Search results for: Vibration control
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 4068

Search results for: Vibration control

1548 Influence of Cell-free Proteins in the Nucleation of CaCO3 Crystals in Calcified Endoskeleton

Authors: M. Azizur Rahman, Tamotsu Oomori

Abstract:

Calcite aCalcite and aragonite are the two common polymorphs of CaCO3 observed as biominerals. It is universal that the sea water contents a high Mg2+ (50mM) relative to Ca2+ (10mM). In vivo crystallization, Mg2+ inhibits calcite formation. For this reason, stony corals skeleton may be formed only aragonite crystals in the biocalcification. It is special in case of soft corals of which formed only calcite crystal; however, this interesting phenomenon, still uncharacterized in the marine environment, has been explored in this study using newly purified cell-free proteins isolated from the endoskeletal sclerites of soft coral. By recording the decline of pH in vitro, the control of CaCO3 nucleation and crystal growth by the cellfree proteins was revealed. Using Atomic Force Microscope, here we find that these endoskeletal cell-free proteins significantly design the morphological shape in the molecular-scale kinetics of crystal formation and those proteins act as surfactants to promote ion attachment at calcite steps.nd aragonite are the two common polymorphs of CaCO3 observed as biominerals. It is universal that the sea water contents a high Mg2+ (50mM) relative to Ca2+ (10mM). In vivo crystallization, Mg2+ inhibits calcite formation. For this reason, stony corals skeleton may be formed only aragonite crystals in the biocalcification. It is special in case of soft corals of which formed only calcite crystal; however, this interesting phenomenon, still uncharacterized in the marine environment, has been explored in this study using newly purified cell-free proteins isolated from the endoskeletal sclerites of soft coral. By recording the decline of pH in vitro, the control of CaCO3 nucleation and crystal growth by the cell-free proteins was revealed. Using Atomic Force Microscope, here we find that these endoskeletal cell-free proteins significantly design the morphological shape in the molecular-scale kinetics of crystal formation and those proteins act as surfactants to promote ion attachment at calcite steps. KeywordsBiomineralization, Calcite, Cell-free protein, Soft coral

Keywords: Biomineralization, Calcite, Cell-free protein, Soft coral

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1547 Low Power Consuming Electromagnetic Actuators for Pulsed Pilot Stages

Authors: M. Honarpardaz, Z. Zhang, J. Derkx, A. Trangärd, J. Larsson

Abstract:

Pilot stages are one of the most common positioners and regulators in industry. In this paper, we present two novel concepts for pilot stages with low power consumption to regulate a pneumatic device. Pilot 1, first concept, is designed based on a conventional frame core electro-magnetic actuator and a leaf spring to control the air flow and pilot 2 has an axisymmetric actuator and spring made of non-oriented electrical steel. Concepts are simulated in a system modeling tool to study their dynamic behavior. Both concepts are prototyped and tested. Experimental results are comprehensively analyzed and compared. The most promising concept that consumes less than 8 mW is highlighted and presented.

Keywords: Electro-magnetic actuator, multidisciplinary system, low power consumption, pilot stage.

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1546 Tracking Trajectory of a Cable-Driven Robot for Lower Limb Rehabilitation

Authors: Hachmia Faqihi, Maarouf Saad, Khalid Benjelloun, Mohammed Benbrahim, M. Nabil Kabbaj

Abstract:

This paper investigates and presents a cable-driven robot to lower limb rehabilitation use in sagittal plane. The presented rehabilitation robot is used for a trajectory tracking in joint space. The paper covers kinematic and dynamic analysis, which reveals the tensionability of the used cables as being the actuating source to provide a rehabilitation exercises of the human leg. The desired trajectory is generated to be used in the control system design in joint space. The obtained simulation results is showed to be efficient in this kind of application.

Keywords: Cable-driven multibody system, computed-torque controller, lower limb rehabilitation, tracking trajectory.

