Search results for: Mixed Reality
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 947

Search results for: Mixed Reality

377 Use of Benin Laterites for the Mix Design of Structural Concrete

Authors: Yémalin D. Agossou, André Lecomte, Rémi Boissiere, Edmond C. Adjovi, Abdelouahab Khelil

Abstract:

This paper presents a mixed design trial of structural concretes with laterites from Benin. These materials are often the only granular resources readily available in many tropical regions. In the first step concretes were designed with raw laterites, but the performances obtained were rather disappointing in spite of high cement dosages. A detailed physical characterization of these materials then showed that they contained a significant proportion of fine clays, and that the coarsest fraction (gravel) contained a variety of facies, some of which were not very dense or indurated. Washing these laterites, and even the elimination of the most friable grains of the gravel fraction, made it possible to obtain concretes with satisfactory properties in terms of workability, density and mechanical strength. However, they were found to be slightly less stiff than concretes made with more traditional aggregates. It is therefore possible to obtain structural concretes with only laterites and cement but at the cost of eliminating some of their granular constituents.

Keywords: Laterites, aggregates, concretes, mix design, mechanical properties.

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376 Phenotypic and Genetic Parameters of Pre-Weaning Growth Traits in Gentile di Puglia Lambs

Authors: M. Selvaggi, F. Pinto, A. R. Pesce Delfino, A. Vicenti, C. Dario

Abstract:

Data from 1731 Gentile di Puglia lambs, sired by 65 rams over a 5-year period were analyzed by a mixed model to estimate the variance components for heritability. The considered growth traits were: birth weight (BW), weight at 30 days of age (W30) and average daily gain from birth to 30 days of age (DG). Year of birth, sex of lamb, type of birth (single or twin), dam age at lambing and farm were significant sources of variation for all the considered growth traits. The average lamb weights were 3.85±0.16 kg at birth, 9.57±0.91 kg at 30 days of age and the average daily gain was 191±14 g. Estimates of heritability were 0.33±0.05, 0.41±0.06 and 0.16±0.05 respectively for the same traits. These values suggest there is a good opportunity to improve Gentile di Puglia lambs by selecting animals for growth traits.

Keywords: heritability estimate, growth traits, lambs, Gentile diPuglia.

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375 Utilizing Dredged Sediment for Enhancing Growth of Eelgrass in Artificially Prepared Substrates

Authors: Amelia B. Hizon-Fradejas, Yoichi Nakano, Satoshi Nakai, Wataru Nishijima, Mitsumasa Okada

Abstract:

Dredged sediment (DS) was utilized as source of silt-clay and organic matter in artificially prepared eelgrass substrates with mountain sand (MS) as the sand media. Addition of DS showed improved growth of eelgrass in the mixed substrates. Increase in added DS up to 15% silt-clay showed increased shoot growth but additional DS in 20% silt-clay mixture didn-t result to further increase in eelgrass growth. Improved root establishment were also found for plants in pots with added DS as shown by the increased resistance to uprooting, increased number of rhizome nodes and longer roots. Results demonstrated that addition of DS may be beneficial to eelgrass up to a certain extent only and too much of it might be harmful to eelgrass plants.

Keywords: Dredged sediment, eelgrass, eelgrass bed restoration, mountain sand, Zostera marina.

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374 Environmental Modeling of Storm Water Channels

Authors: L. Grinis

Abstract:

Turbulent flow in complex geometries receives considerable attention due to its importance in many engineering applications. It has been the subject of interest for many researchers. Some of these interests include the design of storm water channels. The design of these channels requires testing through physical models. The main practical limitation of physical models is the so called “scale effect”, that is, the fact that in many cases only primary physical mechanisms can be correctly represented, while secondary mechanisms are often distorted. These observations form the basis of our study, which centered on problems associated with the design of storm water channels near the Dead Sea, in Israel. To help reach a final design decision we used different physical models. Our research showed good coincidence with the results of laboratory tests and theoretical calculations, and allowed us to study different effects of fluid flow in an open channel. We determined that problems of this nature cannot be solved only by means of theoretical calculation and computer simulation. This study demonstrates the use of physical models to help resolve very complicated problems of fluid flow through baffles and similar structures. The study applies these models and observations to different construction and multiphase water flows, among them, those that include sand and stone particles, a significant attempt to bring to the testing laboratory a closer association with reality.

