Search results for: splitter plate
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 436

Search results for: splitter plate

166 Enhancement of Impingement Heat Transfer on a Flat Plate with Ribs

Authors: M. Kito, M. Takezaki, T. Shakouchi, K. Tsujimoto, T. Ando

Abstract:

Impinging jets are widely used in industrial cooling systems for their high heat transfer characteristics at stagnation points. However, the heat transfer characteristics are low in the downstream direction. In order to improve the heat transfer coefficient further downstream, investigations introducing ribs on jet-cooled flat plates have been conducted. Most studies regarding the heat-transfer enhancement using a rib-roughened wall have dealt with the rib pitch. In this paper, we focused on the rib spacing and demonstrated that the rib spacing must be more than 6 times the nozzle width to improve heat transfer at Reynolds number Re=5.0×103 because it is necessary to have enough space to allow reattachment of flow behind the first rib.

Keywords: Forced convection, heat transfer, impinging jet cooling, rib roughened wall

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165 Axisymmetric Nonlinear Analysis of Point Supported Shallow Spherical Shells

Authors: M. Altekin, R. F. Yükseler

Abstract:

Geometrically nonlinear axisymmetric bending of a shallow spherical shell with a point support at the apex under linearly varying axisymmetric load was investigated numerically. The edge of the shell was assumed to be simply supported or clamped. The solution was obtained by the finite difference and the Newton-Raphson methods. The thickness of the shell was considered to be uniform and the material was assumed to be homogeneous and isotropic. Sensitivity analysis was made for two geometrical parameters. The accuracy of the algorithm was checked by comparing the deflection with the solution of point supported circular plates and good agreement was obtained.

Keywords: Bending, nonlinear, plate, point support, shell.

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164 Early Installation Effect on the Vibration Generated by Machines

Authors: Maitham Al-Safwani

Abstract:

Motor vibration issues were analyzed and correlated to poor equipment installation. We had a water injection pump tested in the factory and exceeded the pump vibration limit. Once the pump was brought to the site, its half-size shim plates were replaced with full-size shims plate that drastically reduced the vibration. In this study, vibration data were recorded for several and similar motors run at the same and different speeds. The vibration values were recorded — for two and a half hours — and the vibration readings analyzed to determine when the readings become consistent. This was as well supported by recording the audio noises produced by some machines seeking a relationship between changes in machine noises and machine abnormalities, such as vibration.

Keywords: Vibration, noise, shaft unbalance, shaft misalignment.

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163 The Effect of Screw Parameters on Pullout Strength of Screw Fixation in Cervical Spine

Authors: S. Ritddech, P. Aroonjarattham, K. Aroonjarattham

Abstract:

The pullout strength had an effect on the stability of plate screw fixation when inserted in the cervical spine. Nine different titanium alloy bone screws were used to test the pullout strength through finite element analysis. The result showed that the Moss Miami I can bear the highest pullout force at 1,075 N, which causes the maximum von Mises stress at 858.87 MPa, a value over the yield strength of titanium. The bone screw should have large outer diameter, core diameter and proximal root radius to increase the pullout strength.

Keywords: Pullout strength, Screw parameter, Cervical spine, Finite element analysis.

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162 Analytical Study and Modeling of Free Vibrations of Functionally Graded Plates Using a Higher Shear Deformation Theory

Authors: A. Meftah, D. Zarga, M. Yahiaoui

Abstract:

In this paper, we have used an analytical method to analyze the vibratory behavior of plates in materials with gradient of properties, simply supported, proposing a refined non polynomial theory. The number of unknown functions involved in this theory is only four, as compared to five in the case of other higher shear deformation theories. The transverse shearing effects are studied according to the thickness of the plate. The motion equations for the FGM plates are obtained by the Hamilton principle application, the solutions are obtained using the Navier method, and then the fundamental frequencies are found, solving an eigenvalue equation system, the results of this analysis are presented and compared to those available in the literature.

Keywords: FGM plates, Navier method, vibratory behavior.

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161 Boundary Effect on the Onset of Marangoni Convection with Internal Heat Generation

Authors: Norihan Md Arifin, Norfifah Bachok

Abstract:

The onset of Marangoni convection in a horizontal fluid layer with internal heat generation overlying a solid layer heated from below is studied. The upper free surface of a fluid is nondeformable and the bottom boundary are rigid and no-slip. The resulting eigenvalue problem is solved exactly. The critical values of the Marangoni numbers for the onset of Marangoni convection are calculated and the latter is found to be critically dependent on the internal heating, depth ratio and conductivity ratio. The effects of the thermal conductivity and the thickness of the solid plate on the onset of convective instability with internal heating are studied in detail.

