Search results for: Fluid Structural Interaction
2839 Simulated Annealing Application for Structural Optimization
Authors: Farhad Kolahan, M. Hossein Abolbashari, Samaeddin Mohitzadeh
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Several methods are available for weight and shape optimization of structures, among which Evolutionary Structural Optimization (ESO) is one of the most widely used methods. In ESO, however, the optimization criterion is completely case-dependent. Moreover, only the improving solutions are accepted during the search. In this paper a Simulated Annealing (SA) algorithm is used for structural optimization problem. This algorithm differs from other random search methods by accepting non-improving solutions. The implementation of SA algorithm is done through reducing the number of finite element analyses (function evaluations). Computational results show that SA can efficiently and effectively solve such optimization problems within short search time.Keywords: Simulated annealing, Structural optimization, Compliance, C.V. product.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19552838 Seismic Performance Evaluation of the Composite Structural System with Separated Gravity and Lateral Resistant Systems
Authors: Zi-Ang Li, Mu-Xuan Tao
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During the process of the industrialization of steel structure housing, a composite structural system with separated gravity and lateral resistant systems has been applied in engineering practices, which consists of composite frame with hinged beam-column joints, steel brace and RC shear wall. As an attempt in steel structural system area, seismic performance evaluation of the separated composite structure is important for further application in steel housing. This paper focuses on the seismic performance comparison of the separated composite structural system and traditional steel frame-shear wall system under the same inter-story drift ratio (IDR) provision limit. The same architectural layout of a high-rise building is designed as two different structural systems at the same IDR level, and finite element analysis using pushover method is carried out. Static pushover analysis implies that the separated structural system exhibits different lateral deformation mode and failure mechanism with traditional steel frame-shear wall system. Different indexes are adopted and discussed in seismic performance evaluation, including IDR, safe factor (SF), shear wall damage, etc. The performance under maximum considered earthquake (MCE) demand spectrum shows that the shear wall damage of two structural systems are similar; the separated composite structural system exhibits less plastic hinges; and the SF index value of the separated composite structural system is higher than the steel frame shear wall structural system.
Keywords: Finite element analysis, seismic performance evaluation, separated composite structural system, static pushover analysis.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 5702837 Finite Element Modeling of Rotating Mixing of Toothpaste
Authors: Inamullah Bhatti, Ahsanullah Baloch, Khadija Qureshi
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The objective of this research is to examine the shear thinning behaviour of mixing flow of non-Newtonian fluid like toothpaste in the dissolution container with rotating stirrer. The problem under investigation is related to the chemical industry. Mixing of fluid is performed in a cylindrical container with rotating stirrer, where stirrer is eccentrically placed on the lid of the container. For the simulation purpose the associated motion of the fluid is considered as revolving of the container, with stick stirrer. For numerical prediction, a time-stepping finite element algorithm in a cylindrical polar coordinate system is adopted based on semi-implicit Taylor-Galerkin/pressure-correction scheme. Numerical solutions are obtained for non-Newtonian fluids employing power law model. Variations with power law index have been analysed, with respect to the flow structure and pressure drop.
Keywords: finite element simulation, mixing fluid, rheology, rotating flow, toothpaste
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 22552836 Effect of Treadmill Exercise on Fluid Intelligence in Early Adults: Electroencephalogram Study
Authors: Ladda Leungratanamart, Seree Chadcham
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Fluid intelligence declines along with age, but it can be developed. For this reason, increasing fluid intelligence in young adults can be possible. This study examined the effects of a two-month treadmill exercise program on fluid intelligence. The researcher designed a treadmill exercise program to promote cardiorespiratory fitness. Thirty-eight healthy voluntary students from the Boromarajonani College of Nursing, Chon Buri were assigned randomly to an exercise group (n=18) and a control group (n=20). The experiment consisted of three sessions: The baseline session consisted of measuring the VO2max, electroencephalogram and behavioral response during performed the Raven Progressive Matrices (RPM) test, a measure of fluid intelligence. For the exercise session, an experimental group exercises using treadmill training at 60 % to 80 % maximum heart rate for 30 mins, three times per week, whereas the control group did not exercise. For the following two sessions, each participant was measured the same as baseline testing. The data were analyzed using the t-test to examine whether there is significant difference between the means of the two groups. The results showed that the mean VO2 max in the experimental group were significantly more than the control group (p<.05), suggesting a two-month treadmill exercise program can improve fluid intelligence. When comparing the behavioral data, it was found that experimental group performed RPM test more accurately and faster than the control group. Neuroelectric data indicated a significant increase in percentages of alpha band ERD (%ERD) at P3 and Pz compared to the pre-exercise condition and the control group. These data suggest that a two-month treadmill exercise program can contribute to the development of cardiorespiratory fitness which influences an increase fluid intelligence. Exercise involved in cortical activation in difference brain areas.
