Search results for: Normal Tube
757 Gender Based Variability Time Series Complexity Analysis
Authors: Ramesh K. Sunkaria, Puneeta Marwaha
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Non linear methods of heart rate variability (HRV) analysis are becoming more popular. It has been observed that complexity measures quantify the regularity and uncertainty of cardiovascular RR-interval time series. In the present work, SampEn has been evaluated in healthy normal sinus rhythm (NSR) male and female subjects for different data lengths and tolerance level r. It is demonstrated that SampEn is small for higher values of tolerance r. Also SampEn value of healthy female group is higher than that of healthy male group for short data length and with increase in data length both groups overlap each other and it is difficult to distinguish them. The SampEn gives inaccurate results by assigning higher value to female group, because male subject have more complex HRV pattern than that of female subjects. Therefore, this traditional algorithm exhibits higher complexity for healthy female subjects than for healthy male subjects, which is misleading observation. This may be due to the fact that SampEn do not account for multiple time scales inherent in the physiologic time series and the hidden spatial and temporal fluctuations remains unexplored.
Keywords: Heart rate variability, normal sinus rhythm group, RR interval time series, sample entropy.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1770756 Influence of the Moisture Content on the Flowability of Fine-Grained Iron Ore Concentrate
Authors: C. Lanzerstorfer, M. Hinterberger
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The iron content of the ore used is crucial for the productivity and coke consumption rate in blast furnace pig iron production. Therefore, most iron ore deposits are processed in beneficiation plants to increase the iron content and remove impurities. In several comminution stages, the particle size of the ore is reduced to ensure that the iron oxides are physically liberated from the gangue. Subsequently, physical separation processes are applied to concentrate the iron ore. The fine-grained ore concentrates produced need to be transported, stored, and processed. For smooth operation of these processes, the flow properties of the material are crucial. The flowability of powders depends on several properties of the material: grain size, grain size distribution, grain shape, and moisture content of the material. The flowability of powders can be measured using ring shear testers. In this study, the influence of the moisture content on the flowability for the Krivoy Rog magnetite iron ore concentrate was investigated. Dry iron ore concentrate was mixed with varying amounts of water to produce samples with a moisture content in the range of 0.2 to 12.2%. The flowability of the samples was investigated using a Schulze ring shear tester. At all measured values of the normal stress (1.0 kPa – 20 kPa), the flowability decreased significantly from dry ore to a moisture content of approximately 3-5%. At higher moisture contents, the flowability was nearly constant, while at the maximum moisture content the flowability improved for high values of the normal stress only. The results also showed an improving flowability with increasing consolidation stress for all moisture content levels investigated. The wall friction angle of the dust with carbon steel (S235JR), and an ultra-high molecule low-pressure polyethylene (Robalon) was also investigated. The wall friction angle increased significantly from dry ore to a moisture content of approximately 3%. For higher moisture content levels, the wall friction angles were nearly constant. Generally, the wall friction angle was approximately 4° lower at the higher wall normal stress.
Keywords: Iron ore concentrate, flowability, moisture content, wall friction angle.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1522755 Differentiation of Cancerous Prostate tissue from Non-Cancerous Prostate tissue by using Elastic Light Single-Scattering Spectroscopy: A Feasibility Study
Authors: T. Denkçeken, M. Canpolat, Đ. Bassorgun, S. Yücel, M.A. Çiftçioğlu, M. Baykara Murat Canpolat , Tuba Denkçeken , Đbrahim Bassorgun , Selçuk Yücel , M. Akif Çiftçioğlu , Mehmet Baykara
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Elastic light single-scattering spectroscopy system with a single optical fiber probe was employed to differentiate cancerous prostate tissue from non-cancerous prostate tissue ex-vivo just after radical prostatectomy. First, ELSSS spectra were acquired from cancerous prostate tissue to define its spectral features. Then, spectra were acquired from normal prostate tissue to define difference in spectral features between the cancerous and normal prostate tissues. Of the total 66 tissue samples were evaluated from nine patients by ELSSS system. Comparing of histopathology results and ELSSS measurements revealed that sign of the spectral slopes of cancerous prostate tissue is negative and non-cancerous tissue is positive in the wavelength range from 450 to 750 nm. Based on the correlation between histopathology results and sign of the spectral slopes, ELSSS system differentiates cancerous prostate tissue from non- cancerous with a sensitivity of 0.95 and a specificity of 0.94.Keywords: Diagnosis, prostatic neoplasm, prostatectomy, spectrum analysis
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1524754 Deformation Characteristics of Fire Damaged and Rehabilitated Normal Strength Concrete Beams
Authors: Yeo Kyeong Lee, Hae Won Min, Ji Yeon Kang, Hee Sun Kim, Yeong Soo Shin
