Search results for: hoop stress
427 Investigation on Fluid Flow Characteristics of the Orifice in Nuclear Power Plant
Authors: Nam-Seok Kim, Sang-Kyu Lee, Byung-Soo Shin, O-Hyun Keum
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The present paper represents a methodology for investigating flow characteristics near orifice plate by using a commercial computational fluid dynamics code. The flow characteristics near orifice plate which is located in the auxiliary feedwater system were modeled via three different levels of grid and four different types of Reynolds Averaged Navier-Stokes (RANS) equations with proper near-wall treatment. The results from CFD code were compared with experimental data in terms of differential pressure through the orifice plate. In this preliminary study, the Realizable k-ε and the Reynolds stress models with enhanced wall treatment were suitable to analyze flow characteristics near orifice plate, and the results had a good agreement with experimental data.Keywords: Auxiliary Feedwater, Computational Fluid Dynamics, Orifice, Nuclear Power Plant
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2479426 Elastic Strain-Concentration Factor of Cylindrical Bars with Circumferential Flat-Bottom Groove under Static Tension
Authors: Hitham M. Tlilan
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Using finite element method (FEM), the elastic new strain-concentration factor (SNCF) of cylindrical bars with circumferential flat-bottom groove is studied. This new SNCF has been defined under triaxial stress state. The employed specimens have constant groove depth with net section and gross diameters of 10.0 and 16.7 mm, respectively. The length of flatness ao has been varied form 0.0 ~12.5 mm to study the elastic SNCF of this type of geometrical irregularities. The results that the elastic new SNCF rapidly drops from its elastic value of the groove with ao = 0.0, i.e. circumferential U-notch, and reaches minimum value at ao = 2 mm. After that the elastic new SNCF becomes nearly constant with increasing flatness length (ao). The value of tensile load at yielding at the groove root increases with increasing ao. The current results show that severity of the notch decreases with increasing flatness length ao.Keywords: Bar, groove, strain, tension
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1666425 Modeling of Bio Scaffolds: Structural and Fluid Transport Characterization
Authors: Sahba Sadir, M. R. A. Kadir, A. Öchsner, M. N. Harun
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Scaffolds play a key role in tissue engineering and can be produced in many different ways depending on the applications and the materials used. Most researchers used an experimental trialand- error approach into new biomaterials but computer simulation applied to tissue engineering can offer a more exhaustive approach to test and screen out biomaterials. This paper develops the model of scaffolds and Computational Fluid Dynamics that show the value of computer simulations in determining the influence of the geometrical scaffold parameter porosity, pore size and shape on the permeability of scaffolds, magnitude of velocity, drop pressure, shear stress distribution and level and the proper design of the geometry of the scaffold. This creates a need for more advanced studies that include aspects of dynamic conditions of a micro fluid passing through the scaffold were characterized for tissue engineering applications and differentiation of tissues within scaffolds.
Keywords: Scaffold engineering, Tissue engineering, Cellularstructure, Biomaterial, Computational fluid dynamics.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2032424 Effect of T6 and Re-Aging Heat Treatment on Mechanical Properties of 7055 Aluminum Alloy
Authors: M. Esmailian, M. Shakouri, A. Mottahedi, S. G. Shabestari
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Heat treatable aluminum alloys such as 7075 and 7055, because of high strength and low density, are used widely in aircraft industry. For best mechanical properties, T6 heat treatment has recommended for this regards, but this temper treatment is sensitive to corrosion induced and Stress Corrosion Cracking (SCC) damage. For improving this property, the over-aging treatment (T7) applies to this alloy, but it decreases the mechanical properties up to 30 percent. Hence, to increase the mechanical properties, without any remarkable decrease in SCC resistant, Retrogression and Re-Aging (RRA) heat treatment is used. This treatment performs in a relatively short time. In this paper, the RRA heat treatment was applied to 7055 aluminum alloy and then effect of RRA time on the mechanical properties of 7055 has been investigated. The results show that the 40-minute time is suitable time for retrogression of 7055 aluminum alloy and ultimate strength increases up to 625MPa.Keywords: 7055 Aluminum alloy, Mechanical properties, SCC resistance, Heat Treatment.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3045423 Effect of Mode Loading on FCRG Plate with Double Through Crack at Hole
Authors: M. Benachour, N. Benachour, M. Benguediab, A. Hadjoui
