Search results for: Juan M. Ortiz-de-Lazcano-Lobato
65 A Message Passing Implementation of a New Parallel Arrangement Algorithm
Authors: Ezequiel Herruzo, Juan José Cruz, José Ignacio Benavides, Oscar Plata
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This paper describes a new algorithm of arrangement in parallel, based on Odd-Even Mergesort, called division and concurrent mixes. The main idea of the algorithm is to achieve that each processor uses a sequential algorithm for ordering a part of the vector, and after that, for making the processors work in pairs in order to mix two of these sections ordered in a greater one, also ordered; after several iterations, the vector will be completely ordered. The paper describes the implementation of the new algorithm on a Message Passing environment (such as MPI). Besides, it compares the obtained experimental results with the quicksort sequential algorithm and with the parallel implementations (also on MPI) of the algorithms quicksort and bitonic sort. The comparison has been realized in an 8 processors cluster under GNU/Linux which is running on a unique PC processor.Keywords: Parallel algorithm, arrangement, MPI, sorting, parallel program.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 169264 Radar Task Schedulers based on Multiple Queue
Authors: María I. Jiménez, Alberto Izquierdo, Juan J. Villacorta, Lara del Val, Mariano Raboso
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There are very complex communication systems, as the multifunction radar, MFAR (Multi-Function Array Radar), where functions are integrated all together, and simultaneously are performed the classic functions of tracking and surveillance, as all the functions related to the communication, countermeasures, and calibration. All these functions are divided into the tasks to execute. The task scheduler is a key element of the radar, since it does the planning and distribution of energy and time resources to be shared and used by all tasks. This paper presents schedulers based on the use of multiple queue. Several schedulers have been designed and studied, and it has been made a comparative analysis of different performed schedulers. The tests and experiments have been done by means of system software simulation. Finally a suitable set of radar characteristics has been selected to evaluate the behavior of the task scheduler working.Keywords: Queue Theory, Radar, Scheduler, Task.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 219963 Removal of Phenylurea Herbicides from Waters by using Chemical Oxidation Treatments
Authors: F. Javier Benitez, Carolina Garcia, Juan Luis Acero, Francisco J. Real
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Four phenylurea herbicides (isoproturon, chlortoluron, diuron and linuron) were dissolved in different water matrices in order to study their chemical degradation by using UV radiation, ozone and some advanced oxidation processes (UV/H2O2, O3/H2O2, Fenton reagent and the photo- Fenton system). The waters used were: ultra-pure water, a commercial mineral water, a groundwater and a surface water taken from a reservoir. Elimination levels were established for each herbicide and for several global quality parameters, and a kinetic study was performed in order to determine basic kinetic parameters of each reaction between the target phenylureas and these oxidizing systems.
Keywords: Phenylurea herbicides, UV radiation; Ozone, Fenton reagent, Hydroxyl radicals, Rate constants, Quantum yields
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 193362 Design, Development and Evaluation of a Portable Recording System to Capture Dynamic Presentations Using the Teacher´s Tablet PC
Authors: Enrique Barra, Abel Carril, Aldo Gordillo, Joaquín Salvachúa, Juan Quemada
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Computers and multimedia equipment have improved a lot in the last years. They have reduced their cost and size while at the same time increased their capabilities. These improvements allowed us to design and implement a portable recording system that also integrates the teacher´s tablet PC to capture what he/she writes on the slides and all that happens in it. This paper explains this system in detail and the validation of the recordings that we did after using it to record all the lectures the “Communications Software” course in our university. The results show that pupils used the recordings for different purposes and consider them useful for a variety of things, especially after missing a lecture.
