Search results for: integrability conditions
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 9786

Search results for: integrability conditions

4896 Dynamic Software Product Lines for Customer Centric Context Aware Business Process Management

Authors: Bochra Khiari, Lamia Labed

Abstract:

In the new digital marketplace, organizations are striving for a proactive position by leveraging the great potential of disruptive technologies to seize the full opportunity of the digital revolution in order to reshape their customer value propositions. New technologies such as big data analytics, which provide prediction of future events based on real-time information, are being integrated into BPM which urges the need for additional core values like capabilities for dynamic adaptation, autonomic behavior, runtime reconfiguration and post-deployment activities to manage unforeseen scenarios at runtime in a situated and changeable context. Dynamic Software Product Lines (DSPL) is an emerging paradigm that supports these runtime variability mechanisms. However, few works exploiting DSPLs principles and techniques in the BPM domain have been proposed so far. In this paper, we propose a conceptual approach DynPL4CBPM, which integrates DSPLs concepts along with the entire related dynamic properties, to the whole BPM lifecycle in order to dynamically adapt business processes according to different context conditions in an individual environment.

Keywords: adaptive processes, context aware business process management, customer centric business process management, dynamic software product lines

Procedia PDF Downloads 157
4895 The Effect of Extremely Low Frequency Magnetic Field on Rats Brain

Authors: Omar Abdalla, Abdelfatah Ahmed, Ahmed Mustafa, Abdelazem Eldouma

Abstract:

The purpose of this study is evaluating the effect of extremely low frequency magnetic field on Waster rats brain. The number of rats used in this study were 25, which were divided into five groups, each group containing five rats as follows: Group 1: The control group which was not exposed to energized field; Group 2: Rats were exposed to a magnetic field with an intensity of 0.6 mT (2 hours/day); Group 3: Rats were exposed to a magnetic field of 1.2 mT (2 hours/day); Group4: Rats were exposed to a magnetic field of 1.8 mT (2 hours/day); Group 5: Rats were exposed to a magnetic field of 2.4 mT (2 hours/day) and all groups were exposed for seven days, by designing a maze and calculating the time average for arriving to the decoy at special conditions. We found the time average before exposure for the all groups was G2=330 s, G3=172 s, G4=500 s and G5=174 s, respectively. We exposed all groups to ELF-MF and measured the time and we found: G2=465 s, G3=388 s, G4=501 s, and G5=442 s. It was observed that the time average increased directly with field strength. Histological samples of frontal lop of brain for all groups were taken and we found lesion, atrophy, empty vacuoles and disorder choroid plexus at frontal lope of brain. And finally we observed the disorder of choroid plexus in histological results and Alzheimer's symptoms increase when the magnetic field increases.

Keywords: nonionizing radiation, biophysics, magnetic field, shrinkage

Procedia PDF Downloads 540
4894 Pharmaceutical Applications of Newton's Second Law and Disc Inertia

Authors: Nicholas Jensen

Abstract:

As the effort to create new drugs to treat rare conditions cost-effectively intensifies, there is a need to ensure maximum efficiency in the manufacturing process. This includes the creation of ultracompact treatment forms, which can best be achieved via applications of fundamental laws of physics. This paper reports an experiment exploring the relationship between the forms of Newton's 2ⁿᵈ Law appropriate to linear motion and to transversal architraves. The moment of inertia of three discs was determined by experiments and compared with previous data derived from a theoretical relationship. The method used was to attach the discs to a moment arm. Comparing the results with those obtained from previous experiments, it is found to be consistent with the first law of thermodynamics. It was further found that Newton's 2ⁿᵈ law violates the second law of thermodynamics. The purpose of this experiment was to explore the relationship between the forms of Newton's 2nd Law appropriate to linear motion and to apply torque to a twisting force, which is determined by position vector r and force vector F. Substituting equation alpha in place of beta; angular acceleration is a linear acceleration divided by radius r of the moment arm. The nevrological analogy of Newton's 2nd Law states that these findings can contribute to a fuller understanding of thermodynamics in relation to viscosity. Implications for the pharmaceutical industry will be seen to be fruitful from these findings.

Keywords: Newtonian physics, inertia, viscosity, pharmaceutical applications

Procedia PDF Downloads 112
4893 Advanced Electrocoagulation for Textile Wastewater Treatment

Authors: Alemi Asefa Wordofa

Abstract:

The textile industry is among the biggest industries in the world, producing a wide variety of products. Industry plays an important role in the world economy as well as in our daily lives. In Ethiopia, this has also been aided by the country’s impressive economic growth over the years. However, Textile industries consume large amounts of water and produce colored wastewater, which results in polluting the environment. In this study, the efficiency of the electrocoagulation treatment process using Iron electrodes to treat textile wastewater containing Reactive black everzol was studied. The effects of parameters such as voltage, time of reaction, and inter-electrode distance on Chemical oxygen demand (COD) and dye removal efficiency were investigated. In addition, electrical energy consumption at optimum conditions has been investigated. The results showed that COD and dye removals were 90.76% and 97.66%, respectively, at the optimum point of input voltage of 14v, inter-electrode distance of 7.24mm, and 47.86min electrolysis time. Energy consumption at the optimum point is also 2.9*10-3. It can be concluded that the electrocoagulation process by the iron electrode is a very efficient and clean process for COD and reactive black removal from wastewater.

