Search results for: Contrast%20Agent
298 Hand Vein Image Enhancement With Radon Like Features Descriptor
Authors: Randa Boukhris Trabelsi, Alima Damak Masmoudi, Dorra Sellami Masmoudi
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Nowadays, hand vein recognition has attracted more attentions in identification biometrics systems. Generally, hand vein image is acquired with low contrast and irregular illumination. Accordingly, if you have a good preprocessing of hand vein image, we can easy extracted the feature extraction even with simple binarization. In this paper, a proposed approach is processed to improve the quality of hand vein image. First, a brief survey on existing methods of enhancement is investigated. Then a Radon Like features method is applied to preprocessing hand vein image. Finally, experiments results show that the proposed method give the better effective and reliable in improving hand vein images.
Keywords: Hand Vein, Enhancement, Contrast, RLF, SDME
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2227297 Detecting Rat’s Kidney Inflammation Using Real Time Photoacoustic Tomography
Authors: M. Y. Lee, D. H. Shin, S. H. Park, W.C. Ham, S.K. Ko, C. G. Song
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Photoacoustic Tomography (PAT) is a promising medical imaging modality that combines optical imaging contrast with the spatial resolution of ultrasound imaging. It can also distinguish the changes in biological features. But, real-time PAT system should be confirmed due to photoacoustic effect for tissue. Thus, we have developed a real-time PAT system using a custom-developed data acquisition board and ultrasound linear probe. To evaluate performance of our system, phantom test was performed. As a result of those experiments, the system showed satisfactory performance and its usefulness has been confirmed. We monitored the degradation of inflammation which induced on the rat’s kidney using real-time PAT.
Keywords: Photoacoustic tomography, inflammation detection, rat, kidney, contrast agent, ultrasound.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1357296 Speckle Characterization in Laser Projector Display
Authors: Meifang Xu, Yunbo Shi, Guoxian Tang, Jun Liu, Xuyuan Chen
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Speckle phenomena results from when coherent radiation is reflected from a rough surface. Characterizing the speckle strongly depends on the measurement condition and experimental setup. In this paper we report the experimental results produced with different parameters in the setup. We investigated the factors which affects the speckle contrast, such as, F-number, gamma value and exposure time of the camera, rather than geometric factors like the distance between the projector lens to the screen, the viewing distance, etc. The measurement results show that the speckle contrast decreases by decreasing F-number, by increasing gamma value, and slightly affects by exposure time of the camera and the gain value of the camera.Keywords: Characterization, laser projector, speckle
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1995295 Detecting Subsurface Circular Objects from Low Contrast Noisy Images: Applications in Microscope Image Enhancement
Authors: Soham De, Nupur Biswas, Abhijit Sanyal, Pulak Ray, Alokmay Datta
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Particle detection in very noisy and low contrast images is an active field of research in image processing. In this article, a method is proposed for the efficient detection and sizing of subsurface spherical particles, which is used for the processing of softly fused Au nanoparticles. Transmission Electron Microscopy is used for imaging the nanoparticles, and the proposed algorithm has been tested with the two-dimensional projected TEM images obtained. Results are compared with the data obtained by transmission optical spectroscopy, as well as with conventional circular object detection algorithms.Keywords: Transmission Electron Microscopy, Circular Hough Transform, Au Nanoparticles, Median Filter, Laplacian Sharpening Filter, Canny Edge Detection
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2568294 A Perceptual Image Coding method of High Compression Rate
Authors: Fahmi Kammoun, Mohamed Salim Bouhlel
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In the framework of the image compression by Wavelet Transforms, we propose a perceptual method by incorporating Human Visual System (HVS) characteristics in the quantization stage. Indeed, human eyes haven-t an equal sensitivity across the frequency bandwidth. Therefore, the clarity of the reconstructed images can be improved by weighting the quantization according to the Contrast Sensitivity Function (CSF). The visual artifact at low bit rate is minimized. To evaluate our method, we use the Peak Signal to Noise Ratio (PSNR) and a new evaluating criteria witch takes into account visual criteria. The experimental results illustrate that our technique shows improvement on image quality at the same compression ratio.Keywords: Contrast Sensitivity Function, Human Visual System, Image compression, Wavelet transforms.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1864293 Blind Source Separation Using Modified Gaussian FastICA
Authors: V. K. Ananthashayana, Jyothirmayi M.
