Search results for: quality control tools.
1052 Performance Analysis of CATR Reflector with Super Hybrid Modulated Segmented Exponential Serrated Edges
Authors: T. Venkata Rama Krishna, P. Siddaiah, B. Prabhakara Rao
Abstract:
This paper presented a theoretical and numerical investigation of the Compact Antenna Test Range (CATR) equipped with Super Hybrid Modulated Segmented Exponential Serrations (SHMSES). The investigation was based on diffraction theory and, more specifically, the Fresnel diffraction formulation. The CATR provides uniform illumination within the Fresnel region to test antenna. Application of serrated edges has been shown to be a good method to control diffraction at the edges of the reflectors. However, in order to get some insight into the positive effect of serrated edges a less rigorous analysis technique known as Physical Optics (PO) may be used. Ripple free and enhanced quiet zone width are observed for specific values of width and height modulation factors per serrations. The performance of SHMSE serrated reflector is evaluated in order to observe the effects of edge diffraction on the test zone fields.
Keywords: Fresnel region, quiet zone, physical optics, ripples, serrations.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 15381051 A Holistic Conceptual Measurement Framework for Assessing the Effectiveness and Viability of an Academic Program
Authors: Munir Majdalawieh, Adam Marks
Abstract:
In today’s very competitive higher education industry (HEI), HEIs are faced with the primary concern of developing, deploying, and sustaining high quality academic programs. Today, the HEI has well-established accreditation systems endorsed by a country’s legislation and institutions. The accreditation system is an educational pathway focused on the criteria and processes for evaluating educational programs. Although many aspects of the accreditation process highlight both the past and the present (prove), the “program review” assessment is "forward-looking assessment" (improve) and thus transforms the process into a continuing assessment activity rather than a periodic event. The purpose of this study is to propose a conceptual measurement framework for program review to be used by HEIs to undertake a robust and targeted approach to proactively and continuously review their academic programs to evaluate its practicality and effectiveness as well as to improve the education of the students. The proposed framework consists of two main components: program review principles and the program review measurement matrix.Keywords: Academic program, program review principles, curriculum development, accreditation, evaluation, assessment, review measurement matrix, program review process, information technologies supporting learning, learning/teaching methodologies and assessment.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 10911050 A Neural Network Classifier for Estimation of the Degree of Infestation by Late Blight on Tomato Leaves
Authors: Gizelle K. Vianna, Gabriel V. Cunha, Gustavo S. Oliveira
Abstract:
Foliage diseases in plants can cause a reduction in both quality and quantity of agricultural production. Intelligent detection of plant diseases is an essential research topic as it may help monitoring large fields of crops by automatically detecting the symptoms of foliage diseases. This work investigates ways to recognize the late blight disease from the analysis of tomato digital images, collected directly from the field. A pair of multilayer perceptron neural network analyzes the digital images, using data from both RGB and HSL color models, and classifies each image pixel. One neural network is responsible for the identification of healthy regions of the tomato leaf, while the other identifies the injured regions. The outputs of both networks are combined to generate the final classification of each pixel from the image and the pixel classes are used to repaint the original tomato images by using a color representation that highlights the injuries on the plant. The new images will have only green, red or black pixels, if they came from healthy or injured portions of the leaf, or from the background of the image, respectively. The system presented an accuracy of 97% in detection and estimation of the level of damage on the tomato leaves caused by late blight.
Keywords: Artificial neural networks, digital image processing, pattern recognition.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 25571049 Neural Network Control of a Biped Robot Model with Composite Adaptation Low
Authors: Ahmad Forouzantabar
Abstract:
this paper presents a novel neural network controller with composite adaptation low to improve the trajectory tracking problems of biped robots comparing with classical controller. The biped model has 5_link and 6 degrees of freedom and actuated by Plated Pneumatic Artificial Muscle, which have a very high power to weight ratio and it has large stoke compared to similar actuators. The proposed controller employ a stable neural network in to approximate unknown nonlinear functions in the robot dynamics, thereby overcoming some limitation of conventional controllers such as PD or adaptive controllers and guarantee good performance. This NN controller significantly improve the accuracy requirements by retraining the basic PD/PID loop, but adding an inner adaptive loop that allows the controller to learn unknown parameters such as friction coefficient, therefore improving tracking accuracy. Simulation results plus graphical simulation in virtual reality show that NN controller tracking performance is considerably better than PD controller tracking performance.Keywords: Biped robot, Neural network, Plated Pneumatic Artificial Muscle, Composite adaptation
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 18501048 Increase of Organization in Complex Systems
Authors: Georgi Yordanov Georgiev, Michael Daly, Erin Gombos, Amrit Vinod, Gajinder Hoonjan
Abstract:
Measures of complexity and entropy have not converged to a single quantitative description of levels of organization of complex systems. The need for such a measure is increasingly necessary in all disciplines studying complex systems. To address this problem, starting from the most fundamental principle in Physics, here a new measure for quantity of organization and rate of self-organization in complex systems based on the principle of least (stationary) action is applied to a model system - the central processing unit (CPU) of computers. The quantity of organization for several generations of CPUs shows a double exponential rate of change of organization with time. The exact functional dependence has a fine, S-shaped structure, revealing some of the mechanisms of self-organization. The principle of least action helps to explain the mechanism of increase of organization through quantity accumulation and constraint and curvature minimization with an attractor, the least average sum of actions of all elements and for all motions. This approach can help describe, quantify, measure, manage, design and predict future behavior of complex systems to achieve the highest rates of self organization to improve their quality. It can be applied to other complex systems from Physics, Chemistry, Biology, Ecology, Economics, Cities, network theory and others where complex systems are present.