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In recent years, fire accidents have been steadily increased and the amount of property damage caused by the accidents has gradually raised. Damaging building structure, fire incidents bring about not only such property damage but also strength degradation and member deformation. As a result, the building structure undermines its structural ability. Examining the degradation and the deformation is very important because reusing the building is more economical than reconstruction. Therefore, engineers need to investigate the strength degradation and member deformation well, and make sure that they apply right rehabilitation methods. This study aims at evaluating deformation characteristics of fire damaged and rehabilitated normal strength concrete beams through both experiments and finite element analyses. For the experiments, control beams, fire damaged beams and rehabilitated beams are tested to examine deformation characteristics. Ten test beam specimens with compressive strength of 21MPa are fabricated and main test variables are selected as cover thickness of 40mm and 50mm and fire exposure time of 1 hour or 2 hours. After heating, fire damaged beams are air-recurred for 2 months and rehabilitated beams are repaired with polymeric cement mortar after being removed the fire damaged concrete cover. All beam specimens are tested under four points loading. FE analyses are executed to investigate the effects of main parameters applied to experimental study. Test results show that both maximum load and stiffness of the rehabilitated beams are higher than those of the fire damaged beams. In addition, predicted structural behaviors from the analyses also show good rehabilitation effect and the predicted load-deflection curves are similar to the experimental results. For the further, the proposed analytical method can be used to predict deformation characteristics of fire damaged and rehabilitated concrete beams without suffering from time and cost consuming of experimental process.Keywords: Fire, Normal strength concrete, Rehabilitation, Reinforced concrete beam.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2391753 Identification of Disease Causing DNA Motifs in Human DNA Using Clustering Approach
Authors: G. Tamilpavai, C. Vishnuppriya
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Studying DNA (deoxyribonucleic acid) sequence is useful in biological processes and it is applied in the fields such as diagnostic and forensic research. DNA is the hereditary information in human and almost all other organisms. It is passed to their generations. Earlier stage detection of defective DNA sequence may lead to many developments in the field of Bioinformatics. Nowadays various tedious techniques are used to identify defective DNA. The proposed work is to analyze and identify the cancer-causing DNA motif in a given sequence. Initially the human DNA sequence is separated as k-mers using k-mer separation rule. The separated k-mers are clustered using Self Organizing Map (SOM). Using Levenshtein distance measure, cancer associated DNA motif is identified from the k-mer clusters. Experimental results of this work indicate the presence or absence of cancer causing DNA motif. If the cancer associated DNA motif is found in DNA, it is declared as the cancer disease causing DNA sequence. Otherwise the input human DNA is declared as normal sequence. Finally, elapsed time is calculated for finding the presence of cancer causing DNA motif using clustering formation. It is compared with normal process of finding cancer causing DNA motif. Locating cancer associated motif is easier in cluster formation process than the other one. The proposed work will be an initiative aid for finding genetic disease related research.
Keywords: Bioinformatics, cancer motif, DNA, k-mers, Levenshtein distance, SOM.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1397752 Hydrodynamic Processes in Bubbly Liquid Flow in Tubes and Nozzles
Authors: Raisa Kh. Bolotnova, Marat N. Galimzianov, Andrey S. Topolnikov, Valeria A. Buzina, Uliana O. Agisheva
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The hydrodynamic processes in bubbly liquid flowing in tubes and nozzles are studied theoretically and numerically. The principal regularities of non-stationary processes of boiling liquid outflow are established under conditions of experiments when the depressurization of a tube with high pressure inside occurs. The steady-state solution of bubbly liquid flow in the nozzle of round cross section with high pressure and temperature conditions inside bubbles is studied accounting for phase transition and chemical reactions.Keywords: bubbly liquid, cavitation, chemical reactions, phase transition.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2046751 Designing a Framework for Network Security Protection
Authors: Eric P. Jiang
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As the Internet continues to grow at a rapid pace as the primary medium for communications and commerce and as telecommunication networks and systems continue to expand their global reach, digital information has become the most popular and important information resource and our dependence upon the underlying cyber infrastructure has been increasing significantly. Unfortunately, as our dependency has grown, so has the threat to the cyber infrastructure from spammers, attackers and criminal enterprises. In this paper, we propose a new machine learning based network intrusion detection framework for cyber security. The detection process of the framework consists of two stages: model construction and intrusion detection. In the model construction stage, a semi-supervised machine learning algorithm is applied to a collected set of network audit data to generate a profile of normal network behavior and in the intrusion detection stage, input network events are analyzed and compared with the patterns gathered in the profile, and some of them are then flagged as anomalies should these events are sufficiently far from the expected normal behavior. The proposed framework is particularly applicable to the situations where there is only a small amount of labeled network training data available, which is very typical in real world network environments.Keywords: classification, data analysis and mining, network intrusion detection, semi-supervised learning.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1797750 Electromagnetic Flow Meter Efficiency
Authors: Andrey D. Andreev, Ilona I. Iatcheva, Dimitar N. Karastoyanov, Rumena D. Stancheva
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A study of electromagnetic flow meter is presented in the paper. Comparison has been made between the analytical and the numerical results by the use of FEM numerical analysis (Quick Field 5.6) for determining polarization voltage through the circle cross section of the polarization transducer. Exciting and geometrical parameters increasing its effectiveness has been examined. The aim is to obtain maximal output signal. The investigations include different variants of the magnetic flux density distribution around the tube: homogeneous field of magnitude Bm, linear distribution with maximal value Bm and trapezium distribution conserving the same exciting magnetic energy as the homogeneous field.
