Search results for: bioinformatics framework
1523 Multi-Agent Systems Applied in the Modeling and Simulation of Biological Problems: A Case Study in Protein Folding
Authors: Pedro Pablo González Pérez, Hiram I. Beltrán, Arturo Rojo-Domínguez, Máximo EduardoSánchez Gutiérrez
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Multi-agent system approach has proven to be an effective and appropriate abstraction level to construct whole models of a diversity of biological problems, integrating aspects which can be found both in "micro" and "macro" approaches when modeling this type of phenomena. Taking into account these considerations, this paper presents the important computational characteristics to be gathered into a novel bioinformatics framework built upon a multiagent architecture. The version of the tool presented herein allows studying and exploring complex problems belonging principally to structural biology, such as protein folding. The bioinformatics framework is used as a virtual laboratory to explore a minimalist model of protein folding as a test case. In order to show the laboratory concept of the platform as well as its flexibility and adaptability, we studied the folding of two particular sequences, one of 45-mer and another of 64-mer, both described by an HP model (only hydrophobic and polar residues) and coarse grained 2D-square lattice. According to the discussion section of this piece of work, these two sequences were chosen as breaking points towards the platform, in order to determine the tools to be created or improved in such a way to overcome the needs of a particular computation and analysis of a given tough sequence. The backwards philosophy herein is that the continuous studying of sequences provides itself important points to be added into the platform, to any time improve its efficiency, as is demonstrated herein.
Keywords: multi-agent systems, blackboard-based agent architecture, bioinformatics framework, virtual laboratory, protein folding.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 22061522 An Efficient and Generic Hybrid Framework for High Dimensional Data Clustering
Authors: Dharmveer Singh Rajput , P. K. Singh, Mahua Bhattacharya
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Clustering in high dimensional space is a difficult problem which is recurrent in many fields of science and engineering, e.g., bioinformatics, image processing, pattern reorganization and data mining. In high dimensional space some of the dimensions are likely to be irrelevant, thus hiding the possible clustering. In very high dimensions it is common for all the objects in a dataset to be nearly equidistant from each other, completely masking the clusters. Hence, performance of the clustering algorithm decreases. In this paper, we propose an algorithmic framework which combines the (reduct) concept of rough set theory with the k-means algorithm to remove the irrelevant dimensions in a high dimensional space and obtain appropriate clusters. Our experiment on test data shows that this framework increases efficiency of the clustering process and accuracy of the results.Keywords: High dimensional clustering, sub-space, k-means, rough set, discernibility matrix.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19481521 A Multi-Agent Framework for Data Mining
Authors: Kamal Ali Albashiri, Khaled Ahmed Kadouh
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A generic and extendible Multi-Agent Data Mining (MADM) framework, MADMF (the Multi-Agent Data Mining Framework) is described. The central feature of the framework is that it avoids the use of agreed meta-language formats by supporting a framework of wrappers. The advantage offered is that the framework is easily extendible, so that further data agents and mining agents can simply be added to the framework. A demonstration MADMF framework is currently available. The paper includes details of the MADMF architecture and the wrapper principle incorporated into it. A full description and evaluation of the framework-s operation is provided by considering two MADM scenarios.Keywords: Multi-Agent Data Mining (MADM), Frequent Itemsets, Meta ARM, Association Rule Mining, Classifier generator.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20741520 Meta-Learning for Hierarchical Classification and Applications in Bioinformatics
Authors: Fabio Fabris, Alex A. Freitas
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Hierarchical classification is a special type of classification task where the class labels are organised into a hierarchy, with more generic class labels being ancestors of more specific ones. Meta-learning for classification-algorithm recommendation consists of recommending to the user a classification algorithm, from a pool of candidate algorithms, for a dataset, based on the past performance of the candidate algorithms in other datasets. Meta-learning is normally used in conventional, non-hierarchical classification. By contrast, this paper proposes a meta-learning approach for more challenging task of hierarchical classification, and evaluates it in a large number of bioinformatics datasets. Hierarchical classification is especially relevant for bioinformatics problems, as protein and gene functions tend to be organised into a hierarchy of class labels. This work proposes meta-learning approach for recommending the best hierarchical classification algorithm to a hierarchical classification dataset. This work’s contributions are: 1) proposing an algorithm for splitting hierarchical datasets into new datasets to increase the number of meta-instances, 2) proposing meta-features for hierarchical classification, and 3) interpreting decision-tree meta-models for hierarchical classification algorithm recommendation.Keywords: Algorithm recommendation, meta-learning, bioinformatics, hierarchical classification.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 13701519 Polymorphic Marker Designed from Bioinformatics Sequences Related to Cell Wall Strength for Discrimination of Mangosteen (Garcinia mangostana L.) Clones Resistant to Gamboge Disorder
Authors: E. Mansyah, Sobir, E. Santosa, A. Sisharmini, Sulassih
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Gamboge disorder (GD) or fruit damage by the yellow sap is a major problem in mangosteen. Mangosteen plants varied in the level of GD, from very low or non GD to low, moderate and high GD. However it was difficult to differentiate between GD and non GD plants because evaluation of the disorder is strongly influenced by environment. In this study we investigated the usefulness of primer designed from bioinformatics related to cell wall strength, termed as MCWS, to predict GD. Plant materials used were 28 mangosteen plants selected based on percentage of GD categorized as high, moderate, low and very low or non GD. The result showed that the specific DNA fragments were absent in the high GD accessions. The MCWS marker suggests as a novel polymorphic marker for GD in mangosteen as well as a marker for detect variability in mangosteen as apomictic plant.