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The knowledge of the nature of loading is very important in order to hold account on the total behavior such as vibration, shock, fatigue, etc. Fatigue present 90% of failure when loadings fatigues are very complex. In this paper a study of double through crack at hole for plate subjected to fatigue loading is presented. Various modes loading are studied where the applied load is the same one. The fatigue life is given where the effect of stress ratio is highlighted. This work is conducted on aluminum alloy 2024 T351 used for much aerospace and aeronautics applications. The fatigue crack growth behavior with constant amplitude is studied using the AFGROW code when Forman model is applied. The fatigue crack growth rate and fatigue life for different loading modes are compared with variation of others geometrical parameter such as thickness and dimensions of notch hole.Keywords: Fatigue crack, mode loading, aluminum alloy
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1543422 Substructure Method for Thermal-Stress Analysis of Liquid-Propellant Rocket Engine Combustion Chamber
Authors: Olga V. Korotkaya
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This article is devoted to an important problem of calculation of deflected mode of the combustion chamber and the nozzle end of a new liquid-propellant rocket cruise engine. A special attention is given to the methodology of calculation. Three operating modes are considered. The analysis has been conducted in ANSYS software. The methods of conducted research are mathematical modeling, substructure method, cyclic symmetry, finite element method. The calculation has been carried out to order of S.P. Korolev Rocket and Space Corporation «Energia». The main results are practical. Proposed methodology and created models would be able to use for a wide range of strength problems.
Keywords: Combustion chamber, cyclic symmetry, finite element method, liquid-propellant rocket engine, nozzle end, substructure.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3126421 Viscosity of Vegetable Oils and Biodiesel and Energy Generation
Authors: Thiago de O. Macedo, Roberto G. Pereira, Juan M. Pardal, Alexandre S. Soares, Valdir deJ. Lameira
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The present work describes an experimental investigation concerning the determination of viscosity behavior with shear rate and temperature of edible oils: canola; sunflower; corn; soybean and the no edible oil: Jatropha curcas. Besides these, it was tested a blend of canola, corn and sunflower oils as well as sunflower and soybean biodiesel. Based on experiments, it was obtained shear stress and viscosity at different shear rates of each sample at 40ºC, as well as viscosity of each sample at various temperatures in the range of 24 to 85ºC. Furthermore, it was compared the curves obtained for the viscosity versus temperature with the curves obtained by modeling the viscosity dependency on temperature using the Vogel equation. Also a test in a stationary engine was performed in order to study the energy generation using blends of soybean oil and soybean biodiesel with diesel.Keywords: Biofuel, energy generation, vegetable oil, viscosity.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 9585420 Effect of Mesh Size on the Supersonic Viscous Flow Parameters around an Axisymmetric Blunt Body
Authors: Rabah Haoui
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The aim of this work is to analyze a viscous flow around the axisymmetric blunt body taken into account the mesh size both in the free stream and into the boundary layer. The resolution of the Navier-Stokes equations is realized by using the finite volume method to determine the flow parameters and detached shock position. The numerical technique uses the Flux Vector Splitting method of Van Leer. Here, adequate time stepping parameter, CFL coefficient and mesh size level are selected to ensure numerical convergence. The effect of the mesh size is significant on the shear stress and velocity profile. The best solution is obtained with using a very fine grid. This study enabled us to confirm that the determination of boundary layer thickness can be obtained only if the size of the mesh is lower than a certain value limits given by our calculations.
Keywords: Supersonic flow, viscous flow, finite volume, blunt body.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2037419 Deterministic Modelling to Estimate Economic Impact from Implementation and Management of Large Infrastructure
Authors: Dimitrios J. Dimitriou
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It is widely recognised that the assets portfolio development is helping to enhance economic growth, productivity and competitiveness. While numerous studies and reports certify the positive effect of investments in large infrastructure investments on the local economy, still, the methodology to estimate the contribution in economic development is a challenging issue for researchers and economists. The key question is how to estimate those economic impacts in each economic system. This paper provides a compact and applicable methodological framework providing quantitative results in terms of the overall jobs and income generated into the project life cycle. According to a deterministic mathematical approach, the key variables and the modelling framework are presented. The numerical case study highlights key results for a new motorway project in Greece, which is experienced economic stress for many years, providing the opportunity for comparisons with similar cases.
