Search results for: degradation signal
1811 Comparison Analysis of Multi-Channel Echo Cancellation Using Adaptive Filters
Authors: Sahar Mobeen, Anam Rafique, Irum Baig
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Acoustic echo cancellation in multichannel is a system identification application. In real time environment, signal changes very rapidly which required adaptive algorithms such as Least Mean Square (LMS), Leaky Least Mean Square (LLMS), Normalized Least Mean square (NLMS) and average (AFA) having high convergence rate and stable. LMS and NLMS are widely used adaptive algorithm due to less computational complexity and AFA used of its high convergence rate. This research is based on comparison of acoustic echo (generated in a room) cancellation thorough LMS, LLMS, NLMS, AFA and newly proposed average normalized leaky least mean square (ANLLMS) adaptive filters.Keywords: LMS, LLMS, NLMS, AFA, ANLLMS
Procedia PDF Downloads 5661810 Durability of Reinforced Concrete Structure on Very High Aggressive Environment: A Case Study
Authors: Karla Peitl Miller, Leomar Bravin Porto, Kaitto Correa Fraga, Nataniele Eler Mendes
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This paper presents the evaluation and study of a real reinforced concrete structure of a fertilizer storage building, constructed on a Vale’s Port at Brazil, which has been recently under refurbishment. Data that will be shared and commented aim to show how wrong choices in project concepts allied to a very high aggressive environment lead to a fast track degradation, incurring on a hazardous condition associated with huge and expensive treatment for repair and guarantee of minimum performance conditions and service life. It will be also shown and discussed all the covered steps since pathological manifestations first signs were observed until the complete revitalization and reparation planning would be drawn. The conclusions of the work easily explicit the importance of professional technical qualification, the importance of minimum requirements for design and structural reforms, and mainly, the importance of good inspection and diagnostic engineering continuous work.Keywords: durability, reinforced concrete repair, structural inspection, diagnostic engineering
Procedia PDF Downloads 1371809 Study of Mechanical Behavior of Unidirectional Composite Laminates According
Authors: Deliou Adel, Saadalah Younes, Belkaid Khmissi, Dehbi Meriem
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Composite materials, in the most common sense of the term, are a set of synthetic materials designed and used mainly for structural applications; the mechanical function is dominant. The mechanical behaviors of the composite, as well as the degradation mechanisms leading to its rupture, depend on the nature of the constituents and on the architecture of the fiber preform. The profile is required because it guides the engineer in designing structures with precise properties in relation to the needs. This work is about studying the mechanical behavior of unidirectional composite laminates according to different failure criteria. Varying strength parameter values make it possible to compare the ultimate mechanical characteristics obtained by the criteria of Tsai-Hill, Fisher and maximum stress. The laminate is subjected to uniaxial tensile membrane forces. Estimates of their ultimate strengths and the plotting of the failure envelope constitute the principal axis of this study. Using the theory of maximum stress, we can determine the various modes of damage of the composite. The different components of the deformation are presented for different orientations of fibers.Keywords: unidirectional kevlar/epoxy composite, failure criterion, membrane stress, deformations, failure envelope
Procedia PDF Downloads 881808 Lifting Wavelet Transform and Singular Values Decomposition for Secure Image Watermarking
Authors: Siraa Ben Ftima, Mourad Talbi, Tahar Ezzedine
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In this paper, we present a technique of secure watermarking of grayscale and color images. This technique consists in applying the Singular Value Decomposition (SVD) in LWT (Lifting Wavelet Transform) domain in order to insert the watermark image (grayscale) in the host image (grayscale or color image). It also uses signature in the embedding and extraction steps. The technique is applied on a number of grayscale and color images. The performance of this technique is proved by the PSNR (Pick Signal to Noise Ratio), the MSE (Mean Square Error) and the SSIM (structural similarity) computations.Keywords: lifting wavelet transform (LWT), sub-space vectorial decomposition, secure, image watermarking, watermark
Procedia PDF Downloads 2761807 Metallacyclodimeric Array Containing Both Suprachannels and Cages: Selective Reservoir and Recognition of Diiodomethane
Authors: Daseul Lee, Jeong Jun Lee, Ok-Sang Jung
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Self-assembly of a series of ZnX2 (X- = Cl-, Br-, and I-) with 2,3-bis(4’-nicotinamidephenoxy)naphthalene (L) as a new bidentate pyridyl-donor ligand yields systematic metallacyclodimeric unit, [ZnX2L]2. The supramolecule constitutes a characteristically stacked forming both 1D suprachannels and cages. Weak C-H⋯π and inter-digitated π⋯π interactions are main driving forces in the formation of both suprachannels and cages. The slightly different features between the suprachannel and cage have been investigated by 1H NMR and TG analysis, which solvent quantitatively exchange within only suprachannels. Photo-unstable CH2I2 molecules are stabilized via capturing within suprachannels, which is monitored by UV-Vis spectroscopy. Furthermore, the photoluminescence intensity, from the chromophore naphthyl moiety of [ZnCl2L]2, gradually decreases with the addition of CH2I2. And washing off the CH2I2 by dichloromethane returned the PL intensity back to its approximately original signal.Keywords: metallacyclodimer, suprachannel, π⋯π interaction, molecular recognition
