Search results for: Mahendra Kumar Gupta

Authors: Som Nath Sachdeva, Vanita Aggarwal, S. M. Gupta

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Use of concrete paver blocks is becoming increasingly popular. They are used for paving of approaches, paths and parking areas including their application in pre-engineered buildings and pavements. This paper discusses the results of an experimental study conducted on Fly Ash Concrete with the aim to report its suitability for concrete paver blocks. In this study, the effect of varying proportions of fly ash, 20% to 40%, on compressive strength and flexural strength of concrete has been evaluated. The mix designs studied are M-30, M-35, M-40 and M-50. It is observed that all the fly ash based mixes are able to achieve the required compressive and flexural strengths. In comparison to control mixes, the compressive and flexural strengths of the fly ash based mixes are found to be slightly less at 7-days and 28 days and a little more at 90 days.

Keywords: Compressive strength, flexural strength, high volume fly ash concrete, paver blocks.

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Authors: Sitansu Kumar Verma, Soni Yadav, Jitendra Singh, Shraddha, Ajay Kumar

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MicroRNAs (miRNAs), a class of approximately 22 nucleotide long non coding RNAs which play critical role in different biological processes. The mature microRNA is usually 19–27 nucleotides long and is derived from a bigger precursor that folds into a flawed stem-loop structure. Mature micro RNAs are involved in many cellular processes that encompass development, proliferation, stress response, apoptosis, and fat metabolism by gene regulation. Resent finding reveals that certain viruses encode their own miRNA that processed by cellular RNAi machinery. In recent research indicate that cellular microRNA can target the genetic material of invading viruses. Cellular microRNA can be used in the virus life cycle; either to up regulate or down regulate viral gene expression Computational tools use in miRNA target prediction has been changing drastically in recent years. Many of the methods have been made available on the web and can be used by experimental researcher and scientist without expert knowledge of bioinformatics. With the development and ease of use of genomic technologies and computational tools in the field of microRNA biology has superior tremendously over the previous decade. This review attempts to give an overview over the genome wide approaches that have allow for the discovery of new miRNAs and development of new miRNA target prediction tools and databases.

Keywords: MicroRNAs, computational tools, gene regulation, databases, RNAi.

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Authors: Manisha Dubey, Pankaj Gupta

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This paper presents a systematic approach for the design of power system stabilizer using genetic algorithm and investigates the robustness of the GA based PSS. The proposed approach employs GA search for optimal setting of PSS parameters. The performance of the proposed GPSS under small and large disturbances, loading conditions and system parameters is tested. The eigenvalue analysis and nonlinear simulation results show the effectiveness of the GPSS to damp out the system oscillations. It is found tat the dynamic performance with the GPSS shows improved results, over conventionally tuned PSS over a wide range of operating conditions.

Keywords: Genetic Algorithm, Genetic power system stabilizer, Power system stabilizer, Small signal stability

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Authors: Ayush Chugh, Gaurav Gupta

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Today’s technology is heavily dependent on web applications. Web applications are being accepted by users at a very rapid pace. These have made our work efficient. These include webmail, online retail sale, online gaming, wikis, departure and arrival of trains and flights and list is very long. These are developed in different languages like PHP, Python, C#, ASP.NET and many more by using scripts such as HTML and JavaScript. Attackers develop tools and techniques to exploit web applications and legitimate websites. This has led to rise of web application security; which can be broadly classified into Declarative Security and Program Security. The most common attacks on the applications are by SQL Injection and XSS which give access to unauthorized users who totally damage or destroy the system. This paper presents a detailed literature description and analysis on Web Application Security, examples of attacks and steps to mitigate the vulnerabilities.

Keywords: Attacks, Injection, JavaScript, SQL, Vulnerability, XSS.

