorithm most researchers fix weighting exponent (m) to a conventional value of 2 which might not be the appropriate for all applications. Consequently, the main objective of this paper is to use the subtractive clustering algorithm to provide the optimal number of clusters needed by FCM algorithm by optimizing the parameters of the subtractive clustering algorithm by an iterative search approach and then to find an optimal weighting exponent (m) for the FCM algorithm. In order to get an optimal number of clusters, the iterative search approach is used to find the optimal single-output Sugenotype Fuzzy Inference System (FIS) model by optimizing the parameters of the subtractive clustering algorithm that give minimum least square error between the actual data and the Sugeno fuzzy model. Once the number of clusters is optimized, then two approaches are proposed to optimize the weighting exponent (m) in the FCM algorithm, namely, the iterative search approach and the genetic algorithms. The above mentioned approach is tested on the generated data from the original function and optimal fuzzy models are obtained with minimum error between the real data and the obtained fuzzy models.

Keywords: Fuzzy clustering, Fuzzy C-Means, Genetic Algorithm, Sugeno fuzzy systems.

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7708 Design of a Robust Controller for AGC with Combined Intelligence Techniques

Authors: R. N. Patel, S. K. Sinha, R. Prasad

Abstract:

In this work Artificial Intelligence (AI) techniques like Fuzzy logic, Genetic Algorithms and Particle Swarm Optimization have been used to improve the performance of the Automatic Generation Control (AGC) system. Instead of applying Genetic Algorithms and Particle swarm optimization independently for optimizing the parameters of the conventional AGC with PI controller, an intelligent tuned Fuzzy logic controller (acting as the secondary controller in the AGC system) has been designed. The controller gives an improved dynamic performance for both hydrothermal and thermal-thermal power systems under a variety of operating conditions.

Keywords: Artificial intelligence, Automatic generation control, Fuzzy control, Genetic Algorithm, Particle swarm optimization, Power systems.

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7707 Optimal Design of Substation Grounding Grid Based on Genetic Algorithm Technique

Authors: Ahmed Z. Gabr, Ahmed A. Helal, Hussein E. Said

Abstract:

With the incessant increase of power systems capacity and voltage grade, the safety of grounding grid becomes more and more prominent. In this paper, the designing substation grounding grid is presented by means of genetic algorithm (GA). This approach purposes to control the grounding cost of the power system with the aid of controlling grounding rod number and conductor lengths under the same safety limitations. The proposed technique is used for the design of the substation grounding grid in Khalda Petroleum Company “El-Qasr” power plant and the design was simulated by using CYMGRD software for results verification. The result of the design is highly complying with IEEE 80-2000 standard requirements.

Keywords: Genetic algorithm, optimum grounding grid design, power system analysis, power system protection, single layer model, substation.

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7706 Using Genetic Algorithms to Outline Crop Rotations and a Cropping-System Model

Authors: Nicolae Bold, Daniel Nijloveanu

Abstract:

The idea of cropping-system is a method used by farmers. It is an environmentally-friendly method, protecting the natural resources (soil, water, air, nutritive substances) and increase the production at the same time, taking into account some crop particularities. The combination of this powerful method with the concepts of genetic algorithms results into a possibility of generating sequences of crops in order to form a rotation. The usage of this type of algorithms has been efficient in solving problems related to optimization and their polynomial complexity allows them to be used at solving more difficult and various problems. In our case, the optimization consists in finding the most profitable rotation of cultures. One of the expected results is to optimize the usage of the resources, in order to minimize the costs and maximize the profit. In order to achieve these goals, a genetic algorithm was designed. This algorithm ensures the finding of several optimized solutions of cropping-systems possibilities which have the highest profit and, thus, which minimize the costs. The algorithm uses genetic-based methods (mutation, crossover) and structures (genes, chromosomes). A cropping-system possibility will be considered a chromosome and a crop within the rotation is a gene within a chromosome. Results about the efficiency of this method will be presented in a special section. The implementation of this method would bring benefits into the activity of the farmers by giving them hints and helping them to use the resources efficiently.

Keywords: Genetic algorithm, chromosomes, genes, cropping, agriculture.

