Search results for: Yong Poovorawan
168 In silico Analysis of Human microRNAs Targeting Influenza a Viruses (subtype H1N1, H5N1 and H3N2)
Authors: Kritsada Khongnomnan, Wittaya Poomipak, Yong Poovorawan, Sunchai Payungporn
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In this study, three subtypes of influenza A viruses (pH1N1, H5N1 and H3N2) which naturally infected human were analyzed by bioinformatic approaches to find candidate human cellular miRNAs targeting viral genomes. There were 76 miRNAs targeting influenza A viruses. Among these candidates, 70 miRNAs were subtypes specifically targeting each subtype of influenza A virus including 21 miRNAs targeted subtype H1N1, 27 miRNAs targeted subtype H5N1 and 22 miRNAs targeted subtype H3N2. The remaining 6 miRNAs target on multiple subtypes of influenza A viruses. Uniquely, hsa-miR-3145 is the only one candidate miRNA targeting PB1 gene of all three subtypes. Obviously, most of the candidate miRNAs are targeting on polymerase complex genes (PB2, PB1 and PA) of influenza A viruses. This study predicted potential human miRNAs targeting on different subtypes of influenza A viruses which might be useful for inhibition of viral replication and for better understanding of the interaction between virus and host cell.
Keywords: Human miRNAs, Influenza A viruses, H1N1, H5N1, H3N2
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1493167 Analysis of SCR-Based ESD Protection Circuit on Holding Voltage Characteristics
Authors: Yong Seo Koo, Jong Ho Nam, Yong Nam Choi, Dae Yeol Yoo, Jung Woo Han
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This paper presents a silicon controller rectifier (SCR) based ESD protection circuit for IC. The proposed ESD protection circuit has low trigger voltage and high holding voltage compared with conventional SCR ESD protection circuit. Electrical characteristics of the proposed ESD protection circuit are simulated and analyzed using TCAD simulator. The proposed ESD protection circuit verified effective low voltage ESD characteristics with low trigger voltage and high holding voltage.
Keywords: ESD (Electro-Static Discharge), SCR (Silicon Controlled Rectifier), holding Voltage.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3734166 Characterization of a Novel Galactose-Binding Lectin Homologue from Tenebrio molitor
Authors: JiEun Jeong, Dong Hyun Kim, Bharat Bhusan Patnaik, Se Won Kang, HeeJu Hwang, Yong Hun Jo, Dae-Hyun Seog, YeonSooHan, Yong Seok Lee
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An expressed sequence tag (EST) analysis provideus portions of expressed genes. We have constructed cDNA library and determined randomly sequences from cDNA library clones of T. molitor injected with acholeplasma lysate. We identified the homologous to a galectin gene. As the result of cloning and characterization of novel, we found that the protein has an open reading frame (ORF) of 495 bp, with 164 amino acid residues and molecular weight of 18.5 kDa. To characterize the role of novel Tm-galectin in immune system, we quantified the mRNA level of galectin at different times after treatment with immune elicitors. The galectin mRNA was up-regulated about 7-folds within 18 hrs. This suggests that Tm-galectin is a novel member of animal lectins, and has a role in the process of pathogen recognition. Our study would be helpful for the study on immune defense system and signaling cascade.
