Search results for: CELP residual coding
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 536

Search results for: CELP residual coding

266 Earthquake Analysis of Reinforce Concrete Framed Structures with Added Viscous Dampers

Authors: F. Hejazi, J. Noorzaei, M. S. Jaafar, A. A. Abang Abdullah

Abstract:

This paper describes the development of a numerical finite element algorithm used for the analysis of reinforced concrete structure equipped with shakes energy absorbing device subjected to earthquake excitation. For this purpose a finite element program code for analysis of reinforced concrete frame buildings is developed. The performance of developed program code is evaluated by analyzing of a reinforced concrete frame buildings model. The results are show that using damper device as seismic energy dissipation system effectively can reduce the structural response of framed structure during earthquake occurrence.

Keywords: Viscous Damper, finite element, program coding

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265 Size-Reduction Strategies for Iris Codes

Authors: Jutta Hämmerle-Uhl, Georg Penn, Gerhard Pötzelsberger, Andreas Uhl

Abstract:

Iris codes contain bits with different entropy. This work investigates different strategies to reduce the size of iris code templates with the aim of reducing storage requirements and computational demand in the matching process. Besides simple subsampling schemes, also a binary multi-resolution representation as used in the JBIG hierarchical coding mode is assessed. We find that iris code template size can be reduced significantly while maintaining recognition accuracy. Besides, we propose a two-stage identification approach, using small-sized iris code templates in a pre-selection stage, and full resolution templates for final identification, which shows promising recognition behaviour.

Keywords: Iris recognition, compact iris code, fast matching, best bits, pre-selection identification, two-stage identification.

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264 Prediction of MicroRNA-Target Gene by Machine Learning Algorithms in Lung Cancer Study

Authors: Nilubon Kurubanjerdjit, Nattakarn Iam-On, Ka-Lok Ng

Abstract:

MicroRNAs are small non-coding RNA found in many different species. They play crucial roles in cancer such as biological processes of apoptosis and proliferation. The identification of microRNA-target genes can be an essential first step towards to reveal the role of microRNA in various cancer types. In this paper, we predict miRNA-target genes for lung cancer by integrating prediction scores from miRanda and PITA algorithms used as a feature vector of miRNA-target interaction. Then, machine-learning algorithms were implemented for making a final prediction. The approach developed in this study should be of value for future studies into understanding the role of miRNAs in molecular mechanisms enabling lung cancer formation.

Keywords: MicroRNA, miRNAs, lung cancer, machine learning, Naïve Bayes, SVM.

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263 Channel Sounding and PAPR Reduction in OFDM for WiMAX Using Software Defined Radio

Authors: B. Siva Kumar Reddy, B. Lakshmi

Abstract:

This paper addresses the reduction of peak to average power ratio (PAPR) for the OFDM in Mobile-WiMAX physical layer (PHY) standard. In the process, the best achievable PAPR of 0 dB is found for the OFDM spectrum using phase modulation technique which avoids the nonlinear distortion. The performance of the WiMAX PHY standard is handled by the software defined radio (SDR) prototype in which GNU Radio and USRP N210 employed as software and hardware platforms respectively. It is also found that BER performance is shown for different coding and different modulation schemes. To empathize wireless propagation in specific environments, a sliding correlator wireless channel sounding system is designed by using SDR testbed.

Keywords: BER, Channel sounding, GNU Radio, OFDM/OFDMA, USRP N210.

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262 A Perceptual Image Coding method of High Compression Rate

Authors: Fahmi Kammoun, Mohamed Salim Bouhlel

Abstract:

In the framework of the image compression by Wavelet Transforms, we propose a perceptual method by incorporating Human Visual System (HVS) characteristics in the quantization stage. Indeed, human eyes haven-t an equal sensitivity across the frequency bandwidth. Therefore, the clarity of the reconstructed images can be improved by weighting the quantization according to the Contrast Sensitivity Function (CSF). The visual artifact at low bit rate is minimized. To evaluate our method, we use the Peak Signal to Noise Ratio (PSNR) and a new evaluating criteria witch takes into account visual criteria. The experimental results illustrate that our technique shows improvement on image quality at the same compression ratio.