Keywords: Organization, self-organization, complex system, complexification, quantitative measure, principle of least action, principle of stationary action, attractor, progressive development, acceleration, stochastic.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16421047 Heavy Metals Transport in the Soil Profiles under the Application of Sludge and Wastewater
Authors: A. Behbahaninia, S. A. Mirbagheri, A. H. Javid
Abstract:
Heavy metal transfer in soil profiles is a major environmental concern because even slow transport through the soil may eventually lead to deterioration of groundwater quality. The use of sewage sludge and effluents from wastewater treatment plants for irrigation of agricultural lands is on the rise particularly in peri-urban area of developing countries. In this study soil samples under sludge application and wastewater irrigation were studied and soil samples were collected in the soil profiles from the surface to 100 cm in depth. For this purpose, three plots were made in a treatment plant in south of Tehran-Iran. First plot was irrigated just with effluent from wastewater treatment plant, second plot with simulated heavy metals concentration equal 50 years irrigation and in third plot sewage sludge and effluent was used. Trace metals concentration (Cd, Cu) were determined for soil samples. The results indicate movement of metals was observed, but the most concentration of metals was found in topsoil samples. The most of Cadmium concentration was measured in the topsoil of plot 3, 4.5mg/kg and Maximum cadmium movement was observed in 0-20 cm. The most concentration of copper was 27.76mg/kg, and maximum percolation in 0-20 cm. Metals (Cd, Cu) were measured in leached water. Preferential flow and metal complexation with soluble organic apparently allow leaching of heavy metals.Keywords: Heavy metal, sludge, soil, transport.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 17911046 Determination of Some Agricultural Characters of Developed Pea (Pisum sativum L.) Lines
Authors: Ercan Ceyhan, Mehmet Ali Avci
Abstract:
This research was made during the 2015 growing periods in the trial filed of "Research Station for Department of Field Crops, Agricultural Faculty, Selcuk University" according to “Randomized Blocks Design” with 3 replications. Research material was the following pea lines; PS16, PS18, PS21, PS23, PS24, PS25, PS36, PS47, PS49, PS51, PS54, PS58, PS67, PS69, PS71, PS73, PS83, PS84, PS87 and PSKY and three cultivars and other 2 commercial varieties named as Bolero, Rondo and Ultrello. Some agronomical characteristics such as plant height (cm) number of pod per plant number of seed per pod number of seed per plant 100 seed weight (g) and seed yield (kg ha-1) were determined. The highest seed yield was obtained 2727.0 kg ha-1 in the PS71 line and the lowest value was obtained 1238.0 kg ha-1 in the commercial variety of Bolero. Results of the research implicated that the new developed lines were superior compared with the control (commercial) varieties by means of most of the characteristics. Nevertheless, similar researches should be continued in different locations and years.Keywords: Agricultural characters, pea, Pisum sativum, seed yield.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 21341045 Effects of Gamma Radiation on Tomato Leafminer, Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae)
Authors: Akın Kuyulu, Hanife Genç
Abstract:
In present study, it was aimed to evaluate the gamma radiation impacts on tomato leaf miner at different biological stages. The laboratory colony of tomato leaf miner was used to set up the experiments. Different biological stages of the insects (eggs, 4th instars and pupae) were irradiated using Cobalt-60 at doses of 0 (control), 100 Gray (Gy), 200 Gy, 300 Gy and 400 Gy in Cos-44HH-N source, at dose rate of 480 Gy/h. After irradiation, the eggs were incubated until hatching; the mature larvae were reared to complete their developments. Adult emergences from irradiated pupae were also evaluated. The results showed that there were no egg hatching at all tested irradiation doses. Although, the pupal percentages of irradiated mature larvae were 54%, 15% and 8% at doses of 100 Gy, 200 Gy and 300 Gy respectively, there were no adult emergences from irradiated mature larvae. On the other hand, the adult emergences were observed from irradiated pupae, decreased as radiation doses increased along with malformed adult appearance. Male and female individuals were out crossed with laboratory reared adults. Fecundity was correlated with radiation doses.Keywords: Irradiation, tomato, tomato leafminer, Tuta absoluta.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 15881044 Production of IAA by Bradyrhizobium sp.