Keywords: EST, Innate immunity, Tenebrio molitor, Galectin.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2016165 Evaluation of Graph-based Analysis for Forest Fire Detections
Authors: Young Gi Byun, Yong Huh, Kiyun Yu, Yong Il Kim
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Spatial outliers in remotely sensed imageries represent observed quantities showing unusual values compared to their neighbor pixel values. There have been various methods to detect the spatial outliers based on spatial autocorrelations in statistics and data mining. These methods may be applied in detecting forest fire pixels in the MODIS imageries from NASA-s AQUA satellite. This is because the forest fire detection can be referred to as finding spatial outliers using spatial variation of brightness temperature. This point is what distinguishes our approach from the traditional fire detection methods. In this paper, we propose a graph-based forest fire detection algorithm which is based on spatial outlier detection methods, and test the proposed algorithm to evaluate its applicability. For this the ordinary scatter plot and Moran-s scatter plot were used. In order to evaluate the proposed algorithm, the results were compared with the MODIS fire product provided by the NASA MODIS Science Team, which showed the possibility of the proposed algorithm in detecting the fire pixels.Keywords: Spatial Outlier Detection, MODIS, Forest Fire
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2226164 Synthesis and Applications of Heteronanostructured ZnO Nanowires Array
Authors: Minsu Seol, Youngjo Tak, Guenjai Kwak, Kijung Yong
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ZnO heteronanostructured nanowires arrays have been fabricated by low temperature solution method. Various heterostructures were synthesized including CdS/ZnO, CdSe/CdS/ZnO nanowires and Co3O4/ZnO, ZnO/SiC nanowires. These multifunctional heterostructure nanowires showed important applications in photocatalysts, sensors, wettability control and solar energy conversion.Keywords: ZnO nanowires, Heterostructure nanowires, solarenergy conversion, photocatalsis.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2117163 Equal Sharing Solutions for Bicooperative Games
Authors: Fan-Yong Meng, Yan Wang
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In this paper, we discuss the egalitarianism solution (ES) and center-of-gravity of the imputation-set value (CIV) for bicooperative games, which can be seen as the extensions of the solutions for traditional games given by Dutta and Ray [1] and Driessen and Funaki [2]. Furthermore, axiomatic systems for the given values are proposed. Finally, a numerical example is offered to illustrate the player ES and CTV.
Keywords: Bicooperative games, egalitarianism solution, center of- gravity of the imputation-set value.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1339162 Disparity Estimation for Objects of Interest
Authors: Yen San Yong, Hock Woon Hon
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An algorithm for estimating the disparity of objects of interest is proposed. This algorithm uses image shifting and overlapping area to estimate the disparity value; thereby depth of the objects of interest can be obtained. The algorithm is able to perform at different levels of accuracy. However, as the accuracy increases the processing speed decreases. The algorithm is tested with static stereo images and sequence of stereo images. The experimental results are presented in this paper.Keywords: stereo vision, binocular parallax
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1230161 Implementing High Performance VPN Router using Cavium-s CN2560 Security Processor
Authors: Sang Su Lee, Sang Woo Lee, Yong Sung Jeon, Ki Young Kim
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IPsec protocol[1] is a set of security extensions developed by the IETF and it provides privacy and authentication services at the IP layer by using modern cryptography. In this paper, we describe both of H/W and S/W architectures of our router system, SRS-10. The system is designed to support high performance routing and IPsec VPN. Especially, we used Cavium-s CN2560 processor to implement IPsec processing in inline-mode.Keywords: IP, router, VPN, IPsec.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2034160 Production of As Isotopes in the Interaction of natGe with 14-30 MeV Protons
Authors: Yong H. Chung, Eun J. Han, Seil Lee, Sun Y. Park, Eun H. Yoon, Eun J. Cho, Jang H. Lee, Young J. Chu, Jang H. Ha, Jongseo Chai, Yu S. Kim, Min Y. Lee, Hyeyoung Lee
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Cross sections of As radionuclides in the interaction of natGe with 14-30 MeV protons have been deduced by off-line y-ray spectroscopy to find optimal reaction channels leading to radiotracers for positron emission tomography. The experimental results were compared with the previous results and those estimated by the compound nucleus reaction model.
Keywords: Compound nucleus reaction model, off-line g-ray spectroscopy, radionuclide.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1540159 Existence of Solution of Nonlinear Second Order Neutral Stochastic Differential Inclusions with Infinite Delay
Authors: Yong Li
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The paper is concerned with the existence of solution of nonlinear second order neutral stochastic differential inclusions with infinite delay in a Hilbert Space. Sufficient conditions for the existence are obtained by using a fixed point theorem for condensing maps.