Keywords: Contrast Sensitivity Function, Human Visual System, Image compression, Wavelet transforms.

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261 Bangla Vowel Characterization Based on Analysis by Synthesis

Authors: Syed Akhter Hossain, M. Lutfar Rahman, Farruk Ahmed

Abstract:

Bangla Vowel characterization determines the spectral properties of Bangla vowels for efficient synthesis as well as recognition of Bangla vowels. In this paper, Bangla vowels in isolated word have been analyzed based on speech production model within the framework of Analysis-by-Synthesis. This has led to the extraction of spectral parameters for the production model in order to produce different Bangla vowel sounds. The real and synthetic spectra are compared and a weighted square error has been computed along with the error in the formant bandwidths for efficient representation of Bangla vowels. The extracted features produced good representation of targeted Bangla vowel. Such a representation also plays essential role in low bit rate speech coding and vocoders.

Keywords: Speech, vowel, formant, synthesis, spectrum, LPC.

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260 Entanglement-based Quantum Computing by Diagrams of States

Authors: Sara Felloni, Giuliano Strini

Abstract:

We explore entanglement in composite quantum systems and how its peculiar properties are exploited in quantum information and communication protocols by means of Diagrams of States, a novel method to graphically represent and analyze how quantum information is elaborated during computations performed by quantum circuits. We present quantum diagrams of states for Bell states generation, measurements and projections, for dense coding and quantum teleportation, for probabilistic quantum machines designed to perform approximate quantum cloning and universal NOT and, finally, for quantum privacy amplification based on entanglement purification. Diagrams of states prove to be a useful approach to analyze quantum computations, by offering an intuitive graphic representation of the processing of quantum information. They also help in conceiving novel quantum computations, from describing the desired information processing to deriving the final implementation by quantum gate arrays.

Keywords: Diagrams of states, entanglement, quantum circuits, quantum information.

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259 Watermark Bit Rate in Diverse Signal Domains

Authors: Nedeljko Cvejic, Tapio Sepp

Abstract:

A study of the obtainable watermark data rate for information hiding algorithms is presented in this paper. As the perceptual entropy for wideband monophonic audio signals is in the range of four to five bits per sample, a significant amount of additional information can be inserted into signal without causing any perceptual distortion. Experimental results showed that transform domain watermark embedding outperforms considerably watermark embedding in time domain and that signal decompositions with a high gain of transform coding, like the wavelet transform, are the most suitable for high data rate information hiding. Keywords?Digital watermarking, information hiding, audio watermarking, watermark data rate.

Keywords: Digital watermarking, information hiding, audio watermarking, watermark data rate.

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258 Real-Time Control of a Two-Wheeled Inverted Pendulum Mobile Robot

Authors: S. W. Nawawi, M. N. Ahmad, J. H. S. Osman

Abstract:

The research on two-wheeled inverted pendulum (TWIP) mobile robots or commonly known as balancing robots have gained momentum over the last decade in a number of robotic laboratories around the world. This paper describes the hardware design of such a robot. The objective of the design is to develop a TWIP mobile robot as well as MATLAB interfacing configuration to be used as flexible platform comprises of embedded unstable linear plant intended for research and teaching purposes. Issues such as selection of actuators and sensors, signal processing units, MATLAB Real Time Workshop coding, modeling and control scheme will be addressed and discussed. The system is then tested using a wellknown state feedback controller to verify its functionality.

Keywords: Embedded System, Two-wheeled Inverted Pendulum Mobile Robot.

