Search results for: Raja Arslan Ahmad Khan
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 1887

Search results for: Raja Arslan Ahmad Khan

1407 Efficient Management of Construction Logistics: A Challenge to Both Conventional and Technological Systems in the Developing Nations

Authors: Nuruddeen Usman, Ahmad Muhammad Ibrahim

Abstract:

Management of construction logistics at construction sites becomes increasingly complex with rising construction volume, which made it relatively inefficient in the developing nations even with the technological advancement. The objective of this research is to conceptually synthesise the approaches and challenges befall in the course of construction logistic management, with the aim to proffer possible solution to it. Therefore, this study appraised the glitches associated with both conventional and technological methods of construction logistic management that result in its inefficiency. Thus, this investigation found that, both conventional and the technological issues were due to certain obstacles that affect the construction logistic management which resulted into delays, accidents, fraudulent activities, time and cost overrun. Therefore, this study has developed a framework that might bring a lasting solution to the challenges of construction logistic management.

Keywords: construction, conventional, logistic, technological

Procedia PDF Downloads 554
1406 Dielectric Thickness Modulation Based Optically Transparent Leaky Wave Antenna Design

Authors: Waqar Ali Khan

Abstract:

A leaky-wave antenna design is proposed which is based on the realization of a certain kind of surface impedance profile that allows the existence of a perturbed surface wave (fast wave) that radiates. The antenna is realized by using optically transparent material Plexiglas. Plexiglas behaves as a dielectric at radio frequencies and is transparent at optical frequencies. In order to have a ground plane for the microwave frequencies, metal strips are used parallel to the E field of the operating mode. The microwave wavelength chosen is large enough such that it does not resolve the metal strip ground plane and sees it to be a uniform ground plane. While, at optical frequencies, the metal strips do have some shadowing effect. However still, about 62% of optical power can be transmitted through the antenna.

Keywords: Plexiglass, surface-wave, optically transparent, metal strip

Procedia PDF Downloads 144
1405 An Algorithm for Removal of Noise from X-Ray Images

Authors: Sajidullah Khan, Najeeb Ullah, Wang Yin Chai, Chai Soo See

Abstract:

In this paper, we propose an approach to remove impulse and Poisson noise from X-ray images. Many filters have been used for impulse noise removal from color and gray scale images with their own strengths and weaknesses but X-ray images contain Poisson noise and unfortunately there is no intelligent filter which can detect impulse and Poisson noise from X-ray images. Our proposed filter uses the upgraded layer discrimination approach to detect both Impulse and Poisson noise corrupted pixels in X-ray images and then restores only those detected pixels with a simple efficient and reliable one line equation. Our Proposed algorithms are very effective and much more efficient than all existing filters used only for Impulse noise removal. The proposed method uses a new powerful and efficient noise detection method to determine whether the pixel under observation is corrupted or noise free. Results from computer simulations are used to demonstrate pleasing performance of our proposed method.

Keywords: X-ray image de-noising, impulse noise, poisson noise, PRWF

Procedia PDF Downloads 383
1404 The Comparison of the Effect of the Russian Company’s Female and Male Employees’ Self-Efficacy on the Career Success in Their Professional Activity

Authors: Julia Yalalova, Dilawar Khan Durrani

Abstract:

Subjective and objective career success is one of the vital aims that the employees of any organization want to achieve. However, career success is affected by numerous factors. This study aims to identify few of such key factors that affect career success of individual employees. To achieve this objective, this study aims at empirically analyzing that weather or not self-efficacy of employees impacts their career success. Furthermore, this study also aims to analyze whether or not work effort mediates the relationship between self-efficacy and career success. The study will also test weather emotional intelligence moderate the relationship between self-efficacy and work effort. Furthermore, gender based differences related to all the variables are also the focus of this study. The data will be analyzed using SPSS software and the results, recommendations and future implications will be discussed.

