Search results for: Coronary blood flow
2462 Hypolipidemic and Antioxidant Effects of Black Tea Extract and Quercetin in Atherosclerotic Rats
Authors: Wahyu Widowati, Hana Ratnawati, Tjandrawati Mozefis, Dwiyati Pujimulyani, Yelliantty Yelliantty
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Background: Atherosclerosis is the main cause of cardiovascular disease (CVD) with complex and multifactorial process including atherogenic lipoprotein, oxidized low density lipoprotein (LDL), endothelial dysfunction, plaque stability, vascular inflammation, thrombotic and fibrinolytic disorder, exercises and genetic factor Epidemiological studies have shown tea consumption inversely associated with the development and progression of atherosclerosis. The research objectives: to elucidate hypolipidemic, antioxidant effects, as well as ability to improve coronary artery’s histopathologyof black tea extract (BTE) and quercetin in atherosclerotic rats. Methods: The antioxidant activity was determined by using Superoxide Dismutase activity (SOD) of serum and lipid peroxidation product (Malondialdehyde) of plasma and lipid profile including cholesterol total, LDL, triglyceride (TG), High Density Lipoprotein (HDL) of atherosclerotic rats. Inducing atherosclerotic, rats were given cholesterol and cholic acid in feed during ten weeks until rats indicated atherosclerotic symptom with narrowed artery and foamy cells in the artery’s wall. After rats suffered atherosclerotic, the high cholesterol feed and cholic acid were stopped and rats were given BTE 450; 300; 150 mg/kg body weight (BW) daily, quercetin 15; 10; 5 mg/kg BW daily, compared to rats were given vitamin E 60 mg/kg/BW; simvastatin 2.7 mg/kg BW, probucol 30 mg/kg BW daily for 21 days (first treatment) and 42 days (second treatment), negative control (normal feed), positive control (atherosclerotic rats). Results: BTE and quercetin could lower cholesterol total, triglyceride, LDL MDA and increase HDL, SOD were comparable with simvastatin, probucol both for 21 days and 42 days treatment, as well to improve coronary arteries histopathology. Conclusions: BTE andquercetin have hypolipidemic and antioxidant effects, as well as improve coronary arteries histopathology in atherosclerotic rats.
Keywords: Black tea, quercetin, atherosclerosis, antioxidant, hypolipidemic, cardiovascular disease.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 27222461 Effects of Rarefaction and Compressibility on Fluid Flow at Slip Flow Regime by Direct Simulation of Roughness
Authors: M. Hakak Khadem, M. Shams, S. Hossainpour
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A two dimensional numerical simulation has been performed for incompressible and compressible fluid flow through microchannels in slip flow regime. The Navier-Stokes equations have been solved in conjunction with Maxwell slip conditions for modeling flow field associated with slip flow regime. The wall roughness is simulated with triangular microelements distributed on wall surfaces to study the effects of roughness on fluid flow. Various Mach and Knudsen numbers are used to investigate the effects of rarefaction as well as compressibility. It is found that rarefaction has more significant effect on flow field in microchannels with higher relative roughness. It is also found that compressibility has more significant effects on Poiseuille number when relative roughness increases. In addition, similar to incompressible models the increase in average fRe is more significant at low Knudsen number flows but the increase of Poiseuille number duo to relative roughness is sharper for compressible models. The numerical results have also validated with some available theoretical and experimental relations and good agreements have been seen.Keywords: Relative roughness, slip flow, Poiseuille number.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 14062460 A Neural Network Approach in Predicting the Blood Glucose Level for Diabetic Patients
Authors: Zarita Zainuddin, Ong Pauline, C. Ardil
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Diabetes Mellitus is a chronic metabolic disorder, where the improper management of the blood glucose level in the diabetic patients will lead to the risk of heart attack, kidney disease and renal failure. This paper attempts to enhance the diagnostic accuracy of the advancing blood glucose levels of the diabetic patients, by combining principal component analysis and wavelet neural network. The proposed system makes separate blood glucose prediction in the morning, afternoon, evening and night intervals, using dataset from one patient covering a period of 77 days. Comparisons of the diagnostic accuracy with other neural network models, which use the same dataset are made. The comparison results showed overall improved accuracy, which indicates the effectiveness of this proposed system.Keywords: Diabetes Mellitus, principal component analysis, time-series, wavelet neural network.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 29772459 Anaplasmosis among Camels in Iran and Observation of Abnormalities in Infected Blood Films
Authors: Khosro Ghazvinian, Touba Khodaiean
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Anaplasma organisms are obligatory intracellular bacteria belonging to the order Rickettsiales, family Anaplasmataceae. This disease is distributed around the globe and infected ticks are the most important vectors in anaplasmosis transmission. There is a little information about anaplasmosis in camels. This research investigated the blood films of 35 (20 male, 15 female) camels randomly selected from a flock of 150 camels. Samples were stained with Giemsa and Anaplasma sp. organisms were observed in six out of 35 (17.14 %) blood films. There were also some changes in Diff-Quick and morphology of leukocytes. No significant difference between male and female camels was observed (P>0.05). According to the results anaplasmosis is presented among camels in Iran.