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257 OILU Tag: A Projective Invariant Fiducial System

Authors: Youssef Chahir, Messaoud Mostefai, Salah Khodja

Abstract:

This paper presents the development of a 2D visual marker, derived from a recent patented work in the field of numbering systems. The proposed fiducial uses a group of projective invariant straight-line patterns, easily detectable and remotely recognizable. Based on an efficient data coding scheme, the developed marker enables producing a large panel of unique real time identifiers with highly distinguishable patterns. The proposed marker Incorporates simultaneously decimal and binary information, making it readable by both humans and machines. This important feature opens up new opportunities for the development of efficient visual human-machine communication and monitoring protocols. Extensive experiment tests validate the robustness of the marker against acquisition and geometric distortions.

Keywords: visual marker, projective invariants, distance map, level set

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256 Removal of Iron from Groundwater by Sulfide Precipitation

Authors: H. Jusoh, N. Sapari, R.Z. Raja Azie

Abstract:

Iron in groundwater is one of the problems that render the water unsuitable for drinking. The concentration above 0.3 mg/L is common in groundwater. The conventional method of removal is by precipitation under oxic condition. In this study, iron removal under anaerobic conditions was examined by batch experiment as a main purpose. The process involved by purging of groundwater samples with H2S to form iron sulfide. Removal up to 83% for 1 mg/L iron solution was achieved. The removal efficiency dropped to 82% and 75% for the higher initial iron concentrations 3.55 and 5.01 mg/L, respectively. The average residual sulfide concentration in water after the process was 25*g/L. The Eh level during the process was -272 mV. The removal process was found to follow the first order reaction with average rate constant of 4.52 x 10-3. The half-life for the concentrations to reduce from initial values was 157 minutes.

Keywords: Anaerobic, chemical kinetics, hydrogen sulfide, iron, rate constant

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255 Dynamic Data Partition Algorithm for a Parallel H.264 Encoder

Authors: Juntae Kim, Jaeyoung Park, Kyoungkun Lee, Jong Tae Kim

Abstract:

The H.264/AVC standard is a highly efficient video codec providing high-quality videos at low bit-rates. As employing advanced techniques, the computational complexity has been increased. The complexity brings about the major problem in the implementation of a real-time encoder and decoder. Parallelism is the one of approaches which can be implemented by multi-core system. We analyze macroblock-level parallelism which ensures the same bit rate with high concurrency of processors. In order to reduce the encoding time, dynamic data partition based on macroblock region is proposed. The data partition has the advantages in load balancing and data communication overhead. Using the data partition, the encoder obtains more than 3.59x speed-up on a four-processor system. This work can be applied to other multimedia processing applications.

Keywords: H.264/AVC, video coding, thread-level parallelism, OpenMP, multimedia

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254 New VLSI Architecture for Motion Estimation Algorithm

Authors: V. S. K. Reddy, S. Sengupta, Y. M. Latha

Abstract:

This paper presents an efficient VLSI architecture design to achieve real time video processing using Full-Search Block Matching (FSBM) algorithm. The design employs parallel bank architecture with minimum latency, maximum throughput, and full hardware utilization. We use nine parallel processors in our architecture and each controlled by a state machine. State machine control implementation makes the design very simple and cost effective. The design is implemented using VHDL and the programming techniques we incorporated makes the design completely programmable in the sense that the search ranges and the block sizes can be varied to suit any given requirements. The design can operate at frequencies up to 36 MHz and it can function in QCIF and CIF video resolution at 1.46 MHz and 5.86 MHz, respectively.

Keywords: Video Coding, Motion Estimation, Full-Search, Block-Matching, VLSI Architecture.

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253 Landscape Data Transformation: Categorical Descriptions to Numerical Descriptors

Authors: Dennis A. Apuan

Abstract:

Categorical data based on description of the agricultural landscape imposed some mathematical and analytical limitations. This problem however can be overcome by data transformation through coding scheme and the use of non-parametric multivariate approach. The present study describes data transformation from qualitative to numerical descriptors. In a collection of 103 random soil samples over a 60 hectare field, categorical data were obtained from the following variables: levels of nitrogen, phosphorus, potassium, pH, hue, chroma, value and data on topography, vegetation type, and the presence of rocks. Categorical data were coded, and Spearman-s rho correlation was then calculated using PAST software ver. 1.78 in which Principal Component Analysis was based. Results revealed successful data transformation, generating 1030 quantitative descriptors. Visualization based on the new set of descriptors showed clear differences among sites, and amount of variation was successfully measured. Possible applications of data transformation are discussed.

