Search results for: DNA binding studies
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 2306

Search results for: DNA binding studies

2156 Technological Forecasting on Phytotherapics Development in Brazil

Authors: Simões, Evelyne Rolim Braun, Marques, Lana Grasiela Alves, Soares, Bruno Marques Pinheiro, Daniel Pascoalino, Santos, Maria Rita Morais Chaves, Pessoa, Claudia

Abstract:

The prospective analysis is presented as an important tool to identify the most relevant opportunities and needs in research and development from planned interventions in innovation systems. This study chose Phyllanthus niruri, known as "stone break" to describe the knowledge about the specie, by using biotechnological forecasting through the software Vantage Point. It can be seen a considerable increase in studies on Phyllanthus niruri in recent years and that there are patents about this plant since twenty-five years ago. India was the country that most carried out research on the specie, showing interest, mainly in studies of hepatoprotection, antioxidant and anti-cancer activities. Brazil is in the second place, with special interest for anti-tumor studies. Given the identification of the Brazilian groups that exploit the species it is possible to mediate partnerships and cooperation aiming to help on the implementing of the Program of Herbal medicines (phytotherapics) in Brazil.

Keywords: Phyllanthus niruri, phytotherapics, technological forecasting.

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2155 A Novel Approach for Beneficiation and Dewatering of Coal Fines for Indian Coal Preparation Plant

Authors: K.K. Sharma, K.M.K. Sinha, T.G. Charan, D.D. Haldar

Abstract:

An attempt has been made to beneficiate the Indian coking coal fines by a combination of Spiral, flotation and Oleo Flotation processes. Beneficiation studies were also carried out on - 0.5mm coal fines using flotation and oleo flotation by splitting at size 0.063mm.Size fraction of 0.5mm-0.063mm and -0.063mm size were treated in flotation and Oleo flotation respectively. The washability studies on the fraction 3-0.5 mm indicated that good separation may be achieved when it is fed in a spiral. Combined product of Spiral, Flotation and Oleo Flotation has given a significant yield at acceptable ash%. Studies were also conducted to see the dewatering of combined product by batch type centrifuge. It may further be suggested that combination of different processes may be used to treat the -3 mm fraction in an integrated manner to achieve the yield at the desired ash level. The treatment of the 3/1 mm -0.5 mm size fraction by spiral,-0.5-0.63 mm by conventional froth flotation and - 0.063 fractions by oleo flotation may provide a complete solution of beneficiation and dewatering of coal fines, and can effectively address the environmental problems caused by coal fines.

Keywords: coal fines, dewatering, environment, flotation, oleoflotation, spiral

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2154 CAD/CAM Algorithms for 3D Woven Multilayer Textile Structures

Authors: Martin A. Smith, Xiaogang Chen

Abstract:

This paper proposes new algorithms for the computeraided design and manufacture (CAD/CAM) of 3D woven multi-layer textile structures. Existing commercial CAD/CAM systems are often restricted to the design and manufacture of 2D weaves. Those CAD/CAM systems that do support the design and manufacture of 3D multi-layer weaves are often limited to manual editing of design paper grids on the computer display and weave retrieval from stored archives. This complex design activity is time-consuming, tedious and error-prone and requires considerable experience and skill of a technical weaver. Recent research reported in the literature has addressed some of the shortcomings of commercial 3D multi-layer weave CAD/CAM systems. However, earlier research results have shown the need for further work on weave specification, weave generation, yarn path editing and layer binding. Analysis of 3D multi-layer weaves in this research has led to the design and development of efficient and robust algorithms for the CAD/CAM of 3D woven multi-layer textile structures. The resulting algorithmically generated weave designs can be used as a basis for lifting plans that can be loaded onto looms equipped with electronic shedding mechanisms for the CAM of 3D woven multi-layer textile structures.

Keywords: CAD/CAM, Multi-layer, Textile, Weave.

