Search results for: Seyed Mahmoud Tabatabaei
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 665

Search results for: Seyed Mahmoud Tabatabaei

545 Assessment of Breast, Lung and Liver Effective Doses in Heart Imaging by CT-Scan 128 Dual Sources with Use of TLD-100 in RANDO Phantom

Authors: Seyedeh Sepideh Amini, Navideh Aghaei Amirkhizi, Seyedeh Paniz Amini, Seyed Soheil Sayyahi, Mohammad Reza Davar Panah

Abstract:

CT-Scan is one of the lateral and sectional imaging methods that produce 3D-images with use of rotational x-ray tube around central axis. This study is about evaluation and calculation of effective doses around heart organs such as breast, lung and liver with CT-Scan 128 dual sources with TLD_100 and RANDO Phantom by spiral, flash and conventional protocols. In results, it is showed that in spiral protocol organs have maximum effective dose and minimum in flash protocol. Thus flash protocol advised for children and risk persons.

Keywords: X-ray computed tomography, dosimetry, TLD-100, RANDO, phantom

Procedia PDF Downloads 452
544 Polymerization: An Alternative Technology for Heavy Metal Removal

Authors: M. S. Mahmoud

Abstract:

In this paper, the adsorption performance of a novel environmental friendly material, calcium alginate gel beads as a non-conventional technique for the successful removal of copper ions from aqueous solution are reported on. Batch equilibrium studies were carried out to evaluate the adsorption capacity and process parameters such as pH, adsorbent dosages, initial metal ion concentrations, stirring rates and contact times. It was observed that the optimum pH for maximum copper ions adsorption was at pH 5.0. For all contact times, an increase in copper ions concentration resulted in decrease in the percent of copper ions removal. Langmuir and Freundlich's isothermal models were used to describe the experimental adsorption. Adsorbent was characterization using Fourier transform-infrared (FT-IR) spectroscopy and Transmission electron microscopy (TEM).

Keywords: adsorption, alginate polymer, isothermal models, equilibrium

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543 Analyzing the Effect of Ambient Temperature and Loads Power Factor on Electric Generator Power Rating

Authors: Ahmed Elsebaay, Maged A. Abu Adma, Mahmoud Ramadan

Abstract:

This study presents a technique clarifying the effect of ambient air temperature and loads power factor changing from standard values on electric generator power rating. The study introduces an optimized technique for selecting the correct electric generator power rating for certain application and operating site ambient temperature. The de-rating factors due to the previous effects will be calculated to be applied on a generator to select its power rating accurately to avoid unsafe operation and save its lifetime. The information in this paper provides a simple, accurate, and general method for synchronous generator selection and eliminates common errors.

Keywords: ambient temperature, de-rating factor, electric generator, power factor

Procedia PDF Downloads 330
542 ANN Modeling for Cadmium Biosorption from Potable Water Using a Packed-Bed Column Process

Authors: Dariush Jafari, Seyed Ali Jafari

Abstract:

The recommended limit for cadmium concentration in potable water is less than 0.005 mg/L. A continuous biosorption process using indigenous red seaweed, Gracilaria corticata, was performed to remove cadmium from the potable water. The process was conducted under fixed conditions and the breakthrough curves were achieved for three consecutive sorption-desorption cycles. A modeling based on Artificial Neural Network (ANN) was employed to fit the experimental breakthrough data. In addition, a simplified semi empirical model, Thomas, was employed for this purpose. It was found that ANN well described the experimental data (R2>0.99) while the Thomas prediction were a bit less successful with R2>0.97. The adjusted design parameters using the nonlinear form of Thomas model was in a good agreement with the experimentally obtained ones. The results approve the capability of ANN to predict the cadmium concentration in potable water.

