Search results for: Mohamed M. M.Ahmed
2296 Large Time Asymptotic Behavior to Solutions of a Forced Burgers Equation
Authors: Satyanarayana Engu, Ahmed Mohd, V. Murugan
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We study the large time asymptotics of solutions to the Cauchy problem for a forced Burgers equation (FBE) with the initial data, which is continuous and summable on R. For which, we first derive explicit solutions of FBE assuming a different class of initial data in terms of Hermite polynomials. Later, by violating this assumption we prove the existence of a solution to the considered Cauchy problem. Finally, we give an asymptotic approximate solution and establish that the error will be of order O(t^(-1/2)) with respect to L^p -norm, where 1≤p≤∞, for large time.Keywords: Burgers equation, Cole-Hopf transformation, Hermite polynomials, large time asymptotics
Procedia PDF Downloads 3242295 Contribution of Algerians Local Materials on the Compressive Strengths of Concrete: Experimental and Numerical Study
Authors: Mohamed Lyes Kamel Khouadjia, Bouzidi Mezghiche
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The evolution in the civil engineering and carried out more consumption of aggregates and particularly the sand. Due to the depletion of natural reserves of sand, it is necessary to focus on the use of local materials such as crushed sand, river sand and dune sand, mineral additions. The aim of this work is to improve the state of knowledge on the compressive strengths of crushed sands with several mixtures (dune sand, river sand, pozzolan, and slag). The obtained results were compared with numerical results obtained with the software Béton Lab Pro 3.Keywords: crushed sand, river sand, dune sand, pouzzolan, slag, compressive strengths, Béton Lab Pro 3
Procedia PDF Downloads 3082294 Bayesian Reliability of Weibull Regression with Type-I Censored Data
Authors: Al Omari Moahmmed Ahmed
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In the Bayesian, we developed an approach by using non-informative prior with covariate and obtained by using Gauss quadrature method to estimate the parameters of the covariate and reliability function of the Weibull regression distribution with Type-I censored data. The maximum likelihood seen that the estimators obtained are not available in closed forms, although they can be solved it by using Newton-Raphson methods. The comparison criteria are the MSE and the performance of these estimates are assessed using simulation considering various sample size, several specific values of shape parameter. The results show that Bayesian with non-informative prior is better than Maximum Likelihood Estimator.Keywords: non-informative prior, Bayesian method, type-I censoring, Gauss quardature
Procedia PDF Downloads 4922293 High Voltage Magnetic Pulse Generation Using Capacitor Discharge Technique
Authors: Mohamed Adel Abdallah
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A high voltage magnetic pulse is designed by applying an electrical pulse to the coil. Capacitor banks are developed to generate a pulse current. Switching circuit consisting of DPDT switches, thyristor, and triggering circuit is built and tested. The coil current is measured using a Hall-effect current sensor. The magnetic pulse created is measured and tabulated in the graph. Simulation using FEMM is done to compare the results obtained between experiment and simulation. This technology can be applied to area such as medical equipment, measuring instrument, and military equipment.Keywords: high voltage, magnetic pulse, capacitor discharge, coil
Procedia PDF Downloads 6722292 Use of Hierarchical Temporal Memory Algorithm in Heart Attack Detection
Authors: Tesnim Charrad, Kaouther Nouira, Ahmed Ferchichi
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In order to reduce the number of deaths due to heart problems, we propose the use of Hierarchical Temporal Memory Algorithm (HTM) which is a real time anomaly detection algorithm. HTM is a cortical learning algorithm based on neocortex used for anomaly detection. In other words, it is based on a conceptual theory of how the human brain can work. It is powerful in predicting unusual patterns, anomaly detection and classification. In this paper, HTM have been implemented and tested on ECG datasets in order to detect cardiac anomalies. Experiments showed good performance in terms of specificity, sensitivity and execution time.Keywords: cardiac anomalies, ECG, HTM, real time anomaly detection
