Search results for: Mohamad Saleh Sangin Ostadi
410 Transition of Nutrition Style and Obesity: A Kuwaiti Case Study
Authors: Othman Saleh Al-Razgan
Abstract:
Obesity establishes an epidemic along with an array of comorbidities and this call for careful clinical assessment, to identify causal factors and comprehensive management. In Kuwait, this epidemic reflects the progressive, socio-economic and age-related issues, along with the shift of nutrition from traditional to modern-style. The current research attempts to narrate the obesity and related health issues in Kuwait, with a special emphasis on the magnitude of the issue in Kuwait, nutrition transition over the past three decades, change in life-style, and possible solution for this issue.Keywords: clinical assessment, comorbidities, obesity, socio-economic
Procedia PDF Downloads 438409 Dielectrophoretic Characterization of Tin Oxide Nanowires for Biotechnology Application
Authors: Ahmad Sabry Mohamad, Kai F. Hoettges, Michael Pycraft Hughes
Abstract:
This study investigates nanowires using Dielectrophoresis (DEP) in non-aqueous suspension of Tin (IV) Oxide (SnO2) nanoparticles dispersed in N,N-dimenthylformamide (DMF). The self assembly of nanowires in DEP impedance spectroscopy can be determined. In this work, dielectrophoretic method was used to measure non-organic molecules for estimating the permittivity and conductivity characteristic of the nanowires. As in aqueous such as salt solution has been dominating the transport of SnO2, which are the wire growth threshold, depend on applied voltage. While DEP assembly of nanowires depend on applied frequency, the applications of dielectrophoretic collection are measured using impedance spectroscopy.Keywords: dielectrophoresis, impedance spectroscopy, nanowires, N, N-dimenthylformamide, SnO2
Procedia PDF Downloads 658408 A Study of Families of Bistar and Corona Product of Graph: Reverse Topological Indices
Authors: Gowtham Kalkere Jayanna, Mohamad Nazri Husin
Abstract:
Graph theory, chemistry, and technology are all combined in cheminformatics. The structure and physiochemical properties of organic substances are linked using some useful graph invariants and the corresponding molecular graph. In this paper, we study specific reverse topological indices such as the reverse sum-connectivity index, the reverse Zagreb index, the reverse arithmetic-geometric, and the geometric-arithmetic, the reverse Sombor, the reverse Nirmala indices for the bistar graphs B (n: m) and the corona product Kₘ∘Kₙ', where Kₙ' Represent the complement of a complete graph Kₙ.Keywords: reverse topological indices, bistar graph, the corona product, graph
Procedia PDF Downloads 94407 Poly Urea-Formaldehyde for Preconcentration and Determination of Cadmium Ion in Environmental Samples
Authors: Homayon Ahmad Panahi, Samira Tajik, Mohamad Hadi Dehghani, Mostafa Khezri, Elham Moniri
Abstract:
In this research, poly urea-formaldehyde was prepared. The poly urea-formaldehyde was characterized by fourier transform infra-red spectroscopy. Then the effects of various parameters on Cd (II) sorption such as pH, contact time were studied. The optimum pH value for sorption of Cd(II) was 5.5. The sorption capacity of poly urea-formaldehyde for Cd (II) were 76.3 mg g−1. A Cd (II) removal of 55% was obtained. The profile of Cd (II) uptake on this sorbent reflects good accessibility of the chelating sites in the poly urea-formaldehyde. The developed method was utilized for determination of Cd (II) in environmental water samples by flame atomic absorption spectrometry with satisfactory results.Keywords: poly urea-formaldehyde, cadmium ion, environmental sample, determination
Procedia PDF Downloads 545406 Diagnosis of Static Eccentricity in 400 kW Induction Machine Based on the Analysis of Stator Currents
Authors: Saleh Elawgali
Abstract:
Current spectrums of a four pole-pair, 400 kW induction machine were calculated for the cases of full symmetry and static eccentricity. The calculations involve integration of 93 electrical plus four mechanical ordinary differential equations. Electrical equations account for variable inductances affected by slotting and eccentricities. The calculations were followed by Fourier analysis of the stator currents in steady state operation. Zooms of the current spectrums, around the 50 Hz fundamental harmonic as well as of the main slot harmonic zone, were included. The spectrums included refer to both calculated and measured currents.Keywords: diagnostic, harmonic, induction machine, spectrum