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2153 Study on the Application of Lime to Improve the Rheological Properties of Polymer Modified Bitumen

Authors: A. Chegenizadeh, M. Keramatikerman, H. Nikraz

Abstract:

Bitumen is one of the most applicable materials in pavement engineering. It is a binding material with unique viscoelastic properties, especially when it mixes with polymer. In this study, to figure out the viscoelastic behaviour of the polymer modified with bitumen (PMB), a series of dynamic shearing rheological (DSR) tests were conducted. Four percentages of lime (i.e. 1%, 2%, 4% and 5%) were mixed with PMB and tested under four different temperatures including 64ºC, 70ºC, 76ºC and 82ºC. The results indicated that complex shearing modulus (G*) increased by increasing the frequency due to raised resistance against deformation. The phase angle (δ) showed a decreasing trend by incrementing the frequency. The addition of lime percentages increased the complex modulus value and declined phase angle parameter. Increasing the temperature decreased the complex modulus and increased the phase angle until 70ºC. The decreasing trend of rutting factor with increasing temperature revealed that rutting factor improved by the addition of the lime to the PMB.

Keywords: Rheological properties, DSR test, polymer mixed with bitumen, complex modulus, lime.

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2152 Realignment of f-actin Cytoskeleton in Osteocytes after Mechanical Loading

Authors: R. S. A. Nesbitt, J. Macione, E. Babollah, B. Adu-baffour, S. P. Kotha

Abstract:

F-actin fibrils are the cytoskeleton of osteocytes. They react in a dynamic manner to mechanical loading, and strength and reposition their efforts to reinforce the cells structure. We hypothesize that f-actin is temporarly disrupted after loading and repolymerizes in a new orientation to oppose the applied load. In vitro studies are conducted to determine f-actin disruption after varying mechanical stimulus parameters that are known to affect bone formation. Results indicate that the f-actin cytoskeleton is disrupted in vitro as a function of applied mechanical stimulus parameters and that the f-actin bundles reassemble after loading induced disruption within 3 minutes after cessation of loading. The disruption of the factin cytoskeleton depends on the magnitude of stretch, the numbers of loading cycles, frequency, the insertion of rest between loading cycles and extracellular calcium. In vivo studies also demonstrate disruption of the f-actin cytoskeleton in cells embedded in the bone matrix immediately after mechanical loading. These studies suggest that adaptation of the f-actin fiber bundles of the cytoskeleton in response to applied loads occurs by disruption and subsequent repolymerization.

Keywords: Mechanical loading of osteocytes, f-actin cytoskeleton, disruption, re-polymerization.

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2151 Identification of Binding Proteins That Interact with BVDV E2 Protein in Bovine Trophoblast Cell

Authors: Yan Ren, Fei Guo, Jun Qiao, Shengwei Hu, Hui Zhang, Yuanzhi Wang, Pengyan Wang, Jinliang Sheng, Xinli Gu, Xiaojun Liu, Chuangfu Chen

Abstract:

Bovine viral diarrhea virus (BVDV) can cause lifelong persistent infection. One reason for the phenomena is attributed to BVDV infection to placenta tissue. However the mechanisms that BVDV invades into placenta tissue remain unclear. To clarify the molecular mechanisms, we investigated the possible means that BVDV entered into bovine trophoblast cells (TPC). Yeast two-hybrid system was used to identify proteins extracted from TPC, which interact with BVDV envelope glycoprotein E2. A PGbkt7-E2 yeast expression vector and TPC cDNA library were constructed. Through two rounds of screening, three positive clones were identified. Sequencing analysis indicated that all the three positive clones encoded the same protein clathrin. Physical interaction between clathrin and BVDV E2 protein was further confirmed by coimmunoprecipitation experiments. This result suggested that the clathrin might play a critical role in the process of BVDV entry into placenta tissue and might be a novel antiviral target for preventing BVDV infection.

Keywords: Bovine viral diarrhea virus, clathrin, glycoprotein E2, yeast two-hybrid system.