Keywords: iron electrode, electrocoagulation, chemical oxygen demand, wastewater

Procedia PDF Downloads 61
4892 Analytical Modelling of Surface Roughness during Compacted Graphite Iron Milling Using Ceramic Inserts

Authors: Ş. Karabulut, A. Güllü, A. Güldaş, R. Gürbüz

Abstract:

This study investigates the effects of the lead angle and chip thickness variation on surface roughness during the machining of compacted graphite iron using ceramic cutting tools under dry cutting conditions. Analytical models were developed for predicting the surface roughness values of the specimens after the face milling process. Experimental data was collected and imported to the artificial neural network model. A multilayer perceptron model was used with the back propagation algorithm employing the input parameters of lead angle, cutting speed and feed rate in connection with chip thickness. Furthermore, analysis of variance was employed to determine the effects of the cutting parameters on surface roughness. Artificial neural network and regression analysis were used to predict surface roughness. The values thus predicted were compared with the collected experimental data, and the corresponding percentage error was computed. Analysis results revealed that the lead angle is the dominant factor affecting surface roughness. Experimental results indicated an improvement in the surface roughness value with decreasing lead angle value from 88° to 45°.

Keywords: CGI, milling, surface roughness, ANN, regression, modeling, analysis

Procedia PDF Downloads 443
4891 Public Transport Assignment at Adama City

Authors: Selamawit Mulubrhan Gidey

Abstract:

Adama city, having an area of 29.86 km2, is one of the main cities in Ethiopia experiencing rapid growth in business and construction activities which in turn with an increasing number of vehicles at an alarming rate. For this reason, currently, there is an attempt to develop public transport assignment modeling in the city. Still, there is a huge gap in developing public transport assignments along the road segments of the city with operational and safety performance due to high traffic volume. Thus, the introduction of public transport assignment modeling in Adama City can have a massive impact on the road safety and capacity problem in the city. City transport modeling is important in city transportation planning, particularly in overcoming existing transportation problems such as traffic congestion. In this study, the Adama City transportation model was developed using the PTV VISUM software, whose transportation modeling is based on the four-step model of transportation. Based on the traffic volume data fed and simulated, the result of the study shows that the developed model has better reliability in representing the traffic congestion conditions in Adama city, and the simulation clearly indicates the level of congestion of each route selected and thus, the city road administrative office can take managerial decisions on public transport assignment so as to overcome traffic congestion executed along the selected routes.

Keywords: trip modelling, PTV VISUM, public transport assignment, congestion

Procedia PDF Downloads 30
4890 A Comparative Study on Indian and Greek Cotton Fiber Properties Correlations

Authors: Md. Nakib Ul Hasan, Md. Ariful Islam, Md. Sumon Miah, Misbah Ul Hoque, Bulbul Ahmed

Abstract:

The variability of cotton fiber characteristics has always been influenced by origin, weather conditions, method of culturing, and harvesting. Spinners work tirelessly to ensure consistent yarn quality by using the different origins of fibers to maximizes the profit margin. Spinners often fail to select desired raw materials of various origins to achieve an appropriate mixing plan due to the lack of knowledge on the interrelationship among fiber properties. The purpose of this research is to investigate the correlations among dominating fiber properties such as micronaire, strength, breaking elongation, upper half mean length, length uniformity index, short fiber index, maturity, reflectance, and yellowness. For this purpose, fiber samples from 500 Indian cotton bales and 350 Greek cotton bales were collected and tested using the high volume instrument (HVI). The fiber properties dataset was then compiled and analyzed using python 3.7 to determine the correlations matrix. Results show that Indian cotton fiber have highest correlation between strength-mat = 0.84, followed by SFI-Unf =-0.83, and Neps-Unf = -0.72. Greek cotton fiber, in contrast, have highest correlation between SFI-Unf =-0.98, followed by SFI-Mat = 0.89, +b-Len = 0.84, and Str-Mat = 0.74. Overall, the Greek cotton fiber showed a higher correlational matrix than compared to that of Indian cotton fiber.

Keywords: cotton fiber, fiber properties correlation, Greek cotton, HVI, Indian cotton, spinning

Procedia PDF Downloads 157
4889 A Computational Fluid Dynamics Study of Turbulence Flow and Parameterization of an Aerofoil

Authors: Mohamed Z. M. Duwahir, Shian Gao

Abstract:

The main objective of this project was to introduce and test a new scheme for parameterization of subsonic aerofoil, using a function called Shape Function. Python programming was used to create a user interactive environment for geometry generation of aerofoil using NACA and Shape Function methodologies. Two aerofoils, NACA 0012 and NACA 1412, were generated using this function. Testing the accuracy of the Shape Function scheme was done by Linear Square Fitting using Python and CFD modelling the aerofoil in Fluent. NACA 0012 (symmetrical aerofoil) was better approximated using Shape Function than NACA 1412 (cambered aerofoil). The second part of the project involved comparing two turbulent models, k-ε and Spalart-Allmaras (SA), in Fluent by modelling the aerofoils NACA 0012 and NACA 1412 in conditions of Reynolds number of 3 × 106. It was shown that SA modelling is better for aerodynamic purpose. The experimental coefficient of lift (Cl) and coefficient of drag (Cd) were compared with empirical wind tunnel data for a range of angle of attack (AOA). As a further step, this project involved drawing and meshing 3D wings in Gambit. The 3D wing flow was solved and compared with 2D aerofoil section experimental results and wind tunnel data.

