Search results for: k-ω SST turbulence model
2991 Response Surface Methodology for Optimum Hardness of TiN on Steel Substrate
Authors: R. Joseph Raviselvan, K. Ramanathan, P. Perumal, M. R. Thansekhar
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Hard coatings are widely used in cutting and forming tool industries. Titanium Nitride (TiN) possesses good hardness, strength, and corrosion resistance. The coating properties are influenced by many process parameters. The coatings were deposited on steel substrate by changing the process parameters such as substrate temperature, nitrogen flow rate and target power in a D.C planer magnetron sputtering. The structure of coatings were analysed using XRD. The hardness of coatings was found using Micro hardness tester. From the experimental data, a regression model was developed and the optimum response was determined using Response Surface Methodology (RSM).Keywords: Hardness, RSM, sputtering, TiN XRD.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 15802990 Investigation of a Wearable Textile Monopole Antenna on Specific Absorption Rate at 2.45 GHz
Authors: Hasliza A. Rahim, Fareq Malek, Ismahayati Adam, Ahmad Sahadah, Nur B. M. Hashim, Nur A. M. Affendi, Azuwa Ali, Norshafinash Saudin, Latifah Mohamed
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This paper discusses the investigation of a wearable textile monopole antenna on specific absorption rate (SAR) for bodycentric wireless communication applications at 2.45 GHz. The antenna is characterized on a realistic 8 x 8 x 8 mm3 resolution truncated Hugo body model in CST Microwave Studio software. The result exhibited that the simulated SAR values were reduced significantly by 83.5% as the position of textile monopole was varying between 0 mm and 15 mm away from the human upper arm. A power absorption reduction of 52.2% was also noticed as the distance of textile monopole increased.Keywords: Monopole antenna, specific absorption rate, textile antenna.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 21272989 Threshold Submergence of Flow over PK Weirs
Authors: A. Javaheri, A. R. Kabiri-Samani
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In this study an extensive experimental research is carried out to develop a better understanding of the effects of Piano Key (PK) weir geometry on weir flow threshold submergence. Experiments were conducted in a 12 m long, 0.4 m wide and 0.7 m deep rectangular glass wall flume. The main objectives were to investigate the effect of the PK weir geometries including the weir length, weir height, inlet-outlet key widths, upstream and downstream apex overhangs, and slopped floors on threshold submergence and study the hydraulic flow characteristics. From the experimental results, a practical formula is proposed to evaluate the flow threshold submergence over PK weirs.Keywords: Model experimentation, flow characteristics, Piano Key weir, threshold submergence.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 21832988 Chinese Entrepreneurship in the Internet Age: Lessons from Alibaba.com
Authors: Linda Sau-ling LAI
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The story of Alibaba demonstrates a credible example of how a small start-up company can eventually make it big in the global economy through the Internet. This case study does not attempt to present Alibaba as a perfect formula; rather, it discusses the strategies carried out by the firm and, in the process, culls out the important lessons that can guide start-ups and aspiring entrepreneurs in the complex world of online trading. Similar to the interesting and exotic Asian cuisine that continuously evolves from the diversity of Asia-s people and their unique culture and personality, Alibaba has successfully transformed itself over the years, adapting to the changes in and demands of online businessto- business (B2B) commerce.