Keywords: Quantitative modelling, economic impact; large transport infrastructure; economic assessment.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 872418 Dynamic Response of Wind Turbines to Theoretical 3D Seismic Motions Taking into Account the Rotational Component
Authors: L. Hermanns, M.A. Santoyo, L. E. Quirós, J. Vega, J. M. Gaspar-Escribano, B. Benito
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We study the dynamic response of a wind turbine structure subjected to theoretical seismic motions, taking into account the rotational component of ground shaking. Models are generated for a shallow moderate crustal earthquake in the Madrid Region (Spain). Synthetic translational and rotational time histories are computed using the Discrete Wavenumber Method, assuming a point source and a horizontal layered earth structure. These are used to analyze the dynamic response of a wind turbine, represented by a simple finite element model. Von Mises stress values at different heights of the tower are used to study the dynamical structural response to a set of synthetic ground motion time historiesKeywords: Synthetic seismograms, rotations, wind turbine, dynamic structural response
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1310417 Study of the Effect of Soil Compaction and Height on Pipe Ovality for Buried Steel Pipe
Authors: Ali Ghodsbin Jahromi, Ehsan Moradi
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In this paper, the numerical study of buried steel pipe in soil is investigated. Buried pipeline under soil weight, after embankment on the pipe leads to ovality of pipe. In this paper also it is considered the percentage of soil compaction, the soil height on the steel pipe and the external load of a mechanical excavator on the steel pipe and finally, the effect of these on the rate of pipe ovality investigated. Furthermore, the effect of the pipes’ thickness on ovality has been investigated. The results show that increasing the percentage of soil compaction has more effect on reducing percentage of ovality, and if the percentage of soil compaction increases, we can use the pipe with less thickness. Finally, ovality rate of the pipe and acceptance criteria of pipe diameter up to yield stress is investigated.
Keywords: Pipe ovality, soil compaction, finite element, pipe thickness.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 730416 Investigation of Tool Temperature and Surface Quality in Hot Machining of Hard-to-Cut Materials
Authors: M.Davami, M.Zadshakoyan
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Production of hard-to-cut materials with uncoated carbide cutting tools in turning, not only cause tool life reduction but also, impairs the product surface roughness. In this paper, influence of hot machining method were studied and presented in two cases. Case1-Workpiece surface roughness quality with constant cutting parameter and 300 ºC initial workpiece surface temperature. Case 2- Tool temperature variation when cutting with two speeds 78.5 (m/min) and 51 (m/min). The workpiece material and tool used in this study were AISI 1060 steel (45HRC) and uncoated carbide TNNM 120408-SP10(SANDVIK Coromant) respectively. A gas flam heating source was used to preheating of the workpiece surface up to 300 ºC, causing reduction of yield stress about 15%. Results obtained experimentally, show that the method used can considerably improved surface quality of the workpiece.
Keywords: Hard-to-cut material, Hot machining, Surfaceroughness, Tool Temperature
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2185415 One Typical Jacket Platform’s Reactions in Front of Sea Water Level Variations
Authors: M. A. Lotfollahi Yaghin, R. Rezaei
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Demanding structural safety under various loading conditions, has focused attention on their variation and structural elements behavior due to these variations. Jacket structures are designed for a specific water level (LAT). One of the important issues about these kinds of structures is the water level rise. For example, the level of water in the Caspian Sea has risen by 2.5m in the last fifteen years and is continuing to rise. In this paper, the structural behavior of one typical shallow or medium water jacket platform (a four-leg steel jacket platform in 55m water depth) under water level rise has been studied. The time history of Von Mises stress and nodal displacement has chosen for evaluating structural behavior. The results show that dependent on previous water depth and structural elements position; different structural elements have different behavior due to water level rise.
Keywords: Jacket offshore platform, Time- history, Von Mises, Water level rise, Utilization Ratio.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2410414 Hybrid Quasi-Steady Thermal Lattice Boltzmann Model for Studying the Behavior of Oil in Water Emulsions Used in Machining Tool Cooling and Lubrication
Authors: W. Hasan, H. Farhat, A. Alhilo, L. Tamimi
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Oil in water (O/W) emulsions are utilized extensively for cooling and lubricating cutting tools during parts machining. A robust Lattice Boltzmann (LBM) thermal-surfactants model, which provides a useful platform for exploring complex emulsions’ characteristics under variety of flow conditions, is used here for the study of the fluid behavior during conventional tools cooling. The transient thermal capabilities of the model are employed for simulating the effects of the flow conditions of O/W emulsions on the cooling of cutting tools. The model results show that the temperature outcome is slightly affected by reversing the direction of upper plate (workpiece). On the other hand, an important increase in effective viscosity is seen which supports better lubrication during the work.
