Search results for: Response surface methodology (RSM)
2666 Stimulus-Dependent Polyrhythms of Central Pattern Generator Hardware
Authors: Le Zhao, Alain Nogaret
Abstract:
We have built universal central pattern generator (CPG) hardware by interconnecting Hodgkin-Huxley neurons with reciprocally inhibitory synapses. We investigate the dynamics of neuron oscillations as a function of the time delay between current steps applied to individual neurons. We demonstrate stimulus dependent switching between spiking polyrhythms and map the phase portraits of the neuron oscillations to reveal the basins of attraction of the system. We experimentally study the dependence of the attraction basins on the network parameters: The neuron response time and the strength of inhibitory connections.
Keywords: Central pattern generator, winnerless competition principle.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 17502665 Water Depth and Optical Attenuation Characteristics of Natural Water Reservoirs nearby Kolkata City Assessed from Hyperion Hyperspectral and LISS-3 Multispectral Images
Authors: Barun Raychaudhuri
Abstract:
A methodology is proposed for estimating the optical attenuation and proportional depth variation of shallow inland water. The process is demonstrated with EO-1 Hyperion hyperspectral and IRS-P6 LISS-3 multispectral images of Kolkata city nearby area centered around 22º33′ N 88º26′ E. The attenuation coefficient of water was found to change with fine resolution of wavebands and in presence of suspended organic matter in water.
Keywords: Hyperion, hyperspectral, Kolkata, water depth.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19922664 The Study of Super Hydrophobic Surfaces Using High Speed Shadowgraphy
Authors: D. Jasikova, M. Kotek, V. Kopecky
Abstract:
The aim of this article is the measurement of the basic characteristic of superhydrophobic surfaces using high speed shadowgraphy. Here we describe the novel patented system for the industrial production of superhydrophobic surfaces. These surfaces were investigated with two optically based measurement methods: impinging drop and inclined wall. The results of the visualization and analysis help to state the suitable sample with superhydrophobic properties for mathematic simulation.
Keywords: Antipearl effect, contact angle, hydrophobic, impinging drop, inclined wall, measurement, plasma, shadowgraphy, superhydrophobic surface.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 24572663 A Digitally Programmable Voltage-mode Multifunction Biquad Filter with Single-Output
Authors: C. Ketviriyakit, W. Kongnun, C. Chanapromma, P. Silapan
Abstract:
This article proposes a voltage-mode multifunction filter using differential voltage current controllable current conveyor transconductance amplifier (DV-CCCCTA). The features of the circuit are that: the quality factor and pole frequency can be tuned independently via the values of capacitors: the circuit description is very simple, consisting of merely 1 DV-CCCCTA, and 2 capacitors. Without any component matching conditions, the proposed circuit is very appropriate to further develop into an integrated circuit. Additionally, each function response can be selected by suitably selecting input signals with digital method. The PSpice simulation results are depicted. The given results agree well with the theoretical anticipation.Keywords: DV-CCCCTA, Voltage-mode, Multifunction filter
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 13562662 Measurement of Rheologic Properties of Soft Tissue (Muscle Tissue) by Myotonometer
Authors: Petr Šifta, Václav Bittner, Martin Kysela, Matěj Kolář
Abstract:
The purpose of the research described in this work is to answer how to measure the rheologic (viscoelastic) properties tendo–deformational characteristics of soft tissue. The method would also resemble muscle palpation examination as it is known in clinical practice. For this purpose, an instrument with the working name “myotonometer” has been used. At present, there is lack of objective methods for assessing the muscle tone by viscous and elastic properties of soft tissue. That is why we decided to focus on creating or finding quantitative and qualitative methodology capable to specify muscle tone.