Keywords: CFD simulation, shape function, turbulent modelling, aerofoil

Procedia PDF Downloads 354
4888 Strength Investigation of Liquefied Petroleum Gas Cylinders: Dynamic Loads

Authors: Moudar Zgoul, Hashem Alkhaldi

Abstract:

A large number of transportable LPG cylinders are manufactured annually for domestic use. These LPG cylinders are manufactured from mild steel and filled maximally with 12.5 kg liquefied gas under internal pressure of 0.6 N/mm² at a temperature of 50°C. Many millions of such LPG cylinders are in daily use mainly, for purposes of space heating, water heating, and cooking. Thereby, they are imposed to severe conditions leading to their failure. Each year not less than 5000 of these LPG cylinders fail, some of those failures cause damage and loss in lives and properties. In this work, LPG cylinders were investigated; Stress calculations and deformations under dynamic (impact) loadings were carried out to simulate the effects of such loads on the cylinders while in service. Analysis of the LPG cylinders was carried out using the finite element method; shell and cylindrical elements were used at the top, bottom, and in middle (weld region), permitting elastic-plastic analysis for a thin-walled LPG cylinder. Variables such as maximum stresses and maximum deflections under the effect of impact loading were investigated in this work. Results showed that the maximum stresses reach 680 MPa when dropped from 3m-height. The maximum radial deformation occurs at the cylinder’s top in case of the top-position impact. This information should be useful for enhancing the strength of such cylinders and to for prolonging their service life.

Keywords: dynamic analysis, finite element method, impact load, LPG cylinders

Procedia PDF Downloads 318
4887 From the Himalayas to Australia: A Review of the Literature on Teaching and Learning with Nepalese Students in the Higher Education Sector

Authors: Sangeeta Rai

Abstract:

International education is Australia’s third largest export with significant revenue flowing to the economy in all state and territory jurisdictions. International students make significant economic, social and cultural contributions to all communities in which they are studying and often working. Among these international students are those from Nepal, who continue to seek Australian higher education in increasing numbers. This paper reports on findings from a literature review that highlights the gap in knowledge of the pedagogical issues that may need addressing in teaching Nepalese students in the higher education sector in Australia. Nepalese students bring to their studies a rich culture shaped by their country’s turbulent political and poor economic conditions. These factors may further contribute to their endeavors to seek education abroad to better themselves and their situation. This cohort of students faces various challenges undertaking their studies in Australia that may be due to factors including language, learning styles and engagement with peers. Hence, this paper highlights the importance of these students on Australian shores and forms the basis for further study on the issues and challenges that they face and those that need to be addressed by Australian educators.

Keywords: Nepalese students in Australia, challenges and coping mechanisms of Nepalese students, international students in Australia, socio-cultural background of Nepalese students

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4886 Illegal Migration and Refugee Crisis as a Threat to National Security, Economic and Social System: The Bulgarian Case

Authors: Jordan Deliversky

Abstract:

Unlike all conventional forms of migration, migration crisis and migratory processes provide pressure to governments and are being expressed as different phenomenon in relation to nature and forms. The objective of this paper is to present the migration and refugee crisis as revealing numerous challenges faced by authorities responsible for the social and economic stability in Bulgaria as well as those providing conditions for reinforcement of the high level of national security in Bulgaria. The analysis is focused on exploring the multiple origins of factors influencing migration processes in Europe, in the light of the measures provided by the Bulgarian state authorities. The main results show that the society itself is facing the challenge of integrating refugees and migrants, so to be able to comply with the principles and values associated with tolerance to social, religious and cultural differences, and not allowing migrants to become marginalized community. Migration pressure creates a number of risks and threats to the Bulgarian national security. Our country has the capacity and resources to meet these potential threats, as a main factor for minimizing the risks to national security is the improvement of coordination and coherence of actions between various actors serving to the security sector.

Keywords: legislation, migrants, refugees, security, terrorism

Procedia PDF Downloads 338
4885 Laboratory Model Tests on Encased Group Columns

Authors: Kausar Ali

Abstract:

There are several ground treatment techniques which may meet the twin objectives of increasing the bearing capacity with simultaneous reduction of settlements, but the use of stone columns is one of the most suited techniques for flexible structures such as embankments, oil storage tanks etc. that can tolerate some settlement and used worldwide. However, when the stone columns in very soft soils are loaded; stone columns undergo excessive settlement due to low lateral confinement provided by the soft soil, leading to the failure of the structure. The poor performance of stone columns under these conditions can be improved by encasing the columns with a suitable geosynthetic. In this study, the effect of reinforcement on bearing capacity of composite soil has been investigated by conducting laboratory model tests on floating and end bearing long stone columns with l/d ratio of 12. The columns were reinforced by providing geosynthetic encasement over varying column length (upper 25%, 50%, 75%, and 100% column length). In this study, a group of columns has been used instead of single column, because in the field, columns used for the purpose always remain in groups. The tests indicate that the encasement over the full column length gives higher failure stress as compared to the encasement over the partial column length for both floating and end bearing long columns. The performance of end-bearing columns was found much better than the floating columns.