Keywords: career success, emotional intelligence, self-efficacy, work effort

Procedia PDF Downloads 287
1403 Integrated Location-Allocation Planning in Multi Product Multi Echelon Single Period Closed Loop Supply Chain Network Design

Authors: Santhosh Srinivasan, Vipul Garhiya, Shahul Hamid Khan

Abstract:

Environmental performance along with social performance is becoming vital factors for industries to achieve global standards. With a good environmental policy global industries are differentiating them from their competitors. This paper concentrates on multi stage, multi product and multi period manufacturing network. Single objective mathematical models for a total cost for the entire forward supply chain and reverse chain are considered. Here five different problems are considered by varying the number of facilities for illustration. M-MOGA, Shuffle Frog Leaping algorithm (SFLA) and CPLEX are used for finding the optimal solution for the mathematical model.

Keywords: closed loop supply chain, genetic algorithm, random search, multi period, green supply chain

Procedia PDF Downloads 391
1402 Bleaching Liquor Recovery of Batch-Wise and Continuous Method

Authors: Sidra Saleemi, Arsalan Khan, Urooj Baig, Tahir Jamil

Abstract:

In this research, it was examined that some residual amount of bleaching chemicals left in the liquor, this amount is more in Batch-wise process as compared to continuous process. These chemicals can be recovered and reused for bleaching by adding more quantity of fresh bleaching chemicals and water, this quantity will be required to balance the recipe for fabric. This liquor is recovered and samples were bleached with different modified recipe of liquor for both processes i.e. Batch-wise and continuous process. Every time good results were achieved with negligible variation in the quality parameter between the fabric bleached with fresh liquor and the fabric bleached with Recovered Liquor. Additionally, samples were dyed, and found that dyeing can be done easily on samples bleached with recover liquor.

Keywords: bleaching process, hydrogen peroxide, sodium hydroxide, liquor recovery

Procedia PDF Downloads 363
1401 Simulation versus Hands-On Learning Methodologies: A Comparative Study for Engineering and Technology Curricula

Authors: Mohammed T. Taher, Usman Ghani, Ahmed S. Khan

Abstract:

This paper compares the findings of two studies conducted to determine the effectiveness of simulation-based, hands-on and feedback mechanism on students learning by answering the following questions: 1). Does the use of simulation improve students’ learning outcomes? 2). How do students perceive the instructional design features embedded in the simulation program such as exploration and scaffolding support in learning new concepts? 3.) What is the effect of feedback mechanisms on students’ learning in the use of simulation-based labs? The paper also discusses the other aspects of findings which reveal that simulation by itself is not very effective in promoting student learning. Simulation becomes effective when it is followed by hands-on activity and feedback mechanisms. Furthermore, the paper presents recommendations for improving student learning through the use of simulation-based, hands-on, and feedback-based teaching methodologies.

Keywords: simulation-based teaching, hands-on learning, feedback-based learning, scaffolding

Procedia PDF Downloads 462
1400 Heart Failure Identification and Progression by Classifying Cardiac Patients

Authors: Muhammad Saqlain, Nazar Abbas Saqib, Muazzam A. Khan

Abstract:

Heart Failure (HF) has become the major health problem in our society. The prevalence of HF has increased as the patient’s ages and it is the major cause of the high mortality rate in adults. A successful identification and progression of HF can be helpful to reduce the individual and social burden from this syndrome. In this study, we use a real data set of cardiac patients to propose a classification model for the identification and progression of HF. The data set has divided into three age groups, namely young, adult, and old and then each age group have further classified into four classes according to patient’s current physical condition. Contemporary Data Mining classification algorithms have been applied to each individual class of every age group to identify the HF. Decision Tree (DT) gives the highest accuracy of 90% and outperform all other algorithms. Our model accurately diagnoses different stages of HF for each age group and it can be very useful for the early prediction of HF.