Keywords: Recording System, capture dynamic presentations, lecture recording.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 192661 Stability Analysis of a Low Power Wind Turbine for the Simultaneous Generation of Energy through Two Electric Generators
Authors: Daniel Icaza, Federico Córdova, Chiristian Castro, Fernando Icaza, Juan Portoviejo
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In this article, the mathematical model is presented, and simulations were carried out using specialized software such as MATLAB before the construction of a 900-W wind turbine. The present study was conducted with the intention of taking advantage of the rotation of the blades of the wind generator after going through a process of amplification of speed by means of a system of gears to finally mechanically couple two electric generators of similar characteristics. This coupling allows generating a maximum voltage of 6 V in DC for each generator and putting in series the 12 V DC is achieved, which is later stored in batteries and used when the user requires it. Laboratory tests were made to verify the level of power generation produced based on the wind speed at the entrance of the blades.
Keywords: Smart grids, wind turbine, modeling, renewable energy, robust control.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 87560 Hopfield Network as Associative Memory with Multiple Reference Points
Authors: Domingo López-Rodríguez, Enrique Mérida-Casermeiro, Juan M. Ortiz-de-Lazcano-Lobato
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Hopfield model of associative memory is studied in this work. In particular, two main problems that it possesses: the apparition of spurious patterns in the learning phase, implying the well-known effect of storing the opposite pattern, and the problem of its reduced capacity, meaning that it is not possible to store a great amount of patterns without increasing the error probability in the retrieving phase. In this paper, a method to avoid spurious patterns is presented and studied, and an explanation of the previously mentioned effect is given. Another technique to increase the capacity of a network is proposed here, based on the idea of using several reference points when storing patterns. It is studied in depth, and an explicit formula for the capacity of the network with this technique is provided.
Keywords: Associative memory, Hopfield network, network capacity, spurious patterns.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 110859 Data Acquisition System for Automotive Testing According to the European Directive 2004/104/EC
Authors: Herminio Martínez-García, Juan Gámiz, Yolanda Bolea, Antoni Grau
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This article presents an interactive system for data acquisition in vehicle testing according to the test process defined in automotive directive 2004/104/EC. The project has been designed and developed by authors for the Spanish company Applus-LGAI. The developed project will result in a new process, which will involve the creation of braking cycle test defined in the aforementioned automotive directive. It will also allow the analysis of new vehicle features that was not feasible, allowing an increasing interaction with the vehicle. Potential users of this system in the short term will be vehicle manufacturers and in a medium term the system can be extended to testing other automotive components and EMC tests.
Keywords: Automotive process, data acquisition system, electromagnetic compatibility (EMC) testing, European Directive 2004/104/EC.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 146458 Production of Bioethanol through Hydrolysis of Agro-Industrial Banana Crop Residues
Authors: Sánchez Acuña, Juan Camilo, Granados Gómez, Mildred Magaly, Navarrete Rodríguez, Luisa Fernanda
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Nowadays, the main biofuels source production as bioethanol is food crops. This means a high competition between foods and energy production. For this reason, it is necessary to take into account the use of new raw materials friendly to the environment. The main objective of this paper is to evaluate the potential of the agro-industrial banana crop residues in the production of bioethanol. A factorial design of 24 was used, the design has variables such as pH, time and concentration of hydrolysis, another variable is the time of fermentation that is of 7 or 15 days. In the hydrolysis phase, the pH is acidic (H2SO4) or basic (NaOH), the time is 30 or 15 minutes and the concentration is 0.1 or 0.5 M. It was observed that basic media, low concentrations, fermentation, and higher pretreatment times produced better performance in terms of biofuel obtained.