Keywords: geosynthetic, ground improvement, soft clay, stone column

Procedia PDF Downloads 428
4884 Multipurpose Agricultural Robot Platform: Conceptual Design of Control System Software for Autonomous Driving and Agricultural Operations Using Programmable Logic Controller

Authors: P. Abhishesh, B. S. Ryuh, Y. S. Oh, H. J. Moon, R. Akanksha

Abstract:

This paper discusses about the conceptual design and development of the control system software using Programmable logic controller (PLC) for autonomous driving and agricultural operations of Multipurpose Agricultural Robot Platform (MARP). Based on given initial conditions by field analysis and desired agricultural operations, the structural design development of MARP is done using modelling and analysis tool. PLC, being robust and easy to use, has been used to design the autonomous control system of robot platform for desired parameters. The robot is capable of performing autonomous driving and three automatic agricultural operations, viz. hilling, mulching, and sowing of seeds in the respective order. The input received from various sensors on the field is later transmitted to the controller via ZigBee network to make the changes in the control program to get desired field output. The research is conducted to provide assistance to farmers by reducing labor hours for agricultural activities by implementing automation. This study will provide an alternative to the existing systems with machineries attached behind tractors and rigorous manual operations on agricultural field at effective cost.

Keywords: agricultural operations, autonomous driving, MARP, PLC

Procedia PDF Downloads 359
4883 Experimental Investigation of Hybrid Rocket Motor: Ignition, Throttling and Re-Ignition Phenomena

Authors: A. El-S. Makled, M. K. Al-Tamimi

Abstract:

Ignition phenomena are of great interest area over the past many years, and it has a direct impact on many propulsion and combustion applications. The direct goal of the paper is to realize and evaluate a functioning ignition method, shut-off, throttling and re-start operations for the hybrid rocket motor. A small-scale hybrid rocket motor (SSHRM) is designed, manufactured, demonstrated at various operating conditions and finally equipped for laboratory firing tests with high level of safety. Various solid fuel grains as Polymethyle-methacrylate (PMMA) and Polyethylene (PE) are selected, and it is decided to use the commercial gaseous oxygen (GO2) for its availability and low cost. Examine different types of ignition methods, pyrotechnic charge, fuse wire, heat wire and finally hot oxidizer method by using the heat exchanger, which are proposed as very safe ignition methods. Finally; recognize phenomena of throttling and re-start operations. Ignition by hot GO2 impingement is proved to be a very attractive ignition method for laboratory SSHRM, for its high safety, reliability and acceptable delay time. Finally; the throttling and re-start operations are demonstrated several times and can be carried out more easily with hot air ignition method.

Keywords: hybrid rocket motor, ignition system, re-start phenomena, throttling

Procedia PDF Downloads 297
4882 Gender Effects in EEG-Based Functional Brain Networks

Authors: Mahdi Jalili

Abstract:

Functional connectivity in the human brain can be represented as a network using electroencephalography (EEG) signals. Network representation of EEG time series can be an efficient vehicle to understand the underlying mechanisms of brain function. Brain functional networks – whose nodes are brain regions and edges correspond to functional links between them – are characterized by neurobiologically meaningful graph theory metrics. This study investigates the degree to which graph theory metrics are sex dependent. To this end, EEGs from 24 healthy female subjects and 21 healthy male subjects were recorded in eyes-closed resting state conditions. The connectivity matrices were extracted using correlation analysis and were further binarized to obtain binary functional networks. Global and local efficiency measures – as graph theory metrics– were computed for the extracted networks. We found that male brains have a significantly greater global efficiency (i.e., global communicability of the network) across all frequency bands for a wide range of cost values in both hemispheres. Furthermore, for a range of cost values, female brains showed significantly greater right-hemispheric local efficiency (i.e., local connectivity) than male brains.

Keywords: EEG, brain, functional networks, network science, graph theory

Procedia PDF Downloads 439
4881 Correlation of Building Density toward Land Surface Temperature 2018 in Medan City

Authors: Andi Syahputra, R. H. Jatmiko, D. R. Hizbaron

Abstract:

Land surface temperature (LST) in an area is influenced by conditions of vegetation density, building density, and the number of inhabitants who live in the area. Medan City is one of the largest cities in Indonesia, with a high rate of change from vegetation to developed land. This study aims to identify the relationship between the percentage of building density and land surface temperature in Medan City. Pixel image analysis method is carried out to obtain the value of building density in pixel images of Landsat 8 images with the help of WorldView-2 satellite imagery. The results showed the highest land surface temperature in 2018 of 35, 4°C was found in Medan Perjuangan District, and the lowest was 22.5°C in Medan Belawan District. Building density samples with a density level of 889.17 m were also found in Medan Perjuangan District, while the lowest building density sample was found in Medan Timur District. Linear regression analysis of the effect of building density with land surface temperature obtained a correlation (R) was 0.64, and a coefficient of determination (R²) was 0.411 and modeling of building density based on the LST has a correlation (R), and a coefficient of determination (R²) was 0.72 with The RMSE obtained 0.853.