Keywords: decision tree, heart failure, data mining, classification model

Procedia PDF Downloads 402
1399 Analytical Solutions of Time Space Fractional, Advection-Dispersion and Whitham-Broer-Kaup Equations

Authors: Muhammad Danish Khan, Imran Naeem, Mudassar Imran

Abstract:

In this article, we study time-space Fractional Advection-Dispersion (FADE) equation and time-space Fractional Whitham-Broer-Kaup (FWBK) equation that have a significant role in hydrology. We introduce suitable transformations to convert fractional order derivatives to integer order derivatives and as a result these equations transform into Partial Differential Equations (PDEs). Then the Lie symmetries and corresponding optimal systems of the resulting PDEs are derived. The symmetry reductions and exact independent solutions based on optimal system are investigated which constitute the exact solutions of original fractional differential equations.

Keywords: modified Riemann-Liouville fractional derivative, lie-symmetries, optimal system, invariant solutions

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1398 Quality Education for the Poor People: Strategy of Islamic Education in the Medium Community

Authors: Naufal Ahmad Rijalul Alam

Abstract:

This article presents a quality of education for the poor people in Indonesia and the offering of strategy to be done. It also investigates the influence of Islamic Education which stands behind the religious values in developing effort of government to respond the problem with using humanities approaches in medium society. The offering strategy resulted in four agenda: 1) building a shared commitment, 2) encouraging the improvement of the quality of public and private schools, 3) encouraging the use of 'the indicator of disaffection' for gifted children, and 4) encouraging the enlargement of vocational training centers and polytechnics. The conclusion is that the quality of education can be increased with these four agenda, although they are not too easy because it deals with other factors such as the economy, politics, and culture which is happening in the country.

Keywords: quality education, poor people, strategy of Islamic education, medium community

Procedia PDF Downloads 480
1397 Biodiversity of Aphid Species (Homoptera: Aphididae) in Hyderabad District, Sindh, Pakistan

Authors: Mahpara Pirzada, Mansoor Ali Shah, Saima Pthan, Kamal Khan, Faiza

Abstract:

Present study based on biodiversity of aphid in different crops of Hyderabad district and its, surrounding area to observe the biodiversity of aphids, host plant range of the aphids in Hyderabad and their population also infestation and yield loss aphid on different crops. We have surveyed different fields of Hyderabad, Jamshoro, and collected the aphids from various parts of plants, grasses, and herb with the help of camel brush. They have been brought to the laboratory into plastic jars and preserved in Glycerin (Glycerol). As a result, 383 individuals belonging to 3 species were identified. These identified species were Aphis fabae, Myzus persicae, and Brevicoryne brassicae. Out of the 3 habitats the maximum richness, evenness, and diversity were recorded in agriculture crops followed by flowering vegetables and minimum in fodder crops. The most abundant specie is Myzus persicae.

Keywords: aphid species, biodiversity, Homoptera:Aphididae, Pakistan

Procedia PDF Downloads 328
1396 Safety Factors for Improvement of Labor's Health and Safety in Construction Industry of Pakistan

Authors: Ahsan Ali Khan

Abstract:

During past few years, researchers are emphasizing more on the need of safety in construction industry. This need of safety is an important issue in developing countries. As due to development they are facing huge construction growth. This research is done to evaluate labor safety condition in construction industry of Pakistan. The research carried out through questionnaire survey at different construction sites. Useful data are gathered from these sites which then factor analyzed resulting in five factors. These factors reflect that most of the workers are aware of the safety need, but they divert this responsibility towards management and claim that the work is more essential for management instead of safety. Moreover, those work force which is unaware of safety state that there is lack of any training and guidance from upper management which lead to many unfavorable events on construction sites. There is need of implementation safety activities by management like training, formulation of rules and policies. This research will be helpful to divert management attention towards safety need so they will make efforts for safety of their manpower—the workers.