Procedia PDF Downloads 520405 Location Quotient Analysis: Case Study
Authors: Seyed Habib A. Rahmati, Mohamad Hasan Sadeghpour, Parsa Fallah Sheikhlari
Abstract:
Location quotient (LQ) is a comparison technique that represents emphasized economic structure of single zone versus the standard area to identify specialty for every zone. In another words, the exact calculation of this metric can show the main core competencies and critical capabilities of an area to the decision makers. This research focus on the exact calculation of the LQ for an Iranian Province called Qazvin and within a case study introduces LQ of the capable industries of Qazvin. Finally, through different graphs and tables, it creates an opportunity to compare the recognized capabilities.Keywords: location quotient, case study, province analysis, core competency
Procedia PDF Downloads 653404 Enhancement of the Performance of Al-Qatraneh 33-kV Transmission Line Using STATCOM: A Case Study
Authors: Ali Hamad, Ibrahim Al-Drous, Saleh Al-Jufout
Abstract:
This paper presents a case study of using STATCOM to enhance the performance of Al-Qatraneh 33-kV transmission line. The location of the STATCOM was identified maintaining minimum voltage drops at the 110 load nodes. The transmission line and the 110 load nodes have been modeled by MATLAB/Simulink. The suggested STATCOM and its location will increase the transmission capability of this transmission line and overcome the overload expected in the year 2020. The annual percentage loading rise has been considered as 14%. A graphical representation of the line voltages and the voltage drops at different load nodes has been illustrated.Keywords: FACTS, MATLAB, STATCOM, transmission line, voltage drop
Procedia PDF Downloads 440403 The Role of Capitalism, Society, and Media in the Rise of Plastic Surgeries in Egypt
Authors: Rana Saleh
Abstract:
This study explores the introduction and rise of plastic surgery in Egypt, tracing its historical roots and examining its growing prevalence in modern society. Through a qualitative review of existing literature, the research investigates how media, capitalism, and patriarchal societal structures contribute to the normalization of cosmetic surgeries, particularly among women. It delves into the consumer culture created by capitalism and the sexualization of women’s bodies, emphasizing how these factors influence women's perceptions of beauty and their decisions to undergo surgery. The paper also highlights the role of patriarchy in shaping these choices within Egypt’s collectivist society.Keywords: plastic surgery, Egypt, media, capitalism, sexualization of women’s bodies
Procedia PDF Downloads 12402 Development of Femoral Head Osteonecrosis Due to Corticosteroids Consumption; Probable Role of OCP: A Case Report
Authors: S. Alireza Mirghasemi, Shervin Rashidinia, Mohammad Saleh Sadeghi, Mohsen Talebizadeh, Narges Rahimi Gabaran, Seyed Shahin Eftekhari, Sara Shahmoradi
Abstract:
Avascular necrosis of femoral head is a pathologic condition that the main cause is decreased blood supply of femoral head. Among predisposing risk factors, chronic use of corticosteroids, alcoholism, smocking and hip traumas have more important role. Also we can mention OCP consumption as a risk factor among less common predisposing factors that lead to AVNF, in this study we introduce another cause of AVNF with a period of treatment with moderate dose of corticosteroids accompanied by OCP as a probable facilitating factor that leads to AVNF.Keywords: AVN, corticosteroids consumption, femoral head osteonecrosis, OCP
Procedia PDF Downloads 464401 Evaluation of Musical Conductor Exposure to Noise
Authors: Ahmed Saleh Summan
Abstract:
This article presents the results of a technical report on the evaluation of occupational noise exposures among a musical conductor in a musical rehearsal hall (party–center). A calibrated noise dosimeter was used to measure the personal exposure of a music teacher/conductor for 8 hours in two days of rehearsal involving 90 players. Results showed that noise exposure levels were much higher than the permissible levels regulated 85dBA/8hr by NIOSH. In fact, the first day of measurements recorded the highest exposure levels (91 dBA). A number of factors contributed to these results, such as players number, types of instruments used, and activities. Noise control measures were recommended to solve this situation.Keywords: noise exposure, music conductors, occupational noise, noise in rooms
