Search results for: frequency harmonics
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 1802

Search results for: frequency harmonics

872 Symbolic Analysis of Large Circuits Using Discrete Wavelet Transform

Authors: Ali Al-Ataby , Fawzi Al-Naima

Abstract:

Symbolic Circuit Analysis (SCA) is a technique used to generate the symbolic expression of a network. It has become a well-established technique in circuit analysis and design. The symbolic expression of networks offers excellent way to perform frequency response analysis, sensitivity computation, stability measurements, performance optimization, and fault diagnosis. Many approaches have been proposed in the area of SCA offering different features and capabilities. Numerical Interpolation methods are very common in this context, especially by using the Fast Fourier Transform (FFT). The aim of this paper is to present a method for SCA that depends on the use of Wavelet Transform (WT) as a mathematical tool to generate the symbolic expression for large circuits with minimizing the analysis time by reducing the number of computations.

Keywords: Numerical Interpolation, Sparse Matrices, SymbolicAnalysis, Wavelet Transform.

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871 Dynamic Stall Vortex Formation of OA-209 Airfoil at Low Reynolds Number

Authors: Aung Myo Thu, Sang Eon Jeon, Yung Hwan Byun, Soo Hyung Park

Abstract:

The unsteady flow field around oscillating OA-209 airfoil at a Reynolds number of 3.5×105 were investigated. Three different reduced frequencies were tested in order to see how it affects the hysteresis loop of an airfoil. At a reduced frequency of 0.05 the deep dynamic stall phenomenon was observed. Lift overshooting was observed as a result of dynamic stall vortex (DSV) shedding. Further investigation was carried out to find out the cause of DSV formation and shedding over airfoil. Particle image velocimetry (PIV) and CFD tools were used and it was found out that dynamic stall separation (DSS), which is separated from leading edge separation (LES) and trailing edge separation (TES), triggered the dynamic stall vortex (DSV).

Keywords: Airfoil Flow, CFD, PIV, Dynamic Stall, Flow Separation.

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870 Overhead Estimation over Capacity of Mobile WiMAX

Authors: Saeed AL-Rashdy, Qing Guo

Abstract:

The IEEE802.16 standard which has emerged as Broadband Wireless Access (BWA) technology, promises to deliver high data rate over large areas to a large number of subscribers in the near future. This paper analyze the effect of overheads over capacity of downlink (DL) of orthogonal frequency division multiple access (OFDMA)–based on the IEEE802.16e mobile WiMAX system with and without overheads. The analysis focuses in particular on the impact of Adaptive Modulation and Coding (AMC) as well as deriving an algorithm to determine the maximum numbers of subscribers that each specific WiMAX sector may support. An analytical study of the WiMAX propagation channel by using Cost- 231 Hata Model is presented. Numerical results and discussion estimated by using Matlab to simulate the algorithm for different multi-users parameters.

Keywords: BWA, mobile WiMAX, capacity, AMC , overheads.

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869 Fuzzy PID based PSS Design Using Genetic Algorithm

Authors: Ermanu A. Hakim, Adi Soeprijanto, Mauridhi H.P

Abstract:

This paper presents PSS (Power system stabilizer) design based on optimal fuzzy PID (OFPID). OFPID based PSS design is considered for single-machine power systems. The main motivation for this design is to stabilize or to control low-frequency oscillation on power systems. Firstly, describing the linear PID control then to combine this PID control with fuzzy logic control mechanism. Finally, Fuzzy PID parameters (Kp. Kd, KI, Kupd, Kui) are tuned by Genetic Algorthm (GA) to reach optimal global stability. The effectiveness of the proposed PSS in increasing the damping of system electromechanical oscillation is demonstrated in a one-machine-infinite-bus system

Keywords: Fuzzy PID, Genetic Algorithm, power system stabilizer.

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868 Generating Frequent Patterns through Intersection between Transactions

Authors: M. Jamali, F. Taghiyareh

Abstract:

The problem of frequent itemset mining is considered in this paper. One new technique proposed to generate frequent patterns in large databases without time-consuming candidate generation. This technique is based on focusing on transaction instead of concentrating on itemset. This algorithm based on take intersection between one transaction and others transaction and the maximum shared items between transactions computed instead of creating itemset and computing their frequency. With applying real life transactions and some consumption is taken from real life data, the significant efficiency acquire from databases in generation association rules mining.

Keywords: Association rules, data mining, frequent patterns, shared itemset.