Keywords: Treadmill exercise, fluid intelligence, raven progressive matrices test, %ERD of upper Alpha band.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 24432835 A General Model for Amino Acid Interaction Networks
Authors: Omar Gaci, Stefan Balev
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In this paper we introduce the notion of protein interaction network. This is a graph whose vertices are the protein-s amino acids and whose edges are the interactions between them. Using a graph theory approach, we identify a number of properties of these networks. We compare them to the general small-world network model and we analyze their hierarchical structure.Keywords: interaction network, protein structure, small-world network.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 15772834 Marangoni Instability in a Fluid Layer with Insoluble Surfactant
Authors: Ainon Syazana Ab. Hamid, Seripah Awang Kechil, Ahmad Sukri Abd. Aziz
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The Marangoni convective instability in a horizontal fluid layer with the insoluble surfactant and nondeformable free surface is investigated. The surface tension at the free surface is linearly dependent on the temperature and concentration gradients. At the bottom surface, the temperature conditions of uniform temperature and uniform heat flux are considered. By linear stability theory, the exact analytical solutions for the steady Marangoni convection are derived and the marginal curves are plotted. The effects of surfactant or elasticity number, Lewis number and Biot number on the marginal Marangoni instability are assessed. The surfactant concentration gradients and the heat transfer mechanism at the free surface have stabilizing effects while the Lewis number destabilizes fluid system. The fluid system with uniform temperature condition at the bottom boundary is more stable than the fluid layer that is subjected to uniform heat flux at the bottom boundary.Keywords: Analytical solutions, Marangoni Instability, Nondeformable free surface, Surfactant.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 18312833 Physical Properties of Uranium Dinitride UN2 by Using Density Functional Theory (DFT and DFT+U)
Authors: T. Zergoug, S.H. Abaidia, A. Nedjar, M. Y. Mokeddem
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Physical properties of uranium dinitride (UN2) were investigated in detail using first principle calculations based on density functional theory (DFT). To study the strong correlation effects due to 5f uranium valence electrons, the on-site coulomb interaction correction U via the Hubbard-like term (DFT+U) was employed. The UN2 structural, mechanical and thermodynamic properties were calculated within DFT and Various U of DFT+U approach. The Perdew–Burke–Ernzerhof (PBE.5.2) version of the generalized gradient approximation (GGA) is used to describe the exchange-correlation with the projector-augmented wave (PAW) pseudo potentials. A comparative study shows that results are improved by using the Hubbard formalism for a certain U value correction like the structural parameter. For some physical properties the variation versus Hubbard-U is strong like Young modulus but for others it is weakly noticeable such as bulk modulus. We noticed also that from U=7.5 eV, elastic results don’t agree with the cubic cell because of the C44 values which turn out to be negative.
Keywords: Ab initio, bulk modulus, DFT, DFT + U.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 25572832 Numerical Study of Fluid Mixing in a Grooved Micro-Channel with Wavy Sidewalls
Authors: Yu-Sin Lin, Chih-Yang Wu, Yung-Ching Chu
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In this work, we perform numerical simulation of fluid mixing in a floor-grooved micro-channel with wavy sidewalls which may impose perturbation on the helical flow induced by the slanted grooves on the channel floor. The perturbation is caused by separation vortices in the recesses of the wavy-walled channel as the Reynolds number is large enough. The results show that the effects of the wavy sidewalls of the present micromixer on the enhancement of fluid mixing increase with the increase of Reynolds number. The degree of mixing increases with the increase of the corrugation angle, until the angle is greater than 45 degrees. Besides, the pumping pressure of the micromixer increases with the increase of the corrugation angle monotonically. Therefore, we would suggest setting the corrugation angle of the wavy sidewalls to be 45 degrees.
