Search results for: patient radiation dose.
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 995

Search results for: patient radiation dose.

515 High Energy Dual-Wavelength Mid-Infrared Extracavity KTA Optical Parametric Oscillator

Authors: Hongjun Liu, Qibing Sun, Nan Huang, Shaolan Zhu, Wei Zhao

Abstract:

A high energy dual-wavelength extracavity KTA optical parametric oscillator (OPO) with excellent stability and beam quality, which is pumped by a Q-switched single-longitudinal-mode Nd:YAG laser, has been demonstrated based on a type II noncritical phase matching (NCPM) KTA crystal. The maximum pulse energy of 10.2 mJ with the output stability of better than 4.1% rms at 3.467 μm is obtained at the repetition rate of 10 Hz and pulse width of 2 ns, and the 11.9 mJ of 1.535 μm radiation is obtained simultaneously. This extracavity NCPM KTA OPO is very useful when high energy, high beam quality and smooth time domain are needed.

Keywords: mid-infrared laser, OPO, dual-wavelength laser

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514 Study the Effect of Soft Errors on FlexRay-Based Automotive Systems

Authors: Yung-Yuan Chen, Kuen-Long Leu

Abstract:

FlexRay, as a communication protocol for automotive control systems, is developed to fulfill the increasing demand on the electronic control units for implementing systems with higher safety and more comfort. In this work, we study the impact of radiation-induced soft errors on FlexRay-based steer-by-wire system. We injected the soft errors into general purpose register set of FlexRay nodes to identify the most critical registers, the failure modes of the steer-by-wire system, and measure the probability distribution of failure modes when an error occurs in the register file.

Keywords: Soft errors, FlexRay, fault injection, steer-by-wirer

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513 Comparative Study of Two New Configurations of Solar Photovoltaic Thermal Collectors

Authors: K. Touafek, A. Khelifa, E. H. Khettaf, A. Embarek

Abstract:

Hybrid photovoltaic thermal (PV/T) solar system comprises a solar collector which is disposed on photovoltaic solar cells. The disadvantage of a conventional photovoltaic cell is that its performance decreases as the temperature increases. Indeed, part of the solar radiation is converted into electricity and is dissipated as heat, increasing the temperature of the photovoltaic cell with respect to the ambient temperature. The objective of this work is to study experimentally and implement a hybrid prototype to evaluate electrical and thermal performance. In this paper, an experimental study of two new configurations of hybrid collectors is exposed. The results are given and interpreted. The two configurations of absorber studied are a new combination with tubes and galvanized tank, the other is a tubes and sheet.

Keywords: Experimental, Photovoltaic, Solar, Temperature.

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512 A Retrospective Cross-Sectional Study on the Prevalence and Factors Associated with Virological Non-Suppression among HIV-Positive Adult Patients on Antiretroviral Therapy in Woliso Town, Oromia, Ethiopia

Authors: Teka Haile, Behailu Hawulte, Solomon Alemayehu

Abstract:

Background: HIV virological failure still remains a problem in HV/AIDS treatment and care. This study aimed to describe the prevalence and identify the factors associated with viral non-suppression among HIV-positive adult patients on antiretroviral therapy in Woliso Town, Oromia, Ethiopia. Methods: A retrospective cross-sectional study was conducted among 424 HIV-positive patient’s attending antiretroviral therapy (ART) in Woliso Town during the period from August 25, 2020 to August 30, 2020. Data collected from patient medical records were entered into Epi Info version 2.3.2.1 and exported to SPSS version 21.0 for analysis. Logistic regression analysis was done to identify factors associated with viral load non-suppression, and statistical significance of odds ratios were declared using 95% confidence interval and p-value < 0.05. Results: A total of 424 patients were included in this study. The mean age (± SD) of the study participants was 39.88 (± 9.995) years. The prevalence of HIV viral load non-suppression was 55 (13.0%) with 95% CI (9.9-16.5). Second-line ART treatment regimen (Adjusted Odds Ratio (AOR) = 8.98, 95% Confidence Interval (CI): 2.64, 30.58) and routine viral load testing (AOR = 0.01, 95% CI: 0.001, 0.02) were significantly associated with virological non-suppression. Conclusion: Virological non-suppression was high, which hinders the achievement of the third global 95 target. The second-line regimen and routine viral load testing were significantly associated with virological non-suppression. It suggests the need to assess the effectiveness of antiretroviral drugs for epidemic control. It also clearly shows the need to decentralize third-line ART treatment for those patients in need.

