Search results for: isotropy subgroups.
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 32

Search results for: isotropy subgroups.

32 Correspondence Theorem for Anti L-fuzzy Normal Subgroups

Authors: Jian Tang, Yunfei Yao

Abstract:

In this paper the concept of the cosets of an anti Lfuzzy normal subgroup of a group is given. Furthermore, the group G/A of cosets of an anti L-fuzzy normal subgroup A of a group G is shown to be isomorphic to a factor group of G in a natural way. Finally, we prove that if f : G1 -→ G2 is an epimorphism of groups, then there is a one-to-one order-preserving correspondence between the anti L-fuzzy normal subgroups of G2 and those of G1 which are constant on the kernel of f.

Keywords: Group; anti L-fuzzy subgroups; anti L-fuzzy normal subgroups; cosets of an anti L-fuzzy normal subgroup.

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31 Idiopathic Constipation can be Subdivided in Clinical Subtypes: Data Mining by Cluster Analysis on a Population based Study

Authors: Mauro Giacomini, Stefania Bertone, Carlo Mansi, Pietro Dulbecco, Vincenzo Savarino

Abstract:

The prevalence of non organic constipation differs from country to country and the reliability of the estimate rates is uncertain. Moreover, the clinical relevance of subdividing the heterogeneous functional constipation disorders into pre-defined subgroups is largely unknown.. Aim: to estimate the prevalence of constipation in a population-based sample and determine whether clinical subgroups can be identified. An age and gender stratified sample population from 5 Italian cities was evaluated using a previously validated questionnaire. Data mining by cluster analysis was used to determine constipation subgroups. Results: 1,500 complete interviews were obtained from 2,083 contacted households (72%). Self-reported constipation correlated poorly with symptombased constipation found in 496 subjects (33.1%). Cluster analysis identified four constipation subgroups which correlated to subgroups identified according to pre-defined symptom criteria. Significant differences in socio-demographics and lifestyle were observed among subgroups.

Keywords: Cluster analysis, constipation, data mining, statistical analysis.

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30 Primary subgroups and p-nilpotency of finite groups

Authors: Changwen Li

Abstract:

In this paper, we investigate the influence of Ssemipermutable and weakly S-supplemented subgroups on the pnilpotency of finite groups. Some recent results are generalized.

Keywords: S-semipermutable, weakly S-supplemented, pnilpotent.

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29 Bifurcation Method for Solving Positive Solutions to a Class of Semilinear Elliptic Equations and Stability Analysis of Solutions

Authors: Hailong Zhu, Zhaoxiang Li

Abstract:

Semilinear elliptic equations are ubiquitous in natural sciences. They give rise to a variety of important phenomena in quantum mechanics, nonlinear optics, astrophysics, etc because they have rich multiple solutions. But the nontrivial solutions of semilinear equations are hard to be solved for the lack of stabilities, such as Lane-Emden equation, Henon equation and Chandrasekhar equation. In this paper, bifurcation method is applied to solving semilinear elliptic equations which are with homogeneous Dirichlet boundary conditions in 2D. Using this method, nontrivial numerical solutions will be computed and visualized in many different domains (such as square, disk, annulus, dumbbell, etc).

Keywords: Semilinear elliptic equations, positive solutions, bifurcation method, isotropy subgroups.

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28 (λ, μ)-Intuitionistic Fuzzy Subgroups of Groups with Operators

Authors: Shaoquan Sun, Chunxiang Liu

Abstract:

The aim of this paper is to introduce the concepts of the (λ, μ)-intuitionistic fuzzy subgroups and (λ, μ)-intuitionistic fuzzy normal subgroups of groups with operators, and to investigate their properties and characterizations based on M-group homomorphism.

Keywords: Intuitionistic fuzzy group, , μ)-intuitionistic fuzzy subgroup of groups with operators, , μ)-intuitionistic fuzzy normal subgroup of groups with operators, M-group homomorphism.