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2150 Stress Intensity Factors for Plates with Collinear and Non-Aligned Straight Cracks

Authors: Surendran M, Palani G. S, Nagesh R. Iyer

Abstract:

Multi-site damage (MSD) has been a challenge to aircraft, civil and power plant structures. In real life components are subjected to cracking at many vulnerable locations such as the bolt holes. However, we do not consider for the presence of multiple cracks. Unlike components with a single crack, these components are difficult to predict. When two cracks approach one another, their stress fields influence each other and produce enhancing or shielding effect depending on the position of the cracks. In the present study, numerical studies on fracture analysis have been conducted by using the developed code based on the modified virtual crack closure integral (MVCCI) technique and finite element analysis (FEA) software ABAQUS for computing SIF of plates with multiple cracks. Various parametric studies have been carried out and the results have been compared with literature where ever available and also with the solution, obtained by using ABAQUS. By conducting extensive numerical studies expressions for SIF have been obtained for collinear cracks and non-aligned cracks.

Keywords: Crack interaction, Fracture mechanics, Multiple site damage, stress intensity factor, collinear cracks, non-aligned cracks.

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2149 Applying the Crystal Model Approach on Light Nuclei for Calculating Radii and Density Distribution

Authors: A. Amar

Abstract:

A new model namely, the crystal model, has been modified to calculate radius and density distribution of light nuclei up to 8Be. The crystal model has been modified according to solid state physics which uses the analogy between nucleon distribution and atoms distribution in the crystal. The model has analytical analysis to calculate the radius where the density distribution of light nuclei has been obtained from the analogy of crystal lattice. The distribution of nucleons over crystal has been discussed in general form. The equation used to calculate binding energy was taken from the solid-state model of repulsive and attractive force. The numbers of the protons were taken to control repulsive force where the atomic number was responsible for the attractive force. The parameter has been calculated from the crystal model was found to be proportional to the radius of the nucleus. The density distribution of light nuclei was taken as a summation of two clusters distribution as in 6Li=alpha+deuteron configuration. A test has been done on the data obtained for radius and density distribution using double folding for d+6,7Li with M3Y nucleon-nucleon interaction. Good agreement has been obtained for both radius and density distribution of light nuclei. The model failed to calculate the radius of 9Be, so modifications should be done to overcome discrepancy.

Keywords: nuclear lattice, crystal model, light nuclei, nuclear density distributions

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2148 Case Studies in Three Domains of Learning: Cognitive, Affective, Psychomotor

Authors: Zeinabsadat Haghshenas

Abstract:

Bloom’s Taxonomy has been changed during the years. The idea of this writing is about the revision that has happened in both facts and terms. It also contains case studies of using cognitive Bloom’s taxonomy in teaching geometric solids to the secondary school students, affective objectives in a creative workshop for adults and psychomotor objectives in fixing a malfunctioned refrigerator lamp. There is also pointed to the important role of classification objectives in adult education as a way to prevent memory loss.

Keywords: Adult education, affective domain, cognitive domain, memory loss, psychomotor domain.

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2147 Free and Open Source Licences, Software Programmers, and the Social Norm of Reciprocity

Authors: Luke McDonagh

Abstract:

Over the past three decades, free and open source software (FOSS) programmers have developed new, innovative and legally binding licences that have in turn enabled the creation of innumerable pieces of everyday software, including Linux, Mozilla Firefox and Open Office. That FOSS has been highly successful in competing with 'closed source software' (e.g. Microsoft Office) is now undeniable, but in noting this success, it is important to examine in detail why this system of FOSS has been so successful. One key reason is the existence of networks or communities of programmers, who are bound together by a key shared social norm of 'reciprocity'. At the same time, these FOSS networks are not unitary – they are highly diverse and there are large divergences of opinion between members regarding which licences are generally preferable: some members favour the flexible ‘free’ or 'no copyleft' licences, such as BSD and MIT, while other members favour the ‘strong open’ or 'strong copyleft' licences such as GPL. This paper argues that without both the existence of the shared norm of reciprocity and the diversity of licences, it is unlikely that the innovative legal framework provided by FOSS would have succeeded to the extent that it has.

Keywords: Open source, software, licences, reciprocity, networks.