Keywords: Linear stability, Marangoni convection, Internal Heatgeneration.

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160 Development of an Infrared Thermography Method with CO2 Laser Excitation, Applied to Defect Detection in CFRP

Authors: Sam-Ang Keo, Franck Brachelet, Florin Breaban, Didier Defer

Abstract:

This paper presents a NDT by infrared thermography with excitation CO2 Laser, wavelength of 10.6 μm. This excitation is the controllable heating beam, confirmed by a preliminary test on a wooden plate 1.2 m x 0.9 m x 1 cm. As the first practice, this method is applied to detecting the defect in CFRP heated by the Laser 300 W during 40 s. Two samples 40 cm x 40 cm x 4.5 cm are prepared, one with defect, another one without defect. The laser beam passes through the lens of a deviation device, and heats the samples placed at a determinate position and area. As a result, the absence of adhesive can be detected. This method displays prominently its application as NDT with the composite materials. This work gives a good perspective to characterize the laser beam, which is very useful for the next detection campaigns.

Keywords: CO2 LASER, Infrared Thermography, NDT, CFRP, Defect Detection.

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159 Investigation on Choosing the Suitable Geometry of the Solar Air Heater to Certain Conditions

Authors: Abdulrahman M. Homadi

Abstract:

This study focuses on how to control the outlet temperature of a solar air heater in a way simpler than the existing methods. In this work, five cases have been studied by using ANSYS Fluent based on a CFD numerical method. All the cases have been simulated by utilizing the same criteria and conditions like the temperature, materials, areas except the geometry. The case studies are conducted in Little Rock (LR), AR, USA during the winter time supposedly on 15th of December. A fresh air that is flowing with a velocity of 0.5 m/s and a flow rate of 0.009 m3/s. The results prove the possibility of achieving a controlled temperature just by changing the geometric shape of the heater. This geometry guarantees that the absorber plate always has a normal component of the solar radiation at any time during the day. The heater has a sectarian shape with a radius of 150 mm where the outlet temperature remains almost constant for six hours.

Keywords: Solar energy, air heater, control of temperature, CFD.

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158 From “Boat to Plate”: Creating Value through Sustainable Fish Supply Chain Visibility

Authors: Isabel Duarte de Almeida, João Vilas-Boas, Luís Miguel Ferreira

Abstract:

Environmental concerns about the scarcity of marine resources are critical driving forces for firms aiming to prepare their supply chains for sustainability. Building on previous work, this paper highlights the implementation of good practices geared towards sustainable operations in the seafood department, which were pursued in an exploratory retailer case. Outcomes of the adopted environmentally and socially acceptable fish retailing strategies, ranged from traceability, to self-certification and eco-labelling. The consequences for business were, as follows: stronger collaboration and trust across the chain of custody, improvement of sponsors’ image and of consumers’ loyalty and, progress in the Greenpeace retailers’ evaluation ranking.

Keywords: Sustainability in sea food, Supply Chain Traceability, Social Responsibility.

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157 Microbiological Quality and Safety of Meatball Sold in Payakumbuh City, West Sumatra, Indonesia

Authors: Ferawati, H. Purwanto, Y. F. Kurnia, E. Purwati

Abstract:

The aim of this study was to evaluate the microbiological quality and safety of meatball obtained from five different manufacturers around Payakumbuh City, West Sumatra, Indonesia. Microbiological analysis of meatball sample resulted in aerobic plate count range from 7 log CFU/gr to 8.623 log CFU/gr, respectively. Total coliform ranges from 1.041 log Most Probable Number (MPN)/gr to 3.380 log MPN/gr, respectively. Chemical analysis of meatball sample consisted of borax and formalin content. The result of qualitative detection of borax and formalin content on all meatball samples were not detected. Thus, it remains essential to include the significance of effective hygiene practices as an important safety measure in consumer education programmes.

Keywords: Borax, formalin, meatball, microbiological quality.

