Search results for: availability Gumbel-Hougaard family copula
306 Conventional Synthesis and Characterization of Zirconium Molybdate, Nd2Zr3(MoO4)9
Authors: G. Çelik Gül, F. Kurtuluş
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Rare earths containing complex metal oxides have drawn much attention due to physical, chemical and optical properties which make them feasible in so many areas such as non-linear optical materials and ion exchanger. We have researched a systematic study to obtain rare earth containing zirconium molybdate compound, characterization, investigation of crystal system and calculation of unit cell parameters. After a successful synthesis of Nd2Zr3(MoO4)9 which is a member of rare earth metal containing complex oxides family, X-ray diffraction (XRD), High Score Plus/Rietveld refinement analysis, and Fourier Transform Infrared Spectroscopy (FTIR) were completed to determine the crystal structure. Morphological properties and elemental composition were determined by scanning electron microscopy (SEM) and energy dispersive X-ray (EDX) analysis. Thermal properties were observed via Thermogravimetric-differential thermal analysis (TG/DTA).Keywords: Nd2Zr3(MoO4)9, solid state synthesis, powder x-ray diffraction, zirconium molybdates.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1091305 Assessing the Competence of Junior Paediatric Doctors in Managing Paediatric Diabetic Ketoacidosis: An Exploration Across Paediatric Care Units in UK
Authors: Mai Ali
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Advancing beyond the junior stage of a paediatrician’s career is a crucial step where they accumulate essential skills and knowledge. This process prepares them for the challenges they will encounter throughout their profession, particularly in dealing with paediatric emergencies. This can be especially demanding for trainees specializing in fields like endocrinology, particularly in the management of Diabetic Ketoacidosis (DKA) in the UK. In different societal contexts, junior doctors, whether specializing in paediatrics or other medical fields, are generally expected to possess a fundamental level of knowledge and skills necessary for managing DKA emergencies. These physicians consistently concurred in recognizing prevalent problems in the healthcare facilities they examined. Such issues include the lack of established guidelines for DKA treatment and the inadequate availability of comprehensive training opportunities. The abstract underscores the critical importance of junior paediatricians acquiring expertise in managing paediatric emergencies, with a specific focus on DKA. Commonly, issues like the lack of standardized protocols and training deficiencies are recurring themes across healthcare facilities. This research proposal aims to conduct a thematic analysis of the proficiency of paediatric trainees in the United Kingdom when handling DKA in various clinical contexts. The primary goal is to assess their competency and suggest effective strategies for comprehensive DKA training improvement.
Keywords: DKA management, junior paediatricians, level of competence, standardized protocols.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 47304 The Influence of Socio-Economic Backgrounds towards Satisfaction with Student Housing Facilities
Authors: Nurul ‘Ulyani Mohd Najib, Nor’ Aini Yusof, Zulkifli Osman
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Studies on residential satisfaction have been actively discussed under family house setting. However, limited studies have been conducted on student residential satisfaction. This study is an attempt to fill the research gap. It focuses on the influence of socioeconomic on students- satisfaction with the universities- student housing facilities. The students who stayed at the on-campus student housing were the respondents. This study employed two-stage cluster sampling method in classifying the respondents. Self-administered questionnaires were distributed face-to-face to the students. In general, it is confirmed that students- socio-economic backgrounds have influence on the students- satisfaction with their housing facilities. The main influential factors were the students- economic status, sense of sharing, and ethnicity of their roommates. Furthermore, this study could also provide a useful feedback for the universities in order to improve their student housing facilities.Keywords: Malaysia, Socio-economic, Student housing, Student residential satisfaction
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2511303 Addictive Use Due to Personality: Focused on Big Five Personality Traits and Game Addiction
Authors: Eui Jun Jeong, Hye Rim Lee
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This study examined whether big five personality traits affect game addiction with control of psychological, social, and demographic factors. Specifically, using data from a survey of 789 game users in Korea, we conducted a regression analysis to see the associations of psychological (loneliness/depression), social (activities with family/friends), self-efficacy (game/general), gaming (daily gaming time/perception), demographic (age/gender), and personality traits (extraversion, neuroticism conscientiousness, agreeableness, & openness) with the degree of game addiction. Results showed that neuroticism increase game addiction with no effect of extraversion on the addiction. General self-efficacy negatively affected game addiction, whereas game self-efficacy increased the degree of game addiction. Loneliness enhanced game addiction while depression showed a negative effect on the addiction. Results and implications are discussed.Keywords: Game addiction, big five personality, social activities, self-efficacy, loneliness, depression.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 4962302 Automatic Light Control in Domotics using Artificial Neural Networks
Authors: Carlos Machado, José A. Mendes
