Search results for: recommender agent
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 529

Search results for: recommender agent

349 Designing an Agent-Based Model of SMEs to Assess Flood Response Strategies and Resilience

Authors: C. Li, G. Coates, N. Johnson, M. McGuinness

Abstract:

In the UK, flooding is responsible for significant losses to the economy due to the impact on businesses, the vast majority of which are Small and Medium Enterprises (SMEs). Businesses of this nature tend to lack formal plans to aid their response to and recovery from disruptive events such as flooding. This paper reports on work on how an agent-based model (ABM) is being developed based on interview data gathered from SMEs at-risk of flooding and/or have direct experience of flooding. The ABM will enable simulations to be performed allowing investigations of different response strategies which SMEs may employ to lessen the impact of flooding, thus strengthening their resilience.

Keywords: ABM, Flood response, SMEs, Business continuity.

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348 A New Multi-Target, Multi-Agent Search-and-Rescue Path Planning Approach

Authors: Jean Berger, Nassirou Lo, Martin Noel

Abstract:

Perfectly suited for natural or man-made emergency and disaster management situations such as flood, earthquakes, tornadoes, or tsunami, multi-target search path planning for a team of rescue agents is known to be computationally hard, and most techniques developed so far come short to successfully estimate optimality gap. A novel mixed-integer linear programming (MIP) formulation is proposed to optimally solve the multi-target multi-agent discrete search and rescue (SAR) path planning problem. Aimed at maximizing cumulative probability of successful target detection, it captures anticipated feedback information associated with possible observation outcomes resulting from projected path execution, while modeling agent discrete actions over all possible moving directions. Problem modeling further takes advantage of network representation to encompass decision variables, expedite compact constraint specification, and lead to substantial problem-solving speed-up. The proposed MIP approach uses CPLEX optimization machinery, efficiently computing near-optimal solutions for practical size problems, while giving a robust upper bound obtained from Lagrangean integrality constraint relaxation. Should eventually a target be positively detected during plan execution, a new problem instance would simply be reformulated from the current state, and then solved over the next decision cycle. A computational experiment shows the feasibility and the value of the proposed approach.

Keywords: Search path planning, search and rescue, multi-agent, mixed-integer linear programming, optimization.

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347 Multi-Agent Systems Applied in the Modeling and Simulation of Biological Problems: A Case Study in Protein Folding

Authors: Pedro Pablo González Pérez, Hiram I. Beltrán, Arturo Rojo-Domínguez, Máximo EduardoSánchez Gutiérrez

Abstract:

Multi-agent system approach has proven to be an effective and appropriate abstraction level to construct whole models of a diversity of biological problems, integrating aspects which can be found both in "micro" and "macro" approaches when modeling this type of phenomena. Taking into account these considerations, this paper presents the important computational characteristics to be gathered into a novel bioinformatics framework built upon a multiagent architecture. The version of the tool presented herein allows studying and exploring complex problems belonging principally to structural biology, such as protein folding. The bioinformatics framework is used as a virtual laboratory to explore a minimalist model of protein folding as a test case. In order to show the laboratory concept of the platform as well as its flexibility and adaptability, we studied the folding of two particular sequences, one of 45-mer and another of 64-mer, both described by an HP model (only hydrophobic and polar residues) and coarse grained 2D-square lattice. According to the discussion section of this piece of work, these two sequences were chosen as breaking points towards the platform, in order to determine the tools to be created or improved in such a way to overcome the needs of a particular computation and analysis of a given tough sequence. The backwards philosophy herein is that the continuous studying of sequences provides itself important points to be added into the platform, to any time improve its efficiency, as is demonstrated herein.

Keywords: multi-agent systems, blackboard-based agent architecture, bioinformatics framework, virtual laboratory, protein folding.

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346 Searching for Similar Informational Articles in the Internet Channel

Authors: Sung Ho Ha, Seong Hyeon Joo, Hyun U. Pae

Abstract:

In terms of total online audience, newspapers are the most successful form of online content to date. The online audience for newspapers continues to demand higher-quality services, including personalized news services. News providers should be able to offer suitable users appropriate content. In this paper, a news article recommender system is suggested based on a user-s preference when he or she visits an Internet news site and reads the published articles. This system helps raise the user-s satisfaction, increase customer loyalty toward the content provider.

Keywords: Content classification, content recommendation, customer profiling, documents clustering.