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This paper addresses the problem of source separation in images. We propose a FastICA algorithm employing a modified Gaussian contrast function for the Blind Source Separation. Experimental result shows that the proposed Modified Gaussian FastICA is effectively used for Blind Source Separation to obtain better quality images. In this paper, a comparative study has been made with other popular existing algorithms. The peak signal to noise ratio (PSNR) and improved signal to noise ratio (ISNR) are used as metrics for evaluating the quality of images. The ICA metric Amari error is also used to measure the quality of separation.Keywords: Amari error, Blind Source Separation, Contrast function, Gaussian function, Independent Component Analysis.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1731292 Sperm Identification Using Elliptic Model and Tail Detection
Authors: Vahid Reza Nafisi, Mohammad Hasan Moradi, Mohammad Hosain Nasr-Esfahani
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The conventional assessment of human semen is a highly subjective assessment, with considerable intra- and interlaboratory variability. Computer-Assisted Sperm Analysis (CASA) systems provide a rapid and automated assessment of the sperm characteristics, together with improved standardization and quality control. However, the outcome of CASA systems is sensitive to the method of experimentation. While conventional CASA systems use digital microscopes with phase-contrast accessories, producing higher contrast images, we have used raw semen samples (no staining materials) and a regular light microscope, with a digital camera directly attached to its eyepiece, to insure cost benefits and simple assembling of the system. However, since the accurate finding of sperms in the semen image is the first step in the examination and analysis of the semen, any error in this step can affect the outcome of the analysis. This article introduces and explains an algorithm for finding sperms in low contrast images: First, an image enhancement algorithm is applied to remove extra particles from the image. Then, the foreground particles (including sperms and round cells) are segmented form the background. Finally, based on certain features and criteria, sperms are separated from other cells.Keywords: Computer-Assisted Sperm Analysis (CASA), Sperm identification, Tail detection, Elliptic shape model.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1918291 A Low Complexity Frequency Offset Estimation for MB-OFDM based UWB Systems
Authors: Wang Xue, Liu Dan, Liu Ying, Wang Molin, Qian Zhihong
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A low-complexity, high-accurate frequency offset estimation for multi-band orthogonal frequency division multiplexing (MB-OFDM) based ultra-wide band systems is presented regarding different carrier frequency offsets, different channel frequency responses, different preamble patterns in different bands. Utilizing a half-cycle Constant Amplitude Zero Auto Correlation (CAZAC) sequence as the preamble sequence, the estimator with a semi-cross contrast scheme between two successive OFDM symbols is proposed. The CRLB and complexity of the proposed algorithm are derived. Compared to the reference estimators, the proposed method achieves significantly less complexity (about 50%) for all preamble patterns of the MB-OFDM systems. The CRLBs turn out to be of well performance.Keywords: CAZAC, Frequency Offset, Semi-cross Contrast, MB-OFDM, UWB
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1653290 Ultrasonic Echo Image Adaptive Watermarking Using the Just-Noticeable Difference Estimation
Authors: Amnach Khawne, Kazuhiko Hamamoto, Orachat Chitsobhuk
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Most of the image watermarking methods, using the properties of the human visual system (HVS), have been proposed in literature. The component of the visual threshold is usually related to either the spatial contrast sensitivity function (CSF) or the visual masking. Especially on the contrast masking, most methods have not mention to the effect near to the edge region. Since the HVS is sensitive what happens on the edge area. This paper proposes ultrasound image watermarking using the visual threshold corresponding to the HVS in which the coefficients in a DCT-block have been classified based on the texture, edge, and plain area. This classification method enables not only useful for imperceptibility when the watermark is insert into an image but also achievable a robustness of watermark detection. A comparison of the proposed method with other methods has been carried out which shown that the proposed method robusts to blockwise memoryless manipulations, and also robust against noise addition.