Procedia PDF Downloads 3221806 Radar-Based Classification of Pedestrian and Dog Using High-Resolution Raw Range-Doppler Signatures
Authors: C. Mayr, J. Periya, A. Kariminezhad
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In this paper, we developed a learning framework for the classification of vulnerable road users (VRU) by their range-Doppler signatures. The frequency-modulated continuous-wave (FMCW) radar raw data is first pre-processed to obtain robust object range-Doppler maps per coherent time interval. The complex-valued range-Doppler maps captured from our outdoor measurements are further fed into a convolutional neural network (CNN) to learn the classification. This CNN has gone through a hyperparameter optimization process for improved learning. By learning VRU range-Doppler signatures, the three classes 'pedestrian', 'dog', and 'noise' are classified with an average accuracy of almost 95%. Interestingly, this classification accuracy holds for a combined longitudinal and lateral object trajectories.Keywords: machine learning, radar, signal processing, autonomous driving
Procedia PDF Downloads 2451805 Piezoelectric Micro-generator Characterization for Energy Harvesting Application
Authors: José E. Q. Souza, Marcio Fontana, Antonio C. C. Lima
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This paper presents analysis and characterization of a piezoelectric micro-generator for energy harvesting application. A low-cost experimental prototype was designed to operate as piezoelectric micro-generator in the laboratory. An input acceleration of 9.8m/s2 using a sine signal (peak-to-peak voltage: 1V, offset voltage: 0V) at frequencies ranging from 10Hz to 160Hz generated a maximum average power of 432.4μW (linear mass position = 25mm) and an average power of 543.3μW (angular mass position = 35°). These promising results show that the prototype can be considered for low consumption load application as an energy harvesting micro-generator.Keywords: piezoelectric, micro-generator, energy harvesting, cantilever beam
Procedia PDF Downloads 4651804 Radiation Stability of Pigment ZnO Modified by Nanopowders
Authors: Chundong Li, V. V. Neshchimenko, M. M. Mikhailov
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The effect of the modification of ZnO powders by ZrO2, Al2O3, TiO2, SiO2, CeO2 and Y2O3 nanoparticles with a concentration of 1-30 wt % is investigated by diffuse reflectance spectra within the wavelength range 200 to 2500 nm before and after 100 keV proton and electron irradiation. It has been established that the introduction of nanoparticles ZrO2, Al2O3 enhances the optical stability of the pigments under proton irradiation, but reduces it under electron irradiation. Modifying with TiO2, SiO2, CeO2, Y2O3 nanopowders leads to decrease radiation stability in both types of irradiation. Samples modified by 5 wt. % of ZrO2 nanoparticles have the highest stability of optical properties after proton exposure. The degradation of optical properties under electron irradiation is not high for this concentration of nanoparticles. A decrease in the absorption of pigments modified with nanoparticles proton exposure is determined by a decrease in the intensity of bands located in the UV and visible regions. After electron exposure the absorption bands have in the whole spectrum range.Keywords: irradiation, nanopowders, radiation stability, zinc oxide
Procedia PDF Downloads 4251803 Drying of Agro-Industrial Wastes Using an Indirect Solar Dryer
Authors: N. Metidji, N. Kasbadji Merzouk, O. Badaoui, R. Sellami, A. Djebli
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The Agro-industry is considered as one of the most waste producing industrial fields as a result of food processing. Upgrading and reuse of these wastes as animal or poultry food seems to be a promising alternative. Combined with the use of clean energy resources, the recovery process would contribute more to the environment protection. It is in this framework that a new solar dryer has been designed in the Unit of Solar Equipments Development. Indirect solar drying has, also, many advantages compared to natural sun drying. In fact, the first does not cause product degradation as it is protected by the drying chamber from direct sun, insects and exterior environment. The aim of this work is to study the drying kinetics of waste, generated during the processing of orange to make fruit juice, by using an indirect forced convection solar dryer at 50 °C and 60 °C, the rate of moisture removal from the product to be dried has been found to be directly related to temperature, humidity and flow rate. The characterization of these parameters has allowed the determination of the appropriate drying time for this product namely orange waste.Keywords: solar energy, solar dryer, energy conversion, orange drying, forced convection solar dryer
Procedia PDF Downloads 3541802 3D Printing of Polycaprolactone Scaffold with Multiscale Porosity Via Incorporation of Sacrificial Sucrose Particles
Authors: Mikaela Kutrolli, Noah S. Pereira, Vanessa Scanlon, Mohamadmahdi Samandari, Ali Tamayol