Authors: Nisa Rachmania Mubarik, Irni Mahagiani, Aris Tri Wahyudi
Abstract:
The objective of this research was to determine the potency of indigenous acid-aluminium tolerant Bradyrhizobium japonicum as producer of indole acetic acid (IAA) and applied it as nitrogen fixation on local soybeans viz Anjasmoro, Tanggamus (yellow soybean seeds), and Detam (black soybean seed). Three isolates of acid-aluminium tolerant Bradyrhizobium japonicum (BJ) were used in this research, i.e. BJ 11 (wt), BJ 11 (19) - BJ 11(wt) mutant, and USDA 110 as a reference isolate. All of isolates tested to produce the IAA by using Salkowsky method. Effect of IAA production by each of B. japonicum was tested on growth pouch and greenhouse using three varieties of soybean. All isolates could grow well and produce IAA on yeast mannitol broth (YMB) medium in the presence of 0.5 mM L-tryptophan. BJ 11 (19) produced the highest of IAA at 4 days incubation compared to BJ 11 (wt) and USDA 110. All tested isolates of Bradyrhizobium japonicum have showed effect on stimulating the formation of root nodules in soybean varieties grown on Leonard bottle. The concentration of IAA on root nodules of soybean symbiotic with B. japonicum was significantly different with control, except on the treatment using Tanggamus soybean.Keywords: Acid-aluminium tolerant isolate, Bradyrhizobium japonicum, indole acetic acid, soybean.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20261043 Investigating the Dynamic Response of the Ballast
Authors: Osama Brinji, Wing Kong Chiu, Graham Tew
Abstract:
Understanding the stability of rail ballast is one of the most important aspects in the railways. An unstable track may cause some issues such as unnecessary vibration and ultimately loss of track quality. The track foundation plays an important role in the stabilization of the railway. The dynamic response of rail ballast in the vicinity of the rail sleeper can affect the stability of the rail track and this has not been studied in detail. A review of literature showed that most of the works focused on the area under the concrete sleeper. Although there are some theories about the shear (longitudinal) effect of the rail ballast, these have not properly been studied and hence are not well understood. The stability of a rail track will depend on the compactness of the ballast in its vicinity. This paper will try to determine the dynamic response of the ballast to identify its resonant behaviour. This preliminary research is one of several studies that examine the vibration response of the granular materials. The main aim is to use this information for future design of sleepers to ensure that any dynamic response of the sleeper will not compromise the state of compactness of the ballast. This paper will report on the dependence of damping and the natural frequency of the ballast as a function of depth and distance from the point of excitation introduced through a concrete block. The concrete block is used to simulate a sleeper and the ballast is simulated with gravel. In spite of these approximations, the results presented in the paper will show an agreement with theories and the assumptions that are used in study the mechanical behaviour of the rail ballast.
Keywords: Ballast, dynamic response, sleeper, stability.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16531042 Adaptive Kaman Filter for Fault Diagnosis of Linear Parameter-Varying Systems
Authors: Rajamani Doraiswami, Lahouari Cheded
Abstract:
Fault diagnosis of Linear Parameter-Varying (LPV) system using an adaptive Kalman filter is proposed. The LPV model is comprised of scheduling parameters, and the emulator parameters. The scheduling parameters are chosen such that they are capable of tracking variations in the system model as a result of changes in the operating regimes. The emulator parameters, on the other hand, simulate variations in the subsystems during the identification phase and have negligible effect during the operational phase. The nominal model and the influence vectors, which are the gradient of the feature vector respect to the emulator parameters, are identified off-line from a number of emulator parameter perturbed experiments. A Kalman filter is designed using the identified nominal model. As the system varies, the Kalman filter model is adapted using the scheduling variables. The residual is employed for fault diagnosis. The proposed scheme is successfully evaluated on simulated system as well as on a physical process control system.Keywords: Keywords—Identification, linear parameter-varying systems, least-squares estimation, fault diagnosis, Kalman filter, emulators
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 13031041 A New Approach for Image Segmentation using Pillar-Kmeans Algorithm
Authors: Ali Ridho Barakbah, Yasushi Kiyoki
Abstract:
This paper presents a new approach for image segmentation by applying Pillar-Kmeans algorithm. This segmentation process includes a new mechanism for clustering the elements of high-resolution images in order to improve precision and reduce computation time. The system applies K-means clustering to the image segmentation after optimized by Pillar Algorithm. The Pillar algorithm considers the pillars- placement which should be located as far as possible from each other to withstand against the pressure distribution of a roof, as identical to the number of centroids amongst the data distribution. This algorithm is able to optimize the K-means clustering for image segmentation in aspects of precision and computation time. It designates the initial centroids- positions by calculating the accumulated distance metric between each data point and all previous centroids, and then selects data points which have the maximum distance as new initial centroids. This algorithm distributes all initial centroids according to the maximum accumulated distance metric. This paper evaluates the proposed approach for image segmentation by comparing with K-means and Gaussian Mixture Model algorithm and involving RGB, HSV, HSL and CIELAB color spaces. The experimental results clarify the effectiveness of our approach to improve the segmentation quality in aspects of precision and computational time.Keywords: Image segmentation, K-means clustering, Pillaralgorithm, color spaces.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 33751040 Closing the Achievement Gap Within Reading and Mathematics Classrooms by Fostering Hispanic Students- Educational Resilience