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Home Automation is a field that, among other subjects, is concerned with the comfort, security and energy requirements of private homes. The configuration of automatic functions in this type of houses is not always simple to its inhabitants requiring the initial setup and regular adjustments. In this work, the ubiquitous computing system vision is used, where the users- action patterns are captured, recorded and used to create the contextawareness that allows the self-configuration of the home automation system. The system will try to free the users from setup adjustments as the home tries to adapt to its inhabitants- real habits. In this paper it is described a completely automated process to determine the light state and act on them, taking in account the users- daily habits. Artificial Neural Network (ANN) is used as a pattern recognition method, classifying for each moment the light state. The work presented uses data from a real house where a family is actually living.Keywords: ANN, Home Automation, Neural Systems, PatternRecognition, Ubiquitous Computing.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2071301 Wildfires Assessed by Remote Sense Images and Burned Land Monitoring
Authors: M. C. Proença
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The tools described in this paper enable the location of burned areas where took place the annihilation of natural habitats and establishes a baseline for major changes in forest ecosystems during recovery. Moreover, the result allows the follow up of the surface fuel loading, allowing the evaluation and guidance of restoration measures to remote areas by phased time planning. This case study implements the evaluation of burned areas that suffered successive wildfires in Portugal mainland during the summer of 2017, killing more than 60 people. The goal is to show that this evaluation can be done with remote sense data free of charges in a simple laptop, with open-source software, describing the not-so-simple methodology step by step, to make it accessible for local workers in the areas attained, where the availability of information is essential for the immediate planning of mitigation measures, such as restoring road access, allocate funds for the recovery of human dwellings and assess further needs for restoration of the ecological system. Wildfires also devastate forest ecosystems having a direct impact on vegetation cover and killing or driving away the animal population, besides loss of all crops in rural areas that are essential as local resources. The economic interests are also attained, as the pinewood burned becomes useless for the noblest applications, so its value decreases, and resin extraction ends for several years.
Keywords: Image processing, remote sensing, wildfires, burned areas, SENTINEL-2.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1583300 Influence of Degradative Enzymatic Activities on the Shelf Life of Ready-to-Eat Prickly Pear Fruits
Authors: D. Scalone, R. Palmeri, F. Licciardello, G. Muratore, A. Todaro, G. Spagna
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Prickly pear fruit (Opuntia ficus indica L. Miller) belongs to the Cactaceae family. This species is very sensitive to low storage temperatures (< 5°C) which cause damages. The fruits can be peeled, suitably packaged and successfully commercialized as a ready-to-eat product. The main limit to the extension of the shelf life is the production of off-flavors due to different factors, the growth of microorganisms and the action of endogenous enzymes. Lipoxygenase (LOX) and Pectinesterase (PE) are involved in fruit degradation. In particular, LOX pathway is directly responsible for lipid oxidation, and the subsequent production of off-flavours, while PE causes the softening of fruit during maturation. They act on the texture and shelf-life of post-harvest, packaged fruits, as a function of the the grown of microorganisms and packaging technologies used. The aim of this work is to compare the effect of different packaging technologies on the shelf life extension of ready-to-eat prickly pear fruits with regards for the enzymes activities.
Keywords: Enzymes, packaging, prickly pear, shelf life.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1662299 Unstructured-Data Content Search Based on Optimized EEG Signal Processing and Multi-Objective Feature Extraction
Authors: Qais M. Yousef, Yasmeen A. Alshaer
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Over the last few years, the amount of data available on the globe has been increased rapidly. This came up with the emergence of recent concepts, such as the big data and the Internet of Things, which have furnished a suitable solution for the availability of data all over the world. However, managing this massive amount of data remains a challenge due to their large verity of types and distribution. Therefore, locating the required file particularly from the first trial turned to be a not easy task, due to the large similarities of names for different files distributed on the web. Consequently, the accuracy and speed of search have been negatively affected. This work presents a method using Electroencephalography signals to locate the files based on their contents. Giving the concept of natural mind waves processing, this work analyses the mind wave signals of different people, analyzing them and extracting their most appropriate features using multi-objective metaheuristic algorithm, and then classifying them using artificial neural network to distinguish among files with similar names. The aim of this work is to provide the ability to find the files based on their contents using human thoughts only. Implementing this approach and testing it on real people proved its ability to find the desired files accurately within noticeably shorter time and retrieve them as a first choice for the user.