Keywords: Effectiveness, electromagnetic flow meter, finite element method, polarization voltage.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2313749 Simulation of Surge Protection for a Direct Current Circuit
Authors: Pedro Luis Ferrer Penalver, Edmundo da Silva Braga
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In this paper, the performance of a simple surge protection for a direct current circuit was simulated. The protection circuit was developed from modified electric macro models of a gas discharge tube and a transient voltage suppressor diode. Moreover, a combination wave generator circuit was used as source of energy surges. The simulations showed that the circuit presented ensures immunity corresponding with test level IV of the IEC 61000-4-5:2014 international standard. The developed circuit can be modified to meet the requirements of any other equipment to be protected. Similarly, the parameters of the combination wave generator can be changed to provide different surge amplitudes.Keywords: Combination wave generator, IEC 61000-4-5, Pspice simulation, surge protection.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3327748 The Relation between Body Mass Index and Menstrual Cycle Disorders in Medical Students of University Pelita Harapan, Indonesia
Authors: Gabriella Tjondro, Julita Dortua Laurentina Nainggolan
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Introduction: There are several things affecting menstrual cycle, namely, nutritional status, diet, financial status of one’s household and exercises. The most commonly used parameter to calculate the fat in a human body is body mass index. Therefore, it is necessary to do research to prevent complications caused by menstrual disorder in the future. Design Study: This research is an observational analytical study with the cross-sectional-case control approach. Participants (n = 124; median age = 19.5 years ± SD 3.5) were classified into 2 groups: normal, NM (n = 62; BMI = 18-23 kg/m2) and obese, OB (n = 62; BMI = > 25 kg/m2). BMI was calculated from the equation; BMI = weight, kg/height, m2. Results: There were 79.10% from obese group who experienced menstrual cycle disorders (n=53, 79.10%; p value 0.00; OR 5.25) and 20.90% from normal BMI group with menstrual cycle disorders. There were several factors in this research that also influence the menstrual cycle disorders such as stress (44.78%; p value 0.00; OR 1.85), sleep disorders (25.37%; p value 0.00; OR 1.01), physical activities (25.37%; p value 0.00; OR 1.24) and diet (10.45%; p value 0.00; OR 1.07). Conclusion: There is a significant relation between body mass index (obese) and menstrual cycle disorders. However, BMI is not the only factor that affects the menstrual cycle disorders. There are several factors that also can affect menstrual cycle disorders, in this study we use stress, sleep disorders, physical activities and diet, in which none of them are dominant.