Keywords: Fluid mixing, grooved channel, microfluidics, separation vortex.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 22252831 Predictions of Dynamic Behaviors for Gas Foil Bearings Operating at Steady-State Based on Multi-Physics Coupling Computer Aided Engineering Simulations
Authors: Tai Yuan Yu, Pei-Jen Wang
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A simulation scheme of rotational motions for predictions of bump-type gas foil bearings operating at steady-state is proposed. The scheme is based on multi-physics coupling computer aided engineering packages modularized with computational fluid dynamic model and structure elasticity model to numerically solve the dynamic equation of motions of a hydrodynamic loaded shaft supported by an elastic bump foil. The bump foil is assumed to be modelled as infinite number of Hookean springs mounted on stiff wall. Hence, the top foil stiffness is constant on the periphery of the bearing housing. The hydrodynamic pressure generated by the air film lubrication transfers to the top foil and induces elastic deformation needed to be solved by a finite element method program, whereas the pressure profile applied on the top foil must be solved by a finite element method program based on Reynolds Equation in lubrication theory. As a result, the equation of motions for the bearing shaft are iteratively solved via coupling of the two finite element method programs simultaneously. In conclusion, the two-dimensional center trajectory of the shaft plus the deformation map on top foil at constant rotational speed are calculated for comparisons with the experimental results.
Keywords: Computational fluid dynamics, fluid structure interaction multi-physics simulations, gas foil bearing, load capacity.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 5852830 Protein-Protein Interaction Detection Based on Substring Sensitivity Measure
Authors: Nazar Zaki, Safaai Deris, Hany Alashwal
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Detecting protein-protein interactions is a central problem in computational biology and aberrant such interactions may have implicated in a number of neurological disorders. As a result, the prediction of protein-protein interactions has recently received considerable attention from biologist around the globe. Computational tools that are capable of effectively identifying protein-protein interactions are much needed. In this paper, we propose a method to detect protein-protein interaction based on substring similarity measure. Two protein sequences may interact by the mean of the similarities of the substrings they contain. When applied on the currently available protein-protein interaction data for the yeast Saccharomyces cerevisiae, the proposed method delivered reasonable improvement over the existing ones.
Keywords: Protein-Protein Interaction, support vector machine, feature extraction, pairwise alignment, Smith-Waterman score.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19362829 Natural Convection Boundary Layer Flow of a Viscoelastic Fluid on Solid Sphere with Newtonian Heating
Authors: A.R.M. Kasim, N.F. Mohammad, Aurangzaib, S. Sharidan
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The present paper considers the steady free convection boundary layer flow of a viscoelastic fluid on solid sphere with Newtonian heating. The boundary layer equations are an order higher than those for the Newtonian (viscous) fluid and the adherence boundary conditions are insufficient to determine the solution of these equations completely. Thus, the augmentation an extra boundary condition is needed to perform the numerical computational. The governing boundary layer equations are first transformed into non-dimensional form by using special dimensionless group and then solved by using an implicit finite difference scheme. The results are displayed graphically to illustrate the influence of viscoelastic K and Prandtl Number Pr parameters on skin friction, heat transfer, velocity profiles and temperature profiles. Present results are compared with the published papers and are found to concur very well.Keywords: boundary layer flow, Newtonian heating, sphere, viscoelastic fluid.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 24072828 Performances Analysis of the Pressure and Production of an Oil Zone by Simulation of the Flow of a Fluid through the Porous Media
Authors: Makhlouf Mourad, Medkour Mihoub, Bouchher Omar, Messabih Sidi Mohamed, Benrachedi Khaled
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This work is the modeling and simulation of fluid flow (liquid) through porous media. This type of flow occurs in many situations of interest in applied sciences and engineering, fluid (oil) consists of several individual substances in pure, single-phase flow is incompressible and isothermal. The porous medium is isotropic, homogeneous optionally, with the rectangular format and the flow is two-dimensional. Modeling of hydrodynamic phenomena incorporates Darcy's law and the equation of mass conservation. Correlations are used to model the density and viscosity of the fluid. A finite volume code is used in the discretization of differential equations. The nonlinearity is treated by Newton's method with relaxation coefficient. The results of the simulation of the pressure and the mobility of liquid flowing through porous media are presented, analyzed, and illustrated.