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156 Introduction of the Fluid-Structure Coupling into the Force Analysis Technique

Authors: Océane Grosset, Charles Pézerat, Jean-Hugh Thomas, Frédéric Ablitzer

Abstract:

This paper presents a method to take into account the fluid-structure coupling into an inverse method, the Force Analysis Technique (FAT). The FAT method, also called RIFF method (Filtered Windowed Inverse Resolution), allows to identify the force distribution from local vibration field. In order to only identify the external force applied on a structure, it is necessary to quantify the fluid-structure coupling, especially in naval application, where the fluid is heavy. This method can be decomposed in two parts, the first one consists in identifying the fluid-structure coupling and the second one to introduced it in the FAT method to reconstruct the external force. Results of simulations on a plate coupled with a cavity filled with water are presented.

Keywords: Fluid-structure coupling, inverse methods, naval, vibrations.

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155 Modeling and Investigation of Elongation in Free Explosive Forming of Aluminum Alloy Plate

Authors: R. Alipour, F.Najarian

Abstract:

Because of high ductility, aluminum alloys, have been widely used as an important base of metal forming industries. But the main week point of these alloys is their low strength so in forming them with conventional methods like deep drawing, hydro forming, etc have been always faced with problems like fracture during of forming process. Because of this, recently using of explosive forming method for forming of these plates has been recommended. In this paper free explosive forming of A2024 aluminum alloy is numerically simulated and during it, explosion wave propagation process is studied. Consequences of this simulation can be effective in prediction of quality of production. These consequences are compared with an experimental test and show the superiority of this method to similar methods like hydro forming and deep drawing.

Keywords: Free explosive forming, CEL, Johnson cook.

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154 Innovative Techniques for Characterization of Nonwoven Insulation Materials Embedded with Aerogel

Authors: Mohanapriya Venkataraman, Rajesh Mishra, Jakub Weiner, Adnan Mazari, Jiri Militky, Veera Kumar Arumugam

Abstract:

The major objective of this study is to understand the potential of a newly fabricated equipment to study the thermal properties of nonwoven textile fabrics treated with aerogel at subzero temperatures. Thermal conductivity was calculated by using the empirical relation Fourier’s law, The relationship between the thermal conductivity and thermal resistance of the samples were studied at various environmental temperatures (which was set in the clima temperature system between +25oC to -25oC). The newly fabricated equipment was found to be a suitable for measuring at subzero temperatures. This field of measurements is being developed and will be the subject of further research which will be more suitable for measurement of the various thermal characteristics.

Keywords: Thermal Measurements, Aerogel, Nonwoven, Hot plate Heading.

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153 Transient Heat Transfer Model for Car Body Primer Curing

Authors: D. Zabala, N. Sánchez, J. Pinto

Abstract:

A transient heat transfer mathematical model for the prediction of temperature distribution in the car body during primer baking has been developed by considering the thermal radiation and convection in the furnace chamber and transient heat conduction governing equations in the car framework. The car cockpit is considered like a structure with six flat plates, four vertical plates representing the car doors and the rear and front panels. The other two flat plates are the car roof and floor. The transient heat conduction in each flat plate is modeled by the lumped capacitance method. Comparison with the experimental data shows that the heat transfer model works well for the prediction of thermal behavior of the car body in the curing furnace, with deviations below 5%.

Keywords: Transient heat transfer, car body, lumpedcapacitance, primer baking.

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152 Prediction Method of Extenics Theory for Assessment of Bearing Capacity of Lateritic Soil Foundation

Authors: Wei Bai, Ling-Wei Kong, Ai-Guo Guo

Abstract:

Base on extenics theory, the statistical physical and mechanical properties from laboratory experiments are used to evaluate the bearing capacity of lateritic soil foundation. The properties include water content, bulk density, liquid limit, cohesion, and so on. The matter-element and the dependent function are defined. Then the synthesis dependent degree and the final grade index are calculated. The results show that predicted outcomes can be matched with the in-situ test data, and a evaluate grade associate with bearing capacity can be deduced. The results provide guidance to assess and determine the bearing capacity grade of lateritic soil foundation.

Keywords: Lateritic soil, bearing capacity, extenics theory, plate loading test.

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151 A Semi-Cylindrical Capacitive Sensor Used for Soil Moisture Measurement

Authors: Subir Das, Tuhin Subhra Sarkar, Badal Chakraborty

Abstract:

Differing from the structure of traditional parallel plate capacitive sensor a semi cylindrical capacitive sensor has been introduced in this present work to measure the soil moisture conveniently. Here, the numerical analysis method to evaluate the capacitance from the semi-cylindrical capacitive sensor is analyzed and discussed. The changes of capacitance with the variation of soil moisture obtained linear in the nano farad range (nF) and which converted into voltage variation by using proper signal conditioning circuit. Experimental results depict the satisfactory performance of the sensor for measurement of soil moisture in the range of 0 to 70%. We investigated the linearity of 4% of FSO and sensitivity of 70 mV/unit percentage changes in soil moisture level (DB).

