Search results for: weak formulation.
614 Finite Element Approximation of the Heat Equation under Axisymmetry Assumption
Authors: Raphael Zanella
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This works deals with the finite element approximation of axisymmetric problems. The weak formulation of the heat equation under axisymmetry assumption is established for continuous finite elements. The weak formulation is implemented in a C++ solver with implicit time marching. The code is verified by space and time convergence tests using a manufactured solution. An example problem is solved with an axisymmetric formulation and with a 3D formulation. Both formulations lead to the same result but the code based on the axisymmetric formulation is mush faster due to the lower number of degrees of freedom. This confirms the correctness of our approach and the interest of using an axisymmetric formulation when it is possible.
Keywords: Axisymmetric problem, continuous finite elements, heat equation, weak formulation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 350613 Banach Lattices with Weak Dunford-Pettis Property
Authors: Khalid Bouras, Mohammed Moussa
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We introduce and study the class of weak almost Dunford-Pettis operators. As an application, we characterize Banach lattices with the weak Dunford-Pettis property. Also, we establish some sufficient conditions for which each weak almost Dunford-Pettis operator is weak Dunford-Pettis. Finally, we derive some interesting results.
Keywords: Almost Dunford-Pettis operator, weak Dunford-Pettis operator, eak almost Dunford-Pettis operator, almost Dunford-Pettis operator, weak Dunford-Pettis operator
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2038612 Weak Instability in Direct Integration Methods for Structural Dynamics
Authors: Shuenn-Yih Chang, Chiu-Li Huang
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Three structure-dependent integration methods have been developed for solving equations of motion, which are second-order ordinary differential equations, for structural dynamics and earthquake engineering applications. Although they generally have the same numerical properties, such as explicit formulation, unconditional stability and second-order accuracy, a different performance is found in solving the free vibration response to either linear elastic or nonlinear systems with high frequency modes. The root cause of this different performance in the free vibration responses is analytically explored herein. As a result, it is verified that a weak instability is responsible for the different performance of the integration methods. In general, a weak instability will result in an inaccurate solution or even numerical instability in the free vibration responses of high frequency modes. As a result, a weak instability must be prohibited for time integration methods.Keywords: Dynamic analysis, high frequency, integration method, overshoot, weak instability.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 670611 On Strong(Weak) Domination in Fuzzy Graphs
Authors: C.Natarajan, S.K.Ayyaswamy
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Let G be a fuzzy graph. Then D Ôèå V is said to be a strong (weak) fuzzy dominating set of G if every vertex v ∈ V -D is strongly (weakly) dominated by some vertex u in D. We denote a strong (weak) fuzzy dominating set by sfd-set (wfd-set). The minimum scalar cardinality of a sfd-set (wfd-set) is called the strong (weak) fuzzy domination number of G and it is denoted by γsf (G)γwf (G). In this paper we introduce the concept of strong (weak) domination in fuzzy graphs and obtain some interesting results for this new parameter in fuzzy graphs.
Keywords: Fuzzy graphs, fuzzy domination, strong (weak) fuzzy domination number.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3939610 Talent in Autism: Cognitive Style based on Weak Central Coherence and Special Sensory Characteristics in State of Kuwait: Case Study
Authors: Mariam Abdulaziz Y.Esmaeel
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The study aimed to identify the nature of autistic talent, the manifestations of their weak central coherence, and their sensory characteristics. The case study consisted of four talented autistic males. Two of them in drawing, one in clay formation and one in jigsaw puzzle. Tools of data collection were Group Embedded Figures Test, Block Design Test, Sensory Profile Checklist Revised, Interview forms and direct observation. Results indicated that talent among autistics emerges in limited domain and being extraordinary for each case. Also overlapping construction properties. Indeed, they show three perceptual aspects of weak central coherence: The weak in visual spatial-constructional coherence, the weak in perceptual coherence and the weak in verbal – semantic coherence. Moreover, the majority of the study cases used the three strategies of weak central coherence (segmentation, obliqueness and rotation). As for the sensory characteristics, all study cases have numbers of that characteristics that especially emerges in the visual system.Keywords: Autism, Central Coherence, Savant, Sensory characteristics, Talent.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2688609 Common Fixed Point Theorems for Co-Cyclic Weak Contractions in Compact Metric
Authors: Alemayehu Geremew Negash
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In this paper, we prove some common fixed point theorems for co-cyclic weak contractions in compact metric spaces.