Keywords: Medical image watermarking, Human Visual System, Image Adaptive Watermark
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1592289 A Perceptually Optimized Wavelet Embedded Zero Tree Image Coder
Authors: A. Bajit, M. Nahid, A. Tamtaoui, E. H. Bouyakhf
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In this paper, we propose a Perceptually Optimized Embedded ZeroTree Image Coder (POEZIC) that introduces a perceptual weighting to wavelet transform coefficients prior to control SPIHT encoding algorithm in order to reach a targeted bit rate with a perceptual quality improvement with respect to the coding quality obtained using the SPIHT algorithm only. The paper also, introduces a new objective quality metric based on a Psychovisual model that integrates the properties of the HVS that plays an important role in our POEZIC quality assessment. Our POEZIC coder is based on a vision model that incorporates various masking effects of human visual system HVS perception. Thus, our coder weights the wavelet coefficients based on that model and attempts to increase the perceptual quality for a given bit rate and observation distance. The perceptual weights for all wavelet subbands are computed based on 1) luminance masking and Contrast masking, 2) the contrast sensitivity function CSF to achieve the perceptual decomposition weighting, 3) the Wavelet Error Sensitivity WES used to reduce the perceptual quantization errors. The new perceptually optimized codec has the same complexity as the original SPIHT techniques. However, the experiments results show that our coder demonstrates very good performance in terms of quality measurement.
Keywords: DWT, linear-phase 9/7 filter, 9/7 Wavelets Error Sensitivity WES, CSF implementation approaches, JND Just Noticeable Difference, Luminance masking, Contrast masking, standard SPIHT, Objective Quality Measure, Probability Score PS.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2041288 Multichannel Image Mosaicing of Stem Cells
Authors: Alessandro Bevilacqua, Alessandro Gherardi, Filippo Piccinini
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Image mosaicing techniques are usually employed to offer researchers a wider field of view of microscopic image of biological samples. a mosaic is commonly achieved using automated microscopes and often with one “color" channel, whether it refers to natural or fluorescent analysis. In this work we present a method to achieve three subsequent mosaics of the same part of a stem cell culture analyzed in phase contrast and in fluorescence, with a common non-automated inverted microscope. The mosaics obtained are then merged together to mark, in the original contrast phase images, nuclei and cytoplasm of the cells referring to a mosaic of the culture, rather than to single images. The experiments carried out prove the effectiveness of our approach with cultures of cells stained with calcein (green/cytoplasm and nuclei) and hoechst (blue/nuclei) probes.
Keywords: Microscopy, image mosaicing, fluorescence, stem cells.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1476287 A Perceptually Optimized Foveation Based Wavelet Embedded Zero Tree Image Coding
Authors: A. Bajit, M. Nahid, A. Tamtaoui, E. H. Bouyakhf
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In this paper, we propose a Perceptually Optimized Foveation based Embedded ZeroTree Image Coder (POEFIC) that introduces a perceptual weighting to wavelet coefficients prior to control SPIHT encoding algorithm in order to reach a targeted bit rate with a perceptual quality improvement with respect to a given bit rate a fixation point which determines the region of interest ROI. The paper also, introduces a new objective quality metric based on a Psychovisual model that integrates the properties of the HVS that plays an important role in our POEFIC quality assessment. Our POEFIC coder is based on a vision model that incorporates various masking effects of human visual system HVS perception. Thus, our coder weights the wavelet coefficients based on that model and attempts to increase the perceptual quality for a given bit rate and observation distance. The perceptual weights for all wavelet subbands are computed based on 1) foveation masking to remove or reduce considerable high frequencies from peripheral regions 2) luminance and Contrast masking, 3) the contrast sensitivity function CSF to achieve the perceptual decomposition weighting. The new perceptually optimized codec has the same complexity as the original SPIHT techniques. However, the experiments results show that our coder demonstrates very good performance in terms of quality measurement.