Keywords: data transformation, numerical descriptors, principalcomponent analysis

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252 Performance Analysis of M-Ary Pulse Position Modulation in Multihop Multiple Input Multiple Output-Free Space Optical System over Uncorrelated Gamma-Gamma Atmospheric Turbulence Channels

Authors: Hechmi Saidi, Noureddine Hamdi

Abstract:

The performance of Decode and Forward (DF) multihop Free Space Optical ( FSO) scheme deploying Multiple Input Multiple Output (MIMO) configuration under Gamma-Gamma (GG) statistical distribution, that adopts M-ary Pulse Position Modulation (MPPM) coding, is investigated. We have extracted exact and estimated values of Symbol-Error Rates (SERs) respectively. A closed form formula related to the Probability Density Function (PDF) is expressed for our designed system. Thanks to the use of DF multihop MIMO FSO configuration and MPPM signaling, atmospheric turbulence is combatted; hence the transmitted signal quality is improved.

Keywords: FSO, MIMO, MIMO, multihop, DF, SER, GG channel.

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251 Analysis of Normal Penetration of Ogive -Nose Projectiles into Thin Metallic Plates

Authors: M. H. Pol, A. Bidi, A.V. Hoseini, G.H. Liaghat

Abstract:

In this note, a theoretical model for analyzing of normal penetration of the ogive – nose projectile into metallic targets is presented .The failure is assumed to be asymmetry petalling and the analysis is performed by using the energy balance and work done .The work done consist of the work required for plastic deformation Wp, the work for transferring the matter to new position Wd and the work for bending of the petals Wb. In several studies, it has been shown that we can neglect the loss of energy by temperature. In this present study, in first, by assuming the crater formation after perforation, the value of work done is calculated during the normal penetration of conical projectiles into thin metallic targets. Then the value of residual velocity and ballistic limit of the projectile is predicated by using the energy balance. In final, theoretical and experimental results is compared.

Keywords: Ogive Projectile, normal impact, penetration, thinmetallic target.

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250 Extended Constraint Mask Based One-Bit Transform for Low-Complexity Fast Motion Estimation

Authors: Oğuzhan Urhan

Abstract:

In this paper, an improved motion estimation (ME) approach based on weighted constrained one-bit transform is proposed for block-based ME employed in video encoders. Binary ME approaches utilize low bit-depth representation of the original image frames with a Boolean exclusive-OR based hardware efficient matching criterion to decrease computational burden of the ME stage. Weighted constrained one-bit transform (WC‑1BT) based approach improves the performance of conventional C-1BT based ME employing 2-bit depth constraint mask instead of a 1-bit depth mask. In this work, the range of constraint mask is further extended to increase ME performance of WC-1BT approach. Experiments reveal that the proposed method provides better ME accuracy compared existing similar ME methods in the literature.

Keywords: Fast motion estimation, low-complexity motion estimation, video coding.

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249 Direct Design of Steel Bridge Using Nonlinear Inelastic Analysis

Authors: Boo-Sung Koh, Seung-Eock Kim

Abstract:

In this paper, a direct design using a nonlinear inelastic analysis is suggested. Also, this paper compares the load carrying capacity obtained by a nonlinear inelastic analysis with experiment results to verify the accuracy of the results. The allowable stress design results of a railroad through a plate girder bridge and the safety factor of the nonlinear inelastic analysis were compared to examine the safety performance. As a result, the load safety factor for the nonlinear inelastic analysis was twice as high as the required safety factor under the allowable stress design standard specified in the civil engineering structure design standards for urban magnetic levitation railways, which further verified the advantages of the proposed direct design method.