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867 Dissipation of Higher Mode using Numerical Integration Algorithm in Dynamic Analysis

Authors: Jin Sup Kim, Woo Young Jung, Minho Kwon

Abstract:

In general dynamic analyses, lower mode response is of interest, however the higher modes of spatially discretized equations generally do not represent the real behavior and not affects to global response much. Some implicit algorithms, therefore, are introduced to filter out the high-frequency modes using intended numerical error. The objective of this study is to introduce the P-method and PC α-method to compare that with dissipation method and Newmark method through the stability analysis and numerical example. PC α-method gives more accuracy than other methods because it based on the α-method inherits the superior properties of the implicit α-method. In finite element analysis, the PC α-method is more useful than other methods because it is the explicit scheme and it achieves the second order accuracy and numerical damping simultaneously.

Keywords: Dynamic, α-Method, P-Method, PC α-Method, Newmark method.

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866 Reduction of Peak Input Currents during Charge Pump Boosting in Monolithically Integrated High-Voltage Generators

Authors: Jan Doutreloigne

Abstract:

This paper describes two methods for the reduction of the peak input current during the boosting of Dickson charge pumps. Both methods are implemented in the fully integrated Dickson charge pumps of a high-voltage display driver chip for smart-card applications. Experimental results reveal good correspondence with Spice simulations and show a reduction of the peak input current by a factor of 6 during boosting.

Keywords: Bi-stable display driver, Dickson charge pump, highvoltage generator, peak current reduction, sub-pump boosting, variable frequency boosting.

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865 Reflection Performance of Truncated Pyramidal and Truncated Wedge Microwave Absorber Using Sugarcane Bagasse (SCB)

Authors: Liyana Zahid, Mohd Fareq Abd Malek, Ee Meng Cheng, Wei Wen Liu, Yeng Seng Lee, Muhammad Nadeem Iqbal, Fwen Hoon Wee, Farrah Salwani Abdullah

Abstract:

One of the parameters that affect the performance of microwave absorbers is the shape of the absorbers. This paper shows the performance (reflection loss) of truncated pyramidal and truncated wedge microwave absorbers in the range frequency between 8.2 to 12.4 GHz (X-Band) in simulation. The material used is sugarcane bagasse (SCB) which is one of the new materials that used to fabricate the microwave absorber. The complex permittivity was measured using Agilent dielectric probe technique. The designs were simulated using CST Microwave Studio Software. The reflection losses between these two shapes were compared.

Keywords: Microwave Absorber, Reflection Loss, Sugarcane Bagasse (SCB), X- Band.

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864 A Real-Time Signal Processing Technique for MIDI Generation

Authors: Farshad Arvin, Shyamala Doraisamy

Abstract:

This paper presents a new hardware interface using a microcontroller which processes audio music signals to standard MIDI data. A technique for processing music signals by extracting note parameters from music signals is described. An algorithm to convert the voice samples for real-time processing without complex calculations is proposed. A high frequency microcontroller as the main processor is deployed to execute the outlined algorithm. The MIDI data generated is transmitted using the EIA-232 protocol. The analyses of data generated show the feasibility of using microcontrollers for real-time MIDI generation hardware interface.

Keywords: Signal processing, MIDI, Microcontroller, EIA-232.

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863 Evaluation Using a Bidirectional Microphone as a Pressure Pulse Wave Meter

Authors: S. Fujiwara, T. Kaburagi, K. Kobayashi, K. Watanabe, Y. Kurihara

Abstract:

This paper describes a novel sensor device, a pressure pulse wave meter, which uses a bidirectional condenser microphone. The microphone work as a microphone as well as a sensor with high gain over a wide frequency range; they are also highly reliable and economic. Currently aging is becoming a serious social issue in Japan causing increased medical expenses in the country. Hence, it is important for elderly citizens to check health condition at home, and to care the health conditions through daily monitoring. Given this circumstances, we developed a novel pressure pulse wave meter based on a bidirectional condenser microphone: this device is used as a measuring instrument of health conditions.

Keywords: Bidirectional microphone, pressure pulse wave meter, health condition.