Keywords: Anaplasma, camel, anaplasmosis, Iran.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 10272458 Numerical Simulation and Experimental Validation of the Hydraulic L-Shaped Check Ball Behavior
Authors: Shinji Kajiwara
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The spring-driven ball-type check valve is one of the most important components of hydraulic systems: it controls the position of the ball and prevents backward flow. To simplify the structure, the spring must be eliminated, and to accomplish this, the flow pattern and the behavior of the check ball in L-shaped pipe must be determined. In this paper, we present a full-scale model of a check ball made of acrylic resin, and we determine the relationship between the initial position of the ball, the position and diameter of the inflow port. The check flow rate increases in a standard center inflow model, and it is possible to greatly decrease the check-flow rate by shifting the inflow from the center.
Keywords: Hydraulics, Pipe Flow, Numerical Simulation, Flow Visualization, Check ball, L-shaped Pipe.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20682457 Numerical Study of Liquefied Petroleum Gas Laminar Flow in Cylindrical Elliptic Pipes
Authors: Olumuyiwa A. Lasode, Tajudeen O. Popoola, B. V. S. S. S. Prasad
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Fluid flow in cylinders of elliptic cross-section was investigated. Fluid used is Liquefied petroleum gas (LPG). LPG found in Nigeria contains majorly butane with percentages of propane. Commercial available code FLUENT which uses finite volume method was used to solve fluid flow governing equations. There has been little attention paid to fluid flow in cylindrical elliptic pipes. The present work aims to predict the LPG gas flow in cylindrical pipes of elliptic cross-section. Results of flow parameters of velocity and pressure distributions are presented. Results show that the pressure drop in elliptic pipes is higher than circular pipe of the same cross-sectional area. This is an important result as the pressure drop is related to the pump power needed to drive the flow. Results show that the velocity increases towards centre of the pipe as the flow moves downstream, and also increases towards the outlet of the pipe.
