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1783 Computational Analysis of Potential Inhibitors Selected Based On Structural Similarity for the Src SH2 Domain
Authors: W. P. Hu, J. V. Kumar, Jeffrey J. P. Tsai
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The inhibition of SH2 domain regulated protein-protein interactions is an attractive target for developing an effective chemotherapeutic approach in the treatment of disease. Molecular simulation is a useful tool for developing new drugs and for studying molecular recognition. In this study, we searched potential drug compounds for the inhibition of SH2 domain by performing structural similarity search in PubChem Compound Database. A total of 37 compounds were screened from the database, and then we used the LibDock docking program to evaluate the inhibition effect. The best three compounds (AP22408, CID 71463546 and CID 9917321) were chosen for MD simulations after the LibDock docking. Our results show that the compound CID 9917321 can produce a more stable protein-ligand complex compared to other two currently known inhibitors of Src SH2 domain. The compound CID 9917321 may be useful for the inhibition of SH2 domain based on these computational results. Subsequently experiments are needed to verify the effect of compound CID 9917321 on the SH2 domain in the future studies.
Keywords: Nonpeptide inhibitor, Src SH2 domain, LibDock, molecular dynamics simulation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20781782 Development of a Portable Welding Robot with EtherCAT Interface
Authors: Juyi Park, Sang-Bum Lee, Jin-Wook Kim, Ji-Yoon Kim, Jung-Min Kim, Hee-Hwan Park, Jae-Won Seo, Gye-Hyung Kang, Soo-Ho Kim
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This paper presents a portable robot that is to use for welding process in shipbuilding yard. It has six degree of freedom and 3kg payload capability. Its weight is 21.5kg so that human workers can carry it to the work place. Its body mainly made of magnesium alloy and aluminum alloy for few parts that require high strength. Since the distance between robot and controller should be 50m at most, the robot controller controls the robot through EtherCAT. RTX and KPA are used for real time EtherCAT control on Windows XP. The performance of the developed robot was satisfactory, in welding of U type cell in shipbuilding yard.Keywords: Portable welding robot, Shipbuilding, EtherCAT
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19631781 Finite Element Approach to Evaluate Time Dependent Shear Behavior of Connections in Hybrid Steel-PC Girder under Sustained Loading
Authors: Mohammad Najmol Haque, Takeshi Maki, Jun Sasaki
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Headed stud shear connections are widely used in the junction or embedded zone of hybrid girder to achieve whole composite action with continuity that can sustain steel-concrete interfacial tensile and shear forces. In Japan, Japan Road Association (JRA) specifications are used for hybrid girder design that utilizes very low level of stud capacity than those of American Institute of Steel Construction (AISC) specifications, Japan Society of Civil Engineers (JSCE) specifications and EURO code. As low design shear strength is considered in design of connections, the time dependent shear behavior due to sustained external loading is not considered, even not fully studied. In this study, a finite element approach was used to evaluate the time dependent shear behavior for headed studs used as connections at the junction. This study clarified, how the sustained loading distinctively impacted on changing the interfacial shear of connections with time which was sensitive to lodging history, positions of flanges, neighboring studs, position of prestress bar and reinforcing bar, concrete strength, etc. and also identified a shear influence area. Stud strength was also confirmed through pushout tests. The outcome obtained from the study may provide an important basis and reference data in designing connections of hybrid girders with enhanced stud capacity with due consideration of their long-term shear behavior.