Keywords: Baffles, open channel, physical modeling.

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373 The Code-Mixing of Japanese, English and Thai in Line Chat

Authors: Premvadee Na Nakornpanom

Abstract:

Code- mixing in spontaneous speech has been widely discussed, but not in virtual situations; especially in context of the third language learning students. Thus, this study is an attempt to explore the linguistic characteristics of the mixing of Japanese, English and Thai in a mobile Line chat room by students with their background of English as L2, Japanese as L3 and Thai as mother tongue. The result found that insertion of Thai content words is a very common linguistic phenomenon embedded with the other two languages in the sentences. As chatting is to be ‘relational’ or ‘interactional’, it affected the style of lexical choices to be speech-like, more personal and emotionally-related. A personal pronoun in Japanese is often mixed into the sentences. The Japanese sentence-final question particle か “ka” was added to the end of the sentence based on Thai grammar rules. Some unique characteristics were created while chatting.

Keywords: Code-mixing, Japanese, English, Thai, Line chat.

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372 Authenticity Issues of Social Media: Credibility, Quality and Reality

Authors: Shahrinaz Ismail, Roslina Abdul Latif

Abstract:

Social media has led to paradigm shifts in ways people work and do business, interact and socialize, learn and obtain knowledge. So much so that social media has established itself as an important spatial extension of this nation-s historicity and challenges. Regardless of the enabling reputation and recommendation features through social networks embedded in the social media system, the overflow of broadcasted and publicized media contents turns the table around from engendering trust to doubting the trust system. When the trust is at doubt, the effects include deactivation of accounts and creation of multiple profiles, which lead to the overflow of 'ghost' contents (i.e. “the abundance of abandoned ships"). In most literature, the study of trust can be related to culture; hence the difference between Western-s “openness" and Eastern-s “blue-chip" concepts in networking and relationships. From a survey on issues and challenges among Malaysian social media users, 'authenticity' emerges as one of the main factors that causes and is caused by other factors. The other issue that has surfaced is credibility either in terms of message/content and source. Another is the quality of the knowledge that is shared. This paper explores the terrains of this critical space which in recent years has been dominated increasingly by, arguably, social networks embedded in the social media system, the overflow of broadcasted and publicized media content.

Keywords: Authenticity, credibility, knowledge quality and social media.

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371 Properties of Bio-Phenol Formaldehyde Composites Filled with Empty Fruit Bunch Fiber

Authors: Sharifah Nabihah Syed Jaafar, Umar Adli Amran, Rasidi Roslan, Chia Chin Hua, Sarani Zakaria

Abstract:

Bio-composites derived from plant fiber and/or bioderived polymer, are likely more ecofriendly and demonstrate competitive performance with petroleum based composites. In this research, the bio phenol-formaldehyde (bio-PF) was used as a matrix and oil palm empty fruit bunch fiber (EFB) as reinforcement. The matrix was synthesized via liquefaction and condensation to enhance the combination of phenol and formaldehyde, during the process. Then, the bio-PF was mixed with different percentage of EFB (5%, 10%, 15% and 20%) and molded at 180oC. The samples that viewed under scanning electron microscopy (SEM) showed an excellent wettability and interaction between EFB and matrix. Samples of 10% EFB gave the optimum properties of impact and hardness meanwhile sample 15% of EFB gave the highest reading of flexural modulus (MOE) and flexural strength (MOR). For thermal stability analysis, it was found that the weight loss and the activation energy (Ea) of the bio-composites samples were decreased as the filler content increased.

Keywords: EFB, liquefaction, phenol formaldehyde, lignin.

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370 Poor Medical Waste Management (MWM) Practices and Its Risks to Human Health and the Environment: A Literature Review

Authors: Babanyara Y. Y., Ibrahim D. B., Garba T., Bogoro A. G., Abubakar, M. Y.

Abstract:

Medical care is vital for our life, health and well-being. But the waste generated from medical activities can be hazardous, toxic and even lethal because of their high potential for diseases transmission. The hazardous and toxic parts of waste from healthcare establishments comprising infectious, medical and radioactive material as well as sharps constitute a grave risks to mankind and the environment, if these are not properly treated / disposed or are allowed to be mixed with other municipal waste. In Nigeria, practical information on this aspect is inadequate and research on the public health implications of poor management of medical wastes is few and limited in scope. Findings drawn from Literature particularly in the third world countries highlights financial problems, lack of awareness of risks involved in MWM, lack of appropriate legislation and lack of specialized MWM staff. The paper recommends how MWM practices can be improved in medical facilities.