Procedia PDF Downloads 113400 Contemporary Visual Art and Shariah: A Conceptual Framework
Authors: Ishak Ramli, Mohamad Noorman Masrek, Muhamad Abdul Aziz Ab Gani
Abstract:
Islam places restrictions and limitation to the creation and ownership of visual art. Not all forms of visual arts are permissible in Islam. However, guidance on the creation and ownership of visual arts is not made plain and clear not only to the Islamic followers but also to the art community. Given this gap, this study attempts to develop a conceptual framework that will guide artist and art collectors on what constitute to valid and acceptable through the Islamic perspective. Based on this framework, several research checklist are proposed. It is highly useful especially for the researchers who are interested to study the topic. Qualitative research is the best choice to test run the paper work to attempt all the checklist which are formed.Keywords: contemporary visual art, Shariah, conceptual framework, Islam
Procedia PDF Downloads 379399 Preliminary Results on a Maximum Mean Discrepancy Approach for Seizure Detection
Authors: Boumediene Hamzi, Turky N. AlOtaiby, Saleh AlShebeili, Arwa AlAnqary
Abstract:
We introduce a data-driven method for seizure detection drawing on recent progress in Machine Learning. The method is based on embedding probability measures in a high (or infinite) dimensional reproducing kernel Hilbert space (RKHS) where the Maximum Mean Discrepancy (MMD) is computed. The MMD is metric between probability measures that are computed as the difference between the means of probability measures after being embedded in an RKHS. Working in RKHS provides a convenient, general functional-analytical framework for theoretical understanding of data. We apply this approach to the problem of seizure detection.Keywords: kernel methods, maximum mean discrepancy, seizure detection, machine learning
Procedia PDF Downloads 236398 Powdered Beet Red Roots Using as Adsorbent to Removal of Methylene Blue Dye from Aqueous Solutions
Authors: Abdulali Bashir Ben Saleh
Abstract:
The powdered beet red roots (PBRR) were used as an adsorbent to remove dyes namely methylene blue dye (as a typical cationic or basic dye) from aqueous solutions. The present study shows that used beet red roots powder exhibit adsorption trend for the dye. The adsorption processes were carried out at various conditions of concentrations, processing time and a wide range of pH between 2.5-11. Adsorption isotherm equations such as Freundlich, and Langmuir were applied to calculate the values of respective constants. Adsorption study was found that the currently introduced adsorbent can be used to remove cationic dyes such as methylene blue from aqueous solutions.Keywords: beet red root, removal of deys, methylene blue, adsorption
Procedia PDF Downloads 331397 Phytoremediation Potential of Tomato for Cd and Cr Removal from Polluted Soils
Authors: Jahanshah Saleh, Hossein Ghasemi, Ali Shahriari, Faezeh Alizadeh, Yaaghoob Hosseini
Abstract:
Cadmium and chromium are toxic to most organisms and different mechanisms have been developed for overcoming with the toxic effects of these heavy metals. We studied the uptake and distribution of cadmium and chromium in different organs of tomato (Lycopersicon esculentum L.) plants in nine heavy metal polluted soils in western Hormozgan province, Iran. The accumulation of chromium was in increasing pattern of fruit peelKeywords: cadmium, chromium, phytoextraction, phytostabilization, tomato
Procedia PDF Downloads 343396 Experimental Analysis of Tuned Liquid Damper (TLD) with Embossments Subject to Random Excitation
Authors: Mohamad Saberi, Arash Sohrabi
Abstract:
Tuned liquid damper is one the passive structural control ways which has been used since mid-1980 decade for seismic control in civil engineering. This system is made of one or many tanks filled with fluid, mostly water that installed on top of the high raised structure and used to prevent structure vibration. In this article we will show how to make seismic table contain TLD system and analysis the result of using this system in our structure. Results imply that when frequency ratio approaches 1 this system can perform its best in both dissipate energy and increasing structural damping. And also results of these serial experiments are proved compatible with Hunzer linear theory behaviour.Keywords: TLD, seismic table, structural system, Hunzer linear behaviour