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862 Signal Transmission Analysis of Differential Pairs Using Semicircle-Shaped Via Structure

Authors: Moonjung Kim, Chang-Ho Hyun, Won-Ho Kim

Abstract:

In this paper, the signal transmission analysis of the semicircle-shaped via structure for the differential pairs is presented in the frequency range up to 10 GHz. In order to improve the signal transmission properties in the differential pairs, single via is separated centrally into two semicircle-shaped sections, which are interconnected with the traces of differential pairs respectively. This via structure make possible to route differential pairs using only one via. In addition, it can improve impedance discontinuity around its region and then enhance the signal transmission properties in the differential pairs. The electrical analysis such as S-parameter calculation and eye diagram simulation has been performed to investigate the improvement of the signal transmission property in the differential pairs with new via structure.

Keywords: Differential pairs, signal transmission property, via, S-parameter.

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861 Microwave Absorption Properties of Low Density Polyethelene-Cobalt Ferrite Nanocomposite

Authors: R. Fazaeli, R. Eslami-Farsani, H. Targhagh

Abstract:

Low density polyethylene (LDPE) nanocomposites with 3, 5 and 7 wt. % cobalt ferrite (CoFe2O4) nanopowder fabricated with extrusion mixing and followed up by hot press to reach compact samples. The transmission/reflection measurements were carried out with a network analyzer in the frequency range of 8-12 GHz. By increasing the percent of CoFe2O4 nanopowder, reflection loss (S11) increases, while transferring loss (S21) decreases. Reflectivity (R) calculations made using S11 and S21. Increase in percent of CoFe2O4 nanopowder up to 7 wt. % in composite leaded to higher reflectivity amount, and revealed that increasing the percent of CoFe2O4 nanopowder up to 7 wt. % leads to further microwave absorption in 8-12 GHz range.

Keywords: Nanocomposite, Cobalt Ferrite, Low Density Polyethylene, Microwave Absorption.

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860 Human Immunodeficiency Virus Infection and Cardiac Autonomic Neuropathy

Authors: Sharan Badiger, Prema T. Akkasaligar, Deepak Kadeli

Abstract:

Human Immunodeficiency Virus is known to affect almost all organ systems in the body. In addition to central nervous system it also affects the autonomic nervous system. Autonomic nervous dysfunction has been known to severely affect the quality of life in human immunodeficiency virus positive patients. It is known to have caused fatal consequences in late stages of the disease in patients who go in for invasive diagnostic or therapeutic procedures. The aim of this review is to determine the incidence, clinical significance and frequency of cardiac autonomic neuropathy in patients human immunodeficiency virus infection.

Keywords: Autonomic nervous system, autonomic nervous dysfunction, cardiac autonomic dysfunction, human immunodeficiency virus.

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859 On-Chip Aging Sensor Circuit Based on Phase Locked Loop Circuit

Authors: Ararat Khachatryan, Davit Mirzoyan

Abstract:

In sub micrometer technology, the aging phenomenon starts to have a significant impact on the reliability of integrated circuits by bringing performance degradation. For that reason, it is important to have a capability to evaluate the aging effects accurately. This paper presents an accurate aging measurement approach based on phase-locked loop (PLL) and voltage-controlled oscillator (VCO) circuit. The architecture is rejecting the circuit self-aging effect from the characteristics of PLL, which is generating the frequency without any aging phenomena affects. The aging monitor is implemented in low power 32 nm CMOS technology, and occupies a pretty small area. Aging simulation results show that the proposed aging measurement circuit improves accuracy by about 2.8% at high temperature and 19.6% at high voltage.

Keywords: Nanoscale, aging, effect, NBTI, HCI.

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858 Axisymmetric Vibration of Pyrocomposite Hollow Cylinder

Authors: V. K. Nelson, S. Karthikeyan

Abstract:

Axisymmetric vibration of an infinite Pyrocomposite circular hollow cylinder made of inner and outer pyroelectric layer of 6mm-class bonded together by a Linear Elastic Material with Voids (LEMV) layer is studied. The exact frequency equation is obtained for the traction free surfaces with continuity condition at the interfaces. Numerical results in the form of data and dispersion curves for the first and second mode of the axisymmetric vibration of the cylinder BaTio3 / Adhesive / BaTio3 by taking the Adhesive layer as an existing Carbon Fibre Reinforced Polymer (CFRP) are compared with a hypothetical LEMV layer with and without voids and as well with a pyroelectric hollow cylinder. The damping is analyzed through the imaginary parts of the complex frequencies.

