Search results for: Ahmad Saifizul Abdullah
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 603

Search results for: Ahmad Saifizul Abdullah

483 Design and Simulation Interface Circuit for Piezoresistive Accelerometers with Offset Cancellation Ability

Authors: Mohsen Bagheri, Ahmad Afifi

Abstract:

This paper presents a new method for read out of the piezoresistive accelerometer sensors. The circuit works based on Instrumentation amplifier and it is useful for reducing offset In Wheatstone Bridge. The obtained gain is 645 with 1μv/°c Equivalent drift and 1.58mw power consumption. A Schmitt trigger and multiplexer circuit control output node. a high speed counter is designed in this work .the proposed circuit is designed and simulated In 0.18μm CMOS technology with 1.8v power supply.

Keywords: Piezoresistive accelerometer, zero offset, Schmitt trigger, bidirectional reversible counter

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482 Change Point Analysis in Average Ozone Layer Temperature Using Exponential Lomax Distribution

Authors: Amjad Abdullah, Amjad Yahya, Bushra Aljohani, Amani S. Alghamdi

Abstract:

Change point detection is an important part of data analysis. The presence of a change point refers to a significant change in the behavior of a time series. In this article, we examine the detection of multiple change points of parameters of the exponential Lomax distribution, which is broad and flexible compared with other distributions while fitting data. We used the Schwarz information criterion and binary segmentation to detect multiple change points in publicly available data on the average temperature in the ozone layer. The change points were successfully located.

Keywords: Binary segmentation, change point, exponential Lomax distribution, information criterion.

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481 Rubric in Vocational Education

Authors: Azmanirah Ab Rahman, Jamil Ahmad, Ruhizan Muhammad Yasin

Abstract:

Rubric is a very important tool for teachers and students for a variety of purposes. Teachers use the rubric for evaluating student work while students use rubrics for self-assessment. Therefore, this paper was emphasized scoring rubric as a scoring tool for teachers in an environment of Competency Based Education and Training (CBET) in Malaysia Vocational College. A total of three teachers in the fields of electrical and electronics engineering were interviewed to identify how the use of rubrics practiced since vocational transformation implemented in 2012. Overall holistic rubric used to determine the performance of students in the skills area.

Keywords: Rubric, Vocational Education.

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480 Local Algorithm for Establishing a Virtual Backbone in 3D Ad Hoc Network

Authors: Alaa E. Abdallah, M. Bsoul, Emad E. Abdallah, Ahmad Al-Khasawneh, Muath Alzghool

Abstract:

Due to the limited lifetime of the nodes in ad hoc and sensor networks, energy efficiency needs to be an important design consideration in any routing algorithm. It is known that by employing a virtual backbone in a wireless network, the efficiency of any routing scheme for the network can be improved. One common design for routing protocols in mobile ad hoc networks is to use positioning information; we use the node-s geometric locations to introduce an algorithm that can construct the virtual backbone structure locally in 3D environment. The algorithm construction has a constant time.

Keywords: Virtual backbone, dominating set, UDG.

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479 Optimum Design of Attenuator of Spun-Bond Production System

Authors: Nasser Ghassembaglou, Abdullah Bolek, Oktay Yilmaz, Ertan Oznergiz, Hikmet Kocabas, Safak Yilmaz

Abstract:

Nanofibers are effective materials which have frequently been investigated to produce high quality air filters. As an environmental approach our aim is to achieve nanofibers by melting. In spun-bond systems extruder, spin-pump, nozzle package and attenuator are used. Molten polymer which flows from extruder is made steady by spin-pump. Regular melt passes through nozzle holes and forms fibers under high pressure. The fibers pulled from nozzle are shrunk to micron size by an attenuator; after solidification, they are collected on a conveyor. In this research different designs of attenuator system have been studied; and also CFD analysis has been done on these different designs. Afterwards, one of these designs tested and finally some optimizations have been done to reduce pressure loss and increase air velocity.

Keywords: Attenuator, nanofiber, spun-bond.

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478 Key Based Text Watermarking of E-Text Documents in an Object Based Environment Using Z-Axis for Watermark Embedding

Authors: Mussarat Abdullah, Fazal Wahab

Abstract:

Data hiding into text documents itself involves pretty complexities due to the nature of text documents. A robust text watermarking scheme targeting an object based environment is presented in this research. The heart of the proposed solution describes the concept of watermarking an object based text document where each and every text string is entertained as a separate object having its own set of properties. Taking advantage of the z-ordering of objects watermark is applied with the z-axis letting zero fidelity disturbances to the text. Watermark sequence of bits generated against user key is hashed with selected properties of given document, to determine the bit sequence to embed. Bits are embedded along z-axis and the document has no fidelity issues when printed, scanned or photocopied.