Keywords: Darcy equation, middle porous, continuity equation, Peng Robinson equation, mobility.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 7812827 Project and Experiment-Based Fluid Dynamics Education
Authors: Etsuo Morishita
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This paper presents the project and experiment-based fluid dynamics education in Meisei University, a private institution in Tokyo, Japan. We pay attention not only to the basic engineering courses but also to the practical aspect of engineering experience. So, we prepare courses called the Projects from I to VI. The Projects I and II are designed for the first year, III and IV are designated for the second year, V and VI are prepared for the third year, respectively. Each supervisor is responsible for two of these projects every year. When students take the Project V and VI at the third year, we automatically assume that these students will join the lab of the project for the graduation thesis. We would like to show our experience in the Project I in the summer term, 2016. In this project, we introduce a traction flight vehicle called Cat Flyer. This is a kind of a kite towed by a car for example. This is very similar to parasailing, but flight is possible even on the roads. Experiments in mechanical engineering education are also very important, and we would like to explain our course on centrifugal pump, venture, and orifice. Although these are described in detail in the text books of fluid dynamics, it is still crucial to have practical experiments as a student.
Keywords: Aerodynamics, experiment, fluid dynamics, project.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 14892826 Selecting Negative Examples for Protein-Protein Interaction
Authors: Mohammad Shoyaib, M. Abdullah-Al-Wadud, Oksam Chae
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Proteomics is one of the largest areas of research for bioinformatics and medical science. An ambitious goal of proteomics is to elucidate the structure, interactions and functions of all proteins within cells and organisms. Predicting Protein-Protein Interaction (PPI) is one of the crucial and decisive problems in current research. Genomic data offer a great opportunity and at the same time a lot of challenges for the identification of these interactions. Many methods have already been proposed in this regard. In case of in-silico identification, most of the methods require both positive and negative examples of protein interaction and the perfection of these examples are very much crucial for the final prediction accuracy. Positive examples are relatively easy to obtain from well known databases. But the generation of negative examples is not a trivial task. Current PPI identification methods generate negative examples based on some assumptions, which are likely to affect their prediction accuracy. Hence, if more reliable negative examples are used, the PPI prediction methods may achieve even more accuracy. Focusing on this issue, a graph based negative example generation method is proposed, which is simple and more accurate than the existing approaches. An interaction graph of the protein sequences is created. The basic assumption is that the longer the shortest path between two protein-sequences in the interaction graph, the less is the possibility of their interaction. A well established PPI detection algorithm is employed with our negative examples and in most cases it increases the accuracy more than 10% in comparison with the negative pair selection method in that paper.Keywords: Interaction graph, Negative training data, Protein-Protein interaction, Support vector machine.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 17012825 The Role of Ionic Strength and Mineral Size to Zeta Potential for the Adhesion of P. putida to Mineral Surfaces
Authors: M. Z. Fathiah, R. G. Edyvean
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Electrostatic interaction energy (ΔEEDL) is a part of the Extended Derjaguin-Landau-Verwey-Overbeek (XDLVO) theory, which, together with van der Waals (ΔEVDW) and acid base (ΔEAB) interaction energies, has been extensively used to investigate the initial adhesion of bacteria to surfaces. Electrostatic or electrical double layer interaction energy is considerably affected by surface potential; however it cannot be determined experimentally and is usually replaced by zeta (ζ) potential via electrophoretic mobility. This paper focusses on the effect of ionic concentration as a function of pH and the effect of mineral grain size on ζ potential. It was found that both ionic strength and mineral grain size play a major role in determining the value of ζ potential for the adhesion of P. putida to hematite and quartz surfaces. Higher ζ potential values lead to higher electrostatic interaction energies and eventually to higher total XDLVO interaction energy resulting in bacterial repulsion.