Keywords: Mild solution, Convex multivalued map, Neutral stochastic differential inclusions.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1604158 Modified Fuzzy PID Control for Networked Control Systems with Random Delays
Authors: Yong-can Cao, Wei-dong Zhang
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To deal with random delays in Networked Control System (NCS), Modified Fuzzy PID Controller is introduced in this paper to implement real-time control adaptively. Via adjusting the control signal dynamically, the system performance is improved. In this paper, the design process and the ultimate simulation results are represented. Finally, examples and corresponding comparisons prove the significance of this method.
Keywords: Fuzzy Control, Networked Control System, PID, Random Delays
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1556157 The Banzhaf-Owen Value for Fuzzy Games with a Coalition Structure
Authors: Fan-Yong Meng
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In this paper, a generalized form of the Banzhaf-Owen value for cooperative fuzzy games with a coalition structure is proposed. Its axiomatic system is given by extending crisp case. In order to better understand the Banzhaf-Owen value for fuzzy games with a coalition structure, we briefly introduce the Banzhaf-Owen values for two special kinds of fuzzy games with a coalition structure, and give their explicit forms.
Keywords: Cooperative fuzzy game, Banzhaf-Owen value, multi linear extension, Choquet integral.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1555156 Cross-Search Technique and its Visualization of Peer-to-Peer Distributed Clinical Documents
Authors: Yong Jun Choi, Juman Byun, Simon Berkovich
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One of the ubiquitous routines in medical practice is searching through voluminous piles of clinical documents. In this paper we introduce a distributed system to search and exchange clinical documents. Clinical documents are distributed peer-to-peer. Relevant information is found in multiple iterations of cross-searches between the clinical text and its domain encyclopedia.
Keywords: Clinical documents, cross-search, document exchange, information retrieval, peer-to-peer.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1302155 Algorithm for Bleeding Determination Based On Object Recognition and Local Color Features in Capsule Endoscopy
Authors: Yong-Gyu Lee, Jin Hee Park, Youngdae Seo, Gilwon Yoon
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Automatic determination of blood in less bright or noisy capsule endoscopic images is difficult due to low S/N ratio. Especially it may not be accurate to analyze these images due to the influence of external disturbance. Therefore, we proposed detection methods that are not dependent only on color bands. In locating bleeding regions, the identification of object outlines in the frame and features of their local colors were taken into consideration. The results showed that the capability of detecting bleeding was much improved.Keywords: Endoscopy, object recognition, bleeding, image processing, RGB.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1939154 Structure-vibration Analysis of a Power Transformer(154kV/60MVA/Single Phase)
Authors: Young-Dal Kim, Jae-Myung Shim, Woo-Yong Park, Sung-joong Kim, Dong Seok Hyun, Dae-Dong Lee
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The most common cause of power transformer failures is mechanical defect brought about by excessive vibration, which is formed by the combination of multiples of a frequency of 120 Hz. In this paper, the types of mechanical exciting forces applied to the power transformer were classified, and the mechanical damage mechanism of the power transformer was identified using the vibration transfer route to the machine or structure. The general effects of 120 Hz-vibration on the enclosure, bushing, Buchholz relay, pressure release valve and tap changer of the transformer were also examined.Keywords: Structure-Vibration, Transformer.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3454153 Bleeding Detection Algorithm for Capsule Endoscopy
Authors: Yong-Gyu Lee, Gilwon Yoon
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Automatic detection of bleeding is of practical importance since capsule endoscopy produces an extremely large number of images. Algorithm development of bleeding detection in the digestive tract is difficult due to different contrasts among the images, food dregs, secretion and others. In this study, were assigned weighting factors derived from the independent features of the contrast and brightness between bleeding and normality. Spectral analysis based on weighting factors was fast and accurate. Results were a sensitivity of 87% and a specificity of 90% when the accuracy was determined for each pixel out of 42 endoscope images.Keywords: bleeding, capsule endoscopy, image analysis, weighted spectrum
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2119152 A Study on a Research and Development Cost-Estimation Model in Korea
Authors: Babakina Alexandra, Yong Soo Kim
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In this study, we analyzed the factors that affect research funds using linear regression analysis to increase the effectiveness of investments in national research projects. We collected 7,916 items of data on research projects that were in the process of being finished or were completed between 2010 and 2011. Data pre-processing and visualization were performed to derive statistically significant results. We identified factors that affected funding using analysis of fit distributions and estimated increasing or decreasing tendencies based on these factors.