Keywords: Digital Watermarking, Object Based Environment, Watermark, z-ordering.

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477 Data Oriented Modeling of Uniform Random Variable: Applied Approach

Authors: Ahmad Habibizad Navin, Mehdi Naghian Fesharaki, Mirkamal Mirnia, Mohamad Teshnelab, Ehsan Shahamatnia

Abstract:

In this paper we introduce new data oriented modeling of uniform random variable well-matched with computing systems. Due to this conformity with current computers structure, this modeling will be efficiently used in statistical inference.

Keywords: Uniform random variable, Data oriented modeling, Statistical inference, Prodigraph, Statistically complete tree, Uniformdigital probability digraph, Uniform n-complete probability tree.

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476 Multi-threshold Approach for License Plate Recognition System

Authors: Siti Norul Huda Sheikh Abdullah, Farshid Pirahan Siah, Nor Hanisah Haji Zainal Abidin, Shahnorbanun Sahran

Abstract:

The objective of this paper is to propose an adaptive multi threshold for image segmentation precisely in object detection. Due to the different types of license plates being used, the requirement of an automatic LPR is rather different for each country. The proposed technique is applied on Malaysian LPR application. It is based on Multi Layer Perceptron trained by back propagation. The proposed adaptive threshold is introduced to find the optimum threshold values. The technique relies on the peak value from the graph of the number object versus specific range of threshold values. The proposed approach has improved the overall performance compared to current optimal threshold techniques. Further improvement on this method is in progress to accommodate real time system specification.

Keywords: Multi-threshold approach, license plate recognition system.

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475 Toxicity of Copper and Cadmium to Freshwater Fishes

Authors: M. Shuhaimi-Othman, Y. Nadzifah, A.K. Ahmad

Abstract:

Two freshwater fishes, Rasbora sumatrana (Cyprinidae) and Poecilia reticulata (guppy) (Poeciliidae) were exposed for a four-day period in the laboratory condition to a range of copper (Cu) and cadmium (Cd) concentrations. Mortality was assessed and median lethal concentrations (LC50) were calculated. LC50 increased with decrease in mean exposure times for both metals. For R. sumatrana, LC50s for 24, 48, 72 and 96 hours for Cu were 54.2, 30.3, 18.9 and 5.6 μg/L and for Cd 1440.2, 459.3, 392.3 and 101.6 μg/L respectively. For P. reticulata, LC50s for 24, 48, 72 and 96 hours for Cu were 348.9, 145.4, 61.3 and 37.9 μg/L and for Cd 8205.6, 2827.1, 405.8 and 168.1 μg/L, respectively. Results indicated that the Cu was more toxic than Cd to both fishes (Cu>Cd) and R. sumatrana was more sensitive than P. reticulata to the metals.

Keywords: Acute, heavy metals, LT50, toxicity

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474 An Incomplete Factorization Preconditioner for LMS Adaptive Filter

Authors: Shazia Javed, Noor Atinah Ahmad

Abstract:

In this paper an efficient incomplete factorization preconditioner is proposed for the Least Mean Squares (LMS) adaptive filter. The proposed preconditioner is approximated from a priori knowledge of the factors of input correlation matrix with an incomplete strategy, motivated by the sparsity patter of the upper triangular factor in the QRD-RLS algorithm. The convergence properties of IPLMS algorithm are comparable with those of transform domain LMS(TDLMS) algorithm. Simulation results show efficiency and robustness of the proposed algorithm with reduced computational complexity.

Keywords: Autocorrelation matrix, Cholesky's factor, eigenvalue spread, Markov input.

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473 Optimal Estimation of Surface Reflectance from Landsat TM Visible and Mid Infrared Data over Penang Island

Authors: H. S. Lim, M. Z. MatJafri, K. Abdullah, N. Mohd. Saleh

Abstract:

Retrieval of the surface reflectance is important in the remotely sensed data analysis to obtain the atmospheric reflectance or atmospheric correction. The relationship between visible and mid infrared reflectance over land was investigated and developed in this study. The surface reflectances of the two visible bands were measured using a handheld spectroradiometer collected around Penang Island. In this study, we use the assumption that the 2.1 μm band is not affected by aerosol and it is transparent to most aerosol types (except dust). Therefore the satellite observed signal is the same as the surface signal in 2.1 μm band. The correlation between the surface reflectance measured by the spectroradiometer in the blue and red region and the 2.1 μm observed by the satellite has been established. We investigate five dates of Landsat TM scenes in this study. The finding obtained by this study indicates that the surface reflectance can be retrieved from the 2.1 μm band.