Keywords: Environmental pollution, infectious, management, medical waste, public health.

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369 Effects of Mach Number and Angle of Attack on Mass Flow Rates and Entropy Gain in a Supersonic Inlet

Authors: Taher Fodeibou, Ziaul Huque, Jenny Galvis

Abstract:

A parametric study of a mixed-compression supersonic inlet is performed and reported. The effects of inlet Mach Numbers, varying from 4 to 10, and angle of attack, varying from 0 to 10, are reported for a constant inlet dynamic pressure. The paper looked at the variations of mass flow rates through the inlet, gain in entropy through the inlet, and the angles of the external oblique shocks. The mass flow rates were found to decrease monotonically with Mach numbers and increase with angle of attacks. On the other hand the entropy gain through the inlet increased with increasing Mach number and angle of attack. The variation in static pressure was found to be identical from the inlet throat to the exit for Mach number values higher than 6.

Keywords: Angle of attack, entropy gain, mass flow rates, supersonic inlets.

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368 Integrated ACOR/IACOMV-R-SVM Algorithm

Authors: Hiba Basim Alwan, Ku Ruhana Ku-Mahamud

Abstract:

A direction for ACO is to optimize continuous and mixed (discrete and continuous) variables in solving problems with various types of data. Support Vector Machine (SVM), which originates from the statistical approach, is a present day classification technique. The main problems of SVM are selecting feature subset and tuning the parameters. Discretizing the continuous value of the parameters is the most common approach in tuning SVM parameters. This process will result in loss of information which affects the classification accuracy. This paper presents two algorithms that can simultaneously tune SVM parameters and select the feature subset. The first algorithm, ACOR-SVM, will tune SVM parameters, while the second IACOMV-R-SVM algorithm will simultaneously tune SVM parameters and select the feature subset. Three benchmark UCI datasets were used in the experiments to validate the performance of the proposed algorithms. The results show that the proposed algorithms have good performances as compared to other approaches.

Keywords: Continuous ant colony optimization, incremental continuous ant colony, simultaneous optimization, support vector machine.

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367 Liveability of Kuala Lumpur City Centre: An Evaluation of the Happiness Level of the Streets- Activities

Authors: Shuhana Shamsuddin, Nur Rasyiqah Abu Hassan, Ahmad Bashri Sulaiman

Abstract:

Liveable city is referred to as the quality of life in an area that contributes towards a safe, healthy and enjoyable place. This paper discusses the role of the streets- activities in making Kuala Lumpur a liveable city and the happiness level of the residents towards the city-s street activities. The study was conducted using the residents of Kuala Lumpur. A mixed method technique is used with the quantitative data as a main data and supported by the qualitative data. Data were collected using questionnaires, observation and also an interview session with a sample of residents of Kuala Lumpur. The sampling technique is based on multistage cluster data sampling. The findings revealed that, there is still no significant relationship between the length of stay of the resident in Kuala Lumpur with the happiness level towards the street activities that occurred in the city.

Keywords: Liveable city, activities, urban design quality, quality of life, happiness level.

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366 A Multi-Objective Optimization Model to the Integrating Flexible Process Planning And Scheduling Based on Modified Particle Swarm Optimization Algorithm (MPSO)

Authors: R. Sahraian, A. Karampour Haghighi, E. Ghasemi

Abstract:

Process planning and production scheduling play important roles in manufacturing systems. In this paper a multiobjective mixed integer linear programming model is presented for the integrated planning and scheduling of multi-product. The aim is to find a set of high-quality trade-off solutions. This is a combinatorial optimization problem with substantially large solution space, suggesting that it is highly difficult to find the best solutions with the exact search method. To account for it, a PSO-based algorithm is proposed by fully utilizing the capability of the exploration search and fast convergence. To fit the continuous PSO in the discrete modeled problem, a solution representation is used in the algorithm. The numerical experiments have been performed to demonstrate the effectiveness of the proposed algorithm.