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Bone tissue engineering has drawn significant attention and various biomaterials have been tested. Polymers such as polycaprolactone (PCL) offer excellent biocompatibility, reasonable mechanical properties, and biodegradability. However, PCL scaffolds suffer a critical drawback: a lack of micro/mesoporosity, affecting cell attachment, tissue integration, and mineralization. It also results in a slow degradation rate. While 3D-printing has addressed the issue of macroporosity through CAD-guided fabrication, PCL scaffolds still exhibit poor smaller-scale porosity. To overcome this, we generated composites of PCL, hydroxyapatite (HA), and powdered sucrose (PS). The latter serves as a sacrificial material to generate porous particles after sucrose dissolution. Additionally, we have incorporated dexamethasone (DEX) to boost the PCL osteogenic properties. The resulting scaffolds maintain controlled macroporosity from the lattice print structure but also develop micro/mesoporosity within PCL fibers when exposed to aqueous environments. The study involved mixing PS into solvent-dissolved PCL in different weight ratios of PS to PCL (70:30, 50:50, and 30:70 wt%). The resulting composite was used for 3D printing of scaffolds at room temperature. Printability was optimized by adjusting pressure, speed, and layer height through filament collapse and fusion test. Enzymatic degradation, porogen leaching, and DEX release profiles were characterized. Physical properties were assessed using wettability, SEM, and micro-CT to quantify the porosity (percentage, pore size, and interconnectivity). Raman spectroscopy was used to verify the absence of sugar after leaching. Mechanical characteristics were evaluated via compression testing before and after porogen leaching. Bone marrow stromal cells (BMSCs) behavior in the printed scaffolds was studied by assessing viability, metabolic activity, osteo-differentiation, and mineralization. The scaffolds with a 70% sugar concentration exhibited superior printability and reached the highest porosity of 80%, but performed poorly during mechanical testing. A 50% PS concentration demonstrated a 70% porosity, with an average pore size of 25 µm, favoring cell attachment. No trace of sucrose was found in Raman after leaching the sugar for 8 hours. Water contact angle results show improved hydrophilicity as the sugar concentration increased, making the scaffolds more conductive to cell adhesion. The behavior of bone marrow stromal cells (BMSCs) showed positive viability and proliferation results with an increasing trend of mineralization and osteo-differentiation as the sucrose concentration increased. The addition of HA and DEX also promoted mineralization and osteo-differentiation in the cultures. The integration of PS as porogen at a concentration of 50%wt within PCL scaffolds presents a promising approach to address the poor cell attachment and tissue integration issues of PCL in bone tissue engineering. The method allows for the fabrication of scaffolds with tunable porosity and mechanical properties, suitable for various applications. The addition of HA and DEX further enhanced the scaffolds. Future studies will apply the scaffolds in an in-vivo model to thoroughly investigate their performance.Keywords: bone, PCL, 3D printing, tissue engineering
Procedia PDF Downloads 581801 Contrast Enhanced Magnetic Resonance Angiography in Rats with Gadobenate Dimeglumine at 3T
Authors: Jao Jo-Chi, Chen Yen-Ku, Jaw Twei-Shiun, Chen Po-Chou
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This study aimed to investigate the magnetic resonance (MR) signal enhancement ratio (ER) of contrast-enhanced MR angiography (CE-MRA) in normal rats with gadobenate dimeglumine (Gd-BOPTA) using a clinical 3T scanner and an extremity coil. The relaxivities of Gd-BOPTA with saline only and with 4.5 % human serum albumin (HSA) were also measured. Compared with Gadolinium diethylenetriamine pentaacetic acid (Gd-DTPA), Gd-BOPTA had higher relaxivities. The maximum ER of Aorta (ERa), kidney, liver and muscle with Gd-BOPTA were higher than those with Gd-DTPA. The maximum ERa appeared at 1.2 min and decayed to half at 10 min after Gd-BOPTA injection. This information is helpful for the design of CE-MRA study of rats.Keywords: contrast-enhanced magnetic resonance angiography, Gd-BOPTA, Gd-DTPA, rat
Procedia PDF Downloads 6281800 Cooperative AF Scheme for Multi Source and Terminal in Edge of Cell Coverage
Authors: Myoung-Jin Kim, Chang-Bin Ha, Yeong-Seop Ahn, Hyoung-Kyu Song
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This paper proposes a cooperative communication scheme for improve wireless communication performance. When the receiver is located in the edge of coverage, the signal from the transmitter is distorted for various reasons such as inter-cell interference (ICI), power reduction, incorrect channel estimation. In order to improve communication performance, the proposed scheme adds the relay. By the relay, the receiver has diversity gain. In this paper, two base stations, one relay and one destination are considered. The two base stations transmit same time to relay and destination. The relay forwarding to destination and the destination detects signals.Keywords: cooperative communication, diversity gain, OFDM, MMSE
Procedia PDF Downloads 3891799 Production of Ethanol from Mission Grass
Authors: Darin Khumsupan, Tidarat Komolwanich, Sirirat Prasertwasu, Thanyalak Chaisuwan, Apanee Luengnaruemitchai, Sujitra Wongkasemjit