Keywords: Artificial intelligence, data contents search, human active memory, mind wave, multi-objective optimization.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 920298 Optimal Current Control of Externally Excited Synchronous Machines in Automotive Traction Drive Applications
Authors: Oliver Haala, Bernhard Wagner, Maximilian Hofmann, Martin Marz
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The excellent suitability of the externally excited synchronous machine (EESM) in automotive traction drive applications is justified by its high efficiency over the whole operation range and the high availability of materials. Usually, maximum efficiency is obtained by modelling each single loss and minimizing the sum of all losses. As a result, the quality of the optimization highly depends on the precision of the model. Moreover, it requires accurate knowledge of the saturation dependent machine inductances. Therefore, the present contribution proposes a method to minimize the overall losses of a salient pole EESM and its inverter in steady state operation based on measurement data only. Since this method does not require any manufacturer data, it is well suited for an automated measurement data evaluation and inverter parametrization. The field oriented control (FOC) of an EESM provides three current components resp. three degrees of freedom (DOF). An analytic minimization of the copper losses in the stator and the rotor (assuming constant inductances) is performed and serves as a first approximation of how to choose the optimal current reference values. After a numeric offline minimization of the overall losses based on measurement data the results are compared to a control strategy that satisfies cos (ϕ) = 1.
Keywords: Current control, efficiency, externally excited synchronous machine, optimization.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 4395297 Role of Direct and Secondary Traumatic Experience on Later Functioning
Authors: Pamela L. Knox, Linda R. Guthrie
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Trauma in early life is widely regarded as a cause for adult mental health problems. This study explores the role of secondary trauma on later functioning in a sample of 359 university students enrolled in undergraduate psychology classes in the United States. Participants were initially divided into four groups based on 1) having directly experienced trauma (assaultive violence), 2) having directly experienced trauma and secondary traumatization through the unanticipated death of a close friend or family member or witnessing of an injury or shocking even), 3) having no experience of direct trauma but having experienced indirect trauma (secondary trauma), or 4) reporting no exposure. Participants completed a battery of measures on concepts associated with psychological functioning which included measures of psychological well-being, problem solving, coping and resiliency. Findings discuss differences in psychological functioning and resilience based on participants who experienced secondary traumatization and assaultive violence versus secondary traumatization alone.Keywords: Psychological Functioning, Resiliency, Trauma, Abuse
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2053296 Removal of Ni(II), Zn(II) and Pb(II) ions from Single Metal Aqueous Solution using Activated Carbon Prepared from Rice Husk
Authors: Mohd F. Taha, Chong F. Kiat, Maizatul S. Shaharun, Anita Ramli
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The abundance and availability of rice husk, an agricultural waste, make them as a good source for precursor of activated carbon. In this work, rice husk-based activated carbons were prepared via base treated chemical activation process prior the carbonization process. The effect of carbonization temperatures (400, 600 and 800oC) on their pore structure was evaluated through morphology analysis using scanning electron microscope (SEM). Sample carbonized at 800oC showed better evolution and development of pores as compared to those carbonized at 400 and 600oC. The potential of rice husk-based activated carbon as an alternative adsorbent was investigated for the removal of Ni(II), Zn(II) and Pb(II) from single metal aqueous solution. The adsorption studies using rice husk-based activated carbon as an adsorbent were carried out as a function of contact time at room temperature and the metal ions were analyzed using atomic absorption spectrophotometer (AAS). The ability to remove metal ion from single metal aqueous solution was found to be improved with the increasing of carbonization temperature. Among the three metal ions tested, Pb(II) ion gave the highest adsorption on rice husk-based activated carbon. The results obtained indicate the potential to utilize rice husk as a promising precursor for the preparation of activated carbon for removal of heavy metals.