Keywords: Axisymmetric vibration, CFRP, hollow cylinders, LEMV, pyrocomposite

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857 Thermal Performance of a Pair of Synthetic Jets Equipped in Microchannel

Authors: J. Mohammadpour, G. E. Lau, S. Cheng, A. Lee

Abstract:

Numerical study was conducted using two synthetic jet actuators attached underneath a micro-channel. By fixing the oscillating frequency and diaphragm amplitude, the effects on the heat transfer within the micro-channel were investigated with two synthetic jets being in-phase and 180° out-of-phase at different orifice spacing. There was a significant benefit identified with two jets being 180° out-of-phase with each other at the orifice spacing of 2 mm. By having this configuration, there was a distinct pattern of vortex forming which disrupts the main channel flow as well as promoting thermal mixing at high velocity within the channel. Therefore, this configuration achieved higher cooling performance compared to the other cases studied in terms of the reduction in the maximum temperature and cooling uniformity in the silicon wafer.

Keywords: Synthetic jets, microchannel, electronic cooling, computational fluid dynamics.

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856 Vibration Damping of High-Chromium Ferromagnetic Steel

Authors: Satish BM, Girish BM , Mahesh K

Abstract:

The aim of the present work is to study the effect of annealing on the vibration damping capacity of high-chromium (16%) ferromagnetic steel. The alloys were prepared from raw materials of 99.9% purity melted in a high frequency induction furnace under high vacuum. The samples were heat-treated in vacuum at various temperatures (800 to 1200ºC) for 1 hour followed by slow cooling (120ºC/h). The inverted torsional pendulum method was used to evaluate the vibration damping capacity. The results indicated that the vibration damping capacity of the alloys is influenced by annealing and there exists a critical annealing temperature after 1000ºC. The damping capacity increases quickly below the critical temperature since the magnetic domains move more easily.

Keywords: Vibration, Damping, Ferromagnetic, Steel.

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855 Efficient Time Synchronization in Wireless Sensor Networks

Authors: Shehzad Ashraf Ch., Aftab Ahmed Khan, Zahid Mehmood, Muhammad Ahsan Habib, Qasim Mehmood

Abstract:

Energy efficiency is the key requirement in wireless sensor network as sensors are small, cheap and are deployed in very large number in a large geographical area, so there is no question of replacing the batteries of the sensors once deployed. Different ways can be used for efficient energy transmission including Multi-Hop algorithms, collaborative communication, cooperativecommunication, Beam- forming, routing algorithm, phase, frequency and time synchronization. The paper reviews the need for time synchronization and proposed a BFS based synchronization algorithm to achieve energy efficiency. The efficiency of our protocol has been tested and verified by simulation

Keywords: time synchronization, sensor networks, energy efficiency, breadth first search

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854 The Minimum PAPR Code for OFDM Systems

Authors: Inderjeet Kaur, M. Kulkarni, Daya Gupta, Kamal Thakur, Janki Arora

Abstract:

In this paper, a block code to minimize the peak-toaverage power ratio (PAPR) of orthogonal frequency division multiplexing (OFDM) signals is proposed. It is shown that cyclic shift and codeword inversion cause not change to peak envelope power. The encoding rule for the proposed code comprises of searching for a seed codeword, shifting the register elements, and determining codeword inversion, eliminating the look-up table for one-to-one correspondence between the source and the coded data. Simulation results show that OFDM systems with the proposed code always have the minimum PAPR.

Keywords: Wireless communications, OFDM, peak-to averagepower ratio, peak envelope power, block codes.

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853 A Weighted Least Square Algorithm for Low-Delay FIR Filters with Piecewise Variable Stopbands

Authors: Yasunori Sugita, Toshinori Yoshikawa, Naoyuki Aikawa

Abstract:

Variable digital filters are useful for various signal processing and communication applications where the frequency characteristics, such as fractional delays and cutoff frequencies, can be varied. In this paper, we propose a design method of variable FIR digital filters with an approximate linear phase characteristic in the passband. The proposed variable FIR filters have some large attenuation in stopband and their large attenuation can be varied by spectrum parameters. In the proposed design method, a quasi-equiripple characteristic can be obtained by using an iterative weighted least square method. The usefulness of the proposed design method is verified through some examples.

Keywords: Weighted Least Squares Approximation, Variable FIR Filters, Low-Delay, Quasi-Equiripple

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852 Optimization of the Structures of the Electric Feeder Systems of the Oil Pumping Plants in Algeria

Authors: M. Bouguerra, F. Laaouad, I. Habi, R. Azaizia

Abstract:

In Algeria, now, the oil pumping plants are fed with electric power by independent local sources. This type of feeding has many advantages (little climatic influence, independent operation). However it requires a qualified maintenance staff, a rather high frequency of maintenance and repair and additional fuel costs. Taking into account the increasing development of the national electric supply network (Sonelgaz), a real possibility of transfer of the local sources towards centralized sources appears.These latter cannot only be more economic but more reliable than the independent local sources as well. In order to carry out this transfer, it is necessary to work out an optimal strategy to rebuilding these networks taking in account the economic parameters and the indices of reliability.