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345 Effects of Coupling Agent on the Properties of Henequen Microfiber (NF) Filled High Density Polyethylene (HDPE) Composites

Authors: Pravin Gaikwad, Prakash Mahanwar

Abstract:

The main objective of incorporating natural fibers such as Henequen microfibers (NF) into the High Density Polyethylene (HDPE) polymer matrix is to reduce the cost and to enhance the mechanical as well as other properties. The Henequen microfibers were chopped manually to 5-7mm in length and added into the polymer matrix at the optimized concentration of 8 wt %. In order to facilitate the link between Henequen microfibers (NF) and HDPE matrix, coupling agent such as Glycidoxy (Epoxy) Functional Methoxy Silane (GPTS) at various concentrations from 0.1%, 0.3%, 0.5%, 0.7%, 0.9% and 1% by weight to the total fibers were added. The tensile strength of the composite increased marginally while % elongation at break of the composites decreased with increase in silane loading by wt %. Tensile modulus and stiffness observed increased at 0.9 wt % GPTS loading. Flexural as well as impact strength of the composite decreased with increase in GPTS loading by weight %. Dielectric strength of the composite also found increased marginally up to 0.5wt % silane loading and thereafter remained constant. 

Keywords: Henequen microfibers (NF), polymer composites, HDPE, coupling agent, GPTS

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344 Universal Kinetic Modeling of RAFT Polymerization using Moment Equations

Authors: Mehdi Salami-Kalajahi, Pejman Ganjeh-Anzabi, Vahid Haddadi-Asl, Mohammad Najafi

Abstract:

In the following text, we show that by introducing universal kinetic scheme, the origin of rate retardation and inhibition period which observed in dithiobenzoate-mediated RAFT polymerization can be described properly. We develop our model by utilizing the method of moments, then we apply our model to different monomer/RAFT agent systems, both homo- and copolymerization. The modeling results are in an excellent agreement with experiments and imply the validity of universal kinetic scheme, not only for dithiobenzoate-mediated systems, but also for different types of monomer/RAFT agent ones.

Keywords: RAFT Polymerization, Mechanism, Kinetics, Moment Equations, Modeling.

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343 Environmental Inspection using WSANs Based on Multi-agent Coordination Method

Authors: Mohammad J. Heydari, Farnaz Derakhshan

Abstract:

In this paper, we focus on the problem of driving and herding a collection of autonomous actors to a given area. Then, a new method based on multi-agent coordination is proposed for solving the problem. In our proposed method, we assume that the environment is covered by sensors. When an event is occurred, sensors forward information to a sink node. Based on received information, the sink node will estimate the direction and the speed of movement of actors and announce the obtained value to the actors. The actors coordinate to reach the target location.

Keywords: Coordination, Environmental Inspection, Multiagent systems, Wireless Sensor and Actor Networks (WSANs)

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342 An Example of Open Robot Controller Architecture - For Power Distribution Line Maintenance Robot System -

Authors: Yingxin He, Kyouichi Tatsuno

Abstract:

In this paper, we propose an architecture for easily constructing a robot controller. The architecture is a multi-agent system which has eight agents: the Man-machine interface, Task planner, Task teaching editor, Motion planner, Arm controller, Vehicle controller, Vision system and CG display. The controller has three databases: the Task knowledge database, the Robot database and the Environment database. Based on this controller architecture, we are constructing an experimental power distribution line maintenance robot system and are doing the experiment for the maintenance tasks, for example, “Bolt insertion task".

Keywords: Robot controller, Software library, Maintenance robot, Robot language, Agent system.

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341 Human Absorbed Dose Estimation of a New IN-111 Imaging Agent Based on Rat Data

Authors: H. Yousefnia, S. Zolghadri

Abstract:

The measurement of organ radiation exposure dose is one of the most important steps to be taken initially, for developing a new radiopharmaceutical. In this study, the dosimetric studies of a novel agent for SPECT-imaging of the bone metastasis, 111In- 1,4,7,10-tetraazacyclododecane-1,4,7,10 tetraethylene phosphonic acid (111In-DOTMP) complex, have been carried out to estimate the dose in human organs based on the data derived from rats. The radiolabeled complex was prepared with high radiochemical purity in the optimal conditions. Biodistribution studies of the complex was investigated in the male Syrian rats at selected times after injection (2, 4, 24 and 48 h). The human absorbed dose estimation of the complex was made based on data derived from the rats by the radiation absorbed dose assessment resource (RADAR) method. 111In-DOTMP complex was prepared with high radiochemical purity of >99% (ITLC). Total body effective absorbed dose for 111In- DOTMP was 0.061 mSv/MBq. This value is comparable to the other 111In clinically used complexes. The results show that the dose with respect to the critical organs is satisfactory within the acceptable range for diagnostic nuclear medicine procedures. Generally, 111In- DOTMP has interesting characteristics and can be considered as a viable agent for SPECT-imaging of the bone metastasis in the near future.

Keywords: In-111, DOTMP, Internal Dosimetry, RADAR.

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340 A Novel Hybrid Mobile Agent Based Distributed Intrusion Detection System

Authors: Amir Vahid Dastjerdi, Kamalrulnizam Abu Bakar

Abstract:

The first generation of Mobile Agents based Intrusion Detection System just had two components namely data collection and single centralized analyzer. The disadvantage of this type of intrusion detection is if connection to the analyzer fails, the entire system will become useless. In this work, we propose novel hybrid model for Mobile Agent based Distributed Intrusion Detection System to overcome the current problem. The proposed model has new features such as robustness, capability of detecting intrusion against the IDS itself and capability of updating itself to detect new pattern of intrusions. In addition, our proposed model is also capable of tackling some of the weaknesses of centralized Intrusion Detection System models.

Keywords: Distributed Intrusion Detection System, Mobile Agents, Network Security.

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339 On the Continuous Service of Distributed e-Learning System

Authors: Kazunari Meguro, Shinichi Motomura, Takao Kawamura, Kazunori Sugahara

Abstract:

In this paper, backup and recovery technique for Peer to Peer applications, such as a distributed asynchronous Web-Based Training system that we have previously proposed. In order to improve the scalability and robustness of this system, all contents and function are realized on mobile agents. These agents are distributed to computers, and they can obtain using a Peer to Peer network that modified Content-Addressable Network. In the proposed system, although entire services do not become impossible even if some computers break down, the problem that contents disappear occurs with an agent-s disappearance. As a solution for this issue, backups of agents are distributed to computers. If a failure of a computer is detected, other computers will continue service using backups of the agents belonged to the computer.

Keywords: Distributed Multimedia Systems, e-Learning, P2P, Mobile Agent

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338 Analyzing the Relation of Community Group for Research Paper Bookmarking by Using Association Rule

Authors: P. Jomsri

Abstract:

Currently searching through internet is very popular especially in a field of academic. A huge of educational information such as research papers are overload for user. So community-base web sites have been developed to help user search information more easily from process of customizing a web site to need each specifies user or set of user. In this paper propose to use association rule analyze the community group on research paper bookmarking. A set of design goals for community group frameworks is developed and discussed. Additionally Researcher analyzes the initial relation by using association rule discovery between the antecedent and the consequent of a rule in the groups of user for generate the idea to improve ranking search result and development recommender system.

Keywords: association rule, information retrieval, research paper bookmarking.

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337 Coordination on Agrifood Supply Chain

Authors: Martha Liliana Reina Usuga, Wilson Adarme Jaimes, Oscar Eduardo Suarez

Abstract:

Coordinated supply chain represents major challenges for the different actors involved in it, because each agent responds to individual interests. The paper presents a framework with the reviewed literature regarding the system's decision structure and nature of demand. Later, it characterizes an agri food supply chain in the Central Region of Colombia, it responds to a decentralized distribution system and a stochastic demand. Finally, the paper recommends coordinating the chain based on shared information, and mechanisms for each agent, as VMI (vendor-managed inventory) strategy for farmer-buyer relationship, information system for farmers and contracts for transportation service providers.

Keywords: Agri-food supply chain, Coordination mechanisms, Decentralized distribution system, Supply chain coordination.