Keywords: Activated carbon, metal ion adsorption, rice husk, wastewater treatment.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2717295 A Cross-Disciplinary Educational Model in Biomanufacturing to Sustain a Competitive Workforce Ecosystem
Authors: Rosa Buxeda, Lorenzo Saliceti-Piazza, Rodolfo J. Romañach, Luis Ríos, Sandra L. Maldonado-Ramírez
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Biopharmaceuticals manufacturing is one of the major economic activities worldwide. Ninety-three percent of the workforce in a biomanufacturing environment concentrates in production-related areas. As a result, strategic collaborations between industry and academia are crucial to ensure the availability of knowledgeable workforce needed in an economic region to become competitive in biomanufacturing. In the past decade, our institution has been a key strategic partner with multinational biotechnology companies in supplying science and engineering graduates in the field of industrial biotechnology. Initiatives addressing all levels of the educational pipeline, from K-12 to college to continued education for company employees have been established along a ten-year span. The Amgen BioTalents Program was designed to provide undergraduate science and engineering students with training in biomanufacturing. The areas targeted by this educational program enhance their academic development, since these topics are not part of their traditional science and engineering curricula. The educational curriculum involved the process of producing a biomolecule from the genetic engineering of cells to the production of an especially targeted polypeptide, protein expression and purification, to quality control, and validation. This paper will report and describe the implementation details and outcomes of the first sessions of the program.
Keywords: Biomanufacturing curriculum, interdisciplinary learning, workforce development, industry-academia partnering.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1975294 AI-Based Approaches for Task Offloading, Resource Allocation and Service Placement of IoT Applications: State of the Art
Authors: Fatima Z. Cherhabil, Mammar Sedrati, Sonia-Sabrina Bendib
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In order to support the continued growth, critical latency of IoT applications and various obstacles of traditional data centers, Mobile Edge Computing (MEC) has emerged as a promising solution that extends the cloud data-processing and decision-making to edge devices. By adopting a MEC structure, IoT applications could be executed locally, on an edge server, different fog nodes or distant cloud data centers. However, we are often faced with wanting to optimize conflicting criteria such as minimizing energy consumption of limited local capabilities (in terms of CPU, RAM, storage, bandwidth) of mobile edge devices and trying to keep high performance (reducing response time, increasing throughput and service availability) at the same time. Achieving one goal may affect the other making Task Offloading (TO), Resource Allocation (RA) and Service Placement (SP) complex processes. It is a nontrivial multi-objective optimization problem to study the trade-off between conflicting criteria. The paper provides a survey on different TO, SP and RA recent Multi-Objective Optimization (MOO) approaches used in edge computing environments, particularly Artificial Intelligent (AI) ones, to satisfy various objectives, constraints and dynamic conditions related to IoT applications.
Keywords: Mobile Edge Computing, Multi-Objective Optimization, Artificial Intelligence Approaches, Task Offloading, Resource Allocation, Service Placement.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 514293 Parallel Branch and Bound Model Using Logarithmic Sampling (PBLS) for Symmetric Traveling Salesman Problem
Authors: Sheikh Muhammad Azam, Masood-ur-Rehman, Adnan Khalid Bhatti, Nadeem Daudpota
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Very Large and/or computationally complex optimization problems sometimes require parallel or highperformance computing for achieving a reasonable time for computation. One of the most popular and most complicate problems of this family is “Traveling Salesman Problem". In this paper we have introduced a Branch & Bound based algorithm for the solution of such complicated problems. The main focus of the algorithm is to solve the “symmetric traveling salesman problem". We reviewed some of already available algorithms and felt that there is need of new algorithm which should give optimal solution or near to the optimal solution. On the basis of the use of logarithmic sampling, it was found that the proposed algorithm produced a relatively optimal solution for the problem and results excellent performance as compared with the traditional algorithms of this series.
Keywords: Parallel execution, symmetric traveling salesman problem, branch and bound algorithm, logarithmic sampling.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2337292 Architecture for Smart Cities’ Sustainable Modular Houses
Authors: Khaled Elbehiery, Hussam Elbehiery
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Smart cities are a framework of technologies along with sustainable infrastructure to provide their citizens an improved quality of life, safer environment, affordability, and more, which in turn helps with the society's economic growth. The proposed research will focus on the primary building block of the smart city; the infrastructure of the house itself. The traditional method of building houses has been, for a long time, nothing but a costly manufacturing process, and consequently, buying a house becomes not an option for everyone anymore. The smart cities' Modular Houses are not using traditional building construction materials; the design reduces the common lengthy construction times and associated high costs. The Modular Houses are technological homes, low-cost and customizable based on a family's requirements. In addition, the Modular Houses are environmentally friendly and healthy enough to assist with the pandemic situation.