Keywords: Elliptic Pipes, Liquefied Petroleum Gas, Numerical Study, Pressure Drop.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 28972456 Investigation of Increasing the Heat Transfer from Flat Surfaces Using Boundary Layer Excitation
Authors: M.H.Ghaffari
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The present study is concerned with effect of exciting boundary layer on increase in heat transfer from flat surfaces. As any increase in heat transfer between a fluid inside a face and another one outside of it can cause an increase in some equipment's efficiency, so at this present we have tried to increase the wall's heat transfer coefficient by exciting the fluid boundary layer. By a collision between flow and the placed block at the fluid way, the flow pattern and the boundary layer stability will change. The flow way inside the channel is simulated as a 2&3-dimensional channel by Gambit TM software. With studying the achieved results by this simulation for the flow way inside the channel with a block coordinating with Fluent TM software, it's determined that the figure and dimensions of the exciter are too important for exciting the boundary layer so that any increase in block dimensions in vertical side against the flow and any reduction in its dimensions at the flow side can increase the average heat transfer coefficient from flat surface and increase the flow pressure loss. Using 2&3-dimensional analysis on exciting the flow at the flow way inside a channel by cylindrical block at the same time with the external flow, we came to this conclusion that the heat flux transferred from the surface, is increased considerably in terms of the condition without excitation. Also, the k-e turbulence model is used.Keywords: Cooling, Heat transfer, Turbulence, Excitingboundary layer.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 11882455 CFD Effect of the Tidal Grating in Opposite Directions
Authors: N. M. Thao, I. Dolguntseva, M. Leijon
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Flow blockages referring to the increase in flow are being considered as a vital equipment for marine current energy conversion. However, the shape of these devices will result in extracted energy under the operation. The present work investigates the effect of two configurations of a grating, convergent and divergent that located upstream, to the water flow velocity. The flow characteristics are studied by Computational Fluid Dynamic simulation by using the ANSYS Fluent solver for these specified arrangements of the grating. The results indicate that distinguished characteristics of flow velocity between “convergent” and “divergent” grating placements is up to 10% in confined conditions. Furthermore, the velocity in case of convergent grating is higher than that of divergent grating.
Keywords: Marine current energy, marine current energy converter, turbine grating, RANS simulation, water flow velocity.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 17092454 Multi-Line Power Flow Control using Interline Power Flow Controller (IPFC) in Power Transmission Systems
Authors: A.V.Naresh Babu, S.Sivanagaraju, Ch.Padmanabharaju, T.Ramana
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The interline power flow controller (IPFC) is one of the latest generation flexible AC transmission systems (FACTS) controller used to control power flows of multiple transmission lines. This paper presents a mathematical model of IPFC, termed as power injection model (PIM). This model is incorporated in Newton- Raphson (NR) power flow algorithm to study the power flow control in transmission lines in which IPFC is placed. A program in MATLAB has been written in order to extend conventional NR algorithm based on this model. Numerical results are carried out on a standard 2 machine 5 bus system. The results without and with IPFC are compared in terms of voltages, active and reactive power flows to demonstrate the performance of the IPFC model.Keywords: flexible AC transmission systems (FACTS), interline power flow controller (IPFC), power injection model (PIM), power flow control.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 29792453 Sensitivity Comparison between Rapid Immuno-Chromatographic Device Test and ELISA in Detection and Sero-Prevalence of HBsAg and Anti-HCV antibodies in Apparently Healthy Blood Donors of Lahore, Pakistan
Authors: Natasha Hussain, Maleeha Aslam, Robina Farooq
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Hepatitis B and hepatitis C are among the most significant hepatic infections all around the world that may lead to hepatocellular carcinoma. This study is first time performed at the blood transfussion centre of Omar hospital, Lahore. It aims to determine the sero-prevalence of these diseases by screening the apparently healthy blood donors who might be the carriers of HBV or HCV and pose a high risk in the transmission. It also aims the comparison between the sensitivity of two diagnostic tests; chromatographic immunoassay – one step test device and Enzyme Linked Immuno Sorbant Assay (ELISA). Blood serum of 855 apparently healthy blood donors was screened for Hepatitis B surface antigen (HBsAg) and for anti HCV antibodies. SPSS version 12.0 and X2 (Chi-square) test were used for statistical analysis. The seroprevalence of HCV was 8.07% by the device method and by ELISA 9.12% and that of HBV was 5.6% by the device and 6.43% by ELISA. The unavailability of vaccination against HCV makes it more prevalent. Comparing the two diagnostic methods, ELISA proved to be more sensitive.Keywords: ELISA, Sensitivity comparison of diagnostic tests, seroprevalence of Hepatitis B and C
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 21812452 Serum Nitric Oxide and Sialic Acid: Possible Biochemical Markers for Progression of Diabetic Nephropathy
Authors: Syed M. Shahid, Rozeena Shaikh, Syeda N. Nawab, Shah A. Qader, Abid Azhar, Tabassum Mahboob
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This study was designed to investigate the role of serum nitric oxide and sialic acid in the development of diabetic nephropathy as disease marker. Total 210 diabetic patients (age and sex matched) were selected followed by informed consent and divided into four groups (70 each) as I: control; II: diabetic; III: diabetic hypertensive; IV: diabetic nephropathy. The blood samples of all subjects were collected and analyzed for serum nitric oxide, sialic acid, fasting blood glucose, serum urea, creatinine, HbA1c and GFR. The BMI, systolic and diastolic blood pressures, blood glucose, HbA1c and serum sialic acid levels were high (p<0.01) in group II as compared to control subjects. The higher levels (p<0.01) of BMI, systolic and diastolic blood pressures, blood glucose, HbA1c, serum urea, creatinine and sialic acid were observed in group III and IV as compared to controls. Significantly low levels of GFR and serum nitric oxide (p<0.01) were observed in group III and IV as compared to controls. Results indicated that serum nitric oxide and sialic acid are the major biochemical indicators for micro and macrovascular complications of diabetes such as hypertension and nephropathy. These should be taken into account during screening procedures regarding identifications of the diabetic patients to get them rid of progressive renal impairment to ESRD.