Procedia PDF Downloads 2112291 Phytoremediation of Zn-Contaminated Soils by Malva Sylvestris
Authors: Abdelouahab Diafat, Meribai Abdelmalek, Ahmed Bahloul
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phytoremediation is the use of plants to remove or degrade organic or inorganic contaminants from soil and water this work aims to study the potential effect of malva sylvestris for the phytoremediation of soils contaminated by Zn. plants were grown in pots containing soil artificially contaminated with Zn at concentrations of 100, 200, and 300 mg/kg. the results obtained show that the Zn concentrations used have a negative effect on the growth of this plant the search for the metal carried out by the technique of atomic absorption spectrometry shows that this plant accumulates a small quantity of this metal. it can be concluded that the malva sylvestris plant tolerates Zn contaminated soils but it is not considered as a zinc hyperaccumulator plantKeywords: phytoremidiation, Zn-contaminated soils, Malva Sylvestris, phytoextraction
Procedia PDF Downloads 732290 SVM-DTC Using for PMSM Speed Tracking Control
Authors: Kendouci Khedidja, Mazari Benyounes, Benhadria Mohamed Rachid, Dadi Rachida
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In recent years, direct torque control (DTC) has become an alternative to the well-known vector control especially for permanent magnet synchronous motor (PMSM). However, it presents a problem of field linkage and torque ripple. In order to solve this problem, the conventional DTC is combined with space vector pulse width modulation (SVPWM). This control theory has achieved great success in the control of PMSM. That has become a hotspot for resolving. The main objective of this paper gives us an introduction of the DTC and SVPWM-DTC control theory of PMSM which has been simulating on each part of the system via Matlab/Simulink based on the mathematical modeling. Moreover, the outcome of the simulation proved that the improved SVPWM- DTC of PMSM has a good dynamic and static performance.Keywords: PMSM, DTC, SVM, speed control
Procedia PDF Downloads 3782289 Experimental Investigations of a Modified Taylor-Couette Flow
Authors: Ahmed Esmael, Ali El Shrif
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In this study the instability problem of a modified Taylor-Couette flow between two vertical coaxial cylinders of radius R1, R2 is considered. The modification is based on the wavy shape of the inner cylinder surface, where inner cylinders with different surface amplitude and wavelength are used. The study aims to discover the effect of the inner surface geometry on the instability phenomenon that undergoes Taylor-Couette flow. The study reveals that the transition processes depends strongly on the amplitude and wavelength of the inner cylinder surface and resulting in flow instabilities that are strongly different from that encountered in the case of the classical Taylor-Couette flow.Keywords: hydrodynamic instability, Modified Taylor-Couette Flow, turbulence, Taylor vortices
Procedia PDF Downloads 4262288 Application of Production Planning to Improve Operation in Local Factory
Authors: Bashayer Al-Enezi, Budoor Al-Sabti, Eman Al-Durai, Fatmah Kalban, Meshael Ahmed
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Production planning and control principles are concerned with planning, controlling and balancing all aspects of manufacturing including raw materials, finished goods, production schedules, and equipment requirements. Hence, an effective production planning and control system is very critical to the success of any factory. This project will focus on the application of production planning and control principles on “The National Canned Food Production and Trading Company (NCFP)” factory to find problems or areas for improvement.Keywords: production planning, operations improvement, inventory management, National Canned Food Production and Trading Company (NCFP)
Procedia PDF Downloads 4922287 Prey-Predator Eco-Epidemiological Model with Nonlinear Transmission Disease
Authors: Qamar J. A. Khan, Fatma Ahmed Al Kharousi