Authors: Hersh C. Waxman, Yolanda N. Padrón, Jee-Young Shin, Héctor H. Rivera
Abstract:
While many studies have conducted the achievement gap between groups of students in school districts, few studies have utilized resilience research to investigate achievement gaps within classrooms. This paper aims to summarize and discuss some recent studies Waxman, Padr├│n, and their colleagues conducted, in which they examined learning environment differences between resilient and nonresilient students in reading and mathematics classrooms. The classes consist of predominantly Hispanic elementary school students from low-income families. These studies all incorporated learning environment questionnaires and systematic observation methods. Significant differences were found between resilient and nonresilient students on their classroom learning environments and classroom behaviors. The observation results indicate that the amount and quality of teacher and student academic interaction are two of the most influential variables that promote student outcomes. This paper concludes by suggesting the following teacher practices to promote resiliency in schools: (a) using feedback from classroom observation and learning environment measures, (b) employing explicit teaching practices; and (c) understanding students on a social and personal level.Keywords: achievement gap, classroom learning environments, educational resilience, systematic classroom observation
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19881039 Platform-as-a-Service Sticky Policies for Privacy Classification in the Cloud
Authors: Maha Shamseddine, Amjad Nusayr, Wassim Itani
Abstract:
In this paper, we present a Platform-as-a-Service (PaaS) model for controlling the privacy enforcement mechanisms applied on user data when stored and processed in Cloud data centers. The proposed architecture consists of establishing user configurable ‘sticky’ policies on the Graphical User Interface (GUI) data-bound components during the application development phase to specify the details of privacy enforcement on the contents of these components. Various privacy classification classes on the data components are formally defined to give the user full control on the degree and scope of privacy enforcement including the type of execution containers to process the data in the Cloud. This not only enhances the privacy-awareness of the developed Cloud services, but also results in major savings in performance and energy efficiency due to the fact that the privacy mechanisms are solely applied on sensitive data units and not on all the user content. The proposed design is implemented in a real PaaS cloud computing environment on the Microsoft Azure platform.Keywords: Privacy enforcement, Platform-as-a-Service privacy awareness, cloud computing privacy.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 7651038 Evaluation of Thrombolytic Activity of Zingiber cassumunar Roxb. and Thai Herbal Prasaplai Formula
Authors: Warachate Khobjai, Suriyan Sukati, Khemjira Jarmkom, Pattaranut Eakwaropas, Surachai Techaoei
Abstract:
The propose of this study was to investigate in vitro thrombolytic activity of Zingiber cassumunar Roxb. and Prasaplai, a Thai herbal formulation of Z. cassumunar Roxb. Herbs were extracted with boiling water and concentrated by lyophilization. To observe their thrombolytic potential, an in vitro clot lysis method was applied where streptokinase and sterile distilled water were used as positive and negative controls, respectively. Crude aqueous extracts from Z. cassumunar Roxb. and Prasaplai formula showed significant thrombolytic activity by clot lysis of 17.90% and 25.21%, respectively, compared to the negative control water (5.16%) while the standard streptokinase revealed 64.78% clot lysis. These findings suggest that Z. cassumunar Roxb. exhibits moderate thrombolytic activity and cloud play an important role in the thrombolytic properties of Prasaplai formula. However, further study should be done to observe in vivo clot dissolving potential and to isolate active component(s) of these extracts.
Keywords: Aqueous extract, prasaplai formula, thrombolytic activity, Zingiber cassumunar Roxb.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 14151037 Solar Energy Generation Based Urban Development: A Case of Jodhpur City
Authors: A. Kumar, V. Devadas
Abstract:
India has the most year-round favorable sunny conditions along with the second-highest solar irradiation in the world, the country holds the potential to become the global solar hub. The solar and wind-based generation capacity has skyrocketed in India with the successful effort of the Ministry of Renewable Energy, whereas the potential of rooftop based solar power generation has yet to be explored for proposed solar cities in India. The research aims to analyze the gap in the energy scenario in Jodhpur City and proposes interventions of solar energy generation systems as a catalyst for urban development. The research is based on the system concept which deals with simulation between the city system as a whole and its interactions between different subsystems. A system-dynamics based mathematical model is developed by identifying the control parameters using regression and correlation analysis to assess the gap in energy sector. The base model validation is done using the past 10 years timeline data collected from secondary sources. Further, energy consumption and solar energy generation-based projection are made for testing different scenarios to conclude the feasibility for maintaining the city level energy independence till 2031.