Keywords: Finite element approach, hybrid girder, headed stud shear connections, sustained loading, time dependent shear behavior.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 6291780 Enhance the Modeling of BLDC Motor Based on Fuzzy Logic
Authors: Murugan Marimuthu, Jeyabharath Rajaih
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This paper describes a simple way to control the speed of PMBLDC motor using Fuzzy logic control method. In the conventional PI controller the performance of the motor system is simulated and the speed is regulated by using PI controller. These methods used to improve the performance of PMSM drives, but in some cases at different operating conditions when the dynamics of the system also vary over time and it can change the reference speed, parameter variations and the load disturbance. The simulation is powered with the MATLAB program to get a reliable and flexible simulation. In order to highlight the effectiveness of the speed control method the FLC method is used. The proposed method targeted in achieving the improved dynamic performance and avoids the variations of the motor drive. This drive has high accuracy, robust operation from near zero to high speed. The effectiveness and flexibility of the individual techniques of the speed control method will be thoroughly discussed for merits and demerits and finally verified through simulation and experimental results for comparative analysis.Keywords: Hall position sensors, permanent magnet brushless DC motor, PI controller, Fuzzy Controller.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 17861779 Finite Volume Model to Study The Effect of Voltage Gated Ca2+ Channel on Cytosolic Calcium Advection Diffusion
Authors: Brajesh Kumar Jha, Neeru Adlakha, M. N. Mehta
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Mathematical and computational modeling of calcium signalling in nerve cells has produced considerable insights into how the cells contracts with other cells under the variation of biophysical and physiological parameters. The modeling of calcium signaling in astrocytes has become more sophisticated. The modeling effort has provided insight to understand the cell contraction. Main objective of this work is to study the effect of voltage gated (Operated) calcium channel (VOC) on calcium profile in the form of advection diffusion equation. A mathematical model is developed in the form of advection diffusion equation for the calcium profile. The model incorporates the important physiological parameter like diffusion coefficient etc. Appropriate boundary conditions have been framed. Finite volume method is employed to solve the problem. A program has been developed using in MATLAB 7.5 for the entire problem and simulated on an AMD-Turion 32-bite machine to compute the numerical results.Keywords: Ca2+ Profile, Advection Diffusion, VOC, FVM.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 17811778 Determination of Critical Source Areas for Sediment Loss: Sarrath River Basin, Tunisia
Authors: Manel Mosbahi
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The risk of water erosion is one of the main environmental concerns in the southern Mediterranean regions. Thus, quantification of soil loss is an important issue for soil and water conservation managers. The objective of this paper is to examine the applicability of the Soil and Water Assessment Tool (SWAT) model in The Sarrath river catchment, North of Tunisia, and to identify the most vulnerable areas in order to help manager implement an effective management program. The spatial analysis of the results shows that 7 % of the catchment experiences very high erosion risk, in need for suitable conservation measures to be adopted on a priority basis. The spatial distribution of erosion risk classes estimated 3% high, 5,4% tolerable, and 84,6% low. Among the 27 delineated subcatchments only 4 sub-catchments are found to be under high and very high soil loss group, two sub-catchments fell under moderate soil loss group, whereas other sub-catchments are under low soil loss group.Keywords: Critical source areas, Erosion risk, SWAT model.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 14651777 Flexural Performance of the Sandwich Structures Having Aluminum Foam Core with Different Thicknesses
Authors: Emre Kara, Ahmet F. Geylan, Kadir Koç, Şura Karakuzu, Metehan Demir, Halil Aykul