Keywords: XDLVO, Electrostatic interaction energy, zeta potential, P. putida, mineral.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 26042824 Industrial Waste Monitoring
Authors: Khairuddin Bin Osman, Ngo Boon Kiat, A. Hamid Bin hamidon, Khairul Azha Bin A. Aziz, Hazli Rafis Bin Abdul Rahman, Mazran Bin Esro
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Conventional industrial monitoring systems are tedious, inefficient and the at times integrity of the data is unreliable. The objective of this system is to monitor industrial processes specifically the fluid level which will measure the instantaneous fluid level parameter and respond by text messaging the exact value of the parameter to the user when being enquired by a privileged access user. The development of the embedded program code and the circuit for fluid level measuring are discussed as well. Suggestions for future implementations and efficient remote monitoring works are included.Keywords: Industrial monitoring system, text messaging, embedded programming.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16822823 Seismic Performance of Masonry Buildings in Algeria
Authors: F. Lazzali, S. Bedaoui
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Structural performance and seismic vulnerability of masonry buildings in Algeria are investigated in this paper. Structural classification of such buildings is carried out regarding their structural elements. Seismicity of Algeria is briefly discussed. Then vulnerability of masonry buildings and their failure mechanisms in the Boumerdes earthquake (May, 2003) are examined.Keywords: Masonry building, seismic deficiencies, vulnerability classes
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 23602822 Soliton Interaction in Multi-Core Optical Fiber: Application to WDM System
Authors: S. Arun Prakash, V. Malathi, M. S. Mani Rajan
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The analytical bright two soliton solution of the 3- coupled nonlinear Schrödinger equations with variable coefficients in birefringent optical fiber is obtained by Darboux transformation method. To the design of ultra-speed optical devices, Soliton interaction and control in birefringence fiber is investigated. Lax pair is constructed for N coupled NLS system through AKNS method. Using two-soliton solution, we demonstrate different interaction behaviors of solitons in birefringent fiber depending on the choice of control parameters. Our results shows that interactions of optical solitons have some specific applications such as construction of logic gates, optical computing, soliton switching, and soliton amplification in wavelength division multiplexing (WDM) system.Keywords: Optical soliton, soliton interaction, soliton switching, WDM.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 21572821 Natural Convection in Wavy-Wall Cavities Filled with Power-Law Fluid
Authors: Cha’o-Kuang Chen, Ching-Chang Cho
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This paper investigates the natural convection heat transfer performance in a complex-wavy-wall cavity filled with power-law fluid. In performing the simulations, the continuity, Cauchy momentum and energy equations are solved subject to the Boussinesq approximation using a finite volume method. The simulations focus specifically on the effects of the flow behavior index in the power-law model and the Rayleigh number on the flow streamlines, isothermal contours and mean Nusselt number within the cavity. The results show that pseudoplastic fluids have a better heat transfer performance than Newtonian or dilatant fluids. Moreover, it is shown that for Rayleigh numbers greater than Ra=103, the mean Nusselt number has a significantly increase as the flow behavior index is decreased.
Keywords: Non-Newtonian fluid, Power-law fluid, Natural convection, Heat transfer enhancement, Cavity, Wavy wall.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19902820 Touching Interaction: An NFC-RFID Combination
Authors: Eduardo Álvarez, Gerardo Quiroga, Jorge Orozco, Gabriel Chavira
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AmI proposes a new way of thinking about computers, which follows the ideas of the Ubiquitous Computing vision of Mark Weiser. In these, there is what is known as a Disappearing Computer Initiative, with users immersed in intelligent environments. Hence, technologies need to be adapted so that they are capable of replacing the traditional inputs to the system by embedding these in every-day artifacts. In this work, we present an approach, which uses Radiofrequency Identification (RFID) and Near Field Communication (NFC) technologies. In the latter, a new form of interaction appears by contact. We compare both technologies by analyzing their requirements and advantages. In addition, we propose using a combination of RFID and NFC.
Keywords: Touching interaction, ambient intelligence, NFC, RFID.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16262819 Structural Performance of a Timber-Concrete Bridge Prototype
Authors: Pedro Gutemberg de Alcântara Segundinho, José Antonio Matthiesen, Marcelo Rodrigo Carreira
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Timber-concrete structures were recently introduced in Brazil as a viable option for bridge construction on side roads. Binding between timber and concrete is fundamentally important to assure the rigidity and performance of this structural system. The objective of this study was to assess the structural performance of a timber-concrete bridge prototype with width of 170cm and span of 400cm, whose binding among timber beams and concrete slabs was made with metal pins, obtained from CA 50 construction steel bars of 12.5mm diameter. It was possible to conclude, from the results obtained experimentally in laboratory, that the timber-concrete bridge prototype showed a good structural performance. This structural system provides an economical, rapid implementation solution, which may be used on side roads, favoring regional integration and agricultural production flow.