Keywords: City, consumption, energy, generation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 5681036 Careers-Outreach Programmes for Children: Lessons for Perceptions of Engineering and Manufacturing
Authors: Niall J. English, Sylvia Leatham, Maria Isabel Meza Silva, Denis P. Dowling
Abstract:
The training and education of under- and post-graduate students can be promoted by more active learning especially in engineering, overcoming more passive and vicarious experiences and approaches in their documented effectiveness. However, the possibility of outreach to young pupils and school-children in primary and secondary schools is a lesser explored area in terms of Education and Public Engagement (EPE) efforts – as relates to feedback and influence on shaping 3rd-level engineering training and education. Therefore, the outreach and school-visit agenda constitutes an interesting avenue to observe how active learning, careers stimulus and EPE efforts for young children and teenagers can teach the university sector, to improve future engineering-teaching standards and enhance both quality and capabilities of practice. This intervention involved careers-outreach efforts to lead to statistical determinations of motivations towards engineering, manufacturing and training. The aim was to gauge to what extent this intervention would lead to an increased careers awareness in engineering, using the method of the schools-visits programme as the means for so doing. It was found that this led to an increase in engagement by school pupils with engineering as a career option and a greater awareness of the importance of manufacturing.
Keywords: outreach, education and public engagement, careers, peer interactions
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 5101035 Experiment Study on the Influence of Tool Materials on the Drilling of Thick Stacked Plate of 2219 Aluminum Alloy
Authors: G. H. Li, M. Liu, H. J. Qi, Q. Zhu, W. Z. He
Abstract:
The drilling and riveting processes are widely used in the assembly of carrier rocket, which makes the efficiency and quality of drilling become the important factor affecting the assembly process. According to the problem existing in the drilling of thick stacked plate (thickness larger than 10mm) of carrier rocket, such as drill break, large noise and burr etc., experimental study of the influence of tool material on the drilling was carried out. The cutting force was measured by a piezoelectric dynamometer, the aperture was measured with an outline projector, and the burr is observed and measured by a digital stereo microscope. Through the measurement, the effects of tool material on the drilling were analyzed from the aspects of drilling force, diameter, and burr. The results show that, compared with carbide drill and coated carbide one, the drilling force of high speed steel is larger. But, the application of high speed steel also has some advantages, e.g. a higher number of hole can be obtained, the height of burr is small, the exit is smooth and the slim burr is less, and the tool experiences wear but not fracture. Therefore, the high speed steel tool is suitable for the drilling of thick stacked plate of 2219 Aluminum alloy.
Keywords: 2219 aluminum alloy, thick stacked plate, drilling, tool material.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 12861034 Remedying Students’ Misconceptions in Learning of Chemical Bonding and Spontaneity through Intervention Discussion Learning Model (IDLM)
Authors: Ihuarulam Ambrose Ikenna
Abstract:
In the past few decades, the field of chemistry education has grown tremendously and researches indicated that after traditional chemistry instruction students often lacked deep conceptual understanding and failed to integrate their ideas into coherent conceptual framework. For several concepts in chemistry, students at all levels have demonstrated difficulty in changing their initial perceptions. Their perceptions are most often wrong and don't agree with correct scientific concepts. This study explored the effectiveness of intervention discussion sections for a college general chemistry course designed to apply research on students preconceptions, knowledge integration and student explanation. Three interventions discussions lasting three hours on bond energy and spontaneity were done tested and intervention (treatment) students’ performances were compared with that of control group which did not use the experimental pedagogy. Results indicated that this instruction which was capable of identifying students' misconceptions, initial conceptions and integrating those ideas into class discussion led to enhanced conceptual understanding and better achievement for the experimental group.
Keywords: Intervention Discussion Learning Model, Learning, Remedying, Students’ misconceptions.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 25421033 Molecular Dynamic Simulation and Receptor-based Pharmacophore Modeling on Human Renin for Discovery of Novel Inhibitors
Authors: Chanin Park, Sundarapandian Thangapandian, Yuno Lee, Minky Son, Shalini John, Young-sik Sohn, Keun Woo Lee
Abstract:
Hypertension is characterized with stress on the heart and blood vessels thus increasing the risk of heart attack and renal diseases. The Renin angiotensin system (RAS) plays a major role in blood pressure control. Renin is the enzyme that controls the RAS at the rate-limiting step. Our aim is to develop new drug-like leads which can inhibit renin and thereby emerge as therapeutics for hypertension. To achieve this, molecular dynamics (MD) simulation and receptor-based pharmacophore modeling were implemented, and three rennin-inhibitor complex structures were selected based on IC50 value and scaffolds of inhibitors. Three pharmacophore models were generated considering conformations induced by inhibitor. The compounds mapped to these models were selected and subjected to drug-like screening. The identified hits were docked into the active site of renin. Finally, hit1 satisfying the binding mode and interaction energy was selected as possible lead candidate to be used in novel renin inhibitors.