Keywords: Bioethanol, biofuels, banana waste, hydrolysis.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 99857 Kinetic Study of Thermal Degradation of a Lignin Nanoparticle-Reinforced Phenolic Foam
Authors: Juan C. Domínguez, Belén Del Saz-Orozco, María V. Alonso, Mercedes Oliet, Francisco Rodríguez
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In the present study, the kinetics of thermal degradation of a phenolic and lignin reinforced phenolic foams, and the lignin used as reinforcement were studied and the activation energies of their degradation processes were obtained by a DAEM model. The average values for five heating rates of the mean activation energies obtained were: 99.1, 128.2, and 144.0 kJ.mol-1 for the phenolic foam; 109.5, 113.3, and 153.0 kJ.mol-1 for the lignin reinforcement; and 82.1, 106.9, and 124.4 kJ.mol-1 for the lignin reinforced phenolic foam. The standard deviation ranges calculated for each sample were 1.27-8.85, 2.22-12.82, and 3.17-8.11 kJ.mol-1 for the phenolic foam, lignin and the reinforced foam, respectively. The DAEM model showed low mean square errors (<1x10-5), proving that is a suitable model to study the kinetics of thermal degradation of the foams and the reinforcement.Keywords: Kinetics, lignin, phenolic foam, thermal degradation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 192256 VDGMSISS: A Verifiable and Detectable Multi-Secret Images Sharing Scheme with General Access Structure
Authors: Justie Su-Tzu Juan, Ming-Jheng Li, Ching-Fen Lee, Ruei-Yu Wu
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A secret image sharing scheme is a way to protect images. The main idea is dispersing the secret image into numerous shadow images. A secret image sharing scheme can withstand the impersonal attack and achieve the highly practical property of multiuse is more practical. Therefore, this paper proposes a verifiable and detectable secret image-sharing scheme called VDGMSISS to solve the impersonal attack and to achieve some properties such as encrypting multi-secret images at one time and multi-use. Moreover, our scheme can also be used for any genera access structure.Keywords: Multi-secret images sharing scheme, verifiable, detectable, general access structure.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 45255 Perturbations of the EM-field Meters Reading Caused by Flat Roof Security Wall
Authors: Alfonso Bahillo, Juan Blas, Santiago Mazuelas, Patricia Fernanadez, Ruben Mateo Lorenzo, Evaristo Jose Abril
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The wide increase and diffusion on telecommunication technologies have caused a huge spread of electromagnetic sources in most European Countries. Since the public is continuously being exposed to electromagnetic radiation the possible health effects have become the focus of population concerns. As a result, electromagnetic field monitoring stations which control field strength in commercial frequency bands are being placed on the flat roof of many buildings. However there is no guidance on where to place them. This paper presents an analysis of frequency, polarization and angles of incidence of a plane wave which impinges on a flat roof security wall and its dependence on electromagnetic field strength meters placement.Keywords: EM field exposition, EM field strength meter, FDTD method, flat roof security wall, plane wave propagation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 131554 Renewable Energy System Eolic-Photovoltaic for the Touristic Center La Tranca-Chordeleg in Ecuador
Authors: Christian Castro Samaniego, Daniel Icaza Alvarez, Juan Portoviejo Brito
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For this research work, hybrid wind-photovoltaic (SHEF) systems were considered as renewable energy sources that take advantage of wind energy and solar radiation to transform into electrical energy. In the present research work, the feasibility of a wind-photovoltaic hybrid generation system was analyzed for the La Tranca tourist viewpoint of the Chordeleg canton in Ecuador. The research process consisted of the collection of data on solar radiation, temperature, wind speed among others by means of a meteorological station. Simulations were carried out in MATLAB/Simulink based on a mathematical model. In the end, we compared the theoretical radiation-power curves and the measurements made at the site.Keywords: Hybrid system, wind turbine, modeling, simulation, validation, experimental data, panel, Ecuador.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 74453 Viscosity of Vegetable Oils and Biodiesel and Energy Generation
Authors: Thiago de O. Macedo, Roberto G. Pereira, Juan M. Pardal, Alexandre S. Soares, Valdir deJ. Lameira