Keywords: Diabetic nephropathy, hypertension, nitric oxide, sialic acid.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16822451 Fluid Flow Analysis and Design of a Flow Distributor in a Domestic Gas Boiler Using a Commercial CFD Software
Authors: Lukasz Peronski, Roy Bratley, Derek B. Ingham, Lin Ma, Mohamed Pourkashanian, StephenTaylor
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The aim of the study was to investigate the possible use of commercial Computational Fluid Dynamics (CFD) software in the design process of a domestic gas boiler. Because of the limited computational resources some simplifications had to be made in order to contribute to the design in a reasonable timescale. The porous media model was used in order to simulate the influence of the pressure drop characteristic of particular elements of a heat transfer system on the water-flow distribution in the system. Further, a combination of CFD analyses and spread sheet calculations was used in order to solve the flow distribution problem.Keywords: CFD, domestic gas boilers, flow distribution, heatexchanger, porous media
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 27262450 The Alterations of Some Pancreas Gland Hormones after an Aerobic Strenuous Exercise in Male Students
Authors: M. Javad Pourvaghar, A. Reza Shahsavar
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The alterations in pancreas gland secretion hormones following an aerobic and exhausting exercise was the purpose of this study. Sixteen healthy men participated in the study. The blood samples of these participants were taken in four stages under fasting condition. The first sample was taken before Bruce exhausting and aerobic test, the second sample was taken after Bruce exercise and the third and forth stages samples were taken 24 and 48 hours after the exercises respectively. The final results indicated that a strenuous aerobic exercise can have a significant effect on glucagon and insulin concentration of blood serum. The increase in blood serum insulin was higher after 24 and 48 hours. It seems that an intensive exercise has little effect on changes in glucagon concentration of blood serum. Also, disorder in secretion in glucagon and insulin concentration of serum disturbs athletes- exercise.Keywords: Intensive Exercise, Bruce Protocol, Glucagon, Insulin
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 14162449 The Experimental Study of the Effect of Flow Pattern Geometry on Performance of Micro Proton Exchange Membrane Fuel Cell
Authors: Tang Yuan Chen, Chang Hsin Chen, Chiun Hsun Chen
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In this research, the flow pattern influence on performance of a micro PEMFC was investigated experimentally. The investigation focused on the impacts of bend angels and rib/channel dimensions of serpentine flow channel pattern on the performance and investigated how they improve the performance. The fuel cell employed for these experiments was a micro single PEMFC with a membrane of 1.44 cm2 Nafion NRE-212. The results show that 60° and 120° bend angles can provide the better performances at 20 and 40 sccm inlet flow rates comparing to that the conventional design. Additionally, wider channel with narrower rib spacing gives better performance. These results may be applied to develop universal heuristics for the design of flow pattern of micro PEMFC.Keywords: Flow pattern, MEMS, PEMFC, Performance
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16972448 Effect of Fractional Flow Curves on the Heavy Oil and Light Oil Recoveries in Petroleum Reservoirs
Authors: Abdul Jamil Nazari, Shigeo Honma
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This paper evaluates and compares the effect of fractional flow curves on the heavy oil and light oil recoveries in a petroleum reservoir. Fingering of flowing water is one of the serious problems of the oil displacement by water and another problem is the estimation of the amount of recover oil from a petroleum reservoir. To address these problems, the fractional flow of heavy oil and light oil are investigated. The fractional flow approach treats the multi-phases flow rate as a total mixed fluid and then describes the individual phases as fractional of the total flow. Laboratory experiments are implemented for two different types of oils, heavy oil, and light oil, to experimentally obtain relative permeability and fractional flow curves. Application of the light oil fractional curve, which exhibits a regular S-shape, to the water flooding method showed that a large amount of mobile oil in the reservoir is displaced by water injection. In contrast, the fractional flow curve of heavy oil does not display an S-shape because of its high viscosity. Although the advance of the injected waterfront is faster than in light oil reservoirs, a significant amount of mobile oil remains behind the waterfront.