Keywords: DWT, linear-phase 9/7 filter, Foveation Filtering, CSF implementation approaches, 9/7 Wavelet JND Thresholds and Wavelet Error Sensitivity WES, Luminance and Contrast masking, standard SPIHT, Objective Quality Measure, Probability Score PS.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1785286 Contrast-Enhanced Multispectal Upconversion Fluorescence Analysis for High-Resolution in-vivo Deep Tissue Imaging
Authors: Lijiang Wang, Wei Wang, Yuhong Xu
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Lanthanide-doped upconversion nanoparticles which can convert near-infrared lights to visible lights have attracted growing interest because of their great potentials in fluorescence imaging. Upconversion fluorescence imaging technique with excitation in the near-infrared (NIR) region has been used for imaging of biological cells and tissues. However, improving the detection sensitivity and decreasing the absorption and scattering in biological tissues are as yet unresolved problems. In this present study, a novel NIR-reflected multispectral imaging system was developed for upconversion fluorescent imaging in small animals. Based on this system, we have obtained the high contrast images without the autofluorescence when biocompatible UCPs were injected near the body surface or deeply into the tissue. Furthermore, we have extracted respective spectra of the upconversion fluorescence and relatively quantify the fluorescence intensity with the multispectral analysis. To our knowledge, this is the first time to analyze and quantify the upconversion fluorescence in the small animal imaging.
Keywords: Multispectral imaging, near-infrared, upconversion fluorescence imaging, upconversion nanoparticles.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1705285 Pre-Analysis of Printed Circuit Boards Based On Multispectral Imaging for Vision Based Recognition of Electronics Waste
Authors: Florian Kleber, Martin Kampel
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The increasing demand of gallium, indium and rare-earth elements for the production of electronics, e.g. solid state-lighting, photovoltaics, integrated circuits, and liquid crystal displays, will exceed the world-wide supply according to current forecasts. Recycling systems to reclaim these materials are not yet in place, which challenges the sustainability of these technologies. This paper proposes a multispectral imaging system as a basis for a vision based recognition system for valuable components of electronics waste. Multispectral images intend to enhance the contrast of images of printed circuit boards (single components, as well as labels) for further analysis, such as optical character recognition and entire printed circuit board recognition. The results show, that a higher contrast is achieved in the near infrared compared to ultraviolett and visible light.
Keywords: Electronic Waste, Recycling, Multispectral Imaging, Printed Circuit Boards, Rare-Earth Elements.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2672284 An Improved Illumination Normalization based on Anisotropic Smoothing for Face Recognition
Authors: Sanghoon Kim, Sun-Tae Chung, Souhwan Jung, Seongwon Cho
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Robust face recognition under various illumination environments is very difficult and needs to be accomplished for successful commercialization. In this paper, we propose an improved illumination normalization method for face recognition. Illumination normalization algorithm based on anisotropic smoothing is well known to be effective among illumination normalization methods but deteriorates the intensity contrast of the original image, and incurs less sharp edges. The proposed method in this paper improves the previous anisotropic smoothing-based illumination normalization method so that it increases the intensity contrast and enhances the edges while diminishing the effect of illumination variations. Due to the result of these improvements, face images preprocessed by the proposed illumination normalization method becomes to have more distinctive feature vectors (Gabor feature vectors) for face recognition. Through experiments of face recognition based on Gabor feature vector similarity, the effectiveness of the proposed illumination normalization method is verified.Keywords: Illumination Normalization, Face Recognition, Anisotropic smoothing, Gabor feature vector.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1538283 Contrast Enhancement in Digital Images Using an Adaptive Unsharp Masking Method
Authors: Z. Mortezaie, H. Hassanpour, S. Asadi Amiri
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Captured images may suffer from Gaussian blur due to poor lens focus or camera motion. Unsharp masking is a simple and effective technique to boost the image contrast and to improve digital images suffering from Gaussian blur. The technique is based on sharpening object edges by appending the scaled high-frequency components of the image to the original. The quality of the enhanced image is highly dependent on the characteristics of both the high-frequency components and the scaling/gain factor. Since the quality of an image may not be the same throughout, we propose an adaptive unsharp masking method in this paper. In this method, the gain factor is computed, considering the gradient variations, for individual pixels of the image. Subjective and objective image quality assessments are used to compare the performance of the proposed method both with the classic and the recently developed unsharp masking methods. The experimental results show that the proposed method has a better performance in comparison to the other existing methods.Keywords: Unsharp masking, blur image, sub-region gradient, image enhancement.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1395282 Enhancement of m-FISH Images using Spectral Unmixing