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2146 Development of an Adhesive from Prosopis africana Seed Endosperm (Okpeyi)

Authors: Nwangwu Florence Chinyere, Ene Rosemary Ndidiamaka

Abstract:

This research work is an experimental study, through development of an adhesive from Prosopis africana endosperm. The prosopis seed for this work were obtained from Enugu State in the South East part of Nigeria. The seeds were prepared by separating the endosperm from the seed coat and cotyledon. Three methods were used to separate them, which are acidic method, roasting method and boiling method. 20g of seed were treated with different concentrations (25, 40, 55, 70, and 85% w/w) at 100°C and constant time (30 minutes), under continuous stirring with magnetic stirrer. Also 20g of seed were treated with sulphuric acid of concentrations 40% w/w at 100°C with different time (10, 15, 20, 25, 30 minutes), under continuous stirring with magnetic stirrer. Finally, 20g of seed were treated with sulphuric acid of concentrations 40% w/w at different temperature (20°C, 40°C, 60°C, 80°C, and 100°C) with constant time (30 minutes), under continuous stirring with magnetic stirrer. The whole endosperm extracted was adhesive. The physical properties of the adhesive were determined (appearance, odour, taste, solubility, pH, size, and binding strength). The percentage of the adhesive yield makes the commercialization of the seed in Nigeria possible and profitable. The very high viscosity attained at low concentrations makes prosopis adhesive an excellent thickener in the food industry.

Keywords: Endosperm, adhesive, ethanol, Prosopis africana seed.

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2145 STEP Implementation on Turn-mill Manufacturing Environment

Authors: Ahmad Majdi Bin Abdul-Rani, Mesfin Gizaw, Yusri Yusof

Abstract:

Researches related to standard product model and development of neutral manufacturing interfaces for numerical control machines becomes a significant topic since the last 25 years. In this paper, a detail description of STEP implementation on turnmill manufacturing has been discussed. It shows requirements of information contents from ISO14649 data model. It covers to describe the design of STEP-NC framework applicable to turn-mill manufacturing. In the framework, EXPRESS-G and UML modeling tools are used to depict the information contents of the system and established the bases of information model requirement. A product and manufacturing data model applicable for STEP compliant manufacturing. The next generation turn-mill operations requirements have been represented by a UML diagram. An object oriented classes of ISO1449 has been developed on Visual Basic dot NET platform for binding the static information model represented by the UML diagram. An architect of the proposed system implementation has been given on the bases of the design and manufacturing module of STEP-NC interface established. Finally, a part 21 file process plan generated for an illustration of turn-mill components.

Keywords: CAPP, ISO14649, Product modeling, STEP-NC

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2144 Linguistic Phenomena in Men and Women - TOT, FOK, Verbal Fluency

Authors: Ewa Szepietowska, Barbara Gawda, Agnieszka Gawda

Abstract:

The aim of this study is to describe the differences between women and men in the phenomena of feeling of knowing/know (FOK), tip of the tongue (TOT), and verbal fluency. Two studies are presented. The first included a group of 60 participants and focused on the analysis of FOK and TOT in men and women. The second study described the performance of 302 participants in verbal fluency tasks. Both studies showed that sex is not a significant predictor of linguistic abilities. Rather, the main factors influencing one’s linguistic ability were Vocabulary and education. This study enriches the knowledge on mechanisms of memory and verbal production.

Keywords: Feeling of knowing, Tip of the tongue, Verbal fluency, Sex differences.

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2143 A Method under Uncertain Information for the Selection of Students in Interdisciplinary Studies

Authors: José M. Merigó, Pilar López-Jurado, M.Carmen Gracia, Montserrat Casanovas

Abstract:

We present a method for the selection of students in interdisciplinary studies based on the hybrid averaging operator. We assume that the available information given in the problem is uncertain so it is necessary to use interval numbers. Therefore, we suggest a new type of hybrid aggregation called uncertain induced generalized hybrid averaging (UIGHA) operator. It is an aggregation operator that considers the weighted average (WA) and the ordered weighted averaging (OWA) operator in the same formulation. Therefore, we are able to consider the degree of optimism of the decision maker and grades of importance in the same approach. By using interval numbers, we are able to represent the information considering the best and worst possible results so the decision maker gets a more complete view of the decision problem. We develop an illustrative example of the proposed scheme in the selection of students in interdisciplinary studies. We see that with the use of the UIGHA operator we get a more complete representation of the selection problem. Then, the decision maker is able to consider a wide range of alternatives depending on his interests. We also show other potential applications that could be used by using the UIGHA operator in educational problems about selection of different types of resources such as students, professors, etc.

