Search results for: finned tube heat exchangers.

Authors: Sanjay Baburao Kulkarni

Abstract:

Exact solution of an unsteady flow of elastico-viscous fluid through a porous media in a tube of spherical cross section under the influence of constant pressure gradient has been obtained in this paper. Initially, the flow is generated by a constant pressure gradient. After attaining the steady state, the pressure gradient is suddenly withdrawn and the resulting fluid motion in a tube of spherical cross section by taking into account of the porosity factor of the bounding surface is investigated. The problem is solved in twostages the first stage is a steady motion in tube under the influence of a constant pressure gradient, the second stage concern with an unsteady motion. The problem is solved employing separation of variables technique. The results are expressed in terms of a nondimensional porosity parameter (K) and elastico-viscosity parameter (β), which depends on the Non-Newtonian coefficient. The flow parameters are found to be identical with that of Newtonian case as elastic-viscosity parameter tends to zero and porosity tends to infinity. It is seen that the effect of elastico-viscosity parameter, porosity parameter of the bounding surface has significant effect on the velocity parameter.

Keywords: Elastico-viscous fluid, Porous media, Second order fluids, Spherical cross-section.

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Authors: Chul Ho Han, Kyoung Hoon Kim

Abstract:

This paper carries out a performance analysis based on the first and second laws of thermodynamics for heat recovery vapor generator (HRVG) of ammonia-water mixture when the heat source is low-temperature energy in the form of sensible heat. In the analysis, effects of the ammonia mass concentration and mass flow ratio of the binary mixture are investigated on the system performance including the effectiveness of heat transfer, entropy generation, and exergy efficiency. The results show that the ammonia concentration and the mass flow ratio of the mixture have significant effects on the system performance of HRVG.

Keywords: Entropy, exergy, ammonia-water mixture, heat exchanger.

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Authors: Mansour Nikpour, Mohd Zin kandar, Mohsen Ghasemi, Hossein Fallah

Abstract:

Over half of the total electricity consumption is used in buildings. Air-conditioning and electric lighting are the two main resources of electricity consumption in high rise buildings. One way to reduce electricity consumption would be to limit heat gain into buildings, therefore reduce the demand for air-conditioning during hot summer months especially in hot regions. On the other hand natural daylight can be used to reduce the use of electricity for artificial lighting. In this paper effective factors on minimizing heat gain and achieving required day light were reviewed .As daylight always accompanied by solar heat gain. Also interactions between heat gain and daylight were discussed through previous studies and equations which are related to heat gain and day lighting especially in high rise buildings. As a result importance of building-s form and its component on energy consumption in buildings were clarified.

Keywords: High rise buildings, energy demand, day lighting, heat gain.

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Authors: D. H. Lee, Nur Irmawati

Abstract:

This paper aims to study the heat transfer and fluid flow characteristics of nanofluids used in spray cooling systems. The effect of spray height, type of nanofluids and concentration of nanofluids are numerically investigated. Five different nanofluids such as AgH2O, Al2O3, CuO, SiO2 and TiO2 with volume fraction range of 0.5% to 2.5% are used. The results revealed that the heat transfer performance decreases as spray height increases. It is found that TiO2 has the highest transfer coefficient among other nanofluids. In dilute spray conditions, low concentration of nanofluids is observed to be more effective in heat removal in a spray cooling system.

Keywords: Numerical simulation, Spray cooling, Heat transfer, Nanofluids.

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Authors: Nosheen Zareen Khan, Abdul Majeed Siddiqui, Muhammad Afzal Rana

Abstract:

The steady flow of a second order fluid through constricted tube with slip velocity at wall is modeled and analyzed theoretically. The governing equations are simplified by implying no slip in radial direction. Based on Karman Pohlhausen procedure polynomial solution for axial velocity profile is presented. Expressions for pressure gradient, shear stress, separation and reattachment points, and radial velocity are also calculated. The effect of slip and no slip velocity on magnitude velocity, shear stress, and pressure gradient are discussed and depicted graphically. It is noted that when Reynolds number increases magnitude velocity of the fluid decreases in both slip and no slip conditions. It is also found that the wall shear stress, separation, and reattachment points are strongly affected by Reynolds number.