Keywords: Hybrid lattice Boltzmann method, Gunstensen model, thermal, surfactant-covered droplet, Marangoni stress.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 771413 Using Music in the Classroom to Help Syrian Refugees Deal with Post-War Trauma
Authors: Vartan Agopian
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Millions of Syrian families have been displaced since the beginning of the Syrian war, and the negative effects of post-war trauma have shown detrimental effects on the mental health of refugee children. While educational strategies have focused on vocational training and academic achievement, little has been done to include music in the school curriculum to help these children improve their mental health. The literature of music education and psychology, on the other hand, shows the positive effects of music on traumatized children, especially when it comes to dealing with stress. This paper presents a brief literature review of trauma, music therapy, and music in the classroom, after having introduced the Syrian war and refugee situation. Furthermore, the paper highlights the benefits of using music with traumatized children from the literature and offers strategies for teachers (such as singing, playing an instrument, songwriting, and others) to include music in their classrooms to help Syrian refugee children deal with post-war trauma.
Keywords: Children, music, refugees, Syria, war.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1814412 Signal and Harmonic Analysis of a Compressor Blade for Identification of the Nonlinear Frequency Vibration
Authors: Farhad Asadi, Gholamhasan Payganeh
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High-speed turbomachine can experience significant centrifugal and gas bending loads. As a result, the compressor blades must be able to resist high-frequency oscillations due to surge or stall condition in flow field dynamics. In this paper, vibration characteristics of the 6th stage blade compressor have been examined in detail with, using 3-D finite element (FE) methods. The primary aim of this article is to gain an understanding of nonlinear vibration induced in the blade against different loading conditions. The results indicate the nonlinear behavior of the blade as a result of the amplitude of resonances or material properties. Since one of the leading causes of turbine blade failure is high cycle fatigue, simulations were started by specifying the stress distribution in the blade due to the centrifugal rotation. Next, resonant frequencies and critical speeds of the blade were defined by modal analysis. Finally, the harmonic analysis was simulated on the blades.
Keywords: Nonlinear vibration, modal analysis, resonance, frequency response, compressor blade.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 593411 Development and Optimization of Automated Dry-Wafer Separation
Authors: Tim Giesen, Christian Fischmann, Fabian Böttinger, Alexander Ehm, Alexander Verl
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In a state-of-the-art industrial production line of photovoltaic products the handling and automation processes are of particular importance and implication. While processing a fully functional crystalline solar cell an as-cut photovoltaic wafer is subject to numerous repeated handling steps. With respect to stronger requirements in productivity and decreasing rejections due to defects the mechanical stress on the thin wafers has to be reduced to a minimum as the fragility increases by decreasing wafer thicknesses. In relation to the increasing wafer fragility, researches at the Fraunhofer Institutes IPA and CSP showed a negative correlation between multiple handling processes and the wafer integrity. Recent work therefore focused on the analysis and optimization of the dry wafer stack separation process with compressed air. The achievement of a wafer sensitive process capability and a high production throughput rate is the basic motivation in this research.Keywords: Automation, Photovoltaic Manufacturing, Thin Wafer, Material Handling
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1661410 Patterns of Sports Supplement Use among Iranian Female Athletes
Authors: A. Golshanraz, L. Hakemi, L. Pourkazemi, E. Dadgostar, F. Moradzandi, R. Tabatabaee, F. Moradi, K. Hosseinihajiagha, N. Jazayeri, H. Abedifar, R. Fouladi, M. Khooban, H. Saboori, M. Kiani, M. Sajedi, E. Karooninejad, S.Moeen, M.Ghavam, F.Beiranvand, S.Mansoori, F.Gheisari, H.Barzegari
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Supplement use is common in athletes. Besides their cost, they may have side effects on health and performance. 250 questionnaires were distributed among female athletes (mean age 27.08 years). The questionnaire aimed to explore the frequency, type, believes, attitudes and knowledge regarding dietary supplements. Knowledge was good in 30.3%, fair in 60.2%, and poor in 9.1% of respondents. 65.3% of athletes did not use supplements regularly. The most widely used supplements were vitamins (48.4%), minerals (42.9%), energy supplements (21.3%), and herbals (20.9%). 68.9% of athletes believed in their efficacy. 34.4% experienced performance enhancement and 6.8% of reported side effects. 68.2% reported little knowledge and 60.9% were eager to learn more. In conclusion, many of the female athletes believe in the efficacy of supplements and think they are an unavoidable part of competitive sports. However, their information is not sufficient. We have to stress on education, consulting sessions, and rational prescription.