Keywords: Menstrual disorders, menstrual cycle, obesity, body mass index, stress, sleep disorders, physical activities, diet.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1268747 A Systems Approach to Gene Ranking from DNA Microarray Data of Cervical Cancer
Authors: Frank Emmert Streib, Matthias Dehmer, Jing Liu, Max Mühlhauser
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In this paper we present a method for gene ranking from DNA microarray data. More precisely, we calculate the correlation networks, which are unweighted and undirected graphs, from microarray data of cervical cancer whereas each network represents a tissue of a certain tumor stage and each node in the network represents a gene. From these networks we extract one tree for each gene by a local decomposition of the correlation network. The interpretation of a tree is that it represents the n-nearest neighbor genes on the n-th level of a tree, measured by the Dijkstra distance, and, hence, gives the local embedding of a gene within the correlation network. For the obtained trees we measure the pairwise similarity between trees rooted by the same gene from normal to cancerous tissues. This evaluates the modification of the tree topology due to progression of the tumor. Finally, we rank the obtained similarity values from all tissue comparisons and select the top ranked genes. For these genes the local neighborhood in the correlation networks changes most between normal and cancerous tissues. As a result we find that the top ranked genes are candidates suspected to be involved in tumor growth and, hence, indicates that our method captures essential information from the underlying DNA microarray data of cervical cancer.Keywords: Graph similarity, DNA microarray data, cancer.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1759746 Polymer Aerostatic Thrust Bearing under Circular Support for High Static Stiffness
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A new design of aerostatic thrust bearing is proposed for high static stiffness. The bearing body, which is mead of polymer covered with metallic membrane, is held by a circular ring. Such a support helps form a concave air gap to grasp the air pressure. The polymer body, which can be made rapidly by either injection or molding is able to provide extra damping under dynamic loading. The smooth membrane not only serves as the bearing surface but also protects the polymer body. The restrictor is a capillary inside a silicone tube. It can passively compensate the variation of load by expanding the capillary diameter for more air flux. In the present example, the stiffness soars from 15.85 N/μm of typical bearing to 349.85 N/μm at bearing elevation 9.5 μm; meanwhile the load capacity also enhances from 346.86 N to 704.18 N.Keywords: Aerostatic, bearing, polymer, static stiffness.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2090745 Time and Frequency Domain Analysis of Heart Rate Variability and their Correlations in Diabetes Mellitus
Authors: P. T. Ahamed Seyd, V. I. Thajudin Ahamed, Jeevamma Jacob, Paul Joseph K
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Diabetes mellitus (DM) is frequently characterized by autonomic nervous dysfunction. Analysis of heart rate variability (HRV) has become a popular noninvasive tool for assessing the activities of autonomic nervous system (ANS). In this paper, changes in ANS activity are quantified by means of frequency and time domain analysis of R-R interval variability. Electrocardiograms (ECG) of 16 patients suffering from DM and of 16 healthy volunteers were recorded. Frequency domain analysis of extracted normal to normal interval (NN interval) data indicates significant difference in very low frequency (VLF) power, low frequency (LF) power and high frequency (HF) power, between the DM patients and control group. Time domain measures, standard deviation of NN interval (SDNN), root mean square of successive NN interval differences (RMSSD), successive NN intervals differing more than 50 ms (NN50 Count), percentage value of NN50 count (pNN50), HRV triangular index and triangular interpolation of NN intervals (TINN) also show significant difference between the DM patients and control group.Keywords: Autonomic nervous system, diabetes mellitus, frequency domain and time domain analysis, heart rate variability.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3117744 A Study of Standing-Wave Thermoacoustic Refrigerator
Authors: Patcharin Saechan, Isares Dhuchakallaya
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Thermoacoustic refrigerator is a cooling device which uses the acoustic waves to produce the cooling effect. The aim of this paper is to explore the experimental and numerical feasibility of a standing-wave thermoacoustic refrigerator. The effects of the stack length, position of stack and operating frequency on the cooling performance are carried out. The circular pore stacks are tested under the atmospheric pressure. A low-cost loudspeaker is used as an acoustic driver. The results show that the location of stack installed in resonator tube has a greater effect on the cooling performance, than the stack length and operating frequency, respectively. The temperature difference across the ends of stack can be generated up to 13.7°C, and the temperature of cold-end is dropped down by 5.3°C from the ambient temperature.Keywords: Cooling performance, Refrigerator, Standing-wave, Thermoacoustics.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2362743 Increasing Directional Intensity of Output Light Beam from Photonic Crystal Slab Outlet Including Micro Cavity Resonators
Authors: A. Mobini, K. Saghafi, V. Ahmadi
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in this paper we modified a simple two-dimensional photonic crystal waveguide by creating micro cavity resonators in order to increase the output light emission which can be applicable to photonic integrated circuits. The micro cavity resonators are constructed by removing two tubes close to the waveguide output. Coupling emitted light from waveguide with those micro cavities, results increasing intensity of waveguide output light. Inserting a tube in last row of waveguide, we have improved directionality of output light beam.Keywords: photonic crystal, waveguide, micro cavity resonators, directional emission