Keywords: Cyclic weak contraction, Co-cyclic weak contraction, Co-cyclic representation, Common fixed point.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2212608 How are Equalities Defined, Strong or Weak on a Multiple Algebra?
Authors: Mona Taheri
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For the purpose of finding the quotient structure of multiple algebras such as groups, Abelian groups and rings, we will state concepts of ( strong or weak ) equalities on multiple algebras, which will lead us to research on how ( strong or weak) are equalities defined on a multiple algebra over the quotients obtained from it. In order to find a quotient structure of multiple algebras such as groups, Abelian groups and loops, a part of this article has been allocated to the concepts of equalities (strong and weak) of the defined multiple functions on multiple algebras. This leads us to do research on how defined equalities (strong and weak) are made in the multiple algebra on its resulted quotient.
Keywords: Multiple algebra, mathematics, universal algebra.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1247607 A New Integer Programming Formulation for the Chinese Postman Problem with Time Dependent Travel Times
Authors: Jinghao Sun, Guozhen Tan, Guangjian Hou
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The Chinese Postman Problem (CPP) is one of the classical problems in graph theory and is applicable in a wide range of fields. With the rapid development of hybrid systems and model based testing, Chinese Postman Problem with Time Dependent Travel Times (CPPTDT) becomes more realistic than the classical problems. In the literature, we have proposed the first integer programming formulation for the CPPTDT problem, namely, circuit formulation, based on which some polyhedral results are investigated and a cutting plane algorithm is also designed. However, there exists a main drawback: the circuit formulation is only available for solving the special instances with all circuits passing through the origin. Therefore, this paper proposes a new integer programming formulation for solving all the general instances of CPPTDT. Moreover, the size of the circuit formulation is too large, which is reduced dramatically here. Thus, it is possible to design more efficient algorithm for solving the CPPTDT in the future research.Keywords: Chinese Postman Problem, Time Dependent, Integer Programming, Upper Bound Analysis.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2739606 Isomorphism on Fuzzy Graphs
Authors: A.Nagoor Gani, J.Malarvizhi
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In this paper, the order, size and degree of the nodes of the isomorphic fuzzy graphs are discussed. Isomorphism between fuzzy graphs is proved to be an equivalence relation. Some properties of self complementary and self weak complementary fuzzy graphs are discussed.Keywords: complementary fuzzy graphs, co-weak isomorphism, equivalence relation, fuzzy relation, weak isomorphism.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 4075605 Application of He-s Amplitude Frequency Formulation for a Nonlinear Oscillator with Fractional Potential
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In this paper, He-s amplitude frequency formulation is used to obtain a periodic solution for a nonlinear oscillator with fractional potential. By calculation and computer simulations, compared with the exact solution shows that the result obtained is of high accuracy.
Keywords: He's amplitude frequency formulation, Periodic solution, Nonlinear oscillator, Fractional potential.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1366604 Weak Convergence of Mann Iteration for a Hybrid Pair of Mappings in a Banach Space
Authors: Alemayehu Geremew Negash
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We prove the weak convergence of Mann iteration for a hybrid pair of maps to a common fixed point of a selfmap f and a multivalued f nonexpansive mapping T in Banach space E.