Keywords: athlete, female, sports, supplement
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1739409 Rheodynamic Lubrication of a Rectangular Squeeze Film Bearing with an Exponential Curvature Variation using Bingham Lubricants
Authors: K. P. Vishwanath, A. Kandasamy
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The present work deals with analyses of the effects of bearing curvature and non-Newtonian characteristics on the load capacity of an exponential rectangular squeeze film bearing using Bingham fluids as lubricants. Bingham fluids are characterized by an yield value and hence the formation of a “rigid" core in the region between the plates is justified. The flow is confined to the region between the core and the plates. The shape of the core has been identified through numerical means. Further, numerical solutions for the pressure distribution and load carrying capacity of the bearing for various values of Bingham number and curvature parameter have been obtained. The effects of bearing curvature and non-Newtonian characteristics of the lubricant on the bearing performances have been discussed.Keywords: rheodynamic lubrication, yield stress, non-Newtonianfluid, Bingham fluid, exponential squeeze film.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1612408 Experimental Investigation and Constitutive Modeling of Volume Strain under Uniaxial Strain Rate Jump Test in HDPE
Authors: Rida B. Arieby, Hameed N. Hameed
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In this work, tensile tests on high density polyethylene have been carried out under various constant strain rate and strain rate jump tests. The dependency of the true stress and specially the variation of volume strain have been investigated, the volume strain due to the phenomena of damage was determined in real time during the tests by an optical extensometer called Videotraction. A modified constitutive equations, including strain rate and damage effects, are proposed, such a model is based on a non-equilibrium thermodynamic approach called (DNLR). The ability of the model to predict the complex nonlinear response of this polymer is examined by comparing the model simulation with the available experimental data, which demonstrate that this model can represent the deformation behavior of the polymer reasonably well.
Keywords: Strain rate jump tests, Volume Strain, High Density Polyethylene, Large strain, Thermodynamics approach.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2106407 Prediction of Tool and Nozzle Flow Behavior in Ultrasonic Machining Process
Authors: Vinod Kumar, Jatinder Kumar
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The use of hard and brittle material has become increasingly more extensive in recent years. Therefore processing of these materials for the parts fabrication has become a challenging problem. However, it is time-consuming to machine the hard brittle materials with the traditional metal-cutting technique that uses abrasive wheels. In addition, the tool would suffer excessive wear as well. However, if ultrasonic energy is applied to the machining process and coupled with the use of hard abrasive grits, hard and brittle materials can be effectively machined. Ultrasonic machining process is mostly used for the brittle materials. The present research work has developed models using finite element approach to predict the mechanical stresses sand strains produced in the tool during ultrasonic machining process. Also the flow behavior of abrasive slurry coming out of the nozzle has been studied for simulation using ANSYS CFX module. The different abrasives of different grit sizes have been used for the experimentation work.Keywords: Stress, MRR, Flow, Ultrasonic Machining
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2797406 Propagation of Viscous Waves and Activation Energy of Hydrocarbon Fluids
Authors: Ram N. Singh, Abraham K. George, Dawood N. Al-Namaani
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The Euler-s equation of motion is extended to include the viscosity stress tensor leading to the formulation of Navier– Stokes type equation. The latter is linearized and applied to investigate the rotational motion or vorticity in a viscous fluid. Relations for the velocity of viscous waves and attenuation parameter are obtained in terms of viscosity (μ) and the density (¤ü) of the fluid. μ and ¤ü are measured experimentally as a function of temperature for two different samples of light and heavy crude oil. These data facilitated to determine the activation energy, velocity of viscous wave and the attenuation parameter. Shear wave velocity in heavy oil is found to be much larger than the light oil, whereas the attenuation parameter in heavy oil is quite low in comparison to light one. The activation energy of heavy oil is three times larger than light oil.Keywords: Activation Energy, Attenuation, Crude Oil, Navier- Stokes Equation, Viscosity.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1978405 Application of Micro-continuum Approach in the Estimation of Snow Drift Density, Velocity and Mass Transport in Hilly Bound Cold Regions
Authors: Mahmoud Zarrini, R. N. Pralhad
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We estimate snow velocity and snow drift density on hilly terrain under the assumption that the drifting snow mass can be represented using a micro-continuum approach (i.e. using a nonclassical mechanics approach assuming a class of fluids for which basic equations of mass, momentum and energy have been derived). In our model, the theory of coupled stress fluids proposed by Stokes [1] has been employed for the computation of flow parameters. Analyses of bulk drift velocity, drift density, drift transport and mass transport of snow particles have been carried out and computations made, considering various parametric effects. Results are compared with those of classical mechanics (logarithmic wind profile). The results indicate that particle size affects the flow characteristics significantly.