Keywords: Surface Reflectance, Landsat TM, Aerosol, Spectroradiometer.

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472 Durability Properties of Foamed Concrete with Fiber Inclusion

Authors: Hanizam Awang, Muhammad Hafiz Ahmad

Abstract:

An experimental study was conducted on foamed concrete with synthetic and natural fibres consisting of AR-glas, polypropylene, steel, kenaf and oil palm fibre. The foamed concrete mixtures produced had a target density of 1000kg/m3 and a mix ratio of (1:1.5:0.45). The fibres were used as additives. The inclusion of fibre was maintained at a volumetric fraction of 0.25 and 0.4%. The water absorption, thermal and shrinkage were determined to study the effect of the fibre on the durability properties of foamed concrete. The results showed that AR-glass fibre has the lowest percentage value of drying shrinkage compared to others.

Keywords: Foamed concrete, Fibres, Durability.

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471 Learning Process Enhancement for Robot Behaviors

Authors: Saeed Mohammed Baneamoon, Rosalina Abdul Salam, Abdullah Zawawi Hj. Talib

Abstract:

Designing a simulated system and training it to optimize its tasks in simulated environment helps the designers to avoid problems that may appear when designing the system directly in real world. These problems are: time consuming, high cost, high errors percentage and low efficiency and accuracy of the system. The proposed system will investigate and improve the efficiency and accuracy of a simulated robot to choose correct behavior to perform its task. In this paper, machine learning, which uses genetic algorithm, is adopted. This type of machine learning is called genetic-based machine learning in which a distributed classifier system is used to improve the efficiency and accuracy of the robot. Consequently, it helps the robot to achieve optimal action.

Keywords: Machine Learning, Genetic-Based MachineLearning, Learning Classifier System, Behaviors.

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470 Minimizing Fresh and Wastewater Using Water Pinch Technique in Petrochemical Industries

Authors: W. Mughees, M. Al-Ahmad, M. Naeem

Abstract:

This research involves the design and analysis of pinch-based water/wastewater networks to minimize water utility in the petrochemical and petroleum industries. A study has been done on Tehran Oil Refinery to analyze feasibilities of regeneration, reuse and recycling of water network. COD is considered as a single key contaminant. Amount of freshwater was reduced about 149m3/h (43.8%) regarding COD. Re-design (or retrofitting) of water allocation in the networks was undertaken. The results were analyzed through graphical method and mathematical programming technique which clearly demonstrated that amount of required water would be determined by mass transfer of COD.

Keywords: Minimization, Water Pinch, Water Management, Pollution Prevention.

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469 Collaborative Research between Malaysian and Australian Universities on Learning Analytics: Challenges and Strategies

Authors: Z. Tasir, S. N. Kew, D. West, Z. Abdullah, D. Toohey

Abstract:

Research on Learning Analytics is progressively developing in the higher education field by concentrating on the process of students' learning. Therefore, a research project between Malaysian and Australian Universities was initiated in 2015 to look at the use of Learning Analytics to support the development of teaching practice. The focal point of this article is to discuss and share the experiences of Malaysian and Australian universities in the process of developing the collaborative research on Learning Analytics. Three aspects of this will be discussed: 1) Establishing an international research project and team members, 2) cross-cultural understandings, and 3) ways of working in relation to the practicalities of the project. This article is intended to benefit other researchers by highlighting the challenges as well as the strategies used in this project to ensure such collaborative research succeeds.

Keywords: Academic research project, collaborative research, cross-cultural understanding, international research project.

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468 A System to Integrate and Manipulate Protein Database Using BioPerl and XML

Authors: Zurinahni Zainol, Rosalina Abdul Salam, Rosni Abdullah, Nur'Aini, Wahidah Husain

Abstract:

The size, complexity and number of databases used for protein information have caused bioinformatics to lag behind in adapting to the need to handle this distributed information. Integrating all the information from different databases into one database is a challenging problem. Our main research is to develop a tool which can be used to access and manipulate protein information from difference databases. In our approach, we have integrated difference databases such as Swiss-prot, PDB, Interpro, and EMBL and transformed these databases in flat file format into relational form using XML and Bioperl. As a result, we showed this tool can search different sizes of protein information stored in relational database and the result can be retrieved faster compared to flat file database. A web based user interface is provided to allow user to access or search for protein information in the local database.