Keywords: Virological non-suppression, HIV-positive, ART, Woliso Town, Ethiopia.

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511 CAGE Questionnaire as a Screening Tool for Hazardous Drinking in an Acute Admissions Ward: Frequency of Application and Comparison with AUDIT-C Questionnaire

Authors: Ammar Ayad Issa Al-Rifaie, Zuhreya Muazu, Maysam Ali Abdulwahid, Dermot Gleeson

Abstract:

The aim of this audit was to examine the efficiency of alcohol history documentation and screening for hazardous drinkers at the Medical Admission Unit (MAU) of Northern General Hospital (NGH), Sheffield, to identify any potential for enhancing clinical practice. Data were collected from medical clerking sheets, ICE system and directly from 82 patients by three junior medical doctors using both CAGE questionnaire and AUDIT-C tool for newly admitted patients to MAU in NGH, in the period between January and March 2015. Alcohol consumption was documented in around two-third of the patient sample and this was documented fairly accurately by health care professionals. Some used subjective words such as 'social drinking' in the alcohol units’ section of the history. CAGE questionnaire was applied to only four patients and none of the patients had documented advice, education or referral to an alcohol liaison team. AUDIT-C tool had identified 30.4%, while CAGE 10.9%, of patients admitted to the NGH MAU as hazardous drinkers. The amount of alcohol the patient consumes positively correlated with the score of AUDIT-C (Pearson correlation 0.83). Re-audit is planned to be carried out after integrating AUDIT-C tool as labels in the notes and presenting a brief teaching session to junior doctors. Alcohol misuse screening is not adequately undertaken and no appropriate action is being offered to hazardous drinkers. CAGE questionnaire is poorly applied to patients and when satisfactory and adequately used has low sensitivity to detect hazardous drinkers in comparison with AUDIT-C tool. Re-audit of alcohol screening practice after introducing AUDIT-C tool in clerking sheets (as labels) is required to compare the findings and conclude the audit cycle.

Keywords: Alcohol screening, AUDIT-C, CAGE, Hazardous drinking.

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510 Gate Voltage Controlled Humidity Sensing Using MOSFET of VO2 Particles

Authors: A. A. Akande, B. P. Dhonge, B. W. Mwakikunga, A. G. J. Machatine

Abstract:

This article presents gate-voltage controlled humidity sensing performance of vanadium dioxide nanoparticles prepared from NH4VO3 precursor using microwave irradiation technique. The X-ray diffraction, transmission electron diffraction, and Raman analyses reveal the formation of VO2 (B) with V2O5 and an amorphous phase. The BET surface area is found to be 67.67 m2/g. The humidity sensing measurements using the patented lateral-gate MOSFET configuration was carried out. The results show the optimum response at 5 V up to 8 V of gate voltages for 10 to 80% of relative humidity. The dose-response equation reveals the enhanced resilience of the gated VO2 sensor which may saturate above 272% humidity. The response and recovery times are remarkably much faster (about 60 s) than in non-gated VO2 sensors which normally show response and recovery times of the order of 5 minutes (300 s).

Keywords: VO2, VO2 (B), V2O5, MOSFET, gate voltage, humidity sensor.