Keywords: Common fixed point, Mann iteration, Multivalued mapping, weak convergence.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1637603 Effect of Magnetic Field on the Biological Clock through the Radical Pair Mechanism
Authors: Chathurika D. Abeyrathne, Malka N. Halgamuge, Peter M. Farrell
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There is an ongoing controversy in the literature related to the biological effects of weak, low frequency electromagnetic fields. The physical arguments and interpretation of the experimental evidence are inconsistent, where some physical arguments and experimental demonstrations tend to reject the likelihood of any effect of the fields at extremely low level. The problem arises of explaining, how the low-energy influences of weak magnetic fields can compete with the thermal and electrical noise of cells at normal temperature using the theoretical studies. The magnetoreception in animals involve radical pair mechanism. The same mechanism has been shown to be involved in the circadian rhythm synchronization in mammals. These reactions can be influenced by the weak magnetic fields. Hence, it is postulated the biological clock can be affected by weak magnetic fields and these disruptions to the rhythm can cause adverse biological effects. In this paper, likelihood of altering the biological clock via the radical pair mechanism is analyzed to simplify these studies of controversy.Keywords: Bio-effect, biological clock, magnetoreception, radical pair mechanism, weak magnetic field.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2323602 Characterization of Monoids by a Generalization of Flatness Property
Authors: Mahdiyeh Abbasi, Akbar Golchin
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It is well-known that, using principal weak flatness property, some important monoids are characterized, such as regular monoids, left almost regular monoids, and so on. In this article, we define a generalization of principal weak flatness called GP-Flatness, and will characterize monoids by this property of their right (Rees factor) acts. Also we investigate new classes of monoids called generally regular monoids and generally left almost regular monoids.Keywords: G-left stabilizing, GP-flatness, generally regular, principal weak flatness.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2166601 Development of Intelligent Time/Frequency Based Signal Detection Algorithm for Intrusion Detection System
Authors: Waqas Ahmed, S Sajjad Haider Zaidi
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For the past couple of decades Weak signal detection is of crucial importance in various engineering and scientific applications. It finds its application in areas like Wireless communication, Radars, Aerospace engineering, Control systems and many of those. Usually weak signal detection requires phase sensitive detector and demodulation module to detect and analyze the signal. This article gives you a preamble to intrusion detection system which can effectively detect a weak signal from a multiplexed signal. By carefully inspecting and analyzing the respective signal, this system can successfully indicate any peripheral intrusion. Intrusion detection system (IDS) is a comprehensive and easy approach towards detecting and analyzing any signal that is weakened and garbled due to low signal to noise ratio (SNR). This approach finds significant importance in applications like peripheral security systems.Keywords: Data Acquisition, fast frequency transforms, Lab VIEW software, weak signal detection.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2509600 MPSO based Model Order Formulation Scheme for Discrete PID Controller Design
Authors: S. N. Deepa, G. Sugumaran
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This paper proposes the novel model order formulation scheme to design a discrete PID controller for higher order linear time invariant discrete systems. Modified PSO (MPSO) based model order formulation technique has used to obtain the successful formulated second order system. PID controller is tuned to meet the desired performance specification by using pole-zero cancellation and proposed design procedures. Proposed PID controller is attached with both higher order system and formulated second order system. System specifications are tabulated and closed loop response is observed for stabilization process. The proposed method is illustrated through numerical examples from literature.Keywords: Discrete PID controller, Model Order Formulation, Modified Particle Swarm Optimization, Pole-Zero Cancellation
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1612599 Preparation and Characterization of M. × Piperita L. Oil Based Gel Formulation
Authors: Peeyush Kumar, Sapna Mishra, Anushree Malik, Santosh Satya
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The essential oil of M. × piperita L. was formulated into a topical gel. The prepared gel was characterized for its pH, viscosity, spreadiblity, consistency and extrudiblity, while its stability was evaluated under different temperature conditions. The prepared M. × piperita oil gel was clear and transparent. The pH value of developed gel was 6.6, while its viscosity was 1200 cP. Spreadability and consistency of the M. × piperita oil gel was 10.7 g.cm/sec and 7 mm, respectively. The prepared gel showed good extrudiblity. During the stability studies, no significant change in pH and viscosity as a function of time for gel was observed, indicating stability of prepared formulation. The gel developed in this study is expected to forward the usage of M. × piperita essential towards commercial application.Keywords: M. × piperita L., formulation, gel, characterization, stability