Authors: Martin De Biasio, Raimund Leitner, Franz G. Wuertz, Sergey Verzakov, Pierre J. Elbischger
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Breast carcinoma is the most common form of cancer in women. Multicolour fluorescent in-situ hybridisation (m-FISH) is a common method for staging breast carcinoma. The interpretation of m-FISH images is complicated due to two effects: (i) Spectral overlap in the emission spectra of fluorochrome marked DNA probes and (ii) tissue autofluorescence. In this paper hyper-spectral images of m-FISH samples are used and spectral unmixing is applied to produce false colour images with higher contrast and better information content than standard RGB images. The spectral unmixing is realised by combinations of: Orthogonal Projection Analysis (OPA), Alterating Least Squares (ALS), Simple-to-use Interactive Self-Modeling Mixture Analysis (SIMPLISMA) and VARIMAX. These are applied on the data to reduce tissue autofluorescence and resolve the spectral overlap in the emission spectra. The results show that spectral unmixing methods reduce the intensity caused by tissue autofluorescence by up to 78% and enhance image contrast by algorithmically reducing the overlap of the emission spectra.Keywords: breast carcinoma, hyperspectral imaging, m-FISH, spectral unmixing
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1758281 Performance of Compound Enhancement Algorithms on Dental Radiograph Images
Authors: S.A.Ahmad, M.N.Taib, N.E.A.Khalid, R.Ahmad, H.Taib
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The purpose of this research is to compare the original intra-oral digital dental radiograph images with images that are enhanced using a combination of image processing algorithms. Intraoral digital dental radiograph images are often noisy, blur edges and low in contrast. A combination of sharpening and enhancement method are used to overcome these problems. Three types of proposed compound algorithms used are Sharp Adaptive Histogram Equalization (SAHE), Sharp Median Adaptive Histogram Equalization (SMAHE) and Sharp Contrast adaptive histogram equalization (SCLAHE). This paper presents an initial study of the perception of six dentists on the details of abnormal pathologies and improvement of image quality in ten intra-oral radiographs. The research focus on the detection of only three types of pathology which is periapical radiolucency, widen periodontal ligament space and loss of lamina dura. The overall result shows that SCLAHE-s slightly improve the appearance of dental abnormalities- over the original image and also outperform the other two proposed compound algorithms.Keywords: intra-oral dental radiograph, histogram equalization, sharpening, CLAHE.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1773280 Enhanced Multi-Intensity Analysis in Multi-Scenery Classification-Based Macro and Micro Elements
Authors: R. Bremananth
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Several computationally challenging issues are encountered while classifying complex natural scenes. In this paper, we address the problems that are encountered in rotation invariance with multi-intensity analysis for multi-scene overlapping. In the present literature, various algorithms proposed techniques for multi-intensity analysis, but there are several restrictions in these algorithms while deploying them in multi-scene overlapping classifications. In order to resolve the problem of multi-scenery overlapping classifications, we present a framework that is based on macro and micro basis functions. This algorithm conquers the minimum classification false alarm while pigeonholing multi-scene overlapping. Furthermore, a quadrangle multi-intensity decay is invoked. Several parameters are utilized to analyze invariance for multi-scenery classifications such as rotation, classification, correlation, contrast, homogeneity, and energy. Benchmark datasets were collected for complex natural scenes and experimented for the framework. The results depict that the framework achieves a significant improvement on gray-level matrix of co-occurrence features for overlapping in diverse degree of orientations while pigeonholing multi-scene overlapping.Keywords: Automatic classification, contrast, homogeneity, invariant analysis, multi-scene analysis, overlapping.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1110279 An Image Enhancement Method Based on Curvelet Transform for CBCT-Images
Authors: Shahriar Farzam, Maryam Rastgarpour
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Image denoising plays extremely important role in digital image processing. Enhancement of clinical image research based on Curvelet has been developed rapidly in recent years. In this paper, we present a method for image contrast enhancement for cone beam CT (CBCT) images based on fast discrete curvelet transforms (FDCT) that work through Unequally Spaced Fast Fourier Transform (USFFT). These transforms return a table of Curvelet transform coefficients indexed by a scale parameter, an orientation and a spatial location. Accordingly, the coefficients obtained from FDCT-USFFT can be modified in order to enhance contrast in an image. Our proposed method first uses a two-dimensional mathematical transform, namely the FDCT through unequal-space fast Fourier transform on input image and then applies thresholding on coefficients of Curvelet to enhance the CBCT images. Consequently, applying unequal-space fast Fourier Transform leads to an accurate reconstruction of the image with high resolution. The experimental results indicate the performance of the proposed method is superior to the existing ones in terms of Peak Signal to Noise Ratio (PSNR) and Effective Measure of Enhancement (EME).