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The structures obtained with the use of sandwich technologies combine low weight with high energy absorbing capacity and load carrying capacity. Hence, there is a growing and markedly interest in the use of sandwiches with aluminum foam core because of very good properties such as flexural rigidity and energy absorption capability. In the current investigation, the static threepoint bending tests were carried out on the sandwiches with aluminum foam core and glass fiber reinforced polymer (GFRP) skins at different values of support span distances aiming the analyses of their flexural performance. The influence of the core thickness and the GFRP skin type was reported in terms of peak load and energy absorption capacity. For this purpose, the skins with two different types of fabrics which have same thickness value and the aluminum foam core with two different thicknesses were bonded with a commercial polyurethane based flexible adhesive in order to combine the composite sandwich panels. The main results of the bending tests are: force-displacement curves, peak force values, absorbed energy, collapse mechanisms and the effect of the support span length and core thickness. The results of the experimental study showed that the sandwich with the skins made of S-Glass Woven fabrics and with the thicker foam core presented higher mechanical values such as load carrying and energy absorption capacities. The increment of the support span distance generated the decrease of the mechanical values for each type of panels, as expected, because of the inverse proportion between the force and span length. The most common failure types of the sandwiches are debonding of the lower skin and the core shear. The obtained results have particular importance for applications that require lightweight structures with a high capacity of energy dissipation, such as the transport industry (automotive, aerospace, shipbuilding and marine industry), where the problems of collision and crash have increased in the last years.Keywords: Aluminum foam, Composite panel, Flexure, Transport application.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 23291776 Web portal As A Knowledge Management System In The Universities
Authors: Marjan Mansourvar, Norizan Mohd Yasin
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The development of Web has affected different aspects of our lives, such as communication, sharing knowledge, searching for jobs, social activities, etc. The web portal as a gateway in the World Wide Web is a starting point for people who are connecting to the Internet. The web portal as the type of knowledge management system provides a rich space to share and search information as well as communication services like free email or content provision for the users. This research aims to discover the university needs to the web portal as a necessary tool for students in the universities to help them in getting the required information. A survey was conducted to gather students' requirements which can be incorporated in to portal to be developed.
Keywords: Knowledge, Knowledge management system, Knowledge sharing, web portal.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 18901775 Non-Sensitive Solutions in Multi-Objective Optimization of a Solar Photovoltaic/Thermal(PV/T) Air Collector
Authors: F. Sarhaddi, S. Farahat, M .A. Alavi, F. Sobhnamayan
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In this paper, an attempt has been made to obtain nonsensitive solutions in the multi-objective optimization of a photovoltaic/thermal (PV/T) air collector. The selected objective functions are overall energy efficiency and exergy efficiency. Improved thermal, electrical and exergy models are used to calculate the thermal and electrical parameters, overall energy efficiency, exergy components and exergy efficiency of a typical PV/T air collector. A computer simulation program is also developed. The results of numerical simulation are in good agreement with the experimental measurements noted in the previous literature. Finally, multi-objective optimization has been carried out under given climatic, operating and design parameters. The optimized ranges of inlet air velocity, duct depth and the objective functions in optimal Pareto front have been obtained. Furthermore, non-sensitive solutions from energy or exergy point of view in the results of multi-objective optimization have been shown.Keywords: Solar photovoltaic thermal (PV/T) air collector, Overall energy efficiency, Exergy efficiency, Multi-objectiveoptimization, Sensitivity analysis.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 21571774 Applicability of Diatom-Based Water Quality Assessment Indices in Dari Stream, Isparta- Turkey
Authors: Hasan Kalyoncu, Burcu Şerbetci
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Diatoms are an important group of aquatic ecosystems and diatom-based indices are increasingly becoming important tools for the assessment of ecological conditions in lotic systems. Although the studies are very limited about Turkish rivers, diatom indices were used for monitoring rivers in different basins. In the present study, we used OMNIDIA program for estimation of stream quality. Some indices have less sensitive (IDP, WAT, LOBO, GENRE, TID, CEE, PT), intermediate sensitivities (IDSE, DESCY, IPS, DI-CH, SLA, IDAP), the others higher sensitivities (SID, IBD, SHE, EPI-D). Among the investigated diatom communities, only a few taxa indicated alfa-mesosaprobity and polysaprobity. Most of the sites were characterized by a great relative contribution of eutraphent and tolerant ones as well as oligosaprobic and betamesosaprobic diatoms. In general, SID and IBD indices gave the best results. This study suggests that the structure of benthic diatom communities and diatom indices, especially SID, can be applied for monitoring rivers in Southern Turkey.