Keywords: Entrepreneurship, electronic commerce, leadership, business model, small and medium enterprises.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 71782987 Knowledge Acquisition, Absorptive Capacity, and Innovation Capability: An Empirical Study of Taiwan's Knowledge-Intensive Industries
Authors: Shu-Hsien. Liao, Chi-Chuan. Wu, Da-Chian. Hu, Guang An. Tsuei
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This study investigates the roles of knowledge acquisition, absorptive capacity, and innovation capability in finance and manufacturing industries. With 362 valid questionnaires from manufactures and financial industries in Taiwan, we examine the relationships between absorptive capacity, knowledge acquisition and innovation capability using a structural equation model. The results indicate that absorptive capacity is the mediator between knowledge acquisition and innovation capability, and that knowledge acquisition has a positive effect on absorptive capacity.Keywords: Absorptive capacity, knowledge acquisition, innovation capability.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 25362986 Description of Kinetics of Propane Fragmentation with a Support of Ab Initio Simulation
Authors: Amer Al Mahmoud Alsheikh, Jan Žídek, František Krčma
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Using ab initio theoretical calculations, we present analysis of fragmentation process. The analysis is performed in two steps. The first step is calculation of fragmentation energies by ab initio calculations. The second step is application of the energies to kinetic description of process. The energies of fragments are presented in this paper. The kinetics of fragmentation process can be described by numerical models. The method for kinetic analysis is described in this paper. The result - composition of fragmentation products - will be calculated in future. The results from model can be compared to the concentrations of fragments from mass spectrum.Keywords: Ab initio, Density functional theory, Fragmentation energy, Geometry optimization.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 18942985 A Numerical Study on Micromechanical Aspects in Short Fiber Composites
Authors: I. Ioannou, I. M. Gitman
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This study focused on the contribution of micro-mechanical parameters on the macro-mechanical response of short fiber composites, namely polypropylene matrix reinforced by glass fibers. In the framework of this paper, an attention has been given to the glass fibers length, as micromechanical parameter influences the overall macroscopic material’s behavior. Three dimensional numerical models were developed and analyzed through the concept of a Representative Volume Element (RVE). Results of the RVE-based approach were compared with analytical Halpin-Tsai’s model.
Keywords: Effective properties, representative volume element, short fiber reinforced composites.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 13872984 A Multi-Level Approach to Improve Sustainability Performances of Industrial Agglomerations
Authors: Patrick Innocenti, Elias Montini, Silvia Menato, Marzio Sorlini
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Documented experiences of industrial symbiosis are always triggered and driven only by economic goals: environmental and (even rarely) social results are sometimes assessed and declared as effects of virtuous behaviours, but are merely casual and un-pursued side externalities. Even worse: all the symbiotic project candidates entailing economic loss for just one of the (also dozen) partners are simply stopped without considering the overall benefit for the whole partnership. The here-presented approach aims at providing methodologies and tools to effectively manage these situations and fostering the implementation of virtuous symbiotic investments in manufacturing aggregations for a more sustainable production.
Keywords: Business model, industrial symbiosis, industrial agglomerations, sustainability.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 10092983 Properties of Rhizophora Charcoal for Product Design
Authors: Tanutpong Phriwanrat
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This research investigated the properties of Rhizophora charcoal for product design on 3 aspects: electrical conductor, impurity absorption, and fresh fruit shelf life. After the study, the properties of Rhizophora charcoal were applied to produce local product model at Ban Yisarn, Ampawa District, Samudsongkram Province which can add value to the Rhizophora charcoal as one of the OTOP (One-Tambon-One product). The results showed that the Rhizophora charcoal is not an electrical conductor but good liquid impurity absorber and it can extend fresh fruit shelf life.
Keywords: Design, Product design, Properties of Rhizophora, Rhizophora Charcoal.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 18652982 Two Kinds of Self-Oscillating Circuits Mechanically Demonstrated
Authors: Shiang-Hwua Yu, Po-Hsun Wu
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This study introduces two types of self-oscillating circuits that are frequently found in power electronics applications. Special effort is made to relate the circuits to the analogous mechanical systems of some important scientific inventions: Galileo’s pendulum clock and Coulomb’s friction model. A little touch of related history and philosophy of science will hopefully encourage curiosity, advance the understanding of self-oscillating systems and satisfy the aspiration of some students for scientific literacy. Finally, the two self-oscillating circuits are applied to design a simple class-D audio amplifier.
Keywords: Self-oscillation, sigma-delta modulator, pendulum clock, Coulomb friction, class-D amplifier.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 24562981 Variational Iteration Method for Solving Systems of Linear Delay Differential Equations
Authors: Sara Barati, Karim Ivaz
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In this paper, using a model transformation approach a system of linear delay differential equations (DDEs) with multiple delays is converted to a non-delayed initial value problem. The variational iteration method (VIM) is then applied to obtain the approximate analytical solutions. Numerical results are given for several examples involving scalar and second order systems. Comparisons with the classical fourth-order Runge-Kutta method (RK4) verify that this method is very effective and convenient.