Keywords: Approximate solution, constricted tube, non-Newtonian fluids, Reynolds number.

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Authors: Minho Bang, Seok Min Choi, Jun Su Park, Hokyu Moon, Hyung Hee Cho

Abstract:

Present study investigates the effect of unsteady wakes on heat transfer in blade tip. Heat/mass transfer was measured in blade tip region depending on a variety of strouhal number by naphthalene sublimation technique. Naphthalene sublimation technique measures heat transfer using a heat/mass transfer analogy. Experiments are performed in linear cascade which is composed of five turbine blades and rotating rods. Strouhal number of inlet flow are changed ranging from 0 to 0.22. Reynolds number is 100,000 based on 11.4 m/s of outlet flow and axial chord length. Three different squealer tip geometries such as base squealer tip, vertical rib squealer tip, and camber line squealer tip are used to study how unsteady wakes affect heat transfer on a blade tip. Depending on squealer tip geometry, different flow patterns occur on a blade tip. Also, unsteady wakes cause reduced tip leakage flow and turbulent flow. As a result, as strouhal number increases, heat/mass transfer coefficients decrease due to the reduced leakage flow. As strouhal number increases, heat/ mass transfer coefficients on a blade tip increase in vertical rib squealer tip.

Keywords: Gas turbine, blade tip, heat transfer, unsteady wakes.

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Authors: Sanjay Baburao Kulkarni

Abstract:

Exact solution of an unsteady flow of elastico-viscous fluid through a porous media in a tube of ellipsoidal cross section under the influence of constant pressure gradient has been obtained in this paper. Initially, the flow is generated by a constant pressure gradient. After attaining the steady state, the pressure gradient is suddenly withdrawn and the resulting fluid motion in a tube of ellipsoidal cross section by taking into account of the porosity factor of the bounding surface is investigated. The problem is solved in twostages the first stage is a steady motion in tube under the influence of a constant pressure gradient, the second stage concern with an unsteady motion. The problem is solved employing separation of variables technique. The results are expressed in terms of a nondimensional porosity parameter (K) and elastico-viscosity parameter (β), which depends on the Non-Newtonian coefficient. The flow parameters are found to be identical with that of Newtonian case as elastic-viscosity parameter tends to zero and porosity tends to infinity. It is seen that the effect of elastico-viscosity parameter and the porosity parameter of the bounding surface has significant effect on the velocity parameter.

Keywords: Elastico-viscous fluid, Ellipsoidal cross-section, Porous media, Second order fluids.

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Authors: Te Wen Tu, Sen Yung Lee

Abstract:

An alternative approach is proposed to develop the analytic solution for one dimensional heat conduction with one mixed type boundary condition and general time-dependent heat transfer coefficient. In this study, the physic meaning of the solution procedure is revealed. It is shown that the shifting function takes the physic meaning of the reciprocal of Biot function in the initial time. Numerical results show the accuracy of this study. Comparing with those given in the existing literature, the difference is less than 0.3%.

Keywords: Analytic solution, heat transfer coefficient, shifting function method, time-dependent boundary condition.

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Authors: A. H. Sajedi Pour, N. Hedayat, Z. Yazdi

Abstract:

Sediment loads transfer in hydraulic installations and their consequences for the O&M of modern canal systems is emerging as one of the most important considerations in hydraulic engineering projects apriticularly those which are inteded to feed the irrigation and draiange schemes of large command areas such as the Dez and Mogahn in Iran.. The aim of this paper is to investigate the applicability of the vortex tube as a viable means of extracting sediment loads entering the canal systems in general and the water inatke structures in particulars. The Western conveyance canal of the Dez Diversion weir which feeds the Karkheh Flood Plain in Sothwestern Dezful has been used as the case study using the data from the Dastmashan Hydrometric Station. The SHARC software has been used as an analytical framework to interprete the data. Results show that given the grain size D50 and the canal turbulence the adaption length from the beginning of the canal and after the diversion dam is estimated at 477 m, a point which is suitable for laying the vortex tube.