Keywords: Diatom, Darı stream, OMNIDIA, Turkey, Water quality.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 29211773 Developing Student Teachers to Be Professional Teachers
Authors: Suttipong Boonphadung
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Practicum placements are an critical factor for student teachers on Education Programs. How can student teachers become professionals? This study was to investigate problems, weakness and obstacles of practicum placements and develop guidelines for partnership in the practicum placements. In response to this issue, a partnership concept was implemented for developing student teachers into professionals. Data were collected through questionnaires on attitude toward problems, weaknesses, and obstacles of practicum placements of student teachers in Rajabhat universities and included focus group interviews. The research revealed that learning management, classroom management, curriculum, assessment and evaluation, classroom action research, and teacher demeanor are the important factors affecting the professional development of Education Program student teachers. Learning management plan and classroom management concerning instructional design, teaching technique, instructional media, and student behavior management are another important aspects influencing the professional development for student teachers.
Keywords: Developing student teacher, Partnership concepts, Professional teachers.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20441772 The Core and Shapley Function for Games on Augmenting Systems with a Coalition Structure
Authors: Fan-Yong Meng
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In this paper, we first introduce the model of games on augmenting systems with a coalition structure, which can be seen as an extension of games on augmenting systems. The core of games on augmenting systems with a coalition structure is defined, and an equivalent form is discussed. Meantime, the Shapley function for this type of games is given, and two axiomatic systems of the given Shapley function are researched. When the given games are quasi convex, the relationship between the core and the Shapley function is discussed, which does coincide as in classical case. Finally, a numerical example is given.
Keywords: Cooperative game, augmenting system, Shapley function, core.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 11951771 Effect of Inlet Valve Variable Timing in the Spark Ignition Engine on Achieving Greener Transport
Authors: Osama H. Ghazal, Yousef S. Najjar, Kutaeba J. AL-Khishali
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The current emission legislations and the large concern about the environment produced very numerous constraints on both governments and car manufacturers. Also the cost of energy increase means a reduction in fuel consumption must be met, without largely affecting the current engine production and performance. It is the intension to contribute towards the development and pursuing, among others on variable valve timing (VVT), for improving the engine performance. The investigation of the effect of (IVO) and (IVC) to optimize engine torque and volumetric efficiency for different engine speeds was considered. Power, BMEP and BSFC were calculated and presented to show the effect of varying inlet valve timing on them for all cases. A special program used to carry out the calculations. The analysis of the results shows that the reduction of 10% of (IVO) angle gave an improvement of around 1.3% in torque, BSFC, and volumetric efficiency, while a 10% decrease in (IVC) caused a 0.1% reduction in power, torque, and volumetric efficiency.
Keywords: Green transportation, inlet valve variable timing, performance, spark ignition engines.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 28621770 What Are the Factors Underlying the Differences between Young Saudi Women in Traditional Families That Choose to Conform to the Society Norms, and Young Saudi Women Who Do Not Conform?
Authors: Mai Al-Subaie
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This research suggests that women in traditional families of Saudi Arabia are divided into two groups, the one who conforms to the society and the new type of women that has been emerged due to the changing and development of the culture, who do not want to conform to the rules. The factors underlying the differences were explored by using a test and an interview. And that concluded some of the main factors that were a real affect of why some women still want to follow the society and traditional rules, and other want to break free.