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509 Investigation on Choosing the Suitable Geometry of the Solar Air Heater to Certain Conditions

Authors: Abdulrahman M. Homadi

Abstract:

This study focuses on how to control the outlet temperature of a solar air heater in a way simpler than the existing methods. In this work, five cases have been studied by using ANSYS Fluent based on a CFD numerical method. All the cases have been simulated by utilizing the same criteria and conditions like the temperature, materials, areas except the geometry. The case studies are conducted in Little Rock (LR), AR, USA during the winter time supposedly on 15th of December. A fresh air that is flowing with a velocity of 0.5 m/s and a flow rate of 0.009 m3/s. The results prove the possibility of achieving a controlled temperature just by changing the geometric shape of the heater. This geometry guarantees that the absorber plate always has a normal component of the solar radiation at any time during the day. The heater has a sectarian shape with a radius of 150 mm where the outlet temperature remains almost constant for six hours.

Keywords: Solar energy, air heater, control of temperature, CFD.

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508 Software Architecture and Support for Patient Tracking Systems in Critical Scenarios

Authors: Gianluca Cornetta, Abdellah Touhafi, David J. Santos, Jose Manuel Vazquez

Abstract:

In this work a new platform for mobile-health systems is presented. System target application is providing decision support to rescue corps or military medical personnel in combat areas. Software architecture relies on a distributed client-server system that manages a wireless ad-hoc networks hierarchy in which several different types of client operate. Each client is characterized for different hardware and software requirements. Lower hierarchy levels rely in a network of completely custom devices that store clinical information and patient status and are designed to form an ad-hoc network operating in the 2.4 GHz ISM band and complying with the IEEE 802.15.4 standard (ZigBee). Medical personnel may interact with such devices, that are called MICs (Medical Information Carriers), by means of a PDA (Personal Digital Assistant) or a MDA (Medical Digital Assistant), and transmit the information stored in their local databases as well as issue a service request to the upper hierarchy levels by using IEEE 802.11 a/b/g standard (WiFi). The server acts as a repository that stores both medical evacuation forms and associated events (e.g., a teleconsulting request). All the actors participating in the diagnostic or evacuation process may access asynchronously to such repository and update its content or generate new events. The designed system pretends to optimise and improve information spreading and flow among all the system components with the aim of improving both diagnostic quality and evacuation process.

Keywords: IEEE 802.15.4 (ZigBee), IEEE 802.11 a/b/g (WiFi), distributed client-server systems, embedded databases, issue trackers, ad-hoc networks.

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507 Market Acceptance of Irradiated Food in the City of Piracicaba, Brazil

Authors: Vanessa de Cillos Silva, Fabrício José Piacente, Sônia Maria De Stefano Piedade, Valter Arthur

Abstract:

The increasing concern in relation to safety and hygiene of food consumption makes it so that food conservation is studied. Food radiation is a technique used for conservation, but many consumers associate this technique with dangers such as environmental contamination and development of diseases. This research had the objective of evaluating the acceptance of radiated products by the consumer market in the city of Piracicaba/SP-Brasil. The methodology adopted was the application of a questionnaire in the city’s supermarkets. After the application, the data was tabulated and analyzed. It was observed that the majority of interviewees would not eat irradiated food. The unfamiliarity and questions about the safety of irradiated food were the main causes of your rejection.

Keywords: Irradiation, market acceptance, questionnaire, storage.

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506 Mixed Convective Heat Transfer in Water-Based Al2O3 Nanofluid in Horizontal Rectangular Duct

Authors: Nur Irmawati, H.A. Mohammed

Abstract:

In the present study, mixed convection in a horizontal rectangular duct using Al2O3 is numerically investigated. The effects of different Rayleigh number, Reynolds number and radiation on flow and heat transfer characteristics are studied in detail. This study covers Rayleigh number in the range of 2 × 10^6 ≤ Ra ≤ 2 × 10^7 and Reynolds number in the range of 100 ≤ Re ≤ 1100. Results reveal that the Nusselt number increases as Reynolds and Rayleigh numbers increase. It is also found that the dimensionless temperature distribution increases as Rayleigh number increases.