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1325742 Shrinkage of High Strength Concrete
Authors: S.M. Gupta, V.K. Sehgal, S.K. Kaushik
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This paper presents the results of an experimental investigation carried out to evaluate the shrinkage of High Strength Concrete. High Strength Concrete is made by partially replacement of cement by flyash and silica fume. The shrinkage of High Strength Concrete has been studied using the different types of coarse and fine aggregates i.e. Sandstone and Granite of 12.5 mm size and Yamuna and Badarpur Sand. The Mix proportion of concrete is 1:0.8:2.2 with water cement ratio as 0.30. Superplasticizer dose @ of 2% by weight of cement is added to achieve the required degree of workability in terms of compaction factor. From the test results of the above investigation it can be concluded that the shrinkage strain of High Strength Concrete increases with age. The shrinkage strain of concrete with replacement of cement by 10% of Flyash and Silica fume respectively at various ages are more (6 to 10%) than the shrinkage strain of concrete without Flyash and Silica fume. The shrinkage strain of concrete with Badarpur sand as Fine aggregate at 90 days is slightly less (10%) than that of concrete with Yamuna Sand. Further, the shrinkage strain of concrete with Granite as Coarse aggregate at 90 days is slightly less (6 to 7%) than that of concrete with Sand stone as aggregate of same size. The shrinkage strain of High Strength Concrete is also compared with that of normal strength concrete. Test results show that the shrinkage strain of high strength concrete is less than that of normal strength concrete.Keywords: Shrinkage high strength concrete, fly ash, silica fume& superplastizers.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2530741 Recycled Waste Glass Powder as a Partial Cement Replacement in Polymer-Modified Mortars
Authors: Nikol Žižková
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The aim of this study was to observe the behavior of polymer-modified cement mortars with regard to the use of a pozzolanic admixture. Polymer-modified mortars (PMMs) containing various types of waste glass (waste packing glass and fluorescent tube glass) were produced always with 20% of cement substituted with a pozzolanic-active material. Ethylene/vinyl acetate copolymer (EVA) was used for polymeric modification. The findings confirm the possibility of using the waste glass examined herein as a partial substitute for cement in the production of PMM, which contributes to the preservation of non-renewable raw material resources and to the efficiency of waste glass material reuse.
Keywords: Recycled waste glass, polymer-modified mortars, pozzolanic admixture.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1259740 Simulation Study of Radial Heat and Mass Transfer Inside a Fixed Bed Catalytic Reactor
Authors: K. Vakhshouri, M.M. Y. Motamed Hashemi
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A rigorous two-dimensional model is developed for simulating the operation of a less-investigated type steam reformer having a considerably lower operating Reynolds number, higher tube diameter, and non-availability of extra steam in the feed compared with conventional steam reformers. Simulation results show that reasonable predictions can only be achieved when certain correlations for wall to fluid heat transfer equations are applied. Due to severe operating conditions, in all cases, strong radial temperature gradients inside the reformer tubes have been found. Furthermore, the results show how a certain catalyst loading profile will affect the operation of the reformer.
Keywords: Steam reforming, direct reduction, heat transfer, two-dimensional model, simulation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3647739 Spectrum Analysis with Monte Cralo Simulation, BEAMnrc, for Low Energy X-RAY
Authors: Z. Salehi Dehyagani, A. L. Yusoff
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BEAMnrc was used to calculate the spectrum and HVL for X-ray Beam during low energy X-ray radiation using tube model: SRO 33/100 /ROT 350 Philips. The results of BEAMnrc simulation and measurements were compared to the IPEM report number 78 and SpekCalc software. Three energies 127, 103 and 84 Kv were used. In these simulation a tungsten anode with 1.2 mm for Be window were used as source. HVLs were calculated from BEAMnrc spectrum with air Kerma method for four different filters. For BEAMnrc one billion particles were used as original particles for all simulations. The results show that for 127 kV, there was maximum 5.2 % difference between BEAMnrc and Measurements and minimum was 0.7% .the maximum 9.1% difference between BEAMnrc and IPEM and minimum was 2.3% .The maximum difference was 3.2% between BEAMnrc and SpekCal and minimum was 2.8%. The result show BEAMnrc was able to satisfactory predict the quantities of Low energy Beam as well as high energy X-ray radiation.Keywords: BEAMnr , Monte Carlo , HVL
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3055738 Control of Braking Force under Loaded and Empty Conditions on Two Wheeler
Authors: M. S. Manikandan, K. V. Nithish Kumar, M. Krishnamoorthi, V. Ganesh
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The Automobile Braking System has a crucial role for safety of the passenger and riding quality of the vehicle. The braking force mainly depends on normal reaction on the wheel and the co-efficient of friction between the tire and the road surface. Whenever a vehicle is loaded, the normal reaction on the rear wheel is increased. Thus the amount of braking force required to halt the vehicle with minimum stopping distance, is based on the pillion load on the vehicle. In this work, in order to vary the braking force in two wheelers, the mechanical leverage which operates the master cylinder is varied based on the pillion load. Thus the amount of braking force developed between ground and tire is varied. This optimum braking force on the disc brake helps in attaining the minimum vehicle stopping distance. In addition to that, it also helps in preventing sliding. Thus the system results in reducing the stopping distance of the two wheelers and providing a better braking efficiency than the conventional braking system.