Keywords: Curvelet transform, image enhancement, CBCT, image denoising.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1249278 A New Image Psychovisual Coding Quality Measurement based Region of Interest
Authors: M. Nahid, A. Bajit, A. Tamtaoui, E. H. Bouyakhf
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To model the human visual system (HVS) in the region of interest, we propose a new objective metric evaluation adapted to wavelet foveation-based image compression quality measurement, which exploits a foveation setup filter implementation technique in the DWT domain, based especially on the point and region of fixation of the human eye. This model is then used to predict the visible divergences between an original and compressed image with respect to this region field and yields an adapted and local measure error by removing all peripheral errors. The technique, which we call foveation wavelet visible difference prediction (FWVDP), is demonstrated on a number of noisy images all of which have the same local peak signal to noise ratio (PSNR), but visibly different errors. We show that the FWVDP reliably predicts the fixation areas of interest where error is masked, due to high image contrast, and the areas where the error is visible, due to low image contrast. The paper also suggests ways in which the FWVDP can be used to determine a visually optimal quantization strategy for foveation-based wavelet coefficients and to produce a quantitative local measure of image quality.
Keywords: Human Visual System, Image Quality, ImageCompression, foveation wavelet, region of interest ROI.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1488277 Monitoring the Effect of Doxorubicin Liposomal in VX2 Tumor Using Magnetic Resonance Imaging
Authors: Ren-Jy Ben, Jo-Chi Jao, Chiu-Ya Liao, Ya-Ru Tsai, Lain-Chyr Hwang, Po-Chou Chen
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Cancer is still one of the serious diseases threatening the lives of human beings. How to have an early diagnosis and effective treatment for tumors is a very important issue. The animal carcinoma model can provide a simulation tool for the studies of pathogenesis, biological characteristics, and therapeutic effects. Recently, drug delivery systems have been rapidly developed to effectively improve the therapeutic effects. Liposome plays an increasingly important role in clinical diagnosis and therapy for delivering a pharmaceutic or contrast agent to the targeted sites. Liposome can be absorbed and excreted by the human body, and is well known that no harm to the human body. This study aimed to compare the therapeutic effects between encapsulated (doxorubicin liposomal, Lipodox) and un-encapsulated (doxorubicin, Dox) anti-tumor drugs using magnetic resonance imaging (MRI). Twenty-four New Zealand rabbits implanted with VX2 carcinoma at left thighs were classified into three groups: control group (untreated), Dox-treated group, and LipoDox-treated group, 8 rabbits for each group. MRI scans were performed three days after tumor implantation. A 1.5T GE Signa HDxt whole body MRI scanner with a high resolution knee coil was used in this study. After a 3-plane localizer scan was performed, three-dimensional (3D) fast spin echo (FSE) T2-weighted Images (T2WI) was used for tumor volumetric quantification. Afterwards, two-dimensional (2D) spoiled gradient recalled echo (SPGR) dynamic contrast-enhanced (DCE) MRI was used for tumor perfusion evaluation. DCE-MRI was designed to acquire four baseline images, followed by contrast agent Gd-DOTA injection through the ear vein of rabbit. A series of 32 images were acquired to observe the signals change over time in the tumor and muscle. The MRI scanning was scheduled on a weekly basis for a period of four weeks to observe the tumor progression longitudinally. The Dox and LipoDox treatments were prescribed 3 times in the first week immediately after the first MRI scan; i.e. 3 days after VX2 tumor implantation. ImageJ was used to quantitate tumor volume and time course signal enhancement on DCE images. The changes of tumor size showed that the growth of VX2 tumors was effectively inhibited for both LipoDox-treated and Dox-treated groups. Furthermore, the tumor volume of LipoDox-treated group was significantly lower than that of Dox-treated group, which implies that LipoDox has better therapeutic effect than Dox. The signal intensity of LipoDox-treated group is significantly lower than that of the other two groups, which implies that targeted therapeutic drug remained in the tumor tissue. This study provides a radiation-free and non-invasive MRI method for therapeutic monitoring of targeted liposome on an animal tumor model.Keywords: Doxorubicin, dynamic contrast-enhanced MRI, lipodox, magnetic resonance imaging, VX2 tumor model.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1979276 Iris Recognition Based On the Low Order Norms of Gradient Components