Keywords: Numerical simulation, Mixed convection, Horizontal rectangular duct, Nanofluids.

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505 The Environmental Impact of Wireless Technologies in Nigeria: An Overview of the IoT and 5G Network

Authors: Powei Happiness Kerry

Abstract:

Introducing wireless technologies in Nigeria have improved the quality of lives of Nigerians, however, not everyone sees it in that light. The paper on the environmental impact of wireless technologies in Nigeria summarizes the scholarly views on the impact of wireless technologies on the environment, beaming its searchlight on 5G and internet of things in Nigeria while also exploring the theory of the Technology Acceptance Model (TAM). The study used a qualitative research method to gather important data from relevant sources and contextually draws inference from the derived data. The study concludes that the Federal Government of Nigeria, before agreeing to any latest development in the world of wireless technologies, should weigh the implications and deliberate extensively with all stalk holders putting into consideration the confirmation it will receive from the National Assembly.  

Keywords: IoT, 5G, ICT, electromagnetic radiation, wave, field, radiofrequency.

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504 The Concentration Analysis of CO2 Using ALOHA Code for Kuosheng Nuclear Power Plant

Authors: W. S. Hsu, Y. Chiang, H. C. Chen, J. R. Wang, S. W. Chen, J. H. Yang, C. Shih

Abstract:

Not only radiation materials, but also the normal chemical material stored in the power plant can cause a risk to the residents. In this research, the ALOHA code was used to perform the concentration analysis under the CO2 storage burst or leakage conditions for Kuosheng nuclear power plant (NPP). The Final Safety Analysis Report (FSAR) and data were used in this study. Additionally, the analysis results of ALOHA code were compared with the R.G. 1.78 failure criteria in order to confirm the control room habitability. The comparison results show that the ALOHA result for burst case was 0.923 g/m3 which was below the criteria. However, the ALOHA results for leakage case was 11.3 g/m3.

Keywords: BWR, ALOHA, habitability, Kuosheng.

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503 The Rail Traffic Management with Usage of C-OTDR Monitoring Systems

Authors: Andrey V. Timofeev, Dmitry V. Egorov, Viktor M. Denisov

Abstract:

This paper presents development results of usage of C-OTDR monitoring systems for rail traffic management. The COTDR method is based on vibrosensitive properties of optical fibers. Analysis of Rayleigh backscattering radiation parameters changes which take place due to microscopic seismoacoustic impacts on the optical fiber allows to determine seismoacoustic emission source positions and to identify their types. This approach proved successful for rail traffic management (moving block system, weigh- in-motion system etc.).

Keywords: C-OTDR systems, moving block-sections, rail traffic management, Rayleigh backscattering, weigh-in-motion.

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502 Effect of Polarization and Coherence of Optical Radiation on Sturgeon Sperm Motility

Authors: Nikolai V. Barulin, Vitaly Yu. Plavskii

Abstract:

This work contains information about the influence low-level optical irradiation on sperm motility of sturgeon fish. On the basis of given and earlier received data the following conclusion has been made. Among the photophysical processes of a resonant and not resonant nature (oriented action of light; action of gradient forces; dipole-dipole interaction; termooptical processes), which are capable to cause the photobiological effects depended on such laserspecific characteristics as polarization and coherency, determining influence belongs to oriented action of light and dipole-dipole interactions among the processes studied in the present work.

Keywords: sturgeon, aquaculture, fish sperm, laser, optical irradiation, sperm motility

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501 Speckle Characterization in Laser Projector Display

Authors: Meifang Xu, Yunbo Shi, Guoxian Tang, Jun Liu, Xuyuan Chen

Abstract:

Speckle phenomena results from when coherent radiation is reflected from a rough surface. Characterizing the speckle strongly depends on the measurement condition and experimental setup. In this paper we report the experimental results produced with different parameters in the setup. We investigated the factors which affects the speckle contrast, such as, F-number, gamma value and exposure time of the camera, rather than geometric factors like the distance between the projector lens to the screen, the viewing distance, etc. The measurement results show that the speckle contrast decreases by decreasing F-number, by increasing gamma value, and slightly affects by exposure time of the camera and the gain value of the camera.