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27 The Lower and Upper Approximations in a Group

Authors: Zhaohao Wang, Lan Shu

Abstract:

In this paper, we generalize some propositions in [C.Z. Wang, D.G. Chen, A short note on some properties of rough groups, Comput. Math. Appl. 59(2010)431-436.] and we give some equivalent conditions for rough subgroups. The notion of minimal upper rough subgroups is introduced and a equivalent characterization is given, which implies the rough version of Lagranges Theorem.

Keywords: Lower approximations, Upper approximations, Rough sets, Rough groups, Lagrange

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26 Hybrid Recommender Systems using Social Network Analysis

Authors: Kyoung-Jae Kim, Hyunchul Ahn

Abstract:

This study proposes novel hybrid social network analysis and collaborative filtering approach to enhance the performance of recommender systems. The proposed model selects subgroups of users in Internet community through social network analysis (SNA), and then performs clustering analysis using the information about subgroups. Finally, it makes recommendations using cluster-indexing CF based on the clustering results. This study tries to use the cores in subgroups as an initial seed for a conventional clustering algorithm. This model chooses five cores which have the highest value of degree centrality from SNA, and then performs clustering analysis by using the cores as initial centroids (cluster centers). Then, the model amplifies the impact of friends in social network in the process of cluster-indexing CF.

Keywords: Social network analysis, Recommender systems, Collaborative filtering, Customer relationship management

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25 Time Series Regression with Meta-Clusters

Authors: Monika Chuchro

Abstract:

This paper presents a preliminary attempt to apply classification of time series using meta-clusters in order to improve the quality of regression models. In this case, clustering was performed as a method to obtain subgroups of time series data with normal distribution from the inflow into wastewater treatment plant data, composed of several groups differing by mean value. Two simple algorithms, K-mean and EM, were chosen as a clustering method. The Rand index was used to measure the similarity. After simple meta-clustering, a regression model was performed for each subgroups. The final model was a sum of the subgroups models. The quality of the obtained model was compared with the regression model made using the same explanatory variables, but with no clustering of data. Results were compared using determination coefficient (R2), measure of prediction accuracy- mean absolute percentage error (MAPE) and comparison on a linear chart. Preliminary results allow us to foresee the potential of the presented technique.

Keywords: Clustering, Data analysis, Data mining, Predictive models.

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24 A Genetic Algorithm for Clustering on Image Data

Authors: Qin Ding, Jim Gasvoda

Abstract:

Clustering is the process of subdividing an input data set into a desired number of subgroups so that members of the same subgroup are similar and members of different subgroups have diverse properties. Many heuristic algorithms have been applied to the clustering problem, which is known to be NP Hard. Genetic algorithms have been used in a wide variety of fields to perform clustering, however, the technique normally has a long running time in terms of input set size. This paper proposes an efficient genetic algorithm for clustering on very large data sets, especially on image data sets. The genetic algorithm uses the most time efficient techniques along with preprocessing of the input data set. We test our algorithm on both artificial and real image data sets, both of which are of large size. The experimental results show that our algorithm outperforms the k-means algorithm in terms of running time as well as the quality of the clustering.

Keywords: Clustering, data mining, genetic algorithm, image data.

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23 Some Properties of Superfuzzy Subset of a Fuzzy Subset

Authors: Hassan Naraghi

Abstract:

In this paper, we define permutable and mutually permutable fuzzy subgroups of a group. Then we study their relation with permutable and mutually permutable subgroups of a group. Also we study some properties of fuzzy quasinormal subgroup. We define superfuzzy subset of a fuzzy subset and we study some properties of superfuzzy subset of a fuzzy subset.

Keywords: Permutable fuzzy subgroup, mutually permutable fuzzy subgroup, fuzzy quasinormal subgroup, superfuzzy subset.

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22 Damage Strain Analysis of Parallel Fiber Eutectic

Authors: Jian Zheng, Xinhua Ni, Xiequan Liu

Abstract:

According to isotropy of parallel fiber eutectic, the no- damage strain field in parallel fiber eutectic is obtained from the flexibility tensor of parallel fiber eutectic. Considering the damage behavior of parallel fiber eutectic, damage variables are introduced to determine the strain field of parallel fiber eutectic. The damage strains in the matrix, interphase, and fiber of parallel fiber eutectic are quantitatively analyzed. Results show that damage strains are not only associated with the fiber volume fraction of parallel fiber eutectic, but also with the damage degree.