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Bioethanol production has become a subject of interest for many researchers due to its potential to replace fossil fuels. Since the most popular sources of bioethanol originate from food crops including corn and sugarcane, many people become more concerned with increasing demand for food supply. Lignocellulosic biomass, such as grass, could be a practical alternative to replace the conventional fossil fuels due to its low cost, renewability, and abundance in nature. Mission grass (Pennisetum polystachion) is one of the candidates for bioethanol production. This research is focused on the detoxification and fermentation of hydrolysate from mission grass. Glucose in the hydrolysate was detoxified by overliming process at various pH. Although overliming at pH 12 gave the highest yeast population, the ethanol yield was low due to glucose degradation. Overliming at pH 10 showed the highest yield of ethanol production. Various strains of Baker’s yeast (Saccharomyces cerevisiae) will be utilized to produce ethanol at the optimal overliming pH.Keywords: Pennisetum polystachion, lignocellulosic biomass, bioethanol production, detoxification, overliming, Saccharomyces cerevisiae
Procedia PDF Downloads 3841798 Seismic Behaviour of CFST-RC Columns
Authors: Raghabendra Yadav, Baochun Chen, Huihui Yuan, Zhibin Lian
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Concrete Filled Steel Tube (CFST) columns are widely used in Civil Engineering Structures due to their abundant properties. CFST-RC column is a built up column in which CFST members are connected with RC web. The CFST-RC column has excellent static and earthquake resistant properties, such as high strength, high ductility and large energy absorption capacity. CFST-RC columns have been adopted as piers in Ganhaizi Bridge in high seismic risk zone with a highest pier of 107m. The experimental investigation on scaled models of similar type of the CFST-RC pier are carried out. The experimental investigation on scaled models of similar type of the CFST-RC pier are carried out. Under cyclic loading, the hysteretic performance of CFST-RC columns, such as failure modes, ductility, load displacement hysteretic curves, energy absorption capacity, strength and stiffness degradation are studied in this paper.Keywords: CFST, cyclic load, Ganhaizi bridge, seismic performance
Procedia PDF Downloads 2461797 Heterogeneous Photocatalytic Degradation of Methylene Blue by Montmorillonite/CuxCd1-xs Nanomaterials
Authors: Horiya Boukhatem, Lila Djouadi, Hussein Khalaf, Rufino Manuel Navarro Yerga, Fernando Vaquero Gonzalez
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Heterogeneous photo catalysis is an alternative method for the removal of organic pollutants in water. The photo excitation of a semi-conductor under ultra violet (UV) irradiation entails the production of hydroxyl radicals, one of the most oxidative chemical species. The objective of this study is the synthesis of nano materials based on montmorillonite and CuxCd1-xS with different Cu concentration (0.3 < x < 0.7) and their application in photocatalysis of a cationic dye: methylene blue. The synthesized nano materials and montmorillonite were characterized by fourier transform infrared (FTIR). Test results of photo catalysis of methylene blue under UV-Visible irradiation show that the photoactivity of nano materials montmorillonite/ CuxCd1-xS increase with the increasing of Cu concentration and it is significantly higher compared to that of sodium montmorillonite alone. The application of the kinetic model of Langmuir-Hinshelwood (L-H) to the photocatalytic test results showed that the reaction rate obeys to the first-order kinetic model.Keywords: heterogeneous photo catalysis, methylene blue, montmorillonite, nano material
Procedia PDF Downloads 3391796 Experimental Study of the Infill Masonry Walls Response Subjected to Out-Of-Plane Static Loadings
Authors: André Furtado, Hugo Rodrigues, António Arêde, Humberto Varum
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Besides characterized as non-structural elements, infill masonry (IM) walls have an important contribute in the structural response of reinforced concrete structures as proved by the damages observed recent earthquakes. In particular, the out-of-plane (OOP) collapse has been one of the most observed failure mechanism. The aim of this research is to contribute to the increase of understanding regarding the OOP behaviour of full-scale infill panels considering different variables such as panel support width and axial load on the top of columns. For this, it was carried out in the Laboratory of Earthquake and Structural Engineering (LESE) an experimental campaign of five full-scale IM walls subjected to OOP distributed cyclic loadings. Specimens with different variables such as previous in-plane damage, support conditions, axial load on the top of the columns were studied. The results will be presented and discussed along the manuscript in terms of force-displacement hysteretic curves, cracking pattern, initial stiffness, stiffness degradation and accumulative energy dissipation.Keywords: infill masonry walls, experimental testing, out-of-plane, full-scale
Procedia PDF Downloads 3901795 Speckle Noise Reduction Using Anisotropic Filter Based on Wavelets
Authors: Kritika Bansal, Akwinder Kaur, Shruti Gujral