Keywords: Characterization, laser projector, speckle

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500 Cannabidiol Treatment Ameliorates Acetaminophen-Induced Hepatotoxicity in Mice

Authors: Amr A. Fouad, Waleed H. Albuali, Iyad Jresat

Abstract:

The possible therapeutic effect of cannabidiol, the major non-psychotropic Cannabis constituent, was investigated against acute hepatotoxicity induced by a single oral dose of acetaminophen (500mg/kg) in mice. Cannabidiol (two intraperitoneal injections, 5mg/kg, each) was given 1 hour and 12 hours following acetaminophen administration. Acetaminophen administration caused significant elevations of serum alanine aminotransferase, and hepatic malondialdehyde, and nitric oxide levels, and a significant decrease in hepatic reduced glutathione. Cannabidiol significantly attenuated the deterioration in the measured biochemical parameters resulted from acetaminophen administration. Also, histopathological examination showed that cannabidiol markedly attenuated ameliorated acetaminophen-induced liver tissue damage. These results emphasize that cannabidiol represents a potential therapeutic option to protect against acetaminophen hepartotoxicity which is a common clinical problem.

Keywords: cannabidiol, acetaminophen, liver, mice.

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499 Possibilities of Sewage Sludge Application in the Conditions of Slovak Republic

Authors: Peter Takáč, Dana Šimová, Terézia Szabová, Tomáš Bakalár

Abstract:

The direct sewage sludge application is a relative cheap method for their liquidation. In the past heavy metal contents increase in soils treated with sewage sludge was observed. In 2003 there was acceptance on act n.188/2003 about sewage sludge application on soils. The basic philosophy of act is a safety of the environmental proof of sludge application on soils. The samples of soils from wastewater treatment plant (WTP) Poprad (35) and WTP Michalovce (33 samples) were analyzed which were chosen for sludge application on soils. According to the results only 14 areas for Poprad and 25 areas for Michalovce are suitable for sludge application according to act No. 188/2003. The application dose of sludge was calculated 50 t.ha-1 or 75 t. ha-1 once in 5 years to ensure that heavy metal contents in treated soils will be kept.

Keywords: Environmental safety, heavy metals in soils, sewagesludge application.

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498 Screening of Potential Sources of Tannin and Its Therapeutic Application

Authors: Mamta Kumari, Shashi Jain

Abstract:

Tannins are a unique category of plant phytochemicals especially in terms of their vast potential health-benefiting properties. Researchers have described the capacity of tannins to enhance glucose uptake and inhibit adipogenesis, thus being potential drugs for the treatment of non-insulin dependent diabetes mellitus. Thus, the present research was conducted to find out tannin content of food products. The percentage of tannin in various analyzed sources ranged from 0.0 to 108.53%; highest in kathaa and lowest in ker and mango bark. The percentage of tannins present in the plants, however, varies. Numerous studies have confirmed that the naturally occurring polyphenols are key factor for the beneficial effects of the herbal medicines. Isolation and identification of active constituents from plants, preparation of standardized dose & dosage regimen can play a significant role in improving the hypoglycaemic action.

Keywords: Tannins, Diabetes, Polyphenols, Antioxidants, Hypoglycemia.