Keywords: Binding, bridge prototype, timber and concrete
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 21412818 New Insight into Fluid Mechanics of Lorenz Equations
Authors: Yu-Kai Ting, Jia-Ying Tu, Chung-Chun Hsiao
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New physical insights into the nonlinear Lorenz equations related to flow resistance is discussed in this work. The chaotic dynamics related to Lorenz equations has been studied in many papers, which is due to the sensitivity of Lorenz equations to initial conditions and parameter uncertainties. However, the physical implication arising from Lorenz equations about convectional motion attracts little attention in the relevant literature. Therefore, as a first step to understand the related fluid mechanics of convectional motion, this paper derives the Lorenz equations again with different forced conditions in the model. Simulation work of the modified Lorenz equations without the viscosity or buoyancy force is discussed. The time-domain simulation results may imply that the states of the Lorenz equations are related to certain flow speed and flow resistance. The flow speed of the underlying fluid system increases as the flow resistance reduces. This observation would be helpful to analyze the coupling effects of different fluid parameters in a convectional model in future work.
Keywords: Galerkin method, Lorenz equations, Navier-Stokes equations.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 23092817 Analysis of DNA-Recognizing Enzyme Interaction using Deaminated Lesions
Authors: Seung Pil Pack
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Deaminated lesions were produced via nitrosative oxidation of natural nucleobases; uracul (Ura, U) from cytosine (Cyt, C), hypoxanthine (Hyp, H) from adenine (Ade, A), and xanthine (Xan, X) and oxanine (Oxa, O) from guanine (Gua, G). Such damaged nucleobases may induce mutagenic problems, so that much attentions and efforts have been poured on the revealing of their mechanisms in vivo or in vitro. In this study, we employed these deaminated lesions as useful probes for analysis of DNA-binding/recognizing proteins or enzymes. Since the pyrimidine lesions such as Hyp, Oxa and Xan are employed as analogues of guanine, their comparative uses are informative for analyzing the role of Gua in DNA sequence in DNA-protein interaction. Several DNA oligomers containing such Hyp, Oxa or Xan substituted for Gua were designed to reveal the molecular interaction between DNA and protein. From this approach, we have got useful information to understand the molecular mechanisms of the DNA-recognizing enzymes, which have not ever been observed using conventional DNA oligomer composed of just natural nucleobases.
Keywords: Deaminated lesion, DNA-protein interaction, DNA-recognizing enzymes
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 12912816 Generalized Stokes’ Problems for an Incompressible Couple Stress Fluid
Authors: M.Devakar, T.K.V.Iyengar
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In this paper, we investigate the generalized Stokes’ problems for an incompressible couple stress fluid. Analytical solution of the governing equations is obtained in Laplace transform domain for each problem. A standard numerical inversion technique is used to invert the Laplace transform of the velocity in each case. The effect of various material parameters on velocity is discussed and the results are presented through graphs. It is observed that, the results are in tune with the observation of V.K.Stokes in connection with the variation of velocity in the flow between two parallel plates when the top one is moving with constant velocity and the bottom one is at rest.
Keywords: Couple stress fluid, Generalized Stokes’ problems, Laplace transform, Numerical inversion
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 32372815 Seismic Rehabilitation of R/C Buildings Designed with Earlier Technical Standards
Authors: Stefano Sorace, Gloria Terenzi
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The seismic rehabilitation designs of two reinforced concrete school buildings, representative of a wide stock of similar edifices designed under earlier editions of the Italian Technical Standards, are presented in this paper. The mutual retrofit solution elaborated for the two buildings consists in the incorporation of a dissipative bracing system including pressurized fluid viscous springdampers as passive protective devices. The mechanical parameters, layouts and locations selected for the constituting elements of the system; the architectural renovation projects developed to properly incorporate the structural interventions and improve the appearance of the buildings; highlights of the installation works already completed in one of the two structures; and a synthesis of the performance assessment analyses carried out in original and rehabilitated conditions, are illustrated. The results of the analyses show a remarkable enhancement of the seismic response capacities of both structures. This allows reaching the high performance objectives postulated in the retrofit designs with much lower costs and architectural intrusion as compared to traditional rehabilitation interventions designed for the same objectives.Keywords: Seismic rehabilitation, R/C structures, performance analysis, dissipative braces, fluid viscous dampers.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16422814 Ground Heat Exchanger Modeling Developed for Energy Flows of an Incompressible Fluid
Authors: Paul Christodoulides, Georgios Florides, Panayiotis Pouloupatis, Vassilios Messaritis, Lazaros Lazari