Keywords: Conformity, Non-Conformity, Saudi Arabia, Women.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16851769 Travel Time Model for Cylinder Type Parking System
Authors: Jing Zhang, Jie Chen
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In this paper, we mainly analyze an automated parking system where the storage and retrieval requests are performed by a tower crane. In this parking system, the S/R crane which is located at the middle of the bottom of the cylinder parking area can rotate in both clockwise and counterclockwise and three kinds of movements can be done simultaneously. We develop some mathematical travel time models for the single command cycle under the random storage assignment using the characteristics of this system. Finally, we compare these travel models with discrete case and it is shown that these travel models display a good satisfactory performance.Keywords: Parking system, travel time model, tower crane.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 7931768 Construction of cDNALibrary and EST Analysis of Tenebriomolitorlarvae
Authors: JiEun Jeong, Se-Won Kang, Hee-Ju Hwang, Sung-Hwa Chae, Sang-Haeng Choi, Hong-SeogPark, YeonSoo Han, Bok-Reul Lee, Dae-Hyun Seog, Yong Seok Lee
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Tofurther advance research on immune-related genes from T. molitor, we constructed acDNA library and analyzed expressed sequence taq (EST) sequences from 1,056 clones. After removing vector sequence and quality checkingthrough thePhred program (trim_alt 0.05 (P-score>20), 1039 sequences were generated. The average length of insert was 792 bp. In addition, we identified 162 clusters, 167 contigs and 391 contigs after clustering and assembling process using a TGICL package. EST sequences were searchedagainst NCBI nr database by local BLAST (blastx, E1767 Numerical Analysis of Rapid Gas Decompression in Pure Nitrogen using 1D and 3D Transient Mathematical Models of Gas Flow in Pipes
Authors: Evgeniy Burlutskiy
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The paper presents a numerical investigation on the rapid gas decompression in pure nitrogen which is made by using the one-dimensional (1D) and three-dimensional (3D) mathematical models of transient compressible non-isothermal fluid flow in pipes. A 1D transient mathematical model of compressible thermal multicomponent fluid mixture flow in pipes is presented. The set of the mass, momentum and enthalpy conservation equations for gas phase is solved in the model. Thermo-physical properties of multicomponent gas mixture are calculated by solving the Equation of State (EOS) model. The Soave-Redlich-Kwong (SRK-EOS) model is chosen. This model is successfully validated on the experimental data [1] and shows a good agreement with measurements. A 3D transient mathematical model of compressible thermal single-component gas flow in pipes, which is built by using the CFD Fluent code (ANSYS), is presented in the paper. The set of unsteady Reynolds-averaged conservation equations for gas phase is solved. Thermo-physical properties of single-component gas are calculated by solving the Real Gas Equation of State (EOS) model. The simplest case of gas decompression in pure nitrogen is simulated using both 1D and 3D models. The ability of both models to simulate the process of rapid decompression with a high order of agreement with each other is tested. Both, 1D and 3D numerical results show a good agreement between each other. The numerical investigation shows that 3D CFD model is very helpful in order to validate 1D simulation results if the experimental data is absent or limited.Keywords: Mathematical model, Rapid Gas Decompression
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 22211766 Codon-optimized Carbonic Anhydrase from Dunaliella species: Expression and Characterization
Authors: Seung Pil Pack
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Carbonic anhydrases (CAs) has been focused as biological catalysis for CO2 sequestration process because it can catalyze the conversion of CO2 to bicarbonate. Here, codon-optimized sequence of α type-CA cloned from Duneliala species. (DsCAopt) was constructed, expressed, and characterized. The expression level in E. coli BL21(DE3) was better for codon-optimized DsCAopt than intact sequence of DsCAopt. DsCAopt enzyme shows high-stability at pH 7.6/10.0. In final, we demonstrated that in the Ca2+ solution, DsCAopt enzyme can catalyze well the conversion of CO2 to CaCO3, as the calcite form.Keywords: Carbonic anhydrase, Codon-optimization, Duneliala species, CO2 sequestration
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16461765 Post-Cracking Behaviour of High Strength Fiber Concrete Prediction and Validation
Authors: Andrejs Krasnikovs, Olga Kononova, Amjad Khabbaz, Edgar Machanovsky, Artur Machanovsky