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The present work describes an experimental investigation concerning the determination of viscosity behavior with shear rate and temperature of edible oils: canola; sunflower; corn; soybean and the no edible oil: Jatropha curcas. Besides these, it was tested a blend of canola, corn and sunflower oils as well as sunflower and soybean biodiesel. Based on experiments, it was obtained shear stress and viscosity at different shear rates of each sample at 40ºC, as well as viscosity of each sample at various temperatures in the range of 24 to 85ºC. Furthermore, it was compared the curves obtained for the viscosity versus temperature with the curves obtained by modeling the viscosity dependency on temperature using the Vogel equation. Also a test in a stationary engine was performed in order to study the energy generation using blends of soybean oil and soybean biodiesel with diesel.Keywords: Biofuel, energy generation, vegetable oil, viscosity.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 960652 A New Method to Estimate the Low Income Proportion: Monte Carlo Simulations
Authors: Encarnación Álvarez, Rosa M. García-Fernández, Juan F. Muñoz
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Estimation of a proportion has many applications in economics and social studies. A common application is the estimation of the low income proportion, which gives the proportion of people classified as poor into a population. In this paper, we present this poverty indicator and propose to use the logistic regression estimator for the problem of estimating the low income proportion. Various sampling designs are presented. Assuming a real data set obtained from the European Survey on Income and Living Conditions, Monte Carlo simulation studies are carried out to analyze the empirical performance of the logistic regression estimator under the various sampling designs considered in this paper. Results derived from Monte Carlo simulation studies indicate that the logistic regression estimator can be more accurate than the customary estimator under the various sampling designs considered in this paper. The stratified sampling design can also provide more accurate results.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 194051 A Video-based Algorithm for Moving Objects Detection at Signalized Intersection
Authors: Juan Li, Chunfu Shao, Chunjiao Dong, Dan Zhao, Yinhong Liu
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Mixed-traffic (e.g., pedestrians, bicycles, and vehicles) data at an intersection is one of the essential factors for intersection design and traffic control. However, some data such as pedestrian volume cannot be directly collected by common detectors (e.g. inductive loop, sonar and microwave sensors). In this paper, a video based detection algorithm is proposed for mixed-traffic data collection at intersections using surveillance cameras. The algorithm is derived from Gaussian Mixture Model (GMM), and uses a mergence time adjustment scheme to improve the traditional algorithm. Real-world video data were selected to test the algorithm. The results show that the proposed algorithm has the faster processing speed and more accuracy than the traditional algorithm. This indicates that the improved algorithm can be applied to detect mixed-traffic at signalized intersection, even when conflicts occur.Keywords: detection, intersection, mixed traffic, moving objects.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 203350 Greenhouse Gas Emissions from a Tropical Eutrophic Freshwater Wetland
Authors: Juan P. Silva, T. R. Canchala, H. J. Lubberding, E. J. Peña, H. J. Gijzen
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This study measured the fluxes of greenhouse gases (GHGs) i.e. CO2, CH4 and N2O from a tropical eutrophic freshwater wetland (“Sonso Lagoon”) which receives input loading nutrient from several sources i.e. agricultural run-off, domestic sewage, and a polluted river. The flux measurements were carried out at four different points using the static chamber technique. CO2 fluxes ranged from -8270 to 12210 mg.m-2.d-1 (median = 360; SD = 4.11; n = 50), CH4 ranged between 0.2 and 5270 mg.m-2.d-1 (median = 60; SD = 1.27; n = 45), and N2O ranged from -31.12 to 15.4 mg N2O m-2.d-1 (median = 0.05; SD = 9.36; n = 42). Although some negative fluxes were observed in the zone dominated by floating plants i.e. Eichornia crassipes, Salvinia sp., and Pistia stratiotes L., the mean values indicated that the Sonso Lagoon was a net source of CO2, CH4 and N2O. In addition, an effect of the eutrophication on GHG emissions could be observed in the positive correlation found between CO2, CH4 and N2O generation and COD, PO4-3, NH3-N, TN and NO3-N. The eutrophication impact on GHG production highlights the necessity to limit the anthropic activities on freshwater wetlands.