Keywords: Braking force, Master cylinder, Mechanical leverage, Minimum stopping distance.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 6194737 Biological Diagnosis and Physiopathology of von Willebrand-s Disease in a Part of the Algerian Population in the East and the South
Authors: H. Djaara, M. Yahia, H. Bousselsela, N Khelif, A. Zidani, S. Benbia.
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Von Willebrand-s disease is the most common inherited bleeding disorder in humans, it caused by qualitative abnormalities of the von Willebrand factor (vWF). Our objective is to determine the prevalence of this disease at part of the Algerian population in the East and the South by a biological diagnosis based on specific biological tests (automated platelet count, the bleeding time (TS), the time of cephalin + activator (TCA), measure of the prothrombin rate (TP), vWF rate and factor VIII rate, Molecular electrophoresis of vWF multimers in agarose gel in the presence of SDS). Four patients of type III or severe Willebrand-s disease were found on 200 suspect cases. All cases are showed a deficit in vWF rate (< 5%), and factor VIII (P<0, 0001), and lengthening very significantly high of the TCA (P<0, 0001) and of the bleeding time (P<0,0001), with a normal blood platelet rate (P=0,7433) and a normal prothrombin rate (P=0,5808), an absence of all the multimers of vWF in plasma patients. The severe Willebrand-s disease is not only one pathology of primary haemostasis, but it can be accompanied by coagulation-s anomaly due to deficit in factor VIII. At this studied population, von Willebrand-s disease is less frequent (2%) than other hemorrhagic syndromes identified by the differential diagnosis like the thrombocytopenia (36%).Keywords: Von Willebrand's disease, differential diagnosis, von Willebrand factor, factor VIII, biological diagnosis, thrombocytopenia.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1740736 On The Analysis of a Compound Neural Network for Detecting Atrio Ventricular Heart Block (AVB) in an ECG Signal
Authors: Salama Meghriche, Amer Draa, Mohammed Boulemden
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Heart failure is the most common reason of death nowadays, but if the medical help is given directly, the patient-s life may be saved in many cases. Numerous heart diseases can be detected by means of analyzing electrocardiograms (ECG). Artificial Neural Networks (ANN) are computer-based expert systems that have proved to be useful in pattern recognition tasks. ANN can be used in different phases of the decision-making process, from classification to diagnostic procedures. This work concentrates on a review followed by a novel method. The purpose of the review is to assess the evidence of healthcare benefits involving the application of artificial neural networks to the clinical functions of diagnosis, prognosis and survival analysis, in ECG signals. The developed method is based on a compound neural network (CNN), to classify ECGs as normal or carrying an AtrioVentricular heart Block (AVB). This method uses three different feed forward multilayer neural networks. A single output unit encodes the probability of AVB occurrences. A value between 0 and 0.1 is the desired output for a normal ECG; a value between 0.1 and 1 would infer an occurrence of an AVB. The results show that this compound network has a good performance in detecting AVBs, with a sensitivity of 90.7% and a specificity of 86.05%. The accuracy value is 87.9%.Keywords: Artificial neural networks, Electrocardiogram(ECG), Feed forward multilayer neural network, Medical diagnosis, Pattern recognitionm, Signal processing.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2475735 Gene Expressions Associated with Ultrastructural Changes in Vascular Endothelium of Atherosclerotic Lesion
Authors: M. Maimunah, G.A. Froemming, H. Nawawi, M.I. Nafeeza, O. Effat, M.R. Rohayu Izanwati, M.S. Mohamed Saifulaman
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Attachment of the circulating monocytes to the endothelium is the earliest detectable events during formation of atherosclerosis. The adhesion molecules, chemokines and matrix proteases genes were identified to be expressed in atherogenesis. Expressions of these genes may influence structural integrity of the luminal endothelium. The aim of this study is to relate changes in the ultrastructural morphology of the aortic luminal surface and gene expressions of the endothelial surface, chemokine and MMP-12 in normal and hypercholesterolemic rabbits. Luminal endothelial surface from rabbit aortic tissue was examined by scanning electron microscopy (SEM) using low vacuum mode to ascertain ultrastructural changes in development of atherosclerotic lesion. Gene expression of adhesion molecules, MCP-1 and MMP-12 were studied by Real-time PCR. Ultrastructural observations of the aortic luminal surface exhibited changes from normal regular smooth intact endothelium to irregular luminal surface including marked globular appearance and ruptures of the membrane layer. Real-time PCR demonstrated differentially expressed of studied genes in atherosclerotic tissues. The appearance of ultrastructural changes in aortic tissue of hypercholesterolemic rabbits is suggested to have relation with underlying changes of endothelial surface molecules, chemokine and MMP-12 gene expressions.Keywords: Ultrastructure of luminal endothelial surface, Macrophage metalloelastase (MMP-12), Real-time PCR.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1556734 Investigation of Anti-diabetic and Hypocholesterolemic Potential of Psyllium Husk Fiber (Plantago psyllium) in Diabetic and Hypercholesterolemic Albino Rats