Keywords: Fractional flow curve, oil recovery, relative permeability, water fingering.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 14622447 Aerodynamic Designing of Supersonic Centrifugal Compressor Stages
Authors: Y. Galerkin, A. Rekstin, K. Soldatova
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Universal modeling method well proven for industrial compressors was applied for design of the high flow rate supersonic stage. Results were checked by ANSYS CFX and NUMECA Fine Turbo calculations. The impeller appeared to be very effective at transonic flow velocities. Stator elements efficiency is acceptable at design Mach numbers too. Their loss coefficient versus inlet flow angle performances correlates well with Universal modeling prediction. The impeller demonstrates ability of satisfactory operation at design flow rate. Supersonic flow behavior in the impeller inducer at the shroud blade to blade surface Φ des deserves additional study.
Keywords: Centrifugal compressor stage, supersonic impeller, inlet flow angle, loss coefficient, return channel, shock wave, vane diffuser.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 31972446 Description of Unsteady Flows in the Cuboid Container
Authors: K. Horáková, K. Fraňa, V. Honzejk
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This part of study deals with description of unsteady isothermal melt flow in the container with cuboid shape. This melt flow is driven by rotating magnetic field. Input data (instantaneous velocities, grid coordinates and Lorentz forces) were obtained from in-house CFD code (called NS-FEM3D) which uses DDES method of computing. Description of the flow was performed by contours of Lorentz forces and caused velocity field. Taylor magnetic numbers of the flow were used 1.10^6, 5.10^6 and 1.10^7, flow was in 3D turbulent flow regime.
Keywords: In-house computing code, Lorentz forces, magnetohydrodynamics, rotating magnetic field.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 15792445 Flow Characteristics of Pulp Liquid in Straight Ducts
Authors: M. Sumida
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An experimental investigation was performed on pulp liquid flow in straight ducts with a square cross section. Fully developed steady flow was visualized and the fiber concentration was obtained using a light-section method developed by the author et al. The obtained results reveal quantitatively, in a definite form, the distribution of the fiber concentration. From the results and measurements of pressure loss, it is found that the flow characteristics of pulp liquid in ducts can be classified into five patterns. The relationships among the distributions of mean and fluctuation of fiber concentration, the pressure loss and the flow velocity are discussed, and then the features for each pattern are extracted. The degree of nonuniformity of the fiber concentration, which is indicated by the standard deviation of its distribution, is decreased from 0.3 to 0.05 with an increase in the velocity of the tested pulp liquid from 0.4 to 0.8%.Keywords: Fiber Concentration, Flow Characteristic, Pulp Liquid, Straight Duct.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 15682444 Numerical Simulation of the Turbulent Flow over a Three-Dimensional Flat Roof
Authors: M. Raciti Castelli, A. Castelli, E. Benini
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The flow field over a flat roof model building has been numerically investigated in order to determine threedimensional CFD guidelines for the calculation of the turbulent flow over a structure immersed in an atmospheric boundary layer. To this purpose, a complete validation campaign has been performed through a systematic comparison of numerical simulations with wind tunnel experimental data. Wind tunnel measurements and numerical predictions have been compared for five different vertical positions, respectively from the upstream leading edge to the downstream bottom edge of the analyzed model. Flow field characteristics in the neighborhood of the building model have been numerically investigated, allowing a quantification of the capabilities of the CFD code to predict the flow separation and the extension of the recirculation regions. The proposed calculations have allowed the development of a preliminary procedure to be used as guidance in selecting the appropriate grid configuration and corresponding turbulence model for the prediction of the flow field over a three-dimensional roof architecture dominated by flow separation.