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Fracture process in mechanically loaded steel fiber reinforced high-strength (SFRHSC) concrete is characterized by fibers bridging the crack providing resistance to its opening. Structural SFRHSC fracture model was created; material fracture process was modeled, based on single fiber pull-out laws, which were determined experimentally (for straight fibers, fibers with end hooks (Dramix), and corrugated fibers (Tabix)) as well as obtained numerically ( using FEM simulations). For this purpose experimental program was realized and pull-out force versus pull-out fiber length was obtained (for fibers embedded into concrete at different depth and under different angle). Model predictions were validated by 15x15x60cm prisms 4 point bending tests. Fracture surfaces analysis was realized for broken prisms with the goal to improve elaborated model assumptions. Optimal SFRHSC structures were recognized.Keywords: crack, fiber concrete, fiber pull-out, strength.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20991764 Food Safety Culture Paramount Than Traditional Food Safety System and Food Safety Culture in South African Food Industries
Authors: Oluwatosin A. Ijabadeniyi
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The fact that traditional food safety system in the absence of food safety culture is inadequate has recently become a cause of concern for food safety professionals and other stakeholders. Focusing on implementation of traditional food safety system i.e HACCP prerequisite program and HACCP without the presence of food safety culture in the food industry has led to the processing, marketing and distribution of contaminated foods. The results of this are regular out breaks of food borne illnesses and recalls of foods from retail outlets with serious consequences to the consumers and manufacturers alike. This article will consider the importance of food safety culture, the cases of outbreaks and recalls that occurred when companies did not make food safety culture a priority. Most importantly, the food safety cultures of some food industries in South Africa were assessed from responses to questionnaires from food safety/food industry professionals in Durban South Africa. The article was concluded by recommending that both food industry employees and employers alike take food safety culture seriously.Keywords: Good Manufacturing Practices (GMPs), food borne illnesses, food safety culture, food safety system, HACCP.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 32241763 Optimization of Fuel Consumption of a Bus used in City Line with Regulation of Driving Characteristics
Authors: Muammer Ozkan, Orkun Ozener, Irfan Yavasliol
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The fuel cost of the motor vehicle operating on its common route is an important part of the operating cost. Therefore, the importance of the fuel saving is increasing day by day. One of the parameters which improve fuel saving is the regulation of driving characteristics. The number and duration of stop is increased by the heavy traffic load. It is possible to improve the fuel saving with regulation of traffic flow and driving characteristics. The researches show that the regulation of the traffic flow decreases fuel consumption, but it is not enough to improve fuel saving without the regulation of driving characteristics. This study analyses the fuel consumption of two trips of city bus operating on its common route and determines the effect of traffic density and driving characteristics on fuel consumption. Finally it offers some suggestions about regulation of driving characteristics to improve the fuel saving. Fuel saving is determined according to the results obtained from simulation program. When experimental and simulation results are compared, it has been found that the fuel saving was reached up the to 40 percent ratios.Keywords: Fuel Consumption, Fuel Economy, Driving Characteristics, Optimization
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 18381762 Topping Failure Analysis of Anti-Dip Bedding Rock Slopes Subjected to Crest Loads
Authors: Chaoyi Sun, Congxin Chen, Yun Zheng, Kaizong Xia, Wei Zhang
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Crest loads are often encountered in hydropower, highway, open-pit and other engineering rock slopes. Toppling failure is one of the most common deformation failure types of anti-dip bedding rock slopes. Analysis on such failure of anti-dip bedding rock slopes subjected to crest loads has an important influence on engineering practice. Based on the step-by-step analysis approach proposed by Goodman and Bray, a geo-mechanical model was developed, and the related analysis approach was proposed for the toppling failure of anti-dip bedding rock slopes subjected to crest loads. Using the transfer coefficient method, a formulation was derived for calculating the residual thrust of slope toe and the support force required to meet the requirements of the slope stability under crest loads, which provided a scientific reference to design and support for such slopes. Through slope examples, the influence of crest loads on the residual thrust and sliding ratio coefficient was investigated for cases of different block widths and slope cut angles. The results show that there exists a critical block width for such slope. The influence of crest loads on the residual thrust is non-negligible when the block thickness is smaller than the critical value. Moreover, the influence of crest loads on the slope stability increases with the slope cut angle and the sliding ratio coefficient of anti-dip bedding rock slopes increases with the crest loads. Finally, the theoretical solutions and numerical simulations using Universal Distinct Element Code (UDEC) were compared, in which the consistent results show the applicability of both approaches.