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497 Steady State Temperature Distribution of Cast-Resin Dry Type Transformer Based on New Thermal Model Using Finite Element Method

Authors: Magdy B. Eteiba, Essam A. Alzahab, Yomna O. Shaker

Abstract:

In this paper, a thermal model of cast- resin dry type transformer is proposed. The proposed thermal model is solved by finite element technique to get the temperature at any location of the transformer. The basic modes of heat transfer such as conduction; convection and radiation are used to get the steady state temperature distribution of the transformer. The predicted temperatures are compared with experimental results reported in this paper and it is found a good agreement between them. The effects of various parameters such as width of air duct, ambient temperature and emissivity of the outer surface were also studied.

Keywords: Convection, dry type transformer, finite-elementtechnique, thermal model.

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496 Using Data Clustering in Oral Medicine

Authors: Fahad Shahbaz Khan, Rao Muhammad Anwer, Olof Torgersson

Abstract:

The vast amount of information hidden in huge databases has created tremendous interests in the field of data mining. This paper examines the possibility of using data clustering techniques in oral medicine to identify functional relationships between different attributes and classification of similar patient examinations. Commonly used data clustering algorithms have been reviewed and as a result several interesting results have been gathered.

Keywords: Oral Medicine, Cluto, Data Clustering, Data Mining.

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495 Some Aspects Regarding I. R. Absorbing Materials Based On Thin Alumina Films for Solar-Thermal Energy Conversion, Using X-Ray Diffraction Technique

Authors: Sorina Adriana Mitrea, Silvia Maria Hodorogea, Anca Duta, Luminita Isac, Elena Purghel, Mihaela Voinea

Abstract:

Solar energy is the most “available", ecological and clean energy. This energy can be used in active or passive mode. The active mode implies the transformation of solar energy into a useful energy. The solar energy can be transformed into thermal energy, using solar collectors. In these collectors, the active and the most important element is the absorber, material which performs the absorption of solar radiation and, in at the same time, limits its reflection. The paper presents some aspects regarding the IR absorbing material – a type of cermets, used as absorber in the solar collectors, by X Ray Diffraction Technique (XRD) characterization.

Keywords: Alumina films, solar energy, X-ray diffraction.

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494 Passive Cooling of Building by using Solar Chimney

Authors: Insaf Mehani, N. Settou

Abstract:

Natural ventilation is an important means to improve indoor thermal comfort and reduce the energy consumption. A solar chimney system is an enhancing natural draft device, which uses solar radiation to heat the air inside the chimney, thereby converting the thermal energy into kinetic energy. The present study considered some parameters such as chimney width and solar intensity, which were believed to have a significant effect on space ventilation. Fluent CFD software was used to predict buoyant air flow and flow rates in the cavities. The results were compared with available published experimental and theoretical data from the literature. There was an acceptable trend match between the present results and the published data for the room air change per hour, ACH. Further, it was noticed that the solar intensity has a more significant effect on ACH.

Keywords: Solar chimney, numerical simulation

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493 Apoptotic Induction Ability of Harmalol and Its Binding: Biochemical and Biophysical Perspectives

Authors: Kakali Bhadra

Abstract:

Harmalol administration caused remarkable reduction in proliferation of HepG2 cells with GI50 of 14.2 mM, without showing much cytotoxicity in embryonic liver cell line, WRL-68. Data from circular dichroism and differential scanning calorimetric analysis of harmalol-CT DNA complex shows conformational changes with prominent CD perturbation and stabilization of CT DNA by 8 oC. Binding constant and stoichiometry was also calculated using the above biophysical techniques. Further, dose dependent apoptotic induction ability of harmalol was studied in HepG2 cells using different biochemical assays. Generation of ROS, DNA damage, changes in cellular external and ultramorphology, alteration of membrane, formation of comet tail, decreased mitochondrial membrane potential and a significant increase in Sub Go/G1 population made the cancer cell, HepG2, prone to apoptosis. Up regulation of p53 and caspase 3 further indicated the apoptotic role of harmalol.

Keywords: Apoptosis, beta carboline alkaloid, comet assay, cytotoxicity, ROS.