Keywords: Parallel fiber eutectic, no-damage strain, damage strain, fiber volume fraction, damage degree.

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21 Effect of Fatty Acids in Feed on Levels of Antibody Titers and CD4 and CD8 T-Lymphocyte against Newcastle Disease Virus of Vaccinated Broiler Chicken

Authors: Alaa A. Shamaun Al-Abboodi, Yunis A. A. Bapeer

Abstract:

400 one-day-old male broiler chicks (Ross-308) randomly divided to 2 main groups, 1st main group (GA) was feeding basal diet with medium chain fatty acid (MCFA) at rate of 0.15% and divided to four subgroups, 3 subgroups vaccinated with different routes with Newcastle Disease Virus (NDV) and non-vaccinated group. The 2nd main group (GB) feeding basal diet without MCFA and divided the same as 1st main group. The parameters used in this study included: ND antibody titers at 1, 10, 21, 28, 35 and 42 days of age and values of CD4 and CD8 at 1, 20, 30 and 42 days of age. This experiment detected increase in ND antibodies titers in (G1, G2, G3) groups were fed on basal diet MCFA comparing to groups were fed without adding MCFA (G5, G6, G7) and control groups (G4, G8). The results of cellular immune response (CD4 and CD8) T-cells in broiler chicks indicated that there was obviously significant relationship between dietary Fatty Acid (FA) versus the diet without FA on the level of CD4 parameter, for the entire experimental period. The effect of different ages was statistically significant in creating different values of CD4 level, whereas the CD4 level decreases markedly with age. However, analyzing the data of different vaccination methods, oculonasal method of vaccination led to the highest value of CD4 compared with the oral, S/C and control groups. There were statistical differences in CD8 values due to supplementation of FA versus the basal diet and due to the effect of different age periods. As for the age effect, the CD8 value at 20 days of age was significantly higher than at 42 and 30 days.

Keywords: Broiler, CD4 and CD8, fatty acids, Newcastle disease.

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20 On the Fp-Normal Subgroups of Finite Groups

Authors: Shitian Liu, Deqin Chen

Abstract:

Let G be a finite group, and let F be a formation of finite group. We say that a subgroup H of G is p F -normal in G if there exists a normal subgroup T of G such that HT is a permutable Hall subgroup of G and G G (H

Keywords: Finite group, Fp -normal subgroup, Sylowsubgroup, Maximal subgroup

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19 Fatal Road Accident Causer's Driving Aptitude in Hungary

Authors: A. Juhász, M. Fogarasi

Abstract:

Those causing fatal traffic accidents are traumatized, which negatively influences their cognitive functions and their personality. In order to clarify how much the trauma of causing a fatal accident effects their driving skills and personality traits, the results of a psychological aptitude and a personality test of drivers carelessly causing fatal accidents and of drivers not causing any accidents were compared separately. The sample (N = 354) consists of randomly selected drivers from the Transportation Aptitude and Examination Centre database who caused fatal accidents (Fatal group, n = 177) or did not cause accidents (Control group, n = 177). The aptitude tests were taken between 2014 and 2019. The comparison of the 2 groups was done according to 3 aspects: 1. Categories of aptitude (suitable, restricted, unsuited); 2. Categories of causes (ability, personality, ability and personality) within the restricted or unsuited (altogether: non-suitable subgroups); 3. Categories of ability and personality within the non-suitable subgroups regardless of the cause-category. Within ability deficiency, the two groups include those, whose ability factor is impaired or limited. This is also true in case of personality failure. Compared to the control group, the number of restricted drivers causing fatal accidents is significantly higher (p < .000) and the number of unsuited drivers is higher on a tendency-level (p = .06). Compared to the control group in the fatal non-suitable subgroup, the ratio of restricted suitability and the unsuitability due to ability factors is exclusively significantly lower (p < .000). The restricted suitability and the unsuitability due to personality factors are more significant in the fatal non-suitable subgroup (p < .000). Incapacity due to combination of ability and personality is also significantly higher in the fatal group (p = .002). Compared to the control group both ability and personality factors are also significantly higher in the fatal non-suitable subgroup (p < .000). Overall, the control group is more eligible for driving than drivers who have caused fatalities. The ability and personality factors are significantly higher in the case of fatal accident causers who are non-suitable for driving. Moreover the concomitance of ability and personality factors occur almost exclusively to drivers who caused fatal accidents. Further investigation is needed to understand the causes and how the aptitude test results for the fatal group could improve over time.