Keywords: labor's safety, management role, Pakistan, safety factors

Procedia PDF Downloads 191
1395 Recent Legal Changes in Turkish Commercial Law to Be a Part of International Markets and Their Results

Authors: Ibrahim Arslan

Abstract:

Since 1984, Turkey has experienced a significant transformation in legal and economic matters. The most consequential examples of this transformation in recent years are the renewal of the Commercial Code and the Check Act. Nowadays, the commercial activity is not limited within the boundaries of the country; on the contrary, as required by the global economy, it has an international dimension. For this reason, unlike some other legal principles, the rules regulating the commercial life should be compatible with the international standards as much as possible. Otherwise the development possibility in the global markets will be limited. The Check Act has been adopted in 2009 and the Commercial Code has been adopted in 2011. The Commercial Code has been entered into force on 1 July 2012. The international dimension of check is in-disputable for it is based on the Geneva Convention. However, the Turkish business life has created a unique application of this legal tool. This application is called “post-date” checks. Indeed the majority of the checks being used in the market are post-dated checks. The holders of these checks have waited the date written on the check for presentation and collection. Thus, the actual situation has occurred. This actual situation has been legitimized via Check Act No. 5941 and post dated checks have gained a legal status. In the preparation of the new the Turkish Commercial Code one of the goals is "to ensure that the Turkish commercial law becomes a part of the international market". To achieve this goal, significant changes have been made especially concerning the independent external audition of the corporations, the board structure and public disclosure regulations. These changes aim to facilitate the internationalization of Turkish corporations as well as intensification of foreign direct investments through foreign capital. Although the target has been determined this way, after the adoption but five days before the entry into force of the Turkish Commercial Code No. 6102, a law made backward going alterations concerning independent external audition and public disclosure regulations. Turkish Commercial Code has been currently in force with its altered status. Both the regulations in the Check Act as well as the changes in the Commercial Code are not compatible with the goals introduced by rationale “to ensure Turkish commercial law to be a part of the international market” as such.

Keywords: Turkish Commercial Code No. 6102, Turkish Check Act, “post-date” checks, legal changes

Procedia PDF Downloads 294
1394 Fractal Behaviour of Earthquake Sequences in Himalaya

Authors: Kamal, Adil Ahmad

Abstract:

Earthquakes are among the most versatile natural and dynamic processes, and hence a fractal model is considered to be the best representative of the same. We present a novel method to process and analyse information hidden in earthquake sequences using Fractal Dimensions and Iterative Function Systems (IFS). Spatial and temporal variations in the fractal dimensions of seismicity observed around the Indian peninsula in last 30 years are studied. This was used as a possible precursor before large earthquakes in the region. IFS images for observed seismicity in the Himalayan belt were also obtained. We scan the whole data set and coarse grain of a selected window to reduce it to four bins. A critical analysis of four-cornered chaos-game clearly shows that the spatial variation in earthquake occurrences in Himalayan range is not random. Two subzones of Himalaya have a tendency to follow each other in time.

Keywords: earthquakes, fractals, Himalaya, iterated function systems

Procedia PDF Downloads 300
1393 Performance Evaluation of Distributed and Co-Located MIMO LTE Physical Layer Using Wireless Open-Access Research Platform

Authors: Ishak Suleiman, Ahmad Kamsani Samingan, Yeoh Chun Yeow, Abdul Aziz Bin Abdul Rahman

Abstract:

In this paper, we evaluate the benefits of distributed 4x4 MIMO LTE downlink systems compared to that of the co-located 4x4 MIMO LTE downlink system. The performance evaluation was carried out experimentally by using Wireless Open-Access Research Platform (WARP), where the comparison between the 4x4 MIMO LTE transmission downlink system in distributed and co-located techniques was examined. The measured Error Vector Magnitude (EVM) results showed that the distributed technique achieved better system performance compared to the co-located arrangement.

Keywords: multiple-input-multiple-output (MIMO), distributed MIMO, co-located MIMO, LTE

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1392 A Three-Step Iterative Process for Common Fixed Points of Three Contractive-Like Operators

Authors: Safeer Hussain Khan, H. Fukhar-ud-Din

Abstract:

The concept of quasi-contractive type operators was given by Berinde and extended by Imoru and Olatinwo. They named this new type as contractive-like operators. On the other hand, Xu and Noo introduced a three-step-one-mappings iterative process which can be seen as a generalization of Mann and Ishikawa iterative processes. Approximating common fixed points has its own importance as it has a direct link with minimization problem. Motivated by this, in this paper, we first extend the iterative process of Xu and Noor to the case of three-step-three-mappings and then prove a strong convergence result using contractive-like operators for this iterative process. In general, this generalizes corresponding results using Mann, Ishikawa and Xu-Noor iterative processes with quasi-contractive type operators. It is to be pointed out that our results can also be proved with iterative process involving error terms.