Keywords: Protein sequence database, relational database, integrated database.

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467 Implied Adjusted Volatility by Leland Option Pricing Models: Evidence from Australian Index Options

Authors: Mimi Hafizah Abdullah, Hanani Farhah Harun, Nik Ruzni Nik Idris

Abstract:

With the implied volatility as an important factor in financial decision-making, in particular in option pricing valuation, and also the given fact that the pricing biases of Leland option pricing models and the implied volatility structure for the options are related, this study considers examining the implied adjusted volatility smile patterns and term structures in the S&P/ASX 200 index options using the different Leland option pricing models. The examination of the implied adjusted volatility smiles and term structures in the Australian index options market covers the global financial crisis in the mid-2007. The implied adjusted volatility was found to escalate approximately triple the rate prior the crisis.

Keywords: Implied adjusted volatility, Financial crisis, Leland option pricing models.

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466 Curing Methods Yield Multiple Refractive Index of Benzocyclobutene Polymer Film

Authors: N.A.M. Yahya, W.H. Lim, S.W. Phang, H. Ahmad, R. Zakaria, F.R. Mahamd Adikan

Abstract:

Refractive index control of benzocyclobutene (BCB 4024-40) is achieved by facilitating different conditions during the thermal curing of BCB film. Refractive index (RI) change of 1.49% is obtained with curing of BCB film using an oven, while the RI change is 0.1% when the BCB is cured using a hotplate. The two different curing methods exhibit a temperature dependent refractive index change of the BCB photosensitive polymer. By carefully controlling the curing conditions, multiple layers of BCB with different RI can be fabricated, which can then be applied in the fabrication of optical waveguides.

Keywords: BCB 4024-40, curing method, multiple refractiveindex, polymers.

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465 Tsunami Modelling using the Well-Balanced Scheme

Authors: Ahmad Izani M. Ismail, Md. Fazlul Karim, Mai Duc Thanh

Abstract:

A well balanced numerical scheme based on stationary waves for shallow water flows with arbitrary topography has been introduced by Thanh et al. [18]. The scheme was constructed so that it maintains equilibrium states and tests indicate that it is stable and fast. Applying the well-balanced scheme for the one-dimensional shallow water equations, we study the early shock waves propagation towards the Phuket coast in Southern Thailand during a hypothetical tsunami. The initial tsunami wave is generated in the deep ocean with the strength that of Indonesian tsunami of 2004.

Keywords: Tsunami study, shallow water, conservation law, well-balanced scheme, topography. Subject classification: 86 A 05, 86 A 17.

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464 The Study on the Development of Ornamentation in the Architecture of Safavid Dynasty

Authors: N. Utaberta, H. Mamamni, M. Surat, A. I. Che-Ani, N.A.G. Abdullah

Abstract:

The architecture of Safavid Dynasty can be considered the epitome of Iranian architectural beauty. Safavid dynasty (1501- 1722 AC) along with Ottoman in Turkey and Mughal Empire in India were the three great Islamic nations of their time (1500 AC) often known as the last Islamic countries with international authority up to the 20th Century. This era approximately coincide with Renaissance in Europe. In this era, large European countries begin amassing power thanks to significant scientific, cultural and religious revolutions of that time and colonizing nations such as England, Spain and Portugal began to influence international trends with in an increasing while other non-industrial nations diminished. The main objective of this paper is to give a typological overview of the development of decoration and ornament in the architecture of Safafid Dynasty in Iran. It is expected that it can start a wider discussion to enrich this nation-s heritage and contribute to the development of Islamic ornament in general.

Keywords: Ornamentation, Architecture in Iran, Safavid Dynasty

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463 E-Appointment Scheduling (EAS)

Authors: Noraziah Ahmad, Roslina Mohd Sidek, Mohd Affendy Omardin

Abstract:

E-Appointment Scheduling (EAS) has been developed to handle appointment for UMP students, lecturers in Faculty of Computer Systems & Software Engineering (FCSSE) and Student Medical Center. The schedules are based on the timetable and university activities. Constraints Logic Programming (CLP) has been implemented to solve the scheduling problems by giving recommendation to the users in part of determining any available slots from the lecturers and doctors- timetable. By using this system, we can avoid wasting time and cost because this application will set an appointment by auto-generated. In addition, this system can be an alternative to the lecturers and doctors to make decisions whether to approve or reject the appointments.