Keywords: Rheologicproperties, tendo–deformational characteristics, viscosity, elasticity, hypertonus, spasticity.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19942661 Chinese Tourists’s Behaviors towards Travel and Shopping in Bangkok
Authors: Sasitorn Chetanont
Abstract:
The objectives of this study are to study Chinese tourist’s Behaviors towards travel and shopping in Bangkok. The research methodology was a quantitative research. The sample of this research was 400 Chinese tourists in Bangkok chosen by the accidental sampling and the purposive sampling. Inferential Statistics Analysis by using the Chi-square statistics. As for the results of this study the researcher found that differences between personal, social and cultural information, i.e., gender, age, place of residence, educational level, occupation, income, family, and main objectives of tourism with behaviors of Chinese tourists in Bangkok towards travel and shopping in Bangkok.Keywords: Tourists’ behavior, Chinese tourists, travelling, expenses in travels.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 46902660 Detection of Black Holes in MANET Using Collaborative Watchdog with Fuzzy Logic
Authors: Y. Harold Robinson, M. Rajaram, E. Golden Julie, S. Balaji
Abstract:
Mobile ad hoc network (MANET) is a self-configuring network of mobile node connected without wires. A Fuzzy Logic Based Collaborative watchdog approach is used to reduce the detection time of misbehaved nodes and increase the overall truthfulness. This methodology will increase the secure efficient routing by detecting the Black Holes attacks. The simulation results proved that this method improved the energy, reduced the delay and also improved the overall performance of the detecting black hole attacks in MANET.
Keywords: MANET, collaborative watchdog, fuzzy logic, AODV.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 13492659 Cost of Road Traffic Accidents in Egypt
Authors: Mohamed A. Ismail, Samar M. M. Abdelmageed
Abstract:
The main objective of this paper is to estimate the cost of road traffic accidents in Egypt. The Human Capital (HC) approach, specifically the Gross-Loss-of-Output methodology, is adopted for estimation. Moreover, cost values obtained by previous national literature are updated using the inflation rates. The results indicate an estimated cost of road traffic accidents in Egypt of approximately 10 billion Egyptian Pounds (about $US 1.8 billion) for the year 2008. In addition, it is expected that this cost will rise in 2009 to 11.8 billion Egyptian Pounds (about $US 2.1 billion).
Keywords: Cost, Gross-Loss-of-Output, Human CapitalApproach, Road Traffic Accidents.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 37802658 Challenges and Opportunities for Biodiversity Conservation and Sustainable Development of Ecotourism in Lalzi Bay, Durres County, Albania - Today's Science for Tomorrow's Management. A Methodology Guide with a Concrete Example by Lalzi Bay, Durres County, Albania
Authors: Arnisa Lushaj, Arvjen Lushaj, Sunitha N. Seenappa, Georgia Butina-Watson, Bashkim Lushaj, Vera Malsia, Dodë Doçi, Mercedes Hunt, Ervin Buçpapaj
Abstract:
Tourism and coastal lines are the business sectors since centuries especially in the European Nations and Albania is one such spots. However, in recent decades tourism is experienced as vulnerability of the surrounding ecological conditions of air, soil, water, land and the communities that are dependant and sharing the ecosystem among flora and fauna. Experts opine that apart from the maintenance of near-originality of ecological biodiversity the tourism rather known as ecotourism an indigenous socio-cultural maintenance of indigenous/traditional knowledge of the local people must be well cared in order to sustain on sustainable grounds. As a general tendency, growth of tourism has been affected by the deterioration in the economic conditions on one aspect and unsustainable ecological areas affected since human interventions earlier to this has negative impact on futuristic tourist spots. However, tourism in Albania as of now is 11% of GDP and coastal regions accounting to 2-4%. An amicable Mediterranean climate with 300 sunny days similar parameters of Greece and Spain throws up sustainable ecotourism in future decades provided public services namely, transportation, road safety, lodging, food availability, recreational regiments, banking accessibility are as per the World Tourism Organizations- protocols. Thus as of Albanian situation, classification of ecotourism activities to safe-guard the localities with its maintenance of ecological land, water and climate has become a paramount importance with a wanting and satisfactory options through harnessing human energy for profit and fitness of ecological flora and fauna. A check on anthropogenic wastes and their safer utilizations inclusive of agricultural and industrial operations in line with Lalzi Bay Coastal Line are of utmost importance for the reason that the Adriatic Sea Coast is the one long stretch of Albanian Lifeline. The present work is based on the methodology of the sustainable management of the same issue.Keywords: Albania, ecotourism, Lalzi Bay, sustainability.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20692657 Design of Variable Fractional-Delay FIR Differentiators
Authors: Jong-Jy Shyu, Soo-Chang Pei, Min-Han Chang
Abstract:
In this paper, the least-squares design of variable fractional-delay (VFD) finite impulse response (FIR) digital differentiators is proposed. The used transfer function is formulated so that Farrow structure can be applied to realize the designed system. Also, the symmetric characteristics of filter coefficients are derived, which leads to the complexity reduction by saving almost a half of the number of coefficients. Moreover, all the elements of related vectors or matrices for the optimal process can be represented in closed forms, which make the design easier. Design example is also presented to illustrate the effectiveness of the proposed method.