Keywords: Renin inhibitor, Molecular dynamics simulation, Structure-based pharmacophore modeling
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19701032 Evaluation of Service Continuity in a Self-organizing IMS
Authors: Satoshi Komorita, Tsunehiko Chiba, Hidetoshi Yokota, Ashutosh Dutta, Christian Makaya, Subir Das, Dana Chee, F. Joe Lin, Henning Schulzrinne
Abstract:
The NGN (Next Generation Network), which can provide advanced multimedia services over an all-IP based network, has been the subject of much attention for years. While there have been tremendous efforts to develop its architecture and protocols, especially for IMS, which is a key technology of the NGN, it is far from being widely deployed. However, efforts to create an advanced signaling infrastructure realizing many requirements have resulted in a large number of functional components and interactions between those components. Thus, the carriers are trying to explore effective ways to deploy IMS while offering value-added services. As one such approach, we have proposed a self-organizing IMS. A self-organizing IMS enables IMS functional components and corresponding physical nodes to adapt dynamically and automatically based on situation such as network load and available system resources while continuing IMS operation. To realize this, service continuity for users is an important requirement when a reconfiguration occurs during operation. In this paper, we propose a mechanism that will provide service continuity to users and focus on the implementation and describe performance evaluation in terms of number of control signaling and processing time during reconfigurationKeywords: IMS, SIP, Service Continuity, Self-organizing, and Performance.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 15991031 Evaluation of Groundwater Unit Hydrograph of Kavar-Maharloo Aquifer
Authors: Mohammad Hosein Hojati, Fardin Boustani
Abstract:
Groundwater is one of the most important water resources in Fars province. Based on this study, 95 percent of the total annual water consumption in Fars is used for agriculture, whereas the percentages for domestic and industrial uses are 4 and 1 percent, respectively. Population growth, urban and industrial growth, and agricultural development in Fars have created a condition of water stress. In this province, farmers and other users are pumping groundwater faster than its natural replenishment rate, causing a continuous drop in groundwater tables and depletion of this resource. In this research variation of groundwater level, their effects and ways to help control groundwater levels in aquifer of the Kavar- Maharloo plains in Fars plain were evaluated .Excessive exploitation of groundwater in this aquifer caused the groundwater levels fall too fast or to unacceptable levels. The average drawdown of the groundwater level in this plain were 17 meters during 1995 to 2006. The purpose of this study is to evaluate water level changes in the Kavar-Maharloo Aquifer in the Fars province in order to determine the areas of greatest depletion, the cause of depletion, and predict the remaining life of the aquifer.Keywords: Aquifer , ground water depletion, water table
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16841030 Deicing and Corrosive Performances of Calcium Acetate Deicer Made from Bamboo-Vinegar
Authors: Xinyuan Jiang, Genan Li, Zhiping Wu
Abstract:
Calcium magnesium acetate (CMA) is environmentally benign deicing chemicals that can replace sodium chloride that is widely used on roads and highways at present for snow and ice control to provide safe driving conditions during winter. The price of CMA from petroleum-derived acetic acid is quite expensive. The bamboo vinegar is the by-product from bamboo charcoal production. The bamboo vinegar was used to prepare calcium acetate as raw materials, and its deicing and corrosive performances were studied in this paper. The results show that the freezing temperature of calcium acetate is lower than that of sodium chloride when they have same molar concentration, the deicing performance of calcium acetate is better than that of sodium chloride when they have same moles, while the deicing performance of sodium chloride is better than that of calcium acetate. The corrosion of sodium chloride on iron-nail and steel-nail is larger than that of calcium acetate whether they have same mass concentration or same molar concentration, and the corrosion of sodium chloride and calcium acetate on iron-nail is larger than that on steel-nail, and calcium acetate almost hasn't corrosion on steel-nail.Keywords: bamboo vinegar, calcium acetate, corrosion, deicer, deicing performance
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 25621029 Effect of Tube Materials and Special Coating on Coke Deposition in the Steam Cracking of Hydrocarbons
Authors: A. Niaei, D. Salari , N. Daneshvar, A. Chamandeh, R. Nabavi
Abstract:
The steam cracking reactions are always accompanied with the formation of coke which deposits on the walls of the tubular reactors. The investigation has attempted to control catalytic coking by the applying aluminum, zinc and ceramic coating like aluminum-magnesium by thermal spray and pack cementation method. Rate of coke formation during steam cracking of naphtha has been investigated both for uncoated stainless steel (with different alloys) and metal coating constructed with thermal Spray and pack cementation method with metal powders of Aluminum, Aluminum-Magnesium, zinc, silicon, nickel and chromium. The results of the study show that passivating the surface of SS321 with a coating of Aluminum and Aluminum-Magnesium can significantly reduce the rate of coke deposition during naphtha pyrolysis. SEM and EDAX techniques (Philips XL Series) were used to examine the coke deposits formed by the metal-hydrocarbon reactions. Our objective was to separate the different stages by identifying the characteristic morphologies.Keywords: Steam Cracking, Pyrolysis, Coke deposition, thermalspray, Pack Cementation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 30151028 Influence of Place Identity on Walkability: A Comparative Study between Two Mixed Used Streets Chaharbagh St. Isfahan, Iran and Dereboyu St. Lefkosa, North Cyprus
Authors: R. Rafiemanzelat
Abstract:
One of the most recent fields of investigation in urban issues focuses on the walkability in urban spaces. Considering the importance of walkability apart from pedestrian transportation, increasing walkability will help to reduce the congestion and environmental impact. This subject also matters as it has a social life, experiential quality and economical sustainability value. This study focused on the effects of walkability and place identity on each other in urban public spaces, streets in particular, as a major indicator of their success. The theoretical aspects which examine for this purpose consist of two parts: The first will evaluate the essential components of place identity in the streets and the second one will discuss the concept of walkability and its development theories which have been derived from walkable spaces. Finally, research investigates place identity and walkability and their determinants in two major streets in different cities. The streets are Chaharbagh Street in Isfahan/Iran and Dereboyu Street in Lefkosa/North Cyprus. This study has a qualitative approach with the research method of walkability studies. The qualitative method is combined with the collection of data relating to walking behavior and place identity through an observational field study. The result will show a relationship between pedestrian-friendly spaces and identity by related variables which has obtained.
Keywords: Place identity, walkability, urban public space, streets, pedestrian-friendly.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 9851027 O-Functionalized CNT Mediated CO Hydro-Deoxygenation and Chain Growth
Authors: K. Mondal, S. Talapatra, M. Terrones, S. Pokhrel, C. Frizzel, B. Sumpter, V. Meunier, A. L. Elias
Abstract:
Worldwide energy independence is reliant on the ability to leverage locally available resources for fuel production. Recently, syngas produced through gasification of carbonaceous materials provided a gateway to a host of processes for the production of various chemicals including transportation fuels. The basis of the production of gasoline and diesel-like fuels is the Fischer Tropsch Synthesis (FTS) process: A catalyzed chemical reaction that converts a mixture of carbon monoxide (CO) and hydrogen (H2) into long chain hydrocarbons. Until now, it has been argued that only transition metal catalysts (usually Co or Fe) are active toward the CO hydrogenation and subsequent chain growth in the presence of hydrogen. In this paper, we demonstrate that carbon nanotube (CNT) surfaces are also capable of hydro-deoxygenating CO and producing long chain hydrocarbons similar to that obtained through the FTS but with orders of magnitude higher conversion efficiencies than the present state-of-the-art FTS catalysts. We have used advanced experimental tools such as XPS and microscopy techniques to characterize CNTs and identify C-O functional groups as the active sites for the enhanced catalytic activity. Furthermore, we have conducted quantum Density Functional Theory (DFT) calculations to confirm that C-O groups (inherent on CNT surfaces) could indeed be catalytically active towards reduction of CO with H2, and capable of sustaining chain growth. The DFT calculations have shown that the kinetically and thermodynamically feasible route for CO insertion and hydro-deoxygenation are different from that on transition metal catalysts. Experiments on a continuous flow tubular reactor with various nearly metal-free CNTs have been carried out and the products have been analyzed. CNTs functionalized by various methods were evaluated under different conditions. Reactor tests revealed that the hydrogen pre-treatment reduced the activity of the catalysts to negligible levels. Without the pretreatment, the activity for CO conversion as found to be 7 µmol CO/g CNT/s. The O-functionalized samples showed very activities greater than 85 µmol CO/g CNT/s with nearly 100% conversion. Analyses show that CO hydro-deoxygenation occurred at the C-O/O-H functional groups. It was found that while the products were similar to FT products, differences in selectivities were observed which, in turn, was a result of a different catalytic mechanism. These findings now open a new paradigm for CNT-based hydrogenation catalysts and constitute a defining point for obtaining clean, earth abundant, alternative fuels through the use of efficient and renewable catalyst.