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1545 Analysis of Control by Flattening of the Welded Tubes

Authors: Hannachi Med Tahar, H. Djebaili, B. Daheche

Abstract:

In this approach, we have tried to describe the flattening of welded tubes, and its experimental application. The test is carried out at the (National product processing company dishes and tubes production). Usually, the final products (tubes) undergo a series of non-destructive inspection online and offline welding, and obviously destructive mechanical testing (bending, flattening, flaring, etc.). For this and for the purpose of implementing the flattening test, which applies to the processing of round tubes in other forms, it took four sections of welded tubes draft (before stretching hot) and welded tubes finished (after drawing hot and annealing), it was also noted the report 'health' flattened tubes must not show or crack or tear. The test is considered poor if it reveals a lack of ductility of the metal.

Keywords: Flattening, destructive testing, tube drafts, finished tube, Castem 2001.

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1544 A Grid Synchronization Method Based on Adaptive Notch Filter for SPV System with Modified MPPT

Authors: Priyanka Chaudhary, M. Rizwan

Abstract:

This paper presents a grid synchronization technique based on adaptive notch filter for SPV (Solar Photovoltaic) system along with MPPT (Maximum Power Point Tracking) techniques. An efficient grid synchronization technique offers proficient detection of various components of grid signal like phase and frequency. It also acts as a barrier for harmonics and other disturbances in grid signal. A reference phase signal synchronized with the grid voltage is provided by the grid synchronization technique to standardize the system with grid codes and power quality standards. Hence, grid synchronization unit plays important role for grid connected SPV systems. As the output of the PV array is fluctuating in nature with the meteorological parameters like irradiance, temperature, wind etc. In order to maintain a constant DC voltage at VSC (Voltage Source Converter) input, MPPT control is required to track the maximum power point from PV array. In this work, a variable step size P & O (Perturb and Observe) MPPT technique with DC/DC boost converter has been used at first stage of the system. This algorithm divides the dPpv/dVpv curve of PV panel into three separate zones i.e. zone 0, zone 1 and zone 2. A fine value of tracking step size is used in zone 0 while zone 1 and zone 2 requires a large value of step size in order to obtain a high tracking speed. Further, adaptive notch filter based control technique is proposed for VSC in PV generation system. Adaptive notch filter (ANF) approach is used to synchronize the interfaced PV system with grid to maintain the amplitude, phase and frequency parameters as well as power quality improvement. This technique offers the compensation of harmonics current and reactive power with both linear and nonlinear loads. To maintain constant DC link voltage a PI controller is also implemented and presented in this paper. The complete system has been designed, developed and simulated using SimPower System and Simulink toolbox of MATLAB. The performance analysis of three phase grid connected solar photovoltaic system has been carried out on the basis of various parameters like PV output power, PV voltage, PV current, DC link voltage, PCC (Point of Common Coupling) voltage, grid voltage, grid current, voltage source converter current, power supplied by the voltage source converter etc. The results obtained from the proposed system are found satisfactory.

Keywords: Solar photovoltaic systems, MPPT, voltage source converter, grid synchronization technique.

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1543 A New Approach for Recoverable Timestamp Ordering Schedule

Authors: Hassan M. Najadat

Abstract:

A new approach for timestamp ordering problem in serializable schedules is presented. Since the number of users using databases is increasing rapidly, the accuracy and needing high throughput are main topics in database area. Strict 2PL does not allow all possible serializable schedules and so does not result high throughput. The main advantages of the approach are the ability to enforce the execution of transaction to be recoverable and the high achievable performance of concurrent execution in central databases. Comparing to Strict 2PL, the general structure of the algorithm is simple, free deadlock, and allows executing all possible serializable schedules which results high throughput. Various examples which include different orders of database operations are discussed.

Keywords: Concurrency control, schedule, timestamp, transaction.