Keywords: Bioinformatics, cell wall strength, gamboge disorder, mangosteen, polymorphic marker.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 24241518 EEG Waves Classifier using Wavelet Transform and Fourier Transform
Authors: Maan M. Shaker
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The electroencephalograph (EEG) signal is one of the most widely signal used in the bioinformatics field due to its rich information about human tasks. In this work EEG waves classification is achieved using the Discrete Wavelet Transform DWT with Fast Fourier Transform (FFT) by adopting the normalized EEG data. The DWT is used as a classifier of the EEG wave's frequencies, while FFT is implemented to visualize the EEG waves in multi-resolution of DWT. Several real EEG data sets (real EEG data for both normal and abnormal persons) have been tested and the results improve the validity of the proposed technique.Keywords: Bioinformatics, DWT, EEG waves, FFT.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 55571517 Development of Fuzzy Logic Control Ontology for E-Learning
Authors: Muhammad Sollehhuddin A. Jalil, Mohd Ibrahim Shapiai, Rubiyah Yusof
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Nowadays, ontology is common in many areas like artificial intelligence, bioinformatics, e-commerce, education and many more. Ontology is one of the focus areas in the field of Information Retrieval. The purpose of an ontology is to describe a conceptual representation of concepts and their relationships within a particular domain. In other words, ontology provides a common vocabulary for anyone who needs to share information in the domain. There are several ontology domains in various fields including engineering and non-engineering knowledge. However, there are only a few available ontology for engineering knowledge. Fuzzy logic as engineering knowledge is still not available as ontology domain. In general, fuzzy logic requires step-by-step guidelines and instructions of lab experiments. In this study, we presented domain ontology for Fuzzy Logic Control (FLC) knowledge. We give Table of Content (ToC) with middle strategy based on the Uschold and King method to develop FLC ontology. The proposed framework is developed using Protégé as the ontology tool. The Protégé’s ontology reasoner, known as the Pellet reasoner is then used to validate the presented framework. The presented framework offers better performance based on consistency and classification parameter index. In general, this ontology can provide a platform to anyone who needs to understand FLC knowledge.
