Search results for: mathematical algorithm
1686 Database Compression for Intelligent On-board Vehicle Controllers
Authors: Ágoston Winkler, Sándor Juhász, Zoltán Benedek
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The vehicle fleet of public transportation companies is often equipped with intelligent on-board passenger information systems. A frequently used but time and labor-intensive way for keeping the on-board controllers up-to-date is the manual update using different memory cards (e.g. flash cards) or portable computers. This paper describes a compression algorithm that enables data transmission using low bandwidth wireless radio networks (e.g. GPRS) by minimizing the amount of data traffic. In typical cases it reaches a compression rate of an order of magnitude better than that of the general purpose compressors. Compressed data can be easily expanded by the low-performance controllers, too.
Keywords: Data analysis, data compression, differentialencoding, run-length encoding, vehicle control.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 15671685 Towards a Standardization in Scheduling Models: Assessing the Variety of Homonyms
Authors: Marcel Rojahn, Edzard Weber, Norbert Gronau
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Terminology is a critical instrument for each researcher. Different terminologies for the same research object may arise in different research communities. By this inconsistency, many synergistic effects get lost. Theories and models will be more understandable and reusable if a common terminology is applied. This paper examines the terminological (in)consistence for the research field of job-shop scheduling by a literature review. There is an enormous variety in the choice of terms and mathematical notation for the same concept. The comparability, reusability and combinability of scheduling methods is unnecessarily hampered by the arbitrary use of homonyms and synonyms. The acceptance in the community of used variables and notation forms is shown by means of a compliance quotient. This is proven by the evaluation of 240 scientific publications on planning methods.
Keywords: Job-shop scheduling, JSP, terminology, notation, standardization.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3131684 Improvement of Blood Detection Accuracy using Image Processing Techniques suitable for Capsule Endoscopy
Authors: Yong-Gyu Lee, Gilwon Yoon
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Bleeding in the digestive duct is an important diagnostic parameter for patients. Blood in the endoscopic image can be determined by investigating the color tone of blood due to the degree of oxygenation, under- or over- illumination, food debris and secretions, etc. However, we found that how to pre-process raw images obtained from the capsule detectors was very important. We applied various image process methods suitable for the capsule endoscopic image in order to remove noises and unbalanced sensitivities for the image pixels. The results showed that much improvement was achieved by additional pre-processing techniques on the algorithm of determining bleeding areas.
Keywords: blood detection, capsule endoscopy, image processing.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 18921683 Application of Adaptive Neuro-Fuzzy Inference System in Smoothing Transition Autoregressive Models
Authors: Ε. Giovanis
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In this paper we propose and examine an Adaptive Neuro-Fuzzy Inference System (ANFIS) in Smoothing Transition Autoregressive (STAR) modeling. Because STAR models follow fuzzy logic approach, in the non-linear part fuzzy rules can be incorporated or other training or computational methods can be applied as the error backpropagation algorithm instead to nonlinear squares. Furthermore, additional fuzzy membership functions can be examined, beside the logistic and exponential, like the triangle, Gaussian and Generalized Bell functions among others. We examine two macroeconomic variables of US economy, the inflation rate and the 6-monthly treasury bills interest rates.Keywords: Forecasting, Neuro-Fuzzy, Smoothing transition, Time-series
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16301682 Code-Aided Turbo Channel Estimation for OFDM Systems with NB-LDPC Codes
Authors: Ł. Januszkiewicz, G. Bacci, H. Gierszal, M. Luise
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In this paper channel estimation techniques are considered as the support methods for OFDM transmission systems based on Non Binary LDPC (Low Density Parity Check) codes. Standard frequency domain pilot aided LS (Least Squares) and LMMSE (Linear Minimum Mean Square Error) estimators are investigated. Furthermore, an iterative algorithm is proposed as a solution exploiting the NB-LDPC channel decoder to improve the performance of the LMMSE estimator. Simulation results of signals transmitted through fading mobile channels are presented to compare the performance of the proposed channel estimators.Keywords: LDPC codes, LMMSE, OFDM, turbo channelestimation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16591681 Morphological Description of Cervical Cell Images for the Pathological Recognition
Authors: N. Lassouaoui, L. Hamami, N. Nouali
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The tracking allows to detect the tumor affections of cervical cancer, it is particularly complex and consuming time, because it consists in seeking some abnormal cells among a cluster of normal cells. In this paper, we present our proposed computer system for helping the doctors in tracking the cervical cancer. Knowing that the diagnosis of the malignancy is based in the set of atypical morphological details of all cells, herein, we present an unsupervised genetic algorithm for the separation of cell components since the diagnosis is doing by analysis of the core and the cytoplasm. We give also the various algorithms used for computing the morphological characteristics of cells (Ratio core/cytoplasm, cellular deformity, ...) necessary for the recognition of illness.