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Authors: Anshu Gupta

Abstract:

Quality evaluation of urban environment is an integral part of efficient urban environment planning and management. The development of fuzzy set theory (FST) and the introduction of FST to the urban study field attempts to incorporate the gradual variation and avoid loss of information. Urban environmental quality assessment pertain to interpretation and forecast of the urban environmental quality according to the national regulation about the permitted content of contamination for the sake of protecting human health and subsistence environment . A strategic motor vehicle control strategy has to be proposed to mitigate the air pollution in the city. There is no well defined guideline for the assessment of urban air pollution and no systematic study has been reported so far for Indian cities. The methodology adopted may be useful in similar cities of India. Remote sensing & GIS can play significant role in mapping air pollution.

Keywords: GIS, Pollution, Remote Sensing, Urban.

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Authors: Shaina Nagpal, Amit Gupta

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In this work, all optical Stimulated Brillouin Scattering (SBS) generated single sideband with suppressed carrier is presented to provide better efficiency. The generation of single sideband and enhanced carrier power signal using the SBS technique is further used to strengthen the low shifted sideband and to suppress the upshifted sideband. These generated single sideband signals are able to work at high frequency ranges. Also, generated single sideband is validated over 90 km transmission using single mode fiber with acceptable bit error rate. The results for an equivalent are then compared so that the acceptable technique is chosen and also the required quality for the optimum performance of the system is reported.

Keywords: Stimulated Brillouin scattering, radio over fiber, upper side band, quality factor.

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Authors: Motahar Reza, Anadi Sankar Gupta

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An analysis is made of the flow of an incompressible viscoelastic fluid (of small memory) over a porous plate subject to suction or blowing. It is found that velocity at a point increases with increase in the elasticity in the fluid. It is also shown that wall shear stress depends only on suction and is also independent of the material of fluids. No steady solution for velocity distribution exists when there is blowing at the plate. Temperature distribution in the boundary layer is determined and it is found that temperature at a point decreases with increase in the elasticity in the fluid.

Keywords: Viscoelastic fluid, Flow past a porous plate, Heat transfer

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Authors: S. Dey, P. Sibanda, S. Gupta, A. Chakraborty

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The occurrence of high nocturnal surface ozone over a tropical urban area (23̊ 32′16.99″ N and 87̊ 17′ 38.95″ E) is analyzed in this paper. Five incidences of nocturnal ozone maxima are recorded during the observational span of two years (June, 2013 to May, 2015). The maximum and minimum values of the surface ozone during these five occasions are 337.630 μg/m³ and 13.034 μg/m³ respectively. HYSPLIT backward trajectory analyses and wind rose diagrams support the horizontal transport of ozone from distant polluted places. Planetary boundary layer characteristics, concentration of precursor (NO₂) and meteorology are found to play important role in the horizontal and vertical transport of surface ozone during nighttime.

Keywords: Nocturnal ozone, planetary boundary layer, horizontal transport, meteorology, urban area.

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Authors: Ashok Kumar, Vinod Kumar

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Wireless Sensor Networks (WSNs) are used to monitor/observe vast inaccessible regions through deployment of large number of sensor nodes in the sensing area. For majority of WSN applications, the collected data needs to be combined with geographic information of its origin to make it useful for the user; information received from remote Sensor Nodes (SNs) that are several hops away from base station/sink is meaningless without knowledge of its source. In addition to this, location information of SNs can also be used to propose/develop new network protocols for WSNs to improve their energy efficiency and lifetime. In this paper, range free localization protocols for WSNs have been proposed. The proposed protocols are based on weighted centroid localization technique, where the edge weights of SNs are decided by utilizing fuzzy logic inference for received signal strength and link quality between the nodes. The fuzzification is carried out using (i) Mamdani, (ii) Sugeno, and (iii) Combined Mamdani Sugeno fuzzy logic inference. Simulation results demonstrate that proposed protocols provide better accuracy in node localization compared to conventional centroid based localization protocols despite presence of unintentional radio frequency interference from radio frequency (RF) sources operating in same frequency band.