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In this paper, the approach of denoising is solved by using a new hybrid technique which associates the different denoising methods. Wavelet thresholding and anisotropic diffusion filter are the two different filters in our hybrid techniques. The Wavelet thresholding removes the noise by removing the high frequency components with lesser edge preservation, whereas an anisotropic diffusion filters is based on partial differential equation, (PDE) to remove the speckle noise. This PDE approach is used to preserve the edges and provides better smoothing. So our new method proposes a combination of these two filtering methods which performs better results in terms of peak signal to noise ratio (PSNR), coefficient of correlation (COC) and equivalent no of looks (ENL).Keywords: denoising, anisotropic diffusion filter, multiplicative noise, speckle, wavelets
Procedia PDF Downloads 5121794 A Multi Function Myocontroller for Upper Limb Prostheses
Authors: Ayad Asaad Ibrahim
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Myoelectrically controlled prostheses are becoming more and more popular, for below-elbow amputation, the wrist flexor and extensor muscle group, while for above-elbow biceps and triceps brachii muscles are used for control of the prosthesis. A two site multi-function controller is presented. Two stainless steel bipolar electrode pairs are used to monitor the activities in both muscles. The detected signals are processed by new pre-whitening technique to identify the accurate tension estimation in these muscles. These estimates will activate the relevant prosthesis control signal, with a time constant of 200 msec. It is ensured that the tension states in the control muscle to activate a particular prosthesis function are similar to those used to activate normal functions in the natural hand. This facilitates easier training.Keywords: prosthesis, biosignal processing, pre-whitening, myoelectric controller
Procedia PDF Downloads 3631793 Glycation of Serum Albumin: Cause Remarkable Alteration in Protein Structure and Generation of Early Glycation End Products
Authors: Ishrat Jahan Saifi, Sheelu Shafiq Siddiqi, M. R. Ajmal
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Glycation of protein is very important as well as a harmful process, which may lead to develop DM in human body. Human Serum Albumin (HSA) is the most abundant protein in blood and it is highly prone to glycation by the reducing sugars. 2-¬deoxy d-¬Ribose (dRib) is a highly reactive reducing sugar which is produced in cells as a product of the enzyme thymidine phosphorylase. It is generated during the degradation of DNA in human body. It may cause glycation in HSA rapidly and is involved in the development of DM. In present study, we did in¬vitro glycation of HSA with different concentrations of 2-¬deoxy d-¬ribose and found that dRib glycated HSA rapidly within 4h incubation at 37◦C. UV¬ Spectroscopy, Fluorescence spectroscopy, Fourier transform infrared spectroscopy (FTIR) and Circular Dichroism (CD) technique have been done to determine the structural changes in HSA upon glycation. Results of this study suggested that dRib is the potential glycating agent and it causes alteration in protein structure and biophysical properties which may lead to development and progression of Diabetes mellitus.Keywords: 2-deoxy D-ribose, human serum albumin, glycation, diabetes mellitus
Procedia PDF Downloads 2101792 Failure Analysis of a Hydrocarbon Carrying/Piping System
Authors: Esteban Morales Murillo, Ephraim Mokgothu
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This paper presents the findings of a study conducted to investigate the wall thinning in a piping system carrying a mix of hydrocarbons in a petrochemical plant. A detailed investigation including optical inspection and several characterisation techniques such as optical microscopy, SEM/EDX, and XRF/C-S analyses was conducted. The examinations revealed that the wall thinning in the piping system was a result of high-temperature H2/H2S corrosion caused by a susceptible material for this mechanism and operating parameters and effluent concentrations beyond the prescribed limits. The sulfide layers found to testify to the large amounts of H2S that led to material degradation. Deposit analysis revealed that it consisted primarily of carbon, oxygen, iron, chromium and sulfur. Metallographic examinations revealed that the attack initiated from the internal surface and that spheroidization of carbides did occur. The article discusses in detail the contribution failure factors on the Couper-Gorman H2/H2S curves to draw conclusions. Recommendations based on the above findings are also discussed.Keywords: corrosion, Couper-Gorman, high-temperature corrosion, sulfidation, wall thinning, piping system
Procedia PDF Downloads 3851791 Assessing the Blood-Brain Barrier (BBB) Permeability in PEA-15 Mutant Cat Brain using Magnetization Transfer (MT) Effect at 7T
Authors: Sultan Z. Mahmud, Emily C. Graff, Adil Bashir
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Phosphoprotein enriched in astrocytes 15 kDa (PEA-15) is a multifunctional adapter protein which is associated with the regulation of apoptotic cell death. Recently it has been discovered that PEA-15 is crucial in normal neurodevelopment of domestic cats, a gyrencephalic animal model, although the exact function of PEA-15 in neurodevelopment is unknown. This study investigates how PEA-15 affects the blood-brain barrier (BBB) permeability in cat brain, which can cause abnormalities in tissue metabolite and energy supplies. Severe polymicrogyria and microcephaly have been observed in cats with a loss of function PEA-15 mutation, affecting the normal neurodevelopment of the cat. This suggests that the vital role of PEA-15 in neurodevelopment is associated with gyrification. Neurodevelopment is a highly energy demanding