Keywords: R&D funding, Cost estimation, Linear regression, Preliminary feasibility study.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2246151 The Projection Methods for Computing the Pseudospectra of Large Scale Matrices
Authors: Zhengsheng Wang, Xiangyong Ji, Yong Du
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The projection methods, usually viewed as the methods for computing eigenvalues, can also be used to estimate pseudospectra. This paper proposes a kind of projection methods for computing the pseudospectra of large scale matrices, including orthogonalization projection method and oblique projection method respectively. This possibility may be of practical importance in applications involving large scale highly nonnormal matrices. Numerical algorithms are given and some numerical experiments illustrate the efficiency of the new algorithms.Keywords: Pseudospectra, eigenvalue, projection method, Arnoldi, IOM(q)
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1324150 Sulfamonomethoxine-Induced Urinary Calculiin Pigs
Authors: Wei-Dong Sun, Ke-Chun Zhang, Jin-Yong Wang, Xiao-Long Wang
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The authors report a case of swine urolithiasis caused by improper administration of sulfamonomethoxine and which was diagnosed by examination of urinary sediments and analyzing the composition of the uroliths. The chemical composition of urinary calculi obtained from affected pigs with urolithiasis was further confimed as sulfamonomethoxine by fourier transform infrared (FTIR). It is suggested that appearance of typical fanlike or wheat bunchy crystals in urinary sediments under observation of lightmicroscope and determination by FTIR for the crystals are helpful in diagnosing sulfa calculi causced swine urolithiasis.Keywords: Calculi, pig, sulfamonomethoxine.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1884149 A Virtual Simulation Environment for a Design and Verification of a GPGPU
Authors: Kwang Y. Lee, Tae R. Park, Jae C. Kwak, Yong S. Koo
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When a small H/W IP is designed, we can develop an appropriate verification environment by observing the simulated signal waves, or using the serial test vectors for the fixed output. In the case of design and verification of a massive parallel processor with multiple IPs, it-s difficult to make a verification system with existing common verification environment, and to verify each partial IP. A TestDrive verification environment can build easy and reliable verification system that can produce highly intuitive results by applying Modelsim and SystemVerilog-s DPI. It shows many advantages, for example a high-level design of a GPGPU processor design can be migrate to FPGA board immediately.Keywords: Virtual Simulation, Verification, IP Design, GPGPU
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1661148 Improved Wi-Fi Backscatter System for Multi-to-Multi Communication
Authors: Chang-Bin Ha, Yong-Jun Kim, Dong-Hyun Ha, Hyoung-Kyu Song
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The conventional Wi-Fi backscatter system can only process one-to-one communication between the Wi-Fi reader and the Wi-Fi tag. For improvement of throughput of the conventional system, this paper proposes the multi-to-multi communication system. In the proposed system, the interference by the multi-to-multi communication is effectively cancelled by the orthogonal multiple access based on the identification code of the tag. Although the overhead is generated by the procedure for the multi-to-multi communication, because the procedure is processed by the Wi-Fi protocol, the overhead is insignificant for the entire communication procedure. From the numerical results, it is confirmed that the proposed system has nearly proportional increased throughput in according to the number of the tag that simultaneously participates in communication.Keywords: Backscatter, Multi-to-multi communication, Orthogonality, Wi-Fi.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2075147 The Study on the Wireless Power Transfer System for Mobile Robots
Authors: Hyung-Nam Kim, Won-Yong Chae, Dong-Sul Shin, Ho-Sung Kim, Hee-Je Kim
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A wireless power transfer system can attribute to the fields in robot, aviation and space in which lightening the weight of device and improving the movement play an important role. A wireless power transfer system was investigated to overcome the inconvenience of using power cable. Especially a wireless power transfer technology is important element for mobile robots. We proposed the wireless power transfer system of the half-bridge resonant converter with the frequency tracking and optimized power transfer control unit. And the possibility of the application and development system was verified through the experiment with LED loads.Keywords: Wireless Power Transmission (WPT), resonancefrequency, protection circuit. LED.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2697146 The Core and Shapley Function for Games on Augmenting Systems with a Coalition Structure
Authors: Fan-Yong Meng
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In this paper, we first introduce the model of games on augmenting systems with a coalition structure, which can be seen as an extension of games on augmenting systems. The core of games on augmenting systems with a coalition structure is defined, and an equivalent form is discussed. Meantime, the Shapley function for this type of games is given, and two axiomatic systems of the given Shapley function are researched. When the given games are quasi convex, the relationship between the core and the Shapley function is discussed, which does coincide as in classical case. Finally, a numerical example is given.