Keywords: Variational iteration method, delay differential equations, multiple delays, Runge-Kutta method.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 24782980 Numerical Study for Structural Design of Composite Rotor with Crack Initiation
Authors: A. Chellil, A. Nour, S. Lecheb, H. Mechakra, A. Bouderba, H. Kebir
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In this paper, a coupled damage effect in the instability of a composite rotor is presented, under dynamic loading response in the harmonic analysis condition. The analysis of the stress which operates the rotor is done. Calculations of different energies and the virtual work of the aerodynamic loads from the rotor blade are developed. The use of the composite material for the rotor offers a good stability. Numerical calculations on the model developed prove that the damage effect has a negative effect on the stability of the rotor. The study of the composite rotor in transient system allowed determining the vibratory responses due to various excitations.
Keywords: Rotor, composite, damage, finite element, numerical.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 22502979 Transferring Route Plan over Time
Authors: Barıs Kocer, Ahmet Arslan
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Travelling salesman problem (TSP) is a combinational optimization problem and solution approaches have been applied many real world problems. Pure TSP assumes the cities to visit are fixed in time and thus solutions are created to find shortest path according to these point. But some of the points are canceled to visit in time. If the problem is not time crucial it is not important to determine new routing plan but if the points are changing rapidly and time is necessary do decide a new route plan a new approach should be applied in such cases. We developed a route plan transfer method based on transfer learning and we achieved high performance against determining a new model from scratch in every change.Keywords: genetic algorithms, transfer learning, travellingsalesman problem
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 12712978 Design of Laboratory Pilot Reactor for Filtering and Separation of Water – oil Emulsions
Authors: Irena Markovska, Nikolai Zaicev, Bogdan Bogdanov, Dimitar Georgiev, Yancho Hristov
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The present paper deals with problems related to the possibilities to use fractal systems to solve some important scientific and practical problems connected with filtering and separation of aqueous phases from organic ones. For this purpose a special separator have been designed. The reactor was filled with a porous material with fractal dimension, which is an integral part of the set for filtration and separation of emulsions. As a model emulsion hexadecan mixture with water in equal quantities (1:1) was used. We examined the hydrodynamics of the separation of the emulsion at different rates of submission of the entrance of the reactor.Keywords: pilot reactor, fractal systems, separation, emulsions
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 15952977 Scheduled Maintenance and Downtime Cost in Aircraft Maintenance Management
Authors: Remzi Saltoglu, Nazmia Humaira, Gokhan Inalhan
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During aircraft maintenance scheduling, operator calculates the budget of the maintenance. Usually, this calculation includes only the costs that are directly related to the maintenance process such as cost of labor, material, and equipment. In some cases, overhead cost is also included. However, in some of those, downtime cost is neglected claiming that grounding is a natural fact of maintenance; therefore, it is not considered as part of the analytical decision-making process. Based on the normalized data, we introduce downtime cost with its monetary value and add its seasonal character. We envision that the rest of the model, which works together with the downtime cost, could be checked with the real life cases, through the review of MRO cost and airline spending in the particular and scheduled maintenance events.
Keywords: Aircraft maintenance, downtime, downtime cost, maintenance cost.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 44242976 Ginzburg-Landau Model : an Amplitude Evolution Equation for Shallow Wake Flows
Authors: Imad Chaddad, Andrei A. Kolyshkin
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Linear and weakly nonlinear analysis of shallow wake flows is presented in the present paper. The evolution of the most unstable linear mode is described by the complex Ginzburg-Landau equation (CGLE). The coefficients of the CGLE are calculated numerically from the solution of the corresponding linear stability problem for a one-parametric family of shallow wake flows. It is shown that the coefficients of the CGLE are not so sensitive to the variation of the base flow profile.Keywords: Ginzburg-Landau equation, shallow wake flow, weakly nonlinear theory.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 15782975 Heat and Mass Transfer of an Oscillating Flow in a Porous Channel with Chemical Reaction
Authors: Z. Neffah, H. Kahalerras
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A numerical study is made in a parallel-plate porous channel subjected to an oscillating flow and an exothermic chemical reaction on its walls. The flow field in the porous region is modeled by the Darcy–Brinkman–Forchheimer model and the finite volume method is used to solve the governing equations. The effects of the modified Frank-Kamenetskii (FKm) and Damköhler (Dm) numbers, the amplitude of oscillation (A), and the Strouhal number (St) are examined. The main results show an increase of heat and mass transfer rates with A and St, and their decrease with FKm and Dm.Keywords: Chemical reaction, heat transfer, mass transfer, oscillating flow, porous channel.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20112974 Identifying the Best Global Solar Radiation Model for Hutat Suder, Saudi Arabia
Authors: H. Al-Sholigom, Z. Al-Mostafa
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Many associations and experimental models have been developed to estimate solar radiation around the world. The duration of sunshine is the most commonly used parameter for estimating global solar radiation because it can be easily and reliably measured. To estimate the global monthly solar average on horizontal surfaces, we used 52 models with widely available data in Hutat Suder, Saudi Arabia. After testing the models, some were not suitable for use in this area, while others differed in performance. The best models have been identified.