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336 An Agent Oriented Approach to Operational Profile Management

Authors: Sunitha Ramanujam, Hany El Yamany, Miriam A. M. Capretz

Abstract:

Software reliability, defined as the probability of a software system or application functioning without failure or errors over a defined period of time, has been an important area of research for over three decades. Several research efforts aimed at developing models to improve reliability are currently underway. One of the most popular approaches to software reliability adopted by some of these research efforts involves the use of operational profiles to predict how software applications will be used. Operational profiles are a quantification of usage patterns for a software application. The research presented in this paper investigates an innovative multiagent framework for automatic creation and management of operational profiles for generic distributed systems after their release into the market. The architecture of the proposed Operational Profile MAS (Multi-Agent System) is presented along with detailed descriptions of the various models arrived at following the analysis and design phases of the proposed system. The operational profile in this paper is extended to comprise seven different profiles. Further, the criticality of operations is defined using a new composed metrics in order to organize the testing process as well as to decrease the time and cost involved in this process. A prototype implementation of the proposed MAS is included as proof-of-concept and the framework is considered as a step towards making distributed systems intelligent and self-managing.

Keywords: Software reliability, Software testing, Metrics, Distributed systems, Multi-agent systems

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335 Using Emotional Learning in Rescue Simulation Environment

Authors: Maziar Ahmad Sharbafi, Caro Lucas, Abolfazel Toroghi Haghighat, Omid AmirGhiasvand, Omid Aghazade

Abstract:

RoboCup Rescue simulation as a large-scale Multi agent system (MAS) is one of the challenging environments for keeping coordination between agents to achieve the objectives despite sensing and communication limitations. The dynamicity of the environment and intensive dependency between actions of different kinds of agents make the problem more complex. This point encouraged us to use learning-based methods to adapt our decision making to different situations. Our approach is utilizing reinforcement leaning. Using learning in rescue simulation is one of the current ways which has been the subject of several researches in recent years. In this paper we present an innovative learning method implemented for Police Force (PF) Agent. This method can cope with the main difficulties that exist in other learning approaches. Different methods used in the literature have been examined. Their drawbacks and possible improvements have led us to the method proposed in this paper which is fast and accurate. The Brain Emotional Learning Based Intelligent Controller (BELBIC) is our solution for learning in this environment. BELBIC is a physiologically motivated approach based on a computational model of amygdale and limbic system. The paper presents the results obtained by the proposed approach, showing the power of BELBIC as a decision making tool in complex and dynamic situation.

Keywords: Emotional learning, rescue, simulation environment, RoboCup, multi-agent system.

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334 Energy-Efficient Electrical Power Distribution with Multi-Agent Control at Parallel DC/DC Converters

Authors: Janos Hamar, Peter Bartal, Daniel T. Sepsi

Abstract:

Consumer electronics are pervasive. It is impossible to imagine a household or office without DVD players, digital cameras, printers, mobile phones, shavers, electrical toothbrushes, etc. All these devices operate at different voltage levels ranging from 1.8 to 20 VDC, in the absence of universal standards. The voltages available are however usually 120/230 VAC at 50/60 Hz. This situation makes an individual electrical energy conversion system necessary for each device. Such converters usually involve several conversion stages and often operate with excessive losses and poor reliability. The aim of the project presented in this paper is to design and implement a multi-channel DC/DC converter system, customizing the output voltage and current ratings according to the requirements of the load. Distributed, multi-agent techniques will be applied for the control of the DC/DC converters.

Keywords: DC/DC converter, energy efficiency, multi-agentcontrol, parallel converters.

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333 Simulation of Ethical Behavior in Urban Transportation

Authors: Ali Reza Honarvar , Naser Ghasem Agaee

Abstract:

For controlling urban transportations, traffic lights show similar behavior for different kinds of vehicles at intersections. Emergency vehicles need special behavior at intersections, so traffic lights should behave in different manner when emergency vehicles approach them. At the present time, intelligent traffic lights control urban transportations intelligently. In this paper the ethical aspect of this topic is considered. A model is proposed for adding special component to emergency vehicles and traffic lights for controlling traffic in ethical manner. The proposed model is simulated by JADE.

Keywords: Ethical traffic control, intelligent transportation, Ethical agent, Multi-agent system.

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332 Contribution to Energy Management in Hybrid Energy Systems Based on Agents Coordination

Authors: Djamel Saba, Fatima Zohra Laallam, Brahim Berbaoui

Abstract:

This paper presents a contribution to the design of a multi-agent for the energy management system in a hybrid energy system (SEH). The multi-agent-based energy-coordination management system (MA-ECMS) is based mainly on coordination between agents. The agents share the tasks and exchange information through communications protocols to achieve the main goal. This intelligent system can fully manage the consumption and production or simply to make proposals for action he thinks is best. The initial step is to give a presentation for the system that we want to model in order to understand all the details as much as possible. In our case, it is to implement a system for simulating a process control of energy management.