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1542 Investigation of the Effects of Sampling Frequency on the THD of 3-Phase Inverters Using Space Vector Modulation

Authors: Khattab Ibrahim Al Qaisi, Nicholas Bowring

Abstract:

This paper presents the simulation results of the effects of sampling frequency on the total harmonic distortion (THD) of three-phase inverters using the space vector pulse width modulation (SVPWM) and space vector control (SVC) algorithms. The relationship between the variables was studied using curve fitting techniques, and it has been shown that, for 50 Hz inverters, there is an exponential relation between the sampling frequency and THD up to around 8500 Hz, beyond which the performance of the model becomes irregular, and there is an negative exponential relation between the sampling frequency and the marginal improvement to the THD. It has also been found that the performance of SVPWM is better than that of SVC with the same sampling frequency in most frequency range, including the range where the performance of the former is irregular.

Keywords: SVPWM, THD, DC-AC Inverter, Sampling Frequency.

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1541 SIP Authentication Scheme using ECDH

Authors: Aytunc Durlanik, Ibrahim Sogukpinar

Abstract:

SIP (Session Initiation Protocol), using HTML based call control messaging which is quite simple and efficient, is being replaced for VoIP networks recently. As for authentication and authorization purposes there are many approaches and considerations for securing SIP to eliminate forgery on the integrity of SIP messages. On the other hand Elliptic Curve Cryptography has significant advantages like smaller key sizes, faster computations on behalf of other Public Key Cryptography (PKC) systems that obtain data transmission more secure and efficient. In this work a new approach is proposed for secure SIP authentication by using a public key exchange mechanism using ECC. Total execution times and memory requirements of proposed scheme have been improved in comparison with non-elliptic approaches by adopting elliptic-based key exchange mechanism.

Keywords: SIP, Elliptic Curve Cryptography, voice over IP.

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1540 Investigation of the Effect of Nano-Alumina Particles on Adsorption Property of Acrylic Fiber

Authors: Mehdi Ketabchi, Shallah Alijanlo

Abstract:

The flue gas from fossil fuels combustion contains harmful pollutants dangerous for human health and environment. One of the air pollution control methods to restrict the emission of these pollutants is based on using the nanoparticle in adsorption process. In the present research, gamma nano-alumina particle is added to polyacrylonitrile (PAN) polymer through simple loading method, and the adsorption capacity of the wet spun fiber is investigated. The results of exposure the fiber to the acid gases including SO2, CO, NO2, NO, and CO2 show the noticeable increase of gas adsorption capacity on fiber contains nanoparticle. The research has been conducted in Acrylic II Plant of Polyacryl Iran Corporation.

Keywords: Acrylic fiber, adsorbent, wet spun, polyacryl company, gamma nano-alumina.

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1539 Speedup of Data Vortex Network Architecture

Authors: Qimin Yang

Abstract:

In this paper, 3X3 routing nodes are proposed to provide speedup and parallel processing capability in Data Vortex network architectures. The new design not only significantly improves network throughput and latency, but also eliminates the need for distributive traffic control mechanism originally embedded among nodes and the need for nodal buffering. The cost effectiveness is studied by a comparison study with the previously proposed 2- input buffered networks, and considerable performance enhancement can be achieved with similar or lower cost of hardware. Unlike previous implementation, the network leaves small probability of contention, therefore, the packet drop rate must be kept low for such implementation to be feasible and attractive, and it can be achieved with proper choice of operation conditions.

Keywords: Data Vortex, Packet Switch, Interconnection network, deflection, Network-on-chip

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1538 Investigation of Chaotic Behavior in DC-DC Converters

Authors: Sajid Iqbal, Masood Ahmed, Suhail Aftab Qureshi

Abstract:

DC-DC converters are widely used in regulated switched mode power supplies and in DC motor drive applications. There are several sources of unwanted nonlinearity in practical power converters. In addition, their operation is characterized by switching that gives birth to a variety of nonlinear dynamics. DC-DC buck and boost converters controlled by pulse-width modulation (PWM) have been simulated. The voltage waveforms and attractors obtained from the circuit simulation have been studied. With the onset of instability, the phenomenon of subharmonic oscillations, quasi-periodicity, bifurcations, and chaos have been observed. This paper is mainly motivated by potential contributions of chaos theory in the design, analysis and control of power converters, in particular and power electronics circuits, in general.