Keywords: Integrated process planning and scheduling, multi objective, MILP, Particle swarm optimization

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365 Heavy Metal Reduction in Plant Using Soil Amendment

Authors: C. Chaiyaraksa, T. Khamko

Abstract:

This study investigated the influence of limestone and sepiolite on heavy metals accumulation in the soil and soybean. The soil was synthesized to contaminate with zinc 150 mg/kg, copper 100 mg/kg, and cadmium 1 mg/kg. The contaminated soil was mixed with limestone and sepiolite at the ratio of 1:0, 0:1, 1:1, and 2:1. The amount of soil modifier added to soil was 0.2%, 0.4%, and 0.8%. The metals determination was performed on soil both before and after soybean planting and in the root, shoot, and seed of soybean after harvesting. The study was also on metal translocate from root to seed and on bioaccumulation factor. Using of limestone and sepiolite resulted in a reduction of metals accumulated in soybean. For soil containing a high concentration of copper, cadmium, and zinc, a mixture of limestone and sepiolite (1:1) was recommended to mix with soil with the amount of 0.2%. Zinc could translocate from root to seed more than copper, and cadmium. From studying the movement of metals from soil to accumulate in soybean, the result was that soybean could absorb the highest amount of cadmium, followed by zinc, and copper, respectively.

Keywords: Heavy metals, limestone, sepiolite, soil, soybean.

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364 Image Analysis of Fine Structures of Supercavitation in the Symmetric Wake of a Cylinder

Authors: Y. Obikane , M.Kaneko, K.Kakioka, K.Ogura

Abstract:

The fine structure of supercavitation in the wake of a symmetrical cylinder is studied with high-speed video cameras. The flow is observed in a cavitation tunnel at the speed of 8m/sec when the sidewall and the wake are partially filled with the massive cavitation bubbles. The present experiment observed that a two-dimensional ripple wave with a wave length of 0.3mm is propagated in a downstream direction, and then abruptly increases to a thicker three-dimensional layer. IR-photography recorded that the wakes originated from the horseshoe vortexes alongside the cylinder. The wake was developed to inside the dead water zone, which absorbed the bubbly wake propelled from the separated vortices at the center of the cylinder. A remote sensing classification technique (maximum most likelihood) determined that the surface porosity was 0.2, and the mean speed in the mixed wake was 7m/sec. To confirm the existence of two-dimensional wave motions in the interface, the experiments were conducted at a very low frequency, and showed similar gravity waves in both the upper and lower interfaces.

Keywords: Supercavitation, density gradient correlation

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363 Autonomic Sonar Sensor Fault Manager for Mobile Robots

Authors: Martin Doran, Roy Sterritt, George Wilkie

Abstract:

NASA, ESA, and NSSC space agencies have plans to put planetary rovers on Mars in 2020. For these future planetary rovers to succeed, they will heavily depend on sensors to detect obstacles. This will also become of vital importance in the future, if rovers become less dependent on commands received from earth-based control and more dependent on self-configuration and self-decision making. These planetary rovers will face harsh environments and the possibility of hardware failure is high, as seen in missions from the past. In this paper, we focus on using Autonomic principles where self-healing, self-optimization, and self-adaption are explored using the MAPE-K model and expanding this model to encapsulate the attributes such as Awareness, Analysis, and Adjustment (AAA-3). In the experimentation, a Pioneer P3-DX research robot is used to simulate a planetary rover. The sonar sensors on the P3-DX robot are used to simulate the sensors on a planetary rover (even though in reality, sonar sensors cannot operate in a vacuum). Experiments using the P3-DX robot focus on how our software system can be adapted with the loss of sonar sensor functionality. The autonomic manager system is responsible for the decision making on how to make use of remaining ‘enabled’ sonars sensors to compensate for those sonar sensors that are ‘disabled’. The key to this research is that the robot can still detect objects even with reduced sonar sensor capability.

Keywords: Autonomic, self-adaption, self-healing, self-optimization.

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362 Happiness, Media and Sustainability of Communities in Donkeaw, Mearim District, Chiang Mai, Thailand

Authors: Panida Jongsuksomsakul

Abstract:

This study of the ‘happiness’ and ‘sustainability’ in the community of Donkeaw, Amphoe Mae Rim, Chiang Mai Province during the non-election period in Thailand, noted that their happiness levels are in the middle-average range. This was found using a mixed approach of qualitative and quantitative methods (N = 386, α = 0.05). The study explores indicators for six aspects of well-being and happiness, including, good local governance, administrative support for the health system that maintains people’s mental and physical health, environment and weather, job security and a regular income aids them in managing a sustainable lifestyle. The impact of economic security and community relationships on social and cultural capital, and the way these aspects impact on the life style of the community, affects the sustainable well-being of people. Moreover, living with transparency and participatory communication led to diverse rewards in many areas.