Keywords: Differentiator, variable fractional-delay filter, FIR filter, least-squares method, Farrow structure.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 14142656 Performance Assessment and Optimization of the After-Sale Networks
Authors: H. Izadbakhsh, M.Hour Ali, A. Amirkhani, A. Montazeri, M. Saberi
Abstract:
The after–sales activities are nowadays acknowledged as a relevant source of revenue, profit and competitive advantage in most manufacturing industries. Top and middle management, therefore, should focus on the definition of a structured business performance measurement system for the after-sales business. The paper aims at filling this gap, and presents an integrated methodology for the after-sales network performance measurement, and provides an empirical application to automotive case companies and their official service network. This is the first study that presents an integrated multivariate approach for total assessment and improvement of after-sale services.Keywords: Data Envelopment Analysis (DEA), Principal Component Analysis (PCA), Automotive companies, After-sale services.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 18842655 Frequency-Domain Design of Fractional-Order FIR Differentiators
Authors: Wei-Der Chang, Dai-Ming Chang, Eri-Wei Chiang, Chia-Hung Lin, Jian-Liung Chen
Abstract:
In this paper, a fractional-order FIR differentiator design method using the differential evolution (DE) algorithm is presented. In the proposed method, the FIR digital filter is designed to meet the frequency response of a desired fractal-order differentiator, which is evaluated in the frequency domain. To verify the design performance, another design method considered in the time-domain is also provided. Simulation results reveal the efficiency of the proposed method.Keywords: Fractional-order differentiator, FIR digital filter, Differential evolution algorithm.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 22492654 An Interval-Based Multi-Attribute Decision Making Approach for Electric Utility Resource Planning
Authors: M. Sedighizadeh, A. Rezazadeh
Abstract:
This paper presents an interval-based multi-attribute decision making (MADM) approach in support of the decision process with imprecise information. The proposed decision methodology is based on the model of linear additive utility function but extends the problem formulation with the measure of composite utility variance. A sample study concerning with the evaluation of electric generation expansion strategies is provided showing how the imprecise data may affect the choice toward the best solution and how a set of alternatives, acceptable to the decision maker (DM), may be identified with certain confidence.Keywords: Decision Making, Power Generation, ElectricUtilities, Resource Planning.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 15752653 Accurate Crosstalk Analysis for RLC On-Chip VLSI Interconnect
Authors: Susmita Sahoo, Madhumanti Datta, Rajib Kar
Abstract:
This work proposes an accurate crosstalk noise estimation method in the presence of multiple RLC lines for the use in design automation tools. This method correctly models the loading effects of non switching aggressors and aggressor tree branches using resistive shielding effect and realistic exponential input waveforms. Noise peak and width expressions have been derived. The results obtained are at good agreement with SPICE results. Results show that average error for noise peak is 4.7% and for the width is 6.15% while allowing a very fast analysis.