Keywords: Direct design, nonlinear inelastic analysis, residual stress, initial geometric imperfection.

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248 Space Time Processing with Adaptive STBC-OFDM Systems

Authors: F. Sarabchi, M. E. Kalantari

Abstract:

In this paper, Optimum adaptive loading algorithms are applied to multicarrier system with Space-Time Block Coding (STBC) scheme associated with space-time processing based on singular-value decomposition (SVD) of the channel matrix over Rayleigh fading channels. SVD method has been employed in MIMO-OFDM system in order to overcome subchannel interference. Chaw-s and Compello-s algorithms have been implemented to obtain a bit and power allocation for each subcarrier assuming instantaneous channel knowledge. The adaptive loaded SVD-STBC scheme is capable of providing both full-rate and full-diversity for any number of transmit antennas. The effectiveness of these techniques has demonstrated through the simulation of an Adaptive loaded SVDSTBC system, and the comparison shown that the proposed algorithms ensure better performance in the case of MIMO.

Keywords: OFDM, MIMO, SVD, STBC, Adaptive Loading.

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247 A Projection Method Based on Extended Krylov Subspaces for Solving Sylvester Equations

Authors: Yiqin Lin, Liang Bao, Yimin Wei

Abstract:

In this paper we study numerical methods for solving Sylvester matrix equations of the form AX +XBT +CDT = 0. A new projection method is proposed. The union of Krylov subspaces in A and its inverse and the union of Krylov subspaces in B and its inverse are used as the right and left projection subspaces, respectively. The Arnoldi-like process for constructing the orthonormal basis of the projection subspaces is outlined. We show that the approximate solution is an exact solution of a perturbed Sylvester matrix equation. Moreover, exact expression for the norm of residual is derived and results on finite termination and convergence are presented. Some numerical examples are presented to illustrate the effectiveness of the proposed method.

Keywords: Arnoldi process, Krylov subspace, Iterative method, Sylvester equation, Dissipative matrix.

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246 Quantification of Periodicities in Fugitive Emission of Gases from Lyari Waterway

Authors: Rana Khalid Naeem, Asif Mansoor

Abstract:

Periodicities in the environmetric time series can be idyllically assessed by utilizing periodic models. In this communication fugitive emission of gases from open sewer channel Lyari which follows periodic behaviour are approximated by employing periodic autoregressive model of order p. The orders of periodic model for each season are selected through the examination of periodic partial autocorrelation or information criteria. The parameters for the selected order of season are estimated individually for each emitted air toxin. Subsequently, adequacies of fitted models are established by examining the properties of the residual for each season. These models are beneficial for schemer and administrative bodies for the improvement of implemented policies to surmount future environmental problems.

Keywords: Exchange of Gases, Goodness of Fit, Open Sewer Channel, PAR(p) Models, Periodicities, Season Wise Models.

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245 Flagging Critical Components to Prevent Transient Faults in Real-Time Systems

Authors: Muhammad Sheikh Sadi, D. G. Myers, Cesar Ortega Sanchez

Abstract:

This paper proposes the use of metrics in design space exploration that highlight where in the structure of the model and at what point in the behaviour, prevention is needed against transient faults. Previous approaches to tackle transient faults focused on recovery after detection. Almost no research has been directed towards preventive measures. But in real-time systems, hard deadlines are performance requirements that absolutely must be met and a missed deadline constitutes an erroneous action and a possible system failure. This paper proposes the use of metrics to assess the system design to flag where transient faults may have significant impact. These tools then allow the design to be changed to minimize that impact, and they also flag where particular design techniques – such as coding of communications or memories – need to be applied in later stages of design.

Keywords: Criticality, Metrics, Real-Time Systems, Transient Faults.