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3126598 Linguistic, Pragmatic and Evolutionary Factors in Wason Selection Task
Authors: Olimpia Matarazzo, Fabrizio Ferrara
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In two studies we tested the hypothesis that the appropriate linguistic formulation of a deontic rule – i.e. the formulation which clarifies the monadic nature of deontic operators - should produce more correct responses than the conditional formulation in Wason selection task. We tested this assumption by presenting a prescription rule and a prohibition rule in conditional vs. proper deontic formulation. We contrasted this hypothesis with two other hypotheses derived from social contract theory and relevance theory. According to the first theory, a deontic rule expressed in terms of cost-benefit should elicit a cheater detection module, sensible to mental states attributions and thus able to discriminate intentional rule violations from accidental rule violations. We tested this prevision by distinguishing the two types of violations. According to relevance theory, performance in selection task should improve by increasing cognitive effect and decreasing cognitive effort. We tested this prevision by focusing experimental instructions on the rule vs. the action covered by the rule. In study 1, in which 480 undergraduates participated, we tested these predictions through a 2 x 2 x 2 x 2 (type of the rule x rule formulation x type of violation x experimental instructions) between-subjects design. In study 2 – carried out by means of a 2 x 2 (rule formulation x type of violation) between-subjects design - we retested the hypothesis of rule formulation vs. the cheaterdetection hypothesis through a new version of selection task in which intentional vs. accidental rule violations were better discriminated. 240 undergraduates participated in this study. Results corroborate our hypothesis and challenge the contrasting assumptions. However, they show that the conditional formulation of deontic rules produces a lower performance than what is reported in literature.Keywords: Deontic reasoning; Evolutionary, linguistic, logical, pragmatic factors; Wason selection task
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1609597 Development and Evaluation of Gastro Retentive Floating Tablets of Ayurvedic Vati Formulation
Authors: Imran Khan Pathan, Anil Bhandari, Peeyush K. Sharma, Rakesh K. Patel, Suresh Purohit
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Floating tablets of Marichyadi Vati were developed with an aim to prolong its gastric residence time and increase the bioavailability of drug. Rapid gastrointestinal transit could result in incomplete drug release from the drug delivery system above the absorption zone leading to diminished efficacy of the administered dose. The tablets were prepared by wet granulation technique, using HPMC E50 LV act as Matrixing agent, Carbopol as floating enhancer, microcrystalline cellulose as binder, Sodium bi carbonate as effervescent agent with other excipients. The simplex lattice design was used for selection of variables for tablets formulation. Formulation was optimized on the basis of floating time and in vitro drug release. The results showed that the floating lag time for optimized formulation was found to be 61 second with about 97.32 % of total drug release within 3 hours. The vitro release profiles of drug from the formulation could be best expressed zero order with highest linearity r2 = 0.9943. It was concluded that the gastroretentive drug delivery system can be developed for Marichyadi Vati containing Piperine to increase the residence time of the drug in the stomach and thereby increasing bioavailability.
Keywords: Piperine, Marichyadi Vati, Gastroretentive drug delivery, Floating tablet.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2676596 Postbuckling Analysis of End Supported Rods under Self-Weight Using Intrinsic Coordinate Finite Elements
Authors: C. Juntarasaid, T. Pulngern, S. Chucheepsakul
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A formulation of postbuckling analysis of end supported rods under self-weight has been presented by the variational method. The variational formulation involving the strain energy due to bending and the potential energy of the self-weight, are expressed in terms of the intrinsic coordinates. The variational formulation is accomplished by introducing the Lagrange multiplier technique to impose the boundary conditions. The finite element method is used to derive a system of nonlinear equations resulting from the stationary of the total potential energy and then Newton-Raphson iterative procedure is applied to solve this system of equations. The numerical results demonstrate the postbluckled configurations of end supported rods under self-weight. This finite element method based on variational formulation expressed in term of intrinsic coordinate is highly recommended for postbuckling analysis of end-supported rods under self-weight.
