Search results for: limit detection and avoidance
228 Protein Profiling in Alanine Aminotransferase Induced Patient cohort using Acetaminophen
Authors: Gry M, Bergström J, Lengquist J, Lindberg J, Drobin K, Schwenk J, Nilsson P, Schuppe-Koistinen I.
Abstract:
Sensitive and predictive DILI (Drug Induced Liver Injury) biomarkers are needed in drug R&D to improve early detection of hepatotoxicity. The discovery of DILI biomarkers that demonstrate the predictive power to identify individuals at risk to DILI would represent a major advance in the development of personalized healthcare approaches. In this healthy volunteer acetaminophen study (4g/day for 7 days, with 3 monitored nontreatment days before and 4 after), 450 serum samples from 32 subjects were analyzed using protein profiling by antibody suspension bead arrays. Multiparallel protein profiles were generated using a DILI target protein array with 300 antibodies, where the antibodies were selected based on previous literature findings of putative DILI biomarkers and a screening process using pre dose samples from the same cohort. Of the 32 subjects, 16 were found to develop an elevated ALT value (2Xbaseline, responders). Using the plasma profiling approach together with multivariate statistical analysis some novel findings linked to lipid metabolism were found and more important, endogenous protein profiles in baseline samples (prior to treatment) with predictive power for ALT elevations were identified.Keywords: DILI, Plasma profiling, PLSDA, Randomforest.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1304227 Joint Training Offer Selection and Course Timetabling Problems: Models and Algorithms
Authors: Gianpaolo Ghiani, Emanuela Guerriero, Emanuele Manni, Alessandro Romano
Abstract:
In this article, we deal with a variant of the classical course timetabling problem that has a practical application in many areas of education. In particular, in this paper we are interested in high schools remedial courses. The purpose of such courses is to provide under-prepared students with the skills necessary to succeed in their studies. In particular, a student might be under prepared in an entire course, or only in a part of it. The limited availability of funds, as well as the limited amount of time and teachers at disposal, often requires schools to choose which courses and/or which teaching units to activate. Thus, schools need to model the training offer and the related timetabling, with the goal of ensuring the highest possible teaching quality, by meeting the above-mentioned financial, time and resources constraints. Moreover, there are some prerequisites between the teaching units that must be satisfied. We first present a Mixed-Integer Programming (MIP) model to solve this problem to optimality. However, the presence of many peculiar constraints contributes inevitably in increasing the complexity of the mathematical model. Thus, solving it through a general-purpose solver may be performed for small instances only, while solving real-life-sized instances of such model requires specific techniques or heuristic approaches. For this purpose, we also propose a heuristic approach, in which we make use of a fast constructive procedure to obtain a feasible solution. To assess our exact and heuristic approaches we perform extensive computational results on both real-life instances (obtained from a high school in Lecce, Italy) and randomly generated instances. Our tests show that the MIP model is never solved to optimality, with an average optimality gap of 57%. On the other hand, the heuristic algorithm is much faster (in about the 50% of the considered instances it converges in approximately half of the time limit) and in many cases allows achieving an improvement on the objective function value obtained by the MIP model. Such an improvement ranges between 18% and 66%.Keywords: Heuristic, MIP model, Remedial course, School, Timetabling.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1621226 Enhancing the Performance of H.264/AVC in Adaptive Group of Pictures Mode Using Octagon and Square Search Pattern
Authors: S. Sowmyayani, P. Arockia Jansi Rani
Abstract:
This paper integrates Octagon and Square Search pattern (OCTSS) motion estimation algorithm into H.264/AVC (Advanced Video Coding) video codec in Adaptive Group of Pictures (AGOP) mode. AGOP structure is computed based on scene change in the video sequence. Octagon and square search pattern block-based motion estimation method is implemented in inter-prediction process of H.264/AVC. Both these methods reduce bit rate and computational complexity while maintaining the quality of the video sequence respectively. Experiments are conducted for different types of video sequence. The results substantially proved that the bit rate, computation time and PSNR gain achieved by the proposed method is better than the existing H.264/AVC with fixed GOP and AGOP. With a marginal gain in quality of 0.28dB and average gain in bitrate of 132.87kbps, the proposed method reduces the average computation time by 27.31 minutes when compared to the existing state-of-art H.264/AVC video codec.Keywords: Block Distortion Measure, Block Matching Algorithms, H.264/AVC, Motion estimation, Search patterns, Shot cut detection.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1713225 Automotive 3-Microphone Noise Canceller in a Frequently Moving Noise Source Environment
Authors: Z. Qi, T. J. Moir
Abstract:
A combined three-microphone voice activity detector (VAD) and noise-canceling system is studied to enhance speech recognition in an automobile environment. A previous experiment clearly shows the ability of the composite system to cancel a single noise source outside of a defined zone. This paper investigates the performance of the composite system when there are frequently moving noise sources (noise sources are coming from different locations but are not always presented at the same time) e.g. there is other passenger speech or speech from a radio when a desired speech is presented. To work in a frequently moving noise sources environment, whilst a three-microphone voice activity detector (VAD) detects voice from a “VAD valid zone", the 3-microphone noise canceller uses a “noise canceller valid zone" defined in freespace around the users head. Therefore, a desired voice should be in the intersection of the noise canceller valid zone and VAD valid zone. Thus all noise is suppressed outside this intersection of area. Experiments are shown for a real environment e.g. all results were recorded in a car by omni-directional electret condenser microphones.