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244 A Multi-Agent Simulation of Serious Games to Predict Their Impact on E-Learning Processes

Authors: Ibtissem Daoudi, Raoudha Chebil, Wided Lejouad Chaari

Abstract:

Serious games constitute actually a recent and attractive way supposed to replace the classical boring courses. However, the choice of the adapted serious game to a specific learning environment remains a challenging task that makes teachers unwilling to adopt this concept. To fill this gap, we present, in this paper, a multi-agent-based simulator allowing to predict the impact of a serious game integration in a learning environment given several game and players characteristics. As results, the presented tool gives intensities of several emotional aspects characterizing learners reactions to the serious game adoption. The presented simulator is tested to predict the effect of basing a coding course on the serious game ”CodeCombat”. The obtained results are compared with feedbacks of using the same serious game in a real learning process.

Keywords: Emotion, learning process, multi-agent simulation, serious games.

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243 A Novel Compression Algorithm for Electrocardiogram Signals based on Wavelet Transform and SPIHT

Authors: Sana Ktata, Kaïs Ouni, Noureddine Ellouze

Abstract:

Electrocardiogram (ECG) data compression algorithm is needed that will reduce the amount of data to be transmitted, stored and analyzed, but without losing the clinical information content. A wavelet ECG data codec based on the Set Partitioning In Hierarchical Trees (SPIHT) compression algorithm is proposed in this paper. The SPIHT algorithm has achieved notable success in still image coding. We modified the algorithm for the one-dimensional (1-D) case and applied it to compression of ECG data. By this compression method, small percent root mean square difference (PRD) and high compression ratio with low implementation complexity are achieved. Experiments on selected records from the MIT-BIH arrhythmia database revealed that the proposed codec is significantly more efficient in compression and in computation than previously proposed ECG compression schemes. Compression ratios of up to 48:1 for ECG signals lead to acceptable results for visual inspection.

Keywords: Discrete Wavelet Transform, ECG compression, SPIHT.

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242 A Support System Applicable to Multiple APIs for Haptic VR Application Designers

Authors: Masaharu Isshiki, Kenji Murakami, Shun Ido

Abstract:

This paper describes a proposed support system which enables applications designers to effectively create VR applications using multiple haptic APIs. When the VR designers create applications, it is often difficult to handle and understand many parameters and functions that have to be set in the application program using documentation manuals only. This complication may disrupt creative imagination and result in inefficient coding. So, we proposed the support application which improved the efficiency of VR applications development and provided the interactive components of confirmation of operations with haptic sense previously. In this paper, we describe improvements of our former proposed support application, which was applicable to multiple APIs and haptic devices, and evaluate the new application by having participants complete VR program. Results from a preliminary experiment suggest that our application facilitates creation of VR applications.

Keywords: VR application, Support system, Haptic devices, Haptic APIs.

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241 A New Routing Algorithm: MIRAD

Authors: Amir Gholami Pastaki, Ali Reza Sahab, Seyed Mehdi Sadeghi

Abstract:

LSP routing is among the prominent issues in MPLS networks traffic engineering. The objective of this routing is to increase number of the accepted requests while guaranteeing the quality of service (QoS). Requested bandwidth is the most important QoS criterion that is considered in literatures, and a various number of heuristic algorithms have been presented with that regards. Many of these algorithms prevent flows through bottlenecks of the network in order to perform load balancing, which impedes optimum operation of the network. Here, a modern routing algorithm is proposed as MIRAD: having a little information of the network topology, links residual bandwidth, and any knowledge of the prospective requests it provides every request with a maximum bandwidth as well as minimum end-to-end delay via uniform load distribution across the network. Simulation results of the proposed algorithm show a better efficiency in comparison with similar algorithms.