Authors: Iman A. Saad, Loay E. George
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Iris pattern is an important biological feature of human body; it becomes very hot topic in both research and practical applications. In this paper, an algorithm is proposed for iris recognition and a simple, efficient and fast method is introduced to extract a set of discriminatory features using first order gradient operator applied on grayscale images. The gradient based features are robust, up to certain extents, against the variations may occur in contrast or brightness of iris image samples; the variations are mostly occur due lightening differences and camera changes. At first, the iris region is located, after that it is remapped to a rectangular area of size 360x60 pixels. Also, a new method is proposed for detecting eyelash and eyelid points; it depends on making image statistical analysis, to mark the eyelash and eyelid as a noise points. In order to cover the features localization (variation), the rectangular iris image is partitioned into N overlapped sub-images (blocks); then from each block a set of different average directional gradient densities values is calculated to be used as texture features vector. The applied gradient operators are taken along the horizontal, vertical and diagonal directions. The low order norms of gradient components were used to establish the feature vector. Euclidean distance based classifier was used as a matching metric for determining the degree of similarity between the features vector extracted from the tested iris image and template features vectors stored in the database. Experimental tests were performed using 2639 iris images from CASIA V4-Interival database, the attained recognition accuracy has reached up to 99.92%.
Keywords: Iris recognition, contrast stretching, gradient features, texture features, Euclidean metric.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1956275 The Impact of Hospital Intensive Care Unit Window Design on Daylighting and Energy Performance in Desert Climate
Authors: A. Sherif, H. Sabry, A. Elzafarany, M. Gadelhak, R. Arafa, M. Aly
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This paper addresses the design of hospital Intensive Care Unit windows for the achievement of visual comfort and energy savings. The aim was to identify the window size and shading system configurations that could fulfill daylighting adequacy, avoid glare and reduce energy consumption. The study focused on addressing the effect of utilizing different shading systems in association with a range of Window-to-Wall Ratios (WWR) in different orientations under the desert clear-sky of Cairo, Egypt. The results of this study demonstrated that solar penetration is a critical concern affecting the design of ICU windows in desert locations, as in Cairo, Egypt. Use of shading systems was found to be essential in providing acceptable daylight performance and energy saving. Careful positioning of the ICU window towards a proper orientation can dramatically improve performance. It was observed that ICU windows facing the north direction enjoyed the widest range of successful window configuration possibilities at different WWRs. ICU windows facing south enjoyed a reasonable number of configuration options as well. By contrast, the ICU windows facing the east orientation had a very limited number of options that provide acceptable performance. These require additional local shading measures at certain times due to glare incidence. Moreover, use of horizontal sun breakers and solar screens to protect the ICU windows proved to be more successful than the other alternatives in a wide range of Window to Wall Ratios. By contrast, the use of light shelves and vertical shading devices seemed questionable.Keywords: Daylighting, Desert, Energy Efficiency, Shading.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2231274 Development of Effective Cooling Schemes of Gas Turbine Blades Based on Computer Simulation
Authors: Pasayev, A., C. Askerov, R. Sadiqov, C. Ardil
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In contrast to existing of calculation of temperature field of a profile part a blade with convective cooling which are not taking into account multi connective in a broad sense of this term, we develop mathematical models and highly effective combination (BIEM AND FDM) numerical methods from the point of view of a realization on the PC. The theoretical substantiation of these methods is proved by the appropriate theorems.