Keywords: Earth, Global solar radiation, Hutat Suder, Saudi Arabia, sunshine, measured data.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1272973 Ethnic Andean Concepts of Health and Illness in the Post-Colombian World and Its Relevance Today
Authors: Elizabeth J. Currie, Fernando Ortega Perez
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—‘MEDICINE’ is a new project funded under the EC Horizon 2020 Marie-Sklodowska Curie Actions, to determine concepts of health and healing from a culturally specific indigenous context, using a framework of interdisciplinary methods which integrates archaeological-historical, ethnographic and modern health sciences approaches. The study will generate new theoretical and methodological approaches to model how peoples survive and adapt their traditional belief systems in a context of alien cultural impacts. In the immediate wake of the conquest of Peru by invading Spanish armies and ideology, native Andeans responded by forming the Taki Onkoy millenarian movement, which rejected European philosophical and ontological teachings, claiming “you make us sick”. The study explores how people’s experience of their world and their health beliefs within it, is fundamentally shaped by their inherent beliefs about the nature of being and identity in relation to the wider cosmos. Cultural and health belief systems and related rituals or behaviors sustain a people’s sense of identity, wellbeing and integrity. In the event of dislocation and persecution these may change into devolved forms, which eventually inter-relate with ‘modern’ biomedical systems of health in as yet unidentified ways. The development of new conceptual frameworks that model this process will greatly expand our understanding of how people survive and adapt in response to cultural trauma. It will also demonstrate the continuing role, relevance and use of TM in present-day indigenous communities. Studies will first be made of relevant pre-Colombian material culture, and then of early colonial period ethnohistorical texts which document the health beliefs and ritual practices still employed by indigenous Andean societies at the advent of the 17th century Jesuit campaigns of persecution - ‘Extirpación de las Idolatrías’. Core beliefs drawn from these baseline studies will then be used to construct a questionnaire about current health beliefs and practices to be taken into the study population of indigenous Quechua peoples in the northern Andean region of Ecuador. Their current systems of knowledge and medicine have evolved within complex historical contexts of both the conquest by invading Inca armies in the late 15th century, followed a generation later by Spain, into new forms. A new model will be developed of contemporary Andean concepts of health, illness and healing demonstrating the way these have changed through time. With this, a ‘policy tool’ will be constructed as a bridhging facility into contemporary global scenarios relevant to other Indigenous, First Nations, and migrant peoples to provide a means through which their traditional health beliefs and current needs may be more appropriately understood and met. This paper presents findings from the first analytical phases of the work based upon the study of the literature and the archaeological records. The study offers a novel perspective and methods in the development policies sensitive to indigenous and minority people’s health needs.Keywords: Andean ethnomedicine, andean health beliefs, health beliefs models, traditional medicine.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 13092972 A study on a Generic Development Process for the BPM+SOA Design and Implementation
Authors: Toshimi Munehira
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In order to optimize annual IT spending and to reduce the complexity of an entire system architecture, SOA trials have been started. It is common knowledge that to design an SOA system we have to adopt the top-down approach, but in reality silo systems are being made, so these companies cannot reuse newly designed services, and cannot enjoy SOA-s economic benefits. To prevent this situation, we designed a generic SOA development process referred to as the architecture of “mass customization." To define the generic detail development processes, we did a case study on an imaginary company. Through the case study, we could define the practical development processes and found this could vastly reduce updating development costs.Keywords: SOA, BPM, Generic Model, MassCustomization
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 14562971 An Exploratory Approach of the Latin American Migrants’ Urban Space Transformation of Antofagasta City, Chile
Authors: Carolina Arriagada, Yasna Contreras
