Search results for: Reconstruction of Variational Iteration Method (RVIM)
7891 Preconditioned Mixed-Type Splitting Iterative Method For Z-Matrices
Authors: Li Jiang, Baoguang Tian
Abstract:
In this paper, we present the preconditioned mixed-type splitting iterative method for solving the linear systems, Ax = b, where A is a Z-matrix. And we give some comparison theorems to show that the convergence rate of the preconditioned mixed-type splitting iterative method is faster than that of the mixed-type splitting iterative method. Finally, we give a numerical example to illustrate our results.Keywords: Z-matrix, mixed-type splitting iterative method, precondition, comparison theorem, linear system.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 12037890 Alternating Implicit Block FDTD Method For Scalar Wave Equation
Authors: N. M. Nusi, M. Othman, M. Suleiman, F. Ismail, N. Alias
Abstract:
In this paper, an alternating implicit block method for solving two dimensional scalar wave equation is presented. The new method consist of two stages for each time step implemented in alternating directions which are very simple in computation. To increase the speed of computation, a group of adjacent points is computed simultaneously. It is shown that the presented method increase the maximum time step size and more accurate than the conventional finite difference time domain (FDTD) method and other existing method of natural ordering.Keywords: FDTD, Scalar wave equation, alternating direction implicit (ADI), alternating group explicit (AGE), asymmetric approximation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19047889 A Calibration Device for Force-Torque Sensors
Authors: Nicolay Zarutskiy, Roman Bulkin
Abstract:
The paper deals with the existing methods of force-torque sensor calibration with a number of components from one to six, analyzed their advantages and disadvantages, the necessity of introduction of a calibration method. Calibration method and its constructive realization are also described here. A calibration method allows performing automated force-torque sensor calibration both with selected components of the main vector of forces and moments and with complex loading. Thus, two main advantages of the proposed calibration method are achieved: the automation of the calibration process and universality.Keywords: Automation, calibration, calibration device, calibration method, force-torque sensors.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 12907888 Coupled Galerkin-DQ Approach for the Transient Analysis of Dam-Reservoir Interaction
Authors: S. A. Eftekhari
Abstract:
In this paper, a numerical algorithm using a coupled Galerkin-Differential Quadrature (DQ) method is proposed for the solution of dam-reservoir interaction problem. The governing differential equation of motion of the dam structure is discretized by the Galerkin method and the DQM is used to discretize the fluid domain. The resulting systems of ordinary differential equations are then solved by the Newmark time integration scheme. The mixed scheme combines the simplicity of the Galerkin method and high accuracy and efficiency of the DQ method. Its accuracy and efficiency are demonstrated by comparing the calculated results with those of the existing literature. It is shown that highly accurate results can be obtained using a small number of Galerkin terms and DQM sampling points. The technique presented in this investigation is general and can be used to solve various fluid-structure interaction problems.
Keywords: Dam-reservoir system, Differential quadrature method, Fluid-structure interaction, Galerkin method, Integral quadrature method.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 18697887 Discontinuous Galerkin Method for Total Variation Minimization on Inpainting Problem
Authors: Xijian Wang
Abstract:
This paper is concerned with the numerical minimization of energy functionals in BV ( ) (the space of bounded variation functions) involving total variation for gray-scale 1-dimensional inpainting problem. Applications are shown by finite element method and discontinuous Galerkin method for total variation minimization. We include the numerical examples which show the different recovery image by these two methods.Keywords: finite element method, discontinuous Galerkin method, total variation minimization, inpainting
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 13437886 Numerical Solution of Second-Order Ordinary Differential Equations by Improved Runge-Kutta Nystrom Method
Authors: Faranak Rabiei, Fudziah Ismail, S. Norazak, Saeid Emadi
Abstract:
In this paper we developed the Improved Runge-Kutta Nystrom (IRKN) method for solving second order ordinary differential equations. The methods are two step in nature and require lower number of function evaluations per step compared with the existing Runge-Kutta Nystrom (RKN) methods. Therefore, the methods are computationally more efficient at achieving the higher order of local accuracy. Algebraic order conditions of the method are obtained and the third and fourth order method are derived with two and three stages respectively. The numerical results are given to illustrate the efficiency of the proposed method compared to the existing RKN methods.