Keywords: contractive-like operator, iterative process, common fixed point, strong convergence

Procedia PDF Downloads 594
1391 Transverse Testicular Ectopia: A Case Report with Review of Literature

Authors: Rida Ahmad, Areej S. Habib, Sohail A. Dogar, Saqib H. Qazi

Abstract:

Transverse testicular ectopia is a rare congenital disorder involving mal descent and mal-positioning of the testes, reported in the medical literature about 300 times. Many theories attempt to explain the failure of the testes to migrate to their correct location. While the age at presentation can vary; most cases present in early adolescents or late adulthood. It is often an incidental discovery made during an operative intervention, most commonly during hernia exploration. It can be isolated or present with a plethora of anomalies. We present the case of a 2-year-old male with transverse testicular ectopia who presented with vague abdominal pain. He was managed successfully with the Modified Ombredanne procedure and good outcome 6 months after the procedure.

Keywords: cryptorchidism, persistent Mullerian duct syndrome, transverse testicular ectopia, testicular mal-descent

Procedia PDF Downloads 341
1390 Design an Expert System to Assess the Hydraulic System in Thermal and Hydrodynamic Aspect

Authors: Ahmad Abdul-Razzak Aboudi Al-Issa

Abstract:

Thermal and Hydrodynamic are basic aspects in any hydraulic system and therefore, they must be assessed with regard to this aspect before constructing the system. This assessment needs a good expertise in this aspect to obtain an efficient hydraulic system. Therefore, this study aims to build an expert system called Hydraulic System Calculations (HSC) to ensure a smooth operation for the hydraulic system. The expert system (HSC) had been designed and coded in an user-friendly interactive program called Microsoft Visual Basic 2010. The suggested code provides the designer with a number of choices to resolve the problem of hydraulic oil overheating which may arise during the continuous operation of the hydraulic unit. As a result, the HSC can minimize the human errors, effort, time and cost of hydraulic machine design.

Keywords: fluid power, hydraulic system, thermal and hydrodynamic, expert system

Procedia PDF Downloads 446
1389 Adult and Non Formal Education for the Attainment of Enterprenuerial Skills in Nigeria

Authors: Zulaiha Maluma Ahmad

Abstract:

This paper attempted to examine adult and non formal education for the attainment of entrepreneurial skills in empowering the citizens with entrepreneurial skills, for Nigeria’s socioeconomic development. This paper highlighted the meaning of education in the context of skill acquisition, entrepreneurial education, adult and non formal education. It also examined the objectives, issues and challenges as well as prospects of this type of education. It further discussed the role of adult and non formal education for the attainment of socioeconomic development of a growing nation like Nigeria. The paper equally proffered some recommendations and eventually concluded that adult and non formal education can indeed make self reliance, personal satisfaction and the attainment of entrepreneurial education for the socioeconomic development of any nation, possible.

Keywords: entrepreneurial education, adult education, non formal education skills, Nigeria

Procedia PDF Downloads 597
1388 Study of Tribological Behaviour of Al6061/Silicon Carbide/Graphite Hybrid Metal Matrix Composite Using Taguchi's Techniques

Authors: Mohamed Zakaulla, A. R. Anwar Khan

Abstract:

Al6061 alloy base matrix, reinforced with particles of silicon carbide (10 wt %) and Graphite powder (1wt%), known as hybrid composites have been fabricated by liquid metallurgy route (stir casting technique) and optimized at different parameters like applied load, sliding speed and sliding distance by taguchi method. A plan of experiment generated through taguchi technique was used to perform experiments based on L27 orthogonal array. The developed ANOVA and regression equations are used to find the optimum coefficient of friction and wear under the influence of applied load, sliding speed and sliding distance. On the basis of “smaller the best” the dry sliding wear resistance was analysed and finally confirmation tests were carried out to verify the experimental results.