Keywords: Cervical cell, morphological analysis, recognition, segmentation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19411680 Adaptive Radio Resource Allocation for Multiple Traffic OFDMA Broadband Wireless Access System
Authors: Lu Yanhui, Zhang Lizhi, Yin Changchuan, Yue Guangxin
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In this paper, an adaptive radio resource allocation (RRA) algorithm applying to multiple traffic OFDMA system is proposed, which distributes sub-carrier and loading bits among users according to their different QoS requirements and traffic class. By classifying and prioritizing the users based on their traffic characteristic and ensuring resource for higher priority users, the scheme decreases tremendously the outage probability of the users requiring a real time transmission without impact on the spectrum efficiency of system, as well as the outage probability of data users is not increased compared with the RRA methods published.Keywords: OFDMA, adaptive radio resource allocation, QoS.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16891679 Non-reflection Boundary Conditions for Numerical Simulation of Supersonic Flow
Authors: A. Abdalla, A. Kaltayev
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This article presents the boundary conditions for the problem of turbulent supersonic gas flow in a plane channel with a perpendicular injection jets. The non-reflection boundary conditions for direct modeling of compressible viscous gases are studied. A formulation using the NSCBC (Navier- Stocks characteristic boundary conditions) through boundaries is derived for the subsonic inflow and subsonic non-reflection outflow situations. Verification of the constructed algorithm of boundary conditions is carried out by solving a test problem of perpendicular sound of jets injection into a supersonic gas flow in a plane channel.
Keywords: WENO scheme, non-reflection boundary conditions, NSCBC, supersonic flow.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 21961678 Contour Estimation in Synthetic and Real Weld Defect Images based on Maximum Likelihood
Authors: M. Tridi, N. Nacereddine, N. Oucief
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This paper describes a novel method for automatic estimation of the contours of weld defect in radiography images. Generally, the contour detection is the first operation which we apply in the visual recognition system. Our approach can be described as a region based maximum likelihood formulation of parametric deformable contours. This formulation provides robustness against the poor image quality, and allows simultaneous estimation of the contour parameters together with other parameters of the model. Implementation is performed by a deterministic iterative algorithm with minimal user intervention. Results testify for the very good performance of the approach especially in synthetic weld defect images.Keywords: Contour, gaussian, likelihood, rayleigh.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16611677 Experiments of a Free Surface Flow in a Hydraulic Channel over an Uneven Bottom
Authors: M. Bouinoun, M. Bouhadef
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The present study is concerned with the problem of determining the shape of the free surface flow in a hydraulic channel which has an uneven bottom. For the mathematical formulation of the problem, the fluid of the two-dimensional irrotational steady flow in water is assumed inviscid and incompressible. The solutions of the nonlinear problem are obtained by using the usual conformal mapping theory and Hilbert’s technique. An experimental study, for comparing the obtained results, has been conducted in a hydraulic channel (subcritical regime and supercritical regime).
Keywords: Free-surface flow, experiments, numerical method, uneven bottom, supercritical regime, subcritical regime.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16901676 Numerical Investigation of Instabilities in Free Shear Layer Produced by NS-DBD Actuator
Authors: Ilya Popov, Steven Hulshoff
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A numerical investigation of the effects of nanosecond barrier discharge on the stability of a two-dimensional free shear layer is performed. The computations are carried out using a compressible Navier-Stokes algorithm coupled with a thermodynamic model of the discharge. The results show that significant increases in the shear layer-s momentum thickness and Reynolds stresses occur due to actuation. Dependence on both frequency and amplitude of actuation are considered, and a comparison is made of the computed growth rates with those predicted by linear stability theory. Amplitude and frequency ranges for the efficient promotion of shear-layer instabilities are identified.Keywords: NS-DBD, plasma, actuator, flow control, instability, shear layer
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 17011675 The Possibility of Solving a 3x3 Rubik’s Cube under 3 Seconds
Authors: Chung To Kong, Siu Ming Yiu
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Rubik's cube was invented in 1974. Since then, speedcubers all over the world try their best to break the world record again and again. The newest record is 3.47 seconds. There are many factors that affect the timing including turns per second (tps), algorithm, finger trick, and hardware of the cube. In this paper, the lower bound of the cube solving time will be discussed using convex optimization. Extended analysis of the world records will be used to understand how to improve the timing. With the understanding of each part of the solving step, the paper suggests a list of speed improvement technique. Based on the analysis of the world record, there is a high possibility that the 3 seconds mark will be broken soon.