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A prey-predator eco-epidemiological model is studied where transmission of the disease between infected and uninfected prey is nonlinear. The interaction of the predator with infected and uninfected prey species depend on their numerical superiority. Harvesting of both uninfected and infected prey is considered. Stability analysis is carried out for equilibrium values. Using the parameter µ, the death rate of infected prey as a bifurcation parameter it is shown that Hopf bifurcation could occur. The theoretical results are compared with numerical results for different set of parameters.Keywords: bifurcation, optimal harvesting, predator, prey, stability
Procedia PDF Downloads 2932286 Effect of Span 60, Labrasol, and Cholesterol on Labisia pumila Loaded Niosomes Quality
Authors: H. Binti Ya’akob, C. Siew Chin, A. Abd Aziz, I. Ware, M. Fauzi Abd Jalil, N. Rashidah Ahmed, R. Sabtu
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Labisia pumila (LP) plant extract has the potential to be applied in cosmeceutical products due to its anti-photoaging properties. The main purpose of this study was to improve transdermal delivery of LP by encapsulating LP in niosomes. Niosomes loaded LPs were prepared by coacervation phase separation method using non-ionic surfactant (Span 60), labrasol, and cholesterol. The optimum formula obtained were Span 60, labrasol and cholesterol at the mole ratio of 6:1:4. At the optimum formulation, the niosome obtained significantly improved the quality of transdermal penetration of LP compared to free LP.Keywords: Labisia pumila, niosomes, transdermal, quality
Procedia PDF Downloads 3072285 Geometallurgy of Niobium Deposits: An Integrated Multi-Disciplined Approach
Authors: Mohamed Nasraoui
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Spatial ore distribution, ore heterogeneity and their links with geological processes involved in Niobium concentration are all factors for consideration when bridging field observations to extraction scheme. Indeed, mineralogy changes of Nb-hosting phases, their textural relationships with hydrothermal or secondary minerals, play a key control over mineral processing. This study based both on filed work and ore characterization presents data from several Nb-deposits related to carbonatite complexes. The results obtained by a wide range of analytical techniques, including, XRD, XRF, ICP-MS, SEM, Microprobe, Spectro-CL, FTIR-DTA and Mössbauer spectroscopy, demonstrate how geometallurgical assessment, at all stage of mine development, can greatly assist in the design of a suitable extraction flowsheet and data reconciliation.Keywords: carbonatites, Nb-geometallurgy, Nb-mineralogy, mineral processing.
Procedia PDF Downloads 1542284 Physicochemical Characterization of Mercerized Cellulose-Supported Nickel-Oxide
Authors: Sherif M. A. S. Keshk, Hisham S. M. Abd-Rabboh, Mohamed S. Hamdy, Ibrahim H. A. Badr
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Microwave radiation was applied to synthesize nanoparticles of nickel oxide supported on pretreated cellulose with metal acetate in the presence of NaOH. Optimization, in terms of irradiation time and metal concentration, was investigated. FT-IR spectrum of cellulose/NiO spectrum shows a band at 445 cm^-1 that is related to the Ni–O stretching vibration of NiO6 octahedral in the cubic NiO structure. cellulose/NiO showed similar XRD pattern of cellulose I and exhibited sharpened reflection peak at 2q = 29.8°, corresponding to (111) plane of NiO, with two weak broad peaks at 48.5°, and 49.2°, representing (222) planes of NiO. XPS spectrum of mercerized cellulose/NiO composite showed did not show any peaks corresponding to Na ion.Keywords: cellulose, mercerized cellulose, cellulose/zinc and nickeloxides composite, FTIR, XRD, XPS, SEM, Raman spectrum
Procedia PDF Downloads 4342283 Variations of Testing Concrete Mechanical Properties by European Standard and American Code
Authors: Ahmed M. Seyam, Rita Nemes, Salem Georges Nehme
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Europe and the United States have a worldwide significance in the field of concrete control and construction; according to that, a lot of countries adopted their standards and regulations in the concrete field, as proof of the Europe and US strong standards and due to lack of own regulations. The main controlled property of concrete are the compressive strength, flexure tensile strength, and modulus of elasticity as it relates both to its bearing capacity and to the durability of the elements built with it, so in this paper, ASTM standard and EN standards method of testing those properties were put under the microscope to compare the variations between them.Keywords: concrete, ASTM, EU standards, compressive strength, flexural strength, modulus of elasticity