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492 The Effectiveness of Mineral Fertilization of Winter Wheat by Nitrogen in the Soil and Climatic Conditions in the Cr

Authors: Václav Voltr, Jan Leština

Abstract:

The basis of examines is survey of 500 in the years 2002-2010, which was selected according to homogeneity of land cover and where 1090 revenues were evaluated. For achieved yields of winter wheat is obtained multicriterial regression function depending on the major factors influencing the consumption of nitrogen. The coefficient of discrimination of the established model is 0.722. The increase in efficiency of fertilization is involved in supply of organic nutrients, tillage, soil pH, past weather, the humus content in the subsoil and grain content to 0.001 mm. The decrease in efficiency was mainly influenced by the total dose of mineral nitrogen, although it was divided into multiple doses, the proportion loamy particles up to 0.01 mm, rainy, or conversely dry weather during the vegetation. The efficiency of nitrogen was found to be the smallest on undeveloped soils and the highest on chernozem and alluvial soils.

Keywords: Nitrogen efficiency, winter wheat, regression model

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491 Transient Heat Transfer Model for Car Body Primer Curing

Authors: D. Zabala, N. Sánchez, J. Pinto

Abstract:

A transient heat transfer mathematical model for the prediction of temperature distribution in the car body during primer baking has been developed by considering the thermal radiation and convection in the furnace chamber and transient heat conduction governing equations in the car framework. The car cockpit is considered like a structure with six flat plates, four vertical plates representing the car doors and the rear and front panels. The other two flat plates are the car roof and floor. The transient heat conduction in each flat plate is modeled by the lumped capacitance method. Comparison with the experimental data shows that the heat transfer model works well for the prediction of thermal behavior of the car body in the curing furnace, with deviations below 5%.

Keywords: Transient heat transfer, car body, lumpedcapacitance, primer baking.

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490 Evaluation of Aerodynamic Noise Generation by a Generic Side Mirror

Authors: Yiping Wang, Zhengqi Gu, Weiping Li, Xiaohui Lin

Abstract:

The aerodynamic noise radiation from a side view mirror (SVM) in the high-speed airflow is calculated by the combination of unsteady incompressible fluid flow analysis and acoustic analysis. The transient flow past the generic SVM is simulated with variable turbulence model, namely DES Detached Eddy Simulation and LES (Large Eddy Simulation). Detailed velocity vectors and contour plots of the time-varying velocity and pressure fields are presented along cut planes in the flow-field. Mean and transient pressure are also monitored at several points in the flow field and compared to corresponding experimentally data published in literature. The acoustic predictions made using the Ffowcs-Williams-Hawkins acoustic analogy (FW-H) and the boundary element (BEM).

Keywords: Aerodynamic noise, BEM, DES, FW-H acousticanalogy, LES

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489 Linear-Operator Formalism in the Analysis of Omega Planar Layered Waveguides

Authors: António L. Topa

Abstract:

A complete spectral representation for the electromagnetic field of planar multilayered waveguides inhomogeneously filled with omega media is presented. The problem of guided electromagnetic propagation is reduced to an eigenvalue equation related to a 2 ´ 2 matrix differential operator. Using the concept of adjoint waveguide, general bi-orthogonality relations for the hybrid modes (either from the discrete or from the continuous spectrum) are derived. For the special case of homogeneous layers the linear operator formalism is reduced to a simple 2 ´ 2 coupling matrix eigenvalue problem. Finally, as an example of application, the surface and the radiation modes of a grounded omega slab waveguide are analyzed.