Keywords: Rubik’s cube, convex optimization, speed cubing, CFOP.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 8451674 An Integrated Mixed-Integer Programming Model to Address Concurrent Project Scheduling and Material Ordering
Authors: Babak H. Tabrizi, Seyed Farid Ghaderi
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Concurrent planning of project scheduling and material ordering can provide more flexibility to the project scheduling problem, as the project execution costs can be enhanced. Hence, the issue has been taken into account in this paper. To do so, a mixed-integer mathematical model is developed which considers the aforementioned flexibility, in addition to the materials quantity discount and space availability restrictions. Moreover, the activities duration has been treated as decision variables. Finally, the efficiency of the proposed model is tested by different instances. Additionally, the influence of the aforementioned parameters is investigated on the model performance.Keywords: Material ordering, project scheduling, quantity discount, space availability.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 23811673 Data Placement in Heterogeneous Storage of Short Videos
Authors: W. Jaipahkdee, C. Srinilta
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The overall service performance of I/O intensive system depends mainly on workload on its storage system. In heterogeneous storage environment where storage elements from different vendors with different capacity and performance are put together, workload should be distributed according to storage capability. This paper addresses data placement issue in short video sharing website. Workload contributed by a video is estimated by the number of views and life time span of existing videos in same category. Experiment was conducted on 42,000 video titles in six weeks. Result showed that the proposed algorithm distributed workload and maintained balance better than round robin and random algorithms.Keywords: data placement, heterogeneous storage system, YouTube, short videos
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 14881672 A Competitive Replica Placement Methodology for Ad Hoc Networks
Authors: Samee Ullah Khan, C. Ardil
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In this paper, a mathematical model for data object replication in ad hoc networks is formulated. The derived model is general, flexible and adaptable to cater for various applications in ad hoc networks. We propose a game theoretical technique in which players (mobile hosts) continuously compete in a non-cooperative environment to improve data accessibility by replicating data objects. The technique incorporates the access frequency from mobile hosts to each data object, the status of the network connectivity, and communication costs. The proposed technique is extensively evaluated against four well-known ad hoc network replica allocation methods. The experimental results reveal that the proposed approach outperforms the four techniques in both the execution time and solution qualityKeywords: Data replication, auctions, static allocation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 14021671 Robust Control of a Dynamic Model of an F-16 Aircraft with Improved Damping through Linear Matrix Inequalities
Authors: J. P. P. Andrade, V. A. F. Campos
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This work presents an application of Linear Matrix Inequalities (LMI) for the robust control of an F-16 aircraft through an algorithm ensuring the damping factor to the closed loop system. The results show that the zero and gain settings are sufficient to ensure robust performance and stability with respect to various operating points. The technique used is the pole placement, which aims to put the system in closed loop poles in a specific region of the complex plane. Test results using a dynamic model of the F-16 aircraft are presented and discussed.Keywords: F-16 Aircraft, linear matrix inequalities, pole placement, robust control.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16311670 Motion Planning and Control of Autonomous Robots in a Two-dimensional Plane
Authors: Avinesh Prasad, Bibhya Sharma, Jito Vanualailai
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This paper proposes a solution to the motion planning and control problem of a point-mass robot which is required to move safely to a designated target in a priori known workspace cluttered with fixed elliptical obstacles of arbitrary position and sizes. A tailored and unique algorithm for target convergence and obstacle avoidance is proposed that will work for any number of fixed obstacles. The control laws proposed in this paper also ensures that the equilibrium point of the given system is asymptotically stable. Computer simulations with the proposed technique and applications to a planar (RP) manipulator will be presented.Keywords: Point-mass Robot, Asymptotic stability, Motionplanning, Planar Robot Arm.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16691669 Evaluation of Optimal Residence Time in a Hot Rolled Reheating Furnace
Authors: Dong-Eun Lee
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To calculate the temperature distribution of the slab in a hot rolled reheating furnace a mathematical model has been developed by considering the thermal radiation in the furnace and transient conduction in the slab. The furnace is modeled as radiating medium with spatially varying temperature. Radiative heat flux within the furnace including the effect of furnace walls, combustion gases, skid beams and buttons is calculated using the FVM and is applied as the boundary condition of the transient conduction equation of the slab. After determining the slab emissivity by comparison between simulation and experimental work, variation of heating characteristics in the slab is investigated in the case of changing furnace temperature with various time and the slab residence time is optimized with this evaluation.Keywords: Reheating Furnace, Thermal Radiation, ResidenceTime, FVM for Radiation
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 24971668 Zero-knowledge-like Proof of Cryptanalysis of Bluetooth Encryption
Authors: Eric Filiol
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This paper presents a protocol aiming at proving that an encryption system contains structural weaknesses without disclosing any information on those weaknesses. A verifier can check in a polynomial time that a given property of the cipher system output has been effectively realized. This property has been chosen by the prover in such a way that it cannot been achieved by known attacks or exhaustive search but only if the prover indeed knows some undisclosed weaknesses that may effectively endanger the cryptosystem security. This protocol has been denoted zero-knowledge-like proof of cryptanalysis. In this paper, we apply this protocol to the Bluetooth core encryption algorithm E0, used in many mobile environments and thus we suggest that its security can seriously be put into question.