Keywords: Semi cylindrical Capacitive Sensor, Capacitance to Voltage converter Circuit, Soil Moisture.

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150 Study of the Effect of Inclusion of TiO2 in Active Flux on Submerged Arc Welding of Low Carbon Mild Steel Plate and Parametric Optimization of the Process by Using DEA Based Bat Algorithm

Authors: Sheetal Kumar Parwar, J. Deb Barma, A. Majumder

Abstract:

Submerged arc welding is a very complex process. It is a very efficient and high performance welding process. In this present study an attempt have been done to reduce the welding distortion by increased amount of oxide flux through TiO2 in submerged arc welding process. Care has been taken to avoid the excessiveness of the adding agent for attainment of significant results. Data Envelopment Analysis (DEA) based BAT algorithm is used for the parametric optimization purpose in which DEA is used to convert multi response parameters into a single response parameter. The present study also helps to know the effectiveness of the addition of TiO2 in active flux during submerged arc welding process.

Keywords: BAT algorithm, design of experiment, optimization, submerged arc welding.

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149 Machine Learning Development Audit Framework: Assessment and Inspection of Risk and Quality of Data, Model and Development Process

Authors: Jan Stodt, Christoph Reich

Abstract:

The usage of machine learning models for prediction is growing rapidly and proof that the intended requirements are met is essential. Audits are a proven method to determine whether requirements or guidelines are met. However, machine learning models have intrinsic characteristics, such as the quality of training data, that make it difficult to demonstrate the required behavior and make audits more challenging. This paper describes an ML audit framework that evaluates and reviews the risks of machine learning applications, the quality of the training data, and the machine learning model. We evaluate and demonstrate the functionality of the proposed framework by auditing an steel plate fault prediction model.

Keywords: Audit, machine learning, assessment, metrics.

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148 Development of the Measurement Apparatus for the Effective Thermal Conductivity of Core Material

Authors: Jongmin Kim, Tae-Ho Song

Abstract:

A measurement apparatus is designed and fabricated to measure the effective thermal conductivity (keff) of a VIP (vacuum insulation panel) core specimen under various vacuum states and external loads. The apparatus consists of part for measuring keff, and parts for controlling external load and vacuum condition. Uncertainty of the apparatus is validated by measuring the standard reference material and comparing with commercial devices with VIP samples. Assessed uncertainty is maximum 2.5 % in case of the standard reference material, 10 % in case of VIP samples. Using the apparatus, keff of glass paper under various vacuum levels is examined.

Keywords: Effective thermal conductivity, guarded hot plate method, vacuum insulation panel

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147 The Effect of Impact on the Knee Joint Due to the Shocks during Double Impact Phase of Gait Cycle

Authors: Jobin Varghese, V. M. Akhil, P. K. Rajendrakumar, K. S. Sivanandan

Abstract:

The major contributor to the human locomotion is the knee flexion and extension. During heel strike, a huge amount of energy is transmitted through the leg towards knee joint, which in fact is damped at heel and leg muscles. During high shocks, although it is damped to a certain extent, the balance force transmits towards knee joint which could damage the knee. Due to the vital function of the knee joint, it should be protected against damage due to additional load acting on it. This work concentrates on the development of spring mass damper system which exactly replicates the stiffness at the heel and muscles and the objective function is optimized to minimize the force acting at the knee joint. Further, the data collected using force plate are put into the model to verify its integrity and are found to be in good agreement.

Keywords: Spring, mass, damper, impact, knee joint.

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146 Interface Analysis of Annealed Al/Cu Cladded Sheet

Authors: Joon Ho Kim, Tae Kwon Ha

Abstract:

Effect of aging treatment on microstructural aspects of interfacial layers of the Cu/Al clad sheet produced by differential speed rolling (DSR) process were studied by electron back scattered diffraction (EBSD). Clad sheet of Al/Cu has been fabricated by using DSR, which caused severe shear deformation between Al and Cu plate to easily bond to each other. Rolling was carried out at 100oC with speed ratio of 2, in which the total thickness reduction was 45%. Interface layers of clad sheet were analyzed by EBSD after subsequent annealing at 400oC for 30 to 120min. With increasing annealing time, thickness of interface layer and fraction of high angle grain boundary were increased and average grain size was decreased.