Keywords: Communication, happiness, well-being, Donkeaw community, social and cultural capital.

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361 A Study of the Growth of Single-Phase Mg0.5Zn0.5O Films for UV LED

Authors: Hong Seung Kim, Chang Hoi Kim, Lili Yue

Abstract:

Single-phase, high band gap energy Zn0.5Mg0.5O films were grown under oxygen pressure, using pulse laser deposition with a Zn0.5Mg0.5O target. Structural characterization studies revealed that the crystal structures of the ZnX-1MgXO films could be controlled via changes in the oxygen pressure. TEM analysis showed that the thickness of the deposited Zn1-xMgxO thin films was 50–75 nm. As the oxygen pressure increased, we found that one axis of the crystals did not show a very significant increase in the crystallization compared with that observed at low oxygen pressure. The X-ray diffraction peak intensity for the hexagonal-ZnMgO (002) plane increased relative to that for the cubic-ZnMgO (111) plane. The corresponding c-axis of the h-ZnMgO lattice constant increased from 5.141 to 5.148 Å, and the a-axis of the c-ZnMgO lattice constant decreased from 4.255 to 4.250 Å. EDX analysis showed that the Mg content in the mixed-phase ZnMgO films decreased significantly, from 54.25 to 46.96 at.%. As the oxygen pressure was increased from 100 to 150 mTorr, the absorption edge red-shifted from 3.96 to 3.81 eV; however, a film grown at the highest oxygen pressure tested here (200 mTorr).

Keywords: MgO, UV LED, ZnMgO, ZnO.

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360 Investigation of the Main Trends of Tourist Expenses in Georgia

Authors: Nino Abesadze, Marine Mindorashvili, Nino Paresashvili

Abstract:

The main purpose of the article is to make complex statistical analysis of tourist expenses of foreign visitors. We used mixed technique of selection that implies rules of random and proportional selection. Computer software SPSS was used to compute statistical data for corresponding analysis. Corresponding methodology of tourism statistics was implemented according to international standards. Important information was collected and grouped from the major Georgian airports. Techniques of statistical observation were prepared. A representative population of foreign visitors and a rule of selection of respondents were determined. We have a trend of growth of tourist numbers and share of tourists from post-soviet countries constantly increases. Level of satisfaction with tourist facilities and quality of service has grown, but still we have a problem of disparity between quality of service and prices. The design of tourist expenses of foreign visitors is diverse; competitiveness of tourist products of Georgian tourist companies is higher.

Keywords: Tourist, expenses, methods, statistics, analysis.

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359 Design of Digital IIR filters with the Advantages of Model Order Reduction Technique

Authors: K.Ramesh, A.Nirmalkumar, G.Gurusamy

Abstract:

In this paper, a new model order reduction phenomenon is introduced at the design stage of linear phase digital IIR filter. The complexity of a system can be reduced by adopting the model order reduction method in their design. In this paper a mixed method of model order reduction is proposed for linear IIR filter. The proposed method employs the advantages of factor division technique to derive the reduced order denominator polynomial and the reduced order numerator is obtained based on the resultant denominator polynomial. The order reduction technique is used to reduce the delay units at the design stage of IIR filter. The validity of the proposed method is illustrated with design example in frequency domain and stability is also examined with help of nyquist plot.

Keywords: Error index (J), Factor division method, IIR filter, Nyquist plot, Order reduction.