Procedia PDF Downloads 842282 ACOPIN: An ACO Algorithm with TSP Approach for Clustering Proteins in Protein Interaction Networks
Authors: Jamaludin Sallim, Rozlina Mohamed, Roslina Abdul Hamid
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In this paper, we proposed an Ant Colony Optimization (ACO) algorithm together with Traveling Salesman Problem (TSP) approach to investigate the clustering problem in Protein Interaction Networks (PIN). We named this combination as ACOPIN. The purpose of this work is two-fold. First, to test the efficacy of ACO in clustering PIN and second, to propose the simple generalization of the ACO algorithm that might allow its application in clustering proteins in PIN. We split this paper to three main sections. First, we describe the PIN and clustering proteins in PIN. Second, we discuss the steps involved in each phase of ACO algorithm. Finally, we present some results of the investigation with the clustering patterns.Keywords: ant colony optimization algorithm, searching algorithm, protein functional module, protein interaction network
Procedia PDF Downloads 6012281 An Excel-Based Educational Platform for Design Analyses of Pump-Pipe Systems
Authors: Mohamed M. El-Awad
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This paper describes an educational platform for design analyses of pump-pipe systems by using Microsoft Excel, its Solver add-in, and the associated VBA programming language. The paper demonstrates the capabilities of the Excel-based platform that suits the iterative nature of the design process better than the use of design charts and data tables. While VBA is used for the development of a user-defined function for determining the standard pipe diameter, Solver is used for optimising the pipe diameter of the pipeline and for determining the operating point of the selected pump.Keywords: design analyses, pump-pipe systems, Excel, solver, VBA
Procedia PDF Downloads 1572280 Chemical Variability in the Essential Oils from the Leaves and Buds of Syzygium Species
Authors: Rabia Waseem, Low Kah Hin, Najihah Mohamed Hashim
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The variability in the chemical components of the Syzygium species essential oils has been evaluated. The leaves of Syzygium species have been collected from Perak, Malaysia. The essential oils extracted by using the conventional Hydro-distillation extraction procedure and analyzed by using Gas chromatography System attached with Mass Spectrometry (GCMS). Twenty-seven constituents were found in Syzygium species in which the major constituents include: α-Pinene (3.94%), α-Thujene (2.16%), α-Terpineol (2.95%), g-Elemene (2.89%) and D-Limonene (14.59%). The aim of this study was the comparison between the evaluated data and existing literature to fortify the major variability through statistical analysis.Keywords: chemotaxonomy, cluster analysis, essential oil, medicinal plants, statistical analysis
Procedia PDF Downloads 3042279 Harmony Search-Based K-Coverage Enhancement in Wireless Sensor Networks
Authors: Shaimaa M. Mohamed, Haitham S. Hamza, Imane A. Saroit
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Many wireless sensor network applications require K-coverage of the monitored area. In this paper, we propose a scalable harmony search based algorithm in terms of execution time, K-Coverage Enhancement Algorithm (KCEA), it attempts to enhance initial coverage, and achieve the required K-coverage degree for a specific application efficiently. Simulation results show that the proposed algorithm achieves coverage improvement of 5.34% compared to K-Coverage Rate Deployment (K-CRD), which achieves 1.31% when deploying one additional sensor. Moreover, the proposed algorithm is more time efficient.Keywords: Wireless Sensor Networks (WSN), harmony search algorithms, K-Coverage, Mobile WSN
Procedia PDF Downloads 5152278 An Investigation of E-Government by Using GIS and Establishing E-Government in Developing Countries Case Study: Iraq
Authors: Ahmed M. Jamel