Keywords: Cooperative game, augmenting system, Shapley function, core.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1195145 SCR-Based Advanced ESD Protection Device for Low Voltage Application
Authors: Bo Bae Song, Byung Seok Lee, Hyun Young Kim, Chung Kwang Lee, Yong Seo Koo
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This paper proposed a silicon controller rectifier (SCR) based ESD protection device to protect low voltage ESD for integrated circuit. The proposed ESD protection device has low trigger voltage and high holding voltage compared with conventional SCR-based ESD protection devices. The proposed ESD protection circuit is verified and compared by TCAD simulation. This paper verified effective low voltage ESD characteristics with low trigger voltage of 5.79V and high holding voltage of 3.5V through optimization depending on design variables (D1, D2, D3 and D4).
Keywords: ESD, SCR, Holding voltage, Latch-up.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2890144 Efficient Variable Modulation Scheme Based on Codebook in the MIMO-OFDM System
Authors: Yong-Jun Kim, Jae-Hyun Ro, Chang-Bin Ha, Hyoung-Kyu Song
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Because current wireless communication requires high reliability in a limited bandwidth environment, this paper proposes the variable modulation scheme based on the codebook. The variable modulation scheme adjusts transmission power using the codebook in accordance with channel state. Also, if the codebook is composed of many bits, the reliability is more improved by the proposed scheme. The simulation results show that the performance of proposed scheme has better reliability than the the performance of conventional scheme.Keywords: MIMO-OFDM, variable modulation, codebook, channel state.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1822143 A New Method for Estimation of the Source Coherency Structure of Wideband Sources
Authors: Yong-jun Zhao, Heng-li Zhang, Zong-yun Hu
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Based on the sources- smoothed rank profile (SRP) and modified minimum description length (MMDL) principle, a method for estimation of the source coherency structure (SCS) and the number of wideband sources is proposed in this paper. Instead of focusing, we first use a spatial smoothing technique to pre-process the array covariance matrix of each frequency for de-correlating the sources and then use smoothed rank profile to determine the SCS and the number of wideband sources. We demonstrate the availability of the method by numerical simulations.
Keywords: Wideband sources, source coherency structure (SCS), smoothed rank profile (SRP).