Keywords: Multi agents system, hybrid energy system, communications protocols, modelization, simulation, control process, energy management.

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331 Development of Monitoring and Simulation System of Human Tracking System Based On Mobile Agent Technologies

Authors: Kozo Tanigawa, Toshihiko Sasama, Kenichi Takahashi, Takao Kawamura, Kazunori Sugahara

Abstract:

In recent years, the number of the cases of information leaks is increasing. Companies and Research Institutions make various actions against information thefts and security accidents. One of the actions is adoption of the crime prevention system, including the monitoring system by surveillance cameras. In order to solve difficulties of multiple cameras monitoring, we develop the automatic human tracking system using mobile agents through multiple surveillance cameras to track target persons. In this paper, we develop the monitor which confirms mobile agents tracing target persons, and the simulator of video picture analysis to construct the tracking algorithm.

Keywords: Human tracking, mobile agent, monitoring, simulate.

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330 A Study on Mechanical Properties of Fiberboard Made of Durian Rind through Latex with Phenolic Resin as Binding Agent

Authors: W. Wiyaratn, A. Watanapa

Abstract:

This study was aimed to study the probability about the production of fiberboard made of durian rind through latex with phenolic resin as binding agent. The durian rind underwent the boiling process with NaOH [7], [8] and then the fiber from durian rind was formed into fiberboard through heat press. This means that durian rind could be used as replacement for plywood in plywood industry by using durian fiber as composite material with adhesive substance. This research would study the probability about the production of fiberboard made of durian rind through latex with phenolic resin as binding agent. At first, durian rind was split, exposed to light, boiled and steamed in order to gain durian fiber. Then, fiberboard was tested with the density of 600 Kg/m3 and 800 Kg/m3. in order to find a suitable ratio of durian fiber and latex. Afterwards, mechanical properties were tested according to the standards of ASTM and JIS A5905-1994. After the suitable ratio was known, the test results would be compared with medium density fiberboard (MDF) and other related research studies. According to the results, fiberboard made of durian rind through latex with phenolic resin at the density of 800 Kg/m3 at ratio of 1:1, the moisture was measured to be 5.05% with specific gravity (ASTM D 2395-07a) of 0.81, density (JIS A 5905-1994) of 0.88 g/m3, tensile strength, hardness (ASTM D2240), flexibility or elongation at break yielded similar values as the ones by medium density fiberboard (MDF).

Keywords: Durian rind, latex, phenolic resin, medium density fiberboard

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329 Design of Personal Job Recommendation Framework on Smartphone Platform

Authors: Chayaporn Kaensar

Abstract:

Recently, Job Recommender Systems have gained much attention in industries since they solve the problem of information overload on the recruiting website. Therefore, we proposed Extended Personalized Job System that has the capability of providing the appropriate jobs for job seeker and recommending some suitable information for them using Data Mining Techniques and Dynamic User Profile. On the other hands, company can also interact to the system for publishing and updating job information. This system have emerged and supported various platforms such as web application and android mobile application. In this paper, User profiles, Implicit User Action, User Feedback, and Clustering Techniques in WEKA libraries were applied and implemented. In additions, open source tools like Yii Web Application Framework, Bootstrap Front End Framework and Android Mobile Technology were also applied.

Keywords: Recommendation, user profile, data mining, web technology, mobile technology.

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328 Learning to Recommend with Negative Ratings Based on Factorization Machine

Authors: Caihong Sun, Xizi Zhang

Abstract:

Rating prediction is an important problem for recommender systems. The task is to predict the rating for an item that a user would give. Most of the existing algorithms for the task ignore the effect of negative ratings rated by users on items, but the negative ratings have a significant impact on users’ purchasing decisions in practice. In this paper, we present a rating prediction algorithm based on factorization machines that consider the effect of negative ratings inspired by Loss Aversion theory. The aim of this paper is to develop a concave and a convex negative disgust function to evaluate the negative ratings respectively. Experiments are conducted on MovieLens dataset. The experimental results demonstrate the effectiveness of the proposed methods by comparing with other four the state-of-the-art approaches. The negative ratings showed much importance in the accuracy of ratings predictions.

