Search results for: risk treatment
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 2394

Search results for: risk treatment

684 Laser Doppler Flowmetry in Diagnostics of Vascular Lesions in Lower Extremities

Authors: Petr V. Vasilev, Eduard V. Volkov, Alexej N. Godok, Alexej A, Grischschuk, Vitalij A. Rybalchenko

Abstract:

Laser Doppler flowmetry is a modern method of noninvasive microcirculation investigation. The aim of our study was to use this method in the examination of patients with secondary lymphedema of the lower extremities and obliterating atherosclerosis of lower extremities. In the analysis of the amplitude-frequency spectrum of secondary lymphedema patients we have identified remarkable changes. To describe the changes we used a special amplitude rate. In both of patients groups this rate was significally (p<0.05) different with the control group. So the marker phenomena of the amplitude-frequency spectrum of the LDF signal were identified. It is suggested that there is a limfodynamics contribution to the formation of the output signal of laser Doppler flowmetry. These data have fundamental meaning and are interesting for practical medicine, as they give an opportunity to further developments for the use of laser Doppler flowmetry in the diagnostics and monitoring the effectiveness of the treatment.

Keywords: laser Doppler flowmetry, secondary lymphedema of the lower extremities, obliterating atherosclerosis, non-invasive diagnostics.

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683 An Advanced Approach Based on Artificial Neural Networks to Identify Environmental Bacteria

Authors: Mauro Giacomini, Stefania Bertone, Federico Caneva Soumetz, Carmelina Ruggiero

Abstract:

Environmental micro-organisms include a large number of taxa and some species that are generally considered nonpathogenic, but can represent a risk in certain conditions, especially for elderly people and immunocompromised individuals. Chemotaxonomic identification techniques are powerful tools for environmental micro-organisms, and cellular fatty acid methyl esters (FAME) content is a powerful fingerprinting identification technique. A system based on an unsupervised artificial neural network (ANN) was set up using the fatty acid profiles of standard bacterial strains, obtained by gas-chromatography, used as learning data. We analysed 45 certified strains belonging to Acinetobacter, Aeromonas, Alcaligenes, Aquaspirillum, Arthrobacter, Bacillus, Brevundimonas, Enterobacter, Flavobacterium, Micrococcus, Pseudomonas, Serratia, Shewanella and Vibrio genera. A set of 79 bacteria isolated from a drinking water line (AMGA, the major water supply system in Genoa) were used as an example for identification compared to standard MIDI method. The resulting ANN output map was found to be a very powerful tool to identify these fresh isolates.

Keywords: Cellular fatty acid methyl esters, environmental bacteria, gas-chromatography, unsupervised ANN.

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682 Possible Protective Effect of Kombucha Tea Ferment on Cadmium Chloride Induced Liver and Kidney Damage in Irradiated Rats

Authors: Nashwa Kamel Ibrahim

Abstract:

Kombucha Tea Ferment (KT), was given to male albino rats, (1ml/Kg of body weight), via gavages, during 2 weeks before intraperitoneal administration of 3.5 mg/Kg body weight CdCl2 and/or whole body γ-irradiation with 4Gy, and during 4 weeks after each treatment. Hepatic and nephritic pathological changes included significant increases of serum alanine transaminase (ALT), aspartate transaminase (AST), and alkaline phosphatase (ALP) activities, and creatinine and urea contents with significant decrease in serum total antioxidant capacity (TAC). Increase in oxidative stress markers in liver and kidney tissues expressed by significant increase in malondialdehyde (MDA) and nitric oxide (NO) contents associated to significant depletion in superoxide dismutase (SOD) and catalase (CAT) activities, and reduced glutathione (GSH) content were recorded. KT administration results in recovery of all the pathological changes. It could be concluded that KT might protect liver and kidney from oxidative damage induced by exposure to cadmium and/ or γ-irradiation.

Keywords: Cadmium, Kombucha, radiation, rats

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681 Privacy in New Mobile Payment Protocol

Authors: Tan Soo Fun, Leau Yu Beng, Rozaini Roslan, Habeeb Saleh Habeeb

Abstract:

The increasing development of wireless networks and the widespread popularity of handheld devices such as Personal Digital Assistants (PDAs), mobile phones and wireless tablets represents an incredible opportunity to enable mobile devices as a universal payment method, involving daily financial transactions. Unfortunately, some issues hampering the widespread acceptance of mobile payment such as accountability properties, privacy protection, limitation of wireless network and mobile device. Recently, many public-key cryptography based mobile payment protocol have been proposed. However, limited capabilities of mobile devices and wireless networks make these protocols are unsuitable for mobile network. Moreover, these protocols were designed to preserve traditional flow of payment data, which is vulnerable to attack and increase the user-s risk. In this paper, we propose a private mobile payment protocol which based on client centric model and by employing symmetric key operations. The proposed mobile payment protocol not only minimizes the computational operations and communication passes between the engaging parties, but also achieves a completely privacy protection for the payer. The future work will concentrate on improving the verification solution to support mobile user authentication and authorization for mobile payment transactions.