Keywords: ANN, biosorption, cadmium, packed-bed, potable water

Procedia PDF Downloads 404
541 Optimal Planning of Dispatchable Distributed Generators for Power Loss Reduction in Unbalanced Distribution Networks

Authors: Mahmoud M. Othman, Y. G. Hegazy, A. Y. Abdelaziz

Abstract:

This paper proposes a novel heuristic algorithm that aims to determine the best size and location of distributed generators in unbalanced distribution networks. The proposed heuristic algorithm can deal with the planning cases where power loss is to be optimized without violating the system practical constraints. The distributed generation units in the proposed algorithm is modeled as voltage controlled node with the flexibility to be converted to constant power factor node in case of reactive power limit violation. The proposed algorithm is implemented in MATLAB and tested on the IEEE 37 -node feeder. The results obtained show the effectiveness of the proposed algorithm.

Keywords: distributed generation, heuristic approach, optimization, planning

Procedia PDF Downloads 498
540 Non-factoid Arabic Question-Answering Systems: A Review of Existing Studies, Research Issues, and Future Trends

Authors: Aya Mousa, Mahmoud Alsaheb

Abstract:

Question Answering System (QAS) aims to provide the most suitable answer to the user's question in any natural language. In the recent future, it will be a future version of web search. Much research has already been done on answering Arabic factoid questions and achieved good accuracy. In contrast, the progress in research on Arabic non-factoid question answering is still immature. In this survey, we summarize, discuss, and compare the existing Arab non-factoid question-answering systems to identify the limitations and the achievements that were accomplished. Furthermore, we investigate the challenges in developing non-factoid Arabic QAS and the possible future improvements. The survey is written to help the researchers to understand the field of Arabic non-factoid QAS and to motivate them to utilize different approaches to develop and enhance the Non-factoid Arabic QAS

Keywords: Arabic question answering system, non-factoid question answering, Arabic NLP, question answering

Procedia PDF Downloads 77
539 Selection of Endophytcs Fungi Isolated from Date Palm, Halotolerants and Productors of Secondary Metabolite

Authors: Fadila Mohamed Mahmoud., Derkaoui I., Krimi Z.

Abstract:

Date palm is a plant which presents a very good adaptation to the difficult conditions of the environment in particular to the drought and saline stress even at high temperatures. This adaptation is related on the biology of the plant and to the presence of a microflora endophyte which live inside its tissues. Fifteen endophytics fungi isolated from date palm were tested in vitro in the presence of various NaCl concentrations to select halotolerantes isolates. These same endophytes were tested for their colonizing capacity by the description of the production of secondary metabolites more particularly the enzymes (pectinases, proteases, and phosphorylases), and the production of antibiotics and growth hormones. Significant difference was observed between the isolates with respect to the tests carried out.

Keywords: Date palm, Halotolerantes, endophyte, Secondary metabolites.

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538 Prediction of a Nanostructure Called Porphyrin-Like Buckyball, Using Density Functional Theory and Investigating Electro Catalytic Reduction of Co₂ to Co by Cobalt– Porphyrin-Like Buckyball

Authors: Mohammad Asadpour, Maryam Sadeghi, Mahmoud Jafari

Abstract:

The transformation of carbon dioxide into fuels and commodity chemicals is considered one of the most attractive methods to meet energy demands and reduce atmospheric CO₂ levels. Cobalt complexes have previously shown high faradaic efficiency in the reduction of CO₂ to CO. In this study, a nanostructure, referred to as a porphyrin-like buckyball, is simulated and analyzed for its electrical properties. The investigation aims to understand the unique characteristics of this material and its potential applications in electronic devices. Through computational simulations and analysis, the electrocatalytic reduction of CO₂ to CO by Cobalt-porphyrin-like buckyball is explored. The findings of this study offer valuable insights into the electrocatalytic properties of this predicted structure, paving the way for further research and development in the field of nanotechnology.