Keywords: Buck converter, boost converter, period- doubling, chaos, bifurcation, strange attractor.

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1537 Modeling and Simulation of PSM DC-DC Buck Converter

Authors: Ramamurthy S, Vanaja Ranjan P

Abstract:

A DC-to-DC converter for applications involving a source with widely varying voltage conditions with loads requiring constant voltage from full load down to no load is presented. The switching regulator considered is a Buck converter with Pulse Skipping Modulation control whereby pulses applied to the switch are blocked or released on output voltage crossing a predetermined value. Results of the study on the performance of regulator circuit are presented. The regulator regulates over a wide input voltage range with slightly higher ripple content and good transient response. Input current spectrum indicates a good EMI performance with crowding of components at low frequency range.

Keywords: DC/DC Converter, Pulse Skipping Modulation, Buckregulator, Modulation Factor, Electromagnetic Interference

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1536 An Automated High Pressure Differential Thermal Analysis System for Phase Transformation Studies

Authors: T. K. Mondal, N C Shivaprakash

Abstract:

A piston cylinder based high pressure differential thermal analyzer system is developed to investigate phase transformations, melting, glass transitions, crystallization behavior of inorganic materials, glassy systems etc., at ambient to 4 GPa and at room temperature to 1073 K. The pressure is calibrated by the phase transition of bismuth and ytterbium and temperature is calibrated by using thermocouple data chart. The system developed is calibrated using benzoic acid, ammonium nitrate and it has a pressure and temperature control of ± 8.9 x 10 -4 GPa , ± 2 K respectively. The phase transition of Asx Te100-x chalcogenides, ferrous oxide and strontium boride are studied using the indigenously developed system.

Keywords: double stage crystallization, Phase transition, Quasi hydrostatic, Rigidity percolation

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1535 Nutritional Value of Rabbit Meat after Contamination with 1,1-Dimethylhydrazine

Authors: Balgabay Sadepovich Maikanov, Laura Tyulegenovna Auteleyeva, Seidenova Simbat Polatbekovna

Abstract:

In this article reduced nutritional value of the rabbits’ meat at 1, 1 dimethylhydrazine experimental toxicosis is shown. The assay was performed on liquid chromatograph SHIMADZU LC-20 Prominence (Japan) with fluorometric and spectrophotometric detector. This research has revealed that samples of rabbit meat of the experimental group had significant differences from the control group:in amino acids concentration from 1.2% to 9.1%; vitamin concentration from 11.2% to 60.5%, macro – minerals concentration from 17.4% to 78.1% and saturated fatty acids concentration from 17,1% to 34.5%, respectively. The decrease in the chemical composition of rabbits’ meat at 1,1 dimethylhydrazine toxicosis may be due to changes in the internal processes associated with impaired metabolic homeostasis of animals.

Keywords: 1, 1-dimethylhydrazine, metabolic homeostasis, nutritional value, rabbit meat.

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1534 Comparing the Durability of Saudi Silica Sands for Use in Foundry Processing

Authors: Mahdi Alsagour, Sam Ramrattan

Abstract:

This paper was developed to investigate two types of sands from the Kingdom of Saudi Arabia (KSA) for potential use in the global metal casting industry. Four types of sands were selected for study, two of the sand systems investigated are natural sands from the KSA. The third sand sample is a heat processed synthetic sand and the last sample is commercially available US silica sand that is used as a control in the study. The purpose of this study is to define the durability of the four sand systems selected for foundry usage. Additionally, chemical analysis of the sand systems is presented before and after elevated temperature exposure. Results show that Saudi silica sands are durable and can be used in foundry processing.

Keywords: Alternative molding media, foundry sand, reclamation, silica sand, specialty sand.