Keywords: Anti-dip slopes, crest loads, stability analysis, toppling failure.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 9051761 Quantifying the Stability of Software Systems via Simulation in Dependency Networks
Authors: Weifeng Pan
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The stability of a software system is one of the most important quality attributes affecting the maintenance effort. Many techniques have been proposed to support the analysis of software stability at the architecture, file, and class level of software systems, but little effort has been made for that at the feature (i.e., method and attribute) level. And the assumptions the existing techniques based on always do not meet the practice to a certain degree. Considering that, in this paper, we present a novel metric, Stability of Software (SoS), to measure the stability of object-oriented software systems by software change propagation analysis using a simulation way in software dependency networks at feature level. The approach is evaluated by case studies on eight open source Java programs using different software structures (one employs design patterns versus one does not) for the same object-oriented program. The results of the case studies validate the effectiveness of the proposed metric. The approach has been fully automated by a tool written in Java.Keywords: Software stability, change propagation, design pattern, software maintenance, object-oriented (OO) software.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16781760 Single Event Transient Tolerance Analysis in 8051 Microprocessor Using Scan Chain
Authors: Jun Sung Go, Jong Kang Park, Jong Tae Kim
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As semi-conductor manufacturing technology evolves; the single event transient problem becomes more significant issue. Single event transient has a critical impact on both combinational and sequential logic circuits, so it is important to evaluate the soft error tolerance of the circuits at the design stage. In this paper, we present a soft error detecting simulation using scan chain. The simulation model generates a single event transient randomly in the circuit, and detects the soft error during the execution of the test patterns. We verified this model by inserting a scan chain in an 8051 microprocessor using 65 nm CMOS technology. While the test patterns generated by ATPG program are passing through the scan chain, we insert a single event transient and detect the number of soft errors per sub-module. The experiments show that the soft error rates per cell area of the SFR module is 277% larger than other modules.Keywords: Scan chain, single event transient, soft error, 8051 processor.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 14901759 Walking and Sustainable Urban Transportation
Authors: Khashayar Kashani Jou
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Walking as a type of non-motorized transportation has various social, economical and environmental privileges. Also, today different aspects of sustainable development have been emphasized and promotion of sustainable transportation modes has been considered according to this approach. Therefore, the objective of this research is exploring the circumstance of relationship between walking and sustainable urban transportation.For writing this article, the most important resources related to the traits of walking have been surveyed via a documentary method and after explaining the concept of sustainable transportation and its indicators, benefiting from the viewpoints of transportation experts of Tehran, as the capital and greatest city of Iran, different modes of urban transportation have been compared in proportion to each criterion and to each other and have been analyzed according to AHP method. The results of this study indicate that walking is the most sustainable mode of inner city transportation.Keywords: Walking, Non-motorized transportation, Sustainable transportation, AHP
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20341758 In-Plane Shear Tests of Prefabricated Masonry Panel System with Two-Component Polyurethane Adhesive
Authors: E. Fehling, P. Capewell
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In recent years, the importance of masonry glued by polyurethane adhesive has increased. In 2021, the Institute of Structural Engineering of the University of Kassel was commissioned to carry out quasi-static in-plane shear tests on prefabricated brick masonry panel systems with 2K PUR adhesive in order to investigate the load-bearing behavior during earthquakes. In addition to the usual measurement of deformations using displacement transducers, all tests were documented using an optical measuring system, which was used to determine the surface strains and deformations of the test walls. To compare the results with conventional mortar walls, additional reference tests were carried out on test specimens with thin-bed mortar joints. This article summarizes the results of the test program and provides a comparison between the load-bearing behavior of masonry bonded with polyurethane adhesive and thin-bed mortar in order to enable realistic non-linear modeling.