Keywords: Mobile Network Operator, Mobile payment protocol, Privacy, Symmetric key.

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680 Statistical Modeling for Permeabilization of a Novel Yeast Isolate for β-Galactosidase Activity Using Organic Solvents

Authors: Shweta Kumari, Parmjit S. Panesar, Manab B. Bera

Abstract:

The hydrolysis of lactose using β-galactosidase is one of the most promising biotechnological applications, which has wide range of potential applications in food processing industries. However, due to intracellular location of the yeast enzyme, and expensive extraction methods, the industrial applications of enzymatic hydrolysis processes are being hampered. The use of permeabilization technique can help to overcome the problems associated with enzyme extraction and purification of yeast cells and to develop the economically viable process for the utilization of whole cell biocatalysts in food industries. In the present investigation, standardization of permeabilization process of novel yeast isolate was carried out using a statistical model approach known as Response Surface Methodology (RSM) to achieve maximal b-galactosidase activity. The optimum operating conditions for permeabilization process for optimal β-galactosidase activity obtained by RSM were 1:1 ratio of toluene (25%, v/v) and ethanol (50%, v/v), 25.0 oC temperature and treatment time of 12 min, which displayed enzyme activity of 1.71 IU /mg DW.

Keywords: β-galactosidase, optimization, permeabilization, response surface methodology, yeast.

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679 Optimal Portfolio Selection in a DC Pension with Multiple Contributors and the Impact of Stochastic Additional Voluntary Contribution on the Optimal Investment Strategy

Authors: Edikan E. Akpanibah, Okwigbedi Oghen’Oro

Abstract:

In this paper, we studied the optimal portfolio selection in a defined contribution (DC) pension scheme with multiple contributors under constant elasticity of variance (CEV) model and the impact of stochastic additional voluntary contribution on the investment strategies. We assume that the voluntary contributions are stochastic and also consider investments in a risk free asset and a risky asset to increase the expected returns of the contributing members. We derived a stochastic differential equation which consists of the members’ monthly contributions and the invested fund and obtained an optimized problem with the help of Hamilton Jacobi Bellman equation. Furthermore, we find an explicit solution for the optimal investment strategy with stochastic voluntary contribution using power transformation and change of variables method and the corresponding optimal fund size was obtained. We discussed the impact of the voluntary contribution on the optimal investment strategy with numerical simulations and observed that the voluntary contribution reduces the optimal investment strategy of the risky asset.

Keywords: DC pension fund, Hamilton-Jacobi-Bellman, optimal investment strategies, power transformation method, stochastic, voluntary contribution.

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678 Are Adolescent Girls More Depressive than Adolescent Boys in Turkey?

Authors: Hatice Odacı

Abstract:

Depression is a serious mental health problem that affects people of all ages, including children and adolescents. Studies showed that female gender is one of the risk factors may influence the development of depression in adolescents. However, some of the studies from Turkey suggested that gender does not lead to any significant difference in the youth depression level. Therefore, the presented study investigated whether girls differ from boys in respect of depression. The association between genders and test scores for the adolescents in a population of primary and secondary school students was also evaluated. The study was consisting of 254 adolescents (122 boys and 132 girls) with a mean age of 13.86±1.43 (Mean±SD) ranging from 12-16 years. Psychological assessment was performed using Children-s Depression Inventory (CDI). Chi-square and Student-s t-test statistics were employed to analyze the data. The mean of the CDI scores of the girls were higher than boys- CDI scores (t = -4.580, p = 0.001). Higher ratio appeared for the girls when they compared with boy group-s depression levels using a CDI cut-off point of 19 (p = 0.001, Odds Ratio = 2,603). The findings of the present study suggested that adolescent girls have high level of depression than adolescent boys aged between 12-16 years in Turkey. Although some studies reported that there is no any differences depression level between adolescent boys and girls in Turkey, result of the present study showed that adolescent girls have high level of depression than adolescent boys in Turkey.

Keywords: Depression, Adolescent, Turkey, Female Gender, Male Gender.