Keywords: Eutrophication, greenhouse gas emissions, freshwater wetlands, climate change.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 210749 Current Status of 5A Lab6 Hollow Cathode Life Tests in Lanzhou Institute of Physics, China
Authors: Yanhui Jia, Ning Guo, Juan Li, Yunkui Sun, Wei Yang, Tianping Zhang, Lin Ma, Wei Meng, Hai Geng
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The current statuses of lifetime test of LaB6 hollow cathode at the Lanzhou Institute of Physics (LIP), China, was described. 5A LaB6 hollow cathode was design for LIPS-200 40mN Xenon ion thruster, and it could be used for LHT-100 80 mN Hall thruster, too. Life test of the discharge and neutralizer modes of LHC-5 hollow cathode were stared in October 2011, and cumulative operation time reached 17,300 and 16,100 hours in April 2015, respectively. The life of cathode was designed more than 11,000 hours. Parameters of discharge and key structure dimensions were monitored in different stage of life test indicated that cathodes were health enough. The test will continue until the cathode cannot work or operation parameter is not in normally. The result of the endurance test of cathode demonstrated that the LaB6 hollow cathode is satisfied for the required of thruster in life and performance.Keywords: LaB6, hollow cathode, thruster, lifetime test, electric propulsion.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 219448 Ion Thruster Grid Lifetime Assessment Based on Its Structural Failure
Authors: Juan Li, Jiawen Qiu, Yuchuan Chu, Tianping Zhang, Wei Meng, Yanhui Jia, Xiaohui Liu
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This article developed an ion thruster optic system sputter erosion depth numerical 3D model by IFE-PIC (Immersed Finite Element-Particle-in-Cell) and Mont Carlo method, and calculated the downstream surface sputter erosion rate of accelerator grid; compared with LIPS-200 life test data. The results of the numerical model are in reasonable agreement with the measured data. Finally, we predicted the lifetime of the 20cm diameter ion thruster via the erosion data obtained with the model. The ultimate result demonstrated that under normal operating condition, the erosion rate of the grooves wears on the downstream surface of the accelerator grid is 34.6μm⁄1000h, which means the conservative lifetime until structural failure occurring on the accelerator grid is 11500 hours.Keywords: Ion thruster, accelerator gird, sputter erosion, lifetime assessment.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 200147 Modeling and Simulation of Flow Shop Scheduling Problem through Petri Net Tools
Authors: Joselito Medina Marin, Norberto Hernández Romero, Juan Carlos Seck Tuoh Mora, Erick S. Martinez Gomez
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The Flow Shop Scheduling Problem (FSSP) is a typical problem that is faced by production planning managers in Flexible Manufacturing Systems (FMS). This problem consists in finding the optimal scheduling to carry out a set of jobs, which are processed in a set of machines or shared resources. Moreover, all the jobs are processed in the same machine sequence. As in all the scheduling problems, the makespan can be obtained by drawing the Gantt chart according to the operations order, among other alternatives. On this way, an FMS presenting the FSSP can be modeled by Petri nets (PNs), which are a powerful tool that has been used to model and analyze discrete event systems. Then, the makespan can be obtained by simulating the PN through the token game animation and incidence matrix. In this work, we present an adaptive PN to obtain the makespan of FSSP by applying PN analytical tools.