process. The mammalian brain depends on glucose as its main energy source. PEA-15 plays a very important role in glucose uptake and utilization by interacting with phospholipase D1 (PLD1). Mitochondria also plays a critical role in bioenergetics and essential to supply adequate energy needed for neurodevelopment. Cerebral blood flow regulates adequate metabolite supply and recent findings also showed that blood plasma contains mitochondria as well. So the BBB can play a very important role in regulating metabolite and energy supply in the brain. In this study the blood-brain permeability in cat brain was measured using MRI magnetization transfer (MT) effect on the perfusion signal. Perfusion is the tissue mass normalized supply of blood to the capillary bed. Perfusion also accommodates the supply of oxygen and other metabolites to the tissue. A fraction of the arterial blood can diffuse to the tissue, which depends on the BBB permeability. This fraction is known as water extraction fraction (EF). MT is a process of saturating the macromolecules, which has an effect on the blood that has been diffused into the tissue while having minimal effect on intravascular blood water that has not been exchanged with the tissue. Measurement of perfusion signal with and without MT enables to estimate the microvascular blood flow, EF and permeability surface area product (PS) in the brain. All the experiments were performed with Siemens 7T Magnetom with 32 channel head coil. Three control cats and three PEA-15 mutant cats were used for the study. Average EF in white and gray matter was 0.9±0.1 and 0.86±0.15 respectively, perfusion in white and gray matter was 85±15 mL/100g/min and 97±20 mL/100g/min respectively, PS in white and gray matter was 201±25 mL/100g/min and 225±35 mL/100g/min respectively for control cats. For PEA-15 mutant cats, average EF in white and gray matter was 0.81±0.15 and 0.77±0.2 respectively, perfusion in white and gray matter was 140±25 mL/100g/min and 165±18 mL/100g/min respectively, PS in white and gray matter was 240±30 mL/100g/min and 259±21 mL/100g/min respectively. This results show that BBB is compromised in PEA-15 mutant cat brain, where EF is decreased and perfusion as well as PS are increased in the mutant cats compared to the control cats. This findings might further explain the function of PEA-15 in neurodevelopment.Keywords: BBB, cat brain, magnetization transfer, PEA-15
Procedia PDF Downloads 1431790 Natural Preservatives: An Alternative for Chemical Preservative Used in Foods
Authors: Zerrin Erginkaya, Gözde Konuray
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Microbial degradation of foods is defined as a decrease of food safety due to microorganism activity. Organic acids, sulfur dioxide, sulfide, nitrate, nitrite, dimethyl dicarbonate and several preservative gases have been used as chemical preservatives in foods as well as natural preservatives which are indigenous in foods. It is determined that usage of herbal preservatives such as blueberry, dried grape, prune, garlic, mustard, spices inhibited several microorganisms. Moreover, it is determined that animal origin preservatives such as whey, honey, lysosomes of duck egg and chicken egg, chitosan have antimicrobial effect. Other than indigenous antimicrobials in foods, antimicrobial agents produced by microorganisms could be used as natural preservatives. The antimicrobial feature of preservatives depends on the antimicrobial spectrum, chemical and physical features of material, concentration, mode of action, components of food, process conditions, and pH and storage temperature. In this review, studies about antimicrobial components which are indigenous in food (such as herbal and animal origin antimicrobial agents), antimicrobial materials synthesized by microorganisms, and their usage as an antimicrobial agent to preserve foods are discussed.Keywords: animal origin preservatives, antimicrobial, chemical preservatives, herbal preservatives
Procedia PDF Downloads 3771789 Formulation of a Submicron Delivery System including a Platelet Lysate to Be Administered in Damaged Skin
Authors: Sergio A. Bernal-Chavez, Sergio Alcalá-Alcalá, Doris A. Cerecedo-Mercado, Adriana Ganem-Rondero
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The prevalence of people with chronic wounds has increased dramatically by many factors including smoking, obesity and chronic diseases, such as diabetes, that can slow the healing process and increase the risk of becoming chronic. Because of this situation, the improvement of chronic wound treatments is a necessity, which has led to the scientific community to focus on improving the effectiveness of current therapies and the development of new treatments. The wound formation is a physiological complex process, which is characterized by an inflammatory stage with the presence of proinflammatory cells that create a proteolytic microenvironment during the healing process, which includes the degradation of important growth factors and cytokines. This decrease of growth factors and cytokines provides an interesting strategy for wound healing if they are administered externally. The use of nanometric drug delivery systems, such as polymer nanoparticles (NP), also offers an interesting alternative around dermal systems. An interesting strategy would be to propose a formulation based on a thermosensitive hydrogel loaded with polymeric nanoparticles that allows the inclusion and application of a platelet lysate (PL) on damaged skin, with the aim of promoting wound healing. In this work, NP were prepared by a double emulsion-solvent