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1533 An Analytical Comparison between Open Loop, PID and Fuzzy Logic Based DC-DC Boost Convertor

Authors: Muhammad Mujtaba Asad, Razali Bin Hassan, Fahad Sherwani

Abstract:

This paper explains about the voltage output for DC to DC boost converter between open loop, PID controller and fuzzy logic controller through Matlab Simulink. Simulink input voltage was set at 12V and the voltage reference was set at 24V. The analysis on the deviation of voltage resulted that the difference between reference voltage setting and the output voltage is always lower. Comparison between open loop, PID and FLC shows that, the open loop circuit having a bit higher on the deviation of voltage. The PID circuit boosts for FLC has a lesser deviation of voltage and proved that it is such a better performance on control the deviation of voltage during the boost mode.

Keywords: Boost Convertors, Power Electronics, PID, Fuzzy logic, Open loop.

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1532 An Adaptive Setting of Frequency Relay with Consideration on Load and Power System Dynamics

Authors: J. Mirzaei, H. Kazemi Kargar

Abstract:

This paper presents a new approach for setting frequency relays based on the dynamic of power system. A simplified model of the power system based on the load-frequency control loop will be developed to be used instead of the complete model of the power system. The effects of the equipments and their responses on the frequency variations of the power plant will be investigated and then a method for adaptive settings of frequency relays will be explained. The proposed method will be investigated by analyzing a simplified model of a power plant by MATLAB software.

Keywords: Adaptive Settings, Frequency Relay (FR), PowerSystem Dynamics, SFR model.

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1531 Optimization of Real Time Measured Data Transmission, Given the Amount of Data Transmitted

Authors: Michal Kopcek, Tomas Skulavik, Michal Kebisek, Gabriela Krizanova

Abstract:

The operation of nuclear power plants involves continuous monitoring of the environment in their area. This monitoring is performed using a complex data acquisition system, which collects status information about the system itself and values of many important physical variables e.g. temperature, humidity, dose rate etc. This paper describes a proposal and optimization of communication that takes place in teledosimetric system between the central control server responsible for the data processing and storing and the decentralized measuring stations, which are measuring the physical variables. Analyzes of ongoing communication were performed and consequently the optimization of the system architecture and communication was done.

Keywords: Communication protocol, transmission optimization, data acquisition.

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1530 Stability Verification for Bilateral Teleoperation System with Variable Time Delay

Authors: M. Sallam, A. Ramadan, M. Fanni, M. Abdellatif

Abstract:

Time delay in bilateral teleoperation system was introduced as a sufficient reason to make the system unstable or certainly degrade the system performance. In this paper, simulations and experimental results of implementing p-like control scheme, under different ranges of variable time delay, will be presented to verify a certain criteria, which guarantee the system stability and position tracking. The system consists of two Phantom premium 1.5A devices. One of them acts as a master and the other acts as a slave. The study includes deriving the Phantom kinematic and dynamic model, establishing the link between the two Phantoms over Simulink in Matlab, and verifying the stability criteria with simulations and real experiments.

Keywords: bilateral teleoperation, Phantom premium 1.5, varying time delay

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1529 Ultrafast Transistor Laser Containing Graded Index Separate Confinement Heterostructure

Authors: Mohammad Hosseini

Abstract:

Ultrafast transistor laser investigated here has the graded index separate confinement heterostructure (GRIN-SCH) in its base region. Resonance-free optical frequency response with -3 dB bandwidth of more than 26 GHz has been achieved for a single quantum well transistor laser by using graded index layers of AlξGa1-ξAs (ξ: 0.1→0) in the left side of quantum well and AlξGa1-ξAs (ξ: 0.05→0) in the right side of quantum well. All required parameters, including quantum well and base transit time, optical confinement factor and spontaneous recombination lifetime, have been calculated using a self-consistent charge control model.

Keywords: Transistor laser, ultrafast, GRIN-SCH, -3db optical bandwidth, AlξGa1-ξAs.