Keywords: Vortex tube, sediments, western canal, SHARCmodel

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Authors: Winai Mankhatitham

Abstract:

This research investigated groundcover on the roof (green roof) which can reduce the temperature and carbon monoxide. This study is divided into 3 main aspects: 1. Types of groundcover affecting heat reduction 2. The efficiency on heat reduction of 3 types of groundcover, i.e. lawn, arachis pintoi, and purslane 3. Database for designing green roof. This study has been designed as an experimental research by simulating the 3 types of groundcover in 3 trays placed in the green house for recording the temperature change for 24 hours. The results showed that the groundcover with the highest heat reduction efficiency was lawn. The dense of the lawn can protect the heat transfer to the soil. For the further study, there should be a comparative study of the thickness and the types of soil to get more information for the suitable types of groundcover and the soil for designing the energy saving green roof.

Keywords: Groundcover, Green Roof, Heat Reduction, Energy Saving.

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Authors: M. Hadi Kusuma, Nandy Putra, Anhar Riza Antariksawan, Ficky Augusta Imawan

Abstract:

Heat pipe is considered to be applied as a passive system to remove residual heat that generated from reactor core when incident occur or from spent fuel storage pool. The objectives are to characterized the heat transfer phenomena, performance of heat pipe, and as a model for large heat pipe will be applied as passive cooling system on nuclear spent fuel pool storage. In this experimental wickless heat pipe or two-phase closed thermosyphon (TPCT) is used. Variation of heat flux are 611.24 Watt/m² - 3291.29 Watt/m². Variation of filling ratio are 45 - 70%. Variation of initial pressure are -62 to -74 cm Hg. Demineralized water is used as working fluid in the TPCT. The results showed that increasing of heat load leads to an increase of evaporation of the working fluid. The optimum filling ratio obtained for 60% of TPCT evaporator volume, and initial pressure variation gave different TPCT wall temperature characteristic. TPCT showed best performance with 60% filling ratio and can be consider to be applied as passive residual heat removal system or passive cooling system on spent fuel storage pool.

Keywords: Two-phase closed thermo syphon, heat pipe, passive cooling, spent fuel storage pool.

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Authors: Liu Xuedong, Liu Hanpeng, Zhou Ling

Abstract:

Study fluid flow and heat transfer characteristics of microchannel in a primary Cross-corrugated(CC) surface recuperators with corrugations and without corrugations, using CFD method. The pitch-over-height ratios P/H of Cross-corrugated (CC) surface is from 1.5 to 4.0, included angles β=75º. The study was performed using CFD software FLUENT to create unit model and simulate fluid temperature, velocity, heat transfer coefficient and other parameters. The results from these simulations were compared to experimental data. It is concluded that, when the Reynolds number is constant, if increase P/H, j/f will decrease, also the decreasing trend will become weak. Under the condition of P/H=2.2, if increase the inlet velocity j/f will decrease; in addition, the heat transfer performance in surface with corrugation will increase 10% compared to that without corrugation. The study results can provide the basis to optimize the design, select the type of heat transfer surface, the scale structure, and heat-transfer surface arrangement for recuperators.

Keywords: Cross-corrugated surface, Primary surface, Numerical simulation, Heat transfer.

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Authors: Mihai Brânzei, Ioan Plotog, Ion Pencea

Abstract:

The Pads have unique values of thermophysical properties (THP) having important contribution over heat transfer into the PCB structure. Materials with high thermal diffusivity (TD) rapidly adjust their temperature to that of their surroundings, because the HT is quick in compare to their volumetric heat capacity (VHC). In the paper is presenting the diffusivity tests (ASTM E1461 flash method) for PCBs with different core materials. In the experiments, the multilayer structure of PCBA was taken into consideration, an equivalent property referring to each of experimental structure be practically measured. Concerning to entire structure, the THP emphasize the major contribution of substrate in establishing of reflow soldering process (RSP) heat transfer necessities. This conclusion offer practical solution for heat transfer time constant calculation as function of thickness and substrate material diffusivity with an acceptable error estimation.