Procedia PDF Downloads 377395 Buzan Mind Mapping: An Efficient Technique for Note-Taking
Authors: T. K. Tee, M. N. A. Azman, S. Mohamed, M. Muhammad, M. M. Mohamad, J. Md Yunos, M. H. Yee, W. Othman
Abstract:
Buzan mind mapping is an efficient system of note-taking that makes revision a fun thing to do for students. Tony Buzan has been teaching children all over the world for the past thirty years and has proved that mind maps are the magic formula in the classroom for everyone. The purpose of this paper is to discuss the importance of Buzan mind mapping as a note-taking technique for the secondary school students. This paper also examines the mind mapping technique, advantages and disadvantages of hand-drawn mind maps. Samples of students’ mind maps were presented and discussed.Keywords: Buzan mind mapping, note-taking technique, hand-drawn, mind maps
Procedia PDF Downloads 537394 Comparative Assessment of ABS and Disk Brake Systems
Authors: Saleh Mobasseri, Mohammad Mobasseri
Abstract:
The article refers to the history of the rise of brake system and described it’s importance in passenger’s lives. The disc brake system performance and ABS are also compared with each other by the kinetic and kinematic analysis of the braking system,and evaluate the impact of each parameters is checked on the vehicle stopping distance. Anti−lock braking system (ABS) is one of the most important features that affect on vehicle safety and for this reason much efforts have been made to improve this system. The objectives of the anti−lock system (ABS) are as follows: Preventing the wheels from locking, achieving maximum technical momentum in terms of braking,stability,reducing stopping distances. In this paper,we study the comparative of ABS brake and disc brake.Keywords: anti−lock braking System (ABS), stopping distances, booster, car stability, force exerted on the brake pedal
Procedia PDF Downloads 396393 Performance Study of ZigBee-Based Wireless Sensor Networks
Authors: Afif Saleh Abugharsa
Abstract:
The IEEE 802.15.4 standard is designed for low-rate wireless personal area networks (LR-WPAN) with focus on enabling wireless sensor networks. It aims to give a low data rate, low power consumption, and low cost wireless networking on the device-level communication. The objective of this study is to investigate the performance of IEEE 802.15.4 based networks using simulation tool. In this project the network simulator 2 NS2 was used to several performance measures of wireless sensor networks. Three scenarios were considered, multi hop network with a single coordinator, star topology, and an ad hoc on demand distance vector AODV. Results such as packet delivery ratio, hop delay, and number of collisions are obtained from these scenarios.Keywords: ZigBee, wireless sensor networks, IEEE 802.15.4, low power, low data rate
Procedia PDF Downloads 432392 Vitamin D and Prevention of Rickets in Children
Authors: Mousa Saleh Daoud
Abstract:
Rickets is a condition that affects the development of bones in children. It causes soft bones, which can become bowed or curved, this bending and curvature is evident in the age of Walking. The most common cause of rickets is dietary deficiency of vitamin D or Lack of exposure to sunlight or both together. The link between vitamin D and rickets has been known for many years and is well understood by doctors and scientists. If a child does not get enough of the vitamin D, the bones cannot form hard outer shells. This is why they become soft and weak. This study was conducted on children who reviewed by our medical clinic between the years 2011-2013. The study included 400 children, aged between one and six years. 11 children had clear clinical manifestations of rickets of varying degrees and all of them due to lack of vitamin D except for one case of rickets resistant to vitamin D. 389 cases ranged between natural and deficiency in vitamin D without clinical manifestations of Rickets.Keywords: rickts, bone metabolic diseases, vitamin D, child
Procedia PDF Downloads 409391 Experimental Analysis of Tuned Liquid Damper (TLD) for High Raised Structures