Keywords: Aptitude, unsuited, fatal accident, ability, personality.

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18 Predicting Effective Permeability of Nanodielectric Composites Bonded by Soft Magnetic Nanoparticles

Authors: A. Thabet, M. Repetto

Abstract:

Dielectric materials play an important role in broad applications, such as electrical and electromagnetic applications. This research studied the prediction of effective permeability of composite and nanocomposite dielectric materials based on theoretical analysis to specify the effects of embedded magnetic inclusions in enhancing magnetic properties of dielectrics. Effective permeability of Plastics and Glass nanodielectrics have been predicted with adding various types and percentages of magnetic nano-particles (Fe, Ni-Cu, Ni-Fe, MgZn_Ferrite, NiZn_Ferrite) for formulating new nanodielectric magnetic industrial materials. Soft nanoparticles powders that have been used in new nanodielectrics often possess the structure of a particle size in the range of micrometer- to nano-sized grains and magnetic isotropy, e.g., a random distribution of magnetic easy axes of the nanograins. It has been succeeded for enhancing characteristics of new nanodielectric magnetic industrial materials. The results have shown a significant effect of inclusions distribution on the effective permeability of nanodielectric magnetic composites, and so, explained the effect of magnetic inclusions types and their concentration on the effective permeability of nanodielectric magnetic materials.

Keywords: Nanoparticles, Nanodielectrics, Nanocomposites, Effective Permeability, Magnetic Properties.

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17 Ergonomics Aspects of Work with Computers

Authors: Leena Korpinen, Rauno Pääkkönen, Fabriziomaria Gobba

Abstract:

This paper is based on a large questionnaire study. The paper presents how all participants and subgroups (upper- and lower-level white-collar workers) answered the question, “Have you had an ache, pain, or numbness, which you associate with desktop computer use, in the different body parts during the last 12 months?’ 14.6% of participants (19.4% of women and 8.2% of men) reported that they had often or very often physical symptoms in the neck. Even if our results cannot prove a causal relation of symptoms with computer use, show that workers believe that computer use can influence their wellbeing: this is important when devising treatment modalities to decrease these physical symptoms.

Keywords: Ergonomics, work, computer, symptoms.

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16 A Test to Express Diagnostic Cohesion of Football Team

Authors: Alexandra O. Savinkina

Abstract:

We proposed to assess the cohesion of a football team by its subject-goal and subject-value unity according to the A.V. Petrovsky theory. Goal unity was measured by the degree of compliance of the priority targets for various players in the team. Values were estimated by the coincidence of the ideas about a perfect football player. On the basis of the provisional diagnosis of the six teams, we had made the lists of goals and values. The tests were piloted on 35 football teams. The results allowed not only to compare quantitatively the cohesion of the different teams, but also to identify subgroups within the team.

Keywords: Cohesion, football, psychodiagnostic, soccer, sports team, value-orientation unity.

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15 On One Mathematical Model for Filtration of Weakly Compressible Chemical Compound in the Porous Heterogeneous 3D Medium. Part I: Model Construction with the Aid of the Ollendorff Approach

Authors: Sharif E. Guseynov, Jekaterina V. Aleksejeva, Janis S. Rimshans

Abstract:

A filtering problem of almost incompressible liquid chemical compound in the porous inhomogeneous 3D domain is studied. In this work general approaches to the solution of twodimensional filtering problems in ananisotropic, inhomogeneous and multilayered medium are developed, and on the basis of the obtained results mathematical models are constructed (according to Ollendorff method) for studying the certain engineering and technical problem of filtering the almost incompressible liquid chemical compound in the porous inhomogeneous 3D domain. For some of the formulated mathematical problems with additional requirements for the structure of the porous inhomogeneous medium, namely, its isotropy, spatial periodicity of its permeability coefficient, solution algorithms are proposed. Continuation of the current work titled ”On one mathematical model for filtration of weakly compressible chemical compound in the porous heterogeneous 3D medium. Part II: Determination of the reference directions of anisotropy and permeabilities on these directions” will be prepared in the shortest terms by the authors.