Keywords: Flow-shop scheduling problem, makespan, Petri nets, state equation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 173946 An Open Loop Distribution Module for Precise and Uniform Drip Fertigation in Soilless Culture
Authors: Juan Ignacio Arango, Andres Diaz, Giacomo Barbieri
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In soilless culture, the definition of efficient fertigation strategies is fundamental for the growth of crops. Flexible test-benches able to independently manage groups of crops are key for investigating efficient fertigation practices through experimentation. These test-benches must be able to provide nutrient solution (NS) in a precise, uniform and repeatable way in order to effectively implement and compare different fertigation strategies. This article describes a distribution module for investigating fertigation practices able to control the fertigation dose and frequency. The proposed solution is characterized in terms of precision, uniformity and repeatability since these parameters are fundamental in the implementation of effective experiments for the investigation of fertigation practices. After a calibration process, the implemented system reaches a precision of 1mL, a uniformity of 98.5% at a total cost of 735USD.Keywords: Precision horticulture, test-bench, fertigation strategy, automation, flexibility.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 101245 Application of Sensory Thermography on Workers of a Wireless Industry in Mexico
Authors: Claudia Camargo, Enrique J. de la Vega, Jesús E. Olguín, Juan A. López, Sandra K. Enríquez
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This study focuses on the application of sensory thermography, as a non-invasive method to evaluate the musculoskeletal injuries that industry workers performing Highly Repetitive Movements (HRM) may acquire. It was made at a wireless company having the target of analyze temperatures in worker’s wrists, elbows and shoulders in workstations during their activities, this thru sensorial thermography with the goal of detecting maximum temperatures (Tmax) that could indicate possible injuries. The tests were applied during 3 hours for only 2 workers that work in workstations where there’s been the highest index of injuries and accidents. We were made comparisons for each part of the body that were study for both because of the similitude between the activities of the workstations; they were requiring both an immediate evaluation. The Tmax was recorder during the test of the worker 2, in the left wrist, reaching a temperature of 35.088ºC and with a maximum increase of 1.856°C
Keywords: Highly Repetitive Movements (HRM), Maximum temperatures (Tmax), Worker.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 156944 Microbiological Analysis, Cytotoxic and Genotoxic Effects from Material Captured in PM2.5 and PM10 Filters Used in the Aburrá Valley Air Quality Monitoring Network (Colombia)
Authors: Carmen E. Zapata, Juan Bautista, Olga Montoya, Claudia Moreno, Marisol Suarez, Alejandra Betancur, Duvan Nanclares, Natalia A. Cano
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This study aims to evaluate the diversity of microorganisms in filters PM2.5 and PM10; and determine the genotoxic and cytotoxic activity of the complex mixture present in PM2.5 filters used in the Aburrá Valley Air Quality Monitoring Network (Colombia). The research results indicate that particulate matter PM2.5 of different monitoring stations are bacteria; however, this study of detection of bacteria and their phylogenetic relationship is not complete evidence to connect the microorganisms with pathogenic or degrading activities of compounds present in the air. Additionally, it was demonstrated the damage induced by the particulate material in the cell membrane, lysosomal and endosomal membrane and in the mitochondrial metabolism; this damage was independent of the PM2.5 concentrations in almost all the cases.Keywords: Cytotoxic, genotoxic, microbiological analysis, PM10, PM2.5.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 233443 Real-Time Testing of Steel Strip Welds based on Bayesian Decision Theory
Authors: Julio Molleda, Daniel F. García, Juan C. Granda, Francisco J. Suárez
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One of the main trouble in a steel strip manufacturing line is the breakage of whatever weld carried out between steel coils, that are used to produce the continuous strip to be processed. A weld breakage results in a several hours stop of the manufacturing line. In this process the damages caused by the breakage must be repaired. After the reparation and in order to go on with the production it will be necessary a restarting process of the line. For minimizing this problem, a human operator must inspect visually and manually each weld in order to avoid its breakage during the manufacturing process. The work presented in this paper is based on the Bayesian decision theory and it presents an approach to detect, on real-time, steel strip defective welds. This approach is based on quantifying the tradeoffs between various classification decisions using probability and the costs that accompany such decisions.Keywords: Classification, Pattern Recognition, ProbabilisticReasoning, Statistical Data Analysis.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 141042 Apoptosis Induced by Low-concentration Ethanol in Hepatocellular Carcinoma Cell Strains and Down-regulated AFP and Survivin Analysis by Proteomic Technology
Authors: Xin Kai, Juan Li, Sexin Huang, Zengliang Bai
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Ethanol is generally used as a therapeutic reagent against Hepatocellular carcinoma (HCC or hepatoma) worldwide, as it can induce Hepatocellular carcinoma cell apoptosis at low concentration through a multifactorial process regulated by several unknown proteins. This paper provides a simple and available proteomic strategy for exploring differentially expressed proteins in the apoptotic pathway. The appropriate concentrations of ethanol required to induce HepG2 cell apoptosis were first assessed by MTT assay, Gisma and fluorescence staining. Next, the central proteins involved in the apoptosis pathway processs were determined using 2D-PAGE, SDS-PAGE, and bio-software analysis. Finally the downregulation of two proteins, AFP and survivin, were determined by immunocytochemistry and reverse transcriptase PCR (RT-PCR) technology. The simple, useful method demonstrated here provides a new approach to proteomic analysis in key bio-regulating process including proliferation, differentiation, apoptosis, immunity and metastasis.