Keywords: Crosstalk, distributed RLC segments, On-Chip interconnect, output response, VLSI, noise peak, noise width.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16442652 A New Model for e-CRM in e-Commerce using Live-Operator
Authors: Samin Jirehbandei, Alireza Nemaney Pour
Abstract:
Bythe development of the Internet, e-commerce has got very popular between organizations. E-commerce means buying and selling products and services over the Internet. One of the challenging issues in e-commerce is how to attract the customers and how to satisfy them. Therefore, it is important to keep good relationship with the customers. This paper proposes a new model to increase the customer satisfaction by introducing live-operator. Live-operator is a system which is involved both with the customers and the organization.In this system the customers feelthatthey receive the service directly from the organization. This model decreases the response time and the customer loss. Moreover, it increases customer trust and the ability of organizations.Keywords: Customer, Customer Satisfaction, e-Commerce, e-CRM, Live-Operator, Organization
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 23922651 Comparing Transformational Leadership in Successful and Unsuccessful Companies
Authors: Gh. Jandaghi, H. Zarei Matin, A. Farjami
Abstract:
In this article, while it is attempted to describe the problem and its importance, transformational leadership is studied by considering leadership theories. Issues such as the definition of transformational leadership and its aspects are compared on the basis of the ideas of various connoisseurs and then it (transformational leadership) is examined in successful and unsuccessful companies. According to the methodology, the method of research, hypotheses, population and statistical sample are investigated and research findings are analyzed by using descriptive and inferential statistical methods in the framework of analytical tables. Finally, our conclusion is provided by considering the results of statistical tests. The final result shows that transformational leadership is significantly higher in successful companies than unsuccessful ones P<0.0001).Keywords: Idealized influence, individualized considerations, inspirational motivation, intellectual stimulation, transformational leadership
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 46152650 Breast Cancer Treatment Evaluation based on Mammographic and Echographic Distance Computing
Authors: M. Caramihai, Irina Severin, H. Balan, A. Blidaru, V. Balanica
Abstract:
Accurate assessment of the primary tumor response to treatment is important in the management of breast cancer. This paper introduces a new set of treatment evaluation indicators for breast cancer cases based on the computational process of three known metrics, the Euclidian, Hamming and Levenshtein distances. The distance principals are applied to pairs of mammograms and/or echograms, recorded before and after treatment, determining a reference point in judging the evolution amount of the studied carcinoma. The obtained numerical results are indeed very transparent and indicate not only the evolution or the involution of the tumor under treatment, but also a quantitative measurement of the benefit in using the selected method of treatment.Keywords: Breast cancer, Distance metrics, Cancer treatment evaluation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 15582649 Determination of Optical Constants of Semiconductor Thin Films by Ellipsometry
Authors: Aïssa Manallah, Mohamed Bouafia
Abstract:
Ellipsometry is an optical method based on the study of the behavior of polarized light. The light reflected on a surface induces a change in the polarization state which depends on the characteristics of the material (complex refractive index and thickness of the different layers constituting the device). The purpose of this work is to determine the optical properties of semiconductor thin films by ellipsometry. This paper describes the experimental aspects concerning the semiconductor samples, the SE400 ellipsometer principle, and the results obtained by direct measurements of ellipsometric parameters and modelling using appropriate software.Keywords: Ellipsometry, optical constants, semiconductors, thin films.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 13362648 The Investigations of Water-ethanol Mixture by Monte Carlo Method
Authors: Atamas N. A., Atamas A. A.
Abstract:
Energetic and structural results for ethanol-water mixtures as a function of the mole fraction were calculated using Monte Carlo methodology. Energy partitioning results obtained for equimolar water-ethanol mixture and ether organic liquids are compared. It has been shown that at xet=0.22 the RDFs for waterethanol and ethanol-ethanol interactions indicated strong hydrophobic interactions between ethanol molecules and the local structure of solution is less structured at this concentration as at ether ones. Results obtained for ethanol-water mixture as a function of concentration are in good agreement with the experimental data.
Keywords: Ethanol, molecular liquids, Monte Carlo, water, thermodynamics.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 22392647 Analyzing and Determining the Ideal Response Force for Combatting Terrorist Groups
Authors: Erhan Turgut, Salih Ergün, Abdülkadir Öz
Abstract:
Terror is a modern war strategy which uses violence as a means of communication in order to achieve political objectives. In today’s security environment narrowing the propaganda field of terrorist organization is the primary goal for the security forces. In this sense, providing and maintaining public support is the most necessary ability for security units. Rather than enemy and threat-oriented approach, homeland security oriented approach is essential to ensure public support. In this study, terror assumed as a homeland security issue and assigning the law enforcement forces with military status is analyzed.Keywords: Terrorism, Counter-terrorism, Military Status Law-enforcement.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 21932646 Retranslation of Orientalism: Reading Said in Arabic
Authors: Fadil Elmenfi
Abstract:
Edward Said in his book Culture and Imperialism devotes the introduction to the Arabic translation. He claims that the fading echo of Orientalism in the Arab world is unlike the positive reflections of its counterpart elsewhere in the world. The probable reason behind his inquiry would be that the methodology Abu Deeb applied in translating Said's book contributed to the book having the limited impact which Said is referring to. The paper adds new insights to the body of theory and the effectiveness of the performance of translation from culture to culture. It presents a survey that can provide the reader with an overview of Said's Orientalism and the two Arabic translations of the book. It investigates some of the problems of translating cultural texts, more specifically translating features of Said's style.