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7705 Two Points Crossover Genetic Algorithm for Loop Layout Design Problem

Authors: Xu LiYun, Briand Florent, Fan GuoLiang

Abstract:

The loop-layout design problem (LLDP) aims at optimizing the sequence of positioning of the machines around the cyclic production line. Traffic congestion is the usual criteria to minimize in this type of problem, i.e. the number of additional cycles spent by each part in the network until the completion of its required routing sequence of machines. This paper aims at applying several improvements mechanisms such as a positioned-based crossover operator for the Genetic Algorithm (GA) called a Two Points Crossover (TPC) and an offspring selection process. The performance of the improved GA is measured using well-known examples from literature and compared to other evolutionary algorithms. Good results show that GA can still be competitive for this type of problem against more recent evolutionary algorithms.

Keywords: Crossover, genetic algorithm, layout design problem, loop-layout, manufacturing optimization.

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7704 Synthesis of Logic Circuits Using Fractional-Order Dynamic Fitness Functions

Authors: Cecília Reis, J. A. Tenreiro Machado, J. Boaventura Cunha

Abstract:

This paper analyses the performance of a genetic algorithm using a new concept, namely a fractional-order dynamic fitness function, for the synthesis of combinational logic circuits. The experiments reveal superior results in terms of speed and convergence to achieve a solution.

Keywords: Circuit design, fractional-order systems, genetic algorithms, logic circuits

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7703 Genetic Algorithm Parameters Optimization for Bi-Criteria Multiprocessor Task Scheduling Using Design of Experiments

Authors: Sunita Dhingra, Satinder Bal Gupta, Ranjit Biswas

Abstract:

Multiprocessor task scheduling is a NP-hard problem and Genetic Algorithm (GA) has been revealed as an excellent technique for finding an optimal solution. In the past, several methods have been considered for the solution of this problem based on GAs. But, all these methods consider single criteria and in the present work, minimization of the bi-criteria multiprocessor task scheduling problem has been considered which includes weighted sum of makespan & total completion time. Efficiency and effectiveness of genetic algorithm can be achieved by optimization of its different parameters such as crossover, mutation, crossover probability, selection function etc. The effects of GA parameters on minimization of bi-criteria fitness function and subsequent setting of parameters have been accomplished by central composite design (CCD) approach of response surface methodology (RSM) of Design of Experiments. The experiments have been performed with different levels of GA parameters and analysis of variance has been performed for significant parameters for minimisation of makespan and total completion time simultaneously.

Keywords: Multiprocessor task scheduling, Design of experiments, Genetic Algorithm, Makespan, Total completion time.

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7702 Design and Implementation a New Energy Efficient Clustering Algorithm using Genetic Algorithm for Wireless Sensor Networks

Authors: Moslem Afrashteh Mehr

Abstract:

Wireless Sensor Networks consist of small battery powered devices with limited energy resources. once deployed, the small sensor nodes are usually inaccessible to the user, and thus replacement of the energy source is not feasible. Hence, One of the most important issues that needs to be enhanced in order to improve the life span of the network is energy efficiency. to overcome this demerit many research have been done. The clustering is the one of the representative approaches. in the clustering, the cluster heads gather data from nodes and sending them to the base station. In this paper, we introduce a dynamic clustering algorithm using genetic algorithm. This algorithm takes different parameters into consideration to increase the network lifetime. To prove efficiency of proposed algorithm, we simulated the proposed algorithm compared with LEACH algorithm using the matlab

Keywords: Wireless Sensor Networks, Clustering, Geneticalgorithm, Energy Consumption

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7701 Cost Based Warranty Optimisation Using Genetic Algorithm

Authors: Dragan D. Stamenkovic, Vladimir M. Popovic

Abstract:

Warranty is a powerful marketing tool for the manufacturer and a good protection for both the manufacturer and the customer. However, warranty always involves additional costs to the manufacturer, which depend on product reliability characteristics and warranty parameters. This paper presents an approach to optimisation of warranty parameters for known product failure distribution to reduce the warranty costs to the manufacturer while retaining the promotional function of the warranty. Combination free replacement and pro-rata warranty policy is chosen as a model and the length of free replacement period and pro-rata policy period are varied, as well as the coefficients that define the pro-rata cost function. Multiparametric warranty optimisation is done by using genetic algorithm. Obtained results are guideline for the manufacturer to choose the warranty policy that minimises the costs and maximises the profit.

Keywords: costs, genetic algorithm, optimisation, warranty.

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7700 Predicting Dispersion Coefficient in Free-Flowing Zones of Rivers by Genetic Programming

Authors: Rajeev Ranjan Sahay

Abstract:

Transient storage zones along the flow paths of rivers have great influence on the dispersion of pollutants that are either accidentally or otherwise led into them. The speed with which these pollution clouds get transported and dispersed downstream is, to a large extent, explained by the longitudinal dispersion coefficients in the free-flowing zones of rivers (Kf). In the present work, a new empirical expression for Kf has been derived employing genetic programming (GP) on published dispersion data. The proposed expression uses few hydraulic and geometric characteristics of a river that are readily available to field engineers. Based on various performance indices, the proposed expression is found superior to other existing expression for Kf.