Keywords: heat transfer time constant, packaging, reflowsoldering process, thermal diffusivity.

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Authors: P. K. Gupta

Abstract:

The present paper deals with the experimental and computational study of axial collapse of the aluminum metallic shells having combined tube-frusta geometry between two parallel plates. Shells were having bottom two third lengths as frusta and remaining top one third lengths as tube. Shells were compressed to recognize their modes of collapse and associated energy absorption capability. An axisymmetric Finite Element computational model of collapse process is presented and analysed, using a non-linear FE code FORGE2. Six noded isoparametric triangular elements were used to discretize the deforming shell. The material of the shells was idealized as rigid visco-plastic. To validate the computational model experimental and computed results of the deformed shapes and their corresponding load-compression and energy-compression curves were compared. With the help of the obtained results progress of the axisymmetric mode of collapse has been presented, analysed and discussed.

Keywords: Axial compression, crashworthiness, energy absorption, FORGE2, metallic shells.

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Authors: Ashwin Bala, K. Panthalaraja Kumaran, S. Prithviraj, R. Pradeep, J. Udhayakumar, S. Ajith

Abstract:

In this paper comprehensive studies have been carried out for the design optimization of a waste heat recovery system for effectively utilizing the domestic air conditioner heat energy for producing hot water. Numerical studies have been carried for the geometry optimization of a waste heat recovery system for domestic air conditioners. Numerical computations have been carried out using a validated 2d pressure based, unsteady, 2nd-order implicit, SST k-ω turbulence model. In the numerical study, a fully implicit finite volume scheme of the compressible, Reynolds-Averaged, Navier- Stokes equations is employed. At identical inflow and boundary conditions various geometries were tried and effort has been taken for proposing the best design criteria. Several combinations of pipe line shapes viz., straight and spiral with different number of coils for the radiator have been attempted and accordingly the design criteria has been proposed for the waste heat recovery system design. We have concluded that, within the given envelope, the geometry optimization is a meaningful objective for getting better performance of waste heat recovery system for air conditioners.

Keywords: Air-conditioning system, Energy conversion system, Hot water production from waste heat, Waste heat recovery system.

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Authors: Alnouss M. Ahmed, Al-Nuaimi A. Ibrahim

Abstract:

In this paper, the energy performance of a selected UHDE Ammonia plant is optimized by conducting heat integration through waste heat recovery and the synthesis of a heat exchange network (HEN). Minimum hot and cold utility requirements were estimated through IChemE spreadsheet. Supporting simulation was carried out using HYSYS software. The results showed that there is no need for heating utility while the required cold utility was found to be around 268,714 kW. Hence a threshold pinch case was faced. Then, the hot and cold streams were matched appropriately. Also, waste heat recovered resulted with savings in HP and LP steams of approximately 51.0% and 99.6%, respectively. An economic analysis on proposed HEN showed very attractive overall payback period not exceeding 3 years. In general, a net saving approaching 35% was achieved in implementing heat optimization of current studied UHDE Ammonia process.

Keywords: Ammonia, Energy Optimization, Heat Exchange Network and Techno-Economic Analysis.

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Authors: U. Prasopchingchana

Abstract:

The temperature distribution and the heat transfer rates through a multi-layer door of a furnace were investigated. The inside of the door was in contact with hot air and the other side of the door was in contact with room air. Radiation heat transfer from the walls of the furnace to the door and the door to the surrounding area was included in the problem. This work is a two dimensional steady state problem. The Churchill and Chu correlation was used to find local convection heat transfer coefficients at the surfaces of the furnace door. The thermophysical properties of air were the functions of the temperatures. Polynomial curve fitting for the fluid properties were carried out. Finite difference method was used to discretize for conduction heat transfer within the furnace door. The Gauss-Seidel Iteration was employed to compute the temperature distribution in the door. The temperature distribution in the horizontal mid plane of the furnace door in a two dimensional problem agrees with the one dimensional problem. The local convection heat transfer coefficients at the inside and outside surfaces of the furnace door are exhibited.