Keywords: Aluminum/Copper clad sheet, differential speed rolling, interface layer, microstructure, annealing, electron back scattered diffraction.

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145 Direct Design of Steel Bridge Using Nonlinear Inelastic Analysis

Authors: Boo-Sung Koh, Seung-Eock Kim

Abstract:

In this paper, a direct design using a nonlinear inelastic analysis is suggested. Also, this paper compares the load carrying capacity obtained by a nonlinear inelastic analysis with experiment results to verify the accuracy of the results. The allowable stress design results of a railroad through a plate girder bridge and the safety factor of the nonlinear inelastic analysis were compared to examine the safety performance. As a result, the load safety factor for the nonlinear inelastic analysis was twice as high as the required safety factor under the allowable stress design standard specified in the civil engineering structure design standards for urban magnetic levitation railways, which further verified the advantages of the proposed direct design method.

Keywords: Direct design, nonlinear inelastic analysis, residual stress, initial geometric imperfection.

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144 Solar Tracking System Using a Refrigerant as Working Medium for Solar Energy Conversion

Authors: S. Sendhil Kumar, S. N. Vijayan

Abstract:

Utilization of solar energy can be found in various domestic and industrial applications. The performance of any solar collector is largely affected by various parameters such as glazing, absorber plate, top covers, and heating pipes. Technology improvements have brought us another method for conversion of solar energy to direct electricity using solar photovoltaic system. Utilization and extraction of solar energy is the biggest problem in these conversion methods. This paper aims to overcome these problems and take the advantages of available energy from solar by maximizing the utilization through solar tracking system using a refrigerant as a working medium. The use of this tracking system can help increase the efficiency of conversion devices by maximum utilization of solar energy. The dual axis tracking system gives maximum energy output compared to single axis tracking system.

Keywords: Refrigerant, solar collector, solar energy, solar panel, solar tracking.

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143 Stress Ratio and Notch Effect on Fatigue Crack Initiation and Propagation in 2024 Al-alloy

Authors: N. Benachour, A. Hadjoui, M. Benachour, M. Benguediab

Abstract:

This study reports an empirical investigation of fatigue crack initiation and propagation in 2024 T351 aluminium alloy using constant amplitude loading. In initiation stage, local strain approach at the notch was used and in stable propagation stage NASGRO model was applied. In this investigation, the flat plate of double through crack at hole is used. Based on experimental results (AFGROW Database), effect of stress ratio, R, is highlights on fatigue initiation life (FIL) and fatigue crack growth rate (FCGR). The increasing of dimension of hole characterizing the notch effect decrease the fatigue life.

Keywords: Fatigue crack growth, initiation life, Al-Alloy, stressratio, notch effect

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142 The Reliability of the Improved e-N Method for Transition Prediction as Checked by PSE Method

Authors: Caihong Su

Abstract:

Transition prediction of boundary layers has always been an important problem in fluid mechanics both theoretically and practically, yet notwithstanding the great effort made by many investigators, there is no satisfactory answer to this problem. The most popular method available is so-called e-N method which is heavily dependent on experiments and experience. The author has proposed improvements to the e-N method, so to reduce its dependence on experiments and experience to a certain extent. One of the key assumptions is that transition would occur whenever the velocity amplitude of disturbance reaches 1-2% of the free stream velocity. However, the reliability of this assumption needs to be verified. In this paper, transition prediction on a flat plate is investigated by using both the improved e-N method and the parabolized stability equations (PSE) methods. The results show that the transition locations predicted by both methods agree reasonably well with each other, under the above assumption. For the supersonic case, the critical velocity amplitude in the improved e-N method should be taken as 0.013, whereas in the subsonic case, it should be 0.018, both are within the range 1-2%.