Keywords: CNT, CO hydro-deoxygenation, DFT, liquid fuels, XPS, XTL.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 7781026 Viability of Slab Sliding System for Single Story Structure
Authors: C. Iihoshi, G.A. MacRae, G.W. Rodgers, J.G. Chase
Abstract:
Slab sliding system (SSS) with Coulomb friction interface between slab and supporting frame is a passive structural vibration control technology. The system can significantly reduce the slab acceleration and accompanied lateral force of the frame. At the same time it is expected to cause the slab displacement magnification by sliding movement. To obtain the general comprehensive seismic response of a single story structure, inelastic response spectra were computed for a large ensemble of ground motions and a practical range of structural periods and friction coefficient values. It was shown that long period structures have no trade-off relation between force reduction and displacement magnification with respect to elastic response, unlike short period structures. For structures with the majority of mass in the slab, the displacement magnification value can be predicted according to simple inelastic displacement relation for inelastically responding SDOF structures because the system behaves elastically to a SDOF structure.
Keywords: Earthquake, Isolation, Slab, Sliding.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19281025 Experimental and Numerical Analysis of Built-In Thermoelectric Generator Modules with an Elliptical Pin-Fin Heat Sink
Authors: J. Y. Jang, C. Y. Tseng
Abstract:
A three-dimensional numerical model of thermoelectric generator (TEG) modules attached to a large chimney plate is proposed and solved numerically using a control volume based finite difference formulation. The TEG module consists of a thermoelectric generator, an elliptical pin-fin heat sink, and a cold plate for water cooling. In the chimney, the temperature of flue gases is 450-650K. Although the TEG hot-side temperature and thus the electric power output can be increased by inserting an elliptical pin-fin heat sink into the chimney tunnel to increase the heat transfer area, the pin fin heat sink would cause extra pumping power at the same time. The main purpose of this study is to analyze the effects of geometrical parameters on the electric power output and chimney pressure drop characteristics. The effects of different operating conditions, including various inlet velocities (Vin= 1, 3, 5 m/s), inlet temperatures (Tgas = 450, 550, 650K) and different fin height (0 to 150 mm) are discussed in detail. The predicted numerical data for the power vs. current (P-I) curve are in good agreement (within 11%) with the experimental data.
Keywords: Thermoelectric generator, Waste heat recovery, Elliptical pin-fin heat sink.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 24521024 The Impact of Local Decision-Making in Regional Development Schemes on the Achievement of Efficiency in EU Funds
Authors: Kuyucu Helvacioglu Asli Deniz, Tektas Arzu
Abstract:
European Union candidate status provides a strong motivation for decision-making in the candidate countries in shaping the regional development policy where there is an envisioned transfer of power from center to the periphery. The process of Europeanization anticipates the candidate countries configure their regional institutional templates in the context of the requirements of the European Union policies and introduces new instruments of incentive framework of enlargement to be employed in regional development schemes. It is observed that the contribution of the local actors to the decision making in the design of the allocation architectures enhances the efficiency of the funds and increases the positive effects of the projects funded under the regional development objectives. This study aims at exploring the performances of the three regional development grant schemes in Turkey, established and allocated under the pre-accession process with a special emphasis given to the roles of the national and local actors in decision-making for regional development. Efficiency analyses have been conducted using the DEA methodology which has proved to be a superior method in comparative efficiency and benchmarking measurements. The findings of this study as parallel to similar international studies, provides that the participation of the local actors to the decision-making in funding contributes both to the quality and the efficiency of the projects funded under the EU schemes.Keywords: Efficiency, European Union Funds, RegionalDevelopment, Turkey
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16471023 Effects of Polluted Water on the Metallic Water Pipelines
Authors: Abdul-Khaliq M. Hussain, Bashir A. Tantosh, El-Sadeg A. Abdalla
Abstract:
Corrosion of metallic water pipelines buried below ground surface is a function of the nature of the surrounding soil and groundwater. This gives the importance of knowing the physical and chemical characteristics of the pipe-s surrounding environment. The corrosion of externally – unprotected metallic water pipelines, specially ductile iron pipes, in localities with aggressive soil conditions is becoming a significant problem. Anticorrosive protection for metallic water pipelines, their fittings and accessories is very important, because they may be attached by corrosion with time. The tendency of a metallic substrate to corrode is a function of the surface characteristics of the metal and of the metal/protective film interface, the physical, electrical and electrochemical properties of the film, and the nature of the environment in which the pipelines system is placed. In this work the authors have looked at corrosion problems of water pipelines and their control. The corrosive properties of groundwater and soil environments are reviewed, and parameters affecting corrosion are discussed. The purpose of this work is to provide guidelines for materials selection in water and soil environments, and how the water pipelines can be protected against metallic corrosion.Keywords: Corrosion, Drinking Water, Metallic WaterPipelines, Polluted Water.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1807