Keywords: porphyrin-like buckyball, DFT, nanomaterials, CO₂ to CO

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537 Anticipation of Bending Reinforcement Based on Iranian Concrete Code Using Meta-Heuristic Tools

Authors: Seyed Sadegh Naseralavi, Najmeh Bemani

Abstract:

In this paper, different concrete codes including America, New Zealand, Mexico, Italy, India, Canada, Hong Kong, Euro Code and Britain are compared with the Iranian concrete design code. First, by using Adaptive Neuro Fuzzy Inference System (ANFIS), the codes having the most correlation with the Iranian ninth issue of the national regulation are determined. Consequently, two anticipated methods are used for comparing the codes: Artificial Neural Network (ANN) and Multi-variable regression. The results show that ANN performs better. Predicting is done by using only tensile steel ratio and with ignoring the compression steel ratio.

Keywords: adaptive neuro fuzzy inference system, anticipate method, artificial neural network, concrete design code, multi-variable regression

Procedia PDF Downloads 264
536 Effect of Waste Bottle Chips on Strength Parameters of Silty Soil

Authors: Seyed Abolhasan Naeini, Hamidreza Rahmani

Abstract:

Laboratory consolidated undrained triaxial (CU) tests were carried out to study the strength behavior of silty soil reinforced with randomly plastic waste bottle chips. Specimens mixed with plastic waste chips in triaxial compression tests with 0.25, 0.50, 0.75, 1.0, and 1.25% by dry weight of soil and tree different length including 4, 8, and 12 mm. In all of the samples, the width and thickness of plastic chips were kept constant. According to the results, the amount and size of plastic waste bottle chips played an important role in the increasing of the strength parameters of reinforced silt compared to the pure soil. Because of good results, the suggested method of soil improvement can be used in many engineering problems such as increasing the bearing capacity and settlement reduction in foundations.

Keywords: reinforcement, silt, soil improvement, triaxial test, waste bottle chips

Procedia PDF Downloads 263
535 Targeted Effects of Subsidies on Prices of Selected Commodities in Iran Market

Authors: Sayedramin Hashemianesfehani, Seyed Hossein Hosseinilargani

Abstract:

In this study, we attempt to realize that to what extent the increase in selected commodities in Iran Market is originated from the implementation of the targeted subsidies law. Hence, an econometric model based on existing theories of increasing and transferring prices in order to transferring inflation is developed. In other words, world price index and virtual variables defined for targeted subsidies has significant and positive impact on the producer price index. The obtained results indicated that the targeted subsidies act in Iran has influential long and short-term impacts on producer price indexes. Finally, world prices of dairy products and dairy price with respect to major parameters is carried out to obtain some managerial ‎results.

Keywords: econometric models, targeted subsidies, consumer price index (CPI), producer price index (PPI)

Procedia PDF Downloads 342
534 The Impact of Online Advertising on Consumer Purchase Behaviour Based on Malaysian Organizations

Authors: Naser Zourikalatehsamad, Seyed Abdorreza Payambarpour, Ibrahim Alwashali, Zahra Abdolkarimi

Abstract:

The paper aims to evaluate the effect of online advertising on consumer purchase behavior in Malaysian organizations. The paper has potential to extend and refine theory. A survey was distributed among Students of UTM university during the winter 2014 and 160 responses were collected. Regression analysis was used to test the hypothesized relationships of the model. Result shows that the predictors (cost saving factor, convenience factor and customized product or services) have positive impact on intention to continue seeking online advertising.

Keywords: consumer purchase, convenience, customized product, cost saving, customization, flow theory, mass communication, online advertising ads, online advertising measurement, online advertising mechanism, online intelligence system, self-confidence, willingness to purchase

Procedia PDF Downloads 459
533 Diagnosis Of Static, Dynamic, And Mixed Eccentricity In Line Start Permanent Magnet Synchronous Motor By Using FEM

Authors: Mohamed Moustafa Mahmoud Sedky

Abstract:

In line start permanent magnet synchronous motor, eccentricity is a common fault that can make it necessary to remove the motor from the production line. However, because the motor may be inaccessible, diagnosing the fault is not easy. This paper presents an FEM that identifies different models, static eccentricity, dynamic eccentricity, and mixed eccentricity, at no load and full load. The method overcomes the difficulty of applying FEMs to transient behavior. It simulates motor speed, torque and flux density distribution along the air gap for SE, DE, and ME. This paper represents the various effects of different eccentricities types on the transient performance.