Keywords: Hepatocellular carcinoma, Ethanol, Proteomics, survivin and AFP
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 196241 Removal of Pharmaceutical Compounds by a Sequential Treatment of Ozonation Followed by Fenton Process: Influence of the Water Matrix
Authors: Almudena Aguinaco, Olga Gimeno, Fernando J. Beltrán, Juan José P. Sagasti
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A sequential treatment of ozonation followed by a Fenton or photo-Fenton process, using black light lamps (365 nm) in this latter case, has been applied to remove a mixture of pharmaceutical compounds and the generated by-products both in ultrapure and secondary treated wastewater. The scientifictechnological innovation of this study stems from the in situ generation of hydrogen peroxide from the direct ozonation of pharmaceuticals, and can later be used in the application of Fenton and photo-Fenton processes. The compounds selected as models were sulfamethoxazol and acetaminophen. It should be remarked that the use of a second process is necessary as a result of the low mineralization yield reached by the exclusive application of ozone. Therefore, the influence of the water matrix has been studied in terms of hydrogen peroxide concentration, individual compound concentration and total organic carbon removed. Moreover, the concentration of different iron species in solution has been measured.Keywords: Fenton, photo-Fenton, ozone, pharmaceutical compounds, hydrogen peroxide, water treatment
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 184440 On Speeding Up Support Vector Machines: Proximity Graphs Versus Random Sampling for Pre-Selection Condensation
Authors: Xiaohua Liu, Juan F. Beltran, Nishant Mohanchandra, Godfried T. Toussaint
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Support vector machines (SVMs) are considered to be the best machine learning algorithms for minimizing the predictive probability of misclassification. However, their drawback is that for large data sets the computation of the optimal decision boundary is a time consuming function of the size of the training set. Hence several methods have been proposed to speed up the SVM algorithm. Here three methods used to speed up the computation of the SVM classifiers are compared experimentally using a musical genre classification problem. The simplest method pre-selects a random sample of the data before the application of the SVM algorithm. Two additional methods use proximity graphs to pre-select data that are near the decision boundary. One uses k-Nearest Neighbor graphs and the other Relative Neighborhood Graphs to accomplish the task.Keywords: Machine learning, data mining, support vector machines, proximity graphs, relative-neighborhood graphs, k-nearestneighbor graphs, random sampling, training data condensation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 191939 The Cardiac Diagnostic Prediction Applied to a Designed Holter
Authors: Leonardo Juan Ramírez López, Javier Oswaldo Rodriguez Velasquez
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We have designed a Holter that measures the heart´s activity for over 24 hours, implemented a prediction methodology, and generate alarms as well as indicators to patients and treating physicians. Various diagnostic advances have been developed in clinical cardiology thanks to Holter implementation; however, their interpretation has largely been conditioned to clinical analysis and measurements adjusted to diverse population characteristics, thus turning it into a subjective examination. This, however, requires vast population studies to be validated that, in turn, have not achieved the ultimate goal: mortality prediction. Given this context, our Insight Research Group developed a mathematical methodology that assesses cardiac dynamics through entropy and probability, creating a numerical and geometrical attractor which allows quantifying the normalcy of chronic and acute disease as well as the evolution between such states, and our Tigum Research Group developed a holter device with 12 channels and advanced computer software. This has been shown in different contexts with 100% sensitivity and specificity results.