Keywords: new generation networks, QoS, traffic engineering, MPLS, QoS based routing, LSP

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240 Influence of High Speed Parameters on the Quality of Machined Surface

Authors: Jana Novakova, Lenka Petrkovska, Josef Brychta, Robert Cep, Lenka Ocenasova

Abstract:

The contribution is dealing with the influence of high speed parameters on the quality of machined surface. In general the principle of high speed cutting lies in achieving faster machine times with concurrent increase in accuracy and quality of the machined areas in largely irregular, mathematically hard to define shapes. High speed machining is a highly effective method of machining with the following goals: increasing of machining productivity, increasing of quality of the machined surface, improving of machining economy, improving of ecological aspects of machining. This article is based on an experiment performed by the Department of Machining and Assembly of the Faculty of Mechanical Engineering of VŠBTechnical University of Ostrava.

Keywords: High speed cutting, measurement, surface integrity, surface roughness, residual stress/

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239 Hybrid Hierarchical Routing Protocol for WSN Lifetime Maximization

Authors: H. Aoudia, Y. Touati, E. H. Teguig, A. Ali Cherif

Abstract:

Conceiving and developing routing protocols for wireless sensor networks requires considerations on constraints such as network lifetime and energy consumption. In this paper, we propose a hybrid hierarchical routing protocol named HHRP combining both clustering mechanism and multipath optimization taking into account residual energy and RSSI measures. HHRP consists of classifying dynamically nodes into clusters where coordinators nodes with extra privileges are able to manipulate messages, aggregate data and ensure transmission between nodes according to TDMA and CDMA schedules. The reconfiguration of the network is carried out dynamically based on a threshold value which is associated with the number of nodes belonging to the smallest cluster. To show the effectiveness of the proposed approach HHRP, a comparative study with LEACH protocol is illustrated in simulations.

Keywords: Routing protocols, energy optimization, clustering.

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238 Physical and Thermo-Physical Properties of High Strength Concrete Containing Raw Rice Husk after High Temperature Effect

Authors: B. Akturk, N. Yuzer, N. Kabay

Abstract:

High temperature is one of the most detrimental effects that cause important changes in concrete’s mechanical, physical, and thermo-physical properties. As a result of these changes, especially high strength concrete (HSC), may exhibit damages such as cracks and spallings. To overcome this problem, incorporating polymer fibers such as polypropylene (PP) in concrete is a very well-known method. In this study, using RRH, as a sustainable material, instead of PP fiber in HSC to prevent spallings and improve physical and thermo-physical properties were investigated. Therefore, seven HSC mixtures with 0.25 water to binder ratio were prepared incorporating silica fume and blast furnace slag. PP and RRH were used at 0.2-0.5% and 0.5-3% by weight of cement, respectively. All specimens were subjected to high temperatures (20 (control), 300, 600 and 900˚C) with a heating rate of 2.5˚C/min and after cooling, residual physical and thermo-physical properties were determined.

Keywords: High temperature, high strength concrete, polypropylene fiber, raw rice husk, thermo-physical properties.

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237 MiRNAs as Regulators of Tumour Suppressor Expression

Authors: Olga A. Berillo, Gaukhar K. Baidildinova, Аnatoliy Т. Ivashchenko

Abstract:

Tumour suppressors are key participants in the prevention of cancer. Regulation of their expression through miRNAs is important for comprehensive translation inhibition of tumour suppressors and elucidation of carcinogenesis mechanisms. We studies the possibility of 1521 miRNAs to bind with 873 mRNAs of human tumour suppressors using RNAHybrid 2.1 and ERNAhybrid programmes. Only 978 miRNAs were found to be translational regulators of 812 mRNAs, and 61 mRNAs did not have any miRNA binding sites. Additionally, 45.9% of all miRNA binding sites were located in coding sequences (CDSs), 33.8% were located in 3' untranslated region (UTR), and 20.3% were located in the 5'UTR. MiRNAs binding with more than 50 target mRNAs and mRNAs binding with several miRNAs were selected. Hsa-miR-5096 had 15 perfectly complementary binding sites with mRNAs of 14 tumour suppressors. These newly indentified miRNA binding sites can be used in the development of medicines (anti-sense therapies) for cancer treatment.

Keywords: Exonic miRNA, intergenic miRNA, intronic miRNA, tumor suppressor.

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