Keywords: Decision making, Selection of students, Uncertainty, Aggregation operators.

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2142 Measuring Pressure Wave Velocity in a Hydraulic System

Authors: Lari Kela, Pekka Vähäoja

Abstract:

Pressure wave velocity in a hydraulic system was determined using piezo pressure sensors without removing fluid from the system. The measurements were carried out in a low pressure range (0.2 – 6 bar) and the results were compared with the results of other studies. This method is not as accurate as measurement with separate measurement equipment, but the fluid is in the actual machine the whole time and the effect of air is taken into consideration if air is present in the system. The amount of air is estimated by calculations and comparisons between other studies. This measurement equipment can also be installed in an existing machine and it can be programmed so that it measures in real time. Thus, it could be used e.g. to control dampers.

Keywords: Bulk modulus, pressure wave, sound velocity.

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2141 Effect of Chlorophyll Concentration Variations from Extract of Papaya Leaves on Dye-Sensitized Solar Cell

Authors: Eka Maulana, Sholeh Hadi Pramono, Dody Fanditya, M. Julius

Abstract:

In this paper, extract of papaya leaves are used as a natural dye and combined by variations of solvent concentration applied on DSSC (Dye-Sensitized Solar Cell). Indonesian geographic located on the equator line occasions the magnitude of the potential to develop organic solar cells made from extracts of chlorophyll as a substitute for inorganic materials or synthetic dye on DSSC material. Dye serves as absorbing photons which are then converted into electrical energy. A conductive coated glass layer called TCO (Transparent Conductive Oxide) is used as a substrate of electrode. TiO2 nanoparticles as binding dye molecules, redox couple iodide/ tri-iodide as the electrolyte and carbon as the counter electrode in the DSSC are used. TiO2 nanoparticles, organic dyes, electrolytes, and counter electrode are arranged and combined with the layered structure of the photo-catalyst absorption layer. Dye absorption measurements using a spectrophotometer at 400-800 nm light spectrum produces a total amount of chlorophyll 80.076 mg/l. The test cell at 7 watt LED light with 5000 lux luminescence was obtained Voc and Isc of 235.5 mV and 14 μA, respectively.

Keywords: DSSC (Dye-Sensitized Solar Cell), natural dye, chlorophyll, absorption.

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2140 Gamification as a Tool for Influencing Customers' Behaviour

Authors: B. Zatwarnicka-Madura

Abstract:

The objective of the article was to identify the impacts of gamification on customers' behaviour. The most important applications of games in marketing and mechanisms of gamification are presented in the article. A detailed analysis of the influence of gamification on customers using two brands, Foursquare and Nike, was also presented. Research studies using auditory survey methods were carried out among 176 young respondents, who are potential targets of gamification. The studies confirmed a huge participation of young people in customer loyalty programs with relatively low participation in other gamificationbased marketing activities. The research findings clearly indicate that gamification mechanisms are the most attractive.

Keywords: Customer loyalty, games, gamification, social aspects.