Authors: Ishtiaq Ahmed, Muhammad Naeem, Abdul Shakoor, Zaheer Ahmed, Hafiz Muhammad Nasir Iqbal
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The present study was conducted to observe the effect of Plantago psyllium on blood glucose and cholesterol levels in normal and alloxan induced diabetic rats. To investigate the effect of Plantago psyllium 40 rats were included in this study divided into four groups of ten rats in each group. One group A was normal, second group B was diabetic, third group C was non diabetic and hypercholesterolemic and fourth group D was diabetic and hypercholesterolemic. Two groups B and D were made diabetic by intraperitonial injection of alloxan dissolved in 1mL distilled water at a dose of 125mg/Kg of body weight. Two groups C and D were made hypercholesterolemic by oral administration of powder cholesterol (1g/Kg of body weight). The blood samples from all the rats were collected from coccygial vein on 1st day, then on 21st and 42nd day respectively. All the samples were analyzed for blood glucose and cholesterol level by using enzymatic kits. The blood glucose and cholesterol levels of treated groups of rats showed significant reduction after 7 weeks of treatment with Plantago psyllium. By statistical analysis of results it was found that Plantago psyllium has anti-diabetic and hypocholesterolemic activity in diabetic and hypercholesterolemic albino rats.Keywords: Albino rats, alloxan, Plantago psyllium, statistical analysis
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2170733 Quality Attributes of Various Spray Dried Pulp Powder Prepared from Low Temperature Stored Calcium Salts Pretreated Guava Fruits
Authors: Renu Rahel, A. S. Chauhan, K. Srinivasulu, R. Ravi, V. B. Kudachikar
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The effect of calcium salts on the storage stability and on the quality attributes of both fresh and processed product (guava powder) of white flesh guavas (var ‘Allahabad safeda’) was studied. The pulp behavioral studies of fully ripened guava fruits indicated that fruits pretreated with 3% and 4.5% calcium chloride had the least viscosity. The guava pulp powder using spray drying technique was developed and its storage stability and the moisture sorption studies were carried out for product quality evaluation at normal storage condition (27°C; 65%RH). Results revealed that powder obtained from 3% calcium chloride pretreated guavas was found to be at par with the powder obtained from control guavas after 90 days of normal storage. Studies on microbiological quality of guava pulp powder indicated that among the treatments powder obtained from guava fruit pretreated with 3% calcium chloride to be the most effective through restricting microbial counts of total plate count, yeast, mold, Staphylococcus and E. coli below their permissible limit. Moisture sorption studies of guava powder revealed that foil laminate 12μm PET/9 μm foil/38-40 μm is the most suitable packaging material recommended.Keywords: White flesh guava, calcium salts, spray drying, powder, storage stability.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2065732 Development of Genetic-based Machine Learning for Network Intrusion Detection (GBML-NID)
Authors: Wafa' S.Al-Sharafat, Reyadh Naoum
Abstract:
Society has grown to rely on Internet services, and the number of Internet users increases every day. As more and more users become connected to the network, the window of opportunity for malicious users to do their damage becomes very great and lucrative. The objective of this paper is to incorporate different techniques into classier system to detect and classify intrusion from normal network packet. Among several techniques, Steady State Genetic-based Machine Leaning Algorithm (SSGBML) will be used to detect intrusions. Where Steady State Genetic Algorithm (SSGA), Simple Genetic Algorithm (SGA), Modified Genetic Algorithm and Zeroth Level Classifier system are investigated in this research. SSGA is used as a discovery mechanism instead of SGA. SGA replaces all old rules with new produced rule preventing old good rules from participating in the next rule generation. Zeroth Level Classifier System is used to play the role of detector by matching incoming environment message with classifiers to determine whether the current message is normal or intrusion and receiving feedback from environment. Finally, in order to attain the best results, Modified SSGA will enhance our discovery engine by using Fuzzy Logic to optimize crossover and mutation probability. The experiments and evaluations of the proposed method were performed with the KDD 99 intrusion detection dataset.Keywords: MSSGBML, Network Intrusion Detection, SGA, SSGA.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1675731 Improving the Dissolution Rate of Folic Acid via the Antisolvent Vapour Precipitation