Keywords: EAS, Constraint Logic Programming, PHP, Apache.

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462 Impact Modified Oil Palm Empty Fruit Bunch Fiber/Poly(Lactic) Acid Composite

Authors: Mohammad D. H. Beg, John O. Akindoyo, Suriati Ghazali, Abdullah A. Mamun

Abstract:

In this study, composites were fabricated from oil palm empty fruit bunch fiber and poly(lactic) acid by extrusion followed by injection moulding. Surface of the fiber was pre-treated by ultrasound in an alkali medium and treatment efficiency was investigated by scanning electron microscopy (SEM) analysis and Fourier transforms infrared spectrometer (FTIR). Effect of fiber treatment on composite was characterized by tensile strength (TS), tensile modulus (TM) and impact strength (IS). Furthermore, biostrong impact modifier was incorporated into the treated fiber composite to improve its impact properties. Mechanical testing showed an improvement of up to 23.5% and 33.6% respectively for TS and TM of treated fiber composite above untreated fiber composite. On the other hand incorporation of impact modifier led to enhancement of about 20% above the initial IS of the treated fiber composite.

Keywords: Fiber treatment, impact modifier, natural fibers, ultrasound.

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461 Transformation of Course Timetablinng Problem to RCPSP

Authors: M. Ahmad, M. Gourgand, C. Caux

Abstract:

The Resource-Constrained Project Scheduling Problem (RCPSP) is concerned with single-item or small batch production where limited resources have to be allocated to dependent activities over time. Over the past few decades, a lot of work has been made with the use of optimal solution procedures for this basic problem type and its extensions. Brucker and Knust[1] discuss, how timetabling problems can be modeled as a RCPSP. Authors discuss high school timetabling and university course timetabling problem as an example. We have formulated two mathematical formulations of course timetabling problem in a new way which are the prototype of single-mode RCPSP. Our focus is to show, how course timetabling problem can be transformed into RCPSP. We solve this transformation model with genetic algorithm.

Keywords: Course Timetabling, Integer programming, Combinatorial optimizations

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460 Goal-Based Request Cloud Resource Broker in Medical Application

Authors: Mohamad Izuddin Nordin, Azween Abdullah, Mahamat Issa Hassan

Abstract:

In this paper, cloud resource broker using goalbased request in medical application is proposed. To handle recent huge production of digital images and data in medical informatics application, the cloud resource broker could be used by medical practitioner for proper process in discovering and selecting correct information and application. This paper summarizes several reviewed articles to relate medical informatics application with current broker technology and presents a research work in applying goal-based request in cloud resource broker to optimize the use of resources in cloud environment. The objective of proposing a new kind of resource broker is to enhance the current resource scheduling, discovery, and selection procedures. We believed that it could help to maximize resources allocation in medical informatics application.

Keywords: Broker, Cloud Computing, Medical Informatics, Resources Discovery, Resource Selection.

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459 Analytical Solution for the Zakharov-Kuznetsov Equations by Differential Transform Method

Authors: Saeideh Hesam, Alireza Nazemi, Ahmad Haghbin

Abstract:

This paper presents the approximate analytical solution of a Zakharov-Kuznetsov ZK(m, n, k) equation with the help of the differential transform method (DTM). The DTM method is a powerful and efficient technique for finding solutions of nonlinear equations without the need of a linearization process. In this approach the solution is found in the form of a rapidly convergent series with easily computed components. The two special cases, ZK(2,2,2) and ZK(3,3,3), are chosen to illustrate the concrete scheme of the DTM method in ZK(m, n, k) equations. The results demonstrate reliability and efficiency of the proposed method.

Keywords: Zakharov-Kuznetsov equation, differential transform method, closed form solution.