Keywords: Factorization machines, feature engineering, negative ratings, recommendation systems.

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327 Optimizing Mobile Agents Migration Based on Decision Tree Learning

Authors: Yasser k. Ali, Hesham N. Elmahdy, Sanaa El Olla Hanfy Ahmed

Abstract:

Mobile agents are a powerful approach to develop distributed systems since they migrate to hosts on which they have the resources to execute individual tasks. In a dynamic environment like a peer-to-peer network, Agents have to be generated frequently and dispatched to the network. Thus they will certainly consume a certain amount of bandwidth of each link in the network if there are too many agents migration through one or several links at the same time, they will introduce too much transferring overhead to the links eventually, these links will be busy and indirectly block the network traffic, therefore, there is a need of developing routing algorithms that consider about traffic load. In this paper we seek to create cooperation between a probabilistic manner according to the quality measure of the network traffic situation and the agent's migration decision making to the next hop based on decision tree learning algorithms.

Keywords: Agent Migration, Decision Tree learning, ID3 algorithm, Naive Bayes Classifier

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326 A Hybrid Recommender System based on Collaborative Filtering and Cloud Model

Authors: Chein-Shung Hwang, Ruei-Siang Fong

Abstract:

User-based Collaborative filtering (CF), one of the most prevailing and efficient recommendation techniques, provides personalized recommendations to users based on the opinions of other users. Although the CF technique has been successfully applied in various applications, it suffers from serious sparsity problems. The cloud-model approach addresses the sparsity problems by constructing the user-s global preference represented by a cloud eigenvector. The user-based CF approach works well with dense datasets while the cloud-model CF approach has a greater performance when the dataset is sparse. In this paper, we present a hybrid approach that integrates the predictions from both the user-based CF and the cloud-model CF approaches. The experimental results show that the proposed hybrid approach can ameliorate the sparsity problem and provide an improved prediction quality.

Keywords: Cloud model, Collaborative filtering, Hybridrecommender system

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325 An Agent-Based Scheduling Framework for Flexible Manufacturing Systems

Authors: Iman Badr

Abstract:

The concept of flexible manufacturing is highly appealing in gaining a competitive edge in the market by quickly adapting to the changing customer needs. Scheduling jobs on flexible manufacturing systems (FMSs) is a challenging task of managing the available flexibility on the shop floor to react to the dynamics of the environment in real-time. In this paper, an agent-oriented scheduling framework that can be integrated with a real or a simulated FMS is proposed. This framework works in stochastic environments with a dynamic model of job arrival. It supports a hierarchical cooperative scheduling that builds on the available flexibility of the shop floor. Testing the framework on a model of a real FMS showed the capability of the proposed approach to overcome the drawbacks of the conventional approaches and maintain a near optimal solution despite the dynamics of the operational environment.

Keywords: Autonomous agents, Flexible manufacturing systems(FMS), Manufacturing scheduling, Real-time systems.

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324 Secure Internet Connectivity for Dynamic Source Routing (DSR) based Mobile Ad hoc Networks

Authors: Ramanarayana Kandikattu, Lillykutty Jacob

Abstract:

'Secure routing in Mobile Ad hoc networks' and 'Internet connectivity to Mobile Ad hoc networks' have been dealt separately in the past research. This paper proposes a light weight solution for secure routing in integrated Mobile Ad hoc Network (MANET)-Internet. The proposed framework ensures mutual authentication of Mobile Node (MN), Foreign Agent (FA) and Home Agent (HA) to avoid various attacks on global connectivity and employs light weight hop-by-hop authentication and end-to-end integrity to protect the network from most of the potential security attacks. The framework also uses dynamic security monitoring mechanism to monitor the misbehavior of internal nodes. Security and performance analysis show that our proposed framework achieves good security while keeping the overhead and latency minimal.

Keywords: Internet, Mobile Ad hoc Networks, Secure routing.