Keywords: analysis of variance, dry sliding wear, hybrid composite, orthogonal array, Taguchi technique

Procedia PDF Downloads 467
1387 Why Trust Matters for Women Entrepreneurs: Insights from Malaysia

Authors: Suraini Mohd Rhouse, Noor Lela Ahmad, Nek Kamal Yeop Yunus, Rosfizah Md Taib

Abstract:

This article aims to explore the importance of trust to women entrepreneurs. In particular, the research uses a social constructionist lens to examine ways in which women entrepreneurs construct trust in relation to their various stakeholders. A semi-structured interview was used to gather the data. The findings suggest women highlight the importance of trust in order to establish customer satisfaction that can further develop customer loyalty. In addition, aspect of trust with the employees is seen as vital for building organizational commitment to the business organization. Women also see the trust dimension in terms of their relationships with financial providers in order to gain approval for financial resources. This article contributes to the literature on the value of trust to women’s business environments.

Keywords: qualitative, social constructionist, trust, women entrepreneurship

Procedia PDF Downloads 560
1386 Optimized Approach for Secure Data Sharing in Distributed Database

Authors: Ahmed Mateen, Zhu Qingsheng, Ahmad Bilal

Abstract:

In the current age of technology, information is the most precious asset of a company. Today, companies have a large amount of data. As the data become larger, access to data for some particular information is becoming slower day by day. Faster data processing to shape it in the form of information is the biggest issue. The major problems in distributed databases are the efficiency of data distribution and response time of data distribution. The security of data distribution is also a big issue. For these problems, we proposed a strategy that can maximize the efficiency of data distribution and also increase its response time. This technique gives better results for secure data distribution from multiple heterogeneous sources. The newly proposed technique facilitates the companies for secure data sharing efficiently and quickly.

Keywords: ER-schema, electronic record, P2P framework, API, query formulation

Procedia PDF Downloads 333
1385 Effect of Pulse Duration and Current to the EDM Process on Allegheny Ludlum D2 Tool Steel

Authors: S. Sulaiman, M. A. Razak, M. R. Ibrahim, A. A. Khan

Abstract:

An experimental work on the effect of different current and pulse duration on performance of EDM process of Allegheny Ludlum D2 Tool Steel (UNS T30402). The effect of varying the machining parameters on the machining responses such as material removal rate (MRR), electrode wear rate (EWR), and surface roughness (Ra) have been investigated. In this study, triangular shape and circular shape of copper was used as an electrode with surface area of 100 mm². The experiments were repeated for three different values of pulse duration (100 µs, 200 µs and 400 µs) with combination of three different values of discharge current (12 A, 16 A and 24 A). It was found that the pulse duration and current have significant effect on MRR, EWR and Ra. An increase in the pulse durations causes an increase in the MRR and Ra, but a decrease in the EWR. Meanwhile, the effect of currents on EDM performance shows that the increasing currents lead to an increase in the MRR, EWR and Ra.

Keywords: allegheny ludlum D2 tool steel, current, EDM, surface roughness, pulse duration

Procedia PDF Downloads 379
1384 Topic Sentiments toward the COVID-19 Vaccine on Twitter

Authors: Melissa Vang, Raheyma Khan, Haihua Chen

Abstract:

The coronavirus disease 2019 (COVID‐19) pandemic has changed people's lives from all over the world. More people have turned to Twitter to engage online and discuss the COVID-19 vaccine. This study aims to present a text mining approach to identify people's attitudes towards the COVID-19 vaccine on Twitter. To achieve this purpose, we collected 54,268 COVID-19 vaccine tweets from September 01, 2020, to November 01, 2020, then the BERT model is used for the sentiment and topic analysis. The results show that people had more negative than positive attitudes about the vaccine, and countries with an increasing number of confirmed cases had a higher percentage of negative attitudes. Additionally, the topics discussed in positive and negative tweets are different. The tweet datasets can be helpful to information professionals to inform the public about vaccine-related informational resources. Our findings may have implications for understanding people's cognitions and feelings about the vaccine.