Keywords: Orientalism, Retranslation, Arabic Language, Muhammad Enani, Kamal Abu Deeb, Edward Said.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 42112645 Processing Design of Miniature Casting Incorporating Stereolithography Technologies
Authors: Pei-Hsing Huang, Wei-Ju Huang
Abstract:
Investment casting is commonly used in the production of metallic components with complex shapes, due to its high dimensional precision, good surface finish, and low cost. However, the process is cumbersome, and the period between trial casting and final production can be very long, thereby limiting business opportunities and competitiveness. In this study, we replaced conventional wax injection with stereolithography (SLA) 3D printing to speed up the trial process and reduce costs. We also used silicone molds to further reduce costs to avoid the high costs imposed by photosensitive resin.
Keywords: Investment casting, stereolithography, wax molding, 3D printing.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 14862644 Comparative Approach of Measuring Price Risk on Romanian and International Wheat Market
Authors: Larisa N. Pop, Irina M. Ban
Abstract:
This paper aims to present the main instruments used in the economic literature for measuring the price risk, pointing out on the advantages brought by the conditional variance in this respect. The theoretical approach will be exemplified by elaborating an EGARCH model for the price returns of wheat, both on Romanian and on international market. To our knowledge, no previous empirical research, either on price risk measurement for the Romanian markets or studies that use the ARIMA-EGARCH methodology, have been conducted. After estimating the corresponding models, the paper will compare the estimated conditional variance on the two markets.Keywords: conditional variance, GARCH models, price risk, volatility
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 14482643 Investigation of Undular Hydraulic Jump over Smooth Beds
Authors: F. Rostami, M. Shahrokhi, M. A. Md Said, S.R. Sabbagh-Yazdi
Abstract:
Undular hydraulic jumps are illustrated by a smooth rise of the free surface followed by a train of stationary waves. They are sometimes experienced in natural waterways and rivers. The characteristics of undular hydraulic jumps are studied here. The height, amplitude and the main characteristics of undular jump is depended on the upstream Froude number and aspect ratio. The experiments were done on the smooth bed flume. These results compared with other researches and the main characteristics of the undular hydraulic jump were studied in this article.Keywords: Undular Hydraulic Jump, low Froude Number, wave characteristics
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19742642 Evaluation of Risks in New Product Innovation
Authors: Emre Alptekin, Damla Yalçınyiğit, Gülfem Alptekin
Abstract:
In highly competitive environments, a growing number of companies must regularly launch new products speedily and successfully. A company-s success is based on the systematic, conscious product designing method which meets the market requirements and takes risks as well as resources into consideration. Research has found that developing and launching new products are inherently risky endeavors. Hence in this research, we aim at introducing a risk evaluation framework for the new product innovation process. Our framework is based on the fuzzy analytical hierarchy process (FAHP) methodology. We have applied all the stages of the framework on the risk evaluation process of a pharmaceuticals company.Keywords: Evaluation, risks, product innovation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 14912641 Optimizing Machine Vision System Setup Accuracy by Six-Sigma DMAIC Approach
Authors: Joseph C. Chen
Abstract:
Machine vision system provides automatic inspection to reduce manufacturing costs considerably. However, only a few principles have been found to optimize machine vision system and help it function more accurately in industrial practice. Mostly, there were complicated and impractical design techniques to improve the accuracy of machine vision system. This paper discusses implementing the Six Sigma Define, Measure, Analyze, Improve, and Control (DMAIC) approach to optimize the setup parameters of machine vision system when it is used as a direct measurement technique. This research follows a case study showing how Six Sigma DMAIC methodology has been put into use.