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358 Experimental Chevreul’s Salt Production Methods on Copper Recovery

Authors: Turan Çalban, Oral Laçin, Abdüsselam Kurtbas

Abstract:

Experimental production methods of Chevreul’s salt being an intermediate stage product in copper recovery were investigated on this article. Chevreul’s salt, Cu2SO3.CuSO3.2H2O, being a mixed valence copper sulphite compound, has been obtained by using different methods and reagents. Chevreul’s salt has an intense brick-red color. It is highly stable and expensive. The production of Chevreul’s salt plays a key role in hydrometallurgy. Thermodynamic tendency on precipitation of Chevreul’s salt is related to pH and temperature. Besides, SO2 gaseous is a versatile reagent for precipitating of copper sulphites, Using of SO2 for selective precipitation can be made by appropriate adjustments of pH and temperature. Chevreul’s salt does not form in acidic solutions if those solutions contains considerable amount of sulfurous acid. It is necessary to maintain between pH 2–4.5, because, solubility of Chevreul’s salt increases with decreasing of pH values. Also, the region which Chevreul’s salt is stable can be seen from the potentialpH diagram.

Keywords: Chevreul’s salt, copper recovery, copper sulphite, stage product.

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357 Impact of Four Reading and Library Factors on the Grade Average of Ugandan Secondary School Students: A Quantitative Study

Authors: Valeda Dent

Abstract:

This study explores reading and library factors related to secondary school student academic outcomes in rural areas in Uganda. This mixed methods study utilized quantitative data collected as part of a more extensive project to explore six student factors in relation to students’ school, library, and home environments. The Kitengesa Community Library in Uganda (www.kitengesalibrary.org) served as the site for this study. The factors explored for this study include reading frequency, library use frequency, library access, overall grade average (OGA), and presence and type of reading materials in the home. Results indicated that both reading frequency and certain types of reading materials read for recreational purposes are correlated with higher OGA. Reading frequency was positively correlated with student OGA for all students.

Keywords: Rural village libraries, secondary school students, reading, academic achievement.

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356 Silver Nanoparticles-Enhanced Luminescence Spectra of Silicon Nanocrystals

Authors: Khamael M. Abualnaja, Lidija Šiller, Benjamin R. Horrocks

Abstract:

Metal-enhanced Luminescence of silicon nanocrystals (SiNCs) was determined using two different particle sizes of silver nanoparticles (AgNPs). SiNCs have been characterized by scanning electron microscopy (SEM), high resolution transmission electron microscopy (HRTEM), Fourier transform infrared spectroscopy (FTIR) and X-ray photoelectron spectroscopy (XPS). It is found that the SiNCs are crystalline with an average diameter of 65 nm and FCC lattice. AgNPs were synthesized using photochemical reduction of AgNO3 with sodium dodecyl sulphate (SDS). The enhanced luminescence of SiNCs by AgNPs was evaluated by confocal Raman microspectroscopy. Enhancement up to x9 and x3 times were observed for SiNCs that mixed with AgNPs which have an average particle size of 100 nm and 30 nm, respectively. Silver NPs-enhanced luminescence of SiNCs occurs as a result of the coupling between the excitation laser light and the plasmon bands of AgNPs; thus this intense field at AgNPs surface couples strongly to SiNCs.

Keywords: Luminescence, Silicon Nanocrystals, Silver Nanoparticles, Surface Enhanced Raman Spectroscopy (SERS).

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355 Effects of Temperature and Enzyme Concentration on Quality of Pineapple and Pawpaw Blended Juice

Authors: Ndidi F. Amulu, Calistus N. Ude, Patrick E. Amulu, Nneka N. Uchegbu

Abstract:

The effects of temperature and enzyme concentration on the quality of mixed pineapple and pawpaw blended fruits juice were studied. Extracts of the two fruit juices were separately treated at 70  for 15 min each so as to inactivate micro-organisms. They were analyzed and blended in different proportions of 70% pawpaw and 30% pineapple, 60% pawpaw and 40% pineapple, 50% pineapple and 50% pawpaw, 40% pawpaw and 60% pineapple. The characterization of the fresh pawpaw and pineapple juice before blending showed that the juices have good quality. The high water content of the product may have affected the viscosity, vitamin C content and total soluble solid of the blended juice to be low. The effects of the process parameters on the quality showed that better quality of the blended juice can be obtained within the optimum temperature range of (50-70 °C) and enzyme concentration range (0.12-0.18 w/v). The ratio of mix 60% pineapple juice: 40% pawpaw juice has better quality. This showed that pawpaw and pineapple juices can blend effectively to produce a quality juice.

Keywords: Clarification, pawpaw, pineapple, viscosity, vitamin C.