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1528 The Care Management Network as an Effective Intervention in Mitigating the Risks of Hypertension

Authors: Feng-Chuan Pan, Fang-Yue Liu

Abstract:

Hospitals in southern Hualien teamed with the Hypertension Joint Care Network. Working with the network, the team provided a special designed health education to the individual who had been identified as a hypertension patient in the outpatient department. Some metabolism improvements achieved. This is a retrospective study by purposively taking 106 patients from a hospital between 2008 and 2010. Records of before and after education intervention of the objects was collected and analyzed to see the how the intervention affected the patients- hypertension control via clinical parameter monitoring. The results showed that the clinical indicators, the LDL-C, the cholesterol and the systolic blood pressure were significantly improved. The study provides evidence for the effectiveness of the network in controlling hypertension.

Keywords: hypertension, joint care management network, cardiovascular diseases, metabolic syndrome.

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1527 The Concentration Analysis of CO2 Using ALOHA Code for Kuosheng Nuclear Power Plant

Authors: W. S. Hsu, Y. Chiang, H. C. Chen, J. R. Wang, S. W. Chen, J. H. Yang, C. Shih

Abstract:

Not only radiation materials, but also the normal chemical material stored in the power plant can cause a risk to the residents. In this research, the ALOHA code was used to perform the concentration analysis under the CO2 storage burst or leakage conditions for Kuosheng nuclear power plant (NPP). The Final Safety Analysis Report (FSAR) and data were used in this study. Additionally, the analysis results of ALOHA code were compared with the R.G. 1.78 failure criteria in order to confirm the control room habitability. The comparison results show that the ALOHA result for burst case was 0.923 g/m3 which was below the criteria. However, the ALOHA results for leakage case was 11.3 g/m3.

Keywords: BWR, ALOHA, habitability, Kuosheng.

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1526 A Comparison of Shunt Active Power Filter Control Methods under Non-Sinusoidal and Unbalanced Voltage Conditions

Authors: H. Abaali, M. T. Lamchich, M. Raoufi

Abstract:

There are a variety of reference current identification methods, for the shunt active power filter (SAPF), such as the instantaneous active and reactive power, the instantaneous active and reactive current and the synchronous detection method are evaluated and compared under ideal, non sinusoidal and unbalanced voltage conditions. The SAPF performances, for the investigated identification methods, are tested for a non linear load. The simulation results, using Matlab Power System Blockset Toolbox from a complete structure, are presented and discussed.

Keywords: Shunt active power filter, Current perturbation, Non sinusoidal and unbalanced voltage conditions.

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1525 Development of an Efficient CVT using Electromecanical System

Authors: A. A. Shafie, M. H. Ali

Abstract:

Continuously variable transmission (CVT) is a type of automatic transmission that can change the gear ratio to any arbitrary setting within the limits. The most common type of CVT operates on a pulley system that allows an infinite variability between highest and lowest gears with no discrete steps. However, the current CVT system with hydraulic actuation method suffers from the power loss. It needs continuous force for the pulley to clamp the belt and hold the torque resulting in large amount of energy consumption. This study focused on the development of an electromechanical actuated control CVT to eliminate the problem that faced by the existing CVT. It is conducted with several steps; computing and selecting the appropriate sizing for stroke length, lead screw system and etc. From the visual observation it was found that the CVT system of this research is satisfactory.

Keywords: CVT, Hydraulic Actuator, Discrete shifts, Electromechanical system, Lead screws.

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1524 Adaptive Notch Filter for Harmonic Current Mitigation

Authors: T. Messikh, S. Mekhilef, N. A. Rahim

Abstract:

This paper presents an effective technique for harmonic current mitigation using an adaptive notch filter (ANF) to estimate current harmonics. The proposed filter consists of multiple units of ANF connected in parallel structure; each unit is governed by two ordinary differential equations. The frequency estimation is carried out based on the output of these units. The simulation and experimental results show the ability of the proposed tracking scheme to accurately estimate harmonics. The proposed filter was implemented digitally in TMS320F2808 and used in the control of hybrid active power filter (HAPF). The theoretical expectations are verified and demonstrated experimentally.