Keywords: Signal processing, voice activity detection, noise canceller, microphone array beam forming.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1598224 On Analysis of Boundness Property for ECATNets by Using Rewriting Logic
Authors: Noura Boudiaf, Allaoua Chaoui
Abstract:
To analyze the behavior of Petri nets, the accessibility graph and Model Checking are widely used. However, if the analyzed Petri net is unbounded then the accessibility graph becomes infinite and Model Checking can not be used even for small Petri nets. ECATNets [2] are a category of algebraic Petri nets. The main feature of ECATNets is their sound and complete semantics based on rewriting logic [8] and its language Maude [9]. ECATNets analysis may be done by using techniques of accessibility analysis and Model Checking defined in Maude. But, these two techniques supported by Maude do not work also with infinite-states systems. As a category of Petri nets, ECATNets can be unbounded and so infinite systems. In order to know if we can apply accessibility analysis and Model Checking of Maude to an ECATNet, we propose in this paper an algorithm allowing the detection if the ECATNet is bounded or not. Moreover, we propose a rewriting logic based tool implementing this algorithm. We show that the development of this tool using the Maude system is facilitated thanks to the reflectivity of the rewriting logic. Indeed, the self-interpretation of this logic allows us both the modelling of an ECATNet and acting on it.Keywords: ECATNets, Rewriting Logic, Maude, Finite-stateSystems, Infinite-state Systems, Boundness Property Checking.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1370223 Evaluating Portfolio Performance by Highlighting Network Property and the Sharpe Ratio in the Stock Market
Authors: Zahra Hatami, Hesham Ali, David Volkman
Abstract:
Selecting a portfolio for investing is a crucial decision for individuals and legal entities. In the last two decades, with economic globalization, a stream of financial innovations has rushed to the aid of financial institutions. The importance of selecting stocks for the portfolio is always a challenging task for investors. This study aims to create a financial network to identify optimal portfolios using network centralities metrics. This research presents a community detection technique of superior stocks that can be described as an optimal stock portfolio to be used by investors. By using the advantages of a network and its property in extracted communities, a group of stocks was selected for each of the various time periods. The performance of the optimal portfolios was compared to the famous index. Their Sharpe ratio was calculated in a timely manner to evaluate their profit for making decisions. The analysis shows that the selected potential portfolio from stocks with low centrality measurement can outperform the market; however, they have a lower Sharpe ratio than stocks with high centrality scores. In other words, stocks with low centralities could outperform the S&P500 yet have a lower Sharpe ratio than high central stocks.
Keywords: Portfolio management performance, network analysis, centrality measurements, Sharpe ratio.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 380222 On-line Recognition of Isolated Gestures of Flight Deck Officers (FDO)
Authors: Deniz T. Sodiri, Venkat V S S Sastry
Abstract:
The paper presents an on-line recognition machine (RM) for continuous/isolated, dynamic and static gestures that arise in Flight Deck Officer (FDO) training. RM is based on generic pattern recognition framework. Gestures are represented as templates using summary statistics. The proposed recognition algorithm exploits temporal and spatial characteristics of gestures via dynamic programming and Markovian process. The algorithm predicts corresponding index of incremental input data in the templates in an on-line mode. Accumulated consistency in the sequence of prediction provides a similarity measurement (Score) between input data and the templates. The algorithm provides an intuitive mechanism for automatic detection of start/end frames of continuous gestures. In the present paper, we consider isolated gestures. The performance of RM is evaluated using four datasets - artificial (W TTest), hand motion (Yang) and FDO (tracker, vision-based ). RM achieves comparable results which are in agreement with other on-line and off-line algorithms such as hidden Markov model (HMM) and dynamic time warping (DTW). The proposed algorithm has the additional advantage of providing timely feedback for training purposes.Keywords: On-line Recognition Algorithm, IsolatedDynamic/Static Gesture Recognition, On-line Markovian/DynamicProgramming, Training in Virtual Environments.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1320221 RadMote: A Mobile Framework for Radiation Monitoring in Nuclear Power Plants
Authors: Javier Barbaran, Manuel Dıaz, Inaki Esteve, Bartolome Rubio
Abstract:
Wireless Sensor Networks (WSNs) have attracted the attention of many researchers. This has resulted in their rapid integration in very different areas such as precision agriculture,environmental monitoring, object and event detection and military surveillance. Due to the current WSN characteristics this technology is specifically useful in industrial areas where security, reliability and autonomy are basic, such as nuclear power plants, chemical plants, and others. In this paper we present a system based on WSNs to monitor environmental conditions around and inside a nuclear power plant, specifically, radiation levels. Sensor nodes, equipped with radiation sensors, are deployed in fixed positions throughout the plant. In addition, plant staff are also equipped with mobile devices with higher capabilities than sensors such as for example PDAs able to monitor radiation levels and other conditions around them. The system enables communication between PDAs, which form a Mobile Ad-hoc Wireless Network (MANET), and allows workers to monitor remote conditions in the plant. It is particularly useful during stoppage periods for inspection or in the event of an accident to prevent risk situations.Keywords: MANETs, Mobile computing, Radiation monitoring, Wireless Sensor Networks.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1998220 Machine Vision System for Automatic Weeding Strategy in Oil Palm Plantation using Image Filtering Technique