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354 Potential cIBR-Conjugated PLGA Nanoparticles for Selective Targeting to Leukemic Cells

Authors: Rungsinee Phongpradist, Sawitree Chiampanichayakul, Singkome Tima, Teruna J. Siahaan, Cory J. Berkland, Songyot Anuchapreeda, Chadarat Ampasavate

Abstract:

The expression of LFA-1 diverges from the physiological condition, thus active targeting carrier can provide the benefits from difference into LFA-1 expression in various conditions. Here, the selectivity of cIBR-conjugated nanoparticles (cIBR-NPs), in terms of uptake, was investigated using PBMCs, Mixed PBMCMolt- 3 cells and Molt-3 cells. The expressions of LFA-1 on Molt-3 cells, from flow cytometry and Western blot, possessed the highest level whereas PBMCs showed the lowest level. The kinetic uptake profiles of cIBR-NPs were obtained by flow cytometry, which the degree of cellular uptake presented a similar trend with the level of LFA-1 indicating the influence of LFA-1 expression on the cellular uptake of cIBR-NPs. The conformation of LFA-1 had a slight effect on the cellular uptake of cIBR-NPs. Overall we demonstrated that cIBR-NPs enhanced cellular uptake and improved the selectivity of drug carriers to LFA-1 on the leukemia cells, which related with the order of LFA-1 expression.

Keywords: cIBR, LFA-1, Molt-3, PBMCs

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353 Simulation of the Flow in a Packed-Bed with and without a Static Mixer by Using CFD Technique

Authors: Phavanee Narataruksa, Karn Pana-Suppamassadu, Sabaithip TungkamaniRungrote Kokoo, Prayut Jiamrittiwong

Abstract:

The major focus of this work was to characterize hydrodynamics in a packed-bed with and without static mixer by using Computational Fluid Dynamic (CFD). The commercial software: COMSOL MULTIPHYSICSTM Version 3.3 was used to simulate flow fields of mixed-gas reactants i.e. CO and H2. The packed-bed was a single tube with the inside diameter of 0.8 cm and the length of 1.2 cm. The static mixer was inserted inside the tube. The number of twisting elements was 1 with 0.8 cm in diameter and 1.2 cm in length. The packed-bed with and without static mixer were both packed with approximately 700 spherical structures representing catalyst pellets. Incompressible Navier-Stokes equations were used to model the gas flow inside the beds at steady state condition, in which the inlet Reynolds Number (Re) was 2.31. The results revealed that, with the insertion of static mixer, the gas was forced to flow radially inward and outward between the central portion of the tube and the tube wall. This could help improving the overall performance of the packed-bed, which could be utilized for heterogeneous catalytic reaction such as reforming and Fischer- Tropsch reactions.

Keywords: Packed Bed, Static Mixer, Computational Fluid Dynamic (CFD).

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352 Speed Characteristics of Mixed Traffic Flow on Urban Arterials

Authors: Ashish Dhamaniya, Satish Chandra

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Speed and traffic volume data are collected on different sections of four lane and six lane roads in three metropolitan cities in India. Speed data are analyzed to fit the statistical distribution to individual vehicle speed data and all vehicles speed data. It is noted that speed data of individual vehicle generally follows a normal distribution but speed data of all vehicle combined at a section of urban road may or may not follow the normal distribution depending upon the composition of traffic stream. A new term Speed Spread Ratio (SSR) is introduced in this paper which is the ratio of difference in 85th and 50th percentile speed to the difference in 50th and 15th percentile speed. If SSR is unity then speed data are truly normally distributed. It is noted that on six lane urban roads, speed data follow a normal distribution only when SSR is in the range of 0.86 – 1.11. The range of SSR is validated on four lane roads also.

Keywords: Normal distribution, percentile speed, speed spread ratio, traffic volume.

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351 The Effects of Biomass Parameters on the Dissolved Organic Carbon Removal in a Sponge Submerged Membrane Bioreactor

Authors: M. F. R. Zuthi, H. H. Ngo, W. S. Guo, T. T. Nguyen

Abstract:

A novel sponge submerged membrane bioreactor (SSMBR) was developed to effectively remove organics and nutrients from wastewater. Sponge is introduced within the SSMBR as a medium for the attached growth of biomass. This paper evaluates the effects of new and acclimatized sponges for dissolved organic carbon (DOC) removal from wastewater at different mixed liquor suspended solids- (MLSS) concentration of the sludge. It was observed in a series of experimental studies that the acclimatized sponge performed better than the new sponge whilst the optimum DOC removal could be achieved at 10g/L of MLSS with the acclimatized sponge. Moreover, the paper analyses the relationships between the MLSSsponge/MLSSsludge and the DOC removal efficiency of SSMBR. The results showed a non-linear relationship between the biomass parameters of the sponge and the sludge, and the DOC removal efficiency of SSMBR. A second-order polynomial function could reasonably represent these relationships.