Keywords: land surface temperature, Landsat, imagery, building density, vegetation, density

Procedia PDF Downloads 147
4880 Cold Spray Deposition of SS316L Powders on Al5052 Substrates and Their Potential Using for Biomedical Applications

Authors: B. Dikici, I. Ozdemir, M. Topuz

Abstract:

The corrosion behaviour of 316L stainless steel coatings obtained by cold spray method was investigated in this study. 316L powders were deposited onto Al5052 aluminum substrates. The coatings were produced using nitrogen (N2) process gas. In order to further improve the corrosion and mechanical properties of the coatings, heat treatment was applied at 250 and 750 °C. The corrosion performances of the coatings were compared using the potentiodynamic scanning (PDS) technique under in-vitro conditions (in Ringer’s solution at 37 °C). In addition, the hardness and porosity tests were carried out on the coatings. Microstructural characterization of the coatings was carried out by using scanning electron microscopy attached with energy dispersive spectrometer (SEM-EDS) and X-ray diffraction (XRD) technique. It was found that clean surfaces and a good adhesion were achieved for particle/substrate bonding. The heat treatment process provided both elimination of the anisotropy in the coating and resulting in healing-up of the incomplete interfaces between the deposited particles. It was found that the corrosion potential of the annealed coatings at 750 °C was higher than that of commercially 316 L stainless steel. Moreover, the microstructural investigations after the corrosion tests revealed that corrosion preferentially starts at inter-splat boundaries.

Keywords: biomaterials, cold spray, 316L, corrosion, heat treatment

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4879 The Contribution of Diet and Lifestyle Factors in the Prevalence of Irritable Bowel Syndrome

Authors: Alexander Dao, Oscar Wambuguh

Abstract:

Irritable Bowel Syndrome (IBS) is a heterogeneous functional bowel disease that is characterized by chronic visceral abdominal pain and abnormal bowel function and habits. Its multifactorial pathophysiology and mechanisms are still largely a mystery to the contemporary biomedical community, although there are many hypotheses to try to explain IBS’s presumed physiological, psychosocial, genetic, and environmental etiologies. IBS’s symptomatic presentation is varied and divided into four major subtypes: IBS-C, IBS-D, IBS-M, and IBS-U. Given its diverse presentation and unclear mechanisms, diagnosis is done through a combination of positive identification utilizing the “Rome IV Irritable Bowel Syndrome Criteria'' (Rome IV) diagnostic criteria while also excluding other potential conditions with similar symptoms. Treatment of IBS is focused on the management of symptoms using an assortment of pharmaceuticals, lifestyle changes, and dietary changes, with future potential in microbial treatment and psychotherapy as other therapy methods. Its chronic, heterogeneous nature and disruptive gastrointestinal (GI) symptoms are negatively impactful on patients’ daily lives, health systems, and society. However, with a better understanding of the gaps in knowledge and technological advances in IBS’s pathophysiology, management, and treatment options, there is optimism for the millions of people worldwide who are suffering from the debilitating effects of IBS.

Keywords: irritable bowel syndrome, lifestyle, diet, functional gastrointestinal disorder

Procedia PDF Downloads 82
4878 Dependence of the Structural, Electrical and Magnetic Properties of YBa2Cu3O7−δ Bulk Superconductor on the Sm Doping

Authors: Raheleh Hajilou

Abstract:

In this study, we report the synthesis and characterization of YBa2Cu3O7-δ (YBCO) high-temperature superconductor prepared by solid-state method and doped with Sm in different weight percentages, 0, 0.01, 0.02 and 0.05 wt. The result of X-ray diffraction (XRD) analysis conforms to the formation of an orthorhombic phase of superconductivity in our samples. This is an important finding and indicates that the samples may exhibit superconductivity properties at certain conditions. Our results unequivocally point to a different structural order or disorder in SM/Y samples as compared to Sm based samples. We suggest that different site preferences of oxygen vacancies, predominantly created in CuO2 planes (CuO chains) of Y and Sm-based samples, might be responsible for the observed difference in the behavior. This contention is supported by a host of other considerations and experimental observations. The study investigated the effects of Sm doping on the YBCO system on various properties such as structural, critical temperature (Tc), scanning electron microscope (SEM), irresistibility line(IL), critical current density, jc, and flux line pinning force. It Seems the sample x=0.05 undergoes an insulator transition, which suppresses its superconducting transition temperature (Tc). Additionally, magnetization was measured as a function of temperature (M-T) and magnetic loops (M-H) at constant temperatures of 10. 20, 30, 40, 50 and 60K up to 10KG.