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Since mid-2000, the migratory flows of Latin American migrants to Chile have been increasing constantly. There are two reasons that would explain why Chile is presented as an attractive country for the migrants. On the one hand, traditional centres of migrants’ attraction such as the United States and Europe have begun to close their borders. On the other hand, Chile exhibits relative economic and political stability, which offers greater job opportunities and better standard of living when compared to the migrants’ origin country. At the same time, the neoliberal economic model of Chile, developed under an extractive production of the natural resources, has privatized the urban space. The market regulates the growth of the fragmented and segregated cities. Then, the vulnerable population, most of the time, is located in the periphery and in the marginal areas of the urban space. In this aspect, the migrants have begun to occupy those degraded and depressed areas of the city. The problem raised is that the increase of the social spatial segregation could be also attributed to the migrants´ occupation of the marginal urban places of the city. The aim of this investigation is to carry out an analysis of the migrants’ housing strategies, which are transforming the marginal areas of the city. The methodology focused on the urban experience of the migrants, through the observation of spatial practices, ways of living and networks configuration in order to transform the marginal territory. The techniques applied in this study are semi–structured interviews in-depth interviews. The study reveals that the migrants housing strategies for living in the marginal areas of the city are built on a paradox way. On the one hand, the migrants choose proximity to their place of origin, maintaining their identity and customs. On the other hand, the migrants choose proximity to their social and familiar places, generating sense of belonging. In conclusion, the migration as international displacements under a globalized economic model increasing socio spatial segregation in cities is evidenced, but the transformation of the marginal areas is a fundamental resource of their integration migratory process. The importance of this research is that it is everybody´s responsibility not only the right to live in a city without any discrimination but also to integrate the citizens within the social urban space of a city.
Keywords: Inhabit, migrations, social spatial segregation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 8892970 Feature Selection for Breast Cancer Diagnosis: A Case-Based Wrapper Approach
Authors: Mohammad Darzi, Ali AsgharLiaei, Mahdi Hosseini, HabibollahAsghari
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This article addresses feature selection for breast cancer diagnosis. The present process contains a wrapper approach based on Genetic Algorithm (GA) and case-based reasoning (CBR). GA is used for searching the problem space to find all of the possible subsets of features and CBR is employed to estimate the evaluation result of each subset. The results of experiment show that the proposed model is comparable to the other models on Wisconsin breast cancer (WDBC) dataset.Keywords: Case-based reasoning; Breast cancer diagnosis; Genetic algorithm; Wrapper feature selection
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 28752969 Performance Comparison of a Low Cost Air Quality Sensor with a Commercial Electronic Nose
Authors: Ünal Kızıl, Levent Genç, Sefa Aksu, Ahmet Tapınç
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The Figaro AM-1 sensor module which employs TGS 2600 model gas sensor in air quality assessment was used. The system was coupled with a microprocessor that enables sensor module to create warning message via telephone. This low cot sensor system’s performance was compared with a DiagNose II commercial electronic nose system. Both air quality sensor and electronic nose system employ metal oxide chemical gas sensors. In the study experimental setup, data acquisition methods for electronic nose system, and performance of the low cost air quality system were evaluated and explained.Keywords: Air quality, electronic nose, environmental quality, gas sensor.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 23862968 Integrate Communication Modeling into the Design Modeling at Early Stages of the Design Flow Case Study: Unmanned Aerial Vehicle (UAV)
Authors: Ibrahim A. Aref, Tarek A. El-Mihoub
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This paper shows how we can integrate communication modeling into the design modeling at early stages of the design flow. We consider effect of incorporating noise such as impulsive noise on system stability. We show that with change of the system model and investigate the system performance under the different communication effects. We modeled a unmanned aerial vehicle (UAV) as a demonstration using SystemC methodology. Moreover the system is modeled by joining the capabilities of UML and SystemC to operate at system level.Keywords: Modelling, SoC, SystemC, UAV, Simulation, SoC.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 22632967 Development of a Novel Low-Cost Flight Simulator for Pilot Training
Authors: Hongbin Gu, Dongsu Wu, Hui Liu
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A novel low-cost flight simulator with the development goals cost effectiveness and high performance has been realized for meeting the huge pilot training needs of airlines. The simulator consists of an aircraft dynamics model, a sophisticated designed low-profile electrical driven motion system with a subsided cabin, a mixed reality based semi-virtual cockpit system, a control loading system and some other subsystems. It shows its advantages over traditional flight simulator by its features achieved with open architecture, software solutions and low-cost hardware.Keywords: Flight simulator, mixed reality, motion system, control loading system.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 29402966 On the Perfomance of Multiband OFDM under Log-normal Channel Fading