evaporation technique, using polylactic-co-glycolic acid (PLGA) as biodegradable polymer. Firstly, an aqueous solution of PL was emulsified into a PLGA organic solution, previously prepared in dichloromethane (DCM). Then, this disperse system (W/O) was poured into a polyvinyl alcohol (PVA) solution to get the double emulsion (W/O/W), finally the DCM was evaporated by magnetic stirring resulting in the NP formation containing PL. Once the NP were obtained, these systems were characterized by morphology, particle size, Z-potential, encapsulation efficiency (%EE), physical stability, infrared spectrum, calorimetric studies (DSC) and in vitro release profile. The optimized nanoparticles were included in a thermosensitive gel formulation of Pluronic® F-127. The gel was prepared by the cold method at 4 °C and 20% of polymer concentration. Viscosity, sol-gel phase transition, time of no flow solid-gel at wound temperature, changes in particle size by temperature-effect using dynamic light scattering (DLS), occlusive effect, gel degradation, infrared spectrum and micellar point by DSC were evaluated in all gel formulations. PLGA NP of 267 ± 10.5 nm and Z-potential of -29.1 ± 1 mV were obtained. TEM micrographs verified the size of NP and evidenced their spherical shape. The %EE for the system was around 99%. Thermograms and in infrared spectra mark the presence of PL in NP. The systems did not show significant changes in the parameters mentioned above, during the stability studies. Regarding the gel formulation, the transition sol-gel occurred at 28 °C with a time of no flow solid-gel of 7 min at 33°C (common wound temperature). Calorimetric, DLS and infrared studies corroborated the physical properties of a thermosensitive gel, such as the micellar point. In conclusion, the thermosensitive gel described in this work, contains therapeutic amounts of PL and fulfills the technological properties to be used in damaged skin, with potential application in wound healing and tissue regeneration.Keywords: growth factors, polymeric nanoparticles, thermosensitive hydrogels, tissue regeneration
Procedia PDF Downloads 1721788 Land Use Changes and Impact around Maladumba Lake and Forest Reserve, Nigeria
Authors: M. B. Abdullahi, S. M. Gumel
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This study was carried out to analyze and describe biodiversity changes in representative communities around Maladumba Lake and Forest Reserve (MLFR), Bauchi, Nigeria. Primary and secondary data were collected through formal and informal interviews of key informants and survey of local communities and government records. There has been a change in biodiversity; some of the cropping systems have become nonexistent whereas others have developed. The main aspect of the changes has been the decline of species diversity due to degradation and over utilization. The changes have also been positive through the introduction and intensification of cropping system. Options have been open for people to manipulate the cropping systems in order to efficiently use the limited resources. Farmers have opted not only to intensify agricultural practices but also to deliberately restore some of the lost species. Reduction in the number of animals per household, adoption of new techniques of land management, changes in the type of crops cultivated and intensive use of the available resources are some of the indicators describing farmers’ efforts to cope with the changes. Sustainability of the farming system and biodiversity has been enhanced through peoples’ efforts that include planting trees and use of fertilizers.Keywords: cropping systems, historical trends, household, land management, sustainability
Procedia PDF Downloads 3941787 Two Layer Photo-Thermal Deflection Model to Investigate the Electronic Properties in BGaAs/GaAs Alloys
Authors: S. Ilahi, M. Baira, F. Saidi, N. Yacoubi, L. Auvray, H. Maaref
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Photo-thermal deflection technique (PTD) is used to study the nonradiative recombination process in BGaAs/GaAs alloy with boron composition of 3% and 8% grown by metal organic chemical vapor deposition (MOCVD). A two layer theoretical model has been developed taking into account both thermal and electronic contribution in the photothermal signal allowing to extract the electronic parameters namely electronic diffusivity, surface and interface recombination. It is found that the increase of boron composition alters the BGaAs epilayers transport properties.Keywords: photothermal defelction technique, two layer model, BGaAs/GaAs alloys, boron composition
Procedia PDF Downloads 3011786 Software Improvements of the Accuracy in the Air-Electronic Measurement Systems for Geometrical Dimensions
Authors: Miroslav H. Hristov, Velizar A. Vassilev, Georgi K. Dukendjiev
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Due to the constant development of measurement systems and the aim for computerization, unavoidable improvements are made for the main disadvantages of air gauges. With the appearance of the air-electronic measuring devices, some of their disadvantages are solved. The output electrical signal allows them to be included in the modern systems for measuring information processing and process management. Producer efforts are aimed at reducing the influence of supply pressure and measurement system setup errors. Increased accuracy requirements and preventive error measures are due to the main uses of air electronic systems - measurement of geometric dimensions in the automotive industry where they are applied as modules in measuring systems to measure geometric parameters, form, orientation and location of the elements.Keywords: air-electronic, geometrical parameters, improvement, measurement systems