Keywords: Engineering knowledge, fuzzy logic control ontology, ontology development, table of contents.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 11741516 An Enterprise Intelligent System Development and Solution Framework
Authors: Rajendra M. Sonar
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The recent trend has been using hybrid approach rather than using a single intelligent technique to solve the problems. In this paper, we describe and discuss a framework to develop enterprise solutions that are backed by intelligent techniques. The framework not only uses intelligent techniques themselves but it is a complete environment that includes various interfaces and components to develop the intelligent solutions. The framework is completely Web-based and uses XML extensively. It can work like shared plat-form to be accessed by multiple developers, users and decision makers.Keywords: Intelligent System Development Framework, WebbasedIntelligent Systems, Retail Banking.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20151515 Testing Object-Oriented Framework Applications Using FIST2 Tool: A Case Study
Authors: Jehad Al Dallal
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An application framework provides a reusable design and implementation for a family of software systems. Frameworks are introduced to reduce the cost of a product line (i.e., a family of products that shares the common features). Software testing is a timeconsuming and costly ongoing activity during the application software development process. Generating reusable test cases for the framework applications during the framework development stage, and providing and using the test cases to test part of the framework application whenever the framework is used reduces the application development time and cost considerably. This paper introduces the Framework Interface State Transition Tester (FIST2), a tool for automated unit testing of Java framework applications. During the framework development stage, given the formal descriptions of the framework hooks, the specifications of the methods of the framework-s extensible classes, and the illegal behavior description of the Framework Interface Classes (FICs), FIST2 generates unitlevel test cases for the classes. At the framework application development stage, given the customized method specifications of the implemented FICs, FIST2 automates the use, execution, and evaluation of the already generated test cases to test the implemented FICs. The paper illustrates the use of the FIST2 tool for testing several applications that use the SalesPoint framework.Keywords: Automated testing, class testing, FICs, FIST2, object-oriented framework, object-oriented testing.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16181514 Metamodel for Artefacts in Service Engineering Analysis and Design
Authors: Purnomo Yustianto, Robin Doss
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As a process of developing a service system, the term ‘service engineering’ evolves in scope and definition. To achieve an integrated understanding of the process, a general framework and an ontology are required. This paper extends a previously built service engineering framework by exploring metamodels for the framework artefacts based on a foundational ontology and a metamodel landscape. The first part of this paper presents a correlation map between the proposed framework with the ontology as a form of evaluation for the conceptual coverage of the framework. The mapping also serves to characterize the artefacts to be produced for each activity in the framework. The second part describes potential metamodels to be used, from the metamodel landscape, as alternative formats of the framework artefacts. The results suggest that the framework sufficiently covers the ontological concepts, both from general service context and software service context. The metamodel exploration enriches the suggested artefact format from the original eighteen formats to thirty metamodel alternatives.
Keywords: Artefact, framework, service, metamodel.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 6451513 Development of Researcher Knowledge in Mathematics Education: Towards a Confluence Framework
Authors: I. Kontorovich, R. Zazkis
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We present a framework of researcher knowledge development in conducting a study in mathematics education. The key components of the framework are: knowledge germane to conducting a particular study, processes of knowledge accumulation, and catalyzing filters that influence a researcher decision making. The components of the framework originated from a confluence between constructs and theories in Mathematics Education, Higher Education and Sociology. Drawing on a self-reflective interview with a leading researcher in mathematics education, Professor Michèle Artigue, we illustrate how the framework can be utilized in data analysis. Criteria for framework evaluation are discussed.
Keywords: Community of practice, knowledge development, mathematics education research, researcher knowledge.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 18501512 Adequacy of Object-Oriented Framework System-Based Testing Techniques
Authors: Jehad Al Dallal
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An application framework provides a reusable design and implementation for a family of software systems. If the framework contains defects, the defects will be passed on to the applications developed from the framework. Framework defects are hard to discover at the time the framework is instantiated. Therefore, it is important to remove all defects before instantiating the framework. In this paper, two measures for the adequacy of an object-oriented system-based testing technique are introduced. The measures assess the usefulness and uniqueness of the testing technique. The two measures are applied to experimentally compare the adequacy of two testing techniques introduced to test objectoriented frameworks at the system level. The two considered testing techniques are the New Framework Test Approach and Testing Frameworks Through Hooks (TFTH). The techniques are also compared analytically in terms of their coverage power of objectoriented aspects. The comparison study results show that the TFTH technique is better than the New Framework Test Approach in terms of usefulness degree, uniqueness degree, and coverage power.Keywords: Object-oriented framework, object-oriented framework testing, test case generation, testing adequacy.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 14291511 Grid Computing in Physics and Life Sciences
Authors: Heinz Stockinger
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Certain sciences such as physics, chemistry or biology, have a strong computational aspect and use computing infrastructures to advance their scientific goals. Often, high performance and/or high throughput computing infrastructures such as clusters and computational Grids are applied to satisfy computational needs. In addition, these sciences are sometimes characterised by scientific collaborations requiring resource sharing which is typically provided by Grid approaches. In this article, I discuss Grid computing approaches in High Energy Physics as well as in bioinformatics and highlight some of my experience in both scientific domains.Keywords: Grid computing, Web services, physics, bioinformatics