Keywords: Porous media, filtering, permeability, elliptic PDE.

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14 Exponential Stability Analysis for Switched Cellular Neural Networks with Time-varying Delays and Impulsive Effects

Authors: Zixin Liu, Fangwei Chen

Abstract:

In this Letter, a class of impulsive switched cellular neural networks with time-varying delays is investigated. At the same time, parametric uncertainties assumed to be norm bounded are considered. By dividing the network state variables into subgroups according to the characters of the neural networks, some sufficient conditions guaranteeing exponential stability for all admissible parametric uncertainties are derived via constructing appropriate Lyapunov functional. One numerical example is provided to illustrate the validity of the main results obtained in this paper.

Keywords: Switched systems, exponential stability, cellular neural networks.

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13 Demographic Factors Influencing Employees’ Salary Expectations and Labor Turnover

Authors: M. Osipova

Abstract:

Thanks to informational technologies development every sphere of economics is becoming more and more datacentralized as people are generating huge datasets containing information on any aspect of their life. Applying research of such data to human resources management allows getting scarce statistics on labor market state including salary expectations and potential employees’ typical career behavior, and this information can become a reliable basis for management decisions. The following article presents results of career behavior research based on freely accessible resume data. Information used for study is much wider than one usually uses in human resources surveys. That is why there is enough data for statistically significant results even for subgroups analysis.

Keywords: Human resources management, labor market, salary expectations, statistics, turnover.

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12 Trabecular Texture Analysis Using Fractal Metrics for Bone Fragility Assessment

Authors: Khaled Harrar, Rachid Jennane

Abstract:

The purpose of this study is the discrimination of 28 postmenopausal with osteoporotic femoral fractures from an agematched control group of 28 women using texture analysis based on fractals. Two pre-processing approaches are applied on radiographic images; these techniques are compared to highlight the choice of the pre-processing method. Furthermore, the values of the fractal dimension are compared to those of the fractal signature in terms of the classification of the two populations. In a second analysis, the BMD measure at proximal femur was compared to the fractal analysis, the latter, which is a non-invasive technique, allowed a better discrimination; the results confirm that the fractal analysis of texture on calcaneus radiographs is able to discriminate osteoporotic patients with femoral fracture from controls. This discrimination was efficient compared to that obtained by BMD alone. It was also present in comparing subgroups with overlapping values of BMD.

Keywords: Osteoporosis, fractal dimension, fractal signature, bone mineral density.

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11 Exponential Stability and Periodicity of a Class of Cellular Neural Networks with Time-Varying Delays

Authors: Zixin Liu, Shu Lü, Shouming Zhong, Mao Ye

Abstract:

The problem of exponential stability and periodicity for a class of cellular neural networks (DCNNs) with time-varying delays is investigated. By dividing the network state variables into subgroups according to the characters of the neural networks, some sufficient conditions for exponential stability and periodicity are derived via the methods of variation parameters and inequality techniques. These conditions are represented by some blocks of the interconnection matrices. Compared with some previous methods, the method used in this paper does not resort to any Lyapunov function, and the results derived in this paper improve and generalize some earlier criteria established in the literature cited therein. Two examples are discussed to illustrate the main results.

Keywords: Cellular neural networks, exponential stability, time varying delays, partitioned matrices, periodic solution.