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458 A Dose Distribution Approach Using Monte Carlo Simulation in Dosimetric Accuracy Calculation for Treating the Lung Tumor

Authors: Md Abdullah Al Mashud, M. Tariquzzaman, M. Jahangir Alam, Tapan Kumar Godder, M. Mahbubur Rahman

Abstract:

This paper presents a Monte Carlo (MC) method-based dose distributions on lung tumor for 6 MV photon beam to improve the dosimetric accuracy for cancer treatment. The polystyrene which is tissue equivalent material to the lung tumor density is used in this research. In the empirical calculations, TRS-398 formalism of IAEA has been used, and the setup was made according to the ICRU recommendations. The research outcomes were compared with the state-of-the-art experimental results. From the experimental results, it is observed that the proposed based approach provides more accurate results and improves the accuracy than the existing approaches. The average %variation between measured and TPS simulated values was obtained 1.337±0.531, which shows a substantial improvement comparing with the state-of-the-art technology.

Keywords: Lung tumor, Monte Carlo, polystyrene, elekta synergy, Monaco Planning System.

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457 Parametric Transition as a Spiral Curve and Its Application in Spur Gear Tooth with FEA

Authors: S. H. Yahaya, J. M. Ali, T.A. Abdullah

Abstract:

The exploration of this paper will focus on the Cshaped transition curve. This curve is designed by using the concept of circle to circle where one circle lies inside other. The degree of smoothness employed is curvature continuity. The function used in designing the C-curve is Bézier-like cubic function. This function has a low degree, flexible for the interactive design of curves and surfaces and has a shape parameter. The shape parameter is used to control the C-shape curve. Once the C-shaped curve design is completed, this curve will be applied to design spur gear tooth. After the tooth design procedure is finished, the design will be analyzed by using Finite Element Analysis (FEA). This analysis is used to find out the applicability of the tooth design and the gear material that chosen. In this research, Cast Iron 4.5 % Carbon, ASTM A-48 is selected as a gear material.

Keywords: Bézier-like cubic function, Curvature continuity, Cshapedtransition curve, Spur gear tooth.

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456 Understanding Socioscientific Issues in a Low Literate Society for the Achievement of the Millennium Development Goals

Authors: Jamil Mikhail Yahaya, Ahmad Nurulazam Md Zain, Mageswary Karpudewan

Abstract:

This paper highlights the controversial socioscientific issues and their misconceptions in Nigeria as well as in some other low literate societies around the world. It states the relevance of the issues or problems in Nigeria, which might be neutral or absent in other countries. The need to understand the issues and how such an understanding can contribute to the achievement of the Millennium Development Goals (MDGs) is also being discussed. The paper concludes by suggesting the responsibilities of science teachers to remove the misconceptions surrounding the socioscientific issues.

Keywords: Sosioscientific issues, Millennium development goals, Science teachers.

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455 Potential of Solar Energy in Zarqa Region

Authors: Ali M. Jawarneh, Ahmad S. AL-Shyyab

Abstract:

The purpose of this work is to present the potential of solar energy in Zarqa region. The solar radiation along year 2009 was obtained from Pyranometer which measures the global radiation over horizontal surfaces. Solar data in several different forms, over period of 5 minutes, hour-by-hour, daily and monthly data radiation have been presented. Briefly, the yearly global solar radiation in Zarqa is 7297.5 MJ/m2 (2027 kWh/m²) and the average annual solar radiation per day is 20 MJ/m2 (5.5 Kwh/m2). More specifically, the average annual solar radiation per day is 12.9 MJ/m2 (3.57 Kwh/m2) in winter and 25 MJ/m2 (7 Kwh/m2) in summer.

Keywords: Solar Energy, Pyranometer, Zarqa Region

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454 Multiple Sequence Alignment Using Optimization Algorithms

Authors: M. F. Omar, R. A. Salam, R. Abdullah, N. A. Rashid

Abstract:

Proteins or genes that have similar sequences are likely to perform the same function. One of the most widely used techniques for sequence comparison is sequence alignment. Sequence alignment allows mismatches and insertion/deletion, which represents biological mutations. Sequence alignment is usually performed only on two sequences. Multiple sequence alignment, is a natural extension of two-sequence alignment. In multiple sequence alignment, the emphasis is to find optimal alignment for a group of sequences. Several applicable techniques were observed in this research, from traditional method such as dynamic programming to the extend of widely used stochastic optimization method such as Genetic Algorithms (GAs) and Simulated Annealing. A framework with combination of Genetic Algorithm and Simulated Annealing is presented to solve Multiple Sequence Alignment problem. The Genetic Algorithm phase will try to find new region of solution while Simulated Annealing can be considered as an alignment improver for any near optimal solution produced by GAs.

Keywords: Simulated annealing, genetic algorithm, sequence alignment, multiple sequence alignment.

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