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 15441510 Framework for the Modeling of the Supply Chain Collaborative Planning Process
Authors: D. Pérez, M. M. E. Alemany
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In this work, a framework to model the Supply Chain (SC) Collaborative Planning (CP) process is proposed. The main contributions of this framework concern 1) the presentation of the decision view, the most important one due to the characteristics of the process, jointly within the physical, organisation and information views, and 2) the simultaneous consideration of the spatial and temporal integration among the different supply chain decision centres. This framework provides the basis for a realistic and integrated perspective of the supply chain collaborative planning process and also the analytical modeling of each of its decisional activities.Keywords: Collaborative Planning, Decision View, Distributed Decision-Making, Framework.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 13231509 Design of Open Framework Based Smart ESS Profile for PV-ESS and UPS-ESS
Authors: Young-Su Ryu, Won-Gi Jeon, Byoung-Chul Song, Jae-Hong Park, Ki-Won Kwon
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In this paper, an open framework based smart energy storage system (ESS) profile for photovoltaic (PV)-ESS and uninterruptible power supply (UPS)-ESS is proposed and designed. An open framework based smart ESS is designed and developed for unifying the different interfaces among manufacturers. The smart ESS operates under the profile which provides the specifications of peripheral devices such as different interfaces and to the open framework. The profile requires well systemicity and expandability for addible peripheral devices. Especially, the smart ESS should provide the expansion with existing systems such as UPS and the linkage with new renewable energy technology such as PV. This paper proposes and designs an open framework based smart ESS profile for PV-ESS and UPS-ESS. The designed profile provides the existing smart ESS and also the expandability of additional peripheral devices on smart ESS such as PV and UPS.Keywords: ESS, open framework, profile, PV, UPS.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 11281508 WAF: an Interface Web Agent Framework
Authors: Xizhi Li, Qinming He
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A trend in agent community or enterprises is that they are shifting from closed to open architectures composed of a large number of autonomous agents. One of its implications could be that interface agent framework is getting more important in multi-agent system (MAS); so that systems constructed for different application domains could share a common understanding in human computer interface (HCI) methods, as well as human-agent and agent-agent interfaces. However, interface agent framework usually receives less attention than other aspects of MAS. In this paper, we will propose an interface web agent framework which is based on our former project called WAF and a Distributed HCI template. A group of new functionalities and implications will be discussed, such as web agent presentation, off-line agent reference, reconfigurable activation map of agents, etc. Their enabling techniques and current standards (e.g. existing ontological framework) are also suggested and shown by examples from our own implementation in WAF.Keywords: HCI, Interface agent, MAS.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16571507 A Novel Security Framework for the Web System
Authors: J. P. Dubois, P. G. Jreije
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In this paper, a framework is presented trying to make the most secure web system out of the available generic and web security technology which can be used as a guideline for organizations building their web sites. The framework is designed to provide necessary security services, to address the known security threats, and to provide some cover to other security problems especially unknown threats. The requirements for the design are discussed which guided us to the design of secure web system. The designed security framework is then simulated and various quality of service (QoS) metrics are calculated to measure the performance of this system.Keywords: Web Security, Internet Voting, Firewall, QoS, Latency, Utilization, Throughput.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 13441506 Intellectual Property Protection of CRISPR Related Technologies
Authors: Zheng Miao, Dennis Fernandez
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CRISPR research has the potential to completely transform life science, agriculture, live-stock and the health care industry. The Intellectual Property derived from its research has raised significant attention in the academic as well as the biopharmaceutical industry culminating an urgent need for strategic IP protection. We review the rudimentary concepts and key competitors of CRISPR technologies as well as the paramount strategies for intellectual property protection. Further, we elaborate on prosecution issues related to CRISPR patents as well as possible solutions to various patent laws, interferences and litigation. Finally, we address how the bioinformatics of the CRISPR technology begs an inquiry into issues of privacy and a host of ethical concerns.Keywords: Bioinformatics, CRISPR, biotechnology, intellectual property.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 23001505 A Collaborative Framework for Visual Modeling on Web 2.0
Authors: Song Meng, Dianfu Ma, Yongwang Zhao, Jianxin Li
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Cooperative visual modeling is more and more necessary in our complicated world. A collaborative environment which supports interactive operation and communication is required to increase work efficiency. We present a collaborative visual modeling framework which collaborative platform could be built on. On this platform, cooperation and communication is available for designers from different regions. This framework, which is different from other collaborative frameworks, contains a uniform message format, a message handling mechanism and other functions such as message pretreatment and Role-Communication-Token Access Control (RCTAC). We also show our implementation of this framework called Orchestra Designer, which support BPLE workflow modeling cooperatively online.Keywords: colllaborative framework; visual modeling; message handling mechanism
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 15621504 A Generalized Framework for Working with Multiagent Systems
Authors: Debal Saha, NirmalBaranHui
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The present paper discusses the basic concepts and the underlying principles of Multi-Agent Systems (MAS) along with an interdisciplinary exploitation of these principles. It has been found that they have been utilized for lots of research and studies on various systems spanning across diverse engineering and scientific realms showing the need of development of a proper generalized framework. Such framework has been developed for the Multi-Agent Systems and it has been generalized keeping in mind the diverse areas where they find application. All the related aspects have been categorized and a general definition has been given where ever possible.