Keywords: Optimization, reliability, electric network.

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851 The Comparisons of Average Outgoing Quality Limit between the MCSP-2-C and MCSP-C

Authors: P. Guayjarernpanishkand, T. Mayureesawan

Abstract:

This paper presents a comparison of average outgoing quality limit of the MCSP-2-C plan with MCSP-C when MCSP-2-C has been developed from MCSP-C. The parameters used in MCSP-2- C are: i (the clearance number), c (the acceptance number), m (the number of conforming units to be found before allowing c nonconforming units in the sampling inspection), f1 and f2 (the sampling frequency at level 1 and 2, respectively). The average outgoing quality limit (AOQL) values from two plans were compared and we found that for all sets of i, r, and c values, MCSP-2-C gives higher values than MCSP-C. For all sets of i, r, and c values, the average outgoing quality values of MCSP-C and MCSP-2-C are similar when p is low or high but is difference when p is moderate.

Keywords: average outgoing quality, average outgoing quality limit, continuous sampling plan.

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850 Exact Analysis of Resonance Frequencies of Simply Supported Cylindrical Shells

Authors: A. Farshidianfar, P. Oliazadeh, M. H. Farshidianfar

Abstract:

In order to study the free vibration of simply supported circular cylindrical shells; an analytical procedure is developed and discussed in detail. To identify its’ validity, the exact technique was applied to four different shell theories 1) Soedel, 2) Flugge, 3) Morley-Koiter, and 4) Donnell. The exact procedure was compared favorably with experimental results and those obtained using the numerical finite element method. A literature review reveals that beam functions are used extensively as an approximation for simply supported boundary conditions. The effects of this approximate method were also investigated on the natural frequencies by comparing results with those of the exact analysis.

Keywords: Circular Cylindrical Shell, Free Vibration, Natural Frequency.

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849 Optimum Stratification of a Skewed Population

Authors: D.K. Rao, M.G.M. Khan, K.G. Reddy

Abstract:

The focus of this paper is to develop a technique of solving a combined problem of determining Optimum Strata Boundaries(OSB) and Optimum Sample Size (OSS) of each stratum, when the population understudy isskewed and the study variable has a Pareto frequency distribution. The problem of determining the OSB isformulated as a Mathematical Programming Problem (MPP) which is then solved by dynamic programming technique. A numerical example is presented to illustrate the computational details of the proposed method. The proposed technique is useful to obtain OSB and OSS for a Pareto type skewed population, which minimizes the variance of the estimate of population mean.

Keywords: Stratified sampling, Optimum strata boundaries, Optimum sample size, Pareto distribution, Mathematical programming problem, Dynamic programming technique.

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848 Biosignal Measurement System Based On Ultra-Wide Band Human Body Communication

Authors: Jonghoon Kim, Gilwon Yoon

Abstract:

A wrist-band type biosignal measurement system and its data transfer through human body communication (HBC) were investigated. An HBC method based on pulses of ultra-wide band instead of using frequency or amplitude modulations was studied and implemented since the system became very compact and it was more suited for personal or mobile health monitoring. Our system measured photo-plethysmogram (PPG) and measured PPG signals were transmitted through a finger to a monitoring PC system. The device was compact and low-power consuming. HBC communication has very strongsecurity measures since it does not use wireless network.Furthermore, biosignal monitoring system becomes handy because it does not need to have wire connections.

Keywords: Biosignal, human body communication, mobile health, PPG, ultrawide band.

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847 Wideband Tunable RF Filters for Channel Selection in Crowded Spectral Bands

Authors: Sanghoon Park, Ki-Jin Kim, Kwang-Ho Ahn, Hyeon-Woo Lee

Abstract:

It is very effective way to utilize a very wide tunable filter in co-existing multi-standards wireless communications environment. Especially, as the long term evolution (LTE) communication era has come, the multi-band coverage is one of the important features required for the RF components. In this paper, we present the frequency conversion technique, and so generate two types of RF filters which are specially designed for the superb tunable ability to support multiple wireless communication standards. With the help of a complex mixing structure, the inherent image signal is suppressed. The RF band-pass filter (BPF) and notch filter achieve 1.8dB and 1.6dB insertion losses and 18 dB and 17 dB attenuations, respectively. The quality factor show greater than 30.