Keywords: DMAIC, machine vision system, process capability, Taguchi parameter design.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 12512640 Properties of Adipose Tissue Derived Mesenchymal Stem Cells with Long-Term Cryopreservation
Authors: Jienny Lee, In-Soo Cho, Sang-Ho Cha
Abstract:
Adult mesenchymal stem cells (MSCs) have been investigated using preclinical approaches for tissue regeneration. Porcine MSCs (pMSCs) are capable of growing and attaching to plastic with a fibroblast-like morphology and then differentiating into bone, adipose, and cartilage tissues in vitro. This study was conducted to investigate the proliferating abilities, differentiation potentials, and multipotency of miniature pig adipose tissue-derived MSCs (mpAD-MSCs) with or without long-term cryopreservation, considering that cryostorage has the potential for use in clinical applications. After confirming the characteristics of the mpAD-MSCs, we examined the effect of long-term cryopreservation (> 2 years) on expression of cell surface markers (CD34, CD90 and CD105), proliferating abilities (cumulative population doubling level, doubling time, colony-forming unit, and MTT assay) and differentiation potentials into mesodermal cell lineages. As a result, the expression of cell surface markers is similar between thawed and fresh mpAD-MSCs. However, long-term cryopreservation significantly lowered the differentiation potentials (adipogenic, chondrogenic, and osteogenic) of mpAD-MSCs. When compared with fresh mpAD-MSCs, thawed mpAD-MSCs exhibited lower expression of mesodermal cell lineage-related genes such as peroxisome proliferator-activated receptor-g2, lipoprotein lipase, collagen Type II alpha 1, osteonectin, and osteocalcin. Interestingly, long-term cryostoraged mpAD-MSCs exhibited significantly higher cell viability than the fresh mpAD-MSCs. Long-term cryopreservation induced a 30% increase in the cell viability of mpAD-MSCs when compared with the fresh mpAD-MSCs at 5 days after thawing. However, long-term cryopreservation significantly lowered expression of stemness markers such as Oct3/4, Sox2, and Nanog. Furthermore, long-term cryopreservation negatively affected expression of senescence-associated genes such as telomerase reverse transcriptase and heat shock protein 90 of mpAD-MSCs when compared with the fresh mpAD-MSCs. The results from this study might be important for the successful application of MSCs in clinical trials after long-term cryopreservation.Keywords: Mesenchymal stem cells, Cryopreservation, Stemness, Senescence.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 21022639 Genetic Algorithm and Padé-Moment Matching for Model Order Reduction
Authors: Shilpi Lavania, Deepak Nagaria
Abstract:
A mixed method for model order reduction is presented in this paper. The denominator polynomial is derived by matching both Markov parameters and time moments, whereas numerator polynomial derivation and error minimization is done using Genetic Algorithm. The efficiency of the proposed method can be investigated in terms of closeness of the response of reduced order model with respect to that of higher order original model and a comparison of the integral square error as well.
Keywords: Model Order Reduction (MOR), control theory, Markov parameters, time moments, genetic algorithm, Single Input Single Output (SISO).
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 35322638 Response of the Residential Building Structureon Load Technical Seismicity due to Mining Activities
Authors: V. Salajka, Z. Kaláb, J. Kala, P. Hradil
Abstract:
In the territories where high-intensity earthquakes are frequent is paid attention to the solving of the seismic problems. In the paper are described two computational model variants based on finite element method of the construction with different subsoil simulation (rigid or elastic subsoil) is used. For simulation and calculations program system based on method final elements ANSYS was used. Seismic responses calculations of residential building structure were effected on loading characterized by accelerogram for comparing with the responses spectra method.Keywords: Accelerogram, ANSYS, mining induced seismic, residential building structure, spectra, subsoil.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 15352637 Flow and Heat Transfer of a Nanofluid over a Shrinking Sheet
Authors: N. Bachok, N. L. Aleng, N. M. Arifin, A. Ishak, N. Senu
Abstract:
The problem of laminar fluid flow which results from the shrinking of a permeable surface in a nanofluid has been investigated numerically. The model used for the nanofluid incorporates the effects of Brownian motion and thermophoresis. A similarity solution is presented which depends on the mass suction parameter S, Prandtl number Pr, Lewis number Le, Brownian motion number Nb and thermophoresis number Nt. It was found that the reduced Nusselt number is decreasing function of each dimensionless number.
Keywords: Boundary layer, Nanofluid, Shrinking sheet, Brownian motion, Thermophoresis, Similarity solution.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2805