Authors: N.M. Anas, S.K.S. Yusoff, R. Mohamad
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A modified Saleh-Valenzuela channel model has been adapted for Ultra Wideband (UWB) system. The suggested realistic channel is assessed by its distribution of fading amplitude and time of arrivals. Furthermore, the propagation characteristic has been distinct into four channel models, namely CM 1 to 4. Each are differentiate in terms of cluster arrival rates, rays arrival rate within each cluster and its respective constant decay rates. This paper described the multiband OFDM system performance simulates under these multipath conditions. Simulation work described in this paper is based on WiMedia ECMA-368 standard, which has been deployed for practical implementation of low cost and low power UWB devices.Keywords: Log-Normal, Multiband OFDM, Saleh-Valenzuela
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 17802965 Protein Delivery from Polymeric Nanoparticles
Authors: G. Spada, E. Gavini, P. Giunchedi
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Aim of this work was to compare the efficacy of two loading methods of proteins onto polymeric nanocarriers: adsorption and encapsulation methods. Preliminary studies of protein loading were done using Bovine Serum Albumin (BSA) as model protein. Nanocarriers were prepared starting from polylactic co-glycolic acid (PLGA) polymer; production methods used are two different variants of emulsion evaporation method. Nanoparticles obtained were analyzed in terms of dimensions by Dynamic Light Scattering and Loading Efficiency of BSA by Bradford Assay. Loaded nanoparticles were then submitted to in-vitro protein dissolution test in order to study the effect of the delivery system on the release rate of the protein.Keywords: Drug delivery, nanoparticles, PLGA, proteinadsorption, protein encapsulation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 25132964 A Relationship between Two Stabilizing Controllers and Its Application to Two-Stage Compensator Design without Coprime Factorizability – Single-Input Single-Output Case –
Authors: Kazuyoshi Mori
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In this paper, we first show a relationship between two stabilizing controllers, which presents an extended feedback system using two stabilizing controllers. Then, we apply this relationship to the two-stage compensator design. In this paper, we consider singleinput single-output plants. On the other hand, we do not assume the coprime factorizability of the model. Thus, the results of this paper are based on the factorization approach only, so that they can be applied to numerous linear systems.Keywords: Relationship among Compensators, Two-Stage Compensator Design, Parametrization of Stabilizing Controllers, Factorization Approach
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 12102963 Effects of Network Dynamics on Routing Efficiency in P2P Networks
Authors: Mojca Ciglaric, Andrej Krevl, Matjaž Pancur, Tone Vidmar
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P2P Networks are highly dynamic structures since their nodes – peer users keep joining and leaving continuously. In the paper, we study the effects of network change rates on query routing efficiency. First we describe some background and an abstract system model. The chosen routing technique makes use of cached metadata from previous answer messages and also employs a mechanism for broken path detection and metadata maintenance. Several metrics are used to show that the protocol behaves quite well even with high rate of node departures, but above a certain threshold it literally breaks down and exhibits considerable efficiency degradation.Keywords: Network dynamics, overlay network, P2P system, routing efficiency.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 13592962 Comparative Performance Analysis of Nonlinearity Cancellation Techniques for MOS-C Realization in Integrator Circuits
Authors: Hasan Çiçekli, Ahmet Gökçen, Uğur Çam
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In this paper, a comparative performance analysis of mostly used four nonlinearity cancellation techniques used to realize the passive resistor by MOS transistors, is presented. The comparison is done by using an integrator circuit which is employing sequentially Op-amp, OTRA and ICCII as active element. All of the circuits are implemented by MOS-C realization and simulated by PSPICE program using 0.35μm process TSMC MOSIS model parameters. With MOS-C realization, the circuits became electronically tunable and fully integrable which is very important in IC design. The output waveforms, frequency responses, THD analysis results and features of the nonlinearity cancellation techniques are also given.Keywords: Integrator circuits, MOS-C realization, nonlinearity cancellation, tunable resistors.
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