Keywords: CFD, roof, building, wind
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 17222443 Facilitating Cooperative Knowledge Support by Role-Based Knowledge-Flow Views
Authors: Chih-Wei Lin, Duen-Ren Liu, Hui-Fang Chen
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Effective knowledge support relies on providing operation-relevant knowledge to workers promptly and accurately. A knowledge flow represents an individual-s or a group-s knowledge-needs and referencing behavior of codified knowledge during operation performance. The flow has been utilized to facilitate organizational knowledge support by illustrating workers- knowledge-needs systematically and precisely. However, conventional knowledge-flow models cannot work well in cooperative teams, which team members usually have diverse knowledge-needs in terms of roles. The reason is that those models only provide one single view to all participants and do not reflect individual knowledge-needs in flows. Hence, we propose a role-based knowledge-flow view model in this work. The model builds knowledge-flow views (or virtual knowledge flows) by creating appropriate virtual knowledge nodes and generalizing knowledge concepts to required concept levels. The customized views could represent individual role-s knowledge-needs in teamwork context. The novel model indicates knowledge-needs in condensed representation from a roles perspective and enhances the efficiency of cooperative knowledge support in organizations.Keywords: cooperative knowledge support, knowledge flow, knowledge-flow view, role-based models
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 12872442 Effect of Secondary Curvature on Mixing Characteristic within Constant Circular Tubes
Authors: Minh Tuan Nguyen, Sang-Wook Lee
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In this study, numerical simulations on laminar flow in sinusoidal wavy shaped tubes were conducted for mean Reynolds number of 250, which is in the range of physiological flow-rate and investigated flow structures, pressure distribution and particle trajectories both in steady and periodic inflow conditions. For extensive comparisons, various wave lengths and amplitudes of sine function for geometry of tube models were employed. The results showed that small amplitude secondary curvature has significant influence on the nature of flow patterns and particle mixing mechanism. This implies that characterizing accurate geometry is essential in accurate predicting of in vivo hemodynamics and may motivate further study on any possibility of reflection of secondary flow on vascular remodeling and pathophysiology.Keywords: Secondary curvature, Sinusoidal wavy tubes, Mixing Characteristics, Pulsatile flow, Hemodynamics.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 15872441 Numerical Investigation of Flow Past Cylinderin Cross Flow
Authors: M. H. Alhajeri, Jasem Alrajhi, Mohsen Alardhi, Saleh Alhajeri
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A numerical prediction of flow in a tube bank is reported. The flow regimes considered cover a wide range of Reynolds numbers, which range from 380 to 99000 and which are equivalent to a range of inlet velocities from very low (0.072 m/s) to very high (60 m/s). In this study, calculations were made using the standard k-e model with standard wall function. The drag coefficient, skin friction drag, pressure drag, and pressure distribution around a tube were investigated. As the velocity increased, the drag coefficient decreased until the velocity exceeded 45 m/s, after which it increased. Furthermore, the pressure drag and skin friction drag depend on the velocity.