Keywords: Smart cities, modular houses, single-unit property, multi-unit property, mobility features, chain-supply, livable environment, carbon footprint.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 318291 Identification of Aquatic and Semi aquatic Birds of Sattarkhan Lake (East Azerbaijan- Iran)
Authors: Mahbobeh Hajirostamloo
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Aquatic and semi aquatic birds as a group are suited to feed and breed in environments in which water forms a fundamental part. These birds are biological indicator in aquatic environment, because these birds belong to the top level of food chain in aquatic ecosystems. There are 61 species in 14 families of aquatic and semi aquatic birds in Iran. The birds of the Sattarkhan Lake belong to 16 species in 8 families which include 26.2 percent of total Aquatic and semi aquatic bird species and 57% of Aquatic and semi aquatic bird's family of Iran. Study was carried out monthly at Sattarkhan Lake show the existence of Phalacrocorax carbo, Ardea cinerea, Egretta alba, Egretta garzetta, Bubulcus ibis, Botaurus stellaris, Sterna hirundo, Chlidonias leucopterus, Larus minutus, Larus argentatus, Larus ridibunbus, Alcedo atthis, Ciconia ciconia, Plegadis falcinellus, Circus aeruginosus, Corvus frugilegusKeywords: Aquatic bird, Sattarkhan Lake, Identification, Iran
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1730290 Data-Reusing Adaptive Filtering Algorithms with Adaptive Error Constraint
Authors: Young-Seok Choi
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We present a family of data-reusing and affine projection algorithms. For identification of a noisy linear finite impulse response channel, a partial knowledge of a channel, especially noise, can be used to improve the performance of the adaptive filter. Motivated by this fact, the proposed scheme incorporates an estimate of a knowledge of noise. A constraint, called the adaptive noise constraint, estimates an unknown information of noise. By imposing this constraint on a cost function of data-reusing and affine projection algorithms, a cost function based on the adaptive noise constraint and Lagrange multiplier is defined. Minimizing the new cost function leads to the adaptive noise constrained (ANC) data-reusing and affine projection algorithms. Experimental results comparing the proposed schemes to standard data-reusing and affine projection algorithms clearly indicate their superior performance.Keywords: Data-reusing, affine projection algorithm, error constraint, system identification.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1619289 Biotechonomy System Dynamics Modelling: Sustainability of Pellet Production
Authors: Andra Blumberga, Armands Gravelsins, Haralds Vigants, Dagnija Blumberga
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The paper discovers biotechonomy development analysis by use of system dynamics modelling. The research is connected with investigations of biomass application for production of bioproducts with higher added value. The most popular bioresource is wood, and therefore, the main question today is about future development and eco-design of products. The paper emphasizes and evaluates energy sector which is open for use of wood logs, wood chips, wood pellets and so on. The main aim for this research study was to build a framework to analyse development perspectives for wood pellet production. To reach the goal, a system dynamics model of energy wood supplies, processing, and consumption is built. Production capacity, energy consumption, changes in energy and technology efficiency, required labour source, prices of wood, energy and labour are taken into account. Validation and verification tests with available data and information have been carried out and indicate that the model constitutes the dynamic hypothesis. It is found that the more is invested into pellets production, the higher the specific profit per production unit compared to wood logs and wood chips. As a result, wood chips production is decreasing dramatically and is replaced by wood pellets. The limiting factor for pellet industry growth is availability of wood sources. This is governed by felling limit set by the government based on sustainable forestry principles.