Keywords: line start permanent magnet, synchronous machine, static eccentricity, dynamic eccentricity, mixed eccentricity

Procedia PDF Downloads 350
532 Characterization of Anisotropic Deformation in Sandstones Using Micro-Computed Tomography Technique

Authors: Seyed Mehdi Seyed Alizadeh, Christoph Arns, Shane Latham

Abstract:

Geomechanical characterization of rocks in detail and its possible implications on flow properties is an important aspect of reservoir characterization workflow. In order to gain more understanding of the microstructure evolution of reservoir rocks under stress a series of axisymmetric triaxial tests were performed on two different analogue rock samples. In-situ compression tests were coupled with high resolution micro-Computed Tomography to elucidate the changes in the pore/grain network of the rocks under pressurized conditions. Two outcrop sandstones were chosen in the current study representing a various cementation status of well-consolidated and weakly-consolidated granular system respectively. High resolution images were acquired while the rocks deformed in a purpose-built compression cell. A detailed analysis of the 3D images in each series of step-wise compression tests (up to the failure point) was conducted which includes the registration of the deformed specimen images with the reference pristine dry rock image. Digital Image Correlation (DIC) technique based on the intensity of the registered 3D subsets and particle tracking are utilized to map the displacement fields in each sample. The results suggest the complex architecture of the localized shear zone in well-cemented Bentheimer sandstone whereas for the weakly-consolidated Castlegate sandstone no discernible shear band could be observed even after macroscopic failure. Post-mortem imaging a sister plug from the friable rock upon undergoing continuous compression reveals signs of a shear band pattern. This suggests that for friable sandstones at small scales loading mode may affect the pattern of deformation. Prior to mechanical failure, the continuum digital image correlation approach can reasonably capture the kinematics of deformation. As failure occurs, however, discrete image correlation (i.e. particle tracking) reveals superiority in both tracking the grains as well as quantifying their kinematics (in terms of translations/rotations) with respect to any stage of compaction. An attempt was made to quantify the displacement field in compression using continuum Digital Image Correlation which is based on the reference and secondary image intensity correlation. Such approach has only been previously applied to unconsolidated granular systems under pressure. We are applying this technique to sandstones with various degrees of consolidation. Such element of novelty will set the results of this study apart from previous attempts to characterize the deformation pattern in consolidated sands.

Keywords: deformation mechanism, displacement field, shear behavior, triaxial compression, X-ray micro-CT

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531 Experimental Procedure of Identifying Ground Type by Downhole Test: A Case Study

Authors: Seyed Abolhassan Naeini, Maedeh Akhavan Tavakkoli

Abstract:

Evaluating the shear wave velocity (V_s) and primary wave velocity (Vₚ) is necessary to identify the ground type of the site. Identifying the soil type based on different codes can affect the dynamic analysis of geotechnical properties. This study aims to separate the underground layers at the project site based on the shear wave and primary wave velocity (Sₚ) in different depths and determine dynamic elastic modulus based on the shear wave velocity. Bandar Anzali is located in a tectonically very active area. Several active faults surround the study site. In this case, a field investigation of downhole testing is conducted as a geophysics method to identify the ground type.