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Electronic government initiatives and public participation to them are among the indicators of today's development criteria of the countries. After consequent two wars, Iraq's current position in, for example, UN's e-government ranking is quite concerning and did not improve in recent years, either. In the preparation of this work, we are motivated with the fact that handling geographic data of the public facilities and resources are needed in most of the e-government projects. Geographical information systems (GIS) provide most common tools not only to manage spatial data but also to integrate such type of data with nonspatial attributes of the features. With this background, this paper proposes that establishing a working GIS in the health sector of Iraq would improve e-government applications. As the case study, investigating hospital locations in Erbil is chosen.Keywords: e-government, GIS, Iraq, Erbil
Procedia PDF Downloads 3802277 Intelligent Driver Safety System Using Fatigue Detection
Authors: Samra Naz, Aneeqa Ahmed, Qurat-ul-ain Mubarak, Irum Nausheen
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Driver safety systems protect driver from accidents by sensing signs of drowsiness. The paper proposes a technique which can detect the signs of drowsiness and make corresponding decisions to make the driver alert. This paper presents a technique in which the driver will be continuously monitored by a camera and his eyes, head and mouth movements will be observed. If the drowsiness signs are detected on the basis of these three movements under the predefined criteria, driver will be declared as sleepy and he will get alert with the help of alarms. Three robust techniques of drowsiness detection are combined together to make a robust system that can prevent form accident.Keywords: drowsiness, eye closure, fatigue detection, yawn detection
Procedia PDF Downloads 2862276 Mechanical Ventilation: Relationship between Body Mass Index and Selected Patients' Outcomes at a University Hospital in Cairo
Authors: Mohamed Mamdouh Al-Banna, Warda Youssef Mohamed Morsy, Hanaa Ali El-Feky, Ashraf Hussein Abdelmohsen
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Background: The mechanically ventilated patients need a special nursing care with continuous closed observation. The patients’ body mass index may affect their prognosis or outcomes. Aim of the study: to investigate the relationship between BMI and selected outcomes of critically ill mechanically ventilated patients. Research Design: A descriptive correlational research design was utilized Research questions: a) what is the BMI profile of mechanically ventilated patients admitted to critical care units over a period of six months? b) What is the relationship between body mass index and frequency of organ dysfunction, length of ICU stay, weaning from mechanical ventilation, and the mortality rate among adult critically ill mechanically ventilated patients? Setting: different intensive care units of Cairo University Hospitals. Sample: A convenience sample of 30 mechanically ventilated patients for at least 72 hours. Tools of data collection: Three tools were utilized to collect data pertinent to the current study: tool 1: patients’ sociodemographic and medical data sheet, tool 2: BURNS Wean Assessment Program (BWAP) checklist, tool 3: Sequential organ failure assessment (SOFA score) sheet. Results: The majority of the studied sample (77%) was males, and (26.7 %) of the studied sample were in the age group of 18-28 years old, and (26.7 %) were in the age group of 40-50 years old. Moreover, two thirds (66.7%) of the studied sample were within normal BMI. No significant statistical relationship between BMI category and ICU length of stay or the mortality rate among the studied sample, (X² = 11.31, P value = 0.79), (X² = 0.15, P value = 0.928) respectively. No significant statistical relationship between BMI category and the weaning trials from mechanical ventilation among the studied sample, (X² = 0.15, P value = 0.928). No significant statistical relationship was found between BMI category and the occurrence of organ dysfunction among the studied sample, (X² = 2.54, P value = 0.637). Conclusion: No relationship between the BMI categories and the selected patients’ outcomes (weaning from MV, length of ICU stay, occurrence of organ dysfunction, mortality rate). Recommendations: Replication of this study on a larger sample from different geographical locations in Arab Republic of Egypt, conducting farther studies to assess the effect of the quality of nursing care on the mechanically ventilated patients’ outcomes.Keywords: mechanical ventilation, body mass index, outcomes of mechanically ventilated patient, organ failure
Procedia PDF Downloads 2422275 Effect of Aryl Imidazolium Ionic Liquids as Asphaltene Dispersants
Authors: Raghda Ahmed El-Nagar