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677 Packaging the Alkaloids of Cinchona Bark in Combination with Etoposide in Polymeric Micelles Nanoparticles

Authors: Diky Mudhakir, Satrialdi, Sukmadjaja Asyarie, Yeyet C. Sumirtapura

Abstract:

Today, cancer remains one of the major diseases that lead to death. The main obstacle in chemotherapy as a main cancer treatment is the toxicity to normal cells due to Multidrug Resistance (MDR) after the use of anticancer drugs. Proposed solution to overcome this problem is the use of MDR efflux inhibitor of cinchona alkaloids which is delivered together with anticancer drugs encapsulated in the form of polymeric nanoparticles. The particles were prepared by the hydration method. The characterization of nanoparticles was particle size, zeta potential, entrapment efficiency and in vitro drug release. Combination nanoparticle size ranged 29-45 nm with a neutral surface charge. Entrapment efficiency was above 87% for the use quinine, quinidine or cinchonidine in combination with etoposide. The release test results exhibited that the cinchona alkaloids release released faster than that of etoposide. Collectively, cinchona alkaloids can be packaged along with etoposide in nanomicelles for better cancer therapy.

Keywords: Cinchona alkaloids, etoposide, MDR efflux inhitor, polymeric nanomicelles.

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676 Anticoagulatory Role of an Ergot Mesylate: Hydergine

Authors: Fareeha A., Irfan Z Qureshi

Abstract:

Thrombosis can be life threatening, necessitating therefore its instant treatment. Hydergine, a nootropic agent is used as a cognition enhancer in stroke patients but relatively little is known about its anti-thrombolytic effect. To investigate this aspect, in vivo and ex vivo experiments were designed and conducted. Three groups of rats were injected 1.5mg, 3.0mg and 4.5mg hydergine intraperitonealy with and without prior exposure to fresh plasma. Positive and negative controls were run in parallel. Animals were sacrificed after 1.5hrs and BT, CT, PT, INR, APTT, plasma calcium levels were estimated. For ex vivo analyses, each 1ml blood aspirated was exposed to 0.1mg, 0.2mg, 0.3mg dose of hydergine with parallel controls. Parameters analyzed were as above. Statistical analysis was through one-way ANOVA. Dunken-s and Tukey-s tests provided intra-group variance. BT, CT, PT, INR and APTT increased while calcium levels dropped significantly (P<0.05). Ex vivo, CT, PT and APTT were elevated while plasma calcium levels lowered significantly (P<0.05). Our study suggests that hydergine may act as a thrombolytic agent but warrants further studies to elucidate this role of ergot mesylates.

Keywords: Hydergine, Coagulation assays, plasma calcium, ergot mesylates, thrombosis.

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675 The Contribution of the PCR-Enzymatic Digestion in the Positive Diagnosis of Proximal Spinal Muscular Atrophy in the Moroccan Population

Authors: H. Merhni, A. Sbiti, I. Ratbi, A. Sefiani

Abstract:

The proximal spinal muscular atrophy (SMA) is a group of neuromuscular disorders characterized by progressive muscle weakness due to the degeneration and loss of anterior motor neurons of the spinal cord. Depending on the age of onset of symptoms and their evolution, four types of SMA, varying in severity, result in a mutations of the SMN gene (survival of Motor neuron). We have analyzed the DNA of 295 patients referred to our genetic counseling; since January 1996 until October 2014; for suspected SMA. The homozygous deletion of exon 7 of the SMN gene was found in 133 patients; of which, 40.6% were born to consanguineous parents. In countries like Morocco, where the frequency of heterozygotes for SMA is high, genetic testing should be offered as first-line and, after careful clinical assessment, especially in newborns and infants with congenital hypotonia unexplained and prognosis compromise. The molecular diagnosis of SMA allows a quick and certainly diagnosis, provide adequate genetic counseling for families at risk and suggest, for couples who want prenatal diagnosis. The analysis of the SMN gene is a perfect example of genetic testing with an excellent cost/benefit ratio that can be of great interest in public health, especially in low-income countries. We emphasize in this work for the benefit of the generalization of molecular diagnosis of SMA by the technique of PCR-enzymatic digestion in other centers in Morocco.

Keywords: Exon7, PCR-digestion, SMA, SMN gene.

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674 Mechanical Properties of D2 Tool Steel Cryogenically Treated Using Controllable Cooling

Authors: A. Rabin, G. Mazor, I. Ladizhenski, R. Z. Shneck

Abstract:

The hardness and hardenability of AISI D2 cold work tool steel with conventional quenching (CQ), deep cryogenic quenching (DCQ) and rapid deep cryogenic quenching heat treatments caused by temporary porous coating based on magnesium sulfate was investigated. Each of the cooling processes was examined from the perspective of the full process efficiency, heat flux in the austenite-martensite transformation range followed by characterization of the temporary porous layer made of magnesium sulfate using confocal laser scanning microscopy (CLSM), surface and core hardness and hardenability using Vickers hardness technique. The results show that the cooling rate (CR) at the austenite-martensite transformation range has a high influence on the hardness of the studied steel.

Keywords: AISI D2, controllable cooling, magnesium sulfate coating, rapid cryogenic heat treatment, temporary porous layer.