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Ground-source heat pumps achieve higher efficiencies than conventional air-source heat pumps because they exchange heat with the ground that is cooler in summer and hotter in winter than the air environment. Earth heat exchangers are essential parts of the ground-source heat pumps and the accurate prediction of their performance is of fundamental importance. This paper presents the development and validation of a numerical model through an incompressible fluid flow, for the simulation of energy and temperature changes in and around a U-tube borehole heat exchanger. The FlexPDE software is used to solve the resulting simultaneous equations that model the heat exchanger. The validated model (through a comparison with experimental data) is then used to extract conclusions on how various parameters like the U-tube diameter, the variation of the ground thermal conductivity and specific heat and the borehole filling material affect the temperature of the fluid.Keywords: U-tube borehole, energy flow, incompressible fluid, numerical model
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20022813 Analytical and Experimental Methods of Design for Supersonic Two-Stage Ejectors
Authors: S. Daneshmand, C. Aghanajafi, A. Bahrami
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In this paper the supersonic ejectors are experimentally and analytically studied. Ejector is a device that uses the energy of a fluid to move another fluid. This device works like a vacuum pump without usage of piston, rotor or any other moving component. An ejector contains an active nozzle, a passive nozzle, a mixing chamber and a diffuser. Since the fluid viscosity is large, and the flow is turbulent and three dimensional in the mixing chamber, the numerical methods consume long time and high cost to analyze the flow in ejectors. Therefore this paper presents a simple analytical method that is based on the precise governing equations in fluid mechanics. According to achieved analytical relations, a computer code has been prepared to analyze the flow in different components of the ejector. An experiment has been performed in supersonic regime 1.52812 Damage Evolution of Underground Structural Reinforced Concrete Small-Scale Static-Loading Experiments
Authors: Ahmed Mohammed Youssef Mohammed, Mohammad Reza Okhovat, Koichi Maekawa
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Small-scale RC models of both piles and tunnel ducts were produced as mockups of reality and loaded under soil confinement conditionsto investigate the damage evolution of structural RC interacting with soil. Experimental verifications usinga 3D nonlinear FE analysis program called COM3D, which was developed at the University of Tokyo, are introduced. This analysis has been used in practice for seismic performance assessment of underground ducts and in-ground LNG storage tanks in consideration of soil-structure interactionunder static and dynamic loading. Varying modes of failure of RCpilessubjected to different magnitudes of soil confinement were successfully reproduced in the proposed small-scale experiments and numerically simulated as well. Analytical simulation was applied to RC tunnel mockups under a wide variety of depth and soil confinement conditions, and reasonable matching was confirmed.Keywords: Soil-Structure Interaction, RC pile, RC Tunnel
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 22842811 Passive Seismic Energy Dissipation Mechanisms for Smart Green Structural System (SGSS)
Authors: Daniel Y. Abebe, Dongyoung Lim, Gyumyong Gwak, Jaehyouk Choi
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The design philosophy of building structure has been changing time to time. The reason for this is because of an increase of human inertest, an improved building materials and technology that will impact how we live, to speed up construction period and natural effect which includes earthquake disasters and environmental effect. One technique which takes in to account the above case is using a prefabricable structural system. In which each and every structural element is designed and prefabricated and assembled on a site so that the construction speed is increased and the environmental impact is also enhanced. This system has an immense advantage such as: reduce construction cost, reusable, recyclable, speed up construction period and less environmental effect. In this study, it is tried to present some of the developed and evaluated structural elements of building structures.
Keywords: Eccentrically braced frame, Natural disaster, Prefabricable structural, Removable link, SGSS.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19412810 Computational Fluid Dynamics Expert System using Artificial Neural Networks
Authors: Gonzalo Rubio, Eusebio Valero, Sven Lanzan
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The design of a modern aircraft is based on three pillars: theoretical results, experimental test and computational simulations. As a results of this, Computational Fluid Dynamic (CFD) solvers are widely used in the aeronautical field. These solvers require the correct selection of many parameters in order to obtain successful results. Besides, the computational time spent in the simulation depends on the proper choice of these parameters. In this paper we create an expert system capable of making an accurate prediction of the number of iterations and time required for the convergence of a computational fluid dynamic (CFD) solver. Artificial neural network (ANN) has been used to design the expert system. It is shown that the developed expert system is capable of making an accurate prediction the number of iterations and time required for the convergence of a CFD solver.Keywords: Artificial Neural Network, Computational Fluid Dynamics, Optimization
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2956