Keywords: localization, range free, received signal strength, link quality indicator, Mamdani fuzzy logic inference, Sugeno fuzzy logic inference.

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Authors: Praveen Kumar, Satish Kumar, Jashanpreet Singh

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Transportation of unrefined crude oil from the production unit to a refinery or large storage area by a pipeline is difficult due to the different properties of crude in various areas. Thus, the design of a crude oil pipeline is a very complex and time consuming process, when considering all the various parameters. There were three very important parameters that play a significant role in the transportation and processing pipeline design; these are: viscosity profile, temperature profile and the velocity profile of waxy crude oil through the crude oil pipeline. Knowledge of the Rheological computational technique is required for better understanding the flow behavior and predicting the flow profile in a crude oil pipeline. From these profile parameters, the material and the emulsion that is best suited for crude oil transportation can be predicted. Rheological computational fluid dynamic technique is a fast method used for designing flow profile in a crude oil pipeline with the help of computational fluid dynamics and rheological modeling. With this technique, the effect of fluid properties including shear rate range with temperature variation, degree of viscosity, elastic modulus and viscous modulus was evaluated under different conditions in a transport pipeline. In this paper, two crude oil samples was used, as well as a prepared emulsion with natural and synthetic additives, at different concentrations ranging from 1,000 ppm to 3,000 ppm. The rheological properties was then evaluated at a temperature range of 25 to 60 °C and which additive was best suited for transportation of crude oil is determined. Commercial computational fluid dynamics (CFD) has been used to generate the flow, velocity and viscosity profile of the emulsions for flow behavior analysis in crude oil transportation pipeline. This rheological CFD design can be further applied in developing designs of pipeline in the future.

Keywords: Natural surfactant, crude oil, rheology, CFD, viscosity.

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Authors: Krishnan V. Pagalthivarthi, Pankaj K. Gupta, Vipin Tyagi, M. R. Ravi

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Dense slurry flow through centrifugal pump casing has been modeled using the Eulerian-Eulerian approach with Eulerian multiphase model in FLUENT 6.1®. First order upwinding is considered for the discretization of momentum, k and ε terms. SIMPLE algorithm has been applied for dealing with pressurevelocity coupling. A mixture property based k-ε turbulence model has been used for modeling turbulence. Results are validated first against mesh independence and experiments for a particular set of operational and geometric conditions. Parametric analysis is then performed to determine the effect on important physical quantities viz. solid velocities, solid concentration and solid stresses near the wall with various operational geometric conditions of the pump.

Keywords: Centrifugal pump casing, Dense slurry, Solidsconcentration, Wall shear stress, Pump geometric parameters.

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Authors: S. K. Gupta, Richa Bansal

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In a deregulated power system structure, power producers and customers share a common transmission network for wheeling power from the point of generation to the point of consumption. All parties in this open access environment may try to purchase the energy from the cheaper source for greater profit margins, which may lead to overloading and congestion of certain corridors of the transmission network. This may result in violation of line flow, voltage and stability limits and thereby undermine the system security. Utilities therefore need to determine adequately their available transfer capability (ATC) to ensure that system reliability is maintained while serving a wide range of bilateral and multilateral transactions. This paper presents power transfer distribution factor based on AC load flow for the determination and enhancement of ATC. The study has been carried out for IEEE 24 bus Reliability Test System.

Keywords: Available Transfer Capability, FACTS devices, Power Transfer Distribution Factors.

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Authors: Neelima Gupta, Seema Aggarwal

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Most of the biclustering/projected clustering algorithms are based either on the Euclidean distance or correlation coefficient which capture only linear relationships. However, in many applications, like gene expression data and word-document data, non linear relationships may exist between the objects. Mutual Information between two variables provides a more general criterion to investigate dependencies amongst variables. In this paper, we improve upon our previous algorithm that uses mutual information for biclustering in terms of computation time and also the type of clusters identified. The algorithm is able to find biclusters with mixed relationships and is faster than the previous one. To the best of our knowledge, none of the other existing algorithms for biclustering have used mutual information as a similarity measure. We present the experimental results on synthetic data as well as on the yeast expression data. Biclusters on the yeast data were found to be biologically and statistically significant using GO Tool Box and FuncAssociate.