Keywords: Bioenergy, biotechonomy, system dynamics modelling, wood pellets.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1170288 An Exploration of the Provision of Government-Subsidised Housing without Title Deeds: A Recipient’s Interpretation of Security of Tenure
Authors: Maléne Maria Magdalena Campbell, Jeremiah Mholo
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Low-income households earning less than 3,500 ZAR (about 175 GBP) per month can apply to the South African government, through the National Housing Subsidy, for fully subsidised houses. An objective of this subsidy is to enable low-income households’ participation in the formal housing market; however, the beneficiaries received houses without title deeds. As such, if the beneficiaries did not have a secured tenure at the time of their death then surviving family may face possible eviction. Therefore, an aim of this research was to determine how these beneficiaries interpret tenure security. The research focused on government subsidised housing in the Dithlake settlement of a rural hamlet named Koffiefontein, in the Letsemeng Local Municipality of South Africa. Quantitative data on the beneficiaries were collected from the local municipality, while qualitative data were collected from a sample of 45 beneficiaries.Keywords: Low-income families, subsidised housing, titling, housing market, South Africa.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1369287 The Relationship between Students- Socio-Economic Backgrounds and Student Residential Satisfaction
Authors: Nurul ‘Ulyani Mohd Najib, Nor’ Aini Yusof, Zulkifli Osman
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Debates on residential satisfaction topic have been vigorously discussed in family house setting. Nonetheless, less or lack of attention was given to survey on student residential satisfaction in the campus house setting. This study, however, tried to fill in the gap by focusing more on the relationship between students- socio-economic backgrounds and student residential satisfaction with their on-campus student housing facilities. Two-stage cluster sampling method was employed to classify the respondents. Then, self-administered questionnaires were distributed face-to-face to the students. In general, it was confirmed that the students- socioeconomic backgrounds have significantly influence the students- satisfaction with their on-campus student housing facilities. The main influential factors were revealed as the economic status, sense of sharing, and the ethnicity of roommates. Likewise, this study could also provide some useful feedback for the universities administration in order to improve their student housing facilities.Keywords: Malaysia, Socio-economic, Student housing, Studentresidential satisfaction
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2003286 Graves’ Disease and Its Related Single Nucleotide Polymorphisms and Genes
Authors: Yuhong Lu
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Graves’ Disease (GD), an autoimmune health condition caused by the over reactiveness of the thyroid, affects about 1 in 200 people worldwide. GD is not caused by one specific single nucleotide polymorphism (SNP) or gene mutation, but rather determined by multiple factors, each differing from each other. Malfunction of the genes in Human Leukocyte Antigen (HLA) family tend to play a major role in autoimmune diseases, but other genes, such as LOC101929163, have functions that still remain ambiguous. Currently, little studies were done to study GD, resulting in inconclusive results. This study serves not only to introduce background knowledge about GD, but also to organize and pinpoint the major SNPs and genes that are potentially related to the occurrence of GD in humans. Collected from multiple sources from genome-wide association studies (GWAS) Central, the potential SNPs related to the causes of GD are included in this study. This study has located the genes that are related to those SNPs and closely examines a selected sample. Using the data from this study, scientists will then be able to focus on the most expressed genes in GD patients and develop a treatment for GD.
Keywords: CTLA4, Graves’ Disease, HLA, single nucleotide polymorphism, SNP.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 578285 Ficus deltoidea Extract Protects HaCaT Keratinocytes from UVB Irradiation-Induced Inflammation
Authors: Rosnani Hasham, Hyun Kyung Choi, Chang Seo Park
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Ficus deltoidea from the Moraceae family is a popular medicinal herb in Malaysia. It possesses strong antioxidant and antiinflammatory properties. In the present study, the anti-inflammatory effects of F. deltoidea extract on UVB-irradiated HaCaT Keratinocytes were investigated. HaCaT Keratinocytes were UVBirradiated (12.5 mJ/cm3) and were treated with 0.05, 0.08 or 0.1% of F. deltoidea extract. Cell viability following UVB irradiation was significantly higher in the groups treated with the F. deltoidea extract at doses of 0.05, 0.08 or 0.1% than in control group with UVB irradiation only. Tumor necrosis factor-α (TNF-α), interleukin-1α (IL-1α), interleukin-6 (IL-6) and cyclooxygenase (COX-2) play primary roles in the inflammation process upon UV irradiation and are known to be stimulated by UVB irradiation. Treatment with the F. deltoidea extract dramatically inhibited the UV-induced TNF-α, IL-1α, IL-6, and COX-2 expression. These results suggest that the F. deltoidea extract inhibits the production of pro-inflammatory cytokines and may be an effective protective agent for the treatment of skin diseases.