Keywords: Improved Runge-Kutta Nystrom method, Two step method, Second-order ordinary differential equations, Order conditions
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 68507885 Reconstruction of the Most Energetic Modes in a Fully Developed Turbulent Channel Flow with Density Variation
Authors: Elteyeb Eljack, Takashi Ohta
Abstract:
Proper orthogonal decomposition (POD) is used to reconstruct spatio-temporal data of a fully developed turbulent channel flow with density variation at Reynolds number of 150, based on the friction velocity and the channel half-width, and Prandtl number of 0.71. To apply POD to the fully developed turbulent channel flow with density variation, the flow field (velocities, density, and temperature) is scaled by the corresponding root mean square values (rms) so that the flow field becomes dimensionless. A five-vector POD problem is solved numerically. The reconstructed second-order moments of velocity, temperature, and density from POD eigenfunctions compare favorably to the original Direct Numerical Simulation (DNS) data.
Keywords: Pattern Recognition, POD, Coherent Structures, Low dimensional modelling.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 13737884 On-line and Off-line POD Assisted Projective Integral for Non-linear Problems: A Case Study with Burgers-Equation
Authors: Montri Maleewong, Sirod Sirisup
Abstract:
The POD-assisted projective integration method based on the equation-free framework is presented in this paper. The method is essentially based on the slow manifold governing of given system. We have applied two variants which are the “on-line" and “off-line" methods for solving the one-dimensional viscous Bergers- equation. For the on-line method, we have computed the slow manifold by extracting the POD modes and used them on-the-fly along the projective integration process without assuming knowledge of the underlying slow manifold. In contrast, the underlying slow manifold must be computed prior to the projective integration process for the off-line method. The projective step is performed by the forward Euler method. Numerical experiments show that for the case of nonperiodic system, the on-line method is more efficient than the off-line method. Besides, the online approach is more realistic when apply the POD-assisted projective integration method to solve any systems. The critical value of the projective time step which directly limits the efficiency of both methods is also shown.
Keywords: Projective integration, POD method, equation-free.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 13557883 Introduction of the Fluid-Structure Coupling into the Force Analysis Technique
Authors: Océane Grosset, Charles Pézerat, Jean-Hugh Thomas, Frédéric Ablitzer
Abstract:
This paper presents a method to take into account the fluid-structure coupling into an inverse method, the Force Analysis Technique (FAT). The FAT method, also called RIFF method (Filtered Windowed Inverse Resolution), allows to identify the force distribution from local vibration field. In order to only identify the external force applied on a structure, it is necessary to quantify the fluid-structure coupling, especially in naval application, where the fluid is heavy. This method can be decomposed in two parts, the first one consists in identifying the fluid-structure coupling and the second one to introduced it in the FAT method to reconstruct the external force. Results of simulations on a plate coupled with a cavity filled with water are presented.Keywords: Fluid-structure coupling, inverse methods, naval, vibrations.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 11707882 Radiochemical Purity of 68Ga-BCA-Peptides: Separation of All 68Ga Species with a Single iTLC Strip
Authors: Anton A. Larenkov, Alesya Ya Maruk
Abstract:
In the present study, highly effective iTLC single strip method for the determination of radiochemical purity (RCP) of 68Ga-BCA-peptides was developed (with no double-developing, changing of eluents or other additional manipulation). In this method iTLC-SG strips and commonly used eluent TFAaq. (3-5 % (v/v)) are used. The method allows determining each of the key radiochemical forms of 68Ga (colloidal, bound, ionic) separately with the peaks separation being no less than 4 σ. Rf = 0.0-0.1 for 68Ga-colloid; Rf = 0.5-0.6 for 68Ga-BCA-peptides; Rf = 0.9-1.0 for ionic 68Ga. The method is simple and fast: For developing length of 75 mm only 4-6 min is required (versus 18-20 min for pharmacopoeial method). The method has been tested on various compounds (including 68Ga-DOTA-TOC, 68Ga-DOTA-TATE, 68Ga-NODAGA-RGD2 etc.). The cross-validation work for every specific form of 68Ga showed good correlation between method developed and control (pharmacopoeial) methods. The method can become convenient and much more informative replacement for pharmacopoeial methods, including HPLC.Keywords: DOTA-TATE, 68Ga, quality control, radiochemical purity, radiopharmaceuticals, iTLC.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20197881 Amphibious Architecture: A Benchmark for Mitigating Flood Risk
Authors: Lara L. Barbosa, Marco Imperadori
Abstract:
This article aims to define strategies for applying innovative technology so that housing in regions subject to floods can be more resilient to disasters. Based on case studies of seven amphibious and floating projects, it proposes design guidelines to implement this practice. Its originality consists of transposing a technology developed for fluctuating buildings for housing types in regions affected by flood disasters. The proposal could be replicated in other contexts, endowing vulnerable households with ability to resist rising water levels after a flood. The results of this study are design guidelines to adapt for houses in areas subject to flooding, contributing to the mitigation of this disaster.
Keywords: Amphibious housing, disaster resilience, floating architecture, flood mitigation, post-disaster reconstruction.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 667880 Stiffness Modeling of 3-PRS Mechanism
Authors: Xiaohui Han, Yuhan Wang, Jing Shi
Abstract:
This paper proposed a stiffness analysis method for a 3-PRS mechanism for welding thick aluminum plate using FSW technology. In the molding process, elastic deformation of lead-screws and links are taken into account. This method is based on the virtual work principle. Through a survey of the commonly used stiffness performance indices, the minimum and maximum eigenvalues of the stiffness matrix are used to evaluate the stiffness of the 3-PRS mechanism. Furthermore, A FEA model has been constructed to verify the method. Finally, we redefined the workspace using the stiffness analysis method.Keywords: 3-PRS, parallel mechanism, stiffness analysis, workspace.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 22667879 A New Method for Computing the Inverse Ideal in a Coordinate Ring
Authors: Abdolali Basiri
Abstract:
In this paper we present an efficient method for inverting an ideal in the ideal class group of a Cab curve by extending the method which is presented in [3]. More precisely we introduce a useful generator for the inverse ideal as a K[X]-module.
Keywords: Cab Curves, Ideal Class Group
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 10487878 Analytical solution of Gas Flow Through a Micro-Nano Porous Media by Homotopy Perturbation method
Authors: Jamal Amani Rad, Kourosh Parand
Abstract:
In this paper, we have applied the homotopy perturbation method (HPM) for obtaining the analytical solution of unsteady flow of gas through a porous medium and we have also compared the findings of this research with some other analytical results. Results showed a very good agreement between results of HPM and the numerical solutions of the problem rather than other analytical solutions which have previously been applied. The results of homotopy perturbation method are of high accuracy and the method is very effective and succinct.Keywords: Unsteady gas equation, Homotopy perturbation method(HPM), Porous medium, Nonlinear ODE
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 18887877 Electrical Field Around the Overhead Transmission Lines
Authors: S.S. Razavipour, M. Jahangiri, H. Sadeghipoor
Abstract:
In this paper, the computation of the electrical field distribution around AC high-voltage lines is demonstrated. The advantages and disadvantages of two different methods are described to evaluate the electrical field quantity. The first method is a seminumerical method using the laws of electrostatic techniques to simulate the two-dimensional electric field under the high-voltage overhead line. The second method which will be discussed is the finite element method (FEM) using specific boundary conditions to compute the two- dimensional electric field distributions in an efficient way.