Keywords: Biclustering, mutual information.

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Authors: Nidhi Gupta, Sanjoy Das, Khushal Singh

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Mobile Ad hoc Network is a set of self-governing nodes which communicate through wireless links. Dynamic topology MANETs makes routing a challenging task. Various routing protocols are there, but due to various fundamental characteristic open medium, changing topology, distributed collaboration and constrained capability, these protocols are tend to various types of security attacks. Black hole is one among them. In this attack, malicious node represents itself as having the shortest path to the destination but that path not even exists. In this paper, we aim to develop a routing protocol for detection and prevention of black hole attack by modifying AODV routing protocol. This protocol is able to detect and prevent the black hole attack. Simulation is done using NS-2, which shows the improvement in network performance.

Keywords: Ad hoc, AODV, Back Bone, routing, Security.

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Authors: Arvind Bhardwaj, Ajay Gupta, Arun Kanda

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Theory of Constraints has been emerging as an important tool for optimization of manufacturing/service systems. Goldratt in his first book “ The Goal " gave the introduction on Theory of Constraints and its applications in a factory scenario. A large number of production managers around the globe read this book but only a few could implement it in their plants because the book did not explain the steps to implement TOC in the factory. To overcome these limitations, Goldratt wrote this book to explain TOC, DBR and the method to implement it. In this paper, an attempt has been made to summarize the salient features of TOC and DBR listed in the book and the correct approach to implement TOC in a factory setting. The simulator available along with the book was actually used by the authors and the claim of Goldratt regarding the use of DBR and Buffer management to ease the work of production managers was tested and was found to be correct.

Keywords: Drum Buffer Rope (DBR), Optimized ProductionTechnology (OPT), Capacity Constrained Resource (CCR)

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Authors: Swapnil Gupta, C. Pandu Rangan

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A uniquely restricted matching is defined to be a matching M whose matched vertices induces a sub-graph which has only one perfect matching. In this paper, we make progress on the open question of the status of this problem on interval graphs (graphs obtained as the intersection graph of intervals on a line). We give an algorithm to compute maximum cardinality uniquely restricted matchings on certain sub-classes of interval graphs. We consider two sub-classes of interval graphs, the former contained in the latter, and give O(|E|^2) time algorithms for both of them. It is to be noted that both sub-classes are incomparable to proper interval graphs (graphs obtained as the intersection graph of intervals in which no interval completely contains another interval), on which the problem can be solved in polynomial time.

Keywords: Uniquely restricted matching, interval graph, design and analysis of algorithms, matching, induced matching, witness counting.

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Authors: Anjan Kumar Kakati, M. Chandrasekaran, Amitava Mandal, Amit Kumar Singh

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End milling process is one of the common metal cutting operations used for machining parts in manufacturing industry. It is usually performed at the final stage in manufacturing a product and surface roughness of the produced job plays an important role. In general, the surface roughness affects wear resistance, ductility, tensile, fatigue strength, etc., for machined parts and cannot be neglected in design. In the present work an experimental investigation of end milling of aluminium alloy with carbide tool is carried out and the effect of different cutting parameters on the response are studied with three-dimensional surface plots. An artificial neural network (ANN) is used to establish the relationship between the surface roughness and the input cutting parameters (i.e., spindle speed, feed, and depth of cut). The Matlab ANN toolbox works on feed forward back propagation algorithm is used for modeling purpose. 3-12-1 network structure having minimum average prediction error found as best network architecture for predicting surface roughness value. The network predicts surface roughness for unseen data and found that the result/prediction is better. For desired surface finish of the component to be produced there are many different combination of cutting parameters are available. The optimum cutting parameter for obtaining desired surface finish, to maximize tool life is predicted. The methodology is demonstrated, number of problems are solved and algorithm is coded in Matlab®.