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10 Biodegradation of Polyhydroxybutyrate-Co- Hydroxyvalerate (PHBV) Blended with Natural Rubber in Soil Environment

Authors: K. Kuntanoo, S. Promkotra, P. Kaewkannetra

Abstract:

According to synthetic plastics obtained from petroleum cause some environmental problems. Therefore, degradable plastics become widely used and studied for replacing the synthetic plastic waste. A biopolymer of poly hydroxybutyrate-co-hydroxyvalerate (PHBV) is subgroups of a main kind of polyhydroxyalkanoates (PHAs). Naturally, PHBV is hard, brittle and low flexible while natural rubber (NR) is high elastic latex. Then, they are blended and the biodegradation of the blended PHBV and NR films were examined in soil environment. The results showed that the degradation occurs predominantly in the bulk of the samples. The order of biodegradability was shown as follows: PHBV> PHBV/NR> NR. After biodegradation, the blended films were characterized by appearance analysis such as Scanning Electron Microscope (SEM), Fourier transform infrared spectroscopy (FTIR) and Differential Scanning Calorimetry (DSC). It was found that the biodegradation mainly occurred at the polymer surface.

Keywords: Biodegradation, polyhydroxyalkanoates (PHAs), Polyhydroxybutyrate-co-hydroxyvalerate (PHBV), natural rubber (NR).

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9 Mining Correlated Bicluster from Web Usage Data Using Discrete Firefly Algorithm Based Biclustering Approach

Authors: K. Thangavel, R. Rathipriya

Abstract:

For the past one decade, biclustering has become popular data mining technique not only in the field of biological data analysis but also in other applications like text mining, market data analysis with high-dimensional two-way datasets. Biclustering clusters both rows and columns of a dataset simultaneously, as opposed to traditional clustering which clusters either rows or columns of a dataset. It retrieves subgroups of objects that are similar in one subgroup of variables and different in the remaining variables. Firefly Algorithm (FA) is a recently-proposed metaheuristic inspired by the collective behavior of fireflies. This paper provides a preliminary assessment of discrete version of FA (DFA) while coping with the task of mining coherent and large volume bicluster from web usage dataset. The experiments were conducted on two web usage datasets from public dataset repository whereby the performance of FA was compared with that exhibited by other population-based metaheuristic called binary Particle Swarm Optimization (PSO). The results achieved demonstrate the usefulness of DFA while tackling the biclustering problem.

Keywords: Biclustering, Binary Particle Swarm Optimization, Discrete Firefly Algorithm, Firefly Algorithm, Usage profile Web usage mining.

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8 Apolipoprotein E Gene Polymorphism and Its Association with Cardiovascular Heart Disease Risk Factors in Type 2 Diabetes Mellitus

Authors: Amani Ashari, Julia Omar, Arif Hashim, Shahrul Hamid

Abstract:

Apolipoprotein E (APOE) gene polymorphism has influence on serum lipids which relates to cardiovascular risk. The purpose of this study was to determine the frequency distribution of APOE alleles among Malaysian Type 2 Diabetes Mellitus (DM) patients with and without coronary artery disease (CAD) and their association with serum lipid profiles. A total of 115 patients were recruited in which 78 patients had Type 2 DM without CAD and 37 patients had Type 2 DM with CAD. The APOE polymorphism was detected by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). The APOE ɛ3 allele was the most common one in both groups. There was no significant association between the APOE genotypes and the CAD status in Type 2 DM using Pearson χ2 test. Further analysis indicated there were no significant differences in all lipid parameters between E2, E3 and E4 subgroups in both groups. The study showed that the E4 allele carriers of Type 2 DM with CAD patients had higher LDL-C level and lower HDL-C level compared to the other allele carriers. However, analyses showed these levels were not statistically different. The study also showed that the Type 2 DM with CAD group with E2 allele had higher triglyceride (TG). In conclusion, further study with larger sample size is needed to confirm role of E4 as a marker of CAD among Type 2 DM patients in Malaysian population.

Keywords: Apolipoprotein E, diabetes mellitus, cardiovascular disease, lipids.