Keywords: Glued Masonry, in-plane tests, shear resistance, polyurethane adhesive.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 411757 Object Localization in Medical Images Using Genetic Algorithms
Authors: George Karkavitsas, Maria Rangoussi
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We present a genetic algorithm application to the problem of object registration (i.e., object detection, localization and recognition) in a class of medical images containing various types of blood cells. The genetic algorithm approach taken here is seen to be most appropriate for this type of image, due to the characteristics of the objects. Successful cell registration results on real life microscope images of blood cells show the potential of the proposed approach.
Keywords: Genetic algorithms, object registration, pattern recognition, blood cell microscope images.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19691756 The Shanghai Cooperation Organization: China's Grand Strategy in Central Asia
Authors: Mara Gubaidullina, Aigerim Yelibayeva
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The Shanghai Cooperation Organization is one of the successful outcomes of China's foreign policy since the end of the Cold war. The expansion of multilateral ties all over the world by dint of pursuing institutional strategies as SCO, identify China as a more constructive power. SCO became a new model of cooperation that was formed on remains of collapsed Soviet system, and predetermined China's geopolitical role in the region. As the fast developing effective regional mechanism, SCO today has more of external impact on the international system and forms a new type of interaction for promoting China's grand strategy of 'peaceful rise'.
Keywords: Central Asia, China's grand strategy, Shanghai Cooperation Organization.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20051755 Designing an Editorialization Environment for Repeatable Self-Correcting Exercises
Authors: M. Kobylanski, D. Buskulic, P.-H. Duron, D. Revuz, F. Ruggieri, E. Sandier, C. Tijus
Abstract:
In order to design a cooperative e-learning platform, we observed teams of Teacher [T], Computer Scientist [CS] and exerciser's programmer-designer [ED] cooperating for the conception of a self-correcting exercise, but without the use of such a device in order to catch the kind of interactions a useful platform might provide. To do so, we first run a task analysis on how T, CS and ED should be cooperating in order to achieve, at best, the task of creating and implementing self-directed, self-paced, repeatable self-correcting exercises (RSE) in the context of open educational resources. The formalization of the whole process was based on the “objectives, activities and evaluations” theory of educational task analysis. Second, using the resulting frame as a “how-to-do it” guide, we run a series of three contrasted Hackathon of RSE-production to collect data about the cooperative process that could be later used to design the collaborative e-learning platform. Third, we used two complementary methods to collect, to code and to analyze the adequate survey data: the directional flow of interaction among T-CS-ED experts holding a functional role, and the Means-End Problem Solving analysis. Fourth, we listed the set of derived recommendations useful for the design of the exerciser as a cooperative e-learning platform. Final recommendations underline the necessity of building (i) an ecosystem that allows to sustain teams of T-CS-ED experts, (ii) a data safety platform although offering accessibility and open discussion about the production of exercises with their resources and (iii) a good architecture allowing the inheritance of parts of the coding of any exercise already in the data base as well as fast implementation of new kinds of exercises along with their associated learning activities.
Keywords: Distance open educational resources, pedagogical alignment, self-correcting exercises, teacher’s involvement, team roles.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 5181754 Two Individual Genetic Algorithm
Authors: Younis R. Elhaddad, Aiman S.Gannous
Abstract:
The particular interests of this paper is to explore if the simple Genetic Algorithms (GA) starts with population of only two individuals and applying different crossover technique over these parents to produced 104 children, each one has different attributes inherited from their parents; is better than starting with population of 100 individuals; and using only one type crossover (order crossover OX). For this reason we implement GA with 52 different crossover techniques; each one produce two children; which means 104 different children will be produced and this may discover more search space, also we implement classic GA with order crossover and many experiments were done over 3 Travel Salesman Problem (TSP) to find out which method is better, and according to the results we can say that GA with Multi-crossovers is much better.
Keywords: Artificial intelligence, genetic algorithm, order crossover, travel salesman problem.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1415