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Oil spills are one of the most serious environmental issues that have occurred during the production and transportation of petroleum crude oil. Chemical asphaltene dispersants are hazardous to the marine environment, so Ionic liquids (ILs) as asphaltene dispersants are a critical area of study. In this work, different aryl imidazolium ionic liquids were synthesized with high yield and elucidated via tools of analysis (Elemental analysis, FT-IR, and 1H-NMR). Thermogravimetric analysis confirmed that the prepared ILs posses high thermal stability. The critical micelle concentration (CMC), surface tension, and emulsification index were investigated. Evaluation of synthesized ILs as asphaltene dispersants were assessed at various concentrations, and data reveals high dispersion efficiency.Keywords: ionic liquids, oil spill, asphaltene dispersants, CMC, efficiency
Procedia PDF Downloads 1812274 Calculation of Lungs Physiological Lung Motion in External Lung Irradiation
Authors: Yousif Mohamed Y. Abdallah, Khalid H. Eltom
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This is an experimental study deals with measurement of the periodic physiological organ motion during lung external irradiation in order to reduce the exposure of healthy tissue during radiation treatments. The results showed for left lung displacement reading (4.52+1.99 mm) and right lung is (8.21+3.77 mm) which the radiotherapy physician should take suitable countermeasures in case of significant errors. The motion ranged between 2.13 mm and 12.2 mm (low and high). In conclusion, the calculation of tumour mobility can improve the accuracy of target areas definition in patients undergo Sterostatic RT for stage I, II and III lung cancer (NSCLC). Definition of the target volume based on a high resolution CT scan with a margin of 3-5 mm is appropriate.Keywords: physiological motion, lung, external irradiation, radiation medicine
Procedia PDF Downloads 4082273 Industrial Engineering Higher Education in Saudi Arabia: Assessing the Current Status
Authors: Mohammed Alkahtani, Ahmed El-Sherbeeny
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Industrial engineering is among engineering disciplines that have been introduced relatively recently to higher education in Saudi Arabian engineering colleges. The objective of this paper is to shed light on the history and status of IE higher education in different Saudi universities, including statistics comparing student enrollment and graduation in different Saudi public and private universities. This paper then proposes how industrial engineering programs could participate successfully in the Saudi Vision 2030. Finally, the authors show the results of a survey conducted on a number of IE students evaluating various academic and administrative aspects of the IE program at King Saud University.Keywords: higher education, history, industrial engineering, Vision 2030
Procedia PDF Downloads 3062272 The Effect of the Crystal Field Interaction on the Critical Temperatures and the Sublattice Magnetizations of a Mixedspin-3/2 and Spin-5/2 Ferromagnetic System
Authors: Fathi Abubrig, Mohamed Delfag, Suad Abuzariba
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The influence of the crystal field interactions on the mixed spin-3/2 and spin-5/2 ferromagnetic Ising system is considered by using the mean field theory based on Bogoliubov inequality for the Gibbs free energy. The ground-state phase diagram is constructed, the phase diagrams of the second-order critical temperatures are obtained, and the thermal variation of the sublattice magnetizations is investigated in detail. We find some interesting phenomena for the sublattice magnetizations at particular values of the crystal field interactions.Keywords: crystal field, Ising system, ferromagnetic, magnetization, phase diagrams
Procedia PDF Downloads 4782271 QSAR Study and Haptotropic Rearrangement in Estradiol Derivatives
Authors: Mohamed Abd Esselem Dems, Souhila Laib, Nadjia Latelli, Nadia Ouddai