Keywords: Generalized framework, multiagent systems.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 17831503 Towards Design of Context-Aware Sensor Grid Framework for Agriculture
Authors: Aqeel-ur-Rehman, Zubair A. Shaikh
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This paper is to present context-aware sensor grid framework for agriculture and its design challenges. Use of sensor networks in the domain of agriculture is not new. However, due to the unavailability of any common framework, solutions that are developed in this domain are location, environment and problem dependent. Keeping the need of common framework for agriculture, Context-Aware Sensor Grid Framework is proposed. It will be helpful in developing solutions for majority of the problems related to irrigation, pesticides spray, use of fertilizers, regular monitoring of plot and yield etc. due to the capability of adjusting according to location and environment. The proposed framework is composed of three layer architecture including context-aware application layer, grid middleware layer and sensor network layer.Keywords: Agriculture, Context-Awareness, Grid Computing, and Sensor Grid.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 25751502 Biological Data Integration using SOA
Authors: Noura Meshaan Al-Otaibi, Amin Yousef Noaman
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Nowadays scientific data is inevitably digital and stored in a wide variety of formats in heterogeneous systems. Scientists need to access an integrated view of remote or local heterogeneous data sources with advanced data accessing, analyzing, and visualization tools. This research suggests the use of Service Oriented Architecture (SOA) to integrate biological data from different data sources. This work shows SOA will solve the problems that facing integration process and if the biologist scientists can access the biological data in easier way. There are several methods to implement SOA but web service is the most popular method. The Microsoft .Net Framework used to implement proposed architecture.Keywords: Bioinformatics, Biological data, Data Integration, SOA and Web Services.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 24731501 Presenting an Integrated Framework for the Introduction and Evaluation of Social Media in Enterprises
Authors: Gerhard Peter
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In this paper, we present an integrated framework that governs the introduction of social media into enterprises and its evaluation. It is argued that the framework should address the following issues: (1) the contribution of social media for increasing efficiency and improving the quality of working life; (2) the level on which this contribution happens (i.e., individual, team, or organisation); (3) a description of the processes for implementing and evaluating social media; and the role of (4) organisational culture and (5) management. We also report the results of a case study where the framework has been employed to introduce a social networking platform at a German enterprise. This paper only considers the internal use of social media.Keywords: Case study, enterprise 2.0, framework, introducing and evaluating social media, social media.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 9151500 The Study of Digital Transformation Skills and Competencies Framework at Umm Alqura University
Authors: Anod H. Alhazmi, Hanaa A. Yamani
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The lack of digital transformation professionals could prevent Saudi Arabia’s universities from providing digital services. The task of understanding what digital skills are needed within an organization, measuring the existing skills, and developing or attracting talents is a complex task. This paper provides a comprehensive analysis of the digital transformation skills needed in the organizations who seek digital transformation and identifies the skills and competencies framework DigSC built on Skills Framework for the Informational Age (SFIA) framework that is adopted by the Ministry of Communications and Information Technology (MCIT) in Saudi Arabia. The framework adopted identifies the main digital transformation skills clusters, categories and levels of responsibilities for each job description to fill the gap between this requirement and the digital skills supplied by the Umm Alqura University (UQU).Keywords: Competencies, digital transformation, framework, skills, Umm Alqura University.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 5471499 Evaluation Framework for Agent-Oriented Methodologies
Authors: Zohreh O. Akbari, Ahmad Faraahi
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Many agent-oriented software engineering methodologies have been proposed for software developing; however their application is still limited due to their lack of maturity. Evaluating the strengths and weaknesses of these methodologies plays an important role in improving them and in developing new stronger methodologies. This paper presents an evaluation framework for agent-oriented methodologies, which addresses six major areas: concepts, notation, process, pragmatics, support for software engineering and marketability. The framework is then used to evaluate the Gaia methodology to identify its strengths and weaknesses, and to prove the ability of the framework for promoting the agent-oriented methodologies by detecting their weaknesses in detail.Keywords: Agent-Oriented Software Engineering, Evaluation Framework, Methodology.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20791498 Business Domain Modelling Using an Integrated Framework
Authors: Mohammed Salahat, Steve Wade