Authors: J. Y. Tan, L. C. Lum, M. G. Lee, S. Mansouri, K. Hapgood, X. D. Chen, M. W. Woo
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Folic acid (FA) is known to be an important supplement to prevent neural tube defect (NTD) in pregnant women. Similar to some commercial formulations, sodium bicarbonate solution is used as a solvent for FA. This work uses the antisolvent vapour precipitation (AVP), incorporating ethanol vapour as the convective drying medium in place of air to produce branch-like micro-structure FA particles. Interestingly, the dissolution rate of the resultant particle is 2-3 times better than the particle produce from conventional air drying due to the higher surface area of particles produced. The higher dissolution rate could possibly improve the delivery and absorption of FA in human body. This application could potentially be extended to other commercial products, particularly in less soluble drugs to improve its solubility.
Keywords: Absorption, antisolvent vapour precipitation, dissolution rate, folic acid.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2475730 Numerical Modeling of Steel-Composite Hybrid Tubes Subject to Static and Dynamic Loading
Authors: Y. S. Tai, M. Y. Huang, H. T. Hu
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The commercial finite element program LS-DYNA was employed to evaluate the response and energy absorbing capacity of cylindrical metal tubes that are externally wrapped with composite. The effects of composite wall thickness, loading conditions and fiber ply orientation were examined. The results demonstrate that a wrapped composite can be utilized effectively to enhance the crushing characteristics and energy absorbing capacity of the tubes. Increasing the thickness of the composite increases the mean force and the specific energy absorption under both static and dynamic crushing. The ply pattern affects the energy absorption capacity and the failure mode of the metal tube and the composite material property is also significant in determining energy absorption efficiency.
Keywords: fiber-reinforced metal tubes, energy absorption, axial crushing, impact loading.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2526729 Effect of Various Nozzle Profiles on Performance of a Two Phase Flow Jet Pump
Authors: Vishnu Prasad Sharma, S. Kumaraswamy, A. Mani
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This paper reports on the results of experimental investigations on the performance of a jet pump operated under selected primary flows to optimize the related parameters. For this purpose a two-phase flow jet pump was used employing various profiles of nozzles as the primary device which was designed, fabricated and used along with the combination of mixing tube and diffuser. The profiles employed were circular, conical, and elliptical. The diameter of the nozzle used was 4 mm. The area ratio of the jet pump was 0.16. The test facility created for this purpose was an open loop continuous circulation system. Performance of the jet pump was obtained as iso-efficiency curves on characteristic curves drawn for various water flow rates. To perform the suction capability, evacuation test was conducted at best efficiency point for all the profiles.
Keywords: Evacuation test, jet pump, nozzle profile, nozzle spacing, performance test, two phase flow
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3321728 Simulation of the Temperature and Heat Gain by Solar Parabolic Trough Collector in Algeria
Authors: M. Ouagued, A. Khellaf
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The objectif of the present work is to determinate the potential of the solar parabolic trough collector (PTC) for use in the design of a solar thermal power plant in Algeria. The study is based on a mathematical modeling of the PTC. Heat balance has been established respectively on the heat transfer fluid (HTF), the absorber tube and the glass envelop using the principle of energy conservation at each surface of the HCE cross-sectionn. The modified Euler method is used to solve the obtained differential equations. At first the results for typical days of two seasons the thermal behavior of the HTF, the absorber and the envelope are obtained. Then to determine the thermal performances of the heat transfer fluid, different oils are considered and their temperature and heat gain evolutions compared.Keywords: Direct solar irradiance, solar radiation in Algeria, solar parabolic trough collector, heat balance, thermal oil performance
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3657