Keywords: high-Tc superconductors, Scanning electron microscopy, X-ray scattering, Irreversibility line

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4877 Prediction of Incompatibility Between Excipients and API in Gliclazide Tablets Using Infrared Spectroscopy and Principle Component Analysis

Authors: Farzad Khajavi

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Recognition of the interaction between active pharmaceutical ingredients (API) and excipients is a pivotal factor in the development of all pharmaceutical dosage forms. By predicting the interaction between API and excipients, we will be able to prevent the advent of impurities or at least lessen their amount. In this study, we used principle component analysis (PCA) to predict the interaction between Gliclazide as a secondary amine with Lactose in pharmaceutical solid dosage forms. The infrared spectra of binary mixtures of Gliclazide with Lactose at different mole ratios were recorded, and the obtained matrix was analyzed with PCA. By plotting score columns of the analyzed matrix, the incompatibility between Gliclazide and Lactose was observed. This incompatibility was seen experimentally. We observed the appearance of the impurity originated from the Maillard reaction between Gliclazide and Lactose at the chromatogram of the manufactured tablets in room temperature and under accelerated stability conditions. This impurity increases at the stability months. By changing Lactose to Mannitol and using Calcium Dibasic Phosphate in the tablet formulation, the amount of the impurity decreased and was in the acceptance range defined by British pharmacopeia for Gliclazide Tablets. This method is a fast and simple way to predict the existence of incompatibility between excipients and active pharmaceutical ingredients.

Keywords: PCA, gliclazide, impurity, infrared spectroscopy, interaction

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4876 Decision Support System in Air Pollution Using Data Mining

Authors: E. Fathallahi Aghdam, V. Hosseini

Abstract:

Environmental pollution is not limited to a specific region or country; that is why sustainable development, as a necessary process for improvement, pays attention to issues such as destruction of natural resources, degradation of biological system, global pollution, and climate change in the world, especially in the developing countries. According to the World Health Organization, as a developing city, Tehran (capital of Iran) is one of the most polluted cities in the world in terms of air pollution. In this study, three pollutants including particulate matter less than 10 microns, nitrogen oxides, and sulfur dioxide were evaluated in Tehran using data mining techniques and through Crisp approach. The data from 21 air pollution measuring stations in different areas of Tehran were collected from 1999 to 2013. Commercial softwares Clementine was selected for this study. Tehran was divided into distinct clusters in terms of the mentioned pollutants using the software. As a data mining technique, clustering is usually used as a prologue for other analyses, therefore, the similarity of clusters was evaluated in this study through analyzing local conditions, traffic behavior, and industrial activities. In fact, the results of this research can support decision-making system, help managers improve the performance and decision making, and assist in urban studies.

Keywords: data mining, clustering, air pollution, crisp approach

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4875 Heterogeneous Catalytic Hydroesterification of Soybean Oil to Develop a Biodiesel Formation

Authors: O. Mowla, E. Kennedy, M. Stockenhuber

Abstract:

Finding alternative renewable resources of energy has attracted the attentions in consequence of limitation of the traditional fossil fuel resources, increasing of crude oil price and environmental concern over greenhouse gas emissions. Biodiesel (or Fatty Acid Methyl Esters (FAME)), an alternative energy source, is synthesised from renewable sources such as vegetable oils and animal fats and can be produced from waste oils. FAME can be produced via hydroesterification of oils. The process involves two stages. In the first stage of this process, fatty acids and glycerol are being obtained by hydrolysis of the feed stock oil. In the second stage, the recovered fatty acids are then esterified with an alcohol to methyl esters. The presence of a catalyst accelerates the rate of the hydroesterification reaction of oils. The overarching aim of this study is to find the effect of using zeolite as a catalyst in the heterogeneous hydroesterification of soybean oil. Both stages of the catalytic hydroesterification of soybean oil had been conducted at atmospheric and high-pressure conditions using reflux glass reactor and Parr reactor, respectively. The effect of operating parameters such as temperature and reaction time on the overall yield of biodiesel formation was also investigated.

Keywords: biodiesel, heterogeneous catalytic hydroesterification, soybean oil, zeolite

Procedia PDF Downloads 425
4874 Air Quality Analysis Using Machine Learning Models Under Python Environment

Authors: Salahaeddine Sbai

Abstract:

Air quality analysis using machine learning models is a method employed to assess and predict air pollution levels. This approach leverages the capabilities of machine learning algorithms to analyze vast amounts of air quality data and extract valuable insights. By training these models on historical air quality data, they can learn patterns and relationships between various factors such as weather conditions, pollutant emissions, and geographical features. The trained models can then be used to predict air quality levels in real-time or forecast future pollution levels. This application of machine learning in air quality analysis enables policymakers, environmental agencies, and the general public to make informed decisions regarding health, environmental impact, and mitigation strategies. By understanding the factors influencing air quality, interventions can be implemented to reduce pollution levels, mitigate health risks, and enhance overall air quality management. Climate change is having significant impacts on Morocco, affecting various aspects of the country's environment, economy, and society. In this study, we use some machine learning models under python environment to predict and analysis air quality change over North of Morocco to evaluate the climate change impact on agriculture.

Keywords: air quality, machine learning models, pollution, pollutant emissions

Procedia PDF Downloads 89
4873 Laying the Proto-Ontological Conditions for Floating Architecture as a Climate Adaptation Solution for Rising Sea Levels: Conceptual Framework and Definition of a Performance Based Design

Authors: L. Calcagni, A. Battisti, M. Hensel, D. S. Hensel

Abstract:

Since the beginning of the 21st century, we have seen a dynamic growth of water-based (WB) architecture, mainly due to the increasing threat of floods caused by sea level rise and heavy rains, all correlated with climate change. At the same time, the shortage of land available for urban development also led architects, engineers, and policymakers to reclaim the seabed or to build floating structures. Furthermore, the drive to produce energy from renewable resources has expanded the sector of offshore research, mining, and energy industry which seeks new types of WB structures. In light of these considerations, the time is ripe to consider floating architecture as a full-fledged building typology. Currently, there is no universally recognized academic definition of a floating building. Research on floating architecture lacks a proper, commonly shared vocabulary and typology distinction. Moreover, there is no global international legal framework for urban development on water, and there is no structured performance based building design (PBBD) approach for floating architecture in most countries, let alone national regulatory systems. Thus, first of all, the research intends to overcome the semantic and typological issues through the conceptualization of floating architecture, laying the proto-ontological conditions for floating development, and secondly to identify the parameters to be considered in the definition of a specific PBBD framework, setting the scene for national planning strategies. The theoretical overview and re-semanticization process involve the attribution of a new meaning to the term floating architecture. This terminological work of semantic redetermination is carried out through a systematic literature review and involves quantitative and historical research as well as logical argumentation methods. As it is expected that floating urban development is most likely to take place as an extension of coastal areas, the needs and design criteria are definitely more similar to those of the urban environment than to those of the offshore industry. Therefore, the identification and categorization of parameters –looking towards the potential formation of a PBBD framework for floating development– takes the urban and architectural guidelines and regulations as the starting point, taking the missing aspects, such as hydrodynamics (i.e. stability and buoyancy) from the offshore and shipping regulatory frameworks. This study is carried out through an evidence-based assessment of regulatory systems that are effective in different countries around the world, addressing on-land and on-water architecture as well as offshore and shipping industries. It involves evidence-based research and logical argumentation methods. Overall, inhabiting water is proposed not only as a viable response to the problem of rising sea levels, thus as a resilient frontier for urban development, but also as a response to energy insecurity, clean water, and food shortages, environmental concerns, and urbanization, in line with Blue Economy principles and the Agenda 2030. This review shows how floating architecture is to all intents and purposes, an urban adaptation measure and a solution towards self-sufficiency and energy-saving objectives. Moreover, the adopted methodology is, to all extents, open to further improvements and integrations, thus not rigid and already completely determined. Along with new designs and functions that will come into play in the practice field, eventually, life on water will seem no more unusual than life on land, especially by virtue of the multiple advantages it provides not only to users but also to the environment.

Keywords: adaptation measures, building typology, floating architecture, performance based building design, rising sea levels

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4872 Detection of Cyberattacks on the Metaverse Based on First-Order Logic

Authors: Sulaiman Al Amro

Abstract:

There are currently considerable challenges concerning data security and privacy, particularly in relation to modern technologies. This includes the virtual world known as the Metaverse, which consists of a virtual space that integrates various technologies and is therefore susceptible to cyber threats such as malware, phishing, and identity theft. This has led recent studies to propose the development of Metaverse forensic frameworks and the integration of advanced technologies, including machine learning for intrusion detection and security. In this context, the application of first-order logic offers a formal and systematic approach to defining the conditions of cyberattacks, thereby contributing to the development of effective detection mechanisms. In addition, formalizing the rules and patterns of cyber threats has the potential to enhance the overall security posture of the Metaverse and, thus, the integrity and safety of this virtual environment. The current paper focuses on the primary actions employed by avatars for potential attacks, including Interval Temporal Logic (ITL) and behavior-based detection to detect an avatar’s abnormal activities within the Metaverse. The research established that the proposed framework attained an accuracy of 92.307%, resulting in the experimental results demonstrating the efficacy of ITL, including its superior performance in addressing the threats posed by avatars within the Metaverse domain.

Keywords: security, privacy, metaverse, cyberattacks, detection, first-order logic

Procedia PDF Downloads 36
4871 Analytical Solution of Blassius Equation Using the Kourosh Method

Authors: Mohammad Reza Shahnazari, Reza Kazemi, Ali Saberi

Abstract:

Most of the engineering problems are in nonlinear forms. Nonlinear boundary layer problems defined in infinite intervals contain specific complexities, especially in boundary layer condition conformance. As an example of these nonlinear complex problems, the well-known Blasius equation can be mentioned, which itself is one of the classic boundary layer problems. No analytical solution has been proposed yet for the Blasius equation due to its complexity. In this paper, an analytical method, namely the Kourosh method, based on the singularity perturbation method and the Liao homotopy analysis is utilized to solve the Blasius problem. In this method, an inner solution is developed in the [0,1] interval to expedite the solution convergence. The magnitude of the f ˝(0), as an essential quantity for determining the physical parameters, is directly calculated from the solution of the boundary condition problem. The advantages of this solution are that it does not need any numerical solution, it has a closed form and that its validation is shown in the entire [0,∞] interval. Furthermore, all of the desirable parameters could be extracted through a series of simple analytical operations from the final solution. This solution also satisfies the continuity conditions, which is one of the main contributions of this paper in comparison with most of the other proposed analytical solutions available in the literature. Comparison with numerical solutions reveals that the proposed method is highly accurate and convenient for application.