Authors: Mohamad Saberi, Arash Sohrabi
Abstract:
Tuned liquid damper is one the passive structural control ways which has been used since mid-1980 decade for seismic control in civil engineering. This system is made of one or many tanks filled with fluid, mostly water that installed on top of the high raised structure and used to prevent structure vibration. In this article, we will show how to make seismic table contain TLD system and analysis the result of using this system in our structure. Results imply that when frequency ratio approaches 1 this system can perform its best in both dissipate energy and increasing structural damping. And also results of these serial experiments are proved compatible with Hunzer linear theory behaviour.Keywords: TLD, seismic table, structural system, Hunzer linear behaviour
Procedia PDF Downloads 333390 Clustering of Extremes in Financial Returns: A Comparison between Developed and Emerging Markets
Authors: Sara Ali Alokley, Mansour Saleh Albarrak
Abstract:
This paper investigates the dependency or clustering of extremes in the financial returns data by estimating the extremal index value θ∈[0,1]. The smaller the value of θ the more clustering we have. Here we apply the method of Ferro and Segers (2003) to estimate the extremal index for a range of threshold values. We compare the dependency structure of extremes in the developed and emerging markets. We use the financial returns of the stock market index in the developed markets of US, UK, France, Germany and Japan and the emerging markets of Brazil, Russia, India, China and Saudi Arabia. We expect that more clustering occurs in the emerging markets. This study will help to understand the dependency structure of the financial returns data.Keywords: clustring, extremes, returns, dependency, extermal index
Procedia PDF Downloads 404389 Reliability Analysis of Partial Safety Factor Design Method for Slopes in Granular Soils
Authors: K. E. Daryani, H. Mohamad
Abstract:
Uncertainties in the geo-structure analysis and design have a significant impact on the safety of slopes. Traditionally, uncertainties in the geotechnical design are addressed by incorporating a conservative factor of safety in the analytical model. In this paper, a risk-based approach is adopted to assess the influence of the geotechnical variable uncertainties on the stability of infinite slopes in cohesionless soils using the “partial factor of safety on shear strength” approach as stated in Eurocode 7. Analyses conducted using Monte Carlo simulation show that the same partial factor can have very different levels of risk depending on the degree of uncertainty of the mean values of the soil friction angle and void ratio.Keywords: Safety, Probability of Failure, Reliability, Infinite Slopes, Sand.
Procedia PDF Downloads 572388 Exploring Peculiarities of a Leadership Style of Non-governmental Organization (NGO): Case of Six Non-governmental Organizations Based in Lebanon
Authors: Nour Mohamad Fayad
Abstract:
This study aims to investigate and explore the peculiarities of the leadership style of NGOs based in Lebanon. This study is supported by empirical testing that considers the case of Embrace and other NGOs performing in Lebanese society. Throughout this study researcher demonstrated leadership characteristics, styles, and competencies and demonstrated the evolvement of leadership in recent years. Moreover, this study sheds light on the different NGO leaders and exhibits the exceptional obstacles, on both personal and professional aspects and applies it to the Lebanese society by collecting primary data from 6 NGOs. The findings indicate that there is a positive correlation between peculiarities of leadership style and the performance of NGOs, but this is not consistent across all NGOs in Lebanese societies.Keywords: leadership, peculiarities, NGOs, embrace, Lebanon
Procedia PDF Downloads 85387 Systems Integrated Approach to Improve the Design and Construction of Green Buildings
Authors: Saleh Hayat
Abstract:
Efficiency, productivity and sustainability are important factors for structure and the application of processes in green building. Various previous studies have addressed efficiency, productivity and sustainability separately. This research study aims to investigate the implications of these three factors taking together. Frequency analysis and the ranking techniques are carried out to explore the connection between these factors. The interconnection matrix has been developed and functional grouping is made based upon data from expert opinion and field professionals. The existence of a relationship, the type of relationship and the scaled impact have been drawn. Additionally, a system diagram has been developed to show the variable correlation. The results of expert opinion show that efficiency, productivity and sustainability have a stronger impact on green buildings.Keywords: efficiency, green building, productivity, sustainability
Procedia PDF Downloads 135386 Text Mining Techniques for Prioritizing Pathogenic Mutations in Protein Families Known to Misfold or Aggregate
Authors: Khaleel Saleh Al-Rababah
Abstract:
Amyloid fibril forming regions, which are known as protein aggregates, in sequences of some protein families are associated with a number of diseases known as amyloidosis. Mutations play a role in forming fibrils by accelerating the fibril formation process. In this paper we want to extract diseases that caused by those mutations as a result of the impact of the mutations on structural and functional properties of the aggregated protein. We propose a text mining system, to automatically extract mutations, diseases and relations between mutations and diseases. We presented an algorithm based on finite state to cluster mutations found in the same sentence as a sentence could contain different mutation cause different diseases. Also, we presented a co reference algorithm that enables cross-link sentences.Keywords: amyloid, amyloidosis, co reference, protein, text mining
Procedia PDF Downloads 521385 Thiosemicarbazone Derived from 4-Aminoantipyrine as Corrosion Inhibitor
Authors: Ahmed A. Al-Amiery, Yasmin K. Al-Majedy, Abdul Amir H. Kadhum, Abu Bakar Mohamad
Abstract:
The efficiency of synthesized thiosemicarbazone namely 2-(1,5-dimethyl-4-(2-methylbenzylidene)amino)-2-phenyl-1H-pyrazol-3(2H)-ylidene) hydrazinecarbothioamide investigated as corrosion inhibitor of mild steel in 1N H2SO4 using electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization (PD) in addition of scanning electron microscopy (SEM). The results showed that this inhibitor behaved as a good corrosion inhibitor even at low concentration with a mean efficiency of 93%. Polarization technique and EIS were tested in different concentrations reveal that this compound is adsorbed on the mild steel, therefore blocking the active sites and the adsorption follows the Langmuir adsorption isotherm model. SEM shows that mild steel surface is nearly perfect for mild steel which was immersed in a solution of H2SO4 with corrosion inhibitor.Keywords: corrosion inhibitor, thiosemicarbazide, electrochemical impedance, electrochemical impedance spectroscopy
Procedia PDF Downloads 519384 The Method for Synthesis of Chromium Oxide Nano Particles as Increasing Color Intensity on Industrial Ceramics
Authors: Bagher Aziz Kalantari, Javad Rafiei, Mohamad Reza Talei Bavil Olyai
Abstract:
Disclosed is a method of preparing a pigmentary chromium oxide nano particles having 50 percent particle size less than about 100nm. According to the disclosed method, a substantially dry solid composition of potassium dichromate and carbon active is heated in CO2 atmosphere to a temperature of about 600ºc for 1hr. Thereafter, the solid Cr2O3 product was washed twice with distilled water. The other aim of this study is to assess both the colouring performance and the potential of nano-pigments in the ceramic tile decoration. The rationable consists in nano-pigment application in several ceramics, including a comparison of colour performance with conventional micro-pigments.Keywords: green chromium oxide, nano particles, colour performances, particle size
Procedia PDF Downloads 333383 Silent Myocardial Infarction Presented with Homonymous Hemianopia in a Non-Diabetic Middle Aged Man
Authors: Seyed Fakhroddin Hejazi, Mohammad Saleh Sadeghi, Leili Iranirad
Abstract:
Silent myocardial infarction is defined as the appearance of pathological Q waves in the electrocardiogram, without objective signs of myocardial infarction and any minimal or atypical symptoms. Although this condition has been known for a long time, but little is known about its phenomenon and the mechanisms of it remain unclear. Its coincidence with stroke is also still controversial. This case report introduces a middle-aged man with silent myocardial infarction presented with homonymous hemianopia, which except stage 1 hypertension, had no other major cardiovascular risk factors including diabetes mellitus, hypercholesterolemia, family history of cardiac diseases and smoking. In conclusion, this case report indicated that existence of only one cardiovascular risk factor would lead to the development of MI or stroke.Keywords: silent myocardial infarction, homonymous hemianopia, stroke, hypertension
Procedia PDF Downloads 286382 Neuroprotection against N-Methyl-D-Aspartate-Induced Optic Nerve and Retinal Degeneration Changes by Philanthotoxin-343 to Alleviate Visual Impairments Involve Reduced Nitrosative Stress
Authors: Izuddin Fahmy Abu, Mohamad Haiqal Nizar Mohamad, Muhammad Fattah Fazel, Renu Agarwal, Igor Iezhitsa, Nor Salmah Bakar, Henrik Franzyk, Ian Mellor
Abstract:
Glaucoma is the global leading cause of irreversible blindness. Currently, the available treatment strategy only involves lowering intraocular pressure (IOP); however, the condition often progresses despite lowered or normal IOP in some patients. N-methyl-D-aspartate receptor (NMDAR) excitotoxicity often occurs in neurodegeneration-related glaucoma; thus it is a relevant target to develop a therapy based on neuroprotection approach. This study investigated the effects of Philanthotoxin-343 (PhTX-343), an NMDAR antagonist, on the neuroprotection of NMDA-induced glaucoma to alleviate visual impairments. Male Sprague-Dawley rats were equally divided: Groups 1 (control) and 2 (glaucoma) were intravitreally injected with phosphate buffer saline (PBS) and NMDA (160nM), respectively, while group 3 was pre-treated with PhTX-343 (160nM) 24 hours prior to NMDA injection. Seven days post-treatments, rats were subjected to visual behavior assessments and subsequently euthanized to harvest their retina and optic nerve tissues for histological analysis and determination of nitrosative stress level using 3-nitrotyrosine ELISA. Visual behavior assessments via open field, object, and color recognition tests demonstrated poor visual performance in glaucoma rats indicated by high exploratory behavior. PhTX-343 pre-treatment appeared to preserve visual abilities as all test results were significantly improved (p < 0.05). H&E staining of the retina showed a marked reduction of ganglion cell layer thickness in the glaucoma group; in contrast, PhTX-343 significantly increased the number by 1.28-folds (p < 0.05). PhTX-343 also increased the number of cell nuclei/100μm2 within inner retina by 1.82-folds compared to the glaucoma group (p < 0.05). Toluidine blue staining of optic nerve tissues showed that PhTX-343 reduced the degeneration changes compared to the glaucoma group which exhibited vacuolation overall sections. PhTX-343 also decreased retinal 3- nitrotyrosine concentration by 1.74-folds compared to the glaucoma group (p < 0.05). All results in PhTX-343 group were comparable to control (p > 0.05). We conclude that PhTX-343 protects against NMDA-induced changes and visual impairments in the rat model by reducing nitrosative stress levels.Keywords: excitotoxicity, glaucoma, nitrosative stress , NMDA receptor , N-methyl-D-aspartate , philanthotoxin, visual behaviour
Procedia PDF Downloads 135381 Nickel and Chromium Distributions in Soil and Plant Influenced by Geogenic Sources
Authors: Mohamad Sakizadeh, Fatemeh Mehrabi Sharafabadi, Hadi Ghorbani
Abstract:
Concentrations of Cr and Ni in 97 plant samples (belonged to eight different plant species) and the associated soil groups were considered in this study. The amounts of Ni in soil groups fluctuated between 26.8 and 36.8 mgkg⁻¹ whereas the related levels of chromium ranged from 67.7 to 94.3mgkg⁻¹. The index of geoaccumulation indicated that 87 percents of the studied soils for chromium and 98.8 percents for nickel are located in uncontaminated zone. The results of Mann-Whitney U-test proved that agricultural practices have not significantly influenced the values of Ni and Cr. In addition, tillage had also little impact on the Ni and Cr transfer in the surface soil. Ni showed higher accumulation and soil-to-plant transfer factor compared with that of chromium in the studied plants. There was a high similarity between the accumulation pattern of Cr and Fe in most of the plant species.Keywords: bioconcentration factor, chromium, geoaccumulation index, nickel
Procedia PDF Downloads 355