Keywords: Numerical, Fluid, Flow, Turbine, Cooling, Blade.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19672440 Vortex Shedding on Combined Bodies at Incidence to a Uniform Air Stream
Authors: T. Yavuz, Y. E. Akansu, M. Sarıoglu, M. Ozmert
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Vortex-shedding phenomenon of the flow around combined two bodies having various geometries and sizes has been investigated experimentally in the Reynolds number range between 4.1x103 and 1.75x104. To see the effect of the rotation of the bodies on the vortex shedding, the combined bodies were rotated from 0° to 180°. The combined models have a cross section composing of a main circular cylinder and an attached circular or square cylinder. Results have shown that Strouhal numbers for two cases were changed considerably with the angle of incidence, while it was found to be largely independent of Reynolds number at 150. Characteristics of the vortex formation region and location of flow attachments, reattachments, and separations were observed by means of the flow visualizations. Depending on the inclination angle the effects of flow attachment, separation and reattachment on vortex-shedding phenomenon have been discussed.Keywords: Bluff body, vortex shedding, flow separation, flow reattachment
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 21152439 A Comparative CFD Study on the Hemodynamics of Flow through an Idealized Symmetric and Asymmetric Stenosed Arteries
Authors: B. Prashantha, S. Anish
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The aim of the present study is to computationally evaluate the hemodynamic factors which affect the formation of atherosclerosis and plaque rupture in the human artery. An increase of atherosclerosis disease in the artery causes geometry changes, which results in hemodynamic changes such as flow separation, reattachment, and adhesion of new cells (chemotactic) in the artery. Hence, geometry plays an important role in the determining the nature of hemodynamic patterns. Influence of stenosis in the non-bifurcating artery, under pulsatile flow condition, has been studied on an idealized geometry. Analysis of flow through symmetric and asymmetric stenosis in the artery revealed the significance of oscillating shear index (OSI), flow separation, low WSS zones and secondary flow patterns on plaque formation. The observed characteristic of flow in the post-stenotic region highlight the importance of plaque eccentricity on the formation of secondary stenosis on the arterial wall.
Keywords: Atherosclerotic plaque, Oscillatory Shear Index, Stenosis nature, Wall Shear Stress.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 15202438 On the Fixed Rainfall Intensity: Effects on Overland Flow Resistance, Shear Velocity and on Soil Erosion
Authors: L. Mouzai, M. Bouhadef
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Raindrops and overland flow both are erosive parameters but they do not act by the same way. The overland flow alone tends to shear the soil horizontally and concentrates into rills. In the presence of rain, the soil particles are removed from the soil surface in the form of a uniform sheet layer. In addition to this, raindrops falling on the flow roughen the water and soil surface depending on the flow depth, and retard the velocity, therefore influence shear velocity and Manning’s factor. To investigate this part, agricultural sandy soil, rainfall simulator and a laboratory soil tray of 0.2x1x3 m were the base of this work. Five overland flow depths of 0; 3.28; 4.28; 5.16; 5.60; 5.80 mm were generated under a rainfall intensity of 217.2 mm/h. Sediment concentration control is based on the proportionality of depth/microtopography. The soil loose is directly related to the presence of rain splash on thin sheet flow. The effect of shear velocity on sediment concentration is limited by the value of 5.28 cm/s. In addition to this, the rain splash reduces the soil roughness by breaking the soil crests. The rainfall intensity is the major factor influencing depth and soil erosion. In the presence of rainfall, the shear velocity of the flow is due to two simultaneous effects. The first, which is horizontal, comes from the flow and the second, vertical, is due to the raindrops.
Keywords: Flow resistance, laboratory experiments, rainfall simulator, sediment concentration, shear velocity, soil erosion.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 6072437 An Axisymmetric Finite Element Method for Compressible Swirling Flow
Authors: Raphael Zanella, Todd A. Oliver, Karl W. Schulz
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This work deals with the finite element approximation of axisymmetric compressible flows with swirl velocity. We are interested in problems where the flow, while weakly dependent on the azimuthal coordinate, may have a strong azimuthal velocity component. We describe the approximation of the compressible Navier-Stokes equations with H1-conformal spaces of axisymmetric functions. The weak formulation is implemented in a C++ solver with explicit time marching. The code is first verified with a convergence test on a manufactured solution. The verification is completed by comparing the numerical and analytical solutions in a Poiseuille flow case and a Taylor-Couette flow case. The code is finally applied to the problem of a swirling subsonic air flow in a plasma torch geometry.