Keywords: Bluetooth encryption, Bluetooth security, Bluetoothprotocol, Stream cipher, Zero-knowledge, Cryptanalysis
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 15691667 A Mini Radar System for Low Altitude Targets Detection
Authors: Kangkang Wu, Kaizhi Wang, Zhijun Yuan
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This paper deals with a mini radar system aimed at detecting small targets at the low latitude. The radar operates at Ku-band in the frequency modulated continuous wave (FMCW) mode with two receiving channels. The radar system has the characteristics of compactness, mobility, and low power consumption. This paper focuses on the implementation of the radar system, and the Block least mean square (Block LMS) algorithm is applied to minimize the fortuitous distortion. It is validated from a series of experiments that the track of the unmanned aerial vehicle (UAV) can be easily distinguished with the radar system.
Keywords: Unmanned aerial vehicle, interference, block least mean square, frequency modulated continuous wave.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 10961666 Prediction of Post Underwater Shock Properties of Polymer - Clay/Silica Hybrid Nanocomposites through Regression Models
Authors: D. Lingaraju, K. Ramji, M. Pramiladevi, U. Rajyalakshmi
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Exploding concentrated underwater charges to damage underwater structures such as ship hulls is a part of naval warfare strategies. Adding small amounts of foreign particles (like clay or silica) of nanosize significantly improves the engineering properties of the polymers. In the present work the clay in terms 1, 2 and 3 percent by weight was surface treated with a suitable silane agent. The hybrid nanocomposite was prepared by the hand lay-up technique. Mathematical regression models have been employed for theoretical prediction. This will result in considerable savings in terms of project time, effort and cost.Keywords: ANOVA, clay, halloysite, nanocomposites, underwater shock, regression, silica.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 21891665 Quality of Service Evaluation using a Combination of Fuzzy C-Means and Regression Model
Authors: Aboagela Dogman, Reza Saatchi, Samir Al-Khayatt
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In this study, a network quality of service (QoS) evaluation system was proposed. The system used a combination of fuzzy C-means (FCM) and regression model to analyse and assess the QoS in a simulated network. Network QoS parameters of multimedia applications were intelligently analysed by FCM clustering algorithm. The QoS parameters for each FCM cluster centre were then inputted to a regression model in order to quantify the overall QoS. The proposed QoS evaluation system provided valuable information about the network-s QoS patterns and based on this information, the overall network-s QoS was effectively quantified.Keywords: Fuzzy C-means; regression model, network quality of service
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 17201664 Solving the Flexible Job Shop Scheduling Problem with Uniform Processing Time Uncertainty
Authors: Nasr Al-Hinai, Tarek Y. ElMekkawy
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The performance of schedules released to a shop floor may greatly be affected by unexpected disruptions. Thus, this paper considers the flexible job shop scheduling problem when processing times of some operations are represented by a uniform distribution with given lower and upper bounds. The objective is to find a predictive schedule that can deal with this uncertainty. The paper compares two genetic approaches to obtain predictive schedule. To determine the performance of the predictive schedules obtained by both approaches, an experimental study is conducted on a number of benchmark problems.
Keywords: Genetic algorithm, met-heuristic, robust scheduling, uncertainty of processing times
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 28741663 Voltage Stability Proximity Index Determined by LES Algorithm
Authors: Benalia Nadia, Bensiali Nadia, Mekki Mounira
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In this paper, we propose an easily computable proximity index for predicting voltage collapse of a load bus using only measured values of the bus voltage and power; Using these measurements a polynomial of fourth order is obtained by using LES estimation algorithms. The sum of the absolute values of the polynomial coefficient gives an idea of the critical bus. We demonstrate the applicability of our proposed method on 6 bus test system. The results obtained verify its applicability, as well as its accuracy and the simplicity. From this indicator, it is allowed to predict the voltage instability or the proximity of a collapse. Results obtained by the PV curve are compared with corresponding values by QV curves and are observed to be in close agreement.