Keywords: BERT, COVID-19 vaccine, sentiment analysis, topic modeling

Procedia PDF Downloads 150
1383 Tongue Image Retrieval Based Using Machine Learning

Authors: Ahmad FAROOQ, Xinfeng Zhang, Fahad Sabah, Raheem Sarwar

Abstract:

In Traditional Chinese Medicine, tongue diagnosis is a vital inspection tool (TCM). In this study, we explore the potential of machine learning in tongue diagnosis. It begins with the cataloguing of the various classifications and characteristics of the human tongue. We infer 24 kinds of tongues from the material and coating of the tongue, and we identify 21 attributes of the tongue. The next step is to apply machine learning methods to the tongue dataset. We use the Weka machine learning platform to conduct the experiment for performance analysis. The 457 instances of the tongue dataset are used to test the performance of five different machine learning methods, including SVM, Random Forests, Decision Trees, and Naive Bayes. Based on accuracy and Area under the ROC Curve, the Support Vector Machine algorithm was shown to be the most effective for tongue diagnosis (AUC).

Keywords: medical imaging, image retrieval, machine learning, tongue

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1382 Scenario of Some Minerals and Impact of Promoter Hypermethylation of DAP-K Gene in Gastric Carcinoma Patients of Kashmir Valley

Authors: Showkat Ahmad Bhat, Iqra Reyaz, Falaque ul Afshan, Ahmad Arif Reshi, Muneeb U. Rehman, Manzoor R. Mir, Sabhiya Majid, Sonallah, Sheikh Bilal, Ishraq Hussain

Abstract:

Background: Gastric cancer is the fourth most common cancer and the second leading cause of worldwide cancer-related deaths, with a wide variation in incidence rates across different geographical areas. The current view of cancer is that a malignancy arises from a transformation of the genetic material of a normal cell, followed by successive mutations and by chain of alterations in genes such as DNA repair genes, oncogenes, Tumor suppressor genes. Minerals are necessary for the functioning of several transcriptional factors, proteins that recognize certain DNA sequences and have been found to play a role in gastric cancer. Material Methods:The present work was a case control study and its aim was to ascertain the role of minerals and promoter hypermethylation of CpG islands of DAP-K gene in Gastric cancer patients among the Kashmiri population. Serum was extracted from all the samples and mineral estimation was done by AAS from serum, DNA was also extracted and was modified using bisulphite modification kit. Methylation-specific PCR was used for the analysis of the promoter hypermethylation status of DAP-K gene. The epigenetic analysis revealed that unlike other high risk regions, Kashmiri population has a different promoter hypermethylation profile of DAP-K gene and has different mineral profile. Results: In our study mean serum copper levels were significantly different for the two genders (p<0.05), while as no significant differences were observed for iron and zinc levels. In Methylation-specific PCR the methylation status of the promoter region of DAP-K gene was as 67.50% (27/40) of the gastric cancer tissues showed methylated DAP-K promoter and 32.50% (13/40) of the cases however showed unmethylated DAP-K promoter. Almost all 85% (17/20) of the histopathologically confirmed normal tissues showed unmethylated DAP-K promoter except only in 3 cases where DAP-K promoter was found to be methylated. The association of promoter hypermethylation with gastric cancer was evaluated by χ2 (Chi square) test and was found to be significant (P=0.0006). Occurrence of DAP-K methylation was found to be unequally distributed in males and females with more frequency in males than in females but the difference was not statistically significant (P =0.7635, Odds ratio=1.368 and 95% C.I=0.4197 to 4.456). When the frequency of DAP-K promoter methylation was compared with clinical staging of the disease, DAP-K promoter methylation was found to be certainly higher in Stage III/IV (85.71%) compared to Stage I/ II (57.69%) but the difference was not statistically significant (P =0.0673). These results suggest that DAP-K aberrant promoter hypermethylation in Kashmiri population contributes to the process of carcinogenesis in Gastric cancer and is reportedly one of the commonest epigenetic changes in the development of Gastric cancer.