Keywords: Variational method, postbuckling, finite element method, intrinsic coordinate.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 846595 Material Failure Process Simulation by Improve Finite Elements with Embedded Discontinuities
Authors: Juárez-Luna Gelacio, Ayala Gustavo, Retama-Velasco Jaime
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This paper shows the advantages of the material failure process simulation by improve finite elements with embedded discontinuities, using a new definition of traction vector, dependent on the discontinuity length and the angle. Particularly, two families of this kind of elements are compared: kinematically optimal symmetric and statically and kinematically optimal non-symmetric. The constitutive model to describe the behavior of the material in the symmetric formulation is a traction-displacement jump relationship equipped with softening after reaching the failure surface.
To show the validity of this symmetric formulation, representative numerical examples illustrating the performance of the proposed formulation are presented. It is shown that the non-symmetric family may over or underestimate the energy required to create a discontinuity, as this effect is related with the total length of the discontinuity, fact that is not noticed when the discontinuity path is a straight line.
Keywords: Variational formulation, strong discontinuity, embedded discontinuities, strain localization.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1769594 Challenges to Technological Advancement in Economically Weak Countries: An Assessment of the Nigerian Educational Situation
Authors: Iyabosola B. Oronti, Adeoluwawale A. Adewusi, Israel O. Megbowon
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Nigeria is considered as one of the many countries in sub-Saharan Africa with a weak economy and gross deficiencies in technology and engineering. Available data from international monitoring and regulatory organizations show that technology is pivotal to determining the economic strengths of nations all over the world. Education is critical to technology acquisition, development, dissemination and adaptation. Thus, this paper seeks to critically assess and discuss issues and challenges facing technological advancement in Nigeria, particularly in the education sector, and also proffers solutions to resuscitate the Nigerian education system towards achieving national technological and economic sustainability such that Nigeria can compete favourably with other technologicallydriven economies of the world in the not-too-distant future.Keywords: Economically weak countries, education, globalization and competition, technological advancement.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3517593 DQ Analysis of 3D Natural Convection in an Inclined Cavity Using an Velocity-Vorticity Formulation
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In this paper, the differential quadrature method is applied to simulate natural convection in an inclined cubic cavity using velocity-vorticity formulation. The numerical capability of the present algorithm is demonstrated by application to natural convection in an inclined cubic cavity. The velocity Poisson equations, the vorticity transport equations and the energy equation are all solved as a coupled system of equations for the seven field variables consisting of three velocities, three vorticities and temperature. The coupled equations are simultaneously solved by imposing the vorticity definition at boundary without requiring the explicit specification of the vorticity boundary conditions. Test results obtained for an inclined cubic cavity with different angle of inclinations for Rayleigh number equal to 103, 104, 105 and 106 indicate that the present coupled solution algorithm could predict the benchmark results for temperature and flow fields. Thus, it is convinced that the present formulation is capable of solving coupled Navier-Stokes equations effectively and accurately.
Keywords: Natural convection, velocity-vorticity formulation, differential quadrature (DQ).
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1570592 Viscosity Model for Predicting the Power Output from Ocean Salinity and Temperature Energy Conversion System (OSTEC) Part 1: Theoretical Formulation
Authors: Ag. S. Abd. Hamid, S. K. Lee, J. Dayou, R. Yusoff, F. Sulaiman
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The mixture between two fluids of different salinity has been proven to capable of producing electricity in an ocean salinity energy conversion system known as hydrocratic generator. The system relies on the difference between the salinity of the incoming fresh water and the surrounding sea water in the generator. In this investigation, additional parameter is introduced which is the temperature difference between the two fluids; hence the system is known as Ocean Salinity and Temperature Energy Conversion System (OSTEC). The investigation is divided into two papers. This first paper of Part 1 presents the theoretical formulation by considering the effect of fluid dynamic viscosity known as Viscosity Model and later compares with the conventional formulation which is Density Model. The dynamic viscosity model is used to predict the dynamic of the fluids in the system which in turns gives the analytical formulation of the potential power output that can be harvested.