Keywords: downhole, geophysics, shear wave velocity, case-study

Procedia PDF Downloads 116
530 Calculation of Stress Intensity Factors in Rotating Disks Containing 3D Semi-Elliptical Cracks

Authors: Mahdi Fakoor, Seyed Mohammad Navid Ghoreishi

Abstract:

Initiation and propagation of cracks may cause catastrophic failures in rotating disks, and hence determination of fracture parameter in rotating disks under the different working condition is very important issue. In this paper, a comprehensive study of stress intensity factors in rotating disks containing 3D semi-elliptical cracks under the different working condition is investigated. In this regard, after verification of modeling and analytical procedure, the effects of mechanical properties, rotational velocity, and orientation of cracks on Stress Intensity Factors (SIF) in rotating disks under centrifugal loading are investigated. Also, the effects of using composite patch in reduction of SIF in rotating disks are studied. By that way, the effects of patching design variables like mechanical properties, thickness, and ply angle are investigated individually.

Keywords: stress intensity factor, semi-elliptical crack, rotating disk, finite element analysis (FEA)

Procedia PDF Downloads 339
529 Effect of Hot Equal Channel Angular Pressing Process on Mechanical Properties of Commercial Pure Titanium

Authors: Seyed Ata Khalkhkali Sharifi, Gholamhossein Majzoubi, Farhad Abroush

Abstract:

Developing mechanical properties of pure titanium has been reviewed in this paper by using ECAP process. At the first step of this article, the experimental samples were prepared as mentioned in the standards. Then pure grade 2 Ti was processed via equal-channel angular pressing (ECAp) for 2 passes following route-A at 400°C. After processing, the microstructural evolution, tensile, fatigue, hardness properties and wear behavior were investigated. Finally, the effect of ECAP process on these samples was analyzed. The results showed improvement in strength values with a slight decrease in ductility. The analysis on 30 points within the sample showed hardness increase in each pass. Also, it was concluded that fatigue properties were increased too.

Keywords: equal-channel angular pressing, titanium, mechanical behavior, engineering materials and applications

Procedia PDF Downloads 244
528 Different Biological and Chemical Parameters that Influence the Polyphenols from Some Medicinal Plants in Western Algeria

Authors: Mustapha Mahmoud, Fouzia Toumi Benali, Mohamed Benyahia, Sofiane Bouazza

Abstract:

This work focuses on the influences of biological and chemical parameters on the phenolic compounds such as flavonoids and tannins in different medicinal plants in western Algeria (Papaver rhoeas, Daphnegnidium, Lavandula multifida, Lavandula dentata, Lavandula stoicha, ...). Thus we look the difference between species of the same genus, difference between the different organs of the same species, the influence of environment all temperature influences, time, percentage of solvent on the extraction. Quantification of the phenolic compounds was performed by spectrophotometric method then treated with statistics tools such as variance analysis, multivariant analyzes, response surface methodology). The results show that the polyphenols are influenced by the parameters mentioned.

Keywords: polyphenols, influences, medicinal plants, west Algeria

Procedia PDF Downloads 265
527 The Impact of Gender Inequality on Corruption:Evidence from Politics and Labor Market

Authors: Mahmoud Salari

Abstract:

Corruption and gender inequality are the main topics of interest for both economists and policymakers. This study develops various static and dynamic estimation models to examine the impact of gender inequality in politics and the labor market on corruption using data of 170 countries from 1998 to 2014. This study uses two most reliable corruption indexes, including Corruption Perceptions Index (CPI) and Corruption Control (CC), to evaluate corruption levels across countries. The results indicate that gender inequality in politics has a strong impact on corruption level, and those countries that have larger/smaller gender inequality in their parliaments are faced with higher/lower corruption, respectively. Meanwhile, there is no enough evidence that supports the relationship between gender inequality in the labor market and corruption, and the results indicate that gender inequality in the labor market is not directly linked to the corruption level.

Keywords: corruption, female labor force participation, politics, gender inequality

Procedia PDF Downloads 165
526 A Model Predictive Control Based Virtual Active Power Filter Using V2G Technology

Authors: Mahdi Zolfaghari, Seyed Hossein Hosseinian, Hossein Askarian Abyaneh, Mehrdad Abedi

Abstract:

This paper presents a virtual active power filter (VAPF) using vehicle to grid (V2G) technology to maintain power quality requirements. The optimal discrete operation of the power converter of electric vehicle (EV) is based on recognizing desired switching states using the model predictive control (MPC) algorithm. A fast dynamic response, lower total harmonic distortion (THD) and good reference tracking performance are realized through the presented control strategy. The simulation results using MATLAB/Simulink validate the effectiveness of the scheme in improving power quality as well as good dynamic response in power transferring capability.