Keywords: Metamaterials, linear operators, omega media, layered waveguide, orthogonality relations

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488 Vancomycin and Rifaximin Combination Therapy for Diarrhoea Predominant Irritable Bowel Syndrome: An Observational Study

Authors: P. Murphy, D. Vasic, A. W. Gunaratne, T. Tugonon, M. Ison, C. Pagonis, E. T. Sitchon, A. Le Busque, T. J. Borody

Abstract:

Irritable bowel syndrome (IBS) is a gastrointestinal disorder characterized by an alteration in bowel movements. There are three different types of IBS: diarrhea-predominant IBS (IBS-D), constipation-predominant IBS (IBS-C) and IBS with mixed bowel habit (IBS-M). Antimicrobials are increasingly being used as treatment for all types of IBS. Due to this increased use and subsequent success, the gut microbiome as a factor in the etiology of IBS is becoming more apparent. Accepted standard treatment has focused on IBS-C and involves either vancomycin or rifaximin. Here, we report on a cohort of 18 patients treated with both vancomycin and rifaximin for IBS-D. These patients’ records were reviewed retrospectively. In this cohort, patients were aged between 24-74 years (mean 44 years) and nine were female. At baseline all patients had diarrhea, four with mucus and one with blood. Other reported symptoms include abdominal pain (n = 11) bloating (n = 9), flatulence (n = 7), fatigue (n = 4) and nausea (n = 3). Patient’s treatments were personalized according to their symptom severity and tolerability and were treated with a combination of rifaximin (500-3000 mg/d) and vancomycin (500 mg-1500 mg/d) for an ongoing period. Follow-ups were conducted between 2-32 weeks. Of all patients, 89% reported improvement of at least 1 symptom, one reported no change and one patient’s symptoms got worse. The success of this combination treatment could be due to the different mechanisms of action undertaken by each medication. Vancomycin works by inhibiting the cell wall of the bacteria and rifaximin by inhibiting protein synthesis. This success in treatment validates the idea that IBS-D may be driven by a bacterial infection of the gastrointestinal microbiome. As IBS-D presents similarly to Clostridium difficile and symptom improvement can occur with the same treatment as Clostridium difficile of rifaximin and vancomycin, there is reason to suggest that the infectious agent could be an unidentified strain of Clostridium. Although these results offer some validity to the theory, more research is required.

Keywords: Clostridium difficile infection, diarrhea predominant irritable bowel syndrome, microbiome, vancomycin/rifaximin combination.

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487 Artificial Neural Network based Parameter Estimation and Design Optimization of Loop Antenna

Authors: Kumaresh Sarmah, Kandarpa Kumar Sarma

Abstract:

Artificial Neural Network (ANN)s are best suited for prediction and optimization problems. Trained ANNs have found wide spread acceptance in several antenna design systems. Four parameters namely antenna radiation resistance, loss resistance, efficiency, and inductance can be used to design an antenna layout though there are several other parameters available. An ANN can be trained to provide the best and worst case precisions of an antenna design problem defined by these four parameters. This work describes the use of an ANN to generate the four mentioned parameters for a loop antenna for the specified frequency range. It also provides insights to the prediction of best and worst-case design problems observed in applications and thereby formulate a model for physical layout design of a loop antenna.

Keywords: MLP, ANN, parameter, prediction, optimization.

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486 In vivo Introduced Extracellular Ubiquitin Regulates Intracellular Processes

Authors: Rusudan Sujashvili, Ekaterine Bakuradze, Irina Modebadze, Davit Dekanoidze

Abstract:

Extracellular ubiquitin in vivo effect on regenerative liver cells and liver histoarchitectonics has been studied. Experiments were performed on mature female white rats. Partial hepatectomy was made using the modified method of Higgins and Anderson. Standard histopathological assessment of liver tissue was used. Proliferative activity of hepatocytes was analyzed by colchicine mitotic index and immunohistochemical staining on ki67. We have found that regardless of number of injections and dose of extracellular ubiquitin liver histology has not been changed, so at tissue level no effect was observed. In vivo double injection of ubiquitin significantly decreases the mitotic activity at 32 hour point after partial hepatectomy. Thus, we can conclude that in vivo injected extracellular ubiquitin inhibits proliferative activity of hepatocytes in partially hepatectomyzed rats.

Keywords: Liver, regeneration, proliferation, ubiquitin.

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