Keywords: End milling, Surface roughness, Neural networks.

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Authors: S. Vignesh, N. Vishnu, S. Vigneshwaran, M. Vishnu Anand, Dinesh Kumar Babu, V. R. Sanal Kumar

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Numerical studies have been carried out using a validated two-dimensional standard k-omega turbulence model for the design optimization of a thrust vector control system using shock induced self-impinging supersonic secondary double jet. Parametric analytical studies have been carried out at different secondary injection locations to identifying the highest unsymmetrical distribution of the main gas flow due to shock waves, which produces a desirable side force more lucratively for vectoring. The results from the parametric studies of the case on hand reveal that the shock induced self-impinging supersonic secondary double jet is more efficient in certain locations at the divergent region of a CD nozzle than a case with supersonic single jet with same mass flow rate. We observed that the best axial location of the self-impinging supersonic secondary double jet nozzle with a given jet interaction angle, built-in to a CD nozzle having area ratio 1.797, is 0.991 times the primary nozzle throat diameter from the throat location. We also observed that the flexible steering is possible after invoking ON/OFF facility to the secondary nozzles for meeting the onboard mission requirements. Through our case studies we concluded that the supersonic self-impinging secondary double jet at predesigned jet interaction angle and location can provide more flexible steering options facilitating with 8.81% higher thrust vectoring efficiency than the conventional supersonic single secondary jet without compromising the payload capability of any supersonic aerospace vehicle.

Keywords: Fluidic thrust vectoring, rocket steering, self-impinging secondary supersonic jet, TVC in aerospace vehicles.

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Authors: A.Goel, M. Agrawal, P. Gupta Poddar

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Selected Mapping (SLM) is a PAPR reduction technique, which converts the OFDM signal into several independent signals by multiplication with the phase sequence set and transmits one of the signals with lowest PAPR. But it requires the index of the selected signal i.e. side information (SI) to be transmitted with each OFDM symbol. The PAPR reduction capability of the SLM scheme depends on the selection of phase sequence set. In this paper, we have proposed a new phase sequence set generation scheme based on M-ary chaotic sequence and a mapping scheme to map quaternary data to concentric circle constellation (CCC) is used. It is shown that this method does not require SI and provides better SER performance with good PAPR reduction capability as compared to existing SLMOFDM methods.

Keywords: Orthogonal frequency division multiplexing (OFDM), Peak-to-average power ratio (PAPR), Selected mapping (SLM), Side information (SI)

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Authors: Kadam Bhambri, Neena Gupta

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All optical wavelength conversion is essential in present day optical networks for transparent interoperability, contention resolution, and wavelength routing. The incorporation of all optical wavelength convertors leads to better utilization of the network resources and hence improves the efficiency of optical networks. Wavelength convertors that can work with Dispersion Managed (DM) solitons are attractive due to their superior transmission capabilities. In this paper, wavelength conversion for dispersion managed soliton signals was demonstrated at 100 Gbps through semiconductor optical amplifier and an optical filter. The wavelength conversion was achieved for a 1550 nm input signal to1555nm output signal. The output signal was measured in terms of BER, Q factor and system margin.    

Keywords: All optical wavelength conversion, dispersion managed solitons, semiconductor optical amplifier, cross gain modulation.

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Authors: Nidhi Gupta, Sanjoy Das, Khushal Singh

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A Mobile Ad-hoc Network (MANET) is a self managing network consists of versatile nodes that are capable of communicating with each other without having any fixed infrastructure. These nodes may be routers and/or hosts. Due to this dynamic nature of the network, routing protocols are vulnerable to various kinds of attacks. The black hole attack is one of the conspicuous security threats in MANETs. As the route discovery process is obligatory and customary, attackers make use of this loophole to get success in their motives to destruct the network. In Black hole attack the packet is redirected to a node that actually does not exist in the network. Many researchers have proposed different techniques to detect and prevent this type of attack. In this paper, we have analyzed various routing protocols in this context. Further we have shown a critical comparison among various protocols. We have shown various routing metrics are required proper and significant analysis of the protocol.