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673 Selective Sulfidation of Copper, Zinc and Nickelin Plating Wastewater using Calcium Sulfide

Authors: K. Soya, N. Mihara, D. Kuchar, M. Kubota, H. Matsuda, T. Fukuta

Abstract:

The present work is concerned with sulfidation of Cu, Zn and Ni containing plating wastewater with CaS. The sulfidation experiments were carried out at a room temperature by adding solid CaS to simulated metal solution containing either single-metal of Ni, Zn and Cu, or Ni-Zn-Cu mixture. At first, the experiments were conducted without pH adjustment and it was found that the complete sulfidation of Zn and Ni was achieved at an equimolar ratio of CaS to a particular metal. However, in the case of Cu, a complete copper sulfidation was achieved at CaS to Cu molar ratio of about 2. In the case of the selective sulfidation, a simulated plating solution containing Cu, Zn and Ni at the concentration of 100 mg/dm3 was treated with CaS under various pH conditions. As a result, selective precipitation of metal sulfides was achieved by a sulfidation treatment at different pH values. Further, the precipitation agents of NaOH, Na2S and CaS were compared in terms of the average specific filtration resistance and compressibility coefficients of metal sulfide slurry. Consequently, based on the lowest filtration parameters of the produced metal sulfides, it was concluded that CaS was the most effective precipitation agent for separation and recovery of Cu, Zn and Ni.

Keywords: Calcium sulfide, Plating Wastewater, Filtrationcharacteristics, Heavy metals, Sulfidation.

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672 Gaits Stability Analysis for a Pneumatic Quadruped Robot Using Reinforcement Learning

Authors: Soofiyan Atar, Adil Shaikh, Sahil Rajpurkar, Pragnesh Bhalala, Aniket Desai, Irfan Siddavatam

Abstract:

Deep reinforcement learning (deep RL) algorithms leverage the symbolic power of complex controllers by automating it by mapping sensory inputs to low-level actions. Deep RL eliminates the complex robot dynamics with minimal engineering. Deep RL provides high-risk involvement by directly implementing it in real-world scenarios and also high sensitivity towards hyperparameters. Tuning of hyperparameters on a pneumatic quadruped robot becomes very expensive through trial-and-error learning. This paper presents an automated learning control for a pneumatic quadruped robot using sample efficient deep Q learning, enabling minimal tuning and very few trials to learn the neural network. Long training hours may degrade the pneumatic cylinder due to jerk actions originated through stochastic weights. We applied this method to the pneumatic quadruped robot, which resulted in a hopping gait. In our process, we eliminated the use of a simulator and acquired a stable gait. This approach evolves so that the resultant gait matures more sturdy towards any stochastic changes in the environment. We further show that our algorithm performed very well as compared to programmed gait using robot dynamics.

Keywords: model-based reinforcement learning, gait stability, supervised learning, pneumatic quadruped

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671 The Effect of Pyridoxine and Different Levels of Nitrogen on Physiological Indices of Corn(Zea Mays L.var.sc704)

Authors: Gholamreza Farrokhi, Babak Paykarestan

Abstract:

One field experiment was conducted on corn (Zea mays L.Var. SC 704) to study the effect of three different basic levels of nitrogen (90, 140and 190 Kg/ha as urea) with 0.01% and 0.02% pyridoxine pre-sowing seed soaking for 8 hours. Water-soaked seeds were treated as controled. biomass production was recorded on 45, 70 and 95 days after sowing. Total dry material (TDM), leaf area index (LAI), crop growth rate (CGR), relative growth rate (RGR) and net assimilation rate (NAR) was calculated form 45until 95 days after sowing. Yield and its components such as kernel yield, grain weight, biologic yield, harvest index and protein percentage was measured at harvest. In general, 0.02% pyridoxine and 190 Kg pure nitrogen/ha was shown gave maximum value for growth and yield parameters. N190 + 0.02 % pyridoxine enhanced seed yield and biologic yield by 57.15% and 62.98% compared to 90kg N and water – soaked treatment.

Keywords: Corn, Growth Indices, Nitrogen Levels, Physiological Indices, Pyridoxine.

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670 Hybrid Structure Learning Approach for Assessing the Phosphate Laundries Impact

Authors: Emna Benmohamed, Hela Ltifi, Mounir Ben Ayed

Abstract:

Bayesian Network (BN) is one of the most efficient classification methods. It is widely used in several fields (i.e., medical diagnostics, risk analysis, bioinformatics research). The BN is defined as a probabilistic graphical model that represents a formalism for reasoning under uncertainty. This classification method has a high-performance rate in the extraction of new knowledge from data. The construction of this model consists of two phases for structure learning and parameter learning. For solving this problem, the K2 algorithm is one of the representative data-driven algorithms, which is based on score and search approach. In addition, the integration of the expert's knowledge in the structure learning process allows the obtainment of the highest accuracy. In this paper, we propose a hybrid approach combining the improvement of the K2 algorithm called K2 algorithm for Parents and Children search (K2PC) and the expert-driven method for learning the structure of BN. The evaluation of the experimental results, using the well-known benchmarks, proves that our K2PC algorithm has better performance in terms of correct structure detection. The real application of our model shows its efficiency in the analysis of the phosphate laundry effluents' impact on the watershed in the Gafsa area (southwestern Tunisia).