Keywords: electric vehicle, model predictive control, power quality, V2G technology, virtual active power filter

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525 Evaluation Metrics for Machine Learning Techniques: A Comprehensive Review and Comparative Analysis of Performance Measurement Approaches

Authors: Seyed-Ali Sadegh-Zadeh, Kaveh Kavianpour, Hamed Atashbar, Elham Heidari, Saeed Shiry Ghidary, Amir M. Hajiyavand

Abstract:

Evaluation metrics play a critical role in assessing the performance of machine learning models. In this review paper, we provide a comprehensive overview of performance measurement approaches for machine learning models. For each category, we discuss the most widely used metrics, including their mathematical formulations and interpretation. Additionally, we provide a comparative analysis of performance measurement approaches for metric combinations. Our review paper aims to provide researchers and practitioners with a better understanding of performance measurement approaches and to aid in the selection of appropriate evaluation metrics for their specific applications.

Keywords: evaluation metrics, performance measurement, supervised learning, unsupervised learning, reinforcement learning, model robustness and stability, comparative analysis

Procedia PDF Downloads 41
524 Optimization of FGM Sandwich Beams Using Imperialist Competitive Algorithm

Authors: Saeed Kamarian, Mahmoud Shakeri

Abstract:

Sandwich structures are used in a variety of engineering applications including aircraft, construction and transportation where strong, stiff and light structures are required. In this paper, frequency maximization of Functionally Graded Sandwich (FGS) beams resting on Pasternak foundations is investigated. A generalized power-law distribution with four parameters is considered for material distribution through the thicknesses of face layers. Since the search space is large, the optimization processes becomes so complicated and too much time consuming. Thus a novel meta–heuristic called Imperialist Competitive Algorithm (ICA) which is a socio-politically motivated global search strategy is implemented to improve the speed of optimization process. Results show the success of applying ICA for engineering problems especially for design optimization of FGM sandwich beams.

Keywords: sandwich beam, functionally graded materials, optimization, imperialist competitive algorithm

Procedia PDF Downloads 546
523 Investigating the Efficiency of Stratified Double Median Ranked Set Sample for Estimating the Population Mean

Authors: Mahmoud I. Syam

Abstract:

Stratified double median ranked set sampling (SDMRSS) method is suggested for estimating the population mean. The SDMRSS is compared with the simple random sampling (SRS), stratified simple random sampling (SSRS), and stratified ranked set sampling (SRSS). It is shown that SDMRSS estimator is an unbiased of the population mean and more efficient than SRS, SSRS, and SRSS. Also, by SDMRSS, we can increase the efficiency of mean estimator for specific value of the sample size. SDMRSS is applied on real life examples, and the results of the example agreed the theoretical results.

Keywords: efficiency, double ranked set sampling, median ranked set sampling, ranked set sampling, stratified

Procedia PDF Downloads 226
522 A Secure Routing Algorithm for ‎Underwater Wireless Sensor Networks

Authors: Seyed Mahdi Jameii

Abstract:

Underwater wireless sensor networks have been attracting the interest of many ‎researchers lately, and the past three decades have beheld the rapid progress of ‎underwater acoustic communication. One of the major problems in underwater wireless ‎sensor networks is how to transfer data from the moving node to the base stations and ‎choose the optimized route for data transmission. Secure routing in underwater ‎wireless sensor network (UWCNs) is necessary for packet delivery. Some routing ‎protocols are proposed for underwater wireless sensor networks. However, a few ‎researches have been done on secure routing in underwater sensor networks. In this ‎article, a secure routing protocol is provided to resist against wormhole and sybil ‎attacks. The results indicated acceptable performance in terms of increasing the packet ‎delivery ratio with regards to the attacks, increasing network lifetime by creating ‎balance in the network energy consumption, high detection rates against the attacks, ‎and low-end to end delay.‎