Keywords: Conduction, heat transfer, multi-layer door, natural convection

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Authors: Sanjay Baburao Kulkarni

Abstract:

Exact solution of an unsteady MHD flow of elasticoviscous fluid through a porous media in a tube of spherical cross section under the influence of magnetic field and constant pressure gradient has been obtained in this paper. Initially, the flow is generated by a constant pressure gradient. After attaining the steady state, the pressure gradient is suddenly withdrawn and the resulting fluid motion in a tube of spherical cross section by taking into account of the porosity factor and magnetic parameter of the bounding surface is investigated. The problem is solved in two-stages the first stage is a steady motion in tube under the influence of a constant pressure gradient, the second stage concern with an unsteady motion. The problem is solved employing separation of variables technique. The results are expressed in terms of a non-dimensional porosity parameter (K), magnetic parameter (m) and elasticoviscosity parameter (β), which depends on the Non-Newtonian coefficient. The flow parameters are found to be identical with that of Newtonian case as elastic-viscosity parameter and magnetic parameter tends to zero and porosity tends to infinity. It is seen that the effect of elastico-viscosity parameter, porosity parameter and magnetic parameter of the bounding surface has significant effect on the velocity parameter.

Keywords: Elastico-viscous fluid, Porous media, Second order fluids, Spherical cross-section, Magnetic parameter.

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Authors: K. Hiro, T. Wada

Abstract:

Thermodynamic properties of liquids under negative pressures are interesting and important in fields of scienceand technology. Here, phase transitions of a thermotropic liquid crystal are investigatedin a range from positive to negative pressures with a metal Berthelot tube using a commercial pressure transducer.Two co-existinglines, namely crystal (Kr) –nematic (N), and isotropic liquid (I) - nematic (N) lines, weredrawn in a pressure - temperature plane. The I-N line was drawn to ca. -5 (MPa).

Keywords: Berthelot method, liquid crystal, negative pressure.

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Authors: M. Esmailian, M. Shakouri, A. Mottahedi, S. G. Shabestari

Abstract:

Heat treatable aluminum alloys such as 7075 and 7055, because of high strength and low density, are used widely in aircraft industry. For best mechanical properties, T6 heat treatment has recommended for this regards, but this temper treatment is sensitive to corrosion induced and Stress Corrosion Cracking (SCC) damage. For improving this property, the over-aging treatment (T7) applies to this alloy, but it decreases the mechanical properties up to 30 percent. Hence, to increase the mechanical properties, without any remarkable decrease in SCC resistant, Retrogression and Re-Aging (RRA) heat treatment is used. This treatment performs in a relatively short time. In this paper, the RRA heat treatment was applied to 7055 aluminum alloy and then effect of RRA time on the mechanical properties of 7055 has been investigated. The results show that the 40-minute time is suitable time for retrogression of 7055 aluminum alloy and ultimate strength increases up to 625MPa.

Keywords: 7055 Aluminum alloy, Mechanical properties, SCC resistance, Heat Treatment.

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Authors: Yu-Ching Yang, Haw-Long Lee, Win-Jin Chang

Abstract:

The present work numerically analyzes the transient heat transfer in the absorber plates of a flat-plate solar collector based on the dual-phase-lag (DPL) heat conduction model. An efficient numerical scheme involving the hybrid application of the Laplace transform and control volume methods is used to solve the linear hyperbolic heat conduction equation. This work also examines the effect of different medium parameters on the behavior of heat transfer. Results show that, while the heat-flux phase lag induces thermal waves in the medium, the temperature-gradient phase lag smoothens the thermal waves by promoting non-Fourier diffusion-like conduction into the medium.

Keywords: Absorber plates, dual-phase-lag, non-Fourier, solar collector.