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In this work, we have developed QSAR model for Relative Binding Affinity (RBA) of a large diverse set of estradiol among these derivatives, the organometallic derivatives. By dividing the dataset into a training set of 24 compounds and a test set of 6 compounds. The DFT method was used to calculate quantum chemical descriptors and physicochemical descriptors (MR and MLOGP) were performed using E-Dragon. All the validations indicated that the QSAR model built was robust and satisfactory (R2 = 90.12, Q2LOO = 86.61, RMSE = 0.272, F = 60.6473, Q2ext =86.07). We have therefore apply this model to predict the RBA, for two isomers β and α wherein Mn(CO)3 complex with the aromatic ring of estradiol, and the two isomers show little appreciation for the estrogenic receptor (RBAβ = 1.812 and RBAα = 1.741).Keywords: DFT, estradiol, haptotropic rearrangement, QSAR, relative binding affinity
Procedia PDF Downloads 2832270 Geometrical Based Unequal Droplet Splitting Using Microfluidic Y-Junction
Authors: Bahram Talebjedi, Amirmohammad Sattari, Ahmed Zoher Sihorwala, Mina Hoorfar
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Among different droplet manipulations, controlled droplet-splitting is of great significance due to its ability to increase throughput and operational capability. Furthermore, unequal droplet-splitting can provide greater flexibility and a wider range of dilution factors. In this study, we developed two-dimensional, time-dependent complex fluid dynamics simulations to model droplet formation in a flow focusing device, followed by splitting in a Y-shaped junction with sub-channels of unequal widths. From the results obtained from the numerical study, we correlated the diameters of the droplets in the sub-channels to the Weber number, thereby demarcating the droplet splitting and non-splitting regimes.Keywords: microfluidics, unequal droplet splitting, two phase flow, flow focusing device
Procedia PDF Downloads 1582269 Qualitative Risk Assessment of Rift Valley Fever Vaccine Production
Authors: Mohammed E. Mansour, Tamador M. A. Elhassan, Nahid A. Ibrahim, Awatif A. Ahmed, Manal A. Abdalla
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Rift valley fever (RVF) is mosquito-borne disease. RVF is transboundary zoonotic disease. It has socioeconomic and public health importance. This paper describes qualitative risk of the RVF vaccine production. RVF is endemic in the Sudan. It has been reported in Sudan due to abundance of Ades Eqytie. Thus, there is huge effort to control it. Vaccination practices had significant role to control and manage RVF. The risk assessment explains the likelihood of a risk as likely. Thus, insecticides and repellents synergize the effort of the vaccination.Keywords: qualitative analysis, risk assessment, rift valley fever vaccine, quality control
Procedia PDF Downloads 5012268 Conformational Switch of hRAGE upon Self-Association
Authors: Ikhlas Ahmed, Jamillah Zamoon
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The human receptor for advanced glycation end product is a plasma membrane receptor with an intrinsically disordered region. The protein consists of three extracellular domains, a single membrane spanning transmembrane domain, and a cytosolic domain which is intrinsically disordered and responsible for signaling. The disordered nature of the cytosolic domain allows it to be dynamic in solution. This receptor self-associates to higher forms. The association is triggered by ligand, metal or by the extracellular domain. Fluorescence spectroscopy technique is used to test the self-association of the different concentrations of the cytosolic domain. This work has concluded that the cytosolic domain of this receptor also self-associates. Moreover, the self-association does not require ligand or metal.Keywords: fluorescence spectroscopy, hRAGE, IDP, Self-association
Procedia PDF Downloads 3522267 Experimental Investigation and Numerical Simulations of the Cylindrical Machining of a Ti-6Al-4V Tree
Authors: Mohamed Sahli, David Bassir, Thierry Barriere, Xavier Roizard
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Predicting the behaviour of the Ti-6Al-4V alloy during the turning operation was very important in the choice of suitable cutting tools and also in the machining strategies. In this study, a 3D model with thermo-mechanical coupling has been proposed to study the influence of cutting parameters and also lubrication on the performance of cutting tools. The constants of the constitutive Johnson-Cook model of Ti-6Al-4V alloy were identified using inverse analysis based on the parameters of the orthogonal cutting process. Then, numerical simulations of the finishing machining operation were developed and experimentally validated for the cylindrical stock removal stage with the finishing cutting tool.Keywords: titanium turning, cutting tools, FE simulation, chip
Procedia PDF Downloads 166