Keywords: Classification, Bayesian network; structure learning, K2 algorithm, expert knowledge, surface water analysis.

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669 The Importance and Role of Sukuk Marketing as an Islamic Bond in the Economy

Authors: Ilhan Keskin, Hasan Bulent Kantarcı

Abstract:

In this study, one of the tools of Islamic financing known as “Sukuk” a non-interest bearing investment which has started to be implemented in Turkey and the world as a whole is discussed. In order to increase the vitality and efficiency of the economy, by taking lessons from the recent economic crisis new developments in the banking and investment sector are being expanded. The purpose of all investors is to obtain more revenue through the use of capital. The inability of traditional investment tools to meet the expectations of investors and the interest based financial system where one investor benefits at the expense of another there has been the need for a different, reliable and noninterest bearing financial market that is consistent with the Islamic rule. As a result an alternative and more reliable interest free financing tool “Sukuk” rental certificates covering people who are sensitive to Islamic rules, appeal to all segments, hidden remaining capital that contributes to the economy, reduce disparities in income distribution, common risk sharing system of profit and loss sharing has emerged. Today, for the structural countries by examining the state of the world market economy the applicability, enactment and future issues associated with this attractive kind of Islamic finance namely the “Sukuk” market has been explained.

Keywords: Islamic finance, Islamic markets, non-interest bearing, rental certificates.

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668 Detente and Power - Conceptual Determination, Forms and Means of Education at the Preteen Age

Authors: Constantin Pehoiu

Abstract:

The scientific perspective, the practice area of physical education and sports activities improve power capacity in all its forms of expression, being a generator of the research topics. Today theories that strength training athletes and slow down development progress will affect the strength and flexibility are discredited. On the other hand there are sectors and / or samples whose results are sports of the way higher manifestation of power as a result of the composition of the force and velocity, being based in this respect on the systematic and continuous development of both bio-motric capacities said. Training of force for children was and is controversial. Teama de accidentări sau a stopării premature a procesului de creştere a făcut ca în trecut copiii să fie ţinuţi departe de lucrul cu diferite greutăţi.Fear of injury or premature stop the growth process in the past made the children to be kept away from working with different weights. Recent studies have shown that the risk of accidents is relatively small and the strength training can help prevent them. For example, most accidents occur at the level of athletics ligaments and tendons. From this point of view, it can be said that a progressive intervention of force training, optimal design, will help enhancing their process, such as athlete much better prepared to meet training requests and competitions. Preparation of force provides a solid basis for further phases in the highest performance.

Keywords: Detente, education, effort will, power.

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667 Effect of S-Girdling on Fruit Growth and Fruit Quality of Wax Apple

Authors: Minh Tuan, Nguyen, Chung –Ruey, Yen

Abstract:

The study was performed to evaluate the effect of Sgirdling, fruit thinning plus bagging with 2,4-D application, fruit thinning plus bagging on growth and quality of wax apple fruit. Girdling was applied three week before flowering. The 2,4-D was sprayed at the small bud and petal fall stage. The effect of all treatments on fruit growth was measured weekly. The physical and biochemical quality characteristics of the fruits were recorded. The results showed that no significant effect on number of bud among treatments. S-girdling, 2,4-D application produced the lowest bud drop, fruit drop compared to untreated control. Moreover, S-girdling enhanced faster fruit growth producing the best final fruit length and diameter than the control treatment. It was also observed that Sgirdling greatly increased fruit set, fruit weight as well as total soluble solid, reduced fruit crack, and titratable acidity. In conclusion, S-girdling had a distinctive and significant effect on most of the fruit quality characteristics assessed. Application 2,4-D was also recommended as the industry norm to increase fruit set, and fruit quality in wax apple.

Keywords: Wax apple, S-girdling, 2, 4-D, fruit bagging, fruit thinning.