Keywords: Buoyancy, density, frictional head loss, kinetic power, viscosity.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1868591 A Novel Logarithmic Current-Controlled Current Amplifier (LCCA)
Authors: Karama M. AL-Tamimi, Munir A. Al-Absi
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A new OTA-based logarithmic-control variable gain current amplifier (LCCA) is presented. It consists of two Operational Transconductance Amplifier (OTA) and two PMOS transistors biased in weak inversion region. The circuit operates from 0.6V DC power supply and consumes 0.6 μW. The linear-dB controllable output range is 43 dB with maximum error less than 0.5dB. The functionality of the proposed design was confirmed using HSPICE in 0.35μm CMOS process technology.Keywords: LCCA, OTA, Logarithmic, VGA, Weak inversion, Current-mode
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2017590 In Vivo Evaluation of Stable Cream Containing Flavonoids on Hydration and TEWL of Human Skin
Authors: Haji M Shoaib Khan, Naveed Akhtar, Fatima Rasool, Barkat Ali Khan, Tariq Mahmood, Muhammad Shuaib Khan
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Antioxidants contribute to endogenous photoprotection and are important for the maintenance of skin health. The study was carried out to compare the skin hydration and transepidermal water loss (TEWL) effects of a stable cosmetic preparation containing flavonoids, following two applications a day over a period of tenth week. The skin trans-epidermal water loss and skin hydration effect was measured at the beginning and up to the end of study period of ten weeks. Any effect produced was measured by Corneometer and TEWA meter (Non-invasive probe). Two formulations were developed for this study design. Formulation one the control formulation in which no apple juice extract( Flavonoids) was incorporated while second one was the active formulation in which the apple juice extract (3%) containing flavonoids was incorporated into water in oil emulsion using Abil EM 90 as an emulsifier. Stable formulations (control and Active) were applied on human cheeks (n = 12) for a study period of 10 weeks. Result of each volunteer of skin hydration and TEWL was measured by corneometer and TEWA meter. By using ANOVA and Paired sample t test as a statistical evaluation, result of both base and formulation were compared. Statistical significant results (p≤0.05) were observed regarding skin hydration and TEWL when two creams, control and Formulation were compared. It showed that desired formulation (Active) may have interesting application as an active moisturizing cream on healthy skin.Keywords: Apple juice extract, TEWL, Corneometer, flavonoids.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2692589 An Adaptive Least-squares Mixed Finite Element Method for Pseudo-parabolic Integro-differential Equations
Authors: Zilong Feng, Hong Li, Yang Liu, Siriguleng He
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In this article, an adaptive least-squares mixed finite element method is studied for pseudo-parabolic integro-differential equations. The solutions of least-squares mixed weak formulation and mixed finite element are proved. A posteriori error estimator is constructed based on the least-squares functional and the posteriori errors are obtained.