Keywords: Electrical field, unloaded transmission lines, finite element method, electrostatic images technique.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 83697876 A Finite Point Method Based on Directional Derivatives for Diffusion Equation
Authors: Guixia Lv, Longjun Shen
Abstract:
This paper presents a finite point method based on directional derivatives for diffusion equation on 2D scattered points. To discretize the diffusion operator at a given point, a six-point stencil is derived by employing explicit numerical formulae of directional derivatives, namely, for the point under consideration, only five neighbor points are involved, the number of which is the smallest for discretizing diffusion operator with first-order accuracy. A method for selecting neighbor point set is proposed, which satisfies the solvability condition of numerical derivatives. Some numerical examples are performed to show the good performance of the proposed method.Keywords: Finite point method, directional derivatives, diffusionequation, method for selecting neighbor point set.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 13527875 A Method for Quality Inspection of Motors by Detecting Abnormal Sound
Authors: Tadatsugu Kitamoto
Abstract:
Recently, a quality of motors is inspected by human ears. In this paper, I propose two systems using a method of speech recognition for automation of the inspection. The first system is based on a method of linear processing which uses K-means and Nearest Neighbor method, and the second is based on a method of non-linear processing which uses neural networks. I used motor sounds in these systems, and I successfully recognize 86.67% of motor sounds in the linear processing system and 97.78% in the non-linear processing system.Keywords: Acoustical diagnosis, Neural networks, K-means, Short-time Fourier transformation
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 17007874 A New Approach for Mobile Agent Security
Authors: R. Haghighat far, H. Yarahmadi
Abstract:
A mobile agent is a software which performs an action autonomously and independently as a person or an organizations assistance. Mobile agents are used for searching information, retrieval information, filtering, intruder recognition in networks, and so on. One of the important issues of mobile agent is their security. It must consider different security issues in effective and secured usage of mobile agent. One of those issues is the integrity-s protection of mobile agents. In this paper, the advantages and disadvantages of each method, after reviewing the existing methods, is examined. Regarding to this matter that each method has its own advantage or disadvantage, it seems that by combining these methods, one can reach to a better method for protecting the integrity of mobile agents. Therefore, this method is provided in this paper and then is evaluated in terms of existing method. Finally, this method is simulated and its results are the sign of improving the possibility of integrity-s protection of mobile agents.Keywords: Integrity, Mobile Agent, Security.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 17597873 A Formatting Method for Transforming XML Data into HTML
Authors: Zhe JIN, Motomichi TOYAMA
Abstract:
In this paper, we propose a fixed formatting method of PPX(Pretty Printer for XML). PPX is a query language for XML database which has extensive formatting capability that produces HTML as the result of a query. The fixed formatting method is to completely specify the combination of variables and layout specification operators within the layout expression of the GENERATE clause of PPX. In the experiment, a quick comparison shows that PPX requires far less description compared to XSLT or XQuery programs doing the same tasks.
Keywords: PPX, XML, HTML, XSLT, XQuery, fixed formatting method.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 13647872 Impact of the Operation and Infrastructure Parameters to the Railway Track Capacity
Authors: Martin Kendra, Jaroslav Mašek, Juraj Čamaj, Matej Babin
Abstract:
The railway transport is considered as a one of the most environmentally friendly mode of transport. With future prediction of increasing of freight transport there are lines facing problems with demanded capacity. Increase of the track capacity could be achieved by infrastructure constructive adjustments. The contribution shows how the travel time can be minimized and the track capacity increased by changing some of the basic infrastructure and operation parameters, for example, the minimal curve radius of the track, the number of tracks, or the usable track length at stations. Calculation of the necessary parameter changes is based on the fundamental physical laws applied to the train movement, and calculation of the occupation time is dependent on the changes of controlling the traffic between the stations.Keywords: Curve radius, maximum curve speed, track mass capacity, reconstruction.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 18077871 Containment/Penetration Analysis for the Protection of Aircraft Engine External Configuration and Nuclear Power Plant Structures
Authors: Dong Wook Lee, Adrian Mistreanu
Abstract:
The authors have studied a method for analyzing containment and penetration using an explicit nonlinear Finite Element Analysis. This method may be used in the stage of concept design for the protection of external configurations or components of aircraft engines and nuclear power plant structures. This paper consists of the modeling method, the results obtained from the method and the comparison of the results with those calculated from simple analytical method. It shows that the containment capability obtained by proposed method matches well with analytically calculated containment capability.