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666 Tin (II) Chloride a Suitable Wetting Agent for AA1200 - SiC Composites

Authors: S. O. Adeosun, E. I. Akpan, S. A. Balogun, A. S. Abdulmunim

Abstract:

SiC reinforced Aluminum samples were produced by stir casting of liquid AA1200 aluminum alloy at 600-650ºC casting temperature. 83µm SiC particles were rinsed in 10g/l, 20g/l and 30g/l molar concentration of Sncl2 through cleaning times of 0, 60, 120, and 180 minutes. Some cast samples were tested for mechanical properties and some were subjected to heat treatment before testing. The SnCl2 rinsed SiC reinforced aluminum exhibited higher yield strength, hardness, stiffness and elongation which increases with cleaning concentration and time up to 120 minutes, compared to composite with untreated SiC. However, the impact energy resistance decreases with cleaning concentration and time. The improved properties were attributed to good wettability and mechanical adhesion at the fiber-matrix interface. Quenching and annealing the composite samples further improve the tensile/yield strengths, elongation, stiffness, hardness similar to those of the as-cast samples.

Keywords: Al-SIC, Aluminum, Composites, Intermetallic, Reinforcement, Tensile Strength, Wetting.

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665 Effect of Dietary Linseed Oil Soap on Lamb Meat

Authors: E. Zsédely, A. Király, Cs. Szabó., K. Németh, O. Dóka, J. Schmidt

Abstract:

Theexperiment was carried out with 2x5 male Merino lambs raised under intensive conditions to investigate the effect of dietary calcium soap of linseed oil on the color and fatty acid composition of longissimusdorsi muscle. Control lambs fed a basal diet and the experimental lambs consumed a diet supplemented with 3% calcium soap of linseed oil. The color values (L*, a*, b* a*/b* and chroma) were not influenced by dietary treatment. The MUFA proportion reduced, SFA and PUFA content did not alter. As expected, the linolenic (C18:3 n3) and thusthe n-3 content significantly improved by linseed supplement (0.47 and 0.81; 0.78 and 1.16 in control and in experimental samples, respectively). Other n-3 and n-6 fatty acids had similar valuestocontrol samples. The n- 6/n-3 ratio was significantly narrower in the experimental group (6.31 vs. 9.38) but the P/S ratio did not differ betweenthe two groups.In conclusion calcium soap of linseed oil seems to be a suitable supplement form of n-3 fatty acids to improve the nutritive value of lamb meat.

Keywords: calcium soap, fatty acid, lamb meat, linseed

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664 Groundwater Quality Assessment around Nagalkeni Tannery Industrial Belt

Authors: D. Sivakumar

Abstract:

The groundwater quality was assessed nearby places of Nagalkeni, Chennai, Tamil Nadu, India. The selected physico-chemical parameters were pH, EC, TDS, total hardness (TH), anions like Ca, Mg, Na and K, and cations like SO4, NO3, Cl2, HCO3, and CO3, and Cr(VI). In order to suit the groundwater for drinking and irrigation purposes, compared the value of selected parameters with the value of selected parameters from BIS drinking water quality standard and irrigation water quality indices. The physico-chemical study of the groundwater systems of selected sites of nearby places of Nagalkeni showed that the groundwater is nearly acidic and mostly oxidizing in nature and hence, water is not suitable for drinking purpose directly. The results of the irrigation indices indicated that the groundwater samples in the study area found to be brackish water, results, groundwater from the study area is also not suitable for irrigation purpose directly, but the groundwater may be used after implementing some suitable treatment techniques.

Keywords: Physico-Chemical Parameters, Tannery Industry Effluent, Groundwater Quality Indices.

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663 Computational Analysis of Potential Inhibitors Selected Based On Structural Similarity for the Src SH2 Domain

Authors: W. P. Hu, J. V. Kumar, Jeffrey J. P. Tsai

Abstract:

The inhibition of SH2 domain regulated protein-protein interactions is an attractive target for developing an effective chemotherapeutic approach in the treatment of disease. Molecular simulation is a useful tool for developing new drugs and for studying molecular recognition. In this study, we searched potential drug compounds for the inhibition of SH2 domain by performing structural similarity search in PubChem Compound Database. A total of 37 compounds were screened from the database, and then we used the LibDock docking program to evaluate the inhibition effect. The best three compounds (AP22408, CID 71463546 and CID 9917321) were chosen for MD simulations after the LibDock docking. Our results show that the compound CID 9917321 can produce a more stable protein-ligand complex compared to other two currently known inhibitors of Src SH2 domain. The compound CID 9917321 may be useful for the inhibition of SH2 domain based on these computational results. Subsequently experiments are needed to verify the effect of compound CID 9917321 on the SH2 domain in the future studies.

Keywords: Nonpeptide inhibitor, Src SH2 domain, LibDock, molecular dynamics simulation.