Keywords: Blasius equation, boundary layer, Kourosh method, analytical solution

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4870 Assessing the Impact of Underground Cavities on Buildings with Stepped Foundations on Sloping Lands

Authors: Masoud Mahdavi

Abstract:

The use of sloping lands is increasing due to the reduction of suitable lands for the construction of buildings. In the design and construction of buildings on sloping lands, the foundation has special loading conditions that require the designer and executor to use the slopped foundation. The creation of underground cavities, including urban and subway tunnels, sewers, urban facilities, etc., inside the ground, causes the behavior of the foundation to be unknown. In the present study, using Abacus software, a 45-degree stepped foundation on the ground is designed. The foundations are placed on the ground in a cohesive (no-hole) manner with circular cavities that show the effect of increasing the cross-sectional area of ​​the underground cavities on the foundation's performance. The Kobe earthquake struck the foundation and ground for two seconds. The underground cavities have a circular cross-sectional area with a radius of 5 m, which is located at a depth of 22.54 m above the ground. The results showed that as the number of underground cavities increased, von Mises stress (in the vertical direction) increased. With the increase in the number of underground cavities, the plastic strain on the ground has increased. Also, with the increase in the number of underground cavities, the change in location and speed in the foundation has increased.

Keywords: stepped foundation, sloping ground, Kobe earthquake, Abaqus software, underground excavations

Procedia PDF Downloads 151
4869 Integrated Wastewater Reuse Project of the Faculty of Sciences AinChock, Morocco

Authors: Nihad Chakri, Btissam El Amrani, Faouzi Berrada, Fouad Amraoui

Abstract:

In Morocco, water scarcity requires the exploitation of non-conventional resources. Rural areas are under-equipped with sanitation infrastructure, unlike urban areas. Decentralized and low-cost solutions could improve the quality of life of the population and the environment. In this context, the Faculty of Sciences Ain Chock "FSAC" has undertaken an integrated project to treat part of its wastewater using a decentralized compact system. The project will propose alternative solutions that are inexpensive and adapted to the context of peri-urban and rural areas in order to treat the wastewater generated and use it for irrigation, watering, and cleaning. For this purpose, several tests were carried out in the laboratory in order to develop a liquid waste treatment system optimized for local conditions. Based on the results obtained at the laboratory scale of the different proposed scenarios, we designed and implemented a prototype of a mini wastewater treatment plant for the Faculty. In this article, we will outline the steps of dimensioning, construction, and monitoring of the mini-station in our Faculty.

Keywords: wastewater, purification, optimization, vertical filter, MBBR process, sizing, decentralized pilot, reuse, irrigation, sustainable development

Procedia PDF Downloads 108
4868 Quality of Life of Patients on Oral Anticoagulant Therapy in Outpatient Cardiac Department Dr. Hasan Sadikin Central General Hospital Bandung

Authors: Mochammad Indra Permana, Andhiani Sharfina Arnellya, Dika Pramita Destiani, Budhi Prihartanto

Abstract:

Cardiovascular disease is the cause of the highest mortality rates in the world. The number of cardiovascular disease patients is increasing every year. Data obtained from World Health Organization (WHO) that 17,5 million people died from this disease. The condition of cardiovascular diseases such as atrial fibrillation, myocardial infarction, venous thromboembolism, and several other conditions need anticoagulant therapy. Results of the anticoagulant therapy are measured not only by the effectiveness of International Normalized Ratio (INR) value but also by the quality of life of the patients. The purpose of this study was to determine the quality of life of patients on oral anticoagulant therapy in outpatient cardiac department Dr. Hasan Sadikin central general hospital, Bandung, Indonesia. This is a cross-sectional study with collecting data from the quality of life questionnaire and medical record of the patients. The results of this study showed that 28 patients (46,7%) had a good quality of life, 30 patients (50%) had a moderate quality of life, and 2 patients (3,3%) had a poor quality of life with no significant differences in quality of life based on age, gender, diagnosis, and duration of drug use.

Keywords: anticoagulant, cardiovascular diseases, INR, quality of life

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4867 Effect of Graphene Oxide Nanoparticles on a Heavy Oilfield: Interfacial Tension, Wettability and Oil Displacement Studies

Authors: Jimena Lizeth Gomez Delgado, Jhon Jairo Rodriguez, Nicolas Santos, Enrique Mejia Ospino

Abstract:

Nanotechnology has played an important role in the hydrocarbon industry, recently , due to the unique properties of graphene oxide nanoparticles, they have been incorporated in different studies enhanced oil recovery. Nonetheless, very few studies have used graphene oxide nanoparticles in coreflooding experiments. Herein, the use of Graphene oxide (GO) nanoparticle was explored, exploited and evaluated. The performance of Graphene oxide nanoparticles on the interfacial properties in the presence of different electrolyte concentrations representative of field brine and pH conditions was investigated. Moreover, wettability behavior of the nanofluid at the oil/sand interface was studied used contact angle and Amott Harvey evaluation. Experimental result shows that the adsorption of GO on the sandstone surface changes the wettability of the sandstone from being strongly crude oil-wet to intermediate crude oil-wettability. At 900 ppm formation brine with 8 pH solution and 0.09 wt% nanoparticles concentration, Graphene oxide nanofluid exhibited better performance under the different electrolyte concentration studied. Finally, heavy oil displacement test in sandstone cores showed that oil recovery of Graphene oxide nanofluid had 7% incremental oil recovery over conventional waterflooding.

Keywords: nanoparticle, graphene oxide, nanotechnology, wettability, enhanced oil recovery, coreflooding

Procedia PDF Downloads 101