Keywords: Ficus deltoidea, anti-inflammatory activity, cytokines, COX-2.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2836284 Quality of Life: Expectations and Achievements of Middle Class in Kazakhstan
Authors: Nazym Shedenova, Aigul Beimisheva
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The improvement of quality of life is the main visible integrated indicator of state well-being. More and more states pay attention to define and to achieve social standards of quality of life as social-economic strategy of development. These standards are determinate by state features, complex of needs and interests of individual, family and society. It still remains in open question: “What is middle class" in contemporary Kazakhstan. Appearance of new social standards of quality of life is important indicator of its successful establishment. The middle class as agent of social, politic and economic reforms promotes to improve the quality of life of the country. But if consider a low and a middle stratums of middle class, we can see that high social expectations and real achievements are still significantly different. The article relies on the sociological data, collected during of search of household-s standards of living in Almaty city and Almaty region, and case-study of cottage city “Jana Kuat".Keywords: the quality of life, the social standards of life, the middle class of Kazakhstan, the economic behavior of households.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2735283 Histopathological Alterations in Liver of Mice Exposed to Different Doses of Diclofenac Sodium
Authors: Deepak Mohan, Sushma Sharma
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Diclofenac sodium, a member of the acetic acid family of non-steroidal anti-inflammatory drugs, is used to retard inflammation, arthritis pain and ankylosing spondylitis. The drug is known to cause severe injury in different tissues due to formation of reactive oxygen species. The present study is focused on the effect of different doses of diclofenac (4 mg/kg/body weight and 14 mg/kg/body weight on histoarchitecture of the liver from 7-28 days of the investigation. Diclofenac administration resulted in distorted hepatic degeneration and formation of wide areas in the form of sinusoidal gaps. Hepatic fibrosis noticed in different stages of investigation could be attributed to chronic inflammation and reactive oxygen species which results in deposition of extracellular matrix proteins. The abrupt degenerative changes observed during later stages of the experiment showed maximum damage to the liver, and there was enlargement of sinusoidal gaps accompanied by maximum necrosis in the tissues.
Keywords: Arthritis, diclofenac, histoarchitecture, sinusoidal.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1162282 Material Failure Process Simulation by Improve Finite Elements with Embedded Discontinuities
Authors: Juárez-Luna Gelacio, Ayala Gustavo, Retama-Velasco Jaime
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This paper shows the advantages of the material failure process simulation by improve finite elements with embedded discontinuities, using a new definition of traction vector, dependent on the discontinuity length and the angle. Particularly, two families of this kind of elements are compared: kinematically optimal symmetric and statically and kinematically optimal non-symmetric. The constitutive model to describe the behavior of the material in the symmetric formulation is a traction-displacement jump relationship equipped with softening after reaching the failure surface.
To show the validity of this symmetric formulation, representative numerical examples illustrating the performance of the proposed formulation are presented. It is shown that the non-symmetric family may over or underestimate the energy required to create a discontinuity, as this effect is related with the total length of the discontinuity, fact that is not noticed when the discontinuity path is a straight line.
Keywords: Variational formulation, strong discontinuity, embedded discontinuities, strain localization.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1770281 Callusing in Stevia rebaudiana (Natural Sweetener) for Steviol Glycoside Production
Authors: Pratibha Gupta, Satyawati Sharma, Sanjay Saxena
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Stevia rebaudiana Bertoni (natural sweetener) belongs to Asteraceae family and can be used as substitute of artificial sweeteners for diabetic patients. Conventionally, it is cultivated by seeds or stem cutting, but seed viability rate is poor. A protocol for callus induction and multiplication was developed to produce large no. of calli in short period. Surface sterilized nodal, leaf and root explants were cultured on Murashige and Skoog (MS) medium with different concentrations of plant hormone like, IBA, kinetin, NAA, 2,4-D, and NAA in combination with 2,4-D. 100% callusing was observed from leaf explants cultured on combination of NAA and 2,4-D after three weeks while with 2,4-D, only 10% callusing was observed. Calli obtained from leaf and root explants were shiny green while with nodal explants it was hard and brown. The present findings deal with induction of callusing in Stevia to achieve the rapid callus multiplication for study of steviol glycosides in callus culture.Keywords: 2, 4-D, Callusing, NAA, Stevia, Steviol glycosides
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3258280 The Challenges and Solutions for Developing Mobile Apps in a Small University
Authors: Greg Turner, Bin Lu, Cheer-Sun Yang