Keywords: RF filters, interference, wideband, tunable, channel selection, complex mixing, balanced mixer.

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846 High Directivity and Gain Enhancement for Small Planar Dipole Antenna at 11 GHz Using Symmetrical Pyramidal Block Based On Epsilon Negative Medium

Authors: V. Kesornpatumanun, P. Boonek, W. Silabut, N. Homsup, W. Kuhirun

Abstract:

This paper increases directivity and gain of Small Planar Dipole Antenna (SPDA) by using Symmetrical Pyramidal Block (SPB) which operates in X band at 11 GHz. The SPB consists four sides; each of which is metamaterial with Epsilon Negative Medium (ENG) and Epsilon Near-Zero (ENZ). The results simulated using the High Frequency Structure Simulator (HFSS) show that the SPB is capable of enhancing directivity and gain for the SPDA with maximum gain of 2.46 dB. The reflection coefficient is -13.7037 dB with narrow beam width.

Keywords: Small Planar Dipole Antenna, Symmetrical Pyramidal Block, metamaterials, Epsilon Near-Zero, Epsilon Negative Medium.

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845 A Transform-Free HOC Scheme for Incompressible Viscous Flow past a Rotationally Oscillating Circular Cylinder

Authors: Rajendra K. Ray, H. V. R. Mittal

Abstract:

A numerical study is made of laminar, unsteady flow behind a rotationally oscillating circular cylinder using a recently developed higher order compact (HOC) scheme. The stream function vorticity formulation of Navier-Stokes (N-S) equations in cylindrical polar coordinates are considered as the governing equations. The temporal behaviour of vortex formation and relevant streamline patterns of the flow are scrutinized over broad ranges of two externally specified parameters namely dimensionless forced oscillating frequency Sf and dimensionless peak rotation rate αm for the Reynolds-s number Re = 200. Excellent agreements are found both qualitatively and quantitatively with the existing experimental and standard numerical results.

Keywords: HOC, Navier-Stokes, non-uniform polar grids, rotationally oscillating cylinder.

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844 Performance Analysis of a Hybrid DF-AF Hybrid RF/FSO System under Gamma Gamma Atmospheric Turbulence Channel Using MPPM Modulation

Authors: Hechmi Saidi, Noureddine Hamdi

Abstract:

The performance of hybrid amplify and forward - decode and forward (AF-DF) hybrid radio frequency/free space optical (RF/FSO) communication system, that adopts M-ary pulse position modulation (MPPM) techniques, is analyzed. Both exact and approximate symbol-error rates (SERs) are derived. The random variations of the received optical irradiance, produced by the atmospheric turbulence, is modeled by the gamma-gamma (GG) statistical distribution. A closed-form expression for the probability density function (PDF) is derived for the whole above system is obtained. Thanks to the use of hybrid AF-DF hybrid RF/FSO configuration and MPPM, the effects of atmospheric turbulence is mitigated; hence the capacity of combating atmospheric turbulence and the transmissitted signal quality are improved.

Keywords: FSO, RF, hybrid, AF, DF, SER, SNR, GG channel.

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843 Determination of Cyclic Citrullinated Peptide Antibodies on Quartz Crystal Microbalance Based Nanosensors

Authors: Y. Saylan, F. Yılmaz, A. Denizli

Abstract:

In this study, we have focused our attention on combining of molecular imprinting into nanofilms and QCM nanosensor approaches and producing QCM nanosensor for anti- CCP, chosen as model protein, using anti-CCP imprinted nanofilms. The nonimprinted nanosensor was also prepared to evaluate the selectivity of the imprinted nanosensor. Anti-CCP imprinted QCM nanosensor was tested for real time detection of anti-CCP from aqueous solution. The kinetic and affinity studies were determined by using anti-CCP solutions with different concentrations. The responses related with mass shifts (%m) and frequency shifts (%f) were used to evaluate adsorption properties. To show the selectivity of the anti-CCP imprinted QCM nanosensor, competitive adsorption of anti-CCP and IgM was investigated. The results indicate that anti- CCP imprinted QCM nanosensor has higher adsorption capabilities for anti-CCP than for IgM, due to selective cavities in the polymer structure.

Keywords: Anti-CCP, molecular imprinting, QCM nanosensor, rheumatoid arthritis.

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