Keywords: Boundary layer, e-N method, PSE, Transition

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141 Optimization of Biodiesel Production from Sunflower Oil Using Central Composite Design

Authors: Pascal Mwenge, Jefrey Pilusa, Tumisang Seodigeng

Abstract:

The current study investigated the effect of catalyst ratio and methanol to oil ratio on biodiesel production by using central composite design. Biodiesel was produced by transesterification using sodium hydroxide as a homogeneous catalyst, a laboratory scale reactor consisting of flat bottom flask mounts with a reflux condenser and a heating plate was used to produce biodiesel. Key parameters, including, time, temperature and mixing rate were kept constant at 60 minutes, 60 oC and 600 RPM, respectively. From the results obtained, it was observed that the biodiesel yield depends on catalyst ratio and methanol to oil ratio. The highest yield of 50.65% was obtained at catalyst ratio of 0.5 wt.% and methanol to oil mole ratio 10.5. The analysis of variances of biodiesel yield showed the R Squared value of 0.8387. A quadratic mathematical model was developed to predict the biodiesel yield in the specified parameters ranges.

Keywords: ANOVA, biodiesel, catalyst, CCD, transesterification.

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140 Convective Interactions and Heat Transfer in a Czochralski Melt with a Model Phase Boundary of Two Different Shapes

Authors: R. Faiez, M. Mashhoudi, F. Najafi

Abstract:

Implicit in most large-scale numerical analyses of the crystal growth from the melt is the assumption that the shape and position of the phase boundary are determined by the transport phenomena coupled strongly to the melt hydrodynamics. In the present numerical study, the interface shape-effect on the convective interactions in a Czochralski oxide melt is described. It was demonstrated that thermocapillary flow affects inversely the phase boundaries of distinct shapes. The inhomogenity of heat flux and the location of the stagnation point at the crystallization front were investigated. The forced convection effect on the point displacement at the boundary found to be much stronger for the flat plate interface compared to the cone-shaped one with and without the Marangoni flow.

Keywords: Computer simulation, fluid flow, interface shape, thermocapillary effect.

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139 DNS of a Laminar Separation Bubble

Authors: N. K. Singh, S. Sarkar

Abstract:

Direct numerical simulation (DNS) is used to study the evolution of a boundary layer that was laminar initially followed by separation and then reattachment owing to generation of turbulence. This creates a closed region of recirculation, known as the laminar-separation bubble. The present simulation emulates the flow environment encountered in a modern LP turbine blade, where a laminar separation bubble may occur on the suction surface. The unsteady, incompressible three-dimensional (3-D) Navier-Stokes (NS) equations have been solved over a flat plate in the Cartesian coordinates. The adverse pressure gradient, which causes the flow to separate, is created by a boundary condition. The separated shear layer undergoes transition through appearance of ╬ø vortices, stretching of these create longitudinal streaks. Breakdown of the streaks into small and irregular structures makes the flow turbulent downstream.

Keywords: Adverse pressure gradient, direct numerical simulation, laminar separation bubble.

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138 Air Flows along Perforated Metal Plates with the Heat Transfer

Authors: K. Fraňa, S. Simon

Abstract:

The objective of the paper is a numerical study of heat transfer between perforated metal plates and the surrounding air flows. Different perforation structures can nowadays be found in various industrial products. Besides improving the mechanical properties, the perforations can intensify the heat transfer as well. The heat transfer coefficient depends on a wide range of parameters such as type of perforation, size, shape, flow properties of the surrounding air etc. The paper was focused on three different perforation structures which have been investigated from the point of the view of the production in the previous studies. To determine the heat coefficients and the Nusselt numbers, the numerical simulation approach was adopted. The calculations were performed using the OpenFOAM software. The three-dimensional, unstable, turbulent and incompressible air flow around the perforated surface metal plate was considered.

Keywords: Perforations, convective heat transfers, turbulent flows, numerical simulations.

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137 Assessment of Aminopolyether on 18F-FDG Samples

Authors: Renata L. C. Leão, João E. Nascimento, Natalia C. E. S. Nascimento, Elaine S. Vasconcelos, Mércia L. Oliveira

Abstract:

The quality control procedures of a radiopharmaceutical include the assessment of its chemical purity. The method suggested by international pharmacopeias consists of a thin layer chromatographic run. In this paper, the method proposed by the United States Pharmacopeia (USP) is compared to a direct method to determine the final concentration of aminopolyether in Fludeoxyglucose (18F-FDG) preparations. The approach (no chromatographic run) was achieved by placing the thin-layer chromatography (TLC) plate directly on an iodine vapor chamber. Both methods were validated and they showed adequate results to determine the concentration of aminopolyether in 18F-FDG preparations. However, the direct method is more sensitive, faster and simpler when compared to the reference method (with chromatographic run), and it may be chosen for use in routine quality control of 18F-FDG.

Keywords: Chemical purity, Kryptofix 222, thin layer chromatography, validation.

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