Keywords: Pseudo-parabolic integro-differential equation, least squares mixed finite element method, adaptive method, a posteriori error estimates.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1317588 Formulation of Extended-Release Gliclazide Tablet Using a Mathematical Model for Estimation of Hypromellose
Authors: Farzad Khajavi, Farzaneh Jalilfar, Faranak Jafari, Leila Shokrani
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Formulation of gliclazide in the form of extended-release tablet in 30 and 60 mg dosage forms was performed using hypromellose (HPMC K4M) as a retarding agent. Drug-release profiles were investigated in comparison with references Diamicron MR 30 and 60 mg tablets. The effect of size of powder particles, the amount of hypromellose in formulation, hardness of tablets, and also the effect of halving the tablets were investigated on drug release profile. A mathematical model which describes hypromellose behavior in initial times of drug release was proposed for the estimation of hypromellose content in modified-release gliclazide 60 mg tablet. This model is based on erosion of hypromellose in dissolution media. The model is applicable to describe release profiles of insoluble drugs. Therefore, by using dissolved amount of drug in initial times of dissolution and the model, the amount of hypromellose in formulation can be predictable. The model was used to predict the HPMC K4M content in modified-release gliclazide 30 mg and extended-release quetiapine 200 mg tablets.
Keywords: Hypromellose, gliclazide, drug release, modified-release tablet, mathematical model.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2301587 Developing Research Involving Different Species: Opportunities and Empirical Foundations
Authors: A. V. Varfolomeeva, N. S. Tkachenko, A. G. Tishchenko
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In this study, we addressed the problem of weak validity, implausible results, and inaccurate reporting in psychological research on different species. The theoretical basis of the study was the systems-evolutionary approach (SEA). We assumed that the root of the problem is the values and attitudes of the researchers (in particular anthropomorphism and anthropocentrism). The first aim of the study was the formulation of a research design that avoids this problem. Based on a literature review, we concluded that such design, amongst other things, should include methodics with playful components. The second aim was to conduct a series of studies on the differences in the formation of instrumental skill in rats raised and housed in different environments. As a result, we revealed that there are contradictions between some of the statements of SEA, so that it is not possible to choose one of the alternative hypotheses. We suggested that in order to get out of this problem, it is necessary to modify these provisions by aligning them with the attitude of multicentrism.
Keywords: epistemological attitudes, experimental design, validity, psychological structure, learning
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 422586 Nonlinear Analysis of Shear Wall Using Finite Element Model
Authors: M. A. Ghorbani, M. Pasbani Khiavi, F. Rezaie Moghaddam
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In the analysis of structures, the nonlinear effects due to large displacement, large rotation and materially-nonlinear are very important and must be considered for the reliable analysis. The non-linear fmite element analysis has potential as usable and reliable means for analyzing of civil structures with the availability of computer technology. In this research the large displacements and materially nonlinear behavior of shear wall is presented with developing of fmite element code using the standard Galerkin weighted residual formulation. Two-dimensional plane stress model was carried out to present the shear wall response. Total Lagangian formulation, which is computationally more effective, is used in the formulation of stiffness matrices and the Newton-Raphson method is applied for the solution of nonlinear transient equations. The details of the program formulation are highlighted and the results of the analyses are presented, along with a comparison of the response of the structure with Ansys software results. The presented model in this paper can be developed for nonlinear analysis of civil engineering structures with different material behavior and complicated geometry.
Keywords: Finite element, large displacements, materially nonlinear, shear wall.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1751585 Numerical Simulation of Fluid Structure Interaction Using Two-Way Method
Authors: Samira Laidaoui, Mohammed Djermane, Nazihe Terfaya
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The fluid-structure coupling is a natural phenomenon which reflects the effects of two continuums: fluid and structure of different types in the reciprocal action on each other, involving knowledge of elasticity and fluid mechanics. The solution for such problems is based on the relations of continuum mechanics and is mostly solved with numerical methods. It is a computational challenge to solve such problems because of the complex geometries, intricate physics of fluids, and complicated fluid-structure interactions. The way in which the interaction between fluid and solid is described gives the largest opportunity for reducing the computational effort. In this paper, a problem of fluid structure interaction is investigated with two-way coupling method. The formulation Arbitrary Lagrangian-Eulerian (ALE) was used, by considering a dynamic grid, where the solid is described by a Lagrangian formulation and the fluid by a Eulerian formulation. The simulation was made on the ANSYS software.
Keywords: ALE, coupling, FEM, fluid-structure interaction, one-way method, two-way method.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1511