Keywords: Axisymmetric problem, compressible Navier- Stokes equations, continuous finite elements, swirling flow.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3252436 A Meshfree Solution of Tow-Dimensional Potential Flow Problems
Authors: I. V. Singh, A. Singh
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In this paper, mesh-free element free Galerkin (EFG) method is extended to solve two-dimensional potential flow problems. Two ideal fluid flow problems (i.e. flow over a rigid cylinder and flow over a sphere) have been formulated using variational approach. Penalty and Lagrange multiplier techniques have been utilized for the enforcement of essential boundary conditions. Four point Gauss quadrature have been used for the integration on two-dimensional domain (Ω) and nodal integration scheme has been used to enforce the essential boundary conditions on the edges (┌). The results obtained by EFG method are compared with those obtained by finite element method. The effects of scaling and penalty parameters on EFG results have also been discussed in detail.
Keywords: Meshless, EFG method, potential flow, Lagrange multiplier method, penalty method, penalty parameter and scaling parameter
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 14882435 Salbutamol Sulphate-Ethylcellulose Tabletted Microcapsules: Pharmacokinetic Study using Convolution Approach
Authors: Ghulam Murtaza, Kalsoom Farzana
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The aim of this article is to narrate the utility of novel simulation approach i.e. convolution method to predict blood concentration of drug utilizing dissolution data of salbutamol sulphate microparticulate formulations with different release patterns (1:1, 1:2 and 1:3, drug:polymer). Dissolution apparatus II USP 2007 and 900 ml double distilled water stirrd at 50 rpm was employed for dissolution analysis. From dissolution data, blood drug concentration was determined, and in return predicted blood drug concentration data was used to calculate the pharmacokinetic parameters i.e. Cmax, Tmax, and AUC. Convolution is a good biwaiver technique; however its better utility needs it application in the conditions where biorelevant dissolution media are used.
Keywords: Convolution, Dissolution, Pharmacokinetics, Salbutamol sulphate
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 25802434 A Large-Eddy Simulation of Vortex Cell flow with Incoming Turbulent Boundary Layer
Authors: Arpiruk Hokpunna, Michael Manhart
Abstract:
We present a Large-Eddy simulation of a vortex cell with circular shaped. The results show that the flow field can be sub divided into four important zones, the shear layer above the cavity, the stagnation zone, the vortex core in the cavity and the boundary layer along the wall of the cavity. It is shown that the vortex core consits of solid body rotation without much turbulence activity. The vortex is mainly driven by high energy packets that are driven into the cavity from the stagnation point region and by entrainment of fluid from the cavity into the shear layer. The physics in the boundary layer along the cavity-s wall seems to be far from that of a canonical boundary layer which might be a crucial point for modelling this flow.Keywords: Turbulent flow, Large eddy simulations, boundary layer and cavity flow, vortex cell flow.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 82282433 Numerical Investigation of Improved Aerodynamic Performance of a NACA 0015 Airfoil Using Synthetic Jet
Authors: K. Boualem, T. Yahiaoui, A. Azzi
Abstract:
Numerical investigations are performed to analyze the flow behavior over NACA0015 and to evaluate the efficiency of synthetic jet as active control device. The second objective of this work is to investigate the influence of momentum coefficient of synthetic jet on the flow behaviour. The unsteady Reynolds-averaged Navier-Stokes equations of the turbulent flow are solved using, k-ω SST provided by ANSYS CFX-CFD code. The model presented in this paper is a comprehensive representation of the information found in the literature. Comparison of obtained numerical flow parameters with the experimental ones shows that the adopted computational procedure reflects nearly the real flow nature. Also, numerical results state that use of synthetic jets devices has positive effects on the flow separation, and thus, aerodynamic performance improvement of NACA0015 airfoil. It can also be observed that the use of synthetic jet increases the lift coefficient about 13.3% and reduces the drag coefficient about 52.7%.
Keywords: Active control, CFD, NACA airfoil, synthetic jet.
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