Procedia PDF Downloads 2261785 Production of Linamarase from Lactobacillus delbrueckii NRRL B-763
Authors: Ogbonnaya Nwokoro, Florence O. Anya
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Nutritional factors relating to the production of linamarase from Lactobacillus delbrueckii NRRL B–763 were investigated. The microorganism was cultivated in a medium containing 1% linamarin. Enzyme was produced using a variety of carbon substrates but the highest enzyme activity was detected in the presence of salicin (522 U/ml) after 48 h while the lowest yield was observed with CM cellulose (38 U/ml) after 72 h. Enzyme was not produced in the presence of cellobiose. Among a variety of nitrogen substrates tested, peptone supported maximum enzyme production (412 U/ml) after 48 h. Lowest enzyme production was observed with urea (40 U/ml). Organic nitrogen substrates generally supported higher enzyme productivity than inorganic nitrogen substrates. Enzyme activity was observed in the presence of Mn2+ (% relative activity = 216) while Hg2+ was inhibitory (% relative activity = 28). Locally-formulated media were comparable to MRS broth in supporting linamarase production by the bacterium. Higher enzyme activity was produced in media with surfactant than in media without surfactant. The enzyme may be useful in enhanced degradation of cassava cyanide.Keywords: linamarase, locally formulated media, carbon substrates, nitrogen substrates, metal ions
Procedia PDF Downloads 4271784 Power HEMTs Transistors for Radar Applications
Authors: A. boursali, A. Guen Bouazza, M. Khaouani, Z. Kourdi, B. Bouazza
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This paper presents the design, development and characterization of the devices simulation for X-Band Radar applications. The effect of an InAlN/GaN structure on the RF performance High Electron Mobility Transistor (HEMT) device. Systematic investigations on the small signal as well as power performance as functions of the drain biases are presented. Were improved for X-band applications. The Power Added Efficiency (PAE) was achieved over 23% for X-band. The developed devices combine two InAlN/GaN HEMTs of 30nm gate periphery and exhibited the output power of over 50W. An InAlN/GaN HEMT with 30nm gate periphery was developed and exhibited the output power of over 120W.Keywords: InAlN/GaN, HEMT, RF analyses, PAE, X-Band, radar
Procedia PDF Downloads 5601783 Changes in Physical Soil Properties and Crop Status on Soil Enriched With Treated Manure
Authors: Vaclav Novak, Katerina Krizova, Petr Sarec
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Modern agriculture has to face many issues from which soil degradation and lack of organic matter in the soil are only a few of them. Apart from Climate Change, human utilization of landscape is the cause of a majority part of these problems. Cattle production in Czechia has been reduced by more than half in recent 30 years. However, cattle manure is considered as staple organic fertilizer, and its role in attempts for sustainable agriculture is irreplaceable. This study aims to describe the impact of so-called activators of biological manure transformation (Z´fix, Olmix Group) mainly on physical soil properties but also on crop status. The experiment has been established in 2017; nevertheless, initial measurements of implement draft have been performed before the treated manure application. In 2018, the physical soil properties and crop status (sugar beet) has been determined and compared with the untreated manure and control variant. Significant results have been observed already in the first year, where the implement draft decreased by 9.2 % within the treated manure variant in comparison with the control variant.Keywords: field experiment, implement draft, vegetation index, sugar beet
Procedia PDF Downloads 1561782 Anti-Oxidant and Anti-Bacterial Properties of Camellia sinensis, Tea Plant
Authors: Rini Jarial, Puranjan Mishra, Lakhveer Singh, Sveta Thakur, A. W. Zularisam, Mimi Sakinah
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The aim of the present study was to assess the biological properties of Camellia sinensis and to identify its functional compounds. The methanolic leaves-extract (MLE) of commercial green tea (Camellia sinensis) was assessed for anti-bacterial activities by measuring inhibition zones against a panel of pathogenic bacterial strains using agar diffusion method. The flavonoid (5.0 to 8.0 mg/ml) and protein content (10 to 15 mg/ml) of the MLE were recorded. MLE at a concentration of 25 μg/ml showed marked anti-bacterial activity against all bacterial strains (11-30 mm zone of inhibition) and was maximum against Staphylococcus aureus (30 mm). The MLE of Camellia sinensis had the best MIC values of 2.25 and 0.56 mg/ml against S. aureus and Enterobacter sp., respectively. The MLE also possessed good anti-lipolytic activity (65%) against a Porcine pancreatic lipase (PPL) and cholesterol oxidase inhibition (79%). The present study provided strong experimental evidences that the MLE of Camellia sinensis is not only a potent source of natural anti-oxidants and anti-bacterial activity but also possesses efficient cholesterol degradation and anti-lipolytic activities that might be beneficial in the body weight management.Keywords: anti-oxidant, anti-bacterial activity, anti-lipolytic activity, Camellia sinensis, phyto-chemicals
Procedia PDF Downloads 291