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Authors: J. Mlýnek, R. Srb

Abstract:

This article is focused on the calculation of heat radiation intensity and its optimization on an aluminum mould surface. The inside of the mould is sprinkled with a special powder and its outside is heated by infra heaters located above the mould surface, up to a temperature of 250°C. By this way artificial leathers in the car industry are produced (e. g. the artificial leather on a car dashboard). A mathematical model of heat radiation of infra heaters on a mould surface is described in this paper. This model allows us to calculate a heat-intensity radiation on the mould surface for the concrete location of infra heaters above the mould surface. It is necessary to ensure approximately the same heat intensity radiation on the mould surface by finding a suitable location for the infra heaters, and in this way the same material structure and color of artificial leather. In the model we have used a genetic algorithm to optimize the radiation intensity on the mould surface. Experimental measured values for the heat radiation intensity by a sensor in the surroundings of an infra heater are used for the calculation procedures. A computational procedure was programmed in language Matlab.

Keywords: Genetic algorithm, mathematical model of heat radiation, optimization of radiation intensity, software implementation

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Authors: H. R. Goshayeshi, M. Mansori, M. Ahmady, M. Khaloyi

Abstract:

This paper presents the result of an experimental investigation regarding the use of Fe2O3 nanoparticles added to kerosene as a working fluid, under magnetic field for Copper Oscillating Heat pipe with inclination angle of 0°(horizontal), 15°, 30°,45°, 60°,75° and 90° (vertical). The following were examined; measure the temperature distribution and heat transfer rate on Oscillating Heat Pipe (OHP), with magnetic field under different angles. Results showed that the addition of Fe2O3 nanoparticles under magnetic field improved thermal performance of OHP especially in 75°.

Keywords: Copper oscillating heat pipe, Fe2O3, magnetic field, inclination angles.

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Authors: B. Käfer, V. K. Bheemineni, H. Lammer, M. Kotnik, F. O. Riemelmoser

Abstract:

Axial compression tests are performed on circular tubes made of Aluminum EN AW 6060 (AlMgSi0.5 alloy) in T66 state. All the received tubes have the uniform outer diameter of 40mm and thickness of 1.5mm. Two different lengths 100mm and 200mm are used in the analysis. After performing compression tests on the uniform tube, important crashworthy parameters like peak force, average force, crush efficiency and energy absorption are measured. The present paper has given importance to increase the percentage of crush efficiency without decreasing the value energy absorption of a tube, so a circumferential notch was introduced on the top section of the tube. The effects of position and cut-out lengths of a circumferential notch on the crush efficiency are well explained with relative deformation modes and force-displacement curves. The numerical simulations were carried on the software tool ANSYS/LS-DYNA. It is seen that the numerical results are reasonably good in agreement with the experimental results. 

Keywords: Crash box, Notch triggering, Energy absorption, FEM simulation.

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Authors: Mohamed Ammar Abbassi, Kamel Guedri, Mohamed Naceur Borjini, Kamel Halouani, Belkacem Zeghmati

Abstract:

The radiative heat transfer problem is investigated numerically for 2D complex geometry biomass pyrolysis reactor composed of two pyrolysis chambers and a heat recuperator. The fumes are a mixture of carbon dioxide and water vapor charged with absorbing and scattering particles and soot. In order to increase gases residence time and heat transfer, the heat recuperator is provided with many inclined, vertical, horizontal, diffuse and grey baffles of finite thickness and has a complex geometry. The Finite Volume Method (FVM) is applied to study radiative heat transfer. The blocked-off region procedure is used to treat the geometrical irregularities. Eight cases are considered in order to demonstrate the effect of adding baffles on the walls of the heat recuperator and on the walls of the pyrolysis rooms then choose the best case giving the maximum heat flux transferred to the biomass in the pyrolysis chambers. Ray effect due to the presence of baffles is studied and demonstrated to have a crucial effect on radiative heat flux on the walls of the pyrolysis rooms. Shadow effect caused by the presence of the baffles is also studied. The non grey radiative heat transfer is studied for the real existent configuration. The Weighted Sum of The Grey Gases (WSGG) Model of Kim and Song is used as non grey model. The effect of soot volumetric fraction on the non grey radiative heat flux is investigated and discussed.