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323 Experimental Study of the Extraction of Copper(II) from Sulphuric Acid by Means of Sodium Diethyldithiocarbamate (SDDT)

Authors: S.Touati, A.H. Meniai

Abstract:

The present work presents the extraction of copper(II) from sulphuric acid solutions with Sodium diethyldithiocarbamate (SDDT), and six different organic diluents: Dichloromethane, Chloroform, Carbon tetrachloride, Toluene, xylene and Cyclohexane, were tested. The pair SDDT/Chloroform showed to be the most selective in removing the copper cations, and hence was considered throughout the experimental study. The effects of operating parameters such as the initial concentration of the extracting agent, the agitation time, the agitation speed and the acid concentration were considered. For an initial concentration of Cu (II) of 63 ppm in a 0.5 M sulphuric acid solution, both with a mass of the extracting agent of 20 mg, an extraction percentage of about 97.8 % and a distribution coefficient of 44.42 were obtained, respectively, confirming the performance of the SDDT-Chloroform pair.

Keywords: Copper (II), Distribution coefficient, Extraction, SDDT, Sulphuric acid.

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322 Estimated Human Absorbed Dose of 111In-BPAMD as a New Bone-Seeking SPECT-Imaging Agent

Authors: H. Yousefnia, S. Zolghadri

Abstract:

An early diagnosis of bone metastasis is very important for making a right decision on a subsequent therapy. One of the most important steps to be taken initially, for developing a new radiopharmaceutical is the measurement of organ radiation exposure dose. In this study, the dosimetric studies of a novel agent for SPECT-imaging of the bone metastasis, 111In-(4- {[(bis(phosphonomethyl))carbamoyl]methyl}7,10bis(carboxymethyl) -1,4,7,10-tetraazacyclododec-1-yl) acetic acid (111In-BPAMD) complex, have been carried out to estimate the dose in human organs based on the data derived from mice. The radiolabeled complex was prepared with high radiochemical purity in the optimal conditions. Biodistribution studies of the complex was investigated in the male Syrian mice at the selected times after injection (2, 4, 24 and 48 h). The human absorbed dose estimation of the complex was made based on data derived from the mice by the radiation absorbed dose assessment resource (RADAR) method. 111In-BPAMD complex was prepared with high radiochemical purity >95% (ITLC) and specific activities of 2.85 TBq/mmol. Total body effective absorbed dose for 111In-BPAMD was 0.205 mSv/MBq. This value is comparable to the other 111In clinically used complexes. The results show that the dose with respect to the critical organs is satisfactory within the acceptable range for diagnostic nuclear medicine procedures. Generally, 111In-BPAMD has interesting characteristics and it can be considered as a viable agent for SPECT-imaging of the bone metastasis in the near future.

Keywords: In-111, BPAMD, absorbed dose, RADAR.

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321 Study the Effect of Ultrasonic Irradiation and Surfactant/Fe ions Weight Ratio on Morphology and Particle Size of Magnetite Nanoparticles Synthesised by co-precipitation for Medical Application

Authors: S.Saloomeh Azimipour Meibod, Peyman Pourafshary, Hamid Reza Madaah Hosseini

Abstract:

A biocompatible ferrofluid have been prepared by coprecipitation of FeCl2.4H2O and FeCl3.6H2O under ultrasonic irradiation and with NaOH as alkaline agent. Cystein was also used as capping agent in the solution. Magnetic properties of the produced ferrofluid were then determined by VSM test and magnetite nanoparticles were characterized by XRD and TEM techniques. The effect of surfactant to Fe ion weight ratio was also studied during this project by using two different amount of Dextran. Results showed the presence of a biocompatible superparamagnetic ferrofluid including magnetite nanoparticles with particle size ranging under 20 nm. The increase in the surfactant content results in the narrowing of the size distribution and reduction of the particle size and more solution stability.

Keywords: Biocompatibility, Ferrofluid, Nanoparticle, Sizedistribution, Ultrasonic irradiation

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320 Rule-Based Expert System for Headache Diagnosis and Medication Recommendation

Authors: Noura Al-Ajmi, Mohammed A. Almulla

Abstract:

With the increased utilization of technology devices around the world, healthcare and medical diagnosis are critical issues that people worry about these days. Doctors are doing their best to avoid any medical errors while diagnosing diseases and prescribing the wrong medication. Subsequently, artificial intelligence applications that can be installed on mobile devices such as rule-based expert systems facilitate the task of assisting doctors in several ways. Due to their many advantages, the usage of expert systems has increased recently in health sciences. This work presents a backward rule-based expert system that can be used for a headache diagnosis and medication recommendation system. The structure of the system consists of three main modules, namely the input unit, the processing unit, and the output unit.

Keywords: Headache diagnosis system, treatment recommender system, rule-based expert system.

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