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This paper presents an application of a “Systematic Soft Domain Driven Design Framework” as a soft systems approach to domain-driven design of information systems development. The framework use SSM as a guiding methodology within which we have embedded a sequence of design tasks based on the UML leading to the implementation of a software system using the Naked Objects framework. This framework have been used in action research projects that have involved the investigation and modelling of business processes using object-oriented domain models and the implementation of software systems based on those domain models. Within this framework, Soft Systems Methodology (SSM) is used as a guiding methodology to explore the problem situation and to develop the domain model using UML for the given business domain. The framework is proposed and evaluated in our previous works, and a real case study “Information Retrieval System for academic research” is used, in this paper, to show further practice and evaluation of the framework in different business domain. We argue that there are advantages from combining and using techniques from different methodologies in this way for business domain modelling. The framework is overviewed and justified as multimethodology using Mingers multimethodology ideas.Keywords: SSM, UML, domain-driven design, soft domaindriven design, naked objects, soft language, information retrieval, multimethodology.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 17771497 Bioinformatics Profiling of Missense Mutations
Authors: I. Nassiri, B. Goliaei, M. Tavassoli
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The ability to distinguish missense nucleotide substitutions that contribute to harmful effect from those that do not is a difficult problem usually accomplished through functional in vivo analyses. In this study, instead current biochemical methods, the effects of missense mutations upon protein structure and function were assayed by means of computational methods and information from the databases. For this order, the effects of new missense mutations in exon 5 of PTEN gene upon protein structure and function were examined. The gene coding for PTEN was identified and localized on chromosome region 10q23.3 as the tumor suppressor gene. The utilization of these methods were shown that c.319G>A and c.341T>G missense mutations that were recognized in patients with breast cancer and Cowden disease, could be pathogenic. This method could be use for analysis of missense mutation in others genes.Keywords: Bioinformatics, missense mutations, PTEN tumorsuppressor gene.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 23901496 Design an Electronic Market Framework Using JADE Environment
Authors: Mohammad Ali Tabarzad, Caro Lucas
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The daily growing use of agents in software environments, because of many reasons such as independence and intelligence is not a secret anymore. One of such environments in which there is a prominent job for the agents would be emarketplaces in which a user is able to give those agents the responsibility of buying and selling, instead of searching the emarketplace himself. Making up a framework which has sufficient attention to the required roles and their relations, is the first step of achieving such e-markets. In this paper, we suggest a framework in order to establish such e-markets and we will continue investigating the roles such as seller or buyer and the relations in JADE environment in details.
Keywords: Framework, software agents, e-commerce, e-market.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 14411495 Generating Class-Based Test Cases for Interface Classes of Object-Oriented Gray-Box Frameworks
Authors: Jehad Al Dallal, Paul Sorenson
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An application framework provides a reusable design and implementation for a family of software systems. Application developers extend the framework to build their particular applications using hooks. Hooks are the places identified to show how to use and customize the framework. Hooks define Framework Interface Classes (FICs) and their possible specifications, which helps in building reusable test cases for the implementations of these classes. In applications developed using gray-box frameworks, FICs inherit framework classes or use them without inheritance. In this paper, a test-case generation technique is extended to build test cases for FICs built for gray-box frameworks. A tool is developed to automate the introduced technique.Keywords: Class testing, object-oriented framework, reusable test case.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 15171494 Into Insights of Contextual Governance Framework for Religious Non-Profit Organizations
Authors: Saunah Zainon, Ruhaya Atan, Nadzira Yahaya, Marshita Hashim
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Governance in business firms is a topic that has long been studied in the literature. Traditionally, governance in business firms has focused on the roles of boards of directors in representing and protecting the interests of shareholders. Governance has also been studied in the context of non-profit organizations because good governance is essential to increase the likelihood that they will comply with the regulatory requirements that best serve their multiple stakeholders. This paper provides insights on the need of governance framework for religious non-profit organizations (RNPOs) based on five underlying principles. This paper is important to help regulators to understand RNPOs’ governance framework. The regulators may use the framework suggested for the development of the RNPOs’ code of governance in the future.
Keywords: Framework, governance, religious, RNPOs.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1642