Keywords: Baffles, Blocked-off region procedure, FVM, Heat recuperation, Radiative heat transfer, Shadow effect.

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Authors: A. M. Tahsini, S. A. Hosseini

Abstract:

In the present study, the surface temperature history of the adaptor part in a two-stage supersonic launch vehicle is accurately predicted. The full Navier-Stokes equations are used to estimate the aerodynamic heat flux and the one-dimensional heat conduction in solid phase is used to compute the temperature history. The instantaneous surface temperature is used to improve the applied heat flux, to improve the accuracy of the results.

Keywords: Aerodynamic heating, Heat conduction, Numerical simulation, Supersonic flight, Launch vehicle.

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Authors: Murat Sarıkaya, Abdulkadir Güllü

Abstract:

Haynes 25 alloy (also known as L-605 alloy) is cobalt based super alloy which has widely applications such as aerospace industry, turbine and furnace parts, power generators and heat exchangers and petroleum refining components due to its excellent characteristics. However, the workability of this alloy is more difficult compared to normal steels or even stainless. In present work, an experimental investigation was performed under cryogenic cooling to determine cutting tool wear patterns and obtain optimal cutting parameters in turning of cobalt based superalloy Haynes 25. In experiments, uncoated carbide tool was used and cutting speed (V) and feed rate (f) were considered as test parameters. Tool wear (VBmax) were measured for process performance indicators. Analysis of variance (ANOVA) was performed to determine the importance of machining parameters.

Keywords: Cryogenic machining, difficult-to-cut alloy, tool wear, turning.

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Authors: Masaki Yamaguchi, Akira Ito, Noriaki Okamoto, Yoshinori Kawabe, Masamichi Kamihira

Abstract:

Heat-inducible gene expression vectors are useful for hyperthermia-induced cancer gene therapy, because the combination of hyperthermia and gene therapy can considerably improve the therapeutic effects. In the present study, we developed an enhanced heat-inducible transgene expression system in which a heat-shock protein (HSP) promoter and tetracycline-responsive transactivator were combined. When the transactivator plasmid containing the tetracycline-responsive transactivator gene was co-transfected with the reporter gene expression plasmid, a high level of heat-induced gene expression was observed compared with that using the HSP promoter without the transactivator. In vitro evaluation of the therapeutic effect using HeLa cells showed that heat-induced therapeutic gene expression caused cell death in a high percentage of these cells, indicating that this strategy is promising for cancer gene therapy.

Keywords: Inducible gene expression, Gene therapy, Hyperthermia, Heat shock protein, Tetracycline transactivator.

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Authors: N. Targui, H. Kahalerras

Abstract:

The present work is a numerical simulation of nanofluids flow in a double pipe heat exchanger provided with porous baffles. The hot nanofluid flows in the inner cylinder, whereas the cold nanofluid circulates in the annular gap. The Darcy- Brinkman-Forchheimer model is adopted to describe the flow in the porous regions, and the governing equations with the appropriate boundary conditions are solved by the finite volume method. The results reveal that the addition of metallic nanoparticles enhances the rate of heat transfer in comparison to conventional fluids but this augmentation is accompanied by an increase in pressure drop. The highest heat exchanger performances are obtained when nanoparticles are added only to the cold fluid.

Keywords: Double pipe heat exchanger, Nanofluids, Nanoparticles, Porous baffles.

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Authors: Norfifah Bachok, Norihan Md. Arifin

Abstract:

In this paper we use classical linear stability theory to investigate the effects of uniform internal heat generation on the onset of Marangoni convection in a horizontal layer of fluid heated from below. We use a analytical technique to obtain the close form analytical expression for the onset of Marangoni convection when the lower boundary is conducting with free-slip condition. We show that the effect of increasing the internal heat generation is always to destabilize the layer.

Keywords: Marangoni convection, heat generation, free-slip

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