Keywords: gastric cancer, minerals, AAS, hypermethylation, CpG islands, DAP-K gene

Procedia PDF Downloads 517
1381 The Application of Lean-Kaizen in Course Plan and Delivery in Malaysian Higher Education Sector

Authors: Nur Aishah Binti Awi, Zulfiqar Khan

Abstract:

Lean-kaizen has always been applied in manufacturing sector since many years ago. What about education sector? This paper discuss on how lean-kaizen can also be applied in education sector, specifically in academic area of Malaysian’s higher education sector. The purpose of this paper is to describe the application of lean kaizen in course plan and delivery. Lean-kaizen techniques have been used to identify waste in the course plan and delivery. A field study has been conducted to obtain the data. This study used both quantitative and qualitative data. The researcher had interviewed the chosen lecturers regarding to the problems of course plan and delivery that they encountered. Secondary data of students’ feedback at the end of semester also has been used to improve course plan and delivery. The result empirically shows that lean-kaizen helps to improve the course plan and delivery by reducing the wastes. Thus, this study demonstrates that lean-kaizen can also help education sector to improve their services as achieved by manufacturing sector.

Keywords: course delivery, education, Kaizen, lean

Procedia PDF Downloads 368
1380 Teaching Prosthetic and Orthotics in Palestine: Between Reality and Challenges

Authors: Ahmad Dawabsheh

Abstract:

The science of prosthetics is a renewable science that serves all humanity, regardless of gender, religion and race, and its causes are many: wars, conflicts, traffic accidents, and others. The researcher believes that there are challenges facing the specialization, including that society views a negative view of the amputee, especially if it is a female. This research aims to focus on the reality of teaching prosthetics in Palestine, especially in the Arab American University, as it is the only major. As well as the challenges facing this major: financial, human, academic, laboratories, and others. The researcher used the descriptive and analytical approach, which is the closest approach to studying the subject. The researcher believes that there is a failure on the part of the state and the Ministry of Health in this matter. In addition to the lack of societal culture, as well as the large quantities of prosthetic fittings.

Keywords: prothetics, orthotics, Arab American University, Palestine

Procedia PDF Downloads 142
1379 How to Perform Proper Indexing?

Authors: Watheq Mansour, Waleed Bin Owais, Mohammad Basheer Kotit, Khaled Khan

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Efficient query processing is one of the utmost requisites in any business environment to satisfy consumer needs. This paper investigates the various types of indexing models, viz. primary, secondary, and multi-level. The investigation is done under the ambit of various types of queries to which each indexing model performs with efficacy. This study also discusses the inherent advantages and disadvantages of each indexing model and how indexing models can be chosen based on a particular environment. This paper also draws parallels between various indexing models and provides recommendations that would help a Database administrator to zero-in on a particular indexing model attributed to the needs and requirements of the production environment. In addition, to satisfy industry and consumer needs attributed to the colossal data generation nowadays, this study has proposed two novel indexing techniques that can be used to index highly unstructured and structured Big Data with efficacy. The study also briefly discusses some best practices that the industry should follow in order to choose an indexing model that is apposite to their prerequisites and requirements.

Keywords: indexing, hashing, latent semantic indexing, B-tree

Procedia PDF Downloads 156
1378 The First Report of Fresh Water Crab Potamon Potamios (Decapoda: brachyura) in Chahnimeh’s Water Reservoirs from Sistan, Iran

Authors: Ahmad Gharaei, Javad Mirdar Harijani

Abstract:

The freshwater crab family (Potamidae Ortmann, 1896) is a big group and varies over 500 species in 74 genuses. This family distributed in South Europe, South Africa, East and South-east Asian. Iran's Sistan region located in the South East and recently after a decade of drought in the international wetland of Hamoon, in fact, the aquatic fauna in the Chahnimeh’s water reservoirs had taken refuge. This paper reports the second site for Potamon Potamios, in the southern half of the Iran. The specimens were collected from the shallow water in reservoir banks with muddy bottom in July 2010. The morphological features, habitat and systematic, are described.

Keywords: freshwater crab, potamon potamios, sistan, Iran

Procedia PDF Downloads 533