Authors: Kamarul Hawari Ghazali, Mohd. Marzuki Mustafa, Aini Hussain
Abstract:
Machine vision is an application of computer vision to automate conventional work in industry, manufacturing or any other field. Nowadays, people in agriculture industry have embarked into research on implementation of engineering technology in their farming activities. One of the precision farming activities that involve machine vision system is automatic weeding strategy. Automatic weeding strategy in oil palm plantation could minimize the volume of herbicides that is sprayed to the fields. This paper discusses an automatic weeding strategy in oil palm plantation using machine vision system for the detection and differential spraying of weeds. The implementation of vision system involved the used of image processing technique to analyze weed images in order to recognized and distinguished its types. Image filtering technique has been used to process the images as well as a feature extraction method to classify the type of weed images. As a result, the image processing technique contributes a promising result of classification to be implemented in machine vision system for automated weeding strategy.Keywords: Machine vision, Automatic Weeding Strategy, filter, feature extraction
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1850219 Secure Block-Based Video Authentication with Localization and Self-Recovery
Authors: Ammar M. Hassan, Ayoub Al-Hamadi, Yassin M. Y. Hasan, Mohamed A. A. Wahab, Bernd Michaelis
Abstract:
Because of the great advance in multimedia technology, digital multimedia is vulnerable to malicious manipulations. In this paper, a public key self-recovery block-based video authentication technique is proposed which can not only precisely localize the alteration detection but also recover the missing data with high reliability. In the proposed block-based technique, multiple description coding MDC is used to generate two codes (two descriptions) for each block. Although one block code (one description) is enough to rebuild the altered block, the altered block is rebuilt with better quality by the two block descriptions. So using MDC increases the ratability of recovering data. A block signature is computed using a cryptographic hash function and a doubly linked chain is utilized to embed the block signature copies and the block descriptions into the LSBs of distant blocks and the block itself. The doubly linked chain scheme gives the proposed technique the capability to thwart vector quantization attacks. In our proposed technique , anyone can check the authenticity of a given video using the public key. The experimental results show that the proposed technique is reliable for detecting, localizing and recovering the alterations.Keywords: Authentication, hash function, multiple descriptioncoding, public key encryption, watermarking.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1922218 The Influence of Organic Waste on Vegetable Nutritional Components and Healthy Livelihood, Minna, Niger State, Nigeria
Authors: A. Abdulkadir, A. A. Okhimamhe, Y. M. Bello, H. Ibrahim, D. H. Makun, M. T. Usman
Abstract:
Household waste form a larger proportion of waste generated across the state, accumulation of organic waste is an apparent problem and the existing dump sites could be overstress. Niger state has abundant arable land and water resources thus should be one of the highest producers of agricultural crops in the country. However, the major challenge to agricultural sector today is loss of soil nutrient coupled with high cost of fertilizer. These have continued to increase the use of fertilizer and decomposed solid waste for enhance agricultural yield, which have varying effects on the soil as well a threat to human livelihood. Consequently, vegetable yield samples from poultry droppings, decomposed household waste manure, NPK treatments and control from each replication were subjected to proximate analysis to determine the nutritional and antinutritional component as well as heavy metal concentration. Data collected was analyzed using SPSS software and Randomized complete Block Design means were compared. The result shows that the treatments do not devoid the concentrations of any nutritional components while the anti-nutritional analysis proved that NPK had higher oxalate content than control and organic treats. The concentration of lead and cadmium are within safe permissible level while the mercury level exceeded the FAO/WHO maximum permissible limit for the entire treatments depicts the need for urgent intervention to minimize mercury levels in soil and manure in order to mitigate its toxic effect. Thus, eco-agriculture should be widely accepted and promoted by the stakeholders for soil amendment, higher yield, strategies for sustainable environmental protection, food security, poverty eradication, attainment of sustainable development and healthy livelihood.Keywords: Anti-nutritional, healthy livelihood, nutritional waste, organic waste.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1618217 Theoretical Analysis of Capacities in Dynamic Spatial Multiplexing MIMO Systems
Authors: Imen Sfaihi, Noureddine Hamdi
Abstract:
In this paper, we investigate the study of techniques for scheduling users for resource allocation in the case of multiple input and multiple output (MIMO) packet transmission systems. In these systems, transmit antennas are assigned to one user or dynamically to different users using spatial multiplexing. The allocation of all transmit antennas to one user cannot take full advantages of multi-user diversity. Therefore, we developed the case when resources are allocated dynamically. At each time slot users have to feed back their channel information on an uplink feedback channel. Channel information considered available in the schedulers is the zero forcing (ZF) post detection signal to interference plus noise ratio. Our analysis study concerns the round robin and the opportunistic schemes. In this paper, we present an overview and a complete capacity analysis of these schemes. The main results in our study are to give an analytical form of system capacity using the ZF receiver at the user terminal. Simulations have been carried out to validate all proposed analytical solutions and to compare the performance of these schemes.Keywords: MIMO, scheduling, ZF receiver, spatial multiplexing, round robin scheduling, opportunistic.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1302216 Electro-Thermal Imaging of Breast Phantom: An Experimental Study
Authors: H. Feza Carlak, N. G. Gencer
Abstract:
To increase the temperature contrast in thermal images, the characteristics of the electrical conductivity and thermal imaging modalities can be combined. In this experimental study, it is objected to observe whether the temperature contrast created by the tumor tissue can be improved just due to the current application within medical safety limits. Various thermal breast phantoms are developed to simulate the female breast tissue. In vitro experiments are implemented using a thermal infrared camera in a controlled manner. Since experiments are implemented in vitro, there is no metabolic heat generation and blood perfusion. Only the effects and results of the electrical stimulation are investigated. Experimental study is implemented with two-dimensional models. Temperature contrasts due to the tumor tissues are obtained. Cancerous tissue is determined using the difference and ratio of healthy and tumor images. 1 cm diameter single tumor tissue causes almost 40 °mC temperature contrast on the thermal-breast phantom. Electrode artifacts are reduced by taking the difference and ratio of background (healthy) and tumor images. Ratio of healthy and tumor images show that temperature contrast is increased by the current application.Keywords: Medical diagnostic imaging, breast phantom, active thermography, breast cancer detection.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1479215 Early Diagnosis of Alzheimer's Disease Using a Combination of Images Processing and Brain Signals
Authors: E. Irankhah, M. Zarif, E. Mazrooei Rad, K. Ghandehari
Abstract:
Alzheimer's prevalence is on the rise, and the disease comes with problems like cessation of treatment, high cost of treatment, and the lack of early detection methods. The pathology of this disease causes the formation of protein deposits in the brain of patients called plaque amyloid. Generally, the diagnosis of this disease is done by performing tests such as a cerebrospinal fluid, CT scan, MRI, and spinal cord fluid testing, or mental testing tests and eye tracing tests. In this paper, we tried to use the Medial Temporal Atrophy (MTA) method and the Leave One Out (LOO) cycle to extract the statistical properties of the three Fz, Pz, and Cz channels of ERP signals for early diagnosis of this disease. In the process of CT scan images, the accuracy of the results is 81% for the healthy person and 88% for the severe patient. After the process of ERP signaling, the accuracy of the results for a healthy person in the delta band in the Cz channel is 81% and in the alpha band the Pz channel is 90%. In the results obtained from the signal processing, the results of the severe patient in the delta band of the Cz channel were 89% and in the alpha band Pz channel 92%.
Keywords: Alzheimer's disease, image and signal processing, medial temporal atrophy, LOO Cycle.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2026214 Riemannian Manifolds for Brain Extraction on Multi-modal Resonance Magnetic Images
Authors: Mohamed Gouskir, Belaid Bouikhalene, Hicham Aissaoui, Benachir Elhadadi
Abstract:
In this paper, we present an application of Riemannian geometry for processing non-Euclidean image data. We consider the image as residing in a Riemannian manifold, for developing a new method to brain edge detection and brain extraction. Automating this process is a challenge due to the high diversity in appearance brain tissue, among different patients and sequences. The main contribution, in this paper, is the use of an edge-based anisotropic diffusion tensor for the segmentation task by integrating both image edge geometry and Riemannian manifold (geodesic, metric tensor) to regularize the convergence contour and extract complex anatomical structures. We check the accuracy of the segmentation results on simulated brain MRI scans of single T1-weighted, T2-weighted and Proton Density sequences. We validate our approach using two different databases: BrainWeb database, and MRI Multiple sclerosis Database (MRI MS DB). We have compared, qualitatively and quantitatively, our approach with the well-known brain extraction algorithms. We show that using a Riemannian manifolds to medical image analysis improves the efficient results to brain extraction, in real time, outperforming the results of the standard techniques.Keywords: Riemannian manifolds, Riemannian Tensor, Brain Segmentation, Non-Euclidean data, Brain Extraction.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1649213 Yawning and Cortisol as a Potential Biomarker for Early Detection of Multiple Sclerosis
Authors: Simon B. N. Thompson
Abstract:
Cortisol is essential to the regulation of the immune system and yawning is a pathological symptom of multiple sclerosis (MS). Electromyography activity (EMG) in the jaw muscles typically rises when the muscles are moved and with yawning is highly correlated with cortisol levels in healthy people. Saliva samples from 59 participants were collected at the start and after yawning, or at the end of the presentation of yawning-provoking stimuli, in the absence of a yawn, together with EMG data and questionnaire data: Hospital Anxiety and Depression Scale, Yawning Susceptibility Scale, General Health Questionnaire, demographic, health details. Exclusion criteria: chronic fatigue, diabetes, fibromyalgia, heart condition, high blood pressure, hormone replacement therapy, multiple sclerosis, stroke. Significant differences were found between the saliva cortisol samples for the yawners, t (23) = -4.263, p = 0.000, as compared with the non-yawners between rest and post-stimuli, which was nonsignificant. Significant evidence was found to support the Thompson Cortisol Hypothesis suggesting that rises in cortisol levels are associated with yawning. Further research is exploring the use of cortisol as an early diagnostic tool for MS. Ethics approval granted and professional code of conduct, confidentiality, and safety issues are approved therein.Keywords: Cortisol, Multiple Sclerosis, Yawning, Thompson’s Cortisol Hypothesis.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2355212 Automatic Music Score Recognition System Using Digital Image Processing
Authors: Yuan-Hsiang Chang, Zhong-Xian Peng, Li-Der Jeng
Abstract:
Music has always been an integral part of human’s daily lives. But, for the most people, reading musical score and turning it into melody is not easy. This study aims to develop an Automatic music score recognition system using digital image processing, which can be used to read and analyze musical score images automatically. The technical approaches included: (1) staff region segmentation; (2) image preprocessing; (3) note recognition; and (4) accidental and rest recognition. Digital image processing techniques (e.g., horizontal /vertical projections, connected component labeling, morphological processing, template matching, etc.) were applied according to musical notes, accidents, and rests in staff notations. Preliminary results showed that our system could achieve detection and recognition rates of 96.3% and 91.7%, respectively. In conclusion, we presented an effective automated musical score recognition system that could be integrated in a system with a media player to play music/songs given input images of musical score. Ultimately, this system could also be incorporated in applications for mobile devices as a learning tool, such that a music player could learn to play music/songs.
Keywords: Connected component labeling, image processing, morphological processing, optical musical recognition.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1914211 Design and Implementation a Fully Autonomous Soccer Player Robot
Authors: S. H. Mohades Kasaei, S. M. Mohades Kasaei, S. A. Mohades Kasaei, M. Taheri, M. Rahimi, H. Vahiddastgerdi, M. Saeidinezhad
Abstract:
Omni directional mobile robots have been popularly employed in several applications especially in soccer player robots considered in Robocup competitions. However, Omni directional navigation system, Omni-vision system and solenoid kicking mechanism in such mobile robots have not ever been combined. This situation brings the idea of a robot with no head direction into existence, a comprehensive Omni directional mobile robot. Such a robot can respond more quickly and it would be capable for more sophisticated behaviors with multi-sensor data fusion algorithm for global localization base on the data fusion. This paper has tried to focus on the research improvements in the mechanical, electrical and software design of the robots of team ADRO Iran. The main improvements are the world model, the new strategy framework, mechanical structure, Omni-vision sensor for object detection, robot path planning, active ball handling mechanism and the new kicker design, , and other subjects related to mobile robotKeywords: Mobile robot, Machine vision, Omni directional movement, Autonomous Systems, Robot path planning, Object Localization.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2136210 Identification of Disease Causing DNA Motifs in Human DNA Using Clustering Approach
Authors: G. Tamilpavai, C. Vishnuppriya
Abstract:
Studying DNA (deoxyribonucleic acid) sequence is useful in biological processes and it is applied in the fields such as diagnostic and forensic research. DNA is the hereditary information in human and almost all other organisms. It is passed to their generations. Earlier stage detection of defective DNA sequence may lead to many developments in the field of Bioinformatics. Nowadays various tedious techniques are used to identify defective DNA. The proposed work is to analyze and identify the cancer-causing DNA motif in a given sequence. Initially the human DNA sequence is separated as k-mers using k-mer separation rule. The separated k-mers are clustered using Self Organizing Map (SOM). Using Levenshtein distance measure, cancer associated DNA motif is identified from the k-mer clusters. Experimental results of this work indicate the presence or absence of cancer causing DNA motif. If the cancer associated DNA motif is found in DNA, it is declared as the cancer disease causing DNA sequence. Otherwise the input human DNA is declared as normal sequence. Finally, elapsed time is calculated for finding the presence of cancer causing DNA motif using clustering formation. It is compared with normal process of finding cancer causing DNA motif. Locating cancer associated motif is easier in cluster formation process than the other one. The proposed work will be an initiative aid for finding genetic disease related research.