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2139 Studies on Lucrative Design of Waste Heat Recovery System for Air Conditioners

Authors: Ashwin Bala, K. Panthalaraja Kumaran, S. Prithviraj, R. Pradeep, J. Udhayakumar, S. Ajith

Abstract:

In this paper comprehensive studies have been carried out for the design optimization of a waste heat recovery system for effectively utilizing the domestic air conditioner heat energy for producing hot water. Numerical studies have been carried for the geometry optimization of a waste heat recovery system for domestic air conditioners. Numerical computations have been carried out using a validated 2d pressure based, unsteady, 2nd-order implicit, SST k-ω turbulence model. In the numerical study, a fully implicit finite volume scheme of the compressible, Reynolds-Averaged, Navier- Stokes equations is employed. At identical inflow and boundary conditions various geometries were tried and effort has been taken for proposing the best design criteria. Several combinations of pipe line shapes viz., straight and spiral with different number of coils for the radiator have been attempted and accordingly the design criteria has been proposed for the waste heat recovery system design. We have concluded that, within the given envelope, the geometry optimization is a meaningful objective for getting better performance of waste heat recovery system for air conditioners.

Keywords: Air-conditioning system, Energy conversion system, Hot water production from waste heat, Waste heat recovery system.

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2138 Development of Molecular Imprinted Polymers (MIPs) for the Selective Removal of Carbamazepine from Aqueous Solution

Authors: Bianca Schweiger, Lucile Bahnweg, Barbara Palm, Ute Steinfeld

Abstract:

The occurrence and removal of trace organic contaminants in the aquatic environment has become a focus of environmental concern. For the selective removal of carbamazepine from loaded waters molecularly imprinted polymers (MIPs) were synthesized with carbamazepine as template. Parameters varied were the type of monomer, crosslinker, and porogen, the ratio of starting materials, and the synthesis temperature. Best results were obtained with a template to crosslinker ratio of 1:20, toluene as porogen, and methacrylic acid (MAA) as monomer. MIPs were then capable to recover carbamazepine by 93% from a 10-5 M landfill leachate solution containing also caffeine and salicylic acid. By comparison, carbamazepine recoveries of 75% were achieved using a nonimprinted polymer (NIP) synthesized under the same conditions, but without template. In landfill leachate containing solutions carbamazepine was adsorbed by 93-96% compared with an uptake of 73% by activated carbon. The best solvent for desorption was acetonitrile, with which the amount of solvent necessary and dilution with water was tested. Selected MIPs were tested for their reusability and showed good results for at least five cycles. Adsorption isotherms were prepared with carbamazepine solutions in the concentration range of 0.01 M to 5*10-6 M. The heterogeneity index showed a more homogenous binding site distribution.

Keywords: Carbamazepine, landfill leachate, removal, reuse

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2137 Barriers to Knowledge Management: A Theoretical Framework and a Review of Industrial Cases

Authors: Chihab BenMoussa

Abstract:

Firms have invested heavily in knowledge management (KM) with the aim to build a knowledge capability and use it to achieve a competitive advantage. Research has shown, however, that not all knowledge management projects succeed. Some studies report that about 84% of knowledge management projects fail. This paper has integrated studies on the impediments to knowledge management into a theoretical framework. Based on this framework, five cases documenting failed KM initiatives were analysed. The analysis gave us a clear picture about why certain KM projects fail. The high failure rate of KM can be explained by the gaps that exist between users and management in terms of KM perceptions and objectives

Keywords: Knowledge management, barriers to knowledge management, Knowledge-gaps, supply-driven approach to knowledge management.

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2136 Numerical Studies on the Performance of Finned-Tube Heat Exchanger

Authors: Praveen Kumar S P, Bong-Su Sin, Kwon-Hee Lee

Abstract:

Finned-tube heat exchangers are predominantly used in space conditioning systems, as well as other applications requiring heat exchange between two fluids. The design of finned-tube heat exchangers requires the selection of over a dozen design parameters by the designer such as tube pitch, tube diameter, tube thickness, etc… Finned-tube heat exchangers are common devices; however, their performance characteristics are complicated. In this paper numerical studies have been carried out to analyze the performances of finned tube heat exchanger (without fins considered for experimental purpose) by predicting the characteristics of temperature difference and pressure drop. In this study, a design considering 5 design variables and also maximizing the temperature difference and pressure drop was suggested by applying DOE. During this process, L18 orthogonal array was adopted. Parametric analytical studies have been carried out using ANOVA to determine the relative importance of each variable with respect to the temperature difference and the pressure drop. Following the results, the final design was suggested by predicting the optimum design therefore confirming the optimized condition.