Keywords: attacks, routing, security, underwater wireless sensor networks

Procedia PDF Downloads 394
521 Optimization Method of Dispersed Generation in Electrical Distribution Systems

Authors: Mahmoud Samkan

Abstract:

Dispersed Generation (DG) is a promising solution to many power system problems such as voltage regulation and power loss. This paper proposes a heuristic two-step method to optimize the location and size of DG for reducing active power losses and, therefore, improve the voltage profile in radial distribution networks. In addition to a DG placed at the system load gravity center, this method consists in assigning a DG to each lateral of the network. After having determined the central DG placement, the location and size of each lateral DG are predetermined in the first step. The results are then refined in the second step. This method is tested for 33-bus system for 100% DG penetration. The results obtained are compared with those of other methods found in the literature.

Keywords: optimal location, optimal size, dispersed generation (DG), radial distribution networks, reducing losses

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520 A Serum- And Feeder-Free Culture System for the Robust Generation of Human Stem Cell-Derived CD19+ B Cells and Antibody-Secreting Cells

Authors: Kirsten Wilson, Patrick M. Brauer, Sandra Babic, Diana Golubeva, Jessica Van Eyk, Tinya Wang, Avanti Karkhanis, Tim A. Le Fevre, Andy I. Kokaji, Allen C. Eaves, Sharon A. Louis, , Nooshin Tabatabaei-Zavareh

Abstract:

Long-lived plasma cells are rare, non-proliferative B cells generated from antibody-secreting cells (ASCs) following an immune response to protect the host against pathogen re-exposure. Despite their therapeutic potential, the lack of in vitro protocols in the field makes it challenging to use B cells as a cellular therapeutic tool. As a result, there is a need to establish robust and reproducible methods for the generation of B cells. To address this, we have developed a culture system for generating B cells from hematopoietic stem and/or progenitor cells (HSPCs) derived from human umbilical cord blood (CB) or pluripotent stem cells (PSCs). HSPCs isolated from CB were cultured using the StemSpan™ B Cell Generation Kit and produced CD19+ B cells at a frequency of 23.2 ± 1.5% and 59.6 ± 2.3%, with a yield of 91 ± 11 and 196 ± 37 CD19+ cells per input CD34+ cell on culture days 28 and 35, respectively (n = 50 - 59). CD19+IgM+ cells were detected at a frequency of 31.2 ± 2.6% and were produced at a yield of 113 ± 26 cells per input CD34+ cell on culture day 35 (n = 50 - 59). The B cell receptor loci of CB-derived B cells were sequenced to confirm V(D)J gene rearrangement. ELISpot analysis revealed that ASCs were generated at a frequency of 570 ± 57 per 10,000 day 35 cells, with an average IgM+ ASC yield of 16 ± 2 cells per input CD34+ cell (n = 33 - 42). PSC-derived HSPCs were generated using the STEMdiff™ Hematopoietic - EB reagents and differentiated to CD10+CD19+ B cells with a frequency of 4 ± 0.8% after 28 days of culture (n = 37, 1 embryonic and 3 induced pluripotent stem cell lines tested). Subsequent culture of PSC-derived HSPCs increased CD19+ frequency and generated ASCs from 1 - 2 iPSC lines. This method is the first report of a serum- and feeder-free system for the generation of B cells from CB and PSCs, enabling further B lineage-specific research for potential future clinical applications.