Keywords: Bioinformatics, cancer motif, DNA, k-mers, Levenshtein distance, SOM.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1350209 The Onset of Ironing during Casing Expansion
Authors: W. Assaad, D. Wilmink, H. R. Pasaribu, H. J. M. Geijselaers
Abstract:
Shell has developed a mono-diameter well concept for oil and gas wells as opposed to the traditional telescopic well design. A Mono-diameter well design allows well to have a single inner diameter from the surface all the way down to reservoir to increase production capacity, reduce material cost and reduce environmental footprint. This is achieved by expansion of liners (casing string) concerned using an expansion tool (e.g. a cone). Since the well is drilled in stages and liners are inserted to support the borehole, overlap sections between consecutive liners exist which should be expanded. At overlap, the previously inserted casing which can be expanded or unexpanded is called the host casing and the newly inserted casing is called the expandable casing. When the cone enters the overlap section, an expandable casing is expanded against a host casing, a cured cement layer and formation. In overlap expansion, ironing or lengthening may appear instead of shortening in the expandable casing when the pressure exerted by the host casing, cured cement layer and formation exceeds a certain limit. This pressure is related to cement strength, thickness of cement layer, host casing material mechanical properties, host casing thickness, formation type and formation strength. Ironing can cause implications that hinder the deployment of the technology. Therefore, the understanding of ironing becomes essential. A physical model is built in-house to calculate expansion forces, stresses, strains and post expansion casing dimensions under different conditions. In this study, only free casing and overlap expansion of two casings are addressed while the cement and formation will be incorporated in future study. Since the axial strain can be predicted by the physical model, the onset of ironing can be confirmed. In addition, this model helps in understanding ironing and the parameters influencing it. Finally, the physical model is validated with Finite Element (FE) simulations and small-scale experiments. The results of the study confirm that high pressure leads to ironing when the casing is expanded in tension mode.
Keywords: Casing expansion, cement, formation, metal forming, plasticity, well design.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 761208 Medical Knowledge Management in Healthcare Industry
Authors: B. Stroetmann, A. Aisenbrey
Abstract:
The Siemens Healthcare Sector is one of the world's largest suppliers to the healthcare industry and a trendsetter in medical imaging and therapy, laboratory diagnostics, medical information technology, and hearing aids. Siemens offers its customers products and solutions for the entire range of patient care from a single source – from prevention and early detection to diagnosis, and on to treatment and aftercare. By optimizing clinical workflows for the most common diseases, Siemens also makes healthcare faster, better, and more cost effective. The optimization of clinical workflows requires a multidisciplinary focus and a collaborative approach of e.g. medical advisors, researchers and scientists as well as healthcare economists. This new form of collaboration brings together experts with deep technical experience, physicians with specialized medical knowledge as well as people with comprehensive knowledge about health economics. As Charles Darwin is often quoted as saying, “It is neither the strongest of the species that survive, nor the most intelligent, but the one most responsive to change," We believe that those who can successfully manage this change will emerge as winners, with valuable competitive advantage. Current medical information and knowledge are some of the core assets in the healthcare industry. The main issue is to connect knowledge holders and knowledge recipients from various disciplines efficiently in order to spread and distribute knowledge.Keywords: Business Excellence, Clinical Knowledge, Knowledge Management, Knowledge Services, Learning Organizations, Trust.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3144207 A Robust Diverged Localization and Recognition of License Registration Characters
Authors: M. Sankari, R. Bremananth, C.Meena
Abstract:
Localization and Recognition of License registration characters from the moving vehicle is a computationally complex task in the field of machine vision and is of substantial interest because of its diverse applications such as cross border security, law enforcement and various other intelligent transportation applications. Previous research used the plate specific details such as aspect ratio, character style, color or dimensions of the plate in the complex task of plate localization. In this paper, license registration character is localized by Enhanced Weight based density map (EWBDM) method, which is independent of such constraints. In connection with our previous method, this paper proposes a method that relaxes constraints in lighting conditions, different fonts of character occurred in the plate and plates with hand-drawn characters in various aspect quotients. The robustness of this method is well suited for applications where the appearance of plates seems to be varied widely. Experimental results show that this approach is suited for recognizing license plates in different external environments.
Keywords: Character segmentation, Connectivity checking, Edge detection, Image analysis, license plate localization, license number recognition, Quality frame selection
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1876206 Optimization of Thermopile Sensor Performance of Polycrystalline Silicon Film
Authors: Li Long, Thomas Ortlepp
Abstract:
A theoretical model for the optimization of thermopile sensor performance is developed for thermoelectric-based infrared radiation detection. It is shown that the performance of polycrystalline silicon film thermopile sensor can be optimized according to the thermoelectric quality factor, sensor layer structure factor and sensor layout shape factor. Based on the properties of electrons, phonons, grain boundaries and their interactions, the thermoelectric quality factor of polycrystalline silicon is analyzed with the relaxation time approximation of Boltzmann transport equation. The model includes the effects of grain structure, grain boundary trap properties and doping concentration. The layer structure factor of sensor is analyzed with respect to infrared absorption coefficient. The effect of layout design is characterized with the shape factor, which is calculated for different sensor designs. Double layer polycrystalline silicon thermopile infrared sensors on suspended support membrane have been designed and fabricated with a CMOS-compatible process. The theoretical approach is confirmed with measurement results.