Keywords: Computer Aided Engineering, CAE, containment analysis, Finite Element Analysis, FEA, impact analysis, penetration analysis.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 5397870 Simplex Method for Solving Linear Programming Problems with Fuzzy Numbers
Authors: S. H. Nasseri, E. Ardil, A. Yazdani, R. Zaefarian
Abstract:
The fuzzy set theory has been applied in many fields, such as operations research, control theory, and management sciences, etc. In particular, an application of this theory in decision making problems is linear programming problems with fuzzy numbers. In this study, we present a new method for solving fuzzy number linear programming problems, by use of linear ranking function. In fact, our method is similar to simplex method that was used for solving linear programming problems in crisp environment before.Keywords: Fuzzy number linear programming, rankingfunction, simplex method.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 35287869 Inverse Heat Transfer Analysis of a Melting Furnace Using Levenberg-Marquardt Method
Authors: Mohamed Hafid, Marcel Lacroix
Abstract:
This study presents a simple inverse heat transfer procedure for predicting the wall erosion and the time-varying thickness of the protective bank that covers the inside surface of the refractory brick wall of a melting furnace. The direct problem is solved by using the Finite-Volume model. The melting/solidification process is modeled using the enthalpy method. The inverse procedure rests on the Levenberg-Marquardt method combined with the Broyden method. The effect of the location of the temperature sensors and of the measurement noise on the inverse predictions is investigated. Recommendations are made concerning the location of the temperature sensor.Keywords: Melting furnace, inverse heat transfer, enthalpy method, Levenberg–Marquardt Method.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 13187868 Quartic Nonpolynomial Spline Solutions for Third Order Two-Point Boundary Value Problem
Authors: Talaat S. El-Danaf
Abstract:
In this paper, we develop quartic nonpolynomial spline method for the numerical solution of third order two point boundary value problems. It is shown that the new method gives approximations, which are better than those produced by other spline methods. Convergence analysis of the method is discussed through standard procedures. Two numerical examples are given to illustrate the applicability and efficiency of the novel method.Keywords: Quartic nonpolynomial spline, Two-point boundary value problem.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20097867 Students- Perception of the Evaluation System in Architecture Studios
Authors: Badiossadat Hassanpour, Nangkula Utaberta, Azami Zaharim, Nurakmal Goh Abdullah
Abstract:
Architecture education was based on apprenticeship models and its nature has not changed much during long period but the Source of changes was its evaluation process and system. It is undeniable that art and architecture education is completely based on transmitting knowledge from instructor to students. In contrast to other majors this transmitting is by iteration and practice and studio masters try to control the design process and improving skills in the form of supervision and criticizing. Also the evaluation will end by giving marks to students- achievements. Therefore the importance of the evaluation and assessment role is obvious and it is not irrelevant to say that if we want to know about the architecture education system, we must first study its assessment procedures. The evolution of these changes in western countries has literate and documented well. However it seems that this procedure has unregarded in Malaysia and there is a severe lack of research and documentation in this area. Malaysia as an under developing and multicultural country which is involved different races and cultures is a proper origin for scrutinizing and understanding the evaluation systems and acceptability amount of current implemented models to keep the evaluation and assessment procedure abreast with needs of different generations, cultures and even genders. This paper attempts to answer the questions of how evaluation and assessments are performed and how students perceive this evaluation system in the context Malaysia. The main advantage of this work is that it contributes in international debate on evaluation model.Keywords: Architecture, assessment, design studio, learning
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 28797866 Increased Signal to Noise Ratio in P300 Potentials by the Method of Coherent Self-Averaging in BCI Systems
Authors: Ricardo Espinosa
Abstract:
The coherent Self-Averaging (CSA), is a new method proposed in this work; applied to simulated signals evoked potentials related to events (ERP) to find the wave P300, useful systems in the brain computer interface (BCI). The CSA method cleans signal in the time domain of white noise through of successive averaging of a single signal. The method is compared with the traditional method, coherent averaging or synchronized (CA), showing optimal results in the improvement of the signal to noise ratio (SNR). The method of CSA is easy to implement, robust and applicable to any physiological time series contaminated with white noise
Keywords: Evoked potentials, wave P300, Coherent Self-averaging, brain - computer interface (BCI).