Keywords: Entropy, mathematical, prediction, cardiac, holter, attractor.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 71138 Base Change for Fisher Metrics: Case of the q−Gaussian Inverse Distribution
Authors: Gabriel I. Loaiza O., Carlos A. Cadavid M., Juan C. Arango P.
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It is known that the Riemannian manifold determined by the family of inverse Gaussian distributions endowed with the Fisher metric has negative constant curvature κ = −1/2 , as does the family of usual Gaussian distributions. In the present paper, firstly we arrive at this result by following a different path, much simpler than the previous ones. We first put the family in exponential form, thus endowing the family with a new set of parameters, or coordinates, θ1, θ2; then we determine the matrix of the Fisher metric in terms of these parameters; and finally we compute this matrix in the original parameters. Secondly, we define the Inverse q−Gaussian distribution family (q < 3), as the family obtained by replacing the usual exponential function by the Tsallis q−exponential function in the expression for the Inverse Gaussian distribution, and observe that it supports two possible geometries, the Fisher and the q−Fisher geometry. And finally, we apply our strategy to obtain results about the Fisher and q−Fisher geometry of the Inverse q−Gaussian distribution family, similar to the ones obtained in the case of the Inverse Gaussian distribution family.
Keywords: Base of Changes, Information Geometry, Inverse Gaussian distribution, Inverse q-Gaussian distribution, Statistical Manifolds.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 38637 Artificial Neural Network Development by means of Genetic Programming with Graph Codification
Authors: Daniel Rivero, Julián Dorado, Juan R. Rabuñal, Alejandro Pazos, Javier Pereira
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The development of Artificial Neural Networks (ANNs) is usually a slow process in which the human expert has to test several architectures until he finds the one that achieves best results to solve a certain problem. This work presents a new technique that uses Genetic Programming (GP) for automatically generating ANNs. To do this, the GP algorithm had to be changed in order to work with graph structures, so ANNs can be developed. This technique also allows the obtaining of simplified networks that solve the problem with a small group of neurons. In order to measure the performance of the system and to compare the results with other ANN development methods by means of Evolutionary Computation (EC) techniques, several tests were performed with problems based on some of the most used test databases. The results of those comparisons show that the system achieves good results comparable with the already existing techniques and, in most of the cases, they worked better than those techniques.Keywords: Artificial Neural Networks, Evolutionary Computation, Genetic Programming.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 146036 Experimental Characterization of the Color Quality and Error Rate for an Red, Green, and Blue-Based Light Emission Diode-Fixture Used in Visible Light Communications
Authors: Juan F. Gutierrez, Jesus M. Quintero, Diego Sandoval
Abstract:
An important feature of Lighting Emitting Diodes (LED) technology is the fast on-off commutation. This fact allows data transmission using modulation formats such as On-Off Keying (OOK) and Color Shift Keying (CSK). Since, CSK based on three color bands uses red, green, and blue monochromatic LED (RGB-LED) to define a pattern of chromaticities; this type of CSK provides poor color quality on the illuminated area. In this work, we present the design and implementation of a VLC system using RGB-based CSK with 16, 8, and 4 color points, mixing with a steady baseline of a phosphor white-LED, to improve the color quality of the LED-Fixture. The experimental system was assessed in terms of the Symbol Error Rate (SER) and the Color Rendering Index (CRI). Good color quality performance of the LED-Fixture was obtained with an acceptable SER. We describe the laboratory setup used to characterize and calibrate an LED-Fixture.
Keywords: Color rendering index, symbol error rate, color shift keying, visible light communications.
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