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662 Improvement of Model for SIMMER Code for SFR Corium Relocation Studies

Authors: A. Bachrata, N. Marie, F. Bertrand, J. B. Droin

Abstract:

The in-depth understanding of severe accident propagation in Generation IV of nuclear reactors is important so that appropriate risk management can be undertaken early in their design process. This paper is focused on model improvements in the SIMMER code in order to perform studies of severe accident mitigation of Sodium Fast Reactor. During the design process of the mitigation devices dedicated to extraction of molten fuel from the core region, the molten fuel propagation from the core up to the core catcher has to be studied. In this aim, analytical as well as the complex thermohydraulic simulations with SIMMER-III code are performed. The studies presented in this paper focus on physical phenomena and associated physical models that influence the corium relocation. Firstly, the molten pool heat exchange with surrounding structures is analyzed since it influences directly the instant of rupture of the dedicated tubes favoring the corium relocation for mitigation purpose. After the corium penetration into mitigation tubes, the fuel-coolant interactions result in formation of debris bed. Analyses of debris bed fluidization as well as sinking into a fluid are presented in this paper.

Keywords: Corium, mitigation tubes, SIMMER-III, sodium fast reactor (SFR).

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661 An Evaluation of the Oxide Layers in Machining Swarfs to Improve Recycling

Authors: J. Uka, B. McKay, T. Minton, O. Adole, R. Lewis, S. J. Glanvill, L. Anguilano

Abstract:

Effective heat treatment conditions to obtain maximum aluminium swarf recycling are investigated in this work. Aluminium swarf briquettes underwent treatments at different temperatures and cooling times to investigate the improvements obtained in the recovery of aluminium metal. The main issue for the recovery of the metal from swarfs is to overcome the constraints due to the oxide layers present in high concentration in the swarfs since they have a high surface area. Briquettes supplied by Renishaw were heat treated at 650, 700, 750, 800 and 850 ℃ for 1-hour and then cooled at 2.3, 3.5 and 5 ℃/min. The resulting material was analysed using SEM EDX to observe the oxygen diffusion and aluminium coalescence at the boundary between adjacent swarfs. Preliminary results show that, swarf needs to be heat treated at a temperature of 850 ℃ and cooled down slowly at 2.3 ℃/min to have thin and discontinuous alumina layers between the adjacent swarf and consequently allowing aluminium coalescence. This has the potential to save energy and provide maximum financial profit in preparation of swarf briquettes for recycling.

Keywords: Aluminium, swarf, oxide layers, recycle, reuse.

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660 Nurse’s Role in Early Detection of Breast Cancer through Mammography and Genetic Screening and Its Impact on Patient's Outcome

Authors: Salwa Hagag Abdelaziz, Dorria Salem, Hoda Zaki, Suzan Atteya

Abstract:

Early detection of breast cancer saves many thousands of lives each year via application of mammography and genetic screening and many more lives could be saved if nurses are involved in breast care screening practices. So, the aim of the study was to identify nurse's role in early detection of breast cancer through mammography and genetic screening and its impact on patient's outcome. In order to achieve this aim, 400 women above 40 years, asymptomatic were recruited for mammography and genetic screening. In addition, 50 nurses and 6 technologists were involved in the study. A descriptive analytical design was used. Five tools were utilized: sociodemographic, mammographic examination and risk factors, women's before, during and after mammography, items relaying to technologists, and items related to nurses were also obtained. The study finding revealed that 3% of women detected for malignancy and 7.25% for fibroadenoma. Statistically significant differences were found between mammography results and age, family history, genetic screening, exposure to smoke, and using contraceptive pills. Nurses have insufficient knowledge about screening tests. Based on these findings the present study recommended involvement of nurses in breast care which is very important to in force population about screening practices.

Keywords: Early detection, Genetic Screening, Mammography.

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659 Emotion Dampening Strategy and Internalizing Problem Behavior: Affect Intensity as Control Variables

Authors: Jia-Ru Li, Chia-Jung Li, Ching-Wen Lin

Abstract:

Contrary to negative emotion regulation, coping with positive moods have received less attention in adolescent adjustment. However, some research has found that everyone is different on dealing with their positive emotions, which affects their adaptation and well-being. The purpose of the present study was to investigate the relationship between positive emotions dampening and internalizing behavior problems of adolescent in Taiwan. A survey was conducted and 208 students (12 to14 years old) completed the strengths and difficulties questionnaire (SDQ), the Affect Intensity Measure, and the positive emotions dampening scale. Analysis methods such as descriptive statistics, t-test, Pearson correlations and multiple regression were adapted. The results were as follows: Emotionality and internalizing problem behavior have significant gender differences. Compared to boys, girls have a higher score on negative emotionality and are at a higher risk for internalizing symptoms. However, there are no gender differences on positive emotion dampening. Additionally, in the circumstance that negative emotionality acted as the control variable, positive emotion dampening strategy was (positive) related to internalizing behavior problems. Given the results of this study, it is suggested that coaching deconstructive positive emotion strategies is to assist adolescents with internalizing behavior problems is encouraged.

Keywords: Emotion dampening strategies, internalizing problem behaviors, affect intensity.