Keywords: Heat Exchanger, Fluid Analysis, Heat Transfer, Design of Experiment (DOE), Analysis of Variance (ANOVA).

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2135 Innovativeness of the Furniture Enterprises in Bulgaria

Authors: Radostina Popova

Abstract:

The paper presents an analysis of the innovation performance of small and medium-sized furniture enterprises in Bulgaria, accounting for over 97% of the companies in the sector. It contains advanced features of innovation in enterprises, specific features of the furniture industry in Bulgaria and analysis of the results of studies on the topic. The results from studies of three successive periods - 2006-2008; 2008-2010; 2010-2012, during which were studied 594 small and medium-sized furniture enterprises. There are commonly used in the EU definitions and indicators (European Commission, OECD, Oslo Manual), which allows for the comparability of results.

Keywords: Innovation activity, competitiveness of innovation, furniture enterprises in Bulgaria.

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2134 Can a Development Bank Improve the Governance of Investee Companies? Evidence from BNDES in Brazil

Authors: Andre Luiz Carvalhal da Silva, Fernanda Farah de Abreu Zorman

Abstract:

There are many studies in the literature on institutional investors- efforts to improve corporate governance, generally focused on the role of pension funds and private equity firms. There are only a few studies that analyze the influence of development banks in the governance of investee companies. The objective of this research is to examine the role of the Brazilian Development Bank (BNDES) in the governance of listed companies. Our analysis provides evidence that companies in which BNDES is a shareholder have better governance.

Keywords: BNDES, corporate governance, development banks, institutional investors.

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2133 Wasp Venom Peptides may play a role in the Pathogenesis of Acute Disseminated Encephalomyelitis in Humans: A Structural Similarity Analysis

Authors: Permphan Dharmasaroja

Abstract:

Acute disseminated encephalomyelitis (ADEM) has been reported to develop after a hymenoptera sting, but its pathogenesis is not known in detail. Myelin basic protein (MBP)- specific T cells have been detected in the blood of patients with ADEM, and a proportion of these patients develop multiple sclerosis (MS). In an attempt to understand the mechanisms underlying ADEM, molecular mimicry between hymenoptera venom peptides and the human immunodominant MBP peptide was scrutinized, based on the sequence and structural similarities, whether it was the root of the disease. The results suggest that the three wasp venom peptides have low sequence homology with the human immunodominant MBP residues 85-99. Structural similarity analysis among the three venom peptides and the MS-related HLA-DR2b (DRA, DRB1*1501)-associated immunodominant MHC binding/TCR contact residues 88-93, VVHFFK showed that hyaluronidase residues 7-12, phospholipase A1 residues 98-103, and antigen 5 residues 109-114 showed a high degree of similarity 83.3%, 100%, and 83.3% respectively. In conclusion, some wasp venom peptides, particularly phospholipase A1, may potentially act as the molecular motifs of the human 3HLA-DR2b-associated immunodominant MBP88-93, and possibly present a mechanism for induction of wasp sting-associated ADEM.

Keywords: central nervous system, Hymenoptera, myelin basicprotein, molecular mimicry.

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2132 Preliminary Study on Determining Stem Diameter Variations of Sympodial Orchid

Authors: N.M Khairi, M.I. Naimah, M.S.B. Shah Rizam, M.T. Nooritawati, Z.A. Husna

Abstract:

Changes in stem diameter of orchid plants were investigated in a control growing climate. Previous studies have focused on stem diameter in relation to plant water on terrestrial plants in order to schedule the irrigation. The objective of this work was to evaluate the ability of the strain gauges to capture changes in the epiphytes plant stem. Experiments were carried out by using the sympodial orchid, Dendrobium Sonia in a stressed condition. From the findings, the sensor can detect changes in the plant stem and the result can easily be used as a reference for further studies for the development of a proper watering system.