Keywords: Black Hole, MANET, Performance Parameters, Routing Protocol.

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Authors: Tapas Kumar Sinha, Joseph Mathew

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Recently T. C. Au-Yeung, C.Au, and P. C. W. Fung [2] have given the solution of the KdV equation [1] to the boundary condition , where b is a constant. We have further extended the method of [2] to find the solution of the KdV equation with asymptotic degeneracy. Via simulations we find both bright and dark Solitons (i.e. Solitons with opposite phases).

Keywords: KdV equation, Asymptotic Degeneracy, Solitons, Inverse Scattering

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Authors: Parvinder S. Sandhu, Jagdeep Singh, Vikas Gupta, Mandeep Kaur, Sonia Manhas, Ramandeep Sidhu

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Prediction of fault-prone modules provides one way to support software quality engineering. Clustering is used to determine the intrinsic grouping in a set of unlabeled data. Among various clustering techniques available in literature K-Means clustering approach is most widely being used. This paper introduces K-Means based Clustering approach for software finding the fault proneness of the Object-Oriented systems. The contribution of this paper is that it has used Metric values of JEdit open source software for generation of the rules for the categorization of software modules in the categories of Faulty and non faulty modules and thereafter empirically validation is performed. The results are measured in terms of accuracy of prediction, probability of Detection and Probability of False Alarms.

Keywords: K-Means, Software Fault, Classification, ObjectOriented Metrics.

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Authors: Gurjit Kaur, Neena Gupta

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In this paper, we have analyzed and compared the performance of various coding schemes. The basic ID prime sequence codes are unique in only dimension, i.e. time slots, whereas 2D coding techniques are not unique by their time slots but with their wavelengths also. In this research, we have evaluated and compared the performance of 1D and 2D coding techniques constructed using prime sequence coding pattern for Optical Code Division Multiple Access (OCDMA) system on a single platform. Analysis shows that 2D prime code supports lesser number of active users than 1D codes, but they are having large code family and are the most secure codes compared to other codes. The performance of all these codes is analyzed on basis of number of active users supported at a Bit Error Rate (BER) of 10-9.

Keywords: CDMA, OCDMA, BER, OOC, PC, EPC, MPC, 2-D PC/PC, λc, λa.

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Authors: Uttam Vijay, Nitin Gupta

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Due to heavy energy constraints in WSNs clustering is an efficient way to manage the energy in sensors. There are many methods already proposed in the area of clustering and research is still going on to make clustering more energy efficient. In our paper we are proposing a minimum spanning tree based clustering using divide and conquer approach. The MST based clustering was first proposed in 1970’s for large databases. Here we are taking divide and conquer approach and implementing it for wireless sensor networks with the constraints attached to the sensor networks. This Divide and conquer approach is implemented in a way that we don’t have to construct the whole MST before clustering but we just find the edge which will be the part of the MST to a corresponding graph and divide the graph in clusters there itself if that edge from the graph can be removed judging on certain constraints and hence saving lot of computation.

Keywords: Algorithm, Clustering, Edge-Weighted Graph, Weighted-LEACH.

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Authors: Vijaya Ilango, Avika Gupta

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Hydrogen fuel is a zero-emission fuel which uses electrochemical cells or combustion in internal engines, to power vehicles and electric devices. Methods of   hydrogen storage for subsequent use span many approaches, including high pressures, cryogenics and chemical compounds that reversibly release H₂ upon heating. Most research into hydrogen storage is focused on storing hydrogen as a lightweight, compact energy carrier for mobile applications. With the accelerating demand for cleaner and more efficient energy sources, hydrogen research has attracted more attention in the scientific community. Until now, full implementation of a hydrogen-based energy system has been hindered in part by the challenge of storing hydrogen gas, especially onboard an automobile. New techniques being researched may soon make hydrogen storage more compact, safe and efficient. In   this overview, few hydrogen storage methods and mechanism of hydrogen uptake in carbon nanotubes are summarized.