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1317142 Approximation Incremental Training Algorithm Based on a Changeable Training Set
Authors: Yi-Fan Zhu, Wei Zhang, Xuan Zhou, Qun Li, Yong-Lin Lei
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The quick training algorithms and accurate solution procedure for incremental learning aim at improving the efficiency of training of SVR, whereas there are some disadvantages for them, i.e. the nonconvergence of the formers for changeable training set and the inefficiency of the latter for a massive dataset. In order to handle the problems, a new training algorithm for a changeable training set, named Approximation Incremental Training Algorithm (AITA), was proposed. This paper explored the reason of nonconvergence theoretically and discussed the realization of AITA, and finally demonstrated the benefits of AITA both on precision and efficiency.Keywords: support vector regression, incremental learning, changeable training set, quick training algorithm, accurate solutionprocedure
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1484141 Using Multi-Thread Technology Realize Most Short-Path Parallel Algorithm
Authors: Chang-le Lu, Yong Chen
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The shortest path question is in a graph theory model question, and it is applied in many fields. The most short-path question may divide into two kinds: Single sources most short-path, all apexes to most short-path. This article mainly introduces the problem of all apexes to most short-path, and gives a new parallel algorithm of all apexes to most short-path according to the Dijkstra algorithm. At last this paper realizes the parallel algorithms in the technology of C # multithreading.Keywords: Dijkstra algorithm, parallel algorithms, multi-thread technology, most short-path, ratio.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2111140 Electrical Characteristics of SCR - based ESD Device for I/O and Power Rail Clamp in 0.35um Process
Authors: Yong Seo Koo, Dong Su Kim, Byung Seok Lee, Won Suk Park, Bo Bea Song
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This paper presents a SCR-based ESD protection devices for I/O clamp and power rail clamp, respectably. These devices have a low trigger voltage and high holding voltage characteristics than conventional SCR device. These devices are fabricated by using 0.35um BCD (Bipolar-CMOS-DMOS) processes. These devices were validated using a TLP system. From the experimental results, the device for I/O ESD clamp has a trigger voltage of 5.8V. Also, the device for power rail ESD clamp has a holding voltage of 7.7V.
Keywords: ESD (Electro-Static Discharge), ESD protection device, SCR (Silicon Controlled Rectifier), Latch-up
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2774139 Ultrasonic System for Diagnosis of Functional Gastrointestinal Disorders: Development, Verification and Clinical Trials
Authors: Eun-Geun Kim, Won-Pil Park, Dae-Gon Woo, Chang-Yong Ko, Yong-Heum Lee, Dohyung Lim, Tae-Min Shin, Han-Sung Kim, Gyoun-Jung Lee
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Functional gastrointestinal disorders affect millions of people spread all age regardless of race and sex. There are, however, rare diagnostic methods for the functional gastrointestinal disorders because functional disorders show no evidence of organic and physical causes. Our research group identified recently that the gastrointestinal tract well in the patients with the functional gastrointestinal disorders becomes more rigid than healthy people when palpating the abdominal regions overlaying the gastrointestinal tract. Aim of this study is, therefore, to develop a diagnostic system for the functional gastrointestinal disorders based on ultrasound technique, which can quantify the characteristic above related to the rigidity of the gastrointestinal tract well. Ultrasound system was designed. The system consisted of transmitter, ultrasonic transducer, receiver, TGC, and CPLD, and verified via a phantom test. For the phantom test, ten soft-tissue specimens were harvested from porcine. Five of them were then treated chemically to mimic a rigid condition of gastrointestinal tract well, which was induced by functional gastrointestinal disorders. Additionally, the specimens were tested mechanically to identify if the mimic was reasonable. The customized ultrasound system was finally verified through application to human subjects with/without functional gastrointestinal disorders (Normal and Patient Groups). It was identified from the mechanical test that the chemically treated specimens were more rigid than normal specimen. This finding was favorably compared with the result obtained from the phantom test. The phantom test also showed that ultrasound system well described the specimen geometric characteristics and detected an alteration in the specimens. The maximum amplitude of the ultrasonic reflective signal in the rigid specimens (0.2±0.1Vp-p) at the interface between the fat and muscle layers was explicitly higher than that in the normal specimens (0.1±0.0Vp-p). Clinical tests using our customized ultrasound system for human subject showed that the maximum amplitudes of the ultrasonic reflective signals near to the gastrointestinal tract well for the patient group (2.6±0.3Vp-p) were generally higher than those in normal group (0.1±0.2Vp-p). Here, maximum reflective signals was appeared at 20mm depth approximately from abdominal skin for all human subjects, corresponding to the location of the boundary layer close to gastrointestinal tract well. These results suggest that newly designed diagnostic system based on ultrasound technique may diagnose enough the functional gastrointestinal disorders.Keywords: Functional Gastrointestinal Disorders, DiagnosticSystem, Phantom Test, Ultrasound System.
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