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As computing technology advances, smartphone applications can assist student learning in a pervasive way. For example, the idea of using mobile apps for the PA Common Trees, Pests, Pathogens, in the field as a reference tool allows middle school students to learn about trees and associated pests/pathogens without bringing a textbook. While working on the development of three heterogeneous mobile apps, we ran into numerous challenges. Both the traditional waterfall model and the more modern agile methodologies failed in practice. The waterfall model emphasizes the planning of the duration for each phase. When the duration of each phase is not consistent with the availability of developers, the waterfall model cannot be employed. When applying Agile Methodologies, we cannot maintain the high frequency of the iterative development review process, known as ‘sprints’. In this paper, we discuss the challenges and solutions. We propose a hybrid model known as the Relay Race Methodology to reflect the concept of racing and relaying during the process of software development in practice. Based on the development project, we observe that the modeling of the relay race transition between any two phases is manifested naturally. Thus, we claim that the RRM model can provide a de fecto rather than a de jure basis for the core concept in the software development model. In this paper, the background of the project is introduced first. Then, the challenges are pointed out followed by our solutions. Finally, the experiences learned and the future works are presented.Keywords: Agile methods, mobile apps, software process model, waterfall model.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1603279 An Experimental Investigation of Thermoelectric Air-Cooling Module
Authors: Yu-Wei Chang, Chiao-Hung Cheng, Wen-Fang Wu, Sih-Li Chen
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This article experimentally investigates the thermal performance of thermoelectric air-cooling module which comprises a thermoelectric cooler (TEC) and an air-cooling heat sink. The influences of input current and heat load are determined. And performances under each situation are quantified by thermal resistance analysis. Since TEC generates Joule heat, this nature makes construction of thermal resistance network difficult. To simplify the analysis, this article emphasizes on the resistance heat load might meet when passing through the device. Therefore, the thermal resistances in this paper are to divide temperature differences by heat load. According to the result, there exists an optimum input current under every heating power. In this case, the optimum input current is around 6A or 7A. The performance of the heat sink would be improved with TEC under certain heating power and input current, especially at a low heat load. According to the result, the device can even make the heat source cooler than the ambient. However, TEC is not always effective at every heat load and input current. In some situation, the device works worse than the heat sink without TEC. To determine the availability of TEC, this study figures out the effective operating region in which the TEC air-cooling module works better than the heat sink without TEC. The result shows that TEC is more effective at a lower heat load. If heat load is too high, heat sink with TEC will perform worse than without TEC. The limit of this device is 57W. Besides, TEC is not helpful if input current is too high or too low. There is an effective range of input current, and the range becomes narrower when the heat load grows.Keywords: Thermoelectric cooler, TEC, electronic cooling, heat sink.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3711278 Towards External Varieties to Internal Varieties − Modular Perspective
Authors: AHM Shamsuzzoha, Tauno Kekäle, Petri Helo
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Product customization is an essential requirement for manufacturing firms to achieve higher customers- satisfaction and fulfill business target. In order to achieve these objectives, firms need to handle both external varieties such as customer preference, government regulations, cultural considerations etc and internal varieties such as functional requirements of product, production efficiency, quality etc. Both of the varieties need to be accumulated and integrated together for the purpose of producing customized product. These varieties are presented and discussed in this paper along with the perspectives of modular product design and development process. Other development strategies such as modularity, component commonality, product family design and product platform are presented with a view to achieve product variety quickly and economically. A case example both for the concept of modular design and platform based product development process is also presented with the help of design structure matrix (DSM) tool. This paper is concluded with several managerial implications and future research direction.Keywords: Customization modular design, platform development, product variety.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1462277 Aircraft Supplier Selection Process with Fuzzy Proximity Measure Method using Multiple Criteria Group Decision Making Analysis
Authors: C. Ardil
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Being effective in every organizational activity has become necessary due to the escalating level of competition in all areas of corporate life. In the context of supply chain management, aircraft supplier selection is currently one of the most crucial activities. It is possible to choose the best aircraft supplier and deliver efficiency in terms of cost, quality, delivery time, economic status, and institutionalization if a systematic supplier selection approach is used. In this study, an effective multiple criteria decision-making methodology, proximity measure method (PMM), is used within a fuzzy environment based on the vague structure of the real working environment. The best appropriate aircraft suppliers are identified and ranked after the proposed multiple criteria decision making technique is used in a real-life scenario.
Keywords: Aircraft supplier selection, multiple criteria decision making, fuzzy sets, proximity measure method, Minkowski distance family function, Hausdorff distance function, PMM, MCDM
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 343