Keywords: Carbon nanotubes, Chemisorption, Hydrogen storage, Physisorption.

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Authors: Mandep Kaur, Surbhi Gupta, Parvinder S. Sandhu, Jagdeep Kaur

Abstract:

Steganography meaning covered writing. Steganography includes the concealment of information within computer files [1]. In other words, it is the Secret communication by hiding the existence of message. In this paper, we will refer to cover image, to indicate the images that do not yet contain a secret message, while we will refer to stego images, to indicate an image with an embedded secret message. Moreover, we will refer to the secret message as stego-message or hidden message. In this paper, we proposed a technique called RGB intensity based steganography model as RGB model is the technique used in this field to hide the data. The methods used here are based on the manipulation of the least significant bits of pixel values [3][4] or the rearrangement of colors to create least significant bit or parity bit patterns, which correspond to the message being hidden. The proposed technique attempts to overcome the problem of the sequential fashion and the use of stego-key to select the pixels.

Keywords: Steganography, Stego Image, RGB Image, Cryptography, LSB.

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Authors: Tanuj Kanchan, Anadi Gupta, Kewal Krishan

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Human skull is shown to exhibit numerous sexually dimorphic traits. Estimation of sex is a challenging task especially when a part of skull is brought for medicolegal investigation. The present research was planned to evaluate the sexing potential of the dimensions of foramen magnum in forensic identification by craniometric analysis. Length and breadth of the foramen magnum was measured using Vernier calipers and the area of foramen magnum was calculated. The length, breadth, and area of foramen magnum were found to be larger in males than females. Sexual dimorphism index was calculated to estimate the sexing potential of each variable. The study observations are suggestive of the limited utility of the craniometric analysis of foramen magnum during the examination of skull and its parts in estimation of sex.

Keywords: Forensic Anthropology, Skeletal remains, Identification, Sex estimation, Foramen magnum.

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Authors: Yung-Chuan Lee, Shahram Rahimi, Bidyut Gupta

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In this paper, we introduce an mobile agent framework with proactive load balancing for ambient intelligence (AmI) environments. One of the main obstacles of AmI is the scalability in which the openness of AmI environment introduces dynamic resource requirements on agencies. To mediate this scalability problem, our framework proposes a load balancing module to proactively analyze the resource consumption of network bandwidth and preferred agencies to suggest the optimal communication method to its user. The framework generally formulates an AmI environment that consists of three main components: (1) mobile devices, (2) hosts or agencies, and (3) directory service center (DSC). A preliminary implementation was conducted with NetLogo and the experimental results show that the proposed approach provides enhanced system performance by minimizing the network utilization to provide users with responsive services.

Keywords: Ambient intelligence, load balancing, multiagent systems, ubiquitous computing.

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Authors: S. Gupta, R. Chadha

Abstract:

Five crystal modifications of water insoluble artesunate were generated by recrystallizing it from various solvents with improved physicochemical properties. These generated crystal forms were characterized to select the most potent and soluble form. SEM of all the forms showed changes in external shape leading them to be different morphologically. DSC thermograms of Form III and Form V showed broad endotherm peaks at 83.04oC and 76.96oC prior to melting fusion of drug respectively. Calculated weight loss in TGA revealed that Form III and Form V are methanol and acetone solvates respectively. However, few additional peaks were appeared in XRPD pattern in these two solvate forms. All forms exhibit exothermic behavior in buffer and two solvates display maximum ease of molecular release from the lattice. Methanol and acetone solvates were found to be most soluble forms and exhibited higher antimalarial efficacy showing higher survival rate (83.3%) after 30 days.

Keywords: Artesunate, Crystal modifications, in vivo studies, Recrystallization.

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