Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 30855
Study the Effect of Ultrasonic Irradiation and Surfactant/Fe ions Weight Ratio on Morphology and Particle Size of Magnetite Nanoparticles Synthesised by co-precipitation for Medical Application

Authors: S.Saloomeh Azimipour Meibod, Peyman Pourafshary, Hamid Reza Madaah Hosseini


A biocompatible ferrofluid have been prepared by coprecipitation of FeCl2.4H2O and FeCl3.6H2O under ultrasonic irradiation and with NaOH as alkaline agent. Cystein was also used as capping agent in the solution. Magnetic properties of the produced ferrofluid were then determined by VSM test and magnetite nanoparticles were characterized by XRD and TEM techniques. The effect of surfactant to Fe ion weight ratio was also studied during this project by using two different amount of Dextran. Results showed the presence of a biocompatible superparamagnetic ferrofluid including magnetite nanoparticles with particle size ranging under 20 nm. The increase in the surfactant content results in the narrowing of the size distribution and reduction of the particle size and more solution stability.

Keywords: Nanoparticle, Biocompatibility, ferrofluid, ultrasonic irradiation, Sizedistribution

Digital Object Identifier (DOI):

Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1513


[1] K.L. Ang, S. Venkatraman, R.V. Ramanujan, Mater. Sci. Eng. C 27 (2007) 347.
[2] M. Arruebo, R.F. Pacheco, M.R. Ibarra, J. Santamaria, Nanotoday 2 (2007) 22.
[3] D.K.Kim, Y. Zhang, J. Kehr, T. Klason, B. Bjelke, M. Muhammed, J. Magn. Mater. 255 (2001) 256.
[4] S.Odenbach , Colloids and Surfaces A: Physicochemical and Engineering Aspects, 217 (2003) 171.
[5] Dekker, Dekker Encyclopedia of Nanoscience and Nanotechnology, MARCEL DECCER INC., Vol 2, (2005).
[6] H. Eifert, D. Kupp and B. Gunther, Powder Metallurgy, 43 (2000) 310- 313.
[7] H. Hahn, Nanostructured Materials, 9 (1997) 3-12.
[8] J.M. Markus, Swiss Federal Institute of Technology (ETH), 2000.
[9] V. R. Parkal, Nanostructured Materials, 11 (1999) 369-374.
[10] E. Pollerta, S. Vasseur and E. Duguet, J. Magn. Magn. Mater., ARTICLE IN PRESS, 2007.
[11] D.H. Kim, S.H. Lee, K.N. Kim, K.M. Kim, I.B. Shim and Y.K. Lee J. Magn. Magn. Mater., 293 (2005) 320-327.
[12] E.H. Kim, Y. Ahn and H.S. Lee, Journal of Alloys and Compounds 434 (2007) 633-636.
[13] V.M. Guilherme, P. Corio and J. Rubim, Journal of Electroanalytical Chemistry, 603 (2007) 27-34.
[14] R.Y. Hong, T.T. Pan, Y.P. Han, H.Z. Li, J. Ding and S. Han, J. Magn. Magn. Mater., 310 (2007) 37-47.
[15] G. Gnanaprakash, S. Mahadevan, T. Jayakumar, P. Kalyanasundaram, John Philip and Baldev Raj, Materials Chemistry and Physics, In Press, Corrected Proof, Available online 20 February 2007.
[16] T.N. Brusentsova, N.A. Brusentsov, V.D. Kuznetsov and V.N. Nikiforov, J. Magn. Magn. Mater., 293 (2005) 298-302.
[17] A. Skumiel, J. Magn. Magn. Mater., 307 (2006) 85-90.
[18] O.A. Kuznetsova, O.N. Sorokina, V.G. Leontiev, O.A. Shlyakhtin, A.L. Kovarskia and A.A. Kuznetsov, J. Magn. Magn. Mater., 311 (2007) 204-207.
[19] A. Wijaya, K.A. Brown, J.D. Alper and K.H. Schifferli, J. Magn. Magn. Mater., 309 (2007) 15-19.
[20] J.K. Yang , J.H. Yu , J. Kim and Y.H. Choa, Materials Science and Engineering A 449-451 (2007) 477-479.
[21] A. Bee, R. Massart and S. Neveu, J. Magn. Mater., 149 (1995) 6.
[22] A.K. Gupta and M. Gupta, Biomaterials, 26 (2005) 3995-4021.
[23] R.Y. Hong, B. Feng, L.L. Chen, "Synthesis, characterization and MRI application of dextran-coated Fe3O4 magnetic nanoparticles", Biochemical Engineering Journal, Article in press, (2008).