Keywords: Polycrystalline silicon film, relaxation time approximation, specific detectivity, thermal conductivity, thermopile infrared sensor.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 201205 Harnessing the Power of AI: Transforming DevSecOps for Enhanced Cloud Security
Authors: Ashly Joseph, Jithu Paulose
Abstract:
The increased usage of cloud computing has revolutionized the IT landscape, but it has also raised new security concerns. DevSecOps emerged as a way for tackling these difficulties by integrating security into the software development process. However, the rising complexity and sophistication of cyber threats need more advanced solutions. This paper looks into the usage of artificial intelligence (AI) techniques in the DevSecOps framework to increase cloud security. This study uses quantitative and qualitative techniques to assess the usefulness of AI approaches such as machine learning, natural language processing, and deep learning in reducing security issues. This paper thoroughly examines the symbiotic relationship between AI and DevSecOps, concentrating on how AI may be seamlessly integrated into the continuous integration and continuous delivery (CI/CD) pipeline, automated security testing, and real-time monitoring methods. The findings emphasize AI's huge potential to improve threat detection, risk assessment, and incident response skills. Furthermore, the paper examines the implications and challenges of using AI in DevSecOps workflows, considering factors like as scalability, interpretability, and adaptability. This paper adds to a better understanding of AI's revolutionary role in cloud security and provides valuable insights for practitioners and scholars in the field.
Keywords: Cloud Security, DevSecOps, Artificial Intelligence, AI, Machine Learning, Natural Language Processing, NLP, cybersecurity, AI-driven Security.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 75204 Analysis of Reflectance Photoplethysmograph Sensors
Authors: Fu-Hsuan Huang, Po-Jung Yuan, Kang-Ping Lin, Hen-Hong Chang, Cheng-Lun Tsai
Abstract:
Photoplethysmography is a simple measurement of the variation in blood volume in tissue. It detects the pulse signal of heart beat as well as the low frequency signal of vasoconstriction and vasodilation. The transmission type measurement is limited to only a few specific positions for example the index finger that have a short path length for light. The reflectance type measurement can be conveniently applied on most parts of the body surface. This study analyzed the factors that determine the quality of reflectance photoplethysmograph signal including the emitter-detector distance, wavelength, light intensity, and optical properties of skin tissue. Light emitting diodes (LEDs) with four different visible wavelengths were used as the light emitters. A phototransistor was used as the light detector. A micro translation stage adjusts the emitter-detector distance from 2 mm to 15 mm. The reflective photoplethysmograph signals were measured on different sites. The optimal emitter-detector distance was chosen to have a large dynamic range for low frequency drifting without signal saturation and a high perfusion index. Among these four wavelengths, a yellowish green (571nm) light with a proper emitter-detection distance of 2mm is the most suitable for obtaining a steady and reliable reflectance photoplethysmograph signalKeywords: Reflectance photoplethysmograph, Perfusion index, Signal-to-noise ratio
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2182203 Recognition Machine (RM) for On-line and Isolated Flight Deck Officer (FDO) Gestures
Authors: Deniz T. Sodiri, Venkat V S S Sastry
Abstract:
The paper presents an on-line recognition machine (RM) for continuous/isolated, dynamic and static gestures that arise in Flight Deck Officer (FDO) training. RM is based on generic pattern recognition framework. Gestures are represented as templates using summary statistics. The proposed recognition algorithm exploits temporal and spatial characteristics of gestures via dynamic programming and Markovian process. The algorithm predicts corresponding index of incremental input data in the templates in an on-line mode. Accumulated consistency in the sequence of prediction provides a similarity measurement (Score) between input data and the templates. The algorithm provides an intuitive mechanism for automatic detection of start/end frames of continuous gestures. In the present paper, we consider isolated gestures. The performance of RM is evaluated using four datasets - artificial (W TTest), hand motion (Yang) and FDO (tracker, vision-based ). RM achieves comparable results which are in agreement with other on-line and off-line algorithms such as hidden Markov model (HMM) and dynamic time warping (DTW). The proposed algorithm has the additional advantage of providing timely feedback for training purposes.Keywords: On-line Recognition Algorithm, IsolatedDynamic/Static Gesture Recognition, On-line Markovian/DynamicProgramming, Training in Virtual Environments.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1449202 In Search of an SVD and QRcp Based Optimization Technique of ANN for Automatic Classification of Abnormal Heart Sounds
Authors: Samit Ari, Goutam Saha
Abstract:
Artificial Neural Network (ANN) has been extensively used for classification of heart sounds for its discriminative training ability and easy implementation. However, it suffers from overparameterization if the number of nodes is not chosen properly. In such cases, when the dataset has redundancy within it, ANN is trained along with this redundant information that results in poor validation. Also a larger network means more computational expense resulting more hardware and time related cost. Therefore, an optimum design of neural network is needed towards real-time detection of pathological patterns, if any from heart sound signal. The aims of this work are to (i) select a set of input features that are effective for identification of heart sound signals and (ii) make certain optimum selection of nodes in the hidden layer for a more effective ANN structure. Here, we present an optimization technique that involves Singular Value Decomposition (SVD) and QR factorization with column pivoting (QRcp) methodology to optimize empirically chosen over-parameterized ANN structure. Input nodes present in ANN structure is optimized by SVD followed by QRcp while only SVD is required to prune undesirable hidden nodes. The result is presented for classifying 12 common pathological cases and normal heart sound.Keywords: ANN, Classification of heart diseases, murmurs, optimization, Phonocardiogram, QRcp, SVD.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2055201 Researches on Simulation and Validation of Airborne Enhanced Ground Proximity Warning System
Authors: Ma Shidong, He Yuncheng, Wang Zhong, Yang Guoqing
Abstract:
In this paper, enhanced ground proximity warning simulation and validation system is designed and implemented. First, based on square grid and sub-grid structure, the global digital terrain database is designed and constructed. Terrain data searching is implemented through querying the latitude and longitude bands and separated zones of global terrain database with the current aircraft position. A combination of dynamic scheduling and hierarchical scheduling is adopted to schedule the terrain data, and the terrain data can be read and delete dynamically in the memory. Secondly, according to the scope, distance, approach speed information etc. to the dangerous terrain in front, and using security profiles calculating method, collision threat detection is executed in real-time, and provides caution and warning alarm. According to this scheme, the implementation of the enhanced ground proximity warning simulation system is realized. Simulations are carried out to verify a good real-time in terrain display and alarm trigger, and the results show simulation system is realized correctly, reasonably and stable.
Keywords: enhanced ground proximity warning system, digital terrain, look-ahead terrain alarm, terrain display, simulation and validation
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1681200 The Comparation of Activation Nuclear Factor Kappa Beta (NFKB) at Rattus Novergicus Strain Wistar Induced by Various Duration High Fat Diet (HFD)
Authors: Titin Andri Wihastuti, Djanggan Sargowo
Abstract:
NFκB is a transcription factor regulating many function of the vessel wall. In the normal condition , NFκB is revealed diffuse cytoplasmic expressionsuggesting that the system is inactive. The presence of activation NFκB provide a potential pathway for the rapid transcriptional of a variety of genes encoding cytokines, growth factors, adhesion molecules and procoagulatory factors. It is likely to play an important role in chronic inflamatory disease involved atherosclerosis. There are many stimuli with the potential to active NFκB, including hyperlipidemia. We used 24 mice which was divided in 6 groups. The HFD given by et libitum procedure during 2, 4, and 6 months. The parameters in this study were the amount of NFKB activation ,H2O2 as ROS and VCAM-1 as a product of NFKB activation. H2O2 colorimetryc assay performed directly using Anti Rat H2O2 ELISA Kit. The NFKB and VCAM-1 detection obtained from aorta mice, measured by ELISA kit and imunohistochemistry. There was a significant difference activation of H2O2, NFKB and VCAM-1 level at induce HFD after 2, 4 and 6 months. It suggest that HFD induce ROS formation and increase the activation of NFKB as one of atherosclerosis marker that caused by hyperlipidemia as classical atheroschlerosis risk factor.Keywords: High Fat Diet, NFKB, H2O2, atherosclerosis
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2023199 Urban Land Cover Change of Olomouc City Using LANDSAT Images
Authors: Miloš Marjanović, Jaroslav Burian, Ja kub Miřijovský, Jan Harbula
Abstract:
This paper regards the phenomena of intensive suburbanization and urbanization in Olomouc city and in Olomouc region in general for the period of 1986–2009. A Remote Sensing approach that involves tracking of changes in Land Cover units is proposed to quantify the urbanization state and trends in temporal and spatial aspects. It actually consisted of two approaches, Experiment 1 and Experiment 2 which implied two different image classification solutions in order to provide Land Cover maps for each 1986–2009 time split available in the Landsat image set. Experiment 1 dealt with the unsupervised classification, while Experiment 2 involved semi- supervised classification, using a combination of object-based and pixel-based classifiers. The resulting Land Cover maps were subsequently quantified for the proportion of urban area unit and its trend through time, and also for the urban area unit stability, yielding the relation of spatial and temporal development of the urban area unit. Some outcomes seem promising but there is indisputably room for improvements of source data and also processing and filtering.
Keywords: Change detection, image classification, land cover, Landsat images, Olomouc city, urbanization.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1813