Keywords: stem cells, B cells, immunology, hematopoiesis, PSC, differentiation

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519 Acute Hepatotoxicity of Nano and Micro-Sized Iron Particles in Adult Albino Rats

Authors: Ghada Hasabo, Mahmoud Saber Elbasiouny, Mervat Abdelsalam, Sherin Ghaleb, Niveen Eldessouky

Abstract:

In the near future, nanotechnology is envisaged for large scale use. Hence health and safety issues of nanoparticles should be promptly addressed. In the present study the acute hepatoxicity assessment due to high single oral dose of nano iron and micro iron particles were studied. The normal daily activities, biochemical alterations, blood coagulation, histopathological changes in Wister rats were the aspect of the toxicological assessment.This work found that significant alterations in biochemical enzymes (serum iron level, liver enzymes, albumin, and bilirubin levels), blood coagulation (PT, PC, INR), and histopathological changes occurred more prominently in the nano iron particle treated group.

Keywords: nanobiotechnology, nanosystems, nanomaterials, nanotechnology

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518 The Impact of Knowledge Management on Different Innovation Types in Small and Medium Enterprises

Authors: Shahnaz Piroozfar, Seyed Arash Halajzadeh, Abouzar Ilkhani

Abstract:

Nowadays, in unpredictable business environments, enterprises face a great challenge to meet customer’s requirements. The performance of an enterprise has a significant impact on its activities and has to be evaluated continuously. One of the most important indicators to evaluate performance is named ‘innovation’. There are various indicators of innovation in the product/service sectors. These cause different innovation types to emerge, in product sectors. Additionally there are basic enablers to these innovation types, including an innovative culture, a customer oriented organizational culture, etc. Also one of these enablers is called enterprise system, which includes: SCM, CRM, ERP, KM etc. Knowledge management as a solution is a necessity in a competitive world. Implementation solutions such as KM are expensive, so enterprises need to answer how KM systems affect different performance indicators like innovation. This paper aims to develop a model to evaluate the impact of KM on innovation in SMEs.

Keywords: innovation, knowledge management, SMEs, enterprise

Procedia PDF Downloads 677
517 Annual Water Level Simulation Using Support Vector Machine

Authors: Maryam Khalilzadeh Poshtegal, Seyed Ahmad Mirbagheri, Mojtaba Noury

Abstract:

In this paper, by application of the input yearly data of rainfall, temperature and flow to the Urmia Lake, the simulation of water level fluctuation were applied by means of three models. According to the climate change investigation the fluctuation of lakes water level are of high interest. This study investigate data-driven models, support vector machines (SVM), SVM method which is a new regression procedure in water resources are applied to the yearly level data of Lake Urmia that is the biggest and the hyper saline lake in Iran. The evaluated lake levels are found to be in good correlation with the observed values. The results of SVM simulation show better accuracy and implementation. The mean square errors, mean absolute relative errors and determination coefficient statistics are used as comparison criteria.

Keywords: simulation, water level fluctuation, urmia lake, support vector machine

Procedia PDF Downloads 343
516 Investigation on the Effect of Sugarcane Bagasse/HDPE Composition on the Screw Withdrawal Resistance of Injection Molded Parts

Authors: Seyed Abdol Mohammad Rezavand, Mohammad Nikbakhsh

Abstract:

Withdrawal resistance of screws driven into HDPE/Sugarcane Bagasse injection molded parts was investigated. After chemical treatment and drying, SCB was pre-mixed with HDPE using twin extruder. The resulting granules are used in producing samples in injection molding machine. SCB with the quantity of %10, %20, and %30 was used. By using a suitable fixture, screw heads can take with tensile test machine grips. Parts with screws in the center and edge were fasten together. Then, withdrawal resistance was measured with tensile test machine. Injection gate is at the one edge of the part. The results show that by increasing SCB content in composite, the withdrawal resistance is decreased. Furthermore, the withdrawal resistance at the edges (near injection gate and the end of the filling path of mold cavity) is more than that of the center.

Keywords: polyethylene, sugarcane bagasse, wood plastic, screw, withdrawal resistance

Procedia PDF Downloads 560