Keywords: least square method, Voltage Collapse, Voltage Stability, PV curve
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 22841662 Development of a Speed Sensorless IM Drives
Authors: Dj. Cherifi, Y. Miloud, A. Tahri
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The primary objective of this paper is to elimination of the problem of sensitivity to parameter variation of induction motor drive. The proposed sensorless strategy is based on an algorithm permitting a better simultaneous estimation of the rotor speed and the stator resistance including an adaptive mechanism based on the lyaponov theory. To study the reliability and the robustness of the sensorless technique to abnormal operations, some simulation tests have been performed under several cases.
The proposed sensorless vector control scheme showed a good performance behavior in the transient and steady states, with an excellent disturbance rejection of the load torque.
Keywords: Induction Motor Drive, field-oriented control, adaptive speed observer, stator resistance estimation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20271661 Modeling of the Process Parameters using Soft Computing Techniques
Authors: Miodrag T. Manić, Dejan I. Tanikić, Miloš S. Stojković, Dalibor M. ðenadić
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The design of technological procedures for manufacturing certain products demands the definition and optimization of technological process parameters. Their determination depends on the model of the process itself and its complexity. Certain processes do not have an adequate mathematical model, thus they are modeled using heuristic methods. First part of this paper presents a state of the art of using soft computing techniques in manufacturing processes from the perspective of applicability in modern CAx systems. Methods of artificial intelligence which can be used for this purpose are analyzed. The second part of this paper shows some of the developed models of certain processes, as well as their applicability in the actual calculation of parameters of some technological processes within the design system from the viewpoint of productivity.Keywords: fuzzy logic, manufacturing, neural networks
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19101660 Fuzzy Based Visual Texture Feature for Psoriasis Image Analysis
Authors: G. Murugeswari, A. Suruliandi
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This paper proposes a rotational invariant texture feature based on the roughness property of the image for psoriasis image analysis. In this work, we have applied this feature for image classification and segmentation. The fuzzy concept is employed to overcome the imprecision of roughness. Since the psoriasis lesion is modeled by a rough surface, the feature is extended for calculating the Psoriasis Area Severity Index value. For classification and segmentation, the Nearest Neighbor algorithm is applied. We have obtained promising results for identifying affected lesions by using the roughness index and severity level estimation.
Keywords: Fuzzy texture feature, psoriasis, roughness feature, skin disease.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 21161659 Defect Cause Modeling with Decision Tree and Regression Analysis
Authors: B. Bakır, İ. Batmaz, F. A. Güntürkün, İ. A. İpekçi, G. Köksal, N. E. Özdemirel
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The main aim of this study is to identify the most influential variables that cause defects on the items produced by a casting company located in Turkey. To this end, one of the items produced by the company with high defective percentage rates is selected. Two approaches-the regression analysis and decision treesare used to model the relationship between process parameters and defect types. Although logistic regression models failed, decision tree model gives meaningful results. Based on these results, it can be claimed that the decision tree approach is a promising technique for determining the most important process variables.Keywords: Casting industry, decision tree algorithm C5.0, logistic regression, quality improvement.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 25201658 Asynchronous Sequential Machines with Fault Detectors
Authors: Seong Woo Kwak, Jung-Min Yang
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A strategy of fault diagnosis and tolerance for asynchronous sequential machines is discussed in this paper. With no synchronizing clock, it is difficult to diagnose an occurrence of permanent or stuck-in faults in the operation of asynchronous machines. In this paper, we present a fault detector comprised of a timer and a set of static functions to determine the occurrence of faults. In order to realize immediate fault tolerance, corrective control theory is applied to designing a dynamic feedback controller. Existence conditions for an appropriate controller and its construction algorithm are presented in terms of reachability of the machine and the feature of fault occurrences.Keywords: Asynchronous sequential machines, corrective control, fault diagnosis and tolerance, fault detector.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 13651657 Weighted k-Nearest-Neighbor Techniques for High Throughput Screening Data
Authors: Kozak K, M. Kozak, K. Stapor
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The k-nearest neighbors (knn) is a simple but effective method of classification. In this paper we present an extended version of this technique for chemical compounds used in High Throughput Screening, where the distances of the nearest neighbors can be taken into account. Our algorithm uses kernel weight functions as guidance for the process of defining activity in screening data. Proposed kernel weight function aims to combine properties of graphical structure and molecule descriptors of screening compounds. We apply the modified knn method on several experimental data from biological screens. The experimental results confirm the effectiveness of the proposed method.
Keywords: biological screening, kernel methods, KNN, QSAR
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