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7 Dicotyledon Weed Quantification Algorithm for Selective Herbicide Application in Maize Crops: Statistical Evaluation of the Potential Herbicide Savings

Authors: Morten Stigaard Laursen, Rasmus Nyholm Jørgensen, Henrik Skov Midtiby, Anders Krogh Mortensen, Sanmohan Baby

Abstract:

This work contributes a statistical model and simulation framework yielding the best estimate possible for the potential herbicide reduction when using the MoDiCoVi algorithm all the while requiring a efficacy comparable to conventional spraying. In June 2013 a maize field located in Denmark were seeded. The field was divided into parcels which was assigned to one of two main groups: 1) Control, consisting of subgroups of no spray and full dose spraty; 2) MoDiCoVi algorithm subdivided into five different leaf cover thresholds for spray activation. In addition approximately 25% of the parcels were seeded with additional weeds perpendicular to the maize rows. In total 299 parcels were randomly assigned with the 28 different treatment combinations. In the statistical analysis, bootstrapping was used for balancing the number of replicates. The achieved potential herbicide savings was found to be 70% to 95% depending on the initial weed coverage. However additional field trials covering more seasons and locations are needed to verify the generalisation of these results. There is a potential for further herbicide savings as the time interval between the first and second spraying session was not long enough for the weeds to turn yellow, instead they only stagnated in growth.

Keywords: Weed crop discrimination, macrosprayer, herbicide reduction, site-specific, sprayer-boom.

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6 Tumor Necrosis Factor-α Regulates Heme Oxygenase-1 Expression in Endothelial Cells via the Phosphorylation of JNK/p38

Authors: Chan-Jung Liang, Shu-Huei Wang, Pei-Jhen Wu, Jaw-Shiun Tsai, Chau-Chung Wu, Yuh-Lien Chen

Abstract:

Heme oxygenase-1 (HO-1), an enzyme degrading heme to carbon monoxide, iron, and biliverdin, has been recognized as playing a crucial role in cellular defense against stressful conditions, not only related to heme release. In the present study, the effects of TNF-a on the expression of heme oxygenase-1 (HO-1) in human aortic endothelial cells (HAECs) as well as the related mechanisms were investigated. 10 ng/mL TNF-α treatment significantly increased HO-1 expression after 6h, then a further increase at 12h and declined at 24h. Treatment with 2 ng/mL of TNF-a after 12 h resulted in a significant increase in HO-1 expression, which peaked at 10 ng/mL, then declined at 20 ng/mL. TNF-α induced HO-1 expression and then HO-1 expression reduced  vascular cell adhesion molecule-1 (VCAM-1) expression. Phosphorylation studies of ERK1/2, JNK, and p38, three subgroups of mitogen-activated protein kinases (MAPKs) demonstrated TNF-α-induced ERK1/2, JNK, and p38 phosphorylation. The increase in HO-1 expression in response to TNF-α treatment was affected by pretreatment with SP600125 (a JNK inhibitor) and SB203580 (a p38 inhibitor), not with PD98059 (an ERK1/2 inhibitor). The expression of HO-1 was stronger in aortas of TNF-α-treated apo-E deficient mice when compared with control mice. These results suggest that low dose of TNF-α treatment notably induced HO-1 expression was mediated through JNK/p38 phosphorylation and may have a protective potential in cardiovascular diseases and inflammatory response through the regulation of HO-1 expression.

Keywords: Heme oxygenase-1 inflammation, endothelial cells, mitogen-activated protein kinases (MAPKs).

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5 Measuring Principal and Teacher Cultural Competency: A Needs Assessment of Three Proximate PreK-5 Schools

Authors: Teresa Caswell

Abstract:

Throughout the United States and within a myriad of demographic contexts, students of color experience the results of systemic inequities as an academic outcome. These disparities continue despite the increased resources provided to students and ongoing instruction-focused professional learning received by teachers. We postulated that lower levels of educator cultural competency are an underlying factor of why resource and instructional interventions are less effective than desired. Before implementing any type of intervention, however, cultural competency needed to be confirmed as a factor in schools demonstrating academic disparities between racial subgroups. A needs assessment was designed to measure levels of individual beliefs, including cultural competency, in both principals and teachers at three neighboring schools verified to have academic disparities. The resulting mixed method study utilized the Optimal Theory Applied to Identity Development (OTAID) model to measure cultural competency quantitatively, through self-identity inventory survey items, with teachers and qualitatively, through one-on-one interviews, with each school’s principal. A joint display was utilized to see combined data within and across school contexts. Each school was confirmed to have misalignments between principal and teacher levels of cultural competency beliefs while also indicating that a number of participants in the self-identity inventory survey may have intentionally skipped items referencing the term oppression. Additional use of the OTAID model and self-identity inventory in future research and across contexts is needed to determine transferability and dependability as cultural competency measures.