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658 Asset Management for Educational Buildings in Egypt

Authors: M. Abdelhamid, I. Beshara, M. Ghoneim

Abstract:

In Egypt, the concept of Asset Management (AM) is new; however, the need for applying it has become crucial because deteriorating or losing an asset is unaffordable in a developing country like Egypt. Therefore the current study focuses on educational buildings as one of the most important assets regarding planning, building, operating and maintenance expenditures. The main objective of this study is to develop a SAMF for educational buildings in Egypt. The General Authority for Educational Buildings (GAEB) was chosen as a case study of the current research as it represents the biggest governmental organization responsible for planning, operating and maintaining schools in Egypt. To achieve the research objective, structured interviews were conducted with senior managers of GAEB using a pre designed questionnaire to explore the current practice of AM. Gab analysis technique was applied against best practices compounded from a vast literature review to identify gaps between current practices and the desired one. The previous steps mainly revealed; limited knowledge about strategic asset management, no clear goals, no training, no real risk plan and lack of data, technical and financial resources. Based on the findings, a SAMF for GAEB was introduced and Framework implementation steps and assessment techniques were explained in detail.

Keywords: Strategic Asset Management, Educational Building, Framework, Gab Analysis, Developing Country.

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657 Noise Depressed in a Micro Stepping Motor

Authors: Bo-Wun Huang, Jao-Hwa Kuang, J.-G. Tseng, Yan-De Wu

Abstract:

An investigation of noise in a micro stepping motor is considered to study in this article. Because of the trend towards higher precision and more and more small 3C (including Computer, Communication and Consumer Electronics) products, the micro stepping motor is frequently used to drive the micro system or the other 3C products. Unfortunately, noise in a micro stepped motor is too large to accept by the customs. To depress the noise of a micro stepped motor, the dynamic characteristics in this system must be studied. In this article, a Visual Basic (VB) computer program speed controlled micro stepped motor in a digital camera is investigated. Karman KD2300-2S non-contract eddy current displacement sensor, probe microphone, and HP 35670A analyzer are employed to analyze the dynamic characteristics of vibration and noise in a motor. The vibration and noise measurement of different type of bearings and different treatment of coils are compared. The rotating components, bearings, coil, etc. of the motor play the important roles in producing vibration and noise. It is found that the noise will be depressed about 3~4 dB and 6~7 dB, when substitutes the copper bearing with plastic one and coats the motor coil with paraffin wax, respectively.

Keywords: micro motor, noise, vibration

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656 Investigation of Silane Modified Ceramic Surface of Porous Mullite Ceramics

Authors: I. Markovska, F. Yovkova, G. Minov, D. Rusev, L. Lyubchev

Abstract:

The present research focus on the processing of mullite-based ceramics from oil refinery industrial wastes and byproducts of agricultural industry and on the investigating of silane modified surface of ceramics. Two waste products were used as initial material – waste aluminum oxide and waste rice husk. The burning - out additives used were waste rise husk. It is known that  the oxide ceramics surface is hydrophilic due to the presence of – OH groups in it. The nature of ceramic surface regarding permeation of water and hydrocarbons can be changed by further treatment with silanes. The samples were studied mainly by X-ray analysis, FT-IR absorbance measurements and microscopic analysis. The X-ray analyses showed the phase composition depends on the firing temperature and on the purity of the starting alumina. Two kind of silanes were used for the transformation of surface from hydrophilic to hydrophobic – trimethoxymethylsilane (TMMS) and trimethylclorsilane (TMCS).

Keywords: Porous mullite ceramics, waste materials, trimethoxymethylsilane, trimethylclorsilane.

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655 Hepatotoxicity Induced by Arsenic Trioxide in Adult Mice and Their Progeny

Authors: H. Bouaziz, N. Soudania, M. Essafia, I. Ben Amara, A. Hakim, K. Jamoussi, Km. Zeghal, N. Zeghal

Abstract:

In this investigation, we have evaluated the effects of arsenic trioxide on hepatic function in pregnant and lactating Swiss albino mice and their suckling pups. Experiments were carried out on female mice given 175 ppm As2O3 in their drinking water from the 14th day of pregnancy until day 14 after delivery. Our results showed a significant decrease in plasma levels of total protein and albumin, cholesterol and triglyceride in As2O3 treated mice and their pups. The hyperbilirubinemia and the increased plasma total alkaline phosphatase activity suggested the presence of cholestasis. Transaminase activities as well as lactate deshydrogenase activity in plasma, known as biomarkers of hepatocellular injury, were elevated indicating hepatic cells’ damage after treatment with As2O3. Exposure to arsenic led to an increase of liver thiobarbituric acid reactive substances level along with a concomitant decrease in the activities of superoxide dismutase, catalase and glutathione peroxidase and in glutathione.

Keywords: Antioxidant status, arsenic trioxide, hepatotoxicity, mice, oxidative stress.

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