Keywords: multi coherent systems, method of the boundary integrated equations, singular operators, gas turbines
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1636273 Oxygen-Interstitials and Group-V Element Doping for p-Type ZnO
Authors: A. M. Gsiea, J. P. Goss, P. R. Briddon, K. M. Etmimi
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In realizing devices using ZnO, a key challenge is the production of p-type material. Substitution of oxygen by a group-V impurity is thought to result in deep acceptor levels, but a candidate made up from a complex of a group-V impurity (P, As, Sb) on a Zn site coupled with two vacant Zn sites is widely viewed as a candidate. We show using density-functional simulations that in contrast to such a view, complexes involving oxygen interstitials are energetically more favorable, resulting in group-V impurities coordinated with four, five or six oxygen atoms.Keywords: DFT, Oxygen, p-Type, ZnO.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2480272 Toward Indoor and Outdoor Surveillance Using an Improved Fast Background Subtraction Algorithm
Authors: A. El Harraj, N. Raissouni
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The detection of moving objects from a video image sequences is very important for object tracking, activity recognition, and behavior understanding in video surveillance. The most used approach for moving objects detection / tracking is background subtraction algorithms. Many approaches have been suggested for background subtraction. But, these are illumination change sensitive and the solutions proposed to bypass this problem are time consuming. In this paper, we propose a robust yet computationally efficient background subtraction approach and, mainly, focus on the ability to detect moving objects on dynamic scenes, for possible applications in complex and restricted access areas monitoring, where moving and motionless persons must be reliably detected. It consists of three main phases, establishing illumination changes invariance, background/foreground modeling and morphological analysis for noise removing. We handle illumination changes using Contrast Limited Histogram Equalization (CLAHE), which limits the intensity of each pixel to user determined maximum. Thus, it mitigates the degradation due to scene illumination changes and improves the visibility of the video signal. Initially, the background and foreground images are extracted from the video sequence. Then, the background and foreground images are separately enhanced by applying CLAHE. In order to form multi-modal backgrounds we model each channel of a pixel as a mixture of K Gaussians (K=5) using Gaussian Mixture Model (GMM). Finally, we post process the resulting binary foreground mask using morphological erosion and dilation transformations to remove possible noise. For experimental test, we used a standard dataset to challenge the efficiency and accuracy of the proposed method on a diverse set of dynamic scenes.
Keywords: Video surveillance, background subtraction, Contrast Limited Histogram Equalization, illumination invariance, object tracking, object detection, behavior understanding, dynamic scenes.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2077271 Making Computer Learn Color
Authors: Rinaldo Christian Tanumara, Ming Xie
Abstract:
Color categorization is shared among members in a society. This allows communication of color, especially when using natural language such as English. Hence sociable robot, to live coexist with human in human society, must also have the shared color categorization. To achieve this, many works have been done relying on modeling of human color perception and mathematical complexities. In contrast, in this work, the computer as brain of the robot learns color categorization through interaction with humans without much mathematical complexities.Keywords: Color categorization, color learning, machinelearning.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1429270 Thermoelectric Generators as Alternative Source for Electric Power
Authors: L. C. Ding, Bradley. G. Orr, K. Rahaoui, S. Truza, A. Date, A. Akbarzadeh
Abstract:
The research on thermoelectric has been a blooming field of research for the latest decade, owing to large amount of heat source available to be harvested, being eco-friendly and static in operation. This paper provides the performance of thermoelectric generator (TEG) with bulk material of bismuth telluride, Bi2Te3. Later, the performance of the TEGs is evaluated by considering attaching the TEGs on a plastic (polyethylene sheet) in contrast to the common method of attaching the TEGs on the metal surface.
Keywords: Electric power, heat transfer, renewable energy, thermoelectric generator.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1756269 An Implementation of Stipple Operations
Authors: Nakhoon Baek
Abstract:
Stipples are desired for pattern fillings and transparency effects. In contrast, some graphics standards, including OpenGL ES 1.1 and 2.0, omitted this feature. We represent details of providing line stipples and polygon stipples, through combining texture mapping and alpha blending functions. We start from the OpenGL-specified stipple-related API functions. The details of mathematical transformations are explained to get the correct texture coordinates. Then, the overall algorithm is represented, and its implementation results are followed. We accomplished both of line and polygon stipples, and verified its result with conformance test routines.Keywords: Stipple operation, OpenGL ES, Implementation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3062