Keywords: Snow velocity, snow drift density, mass transport of snow particles, snow avalanche.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1746404 Structural Basis of Resistance of Helicobacterpylori DnaK to Antimicrobial Peptide Pyrrhocoricin
Authors: Musammat F. Nahar, Anna Roujeinikova
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Bacterial molecular chaperone DnaK plays an essential role in protein folding, stress response and transmembrane targeting of proteins. DnaKs from many bacterial species, including Escherichia coli, Salmonella typhimurium and Haemophilus infleunzae are the molecular targets for the insect-derived antimicrobial peptide pyrrhocoricin. Pyrrhocoricin-like peptides bind in the substrate recognition tunnel. Despite the high degree of crossspecies sequence conservation in the substrate-binding tunnel, some bacteria are not sensitive to pyrrhocoricin. This work addresses the molecular mechanism of resistance of Helicobacter pylori DnaK to pyrrhocoricin. Homology modelling, structural and sequence analysis identify a single aminoacid substitution at the interface between the lid and the β-sandwich subdomains of the DnaK substrate-binding domain as the major determinant for its resistance.
Keywords: Helicobacter pylori, molecular chaperone DnaK, pyrrhocoricin, structural biology.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1737403 Simulation of 3D Flow using Numerical Model at Open-channel Confluences
Authors: R.Goudarzizadeh, S.H.Mousavi Jahromi, N.Hedayat
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This paper analytically investigates the 3D flow pattern at the confluences of two rectangular channels having 900 angles using Navier-Stokes equations based on Reynolds Stress Turbulence Model (RSM). The equations are solved by the Finite- Volume Method (FVM) and the flow is analyzed in terms of steadystate (single-phased) conditions. The Shumate experimental findings were used to test the validity of data. Comparison of the simulation model with the experimental ones indicated a close proximity between the flow patterns of the two sets. Effects of the discharge ratio on separation zone dimensions created in the main-channel downstream of the confluence indicated an inverse relation, where a decrease in discharge ratio, will entail an increase in the length and width of the separation zone. The study also found the model as a powerful analytical tool in the feasibility study of hydraulic engineering projects.Keywords: 900 confluence angle, flow separation zone, numerical modeling, turbulent flow.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1847402 The Biomechanical Properties of the Different Modalities of Surgically Corrected Coarctation of the Aorta in Neonates and Infants
Authors: Elina Ligere, Valts Ozolins, Lauris Smits, Normunds Sikora, Ivars Melderis, Laila Feldmane, Aris Lacis, Vladimir Kasyanov
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Biomechanical properties of infantile aorta in vitro in cases of different standard anastomoses: end-to-end (ETE), extended anastomosis end-to-end (EETE) and subclavian flap aortoplasty (SFA) used for surgical correction of coarctation were analyzed to detect the influence of the method on the biomechanics of infantile aorta and possible changes in haemodinamics. 10 specimens of native aorta, 3 specimens with ETE, 4 EEET and 3 SFA were investigated. The experiments showed a non-linear relationship between stress and strain in the infantile aorta, the modulus of elasticity of the aortic wall increased with the increase of inner pressure. In the case of anastomosis end-to-end the modulus was almost constant, relevant to the modulus of elasticity of the aorta with the inner pressure 100-120 mmHg. The anastomoses EETE and SFA showed elastic properties closer to native aorta, the stiffness of ETE did not change with the changes in inner pressure.Keywords: biomechanics, coarctation, mechanical properties, neonatal aorta
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1999401 Glutamate Dehydrogenase and the Changing Pattern of Excretory Ammonia and Urea in Heteropneustes fossilis
Authors: Shuvasish Roy Choudhury, Rita Mahanta, Aparajita Borkotoki