Keywords: Cultural competency, identity development, mixed method analysis, needs assessment.

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4 Hydraulic Optimization of an Adjustable Spiral-Shaped Evaporator

Authors: Matthias Feiner, Francisco Javier Fernández García, Michael Arneman, Martin Kipfmüller

Abstract:

To ensure reliability in miniaturized devices or processes with increased heat fluxes, very efficient cooling methods have to be employed in order to cope with small available cooling surfaces. To address this problem, a certain type of evaporator/heat exchanger was developed: It is called a swirl evaporator due to its flow characteristic. The swirl evaporator consists of a concentrically eroded screw geometry in which a capillary tube is guided, which is inserted into a pocket hole in components with high heat load. The liquid refrigerant R32 is sprayed through the capillary tube to the end face of the blind hole and is sucked off against the injection direction in the screw geometry. Its inner diameter is between one and three millimeters. The refrigerant is sprayed into the pocket hole via a small tube aligned in the center of the bore hole and is sucked off on the front side of the hole against the direction of injection. The refrigerant is sucked off in a helical geometry (twisted flow) so that it is accelerated against the hot wall (centrifugal acceleration). This results in an increase in the critical heat flux of up to 40%. In this way, more heat can be dissipated on the same surface/available installation space. This enables a wide range of technical applications. To optimize the design for the needs in various fields of industry, like the internal tool cooling when machining nickel base alloys like Inconel 718, a correlation-based model of the swirl-evaporator was developed. The model is separated into 3 subgroups with overall 5 regimes. The pressure drop and heat transfer are calculated separately. An approach to determine the locality of phase change in the capillary and the swirl was implemented. A test stand has been developed to verify the simulation.

Keywords: Helically-shaped, oil-free, R32, swirl-evaporator, twist flow.

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3 Variations of Body Mass Index with Age in Masters Athletes (World Masters Games)

Authors: Walsh Joe, Climstein Mike, Heazlewood Ian Timothy, Burke Stephen, Kettunen Jyrki, Adams Kent, DeBeliso Mark

Abstract:

Whilst there is growing evidence that activity across the lifespan is beneficial for improved health, there are also many changes involved with the aging process and subsequently the potential for reduced indices of health. The nexus between health, physical activity and aging is complex and has raised much interest in recent times due to the realization that a multifaceted approached is necessary in order to counteract a growing obesity epidemic. By investigating age based trends within a population adhering to competitive sport at older ages, further insight might be gleaned to assist in understanding one of many factors influencing this relationship. BMI was derived using data gathered on a total of 6,071 masters athletes (51.9% male, 48.1% female) aged 25 to 91 years ( =51.5, s =±9.7), competing at the Sydney World Masters Games (2009). Using linear and loess regression it was demonstrated that the usual tendency for prevalence of higher BMI increasing with age was reversed in the sample. This trend in reversal was repeated for both male and female only sub-sets of the sample participants, indicating the possibility of improved prevalence of BMI with increasing age for both the sample as a whole and these individual subgroups. This evidence of improved classification in one index of health (reduced BMI) for masters athletes (when compared to the general population) implies there are either improved levels of this index of health with aging due to adherence to sport or possibly the reduced BMI is advantageous and contributes to this cohort adhering (or being attracted) to masters sport at older ages. Demonstration of this proportionately under-investigated World Masters Games population having an improved relationship between BMI and increasing age over the general population is of particular interest in the context of the measures being taken globally to curb an obesity epidemic.

Keywords: Aging, masters athlete, Quetelet Index, sport.

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