Keywords: Acclimatization, Dissolved organic carbon, Mathematical model, Sponge submerged membrane bioreactor.

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350 Electrical Characteristics of Biomodified Electrodes using Nonfaradaic Electrochemical Impedance Spectroscopy

Authors: Yusmeeraz Yusof, Yoshiyuki Yanagimoto, Shigeyasu Uno, Kazuo Nakazato

Abstract:

We demonstrate a nonfaradaic electrochemical impedance spectroscopy measurement of biochemically modified gold plated electrodes using a two-electrode system. The absence of any redox indicator in the impedance measurements provide more precise and accurate characterization of the measured bioanalyte at molecular resolution. An equivalent electrical circuit of the electrodeelectrolyte interface was deduced from the observed impedance data of saline solution at low and high concentrations. The detection of biomolecular interactions was fundamentally correlated to electrical double-layer variation at modified interface. The investigations were done using 20mer deoxyribonucleic acid (DNA) strands without any label. Surface modification was performed by creating mixed monolayer of the thiol-modified single-stranded DNA and a spacer thiol (mercaptohexanol) by a two-step self-assembly method. The results clearly distinguish between the noncomplementary and complementary hybridization of DNA, at low frequency region below several hundreds Hertz.

Keywords: Biosensor, electrical double-layer, impedance spectroscopy, label free DNA.

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349 Assessment of Ultra-High Cycle Fatigue Behavior of EN-GJL-250 Cast Iron Using Ultrasonic Fatigue Testing Machine

Authors: Saeedeh Bakhtiari, Johannes Depessemier, Stijn Hertelé, Wim De Waele

Abstract:

High cycle fatigue comprising up to 107 load cycles has been the subject of many studies, and the behavior of many materials was recorded adequately in this regime. However, many applications involve larger numbers of load cycles during the lifetime of machine components. In this ultra-high cycle regime, other failure mechanisms play, and the concept of a fatigue endurance limit (assumed for materials such as steel) is often an oversimplification of reality. When machine component design demands a high geometrical complexity, cast iron grades become interesting candidate materials. Grey cast iron is known for its low cost, high compressive strength, and good damping properties. However, the ultra-high cycle fatigue behavior of cast iron is poorly documented. The current work focuses on the ultra-high cycle fatigue behavior of EN-GJL-250 (GG25) grey cast iron by developing an ultrasonic (20 kHz) fatigue testing system. Moreover, the testing machine is instrumented to measure the temperature and the displacement of  the specimen, and to control the temperature. The high resonance frequency allowed to assess the  behavior of the cast iron of interest within a matter of days for ultra-high numbers of cycles, and repeat the tests to quantify the natural scatter in fatigue resistance.

Keywords: GG25, cast iron, ultra-high cycle fatigue, ultrasonic test.

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348 Improving Lubrication Efficiency at High Sliding Speeds by Plasma Surface Texturing

Authors: Wei Zha, Jingzeng Zhang, Chen Zhao, Ran Cai, Xueyuan Nie

Abstract:

Cathodic plasma electrolysis (CPE) is used to create surface textures on cast iron samples for improving the tribological properties. Micro craters with confined size distribution were successfully formed by CPE process. These craters can generate extra hydrodynamic pressure that separates two sliding surfaces, increase the oil film thickness and accelerate the transition from boundary to mixed lubrication. It was found that the optimal crater size was 1.7 μm, at which the maximum lubrication efficiency was achieved. The Taguchi method was used to optimize the process parameters (voltage and roughness) for CPE surface texturing. The orthogonal array and the signal-to-noise ratio were employed to study the effect of each process parameter on the coefficient of friction. The results showed that with higher voltage and lower roughness, the lower friction coefficient can be obtained, and thus the lubrication can be more efficiently used for friction reduction.

Keywords: Cathodic plasma electrolysis, friction, lubrication, plasma surface texturing.

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