Keywords: Adaptive notch filter, Active power filter, harmonic filtering, Time varying frequency.

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1523 Reducing the Short Circuit Levels in Kuwait Transmission Network (A Case Study)

Authors: Mahmoud Gilany, Wael Al-Hasawi

Abstract:

Preliminary studies on Kuwait high voltage transmission system show significant increase in the short circuit level at some of the grid substations and some generating stations. This increase results from the growth in the power transmission systems in size and complexity. New generating stations are expected to be added to the system within the next few years. This paper describes the study analysis performed to evaluate the available and potential solutions to control SC levels in Kuwait power system. It also presents a modified planning of the transmission network in order to fulfill this task.

Keywords: Short circuit current, network splitting, fault current limiter, power transmission planning.

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1522 Evolution, Tendencies and Impact of Standardization of Input/Output Platforms in Full Scale Simulators for Training Power Plant Operators

Authors: Zabre Eric, Román Rafael

Abstract:

This article presents the evolution and technological changes implemented on the full scale simulators developed by the Simulation Department of the Instituto de Investigaciones Eléctricas1 (Mexican Electric Research Institute) and located at different training centers around the Mexican territory, and allows US to know the last updates, basically from the input/output view point, of the current simulators at some facilities of the electrical sector as well as the compatible industry of the electrical manufactures and industries such as Comision Federal de Electricidad (CFE*, The utility Mexican company). Tendencies of these developments and impact within the operators- scope are also presented.

Keywords: Control room, communication protocol, instructor console, modeling, controller, training simulator

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1521 Extension of Fish Shelf Life by Ozone Treatment

Authors: Behrouz Mosayebi Dehkordi, Neda Zokaie

Abstract:

The shelf life of fish was extended using disinfection properties of ozone. For this purpose, Trout specimens were exposed to ozone in the aqueous media for two hours and their microbial growth and biochemical properties were measured over time. Microbial growth of ozone treated fish was significantly slower than control sample, resulting in lower counts of bacteria. According to the biochemical tests; ozone treatment had no negative effects on fat, protein and humidity of fish. Peroxide and TVN (Total Volatile Nitrogen) measurements showed that treatment by ozone increased the trout shelf life from 4 days to 6 days. According to the sensory analysis, no changes were observed in color or flavor of the ozone treated trout.

Keywords: Fish, Ozone, Shelf life, Trout.

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1520 Study on Liquid Nitrogen Gravity Circulation Loop for Cryopumps in Large Space Simulator

Authors: Weiwei Shan, Wenjing Ding, Juan Ning, Chao He, Zijuan Wang

Abstract:

Gravity circulation loop for the cryopumps of the space simulator is introduced, and two phase mathematic model of flow heat transfer is analyzed as well. Based on this model, the liquid nitrogen (LN2) gravity circulation loop including its equipment and layout is designed and has served as LN2 feeding system for cryopumps in one large space simulator. With the help of control software and human machine interface, this system can be operated flexibly, simply, and automatically under four conditions. When running this system, the results show that the cryopumps can be cooled down and maintained under the required temperature, 120 K.

Keywords: Cryopumps, gravity circulation loop, liquid nitrogen, two-phase.

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1519 Quality Based Approach for Efficient Biologics Manufacturing

Authors: Takashi Kaminagayoshi, Shigeyuki Haruyama

Abstract:

To improve the manufacturing efficiency of biologics, such as antibody drugs, a quality engineering framework was designed. Within this framework, critical steps and parameters in the manufacturing process were studied. Identification of these critical steps and critical parameters allows a deeper understanding of manufacturing capabilities, and suggests to process development department process control standards based on actual manufacturing capabilities as part of a PDCA (plan-do-check-act) cycle. This cycle can be applied to each manufacturing process so that it can be standardized, reducing the time needed to establish each new process.

Keywords: Antibody drugs, biologics, manufacturing efficiency, PDCA cycle, quality engineering.

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