Keywords: Strain gauge, stem diameter, Dendrobium Sonia, epiphyte, terrestrial

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2131 Modal Analysis of Power System with a Microgrid

Authors: Burak Yildirim, Muhsin Tunay Gençoğlu

Abstract:

A microgrid (MG) is a small power grid composed of localized medium or low level power generation, storage systems, and loads. In this paper, the effects of a MG on power systems voltage stability are shown. The MG model, designed to demonstrate the effects of the MG, was applied to the IEEE 14 bus power system which is widely used in power system stability studies. Eigenvalue and modal analysis methods were used in simulation studies. In the study results, it is seen that MGs affect system voltage stability positively by increasing system voltage instability limit value for buses of a power system in which MG are placed.

Keywords: Eigenvalue analysis, microgrid, modal analysis, voltage stability.

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2130 Primary School Principals in Turkey: Their Working Conditions and Professional Profiles

Authors: Ali I. Gumuseli

Abstract:

In order to achieve effective management, the professional and individual characteristics and qualifications of school principals and their system-oriented perception is very important. Therefore, it is necessary to conduct regular comprehensive studies into the profiles of school principals. The purpose of this study is to determine the perceptions of primary school principals about their working conditions and to present their professional profiles. The questionnaire was distributed to 1475 respondents and 1428 valid questionnaires were evaluated. The results of the research were discussed and compared to other similar studies.Keywordseducation, education management, primary school principal, principals profiles

Keywords: education, education management, primary school principal, principals profiles

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2129 Selection of Relevant Servers in Distributed Information Retrieval System

Authors: Benhamouda Sara, Guezouli Larbi

Abstract:

Nowadays, the dissemination of information touches the distributed world, where selecting the relevant servers to a user request is an important problem in distributed information retrieval. During the last decade, several research studies on this issue have been launched to find optimal solutions and many approaches of collection selection have been proposed. In this paper, we propose a new collection selection approach that takes into consideration the number of documents in a collection that contains terms of the query and the weights of those terms in these documents. We tested our method and our studies show that this technique can compete with other state-of-the-art algorithms that we choose to test the performance of our approach.

Keywords: Distributed information retrieval, relevance, server selection, collection selection.

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2128 The Use of Hydrocolloid Dressing in the Management of Open Wounds in Big Cats

Authors: Catherine Portelli

Abstract:

Felines, such as Panthera tigris, Panthera leo and Puma concolor, have become common residents in animal parks and zoos. They often sustain injuries from other felines within the same, or adjacent enclosures and from playing with items of enrichment and structures of the enclosure itself. These open wounds, and their treatments, are often challenging in veterinary practice, where feline-specific studies are lacking. This study is based on the author’s clinical experience gained while working at local animal parks in the past five years, and current evidence of hydrocolloid dressing applied to other species. Hydrocolloid dressing is used for secondary healing of chronic and acute wounds, where there is a considerable amount of tissue loss. The patients included in this study were sedated using medetomidine and ketamine every three to four days, for wound treatment and bandage change. Comparative studies of different techniques of open wound management will improve the healing process of exotic felines in the future by decreasing the time of recovery and incidence of other complications. Such studies will also aid with treatment of injuries sustained in wild felines, such as foot hold trap and bite wounds, found in natural conservation areas and wild animal sanctuaries.

Keywords: Felines, hydrocolloid dressing, open wound, secondary healing.

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2127 Depth Estimation in DNN Using Stereo Thermal Image Pairs

Authors: Ahmet Faruk Akyuz, Hasan Sakir Bilge

Abstract:

Depth estimation using stereo images is a challenging problem in computer vision. Many different studies have been carried out to solve this problem. With advancing machine learning, tackling this problem is often done with neural network-based solutions. The images used in these studies are mostly in the visible spectrum. However, the need to use the Infrared (IR) spectrum for depth estimation has emerged because it gives better results than visible spectra in some conditions. At this point, we recommend using thermal-thermal (IR) image pairs for depth estimation. In this study, we used two well-known networks (PSMNet, FADNet) with minor modifications to demonstrate the viability of this idea.

Keywords: thermal stereo matching, depth estimation, deep neural networks, CNN

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