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Fishes, in general, follow ammonotelic mode of excretion. However, certain stress factors may provoke them to excrete urea. In the present study, the possible role of ureogenesis to avoid accumulation of toxic ammonia under water-restricted condition was tested in Heteropneustes fossilis. A total of hundred fishes were collected and sacrificed. Excretory urea and ammonia were estimated in the water of the aquarium and glutamate dehydrogenase acitivity was measured in the hepatic tissue. During the experimental period, excretory ammonia in Heteropneustes fossilis was found between 931% to 16% above the baseline ammonia and excretory urea was found between 112% to 898% above the baseline urea. A high degree of correlation with r (coefficient of correlation) above 0.9 is observed between excretory ammonia and urea in Heteropneustes fossilis. However, only a moderate degree of correlation is observed between the activity of glutamate dehydrogenase and excretory ammonia and urea.
Keywords: Ammonia, aquarium, glutamate dehydrogenase, urea, ureogenesis.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1761400 Advanced Pulse Width Modulation Techniques for Z Source Multi Level Inverter
Authors: B. M. Manjunatha, D. V. Ashok Kumar, M. Vijay Kumar
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This paper proposes five level diode clamped Z source Inverter. The existing PWM techniques used for ZSI are restricted for two level. The two level Z Source Inverter have high harmonic distortions which effects the performance of the grid connected PV system. To improve the performance of the system the number of voltage levels in the output waveform need to be increased. This paper presents comparative analysis of a five level diode clamped Z source Inverter with different carrier based Modified Pulse Width Modulation techniques. The parameters considered for comparison are output voltage, voltage gain, voltage stress across switch and total harmonic distortion when powered by same DC supply. Analytical results are verified using MATLAB.
Keywords: Diode Clamped, Pulse Width Modulation, total harmonic distortion, Z Source Inverter.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2350399 Behaviour of Masonry Wall Constructed using Interlocking Soil Cement Bricks
Authors: Ahmad Z., Othman S. Z., Md Yunus B., Mohamed A.
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According to the masonry standard the compressive strength is basically dependent on factors such as the mortar strength and the relative values of unit and mortar strength. However interlocking brick has none or less use of mortar. Therefore there is a need to investigate the behavior of masonry walls using interlocking bricks. In this study a series of tests have been conducted; physical properties and compressive strength of brick units and masonry walls were constructed from interlocking bricks and tested under constant vertical load at different eccentricities. The purpose of the experimental investigations is to obtain the force displacement curves, analyze the behavior of masonry walls. The results showed that the brick is categorized as common brick (BS 3921:1985) and severe weathering grade (ASTM C62). The maximum compressive stress of interlocking brick wall is 3.6 N/mm2 and fulfilled the requirement of standard for residential building.Keywords: Interlocking brick, soil-cement brick, masonry wall, compressive strength, eccentricities
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 6182398 Failure Mechanism in Fixed-Ended Reinforced Concrete Deep Beams under Cyclic Load
Authors: A. Aarabzadeh, R. Hizaji
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Reinforced Concrete (RC) deep beams are a special type of beams due to their geometry, boundary conditions, and behavior compared to ordinary shallow beams. For example, assumption of a linear strain-stress distribution in the cross section is not valid. Little study has been dedicated to fixed-end RC deep beams. Also, most experimental studies are carried out on simply supported deep beams. Regarding recent tendency for application of deep beams, possibility of using fixed-ended deep beams has been widely increased in structures. Therefore, it seems necessary to investigate the aforementioned structural element in more details. In addition to experimental investigation of a concrete deep beam under cyclic load, different failure mechanisms of fixed-ended deep beams under this type of loading have been evaluated in the present study. The results show that failure mechanisms of deep beams under cyclic loads are quite different from monotonic loads.
Keywords: Deep beam, cyclic load, reinforced concrete, fixed-ended.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1134