Keywords: Dispersion, parameter estimation, rivers, transient pollutant.

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7699 Accurate HLA Typing at High-Digit Resolution from NGS Data

Authors: Yazhi Huang, Jing Yang, Dingge Ying, Yan Zhang, Vorasuk Shotelersuk, Nattiya Hirankarn, Pak Chung Sham, Yu Lung Lau, Wanling Yang

Abstract:

Human leukocyte antigen (HLA) typing from next generation sequencing (NGS) data has the potential for applications in clinical laboratories and population genetic studies. Here we introduce a novel technique for HLA typing from NGS data based on read-mapping using a comprehensive reference panel containing all known HLA alleles and de novo assembly of the gene-specific short reads. An accurate HLA typing at high-digit resolution was achieved when it was tested on publicly available NGS data, outperforming other newly-developed tools such as HLAminer and PHLAT.

Keywords: Human leukocyte antigens, next generation sequencing, whole exome sequencing, HLA typing.

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7698 The Performance of Genetic Algorithm for Synchronized Chaotic Chen System in CDMA Satellite Channel

Authors: Salah Salmi, Karim Kemih, Malek Benslama

Abstract:

Synchronization is a difficult problem in CDMA satellite communications. Due to the influence of additive noise and fading in the mobile channel, it is not easy to keep up with the attenuation and offset. This paper considers a recently proposed approach to solve the problem of synchronization chaotic Chen system in CDMA satellite communication in the presence of constant attenuation and offset. An analytic algorithm that provides closed form channel and carrier offset estimates is presented. The principle of this approach is based on adding a compensation block before the receiver to compensate the distortion of the imperfect channel by using genetic algorithm. The resultants presented, show that the receiver is able to recover rapidly the synchronization with the transmitter.

Keywords: Chaotic Chen system, genetic algorithm, Synchronization, CDMA

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7697 A Genetic Algorithm Approach Considering Zero Injection Bus Constraint Modeling for Optimal Phasor Measurement Unit Placement

Authors: G. Chandana Sushma, T. R. Jyothsna

Abstract:

This paper presents optimal Phasor Measurement Unit (PMU) Placement in network using a genetic algorithm approach as it is infeasible and require high installation cost to place PMUs at every bus in network. This paper proposes optimal PMU allocation considering observability and redundancy utilizing Genetic Algorithm (GA) approach. The nonlinear constraints of buses are modeled to give accurate results. Constraints associated with Zero Injection (ZI) buses and radial buses are modeled to optimize number of locations for PMU placement. GA is modeled with ZI bus constraints to minimize number of locations without losing complete observability. Redundancy of every bus in network is computed to show optimum redundancy of complete system network. The performance of method is measured by Bus Observability Index (BOI) and Complete System Observability Performance Index (CSOPI). MATLAB simulations are carried out on IEEE -14, -30 and -57 bus-systems and compared with other methods in literature survey to show the effectiveness of the proposed approach.

Keywords: Constraints, genetic algorithm, observability, phasor measurement units, redundancy, synchrophasors, zero injection bus.

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7696 Auto Tuning PID Controller based on Improved Genetic Algorithm for Reverse Osmosis Plant

Authors: Jin-Sung Kim, Jin-Hwan Kim, Ji-Mo Park, Sung-Man Park, Won-Yong Choe, Hoon Heo

Abstract:

An optimal control of Reverse Osmosis (RO) plant is studied in this paper utilizing the auto tuning concept in conjunction with PID controller. A control scheme composing an auto tuning stochastic technique based on an improved Genetic Algorithm (GA) is proposed. For better evaluation of the process in GA, objective function defined newly in sense of root mean square error has been used. Also in order to achieve better performance of GA, more pureness and longer period of random number generation in operation are sought. The main improvement is made by replacing the uniform distribution random number generator in conventional GA technique to newly designed hybrid random generator composed of Cauchy distribution and linear congruential generator, which provides independent and different random numbers at each individual steps in Genetic operation. The performance of newly proposed GA tuned controller is compared with those of conventional ones via simulation.

Keywords: Genetic Algorithm, Auto tuning, Hybrid random number generator, Reverse Osmosis, PID controller

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