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 21447865 A New Inversion-free Method for Hermitian Positive Definite Solution of Matrix Equation
Authors: Minghui Wang, Juntao Zhang
Abstract:
An inversion-free iterative algorithm is presented for solving nonlinear matrix equation with a stepsize parameter t. The existence of the maximal solution is discussed in detail, and the method for finding it is proposed. Finally, two numerical examples are reported that show the efficiency of the method.
Keywords: Inversion-free method, Hermitian positive definite solution, Maximal solution, Convergence.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16067864 Wavelet and K-L Seperability Based Feature Extraction Method for Functional Data Classification
Authors: Jun Wan, Zehua Chen, Yingwu Chen, Zhidong Bai
Abstract:
This paper proposes a novel feature extraction method, based on Discrete Wavelet Transform (DWT) and K-L Seperability (KLS), for the classification of Functional Data (FD). This method combines the decorrelation and reduction property of DWT and the additive independence property of KLS, which is helpful to extraction classification features of FD. It is an advanced approach of the popular wavelet based shrinkage method for functional data reduction and classification. A theory analysis is given in the paper to prove the consistent convergence property, and a simulation study is also done to compare the proposed method with the former shrinkage ones. The experiment results show that this method has advantages in improving classification efficiency, precision and robustness.Keywords: classification, functional data, feature extraction, K-Lseperability, wavelet.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 14677863 Modified Levenberg-Marquardt Method for Neural Networks Training
Authors: Amir Abolfazl Suratgar, Mohammad Bagher Tavakoli, Abbas Hoseinabadi
Abstract:
In this paper a modification on Levenberg-Marquardt algorithm for MLP neural network learning is proposed. The proposed algorithm has good convergence. This method reduces the amount of oscillation in learning procedure. An example is given to show usefulness of this method. Finally a simulation verifies the results of proposed method.
Keywords: Levenberg-Marquardt, modification, neural network, variable learning rate.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 50487862 Derivative Spectrophotometry Applied to the Determination of Triprolidine Hydrochloride and Pseudoephedrine Hydrochloride in Tablets and Dissolution Testing
Authors: L. Sriphong, A. Chaidedgumjorn, K. Chaisuroj
Abstract:
A spectrophotometric method was developed for simultaneous quantification of pseudoephedrine hydrochloride (PSE) triprolidine hydrochloride (TRI) using second derivative method (zero-crossing technique). The second derivative amplitudes of PSE and TRI were measured at 271 and 321 nm, respectively. The calibration curves were linear in the range of 200 to 1,000 g/ml for PSE and 10 to 50 g/ml for TRI. The method was validated for specificity, accuracy, precision, limit of detection and limit of quantitation. The proposed method was applied to the assaying and dissolution of PSE and TRI in commercial tablets without any chemical separation. The results were compared with those obtained by the official USP31 method and statistical tests showed that there is no significant between the methods at 95% confidence level. The proposed method is simple, rapid and suitable for the routine quality control application. KeywordsTriprolidine, Pseudoephedrine, Derivative spectrophotometry, Dissolution testing.
Keywords: Triprolidine, Pseudoephedrine, Derivative spectrophotometry, Dissolution testing.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2251